KEGG   Sus scrofa (pig): 751869
Entry
751869            CDS       T01009                                 
Symbol
NFKB1
Name
(RefSeq) nuclear factor NF-kappa-B p105 subunit
  KO
K02580  nuclear factor NF-kappa-B p105 subunit
Organism
ssc  Sus scrofa (pig)
Pathway
ssc01523  Antifolate resistance
ssc04010  MAPK signaling pathway
ssc04014  Ras signaling pathway
ssc04024  cAMP signaling pathway
ssc04062  Chemokine signaling pathway
ssc04064  NF-kappa B signaling pathway
ssc04066  HIF-1 signaling pathway
ssc04071  Sphingolipid signaling pathway
ssc04151  PI3K-Akt signaling pathway
ssc04210  Apoptosis
ssc04211  Longevity regulating pathway
ssc04218  Cellular senescence
ssc04380  Osteoclast differentiation
ssc04613  Neutrophil extracellular trap formation
ssc04620  Toll-like receptor signaling pathway
ssc04621  NOD-like receptor signaling pathway
ssc04622  RIG-I-like receptor signaling pathway
ssc04623  Cytosolic DNA-sensing pathway
ssc04625  C-type lectin receptor signaling pathway
ssc04657  IL-17 signaling pathway
ssc04658  Th1 and Th2 cell differentiation
ssc04659  Th17 cell differentiation
ssc04660  T cell receptor signaling pathway
ssc04662  B cell receptor signaling pathway
ssc04668  TNF signaling pathway
ssc04722  Neurotrophin signaling pathway
ssc04917  Prolactin signaling pathway
ssc04920  Adipocytokine signaling pathway
ssc04926  Relaxin signaling pathway
ssc04931  Insulin resistance
ssc04932  Non-alcoholic fatty liver disease
ssc04933  AGE-RAGE signaling pathway in diabetic complications
ssc04936  Alcoholic liver disease
ssc05010  Alzheimer disease
ssc05022  Pathways of neurodegeneration - multiple diseases
ssc05030  Cocaine addiction
ssc05132  Salmonella infection
ssc05133  Pertussis
ssc05134  Legionellosis
ssc05135  Yersinia infection
ssc05140  Leishmaniasis
ssc05142  Chagas disease
ssc05145  Toxoplasmosis
ssc05146  Amoebiasis
ssc05152  Tuberculosis
ssc05160  Hepatitis C
ssc05161  Hepatitis B
ssc05162  Measles
ssc05163  Human cytomegalovirus infection
ssc05164  Influenza A
ssc05165  Human papillomavirus infection
ssc05166  Human T-cell leukemia virus 1 infection
ssc05167  Kaposi sarcoma-associated herpesvirus infection
ssc05168  Herpes simplex virus 1 infection
ssc05169  Epstein-Barr virus infection
ssc05170  Human immunodeficiency virus 1 infection
ssc05171  Coronavirus disease - COVID-19
ssc05200  Pathways in cancer
ssc05202  Transcriptional misregulation in cancer
ssc05203  Viral carcinogenesis
ssc05206  MicroRNAs in cancer
ssc05207  Chemical carcinogenesis - receptor activation
ssc05208  Chemical carcinogenesis - reactive oxygen species
ssc05212  Pancreatic cancer
ssc05215  Prostate cancer
ssc05220  Chronic myeloid leukemia
ssc05221  Acute myeloid leukemia
ssc05222  Small cell lung cancer
ssc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ssc05321  Inflammatory bowel disease
ssc05415  Diabetic cardiomyopathy
ssc05417  Lipid and atherosclerosis
ssc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    751869 (NFKB1)
   04014 Ras signaling pathway
    751869 (NFKB1)
   04064 NF-kappa B signaling pathway
    751869 (NFKB1)
   04668 TNF signaling pathway
    751869 (NFKB1)
   04066 HIF-1 signaling pathway
    751869 (NFKB1)
   04071 Sphingolipid signaling pathway
    751869 (NFKB1)
   04024 cAMP signaling pathway
    751869 (NFKB1)
   04151 PI3K-Akt signaling pathway
    751869 (NFKB1)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    751869 (NFKB1)
   04218 Cellular senescence
    751869 (NFKB1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    751869 (NFKB1)
   04620 Toll-like receptor signaling pathway
    751869 (NFKB1)
   04621 NOD-like receptor signaling pathway
    751869 (NFKB1)
   04622 RIG-I-like receptor signaling pathway
    751869 (NFKB1)
   04623 Cytosolic DNA-sensing pathway
    751869 (NFKB1)
   04625 C-type lectin receptor signaling pathway
    751869 (NFKB1)
   04660 T cell receptor signaling pathway
    751869 (NFKB1)
   04658 Th1 and Th2 cell differentiation
