+C Two-component system KO #

  Two-Component System - Staphylococcus aureus subsp. aureus MW2 (CA-MRSA)

% ! AOmpR family B PhoR-PhoB (phosphate starvation response) C MW1636 phoR; alkaline phosphatase synthesis sensor protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] C MW1637 phoP; alkaline phosphatase synthesis transcriptional regulatory protein K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP B SenX3-RegX3 (phosphate starvation response) B PhoQ-PhoP (magnesium transport) B EnvZ-OmpR (osmotic stress response) B RstB-RstA B CpxA-CpxR (envelope stress response) B CssS-CssR (secretion stress response) B CreC-CreB (phosphate regulation) B BaeS-BaeR (envelope stress response) B BasS-BasR (antimicrobial peptide resistance) B CusS-CusR (copper tolerance) B QseC-QseB (quorum sensing) B KdpD-KdpE (potassium transport) C MW2002 kdpD; sensor protein KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3] C MW2003 kdpE; KDP operon transcriptional regulatory protein KdpE K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE B TorS-TorR (TMAO respiration) B ArcB-ArcA (anoxic redox control) B TctE-TctD (tricarboxylic acid transport) B ResE-ResD (aerobic and anaerobic respiration) C MW1445 srrB; staphylococcal respiratory response protein SrrB K07651 resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3] C MW1446 srrA; staphylococcal respiratory response protein SrrA K07775 resD; two-component system, OmpR family, response regulator ResD B VicK-VicR (cell wall metabolism) C MW0019 vicK; two-component sensor histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] C MW0018 vicR; response regulator K07668 vicR; two-component system, OmpR family, response regulator VicR B MprB-MprA (maintenance of persistent infection) B MtrB-MtrA (osmotic stress response) B PrrB-PrrA (intracellular multiplication) B TrcS-TrcR B NrsS-NrsR (nickel tolerance) B ManS-ManR (manganese homeostasis) B NblS-NblR (photosynthesis) B SasA-RpaAB (circadian timing mediating) B SaeS-SaeR (staphylococcal virulence regulation) C MW0667 saeS; histidine protein kinase K10681 saeS; two-component system, OmpR family, sensor histidine kinase SaeS [EC:2.7.13.3] C MW0668 saeR; response regulator K10682 saeR; two-component system, OmpR family, response regulator SaeR B BceS-BceR (bacitracin transport) B BraS-BraR (bacitracin transport) C MW2544 ORFID:MW2544; hypothetical protein, similar to two-component sensor histidine kinase K19081 braS; two-component system, OmpR family, sensor histidine kinase BraS/BceS [EC:2.7.13.3] C MW2545 ORFID:MW2545; hypothetical protein, similar to two-component response regulator K19082 braR; two-component system, OmpR family, response regulator protein BraR/BceR B GraS-GraR (cationic antimicrobial peptide transport) C MW0622 ORFID:MW0622; hypothetical protein, similar to two-component sensor histidine kinase K19077 graS; two-component system, OmpR family, sensor histidine kinase GraS [EC:2.7.13.3] C MW0621 ORFID:MW0621; hypothetical protein, similar to two-component response regulator K19078 graR; two-component system, OmpR family, response regulator protein GraR B YxdK-YxdJ (antimicrobial peptide response) B ChvG-ChvI (acidity sensing) B CiaH-CiaR B ParS-ParR (polymyxin-adaptive resistance) B AdeS-AdeR B VanS-VanR (VanB type vancomycin resistance) B VanS-VanR (VanE type vancomycin resistance) B VanS-VanR (actinomycete type vancomycin resistance) B ArlS-ArlR (virulence regulation) C MW1304 arlS; putative protein histidine kinase ArlS K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3] C MW1305 truncated-arlR; truncated (putative response regulator ArlR K18941 arlR; two-component system, OmpR family, response regulator ArlR B Ihk-Irr (virulence regulation) B PfeS-PfeR (enterobactin-dependent iron acquisition) B NisK-NisR (lantibiotic biosynthesis) B Unclassified C MW2283 ORFID:MW2283; hypothetical protein, similar to two component histidine kinase sensor K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3] C MW2282 ORFID:MW2282; hypothetical protein, similar to two component response regulator K02483 K02483; two-component system, OmpR family, response regulator # ANarL family B NarX-NarL (nitrate respiration) B NarQ-NarP (nitrate respiration) B UhpB-UhpA (hexose phosphates uptake) B FusK-FusR (virulence regulation) B RcsC-RcsD-RcsB (capsule synthesis) B BarA-UvrY (central