KEGG   Thermotoga maritima MSB8: TM0547
Entry
TM0547            CDS       T00022                                 
Name
(GenBank) aspartokinase II
  KO
K12524  bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]
Organism
tma  Thermotoga maritima MSB8
Pathway
tma00260  Glycine, serine and threonine metabolism
tma00261  Monobactam biosynthesis
tma00270  Cysteine and methionine metabolism
tma00300  Lysine biosynthesis
tma01100  Metabolic pathways
tma01110  Biosynthesis of secondary metabolites
tma01120  Microbial metabolism in diverse environments
tma01230  Biosynthesis of amino acids
Module
tma_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:tma00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    TM0547
   00270 Cysteine and methionine metabolism
    TM0547
   00300 Lysine biosynthesis
    TM0547
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    TM0547
Enzymes [BR:tma01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     TM0547
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.4  aspartate kinase
     TM0547
SSDB
Motif
Pfam: Homoserine_dh AA_kinase ACT_7 ACT NAD_binding_3 ACT_6
Other DBs
NCBI-ProteinID: AAD35632
UniProt: Q9WZ17
Position
complement(572210..574429)
AA seq 739 aa
MRTYRSFKMFTNSSQGVRKVRVGIAGLGTVGGSIYRILKERGNEIEKRIGEKFIISKVIN
RSPQKYELLGVPKEEIAFDFDDLILNSDVVVEAIGGTDVAVDLVRRALELGRIVVTPNKN
LISEYGNEFSEYIKKRKLFFEASVGGGIPIISLLQDYLIFQKVTRIRGIMNGTTNYILTE
MSKGRHFEEVLKEAQELGYAEADPTNDIEGYDVAYKVSVLAGVVTGRFPGINSVQFEGIT
RIDPEYLKEIVRSGKKLKLIGELDFSTNRYEVRLREVTPEDPFFNVDGVDNAIEVSTDLA
GDFLLKGRGAGGYPTASAVIADLFRVAKYKVLGGAEKFSVVVMKFGGAAISDVEKLEKVA
EKIIKRKKSGVKPVVVLSAMGDTTDHLIELAKTIDENPDPRELDLLLSTGEIQSVALMSI
ALRKRGYKAISFTGNQLKIITDKRYGSARIIDINTDIISRYLKQDFIPVVAGFQGITETG
DITTLGRGGSDLTAIALAYSLGADLCELYKDVDGVYTADPRIVKDARVIKELSWEEMIEL
SRHGAQVLQARAAEFARKYGVKVLIKNAHKETRGTLIWEGTKVENPIVRAVTFEDGMAKV
VLKDVPDKPGVAARIMRTLSQMGVNIDMIIQGMKSGEYNTVAFIVPESQLGKLDIDLLKT
RSEAKEIIIEKGLAKVSIVGVNLTSTPEISATLFETLANEGINIDMISASSSRISVIIDG
KYVEDAVKAIHSRFELDRE
NT seq 2220 nt   +upstreamnt  +downstreamnt
atgagaacatatcgatcctttaaaatgttcacaaactcttcccaaggagtgagaaaagtg
cgggtaggaatcgcagggcttggaactgtgggtggcagtatataccgcatactgaaagaa
agaggaaatgaaatagaaaaaaggatcggtgaaaagttcatcatttcgaaggtgataaat
cgctctcctcaaaagtacgaactgcttggtgttccgaaagaggagatagctttcgatttc
gatgacctcattttgaacagcgatgtggttgtagaagcaataggtggaacggatgtggcg
gtcgatcttgtgcgacgtgccttggagctggggcgaatcgtcgtaactccaaacaaaaat
ctcatctccgaatacggcaacgagttctcagagtacataaaaaaacggaagcttttcttc
gaggcatccgtgggtgggggtattcccatcatatctctccttcaggattatctgatcttt
cagaaagtcaccaggatacgcggaataatgaacggaacgacgaactacatcctcacggag
atgagcaagggaagacatttcgaagaagttctgaaagaagcacaggaacttggctatgct
gaagctgatcccacaaacgacatcgaaggttacgacgtggcgtacaaggtctccgtctta
gctggtgtggtaacgggaaggtttccgggcataaacagcgtgcagttcgagggcataacc
agaatagatccggagtatctaaaagagatcgttcgctccggaaaaaagctgaagctgatc
ggggaactcgatttttcaacaaacagatacgaggtacgtttgagagaagtgacaccagag
gatccgttcttcaacgtggatggtgtagacaacgcgatagaagtttcaactgatctcgct
ggagattttctgctgaagggaaggggagcgggtggatatcccaccgccagcgccgtgata
gcggatcttttcagagtggcgaaatacaaggtgctcggcggtgccgagaagttctcggtt
gtggtgatgaagttcggtggagccgctatctccgatgtggaaaaactcgagaaagtggcc
gagaaaatcataaagagaaagaagagcggtgtgaagcccgttgtcgtgctttccgccatg
ggagacaccacagatcacctgatagaactcgcaaagacgatagatgaaaaccccgacccg
agagaactggatcttctcctctcgacgggagaaatacagagtgtggctctcatgagcatc
gcactcagaaagagaggctacaaagcgatctctttcactggaaatcagctgaagatcata
accgacaagcgttacggatcagcgaggatcatcgacatcaacacggatatcatttcgagg
tatctgaagcaggatttcatacccgttgtcgccgggtttcagggtataaccgaaacgggg
gatatcaccacacttgggaggggtggctcagatctcacagcgatcgctctcgcttactca
ctgggagcggatttgtgtgagctctacaaagacgtggacggggtgtacacggcggatccc
aggatcgtaaaagacgcgcgggtgataaaagagctctcctgggaagagatgatcgagctc
tcgagacacggtgcccaggtgctgcaggcgagagcggcggaattcgcgagaaagtatggt
gtcaaggttctcataaagaacgcacacaaagaaactcgtggaacccttatatgggagggg
acaaaagtggagaatccaatcgtcagggcggttacctttgaagacggtatggcgaaggtt
gttctgaaggatgtaccggacaaacccggtgtcgcagcacggattatgagaactctctct
cagatgggagtgaacatcgacatgatcatacagggaatgaagagcggggagtacaacacc
gtggcgttcatcgttccggagtcccagcttggaaaactcgacatcgatcttctgaaaaca
agaagcgaagcaaaagagatcatcattgaaaaaggactcgcaaaggtctccatcgtaggg
gtgaacctcacttcaacaccggaaatctccgctactctctttgaaacactggcgaacgag
gggatcaacatcgatatgatcagtgcatcgagcagcaggatttctgtgatcatagacgga
aaatacgtggaggatgccgtgaaggcgatacacagcagattcgaactggacagggagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (8)   
   KEGG MODULE (5)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (6)   
   Pfam (6)   
All databases (47)   

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