    751869 (NFKB1)
   04659 Th17 cell differentiation
    751869 (NFKB1)
   04657 IL-17 signaling pathway
    751869 (NFKB1)
   04662 B cell receptor signaling pathway
    751869 (NFKB1)
   04062 Chemokine signaling pathway
    751869 (NFKB1)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    751869 (NFKB1)
   04917 Prolactin signaling pathway
    751869 (NFKB1)
   04926 Relaxin signaling pathway
    751869 (NFKB1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    751869 (NFKB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    751869 (NFKB1)
  09149 Aging
   04211 Longevity regulating pathway
    751869 (NFKB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    751869 (NFKB1)
   05202 Transcriptional misregulation in cancer
    751869 (NFKB1)
   05206 MicroRNAs in cancer
    751869 (NFKB1)
   05207 Chemical carcinogenesis - receptor activation
    751869 (NFKB1)
   05208 Chemical carcinogenesis - reactive oxygen species
    751869 (NFKB1)
   05203 Viral carcinogenesis
    751869 (NFKB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    751869 (NFKB1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    751869 (NFKB1)
   05221 Acute myeloid leukemia
    751869 (NFKB1)
   05220 Chronic myeloid leukemia
    751869 (NFKB1)
   05215 Prostate cancer
    751869 (NFKB1)
   05222 Small cell lung cancer
    751869 (NFKB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    751869 (NFKB1)
   05170 Human immunodeficiency virus 1 infection
    751869 (NFKB1)
   05161 Hepatitis B
    751869 (NFKB1)
   05160 Hepatitis C
    751869 (NFKB1)
   05171 Coronavirus disease - COVID-19
    751869 (NFKB1)
   05164 Influenza A
    751869 (NFKB1)
   05162 Measles
    751869 (NFKB1)
   05168 Herpes simplex virus 1 infection
    751869 (NFKB1)
   05163 Human cytomegalovirus infection
    751869 (NFKB1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    751869 (NFKB1)
   05169 Epstein-Barr virus infection
    751869 (NFKB1)
   05165 Human papillomavirus infection
    751869 (NFKB1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    751869 (NFKB1)
   05135 Yersinia infection
    751869 (NFKB1)
   05133 Pertussis
    751869 (NFKB1)
   05134 Legionellosis
    751869 (NFKB1)
   05152 Tuberculosis
    751869 (NFKB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    751869 (NFKB1)
   05145 Toxoplasmosis
    751869 (NFKB1)
   05140 Leishmaniasis
    751869 (NFKB1)
   05142 Chagas disease
    751869 (NFKB1)
  09163 Immune disease
   05321 Inflammatory bowel disease
    751869 (NFKB1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    751869 (NFKB1)
   05022 Pathways of neurodegeneration - multiple diseases
    751869 (NFKB1)
  09165 Substance dependence
   05030 Cocaine addiction
    751869 (NFKB1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    751869 (NFKB1)
   05418 Fluid shear stress and atherosclerosis
    751869 (NFKB1)
   05415 Diabetic cardiomyopathy
    751869 (NFKB1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    751869 (NFKB1)
   04932 Non-alcoholic fatty liver disease
    751869 (NFKB1)
   04931 Insulin resistance
    751869 (NFKB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    751869 (NFKB1)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    751869 (NFKB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ssc03000]
    751869 (NFKB1)
Transcription factors [BR:ssc03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    751869 (NFKB1)
SSDB
Motif
Pfam: RHD_DNA_bind RHD_dimer Ank_2 Ank Ank_4 Ank_3 Ank_5 Death
Other DBs
NCBI-GeneID: 751869
NCBI-ProteinID: NP_001041697
UniProt: Q0PHA8
Position
8:complement(118391010..118478927)
AA seq 959 aa
MFHLDPLNHTIFNPELFQPEMPLPTADGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGAS
SEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHGEDGICTVTAGPKDMV
VGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQAEGGGDRQLTDREK
EIIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIV
RMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGIWEGFGDFSPTDVHRQFAIVF
KTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDS
FGGGSGAGAGGGGMFGSGGGGGGAGSTGPGYGFPHYGFPTYGGITFHAGTTKSNAGMKHG
TVDTPSKNDPEDCDKSDDREAVNLSGKVTETTEQDKESSNGEDEVHLTYSVGVKEENYRF
QDNLFLEKAMQLAKQHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHA
QLVRDLLEVTSGLISDEIINMRNDLYQTPLHLAVITKQEAVVEDLLRAGADLSLLDRLGN
SVLHLAAKEGHDKILSILLKHKKAALLINHPNGEGLNAIHVAMMSNSLPCLLLLMAAGAD
VNAQERKSGRTALHLAVELDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAA
LLKAAGADPLVENFEPLYDLDDSWDEDGEDEGVVPGTTPLDMATNWQVFDILNGKPYEPE
FTSDDLLAQGDMKQLTEDTKLQLYKLLEIPDPDKNWATLAQKLGLGILNNAFRLSAAPSK
TLMDNYEVSGGTIKELVEALRQMGYTEAIDVIQAAFCTSGTAATSPVKTTSQAHSLPFSP
ASTRQQIDELRDDSICDSGVETSFRKLSFTESLTSSSSLLTLNKVPHDFGQEGPLEGKI
NT seq 2880 nt   +upstreamnt  +downstreamnt
atgtttcatttggatcctttgaatcatacaatatttaatccagaattatttcaaccggag
atgccactgccaacagcagatggcccataccttcaaatattagagcaacctaaacagaga
ggatttcgtttccgttatgtgtgtgaaggcccctcccatggtggactccctggcgcatct
agtgaaaagaacaagaagtcctaccctcaggtcaaaatctgcaactatgttggacctgca
aaggttattgttcagttggtcacaaatggaaaaaacatccacctgcatgcacacagcctg
gtgggaaaacacggagaggatgggatctgcactgtcactgctggacccaaggacatggtg
gtcggctttgcaaacctgggtatacttcatgtgacaaagaaaaaagtatttgaaacactg
gaagcacgaatgacagaggcatgtataaggggctataatcccggacttttggtgcaccct
gatcttgcttatttgcaagcggaaggtggaggggaccggcagctcacagatcgggaaaag
gagatcatccgtcaggcagctcttcagcagacgaaggagatggacctcagcgtggtacgg
ctcatgtttacagctttccttccggacagcacgggcagcttcactaggcgcctggaaccc
gtggtatctgatgccatctatgacagcaaagcccccaatgcgtccaacttgaaaatagta
agaatggacaggacagccggatgtgtaactggaggggaagagatttatcttctctgtgac
aaggttcagaaagatgacatccagattcgattttatgaagaggaagaaaatggtggaatc
tgggaaggatttggagatttttcccccacagacgttcatagacaatttgccatcgtcttc
aaaactccaaagtataaagatgtcaacattacaaaaccagcctctgtgtttgtccaactt
cggaggaagtctgatttggaaactagtgaaccgaaaccttttctctactatcctgaaatc
aaagataaagaggaagtacaaaggaaacggcagaagctcatgcccaatttctcagatagt
ttcggtggcgggagtggggctggagctggaggcggaggcatgtttggcagcggcggtgga
ggagggggtgctggaagtactggaccagggtatggcttcccccactatggatttcctaca
tatggtggaattaccttccatgctggaaccactaaatctaatgctggaatgaagcacgga
actgtagacaccccatctaaaaatgaccctgaggattgtgacaagagtgatgacagagag
gccgtaaatctctctgggaaagtcacagaaaccacagaacaagataaggagtccagcaat
ggagaggatgaggtgcatctgacgtattcagtaggagtaaaggaggagaattacaggttc
caggataacctctttctagagaaggccatgcaacttgccaagcagcacgccaatgccctt
tttgactatgcagtgacaggagatgtgaagatgctgctggctgtccagcgccatctcact
gcagtgcaggatgagaatggggacagtgtcttacacttggcaatcatccaccttcatgct
cagcttgtgagagacctgctagaagtcacatctggtttgatttctgatgaaattatcaac
atgagaaatgatctctaccagacacccttgcacttggcagtgatcaccaagcaggaggct
gtggtggaggacttgctgagggcaggggccgacctgagtcttctggaccgcttgggtaac
tctgttttgcacctcgctgccaaagaaggacatgataaaattctcagtattttactcaag
cacaaaaaggcagcactacttatcaaccaccccaacggtgaaggtctgaacgctattcac
gtggccatgatgagcaacagcttgccgtgtctgctgctgctgatggccgcgggggccgac
gtcaacgcccaggagcggaagtcaggacgcacagcgctgcacctggccgtggagctcgac
aacatctccttggcgggctgcctgctcttggagggtgatgcccatgtagacagcaccacc
tatgatggaactacacccctgcacatagcggccgggagagggtccaccaggctggcagct
ctcctcaaagcagcaggagcagatcccctggtggagaactttgagcctctgtatgacctg
gatgactcgtgggacgaggatggagaggatgaaggcgtcgtgcctggaactacacctcta
gacatggccaccaactggcaggtatttgacatattaaatgggaaaccctatgagccagag
tttacatcggatgatttactcgcacaaggagacatgaaacagctgactgaagatacaaag
ttacagctctacaagttgctagaaattcctgatcctgacaaaaactgggctaccctggca
cagaaattaggtctggggatactgaataatgccttccggctgagtgctgctccttccaaa
actctcatggacaactacgaggtctccggggggacaataaaggagctggtggaggccctg
agacagatgggctacactgaagccattgacgtgatccaggcggccttctgcacctcagga
accgcagccaccagccctgtgaagaccacctctcaggcccactcgctgcccttctcgcct
gcctccacaaggcagcaaatagacgagctccgggatgacagcatctgtgacagcggcgtg
gagacgtcctttcgcaaactcagcttcacagagtctctgaccagcagcagctcattgcta
actctcaacaaagtgccccacgatttcgggcaggaaggacctctagaaggcaaaatttag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (73)   
   KEGG PATHWAY (73)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
Protein domain (8)   
   Pfam (8)   
All databases (110)   

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