+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Canis lupus familiaris (dog)
%
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 476200 RNMT; mRNA cap guanine-N7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 481914 RNGTT; mRNA-capping enzyme isoform X2 K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 608441 CDK7; cyclin-dependent kinase 7 isoform X1 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 100683999 CMTR1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 isoform X2 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 489718 CMTR2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 479056 RAMAC; RNA guanine-N7 methyltransferase activating subunit K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E 474772 NCBP1; nuclear cap-binding protein subunit 1 isoform X2 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 478603 NCBP2; nuclear cap-binding protein subunit 2 isoform X4 K12883 NCBP2; nuclear cap-binding protein subunit 2
E 100684503 NCBP2L; nuclear cap-binding protein subunit 2-like K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 478123 NUDT21; cleavage and polyadenylation specificity factor subunit 5 isoform X1 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 100684233 cleavage and polyadenylation specificity factor subunit 5-like K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 474441 CPSF6; cleavage and polyadenylation specificity factor subunit 6 isoform X1 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
E 476066 CPSF7; cleavage and polyadenylation specificity factor subunit 7 isoform X1 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 610161 CLP1; polyribonucleotide 5'-hydroxyl-kinase Clp1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E 476786 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 isoform X1 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 475126 CPSF1; cleavage and polyadenylation specificity factor subunit 1 isoform X1 K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E 480230 CPSF2; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 100856414 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X4 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 489859 CPSF4; cleavage and polyadenylation specificity factor subunit 4 isoform X5 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 106559223 CPSF4L; LOW QUALITY PROTEIN: putative cleavage and polyadenylation specificity factor subunit 4-like protein K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 612980 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 isoform X1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 100856093 WDR33; pre-mRNA 3' end processing protein WDR33 isoform X2 K15542 PFS2; polyadenylation factor subunit 2
E 484740 WDR82; WD repeat-containing protein 82 K14962 WDR82; COMPASS component SWD2
E 403557 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 403558 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 403609 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 479567 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
E 608299 RNA polymerase II subunit A C-terminal domain phosphatase SSU72-like K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
E 485220 RNA polymerase II subunit A C-terminal domain phosphatase SSU72-like isoform X1 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 612933 CSTF1; cleavage stimulation factor subunit 1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 119866251 CSTF2T; cleavage stimulation factor subunit 2 tau variant isoform X4 K14407 CSTF2; cleavage stimulation factor subunit 2
E 475948 CSTF3; cleavage stimulation factor subunit 3 isoform X2 K14408 CSTF3; cleavage stimulation factor subunit 3
E 476431 SYMPK; symplekin isoform X1 K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E 485806 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 100684393 LOW QUALITY PROTEIN: small nuclear ribonucleoprotein-associated proteins B and B' K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 607772 SNRPD3; small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 102152884 small nuclear ribonucleoprotein Sm D3-like K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 100855941 SNRPE; small nuclear ribonucleoprotein E isoform X2 K11097 SNRPE; small nuclear ribonucleoprotein E
E 102153759 small nuclear ribonucleoprotein E-like K11097 SNRPE; small nuclear ribonucleoprotein E
E 482609 SNRPF; small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 100687510 small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 100683542 LOW QUALITY PROTEIN: small nuclear ribonucleoprotein F-like K11098 SNRPF; small nuclear ribonucleoprotein F
E 612653 SNRPG; small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
E 111098242 small nuclear ribonucleoprotein G-like K11099 SNRPG; small nuclear ribonucleoprotein G
E 475335 LSM10; U7 snRNA-associated Sm-like protein LSm10 K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E 479314 LSM11; U7 snRNA-associated Sm-like protein LSm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 480230 CPSF2; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 100856414 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X4 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 119866251 CSTF2T; cleavage stimulation factor subunit 2 tau variant isoform X4 K14407 CSTF2; cleavage stimulation factor subunit 2
E 476431 SYMPK; symplekin isoform X1 K06100 SYMPK; symplekin
E 488810 SLBP; histone RNA hairpin-binding protein isoform X2 K18710 SLBP; histone RNA hairpin-binding protein
E 474694 SLBP2; uncharacterized LOC474694 K18710 SLBP; histone RNA hairpin-binding protein
E 481921 CASP8AP2; CASP8-associated protein 2 K25593 CASP8AP2; CASP8-associated protein 2
D DRB sensitivity inducing factor (DSIF) complex
E 609757 SUPT4H1; transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
