KEGG   Thermotoga maritima MSB8: TM0236
Entry
TM0236            CDS       T00022                                 
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
tma  Thermotoga maritima MSB8
Pathway
tma00300  Lysine biosynthesis
tma00550  Peptidoglycan biosynthesis
tma01100  Metabolic pathways
tma01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:tma00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    TM0236
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    TM0236
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    TM0236
Enzymes [BR:tma01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     TM0236
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase
Other DBs
NCBI-ProteinID: AAD35327
UniProt: Q9WY78
Structure
Position
complement(250621..251901)
AA seq 426 aa
MKDLLTRRFVLNSKEVREGDVFVAVKGKRFDGHDFIDEALRNGAYAIIAERKTVNSDRIF
LVESSVDTLAKLAREKLGNFSGTVVGVTGSSGKTTTKEILYNLLKNKRSVFKTPGNMNTE
YGLPLSILNDYKGEEILVLEMAASRPGDIAHLCKIAPPDVAVLLNVGSAHLEFFGTRERI
METKMEIIKHSKENAIAVTLFDDPDLRKEVPRYRNTLFFGKEGGDSVLKDWWYYEGSTIA
EFEAFDSLFTVKLSGYWNGGQLLNIAASLCVMRTLGETVDIFDLASLKTVPGRFNVREKK
GVLIVDDTYNASPEAFQTSIEALLRFPGKKFAVVGAMKELGERSKEFHEELGERLNVLDG
VYVFLSEPEAEWIKSKKIILKSDDPEKIAKDLATRVKKGDVVLFKASRAVRIERVLEMFE
KELEKR
NT seq 1281 nt   +upstreamnt  +downstreamnt
atgaaagatctactcacaaggcgtttcgttctgaattcgaaagaagtgagagaaggtgac
gtgttcgtcgccgtgaaagggaaaagattcgatggtcacgattttatagatgaagccctc
aggaacggcgcttatgcgatcattgccgagagaaaaacggtgaattctgatagaatcttt
ctcgtagaaagttccgttgacacgcttgctaagctggcccgagaaaagctcgggaatttt
tccggtacagtcgttggtgtaacaggttcatcgggaaaaaccaccacgaaagaaatattg
tacaaccttctcaaaaacaagagaagtgtcttcaaaacaccgggaaacatgaacacggag
tacgggttgccactctccattctcaacgactacaaaggagaagaaatcctggttctcgaa
atggccgcgagcaggcccggtgatatcgctcacctgtgtaaaatcgctcctccggatgtc
gccgttctcctcaacgttggaagcgctcacctcgagttttttggaacacgagaaagaatc
atggaaaccaagatggagatcatcaagcactcgaaagaaaatgcgatagccgtaacactc
tttgacgatcctgatctgagaaaagaagtgcctcgctacagaaatacactgttcttcggc
aaagaaggcggtgactcggttctaaaggattggtggtactatgagggttccacgatcgca
gagttcgaagcttttgattctcttttcacagtgaaactctccggatactggaatggaggg
caacttctgaacatcgccgcttctctgtgtgtcatgagaactttgggcgaaactgtggat
atcttcgatcttgccagcctgaaaacagttcccggccgtttcaacgtgagagaaaaaaaa
ggtgtgctgatcgtggatgatacgtacaacgcaagccctgaagcgtttcaaacttccata
gaggcgcttcttcgtttccccggaaagaaattcgctgttgtgggagcgatgaaagagctc
ggggagaggtcgaaggagtttcacgaagaactgggagagagattgaacgttctggatggg
gtgtatgttttcttgtcagaacccgaagcagaatggatcaagtccaaaaagatcatcctg
aagtcagacgatcccgaaaagatagcgaaagatctcgccaccagggtaaaaaaaggggat
gtggttctcttcaaagcttcaagagcggtgagaatagaaagagttctggaaatgtttgaa
aaggagctggagaaaagatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG ORTHOLOGY (1)   
   RefGene (29)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
3D Structure (1)   
   PDB (1)   
Protein domain (3)   
   Pfam (3)   
All databases (55)   

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