carbon metabolism) B ComP-ComA (competence) B EvgS-EvgA (acid and drug tolerance) B DegS-DegU (multicellular behavior control) B DesK-DesR (membrane lipid fluidity regulation) C MW1208 ORFID:MW1208; hypothetical protein, similar to two-component sensor histidine kinase K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3] C MW1209 ORFID:MW1209; hypothetical protein, similar to two-component response regulator K07693 desR; two-component system, NarL family, response regulator DesR B VraS-VraR (cell-wall peptidoglycan synthesis) C MW1825 vraS; two-component sensor histidine kinase K07681 vraS; two-component system, NarL family, vancomycin resistance sensor histidine kinase VraS [EC:2.7.13.3] C MW1824 vraR; two-component response regulator K07694 vraR; two-component system, NarL family, vancomycin resistance associated response regulator VraR B LiaS-LiaR (cell wall stress response) B DevS-DevR (redox response) B NreB-NreC (dissimilatory nitrate/nitrite reduction) C MW2314 ORFID:MW2314; hypothetical protein, similar to two component sensor histidine kinase K07683 nreB; two-component system, NarL family, sensor histidine kinase NreB [EC:2.7.13.3] C MW2313 ORFID:MW2313; hypothetical protein, similar to response regulators of two-component regulatory K07696 nreC; two-component system, NarL family, response regulator NreC B YdfH-YdfI B SalK-SalR B PprA–PprB (biofilm formation) B Unclassified C MW1790 ORFID:MW1790; two-component sensor histidine kinase homolog K02480 K02480; two-component system, NarL family, sensor kinase [EC:2.7.13.3] C MW1789 ORFID:MW1789; two-component response regulator homolog K02479 K02479; two-component system, NarL family, response regulator # ASpo family B KinABCDE-Spo0FA (sporulation control) # ACitB family B CitA-CitB (citrate fermentation) B CitS-CitT (magnesium-citrate transport) B DcuS-DcuR (C4-dicarboxylate metabolism) B DctS-DctR (C4-dicarboxylate transport) B MalK-MalR (malate transport) B Unclassified # ALytTR family B LysS-LysR C MW0236 lytS; two-component sensor histidine kinase K07704 lytS; two-component system, LytTR family, sensor histidine kinase LytS [EC:2.7.13.3] C MW0237 lytR; two-component response regulator K07705 lytT; two-component system, LytTR family, response regulator LytT B AlgZ-AlgR (alginate production) B NatK-NatR (sodium extrusion) B AgrC-AgrA (exoprotein synthesis) C MW1962 agrC; AgrC K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] C MW1963 agrA; accessory gene regulator A K07707 agrA; two-component system, LytTR family, response regulator AgrA B AgrC2-AgrA2 (virulence regulation) B ComD-ComE (competence) B Unclassified # ANtrC family B GlnL-GlnG (nitrogen regulation) B NtrY-NtrX (nitrogen regulation) B HydH-HydG (metal tolerance) B AtoS-AtoC (cPHB biosynthesis) B PilS-PilR (type 4 fimbriae synthesis) B GlrK-GlrR (amino sugar metabolism) B PgtB-PgtA (phosphoglycerate transport) B DctB-DctD (C4-dicarboxylate transport) B KinB-AlgB (alginate production) B HupT-HupR (hydrogenase synthesis regulation) B Unclassified # ACheA family B CheA-CheYBV (chemotaxis) B ChpA-ChpB/PilGH (chemosensory) B PixL-PixGH (positive phototaxis) B WspE-WspRF (chemosensory) B Cph1-Rcp1 (light response) # ACell cycle family B PleC-PleD (cell fate control) B CckA-CtrA/CpdR (cell cycle control) B Hk1-Rrp1 (glycerol uptake and utilization) # ALux family B LuxQN/CqsS-LuxU-LuxO (quorum sensing) # ALuxR family B DctS-DctR (C4-dicarboxylate transport) B TtrS-TtrR (tetrathionate respiration) B FixL-FixJ (nitrogen fixation) B SsrA-SsrB # AOther families B FlrB-FlrC (polar flagellar synthesis) B AauS-AauR (acidic amino acids utilization) B SLN1-YPD1-SSK1/SKN7 (osmosensing) B RpfC-RpfG (cell-to-cell signaling) B GlnK-GlnL (glutamine utilization) B HspS-HspR (hexose phosphates uptake) C MW0199 ORFID:MW0199; hypothetical protein, similar to two-component sensor histidine kinase K25212 hptS; two-component system, sensor histidine kinase HptS [EC:2.7.13.3] C MW0198 ORFID:MW0198; hypothetical protein, similar to two-component response regulator K25213 hptR; two-component system, response regulator HptR B YesM-YesN B CikA B RegB-RegA (redox response) B FitF-FitH (insecticidal toxin regulation) B PhcS-PhcRQ B SagS-HptB-HsbR (swarming activity and biofilm formation) B PdtaS-PdtaR B NasS-NasT B Unclassified ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023