KEGG T01009: 733611

Sus scrofa (pig): 733611

Entry

733611            CDS       T01009

Symbol

PPP1CA

Name

(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit

K06269

serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]

Organism

ssc Sus scrofa (pig)

Pathway

ssc03015

mRNA surveillance pathway

ssc04022

cGMP-PKG signaling pathway

ssc04024

cAMP signaling pathway

ssc04114

Oocyte meiosis

ssc04218

Cellular senescence

ssc04261

Adrenergic signaling in cardiomyocytes

ssc04270

Vascular smooth muscle contraction

ssc04390

Hippo signaling pathway

ssc04510

Focal adhesion

ssc04611

Platelet activation

ssc04720

Long-term potentiation

ssc04728

Dopaminergic synapse

ssc04750

Inflammatory mediator regulation of TRP channels

ssc04810

Regulation of actin cytoskeleton

ssc04910

Insulin signaling pathway

ssc04921

Oxytocin signaling pathway

ssc04931

Insulin resistance

ssc05031

Amphetamine addiction

ssc05034

Alcoholism

ssc05168

Herpes simplex virus 1 infection

ssc05205

Proteoglycans in cancer

ssc05415

Diabetic cardiomyopathy

Brite

KEGG Orthology (KO) [BR:ssc00001]
09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    733611 (PPP1CA)
09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    733611 (PPP1CA)
   04024 cAMP signaling pathway
    733611 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    733611 (PPP1CA)
09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    733611 (PPP1CA)
   04218 Cellular senescence
    733611 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    733611 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    733611 (PPP1CA)
09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    733611 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    733611 (PPP1CA)
   04921 Oxytocin signaling pathway
    733611 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    733611 (PPP1CA)
   04270 Vascular smooth muscle contraction
    733611 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    733611 (PPP1CA)
   04720 Long-term potentiation
    733611 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    733611 (PPP1CA)
09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    733611 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    733611 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    733611 (PPP1CA)
   05034 Alcoholism
    733611 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    733611 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    733611 (PPP1CA)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ssc01009]
    733611 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:ssc03021]
    733611 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:ssc03019]
    733611 (PPP1CA)
   03041 Spliceosome [BR:ssc03041]
    733611 (PPP1CA)
Enzymes [BR:ssc01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     733611 (PPP1CA)
Protein phosphatases and associated proteins [BR:ssc01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     733611 (PPP1CA)
Transcription machinery [BR:ssc03021]
Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     733611 (PPP1CA)
Messenger RNA biogenesis [BR:ssc03019]
Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     733611 (PPP1CA)
Spliceosome [BR:ssc03041]
Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    733611 (PPP1CA)

SSDB

Motif

Pfam:

Metallophos STPPase_N

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

Position

2:5120202..5123168

AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK

NT seq 993 nt +upstreamnt +downstreamnt
atgtccgacagcgagaagctcaacctggactctatcatcgggcgcctgctggaagtgcag
ggctcgcggcctggaaagaatgtacagctgacagagaacgagatccgtggtctgtgcctc
aaatcccgggagattttcctgagccagcccatccttctggagctggaggcacccctcaag
atctgcggtgacatccacggccagtactatgaccttctgcggctgttcgagtacggcggc
ttccctccagagagcaactacctgttcctgggggactatgtggaccggggcaagcagtct
ttggagaccatctgcctgctgctggcctataagatcaagtacccggagaacttcttcctg
ctccgtgggaaccacgagtgtgccagcatcaaccgcatctatggcttctacgatgagtgc
aagagacgctacaacatcaagctgtggaaaaccttcactgactgcttcaactgcctgcct
atcgctgccattgtggacgagaagatcttttgctgccacggaggcctgtcccccgacctg
cagtccatggagcagattcggcgtatcatgcggcccacagacgtgcctgaccagggctta
ctgtgtgacctgctgtggtctgaccccgacaaggacgtgcagggctggggcgagaatgac
cgcggcgtctcctttacctttggagcggaggtggtggccaagttcctgcacaagcacgac
ttggatctcatctgccgggcacaccaggtggtagaagatggctacgagttctttgccaag
aggcagctggtgacactcttctcagctcctaactactgcggcgagtttgacaacgcaggc
gccatgatgagcgtggacgagacgctcatgtgctccttccagatcctcaagcccgccgac
aagaacaaggggaaatatgggcagttcagtggcctgaatcctggaggccggcccatcacc
ccaccccgcaactccgccaaagccaagaaatag

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