KEGG   Thermotoga maritima MSB8: TM0381
Entry
TM0381            CDS       T00022                                 
Name
(GenBank) dihydrolipoamide dehydrogenase
  KO
K00382  dihydrolipoyl dehydrogenase [EC:1.8.1.4]
Organism
tma  Thermotoga maritima MSB8
Pathway
tma00010  Glycolysis / Gluconeogenesis
tma00020  Citrate cycle (TCA cycle)
tma00260  Glycine, serine and threonine metabolism
tma00280  Valine, leucine and isoleucine degradation
tma00380  Tryptophan metabolism
tma00620  Pyruvate metabolism
tma00630  Glyoxylate and dicarboxylate metabolism
tma00640  Propanoate metabolism
tma00785  Lipoic acid metabolism
tma01100  Metabolic pathways
tma01110  Biosynthesis of secondary metabolites
tma01120  Microbial metabolism in diverse environments
tma01200  Carbon metabolism
tma01210  2-Oxocarboxylic acid metabolism
tma01240  Biosynthesis of cofactors
Module
tma_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
tma_M00621  Glycine cleavage system
Brite
KEGG Orthology (KO) [BR:tma00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    TM0381
   00020 Citrate cycle (TCA cycle)
    TM0381
   00620 Pyruvate metabolism
    TM0381
   00630 Glyoxylate and dicarboxylate metabolism
    TM0381
   00640 Propanoate metabolism
    TM0381
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    TM0381
   00280 Valine, leucine and isoleucine degradation
    TM0381
   00310 Lysine degradation
    TM0381
   00380 Tryptophan metabolism
    TM0381
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    TM0381
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:tma04147]
    TM0381
Enzymes [BR:tma01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.4  dihydrolipoyl dehydrogenase
     TM0381
Exosome [BR:tma04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   TM0381
SSDB
Motif
Pfam: Pyr_redox_2 Pyr_redox_dim Pyr_redox Pyr_redox_3 DAO HI0933_like GIDA FAD_binding_2 FAD_oxidored NAD_binding_8 FAD_binding_3 NAD_binding_9 Lys_Orn_oxgnase 3HCDH_N Thi4 Lycopene_cycl AlaDh_PNT_C UDPG_MGDP_dh_N Trp_halogenase Amino_oxidase 2-Hacid_dh_C Sigma70_r1_1
Other DBs
NCBI-ProteinID: AAD35466
UniProt: Q9WYL2
Position
400051..401400
AA seq 449 aa
MYDAVIIGGGPGGYVCAIKLAQLGKKVALVEKDALGGTCTNRGCIPTKAMLTVSHLMDEM
KEKASKYGLKVSGVEYDVAAIMKHVQKSVMMSRKGIEYLLKKNGVEVFKGTAVVENKNTV
VVQETGEKLEAKNLVLAHGSVPSVFSPFDIDGVWTSDDVFNLKEFPKSLVIVGGGVIGVE
FATFFGSFGVDVTIVEIAEHILPYEDSDVAEEVKKALKRKGVKILEKTKISSLSKVDDGF
EVALENGETLKAEKVLLAAGRKPNIPEDVKALGVKIEKGVVTDSRMRTNVENVYAIGDIR
SGIMLAHVAMYEGIVAAKNIAGEEEEMDYSAVPSIIFSSPEVASVGVREKDVNPEEVVIS
KFPVSANGRARTMLENIGFAKVIADKKDGTVLGMSIVSPSATDMIMEGVIAVKFRMKAED
LEKAIHPHPTLTETILGALEGVSGKPIHL
NT seq 1350 nt   +upstreamnt  +downstreamnt
atgtacgatgctgtgatcataggaggaggacccggaggttacgtctgcgctataaaactc
gcacagcttggaaagaaggtcgcacttgtcgaaaaagatgccctcgggggaacctgtacc
aacaggggatgcattccaacgaaggcgatgctcacagtctcccatctcatggatgaaatg
aaagagaaagcttcaaagtacggcttgaaagtctcaggagtcgaatacgacgtcgccgcc
ataatgaaacacgttcaaaagagtgtgatgatgtcaagaaagggaatagagtacctgctg
aaaaagaatggggttgaagtcttcaaaggaacggccgtcgtggaaaacaagaacacggtt
gttgtccaggaaacgggagagaaactggaagcaaagaatcttgttctcgcacacggatcc
gttccctccgtgttttctcccttcgatatcgacggagtctggacgagtgatgacgtgttc
aatttgaaagaatttccaaagtcgcttgtgatagtgggcggtggtgtcatcggagttgaa
ttcgcgacgtttttcggttctttcggtgtggatgtgacgatcgttgagatcgcagaacac
atcctcccctatgaagactcagatgtggcagaagaagtgaaaaaggccctcaaaaggaag
ggtgttaagatcctggaaaaaacaaaaatttcctccctgagcaaagtcgatgacggcttt
gaagtcgcactcgaaaatggagaaacccttaaggcagaaaaggtcctgctcgccgcagga
agaaagcccaacataccggaggacgtgaaagctctcggagtgaagatagaaaaaggagtc
gtcactgatagcaggatgagaacgaacgtggaaaacgtttacgcgataggagatatcaga
agtggaatcatgctcgctcatgtggccatgtacgagggaatagtcgctgcaaagaacatc
gcgggagaagaggaagaaatggattactcggccgttccgagtatcatcttctcctctccg
gaagtggcatctgtcggtgtgagagaaaaagacgtgaaccccgaagaagttgtgatctcc
aagttcccagtctccgcaaacggaagggcaagaacgatgcttgaaaacatagggtttgcc
aaggtcatagcggacaagaaagacggaacggttctcggcatgagcatcgtttcaccatcg
gctaccgatatgatcatggaaggtgtcatagccgtgaagttcaggatgaaagcggaagat
ctggagaaagccattcacccgcatccgactttgacagaaaccatactcggggctcttgaa
ggggtctcaggaaaacccattcatctgtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (22)   
   KEGG PATHWAY (15)   
   KEGG MODULE (7)   
Chemical substance (27)   
   KEGG COMPOUND (27)   
Chemical reaction (11)   
   KEGG ENZYME (1)   
   KEGG REACTION (10)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (22)   
   Pfam (22)   
All databases (101)   

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