+F Repair protein KO
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DNA Repair and Recombination Proteins - Salmonella enterica subsp. enterica serovar Paratyphi A ATCC9150
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SPA1225 ogt; O6-methylguanine-DNA-alkyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SPA2032 phrB; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E SPA0271 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SPA2973 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SPA1400 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D SPA0139 mutT; 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SPA3583 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SPA1225 ogt; O6-methylguanine-DNA-alkyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SPA0599 ada; ADA regulatory protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D SPA2032 phrB; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D SPA0600 alkB; AlkB protein K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E SPA0271 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SPA3080 mug; G/U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E SPA0742 alkA; DNA-3-methyladenine glycosidase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E SPA2973 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SPA3494 tag; 3-methyladenine DNA glycosylase I, constitutive K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E SPA3578 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E SPA2015 nei; endonuclease VIII, DNA N-glycosylase with an AP lyase activity K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E SPA1400 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E SPA1542 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E SPA0648 nfo; endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E SPA4005 nfi; putative endonuclease K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E SPA2910 recJ; single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E SPA0438 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E SPA3591 yicF; putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E SPA3840 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E SPA4071 uvrA; excision nuclease subunit A K03701 uvrA; excinuclease ABC subunit A
E SPA1954 uvrB; excision nuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E SPA0923 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E SPA1535 conserved hypothetical protein K05984 cho; excinuclease Cho [EC:3.1.25.-]
E SPA3792 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SPA3840 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E SPA0438 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E SPA3591 yicF; putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F SPA3991 rpoB; DNA-directed RNA polymerase, beta-subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F SPA3992 rpoC; DNA-directed RNA polymerase, beta'-subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F SPA3281 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F SPA3593 rpoZ; DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F SPA1634 mfd; transcription-repair coupling factor (TrcF) K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E SPA2766 mutS; DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E SPA4176 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E SPA2870 mutH; DNA mismatch repair protein K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E SPA0804 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E SPA0355 xseA; exodeoxyribonuclease large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E SPA2299 xseB; exodeoxyribonuclease small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
E SPA0991 exoX; exodeoxyribonuclease X K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
D DNA polymerase III holoenzyme
E SPA0238 dnaE; DNA polymerase III, alpha chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E SPA3681 dnaN; DNA polymerase III beta-subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SPA4277 holC; DNA polymerase III, chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E SPA2088 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E SPA1650 holB; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E SPA2505 dnaQ; DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SPA2238 dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E SPA4371 holD; DNA polymerase III, psi subunit K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
E SPA0993 holE; DNA polymerase III, theta subunit K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
D DNA ligase
E SPA0438 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E SPA3591 yicF; putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E SPA3792 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SPA4072 ssb; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E SPA2591 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E SPA3349 dam; DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E SPA2624 putative phage gene K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E SPA0879 vsr; patch repair protein K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E SPA2859 recB; exonuclease V subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E SPA2861 recC; exonuclease V subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E SPA2858 recD; exonuclease V alpha-subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E SPA2687 recA; RecA protein K03553 recA; recombination protein RecA
E SPA0974 ruvA; Holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E SPA0975 ruvB; Holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SPA0971 ruvC; crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E SPA2401 rus; hypothetical protein K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
E SPA3938 priA; primosomal protein replication factor K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E SPA4209 priB; primosomal replication protein N K02686 priB; primosomal replication protein N
E SPA2241 priC; primosomal replication protein N K04067 priC; primosomal replication protein N''
E SPA4358 dnaT; primosomal protein I K02317 dnaT; DNA replication protein DnaT
E SPA0804 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E SPA2328 sbcC; exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E SPA2327 sbcD; exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E SPA2687 recA; RecA protein K03553 recA; recombination protein RecA
E SPA4389 radA; putative DNA repair protein K04485 radA; DNA repair protein RadA/Sms
E SPA3680 recF; recF protein K03629 recF; DNA replication and repair protein RecF
E SPA3596 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SPA2910 recJ; single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E SPA0286 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E SPA2236 recR; recombination protein RecR K06187 recR; recombination protein RecR
E SPA2543 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E SPA2331 rdgC; recombination associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E SPA0974 ruvA; Holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E SPA0975 ruvB; Holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SPA0971 ruvC; crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E SPA2794 conserved hypothetical protein K15342 cas1; CRISP-associated protein Cas1
E SPA0627 yejH; putative helicase K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E SPA2328 sbcC; exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E SPA2327 sbcD; exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F SPA0592 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F SPA3679 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SPA1162 topA; DNA topoisomerase I, omega protein I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F SPA4007 hupA; histone like DNA-binding protein HU-alpha (NS2) (HU-2) K05787 hupA; DNA-binding protein HU-alpha
F SPA2271 hupB; DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F SPA2910 recJ; single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F SPA0286 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F SPA2236 recR; recombination protein RecR K06187 recR; recombination protein RecR
F SPA0438 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F SPA3591 yicF; putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F SPA3252 fis; Fis DNA-binding protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F SPA1504 himA; integration host factor alpha-subunit K04764 ihfA; integration host factor subunit alpha
F SPA1816 himD; integration host factor beta-subunit (IHF-beta) K05788 ihfB; integration host factor subunit beta
E Supressor
F SPA0804 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F SPA3799 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SPA4071 uvrA; excision nuclease subunit A K03701 uvrA; excinuclease ABC subunit A
F SPA1954 uvrB; excision nuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F SPA1127 hns; DNA-binding protein (histone-like protein Hlp-II) K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D SPA2442 dinP; hypothetical protein DinP (DNA damage-inducible protein) K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D SPA0873 umuC; UmuC protein K03502 umuC; DNA polymerase V
D SPA0872 umuD; UmuD protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D SPA2687 recA; RecA protein K03553 recA; recombination protein RecA
D SPA4054 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D SPA2543 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D SPA0098 polB; DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D SPA4072 ssb; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SPA1689 dinI; damage-inducible protein K12149 dinI; DNA-damage-inducible protein I
D SPA2588 hypothetical protein K12149 dinI; DNA-damage-inducible protein I
D SPA2686 oraA; putative regulatory protein RecX K03565 recX; regulatory protein
D SPA3373 conserved hypothetical protein K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D SPA3753 rep; ATP-dependent DNA helicase K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D SPA1775 helD; helicase IV (75 kD helicase) K03658 helD; DNA helicase IV [EC:5.6.2.4]
D SPA1932 dinG; LexA regulated (SOS) repair enzyme K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D SPA1052 yoaA; putative ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D SPA0139 mutT; 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SPA3583 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SPA0587 nrdA; ribonucleoside-diphosphate reductase 1 alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SPA2665 nrdE; ribonucleoside-diphosphate reductase 2 alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SPA0586 nrdB; ribonucleoside-diphosphate reductase 1 beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024