+F Repair protein KO
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DNA Repair and Recombination Proteins - Streptococcus suis 98HAH33 (serotype 2)
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SSU98_0668 Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E SSU98_1016 Uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SSU98_1068 A/G-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SSU98_0813 Predicted EndoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D SSU98_1033 NTP pyrophosphohydrolase including oxidative damage repair enzymes K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSU98_1161 NTP pyrophosphohydrolase including oxidative damage repair enzymes K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSU98_2008 NTP pyrophosphohydrolase including oxidative damage repair enzymes K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSU98_0485 putative hydrolase (MutT family) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSU98_2164 MutT/NudX family protein (putative) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSU98_1976 unknown protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSU98_2036 dUTPase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SSU98_0668 Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E SSU98_1016 Uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SSU98_1068 A/G-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SSU98_0062 3-methyladenine DNA glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E SSU98_1409 Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E SSU98_0813 Predicted EndoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E SSU98_0671 putative 3'-exo-deoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E SSU98_1325 Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E SSU98_1197 NAD-dependent DNA ligase (contains BRCT domain type II) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E SSU98_1393 DNA polymerase I - 3'-5' exonuclease and polymerase domain K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E SSU98_1828 Excinuclease ATPase subunit K03701 uvrA; excinuclease ABC subunit A
E SSU98_1038 Helicase subunit of the DNA excision repair complex K03702 uvrB; excinuclease ABC subunit B
E SSU98_0752 Nuclease subunit of the excinuclease complex K03703 uvrC; excinuclease ABC subunit C
E SSU98_0730 Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSU98_0940 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSU98_1393 DNA polymerase I - 3'-5' exonuclease and polymerase domain K02335 polA; DNA polymerase I [EC:2.7.7.7]
E SSU98_1197 NAD-dependent DNA ligase (contains BRCT domain type II) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F SSU98_0122 DNA-directed RNA polymerase, beta subunit/140 kD subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F SSU98_0123 DNA-directed RNA polymerase, beta' subunit/160 kD subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F SSU98_0097 DNA-directed RNA polymerase, alpha subunit/40 kD subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F SSU98_0328 DNA-directed RNA polymerase, delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
F SSU98_0410 DNA-directed RNA polymerase, subunit K/omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F SSU98_0011 Transcription-repair coupling factor (superfamily II helicase) K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E SSU98_2128 Mismatch repair ATPase (MutS family) K03555 mutS; DNA mismatch repair protein MutS
E SSU98_0232 Mismatch repair ATPase (MutS family) K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E SSU98_0060 DNA mismatch repair enzyme (predicted ATPase) K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E SSU98_1666 Exonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E SSU98_1665 Exonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E SSU98_0537 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E SSU98_0536 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E SSU98_1959 DNA polymerase III, alpha subunit (gram-positive type) K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E SSU98_0002 DNA polymerase sliding clamp subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SSU98_0003 DNA polymerase sliding clamp subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SSU98_1551 DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E SSU98_0662 ATPase involved in DNA replication K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E SSU98_1638 DNA polymerase III, gamma/tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E SSU98_1197 NAD-dependent DNA ligase (contains BRCT domain type II) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E SSU98_0730 Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSU98_0940 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSU98_1832 putative single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E SSU98_0147 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E SSU98_0222 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E SSU98_0064 RecA protein K03553 recA; recombination protein RecA
E SSU98_0061 Holliday junction resolvasome, DNA-binding subunit K03550 ruvA; holliday junction DNA helicase RuvA
E SSU98_0049 Holliday junction resolvasome, helicase subunit K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SSU98_0411 Primosomal protein N' (replication factor Y) - superfamily II helicase K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E SSU98_0064 RecA protein K03553 recA; recombination protein RecA
E SSU98_2034 Predicted ATP-dependent serine protease K04485 radA; DNA repair protein RadA/Sms
E SSU98_2180 Recombinational DNA repair ATPase (RecF pathway) K03629 recF; DNA replication and repair protein RecF
E SSU98_0333 RecG-like helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SSU98_1325 Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E SSU98_0026 Recombinational DNA repair protein (RecF pathway) K03584 recO; DNA repair protein RecO (recombination protein O)
E SSU98_1370 Recombinational DNA repair protein (RecF pathway) K06187 recR; recombination protein RecR
E SSU98_1661 ATPase involved in DNA repair K03631 recN; DNA repair protein RecN (Recombination protein N)
E SSU98_0401 Penicillin-binding protein-related factor A, putative recombinase K03700 recU; recombination protein U
E SSU98_0061 Holliday junction resolvasome, DNA-binding subunit K03550 ruvA; holliday junction DNA helicase RuvA
E SSU98_0049 Holliday junction resolvasome, helicase subunit K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E SSU98_0758 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E SSU98_0757 ATP-dependent nuclease, subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E SSU98_0264 conserved hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F SSU98_1086 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F SSU98_1520 DNA gyrase K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SSU98_1521 DNA gyrase B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SSU98_1000 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F SSU98_1657 nucleoid DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F SSU98_1325 Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F SSU98_0026 Recombinational DNA repair protein (RecF pathway) K03584 recO; DNA repair protein RecO (recombination protein O)
F SSU98_1370 Recombinational DNA repair protein (RecF pathway) K06187 recR; recombination protein RecR
F SSU98_1197 NAD-dependent DNA ligase (contains BRCT domain type II) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F SSU98_1828 Excinuclease ATPase subunit K03701 uvrA; excinuclease ABC subunit A
F SSU98_1038 Helicase subunit of the DNA excision repair complex K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D SSU98_0202 Nucleotidyltransferase/DNA polymerase involved in DNA repair K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D SSU98_0064 RecA protein K03553 recA; recombination protein RecA
D SSU98_1661 ATPase involved in DNA repair K03631 recN; DNA repair protein RecN (Recombination protein N)
D SSU98_1832 putative single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SSU98_0147 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SSU98_0430 Uncharacterized protein conserved in bacteria K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D SSU98_0557 Rad3-related DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D SSU98_1033 NTP pyrophosphohydrolase including oxidative damage repair enzymes K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSU98_1161 NTP pyrophosphohydrolase including oxidative damage repair enzymes K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSU98_2008 NTP pyrophosphohydrolase including oxidative damage repair enzymes K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSU98_0485 putative hydrolase (MutT family) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSU98_2164 MutT/NudX family protein (putative) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSU98_1976 unknown protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSU98_2036 dUTPase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SSU98_1222 Ribonucleotide reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SSU98_1224 Ribonucleotide reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D SSU98_1544 hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024