KEGG   Sus scrofa (pig): 733634
Entry
733634            CDS       T01009                                 
Symbol
AKR1C1
Name
(RefSeq) aldo-keto reductase family 1 member C1
  KO
K04119  aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc00140  Steroid hormone biosynthesis
ssc00590  Arachidonic acid metabolism
ssc00790  Folate biosynthesis
ssc01100  Metabolic pathways
ssc04913  Ovarian steroidogenesis
ssc05208  Chemical carcinogenesis - reactive oxygen species
Module
ssc_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
ssc_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    733634 (AKR1C1)
   00590 Arachidonic acid metabolism
    733634 (AKR1C1)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    733634 (AKR1C1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    733634 (AKR1C1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    733634 (AKR1C1)
Enzymes [BR:ssc01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.51  3(or 17)beta-hydroxysteroid dehydrogenase
     733634 (AKR1C1)
    1.1.1.188  prostaglandin-F synthase
     733634 (AKR1C1)
    1.1.1.213  3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
     733634 (AKR1C1)
    1.1.1.357  3alpha-hydroxysteroid 3-dehydrogenase
     733634 (AKR1C1)
SSDB
Motif
Pfam: Aldo_ket_red
Other DBs
NCBI-GeneID: 733634
NCBI-ProteinID: NP_001038034
Ensembl: ENSSSCG00000011147
UniProt: Q1KLB4
Position
10:65580297..65594998
AA seq 337 aa
MDPKSQRLRLNDGHFIPVLGFGTYAPEEVPKSEALEATKYAIEVGFRHIDSAYLYQNEEQ
VGQAIRSKIADGTVKREDIFYTSKLWATFLRPELVRPALEKSLKNLQLDYVDLYIIHFPV
ALKPGEELLPTDENGKALFDTVDLCRTWEALEKCKDAGLTKSIGVSNFNHQQLERILNKP
GLKYKPVCNQVECHPYLNQSKLLDFCKSRDIIPVAYSALGSQRVKGWVNLNHPVLLEDPV
LHAIAKKHKQTSAVIALRYQLQRGVVVLAKSYNKRRIKENLQVFNFELPPEDMKTIDGLN
QNLRYCDFSYAVGHPDYPFRPRVTHHVFYQNIMLPEL
NT seq 1014 nt   +upstreamnt  +downstreamnt
atggatcccaaaagccagcgtcttcggcttaacgatggtcacttcattcctgtactggga
tttggtacctatgcacctgaagaggttcccaagagtgaagctctggaggccaccaaatat
gccatagaagttgggttccgtcatatcgatagtgcttatttataccaaaatgaagagcag
gttggacaggccattcgaagcaagattgcagatggcaccgtgaagagagaagacatattc
tacacgtcaaagctttgggccactttccttcgaccagagttggtccgaccagccttggaa
aagtccctgaagaatctccaactggactatgtggatctctatattattcattttccagtg
gctctgaagcccggggaggaacttctgccaacagatgaaaacggaaaagcactatttgac
acagtggatctctgtcgcacgtgggaggccttggagaagtgtaaggacgcaggactgacc
aagtccatcggcgtgtccaactttaaccaccaacagctggagaggatcctgaacaagcca
gggctcaagtacaagcccgtctgcaaccaggtggaatgtcatccttacctcaaccagagc
aagctgttggatttctgcaagtcaagagatatcattccagttgcctattctgctctggga
tcccaaagagtaaaaggatgggtgaacctaaaccacccagttctcttggaagacccagtt
cttcatgccattgctaaaaagcacaagcaaacctcagccgtaattgcccttcgctaccag
ctgcagcgcggagttgtggtcctggccaagagttacaataagaggcggatcaaagaaaac
ctgcaggtttttaactttgaattgcctccagaagatatgaaaacaatcgatggcctcaac
caaaatttaagatactgtgatttttcgtatgccgttggtcaccctgactatccatttcga
ccacgagttactcatcatgtattctaccagaacatcatgcttccagagctgtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (25)   
   KEGG COMPOUND (25)   
Chemical reaction (19)   
   KEGG ENZYME (4)   
   KEGG REACTION (15)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (11)   
   RefSeq(nuc) (3)   
   GenBank (4)   
   EMBL (4)   
Protein domain (1)   
   Pfam (1)   
All databases (82)   

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