KEGG   Thermotoga maritima MSB8: TM0259
Entry
TM0259            CDS       T00022                                 
Name
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
tma  Thermotoga maritima MSB8
Pathway
tma00470  D-Amino acid metabolism
tma00550  Peptidoglycan biosynthesis
tma01100  Metabolic pathways
tma01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:tma00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    TM0259
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    TM0259
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    TM0259
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:tma01011]
    TM0259
Enzymes [BR:tma01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     TM0259
Peptidoglycan biosynthesis and degradation proteins [BR:tma01011]
 Precursor biosynthesis
  Amino acid ligase
   TM0259
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp_3 ATP-grasp_4 ATP-grasp CPSase_L_D2 RimK GARS_A
Other DBs
NCBI-ProteinID: AAD35347
UniProt: P46805
Position
268747..269658
AA seq 303 aa
MRVALLMGGVSREREISLRSGERVKKALEKLGYEHTVFDVREDFLKKVDQLKSFDVVFNV
LHGTFGEDGTLQAILDFLGIRYTGSDAFSSMICFDKLVTYRFLKGTVEIPDFVEIKEFMK
TSPLGYPCVVKPRREGSSIGVFVCESDEEFQHALKEDLPRYGSVIVQKYIPGREMTVSIL
ETEKGFEILPVLELRPKRRFYDYVAKYTKGETEFILPAPLNPSEERLVKEMALKAFVEAG
CRGFGRVDGIFSDGRFYFLEINTVPGLTETSDLPASAKAGGIEFEELVEIILKSAFLKEG
VRV
NT seq 912 nt   +upstreamnt  +downstreamnt
gtgagagtggctctcctgatgggaggagtgtcgagggaaagggaaatctctctgagaagc
ggagaaagggtaaaaaaggctcttgaaaaactcgggtatgaacacaccgtttttgacgtt
agagaagattttctcaagaaagtggatcagttgaaaagttttgatgtggtcttcaacgtt
ctccatggaactttcggtgaggatggaacgcttcaggcaattctggattttttggggatc
agatacaccgggtccgatgcgttttcaagcatgatatgttttgataaactcgtgacttac
aggtttttaaagggcaccgtcgagatacctgattttgtggagatcaaggaattcatgaaa
acttctccccttgggtatccctgtgtggtaaaaccgaggagagagggttcaagcatagga
gtgttcgtttgtgaatcggatgaagagtttcaacacgcgctcaaggaagatttaccacga
tatgggagtgtgattgttcaaaagtacatccccggcagggaaatgactgtgtctatttta
gaaacggaaaagggcttcgaaattcttcccgttcttgagttgcgaccaaagcgtcgtttc
tacgattacgttgcgaagtacacgaaaggtgaaacggagttcattcttcctgctcctttg
aatccttcagaagaacgccttgtcaaggaaatggctctcaaagcgtttgtagaagctggt
tgcagaggttttgggagggtggatggtattttcagcgatggcaggttctactttctggaa
atcaacacggtaccgggtctaacggaaaccagtgatctcccagcgagcgcgaaagcggga
ggaatcgagttcgaggaactcgttgagatcatcttaaagagcgcttttttgaaagaaggg
gtgagagtatga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (8)   
   Pfam (8)   
All databases (36)   

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