KEGG   Sus scrofa (pig): 733673
Entry
733673            CDS       T01009                                 
Symbol
PRKN
Name
(RefSeq) E3 ubiquitin-protein ligase parkin
  KO
K04556  parkin [EC:2.3.2.31]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc04120  Ubiquitin mediated proteolysis
ssc04137  Mitophagy - animal
ssc04141  Protein processing in endoplasmic reticulum
ssc05012  Parkinson disease
ssc05014  Amyotrophic lateral sclerosis
ssc05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    733673 (PRKN)
   04120 Ubiquitin mediated proteolysis
    733673 (PRKN)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    733673 (PRKN)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    733673 (PRKN)
   05014 Amyotrophic lateral sclerosis
    733673 (PRKN)
   05022 Pathways of neurodegeneration - multiple diseases
    733673 (PRKN)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ssc04131]
    733673 (PRKN)
   04121 Ubiquitin system [BR:ssc04121]
    733673 (PRKN)
   03029 Mitochondrial biogenesis [BR:ssc03029]
    733673 (PRKN)
Enzymes [BR:ssc01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.31  RBR-type E3 ubiquitin transferase
     733673 (PRKN)
Membrane trafficking [BR:ssc04131]
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    733673 (PRKN)
  Aggrephagy
   Other aggrephagy associated proteins
    733673 (PRKN)
  Xenophagy
   Other xenophagy associated proteins
    733673 (PRKN)
Ubiquitin system [BR:ssc04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   RBR proteins
    733673 (PRKN)
Mitochondrial biogenesis [BR:ssc03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    733673 (PRKN)
SSDB
Motif
Pfam: zf-RING_14 zf-RING_12 ubiquitin IBR Rad60-SLD Rad60-SLD_2 Dsc3_N Crinkler
Other DBs
NCBI-GeneID: 733673
NCBI-ProteinID: NP_001038068
UniProt: Q1WDP3
Position
1:5698508..6731132
AA seq 461 aa
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDLTVQRCD
LDQQSIVHVVLRPQRNGQERGVAAGHRPGRAGREPASLTRVDLSGSVLPGDAVGLAVILQ
DDSADGAAPAGRPADRPTNKSFYVYCKGPCQRVQPGKLRVRCSTCQQATLTLTQGPSCWD
DVLIPNRMSGECQSPNCPGTTAEFFFKCGAHPTSDKETSVALNLITTNSRDITCITCTDI
RSPILVFQCNCRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHF
RILGEEQYNRYQQYGAEECVLQMGGVLCPSPGCGAGLLPEPGQRKVTCEGGNSLGCGLVF
CRDCKESYHEGECSALFEASAAVAQAYRVDQKAAEQARWEEASKETIRKTTKPCPRCHVP
VEKNGGCMHMKCPQPQCQLEWCWNCGWEWNRDCMGDHWFDV
NT seq 1386 nt   +upstreamnt  +downstreamnt
atgatagtgtttgtcaggttcaactccagccatggtttcccagtggaggtcgattctgac
accagcatcttccagctcaaggaggtggttgctaagcgacagggggttccagctgaccag
ttgcgtgtgattttcgcagggaaggagcttaggaatgacttgacagtgcagcgctgtgac
ctggatcagcagagcatcgttcacgtggtgctgcgaccccagagaaatggccaagaaagg
ggcgtggctgcagggcatcgcccggggcgcgcggggcgggagcccgcgagcctgacccgc
gtggacctcagcggctccgtcctccccggggacgccgtgggcctggcggttattctgcag
gatgacagcgccgacggtgccgcgccagctgggaggcccgcagatagaccaaccaacaag
agcttttatgtctattgcaaaggcccctgtcaaagagtgcagccaggaaagctccgcgtg
cggtgcagcacctgccaacaggcaaccctcaccttgactcagggtccttcttgctgggac
gatgtcttgatcccaaaccggatgagtggtgagtgccagtctccaaactgccctgggacc
acagcagaatttttctttaaatgtggagcacacccgacctctgacaaggaaacatcggta
gctttgaacctgatcacaacaaatagccgagacatcacctgcatcacctgtacggacatc
aggagccccatcctggttttccagtgcaactgccgccacgtgatttgcctggactgtttc
cacctgtactgtgtgacgaggctcaatgaccggcagttcgtccatgacccgcagcttggc
tactctctgccttgtgtggctggctgccccaactccttgattaaagagctccatcacttc
aggattcttggagaggagcagtacaaccggtaccagcaatatggtgccgaggaatgcgtg
ctacagatggggggcgtgctgtgccccagccccggctgcggagcggggctgcttccagag
ccaggtcagaggaaagtcacctgtgaagggggcaacagcctgggctgcgggctcgtcttc
tgccgggactgtaaggagtcgtaccacgaaggcgaatgcagcgccctgtttgaggcctca
gcagcggtggctcaggcctacagggttgaccagaaggcagcagagcaggctcggtgggag
gaggcatccaaagagaccatcaggaaaaccaccaagccctgtcctcggtgccatgtgccg
gttgaaaaaaacggtggctgtatgcacatgaagtgcccgcagccccagtgccagctggag
tggtgctggaactgcggctgggagtggaaccgcgactgcatgggggaccactggttcgac
gtgtag

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (25)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
Protein domain (8)   
   Pfam (8)   
All databases (63)   

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