E 476462 SUPT5H; transcription elongation factor SPT5 isoform X1 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E 475404 METTL3; N6-adenosine-methyltransferase catalytic subunit K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E 487920 METTL14; N6-adenosine-methyltransferase non-catalytic subunit isoform X1 K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 490534 METTL4; N(6)-adenine-specific methyltransferase METTL4 isoform X1 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 480655 METTL16; RNA N6-adenosine-methyltransferase METTL16 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 476259 WTAP; pre-mRNA-splicing regulator WTAP isoform X1 K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 607384 pre-mRNA-splicing regulator WTAP-like K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 477942 VIRMA; protein virilizer homolog isoform X1 K22910 VIRMA; protein virilizer
E 479909 RBM15; RNA-binding protein 15 K13190 RBM15; RNA-binding protein 15
E 100855610 RBM15B; putative RNA-binding protein 15B K13190 RBM15; RNA-binding protein 15
E 485453 ZC3H13; zinc finger CCCH domain-containing protein 13 isoform X4 K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
E 483262 CBLL1; E3 ubiquitin-protein ligase Hakai isoform X2 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 481382 PAPOLG; poly(A) polymerase gamma isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 480430 PAPOLA; poly(A) polymerase alpha isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 106558889 PAPOLB; poly(A) polymerase beta K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 607764 TENT2; poly(A) RNA polymerase GLD2 isoform X1 K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
E 476058 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase isoform X1 K18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]
D Negative regulators of mRNA 3' end processing
E 610190 BARD1; BRCA1-associated RING domain protein 1 isoform X1 K10683 BARD1; BRCA1-associated RING domain protein 1
E 102156002 LOW QUALITY PROTEIN: BRCA1-associated RING domain protein 1-like isoform X3 K10683 BARD1; BRCA1-associated RING domain protein 1
E 476955 RBM26; RNA-binding protein 26 isoform X6 K13192 RBM26; RNA-binding protein 26
E 478125 FTO; alpha-ketoglutarate-dependent dioxygenase FTO isoform X5 K19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 609383 ALKBH5; RNA demethylase ALKBH5 K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 478234 TARDBP; TAR DNA-binding protein 43 isoform X1 K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 480577 DHX40; probable ATP-dependent RNA helicase DHX40 K18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]
D 478010 KIN; DNA/RNA-binding protein KIN17 K13102 KIN; DNA/RNA-binding protein KIN17
D 488397 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 isoform X1 K24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]
D 610231 METTL22; methyltransferase-like protein 22 isoform X3 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 481896 TENT5A; terminal nucleotidyltransferase 5A isoform X3 K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 487348 TENT5B; terminal nucleotidyltransferase 5B K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 483142 TENT5C; terminal nucleotidyltransferase 5C K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D 491983 TENT5D; terminal nucleotidyltransferase 5D K23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
D 480412 ZC3H14; zinc finger CCCH domain-containing protein 14 isoform X2 K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
D 479731 SRRT; serrate RNA effector molecule homolog isoform X4 K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 475827 RBM8A; RNA-binding protein 8A isoform X2 K12876 RBM8A; RNA-binding protein 8A
E 479562 MAGOH; protein mago nashi homolog K12877 MAGOH; protein mago nashi
E 477695 MAGOHB; protein mago nashi homolog 2 K12877 MAGOH; protein mago nashi
E 100684102 protein mago nashi homolog K12877 MAGOH; protein mago nashi
E 607948 ALYREF; THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 474839 DDX39B; spliceosome RNA helicase DDX39B K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E 475922 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 100686384 CCDC174; coiled-coil domain-containing protein 174 isoform X1 K25178 CCDC174; coiled-coil domain-containing protein 174
E 480528 CASC3; protein CASC3 K14323 CASC3; protein CASC3
E 609404 SAP18; histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 403907 PNN; pinin K13114 PNN; pinin
E 480247 ACIN1; apoptotic chromatin condensation inducer in the nucleus isoform X1 K12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus
E 479880 RNPS1; RNA-binding protein with serine-rich domain 1 isoform X1 K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E 478185 SRRM1; serine/arginine repetitive matrix protein 1 isoform X5 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E 490529 THOC1; THO complex subunit 1 K12878 THOC1; THO complex subunit 1
E 481042 THOC2; THO complex subunit 2 isoform X3 K12879 THOC2; THO complex subunit 2
E 607948 ALYREF; THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 477534 THOC5; THO complex subunit 5 homolog isoform X1 K13174 THOC5; THO complex subunit 5
E 479871 THOC6; THO complex subunit 6 homolog K13175 THOC6; THO complex subunit 6
E 102151333 THO complex subunit 6 homolog K13175 THOC6; THO complex subunit 6
E 476567 THOC7; THO complex subunit 7 homolog isoform X1 K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 476994 PCID2; PCI domain-containing protein 2 isoform X2 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 608719 SEM1; 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 475074 ENY2; transcription and mRNA export factor ENY2 isoform X2 K11368 ENY2; enhancer of yellow 2 transcription factor
E 100688271 transcription and mRNA export factor ENY2-like K11368 ENY2; enhancer of yellow 2 transcription factor
E 102151295 transcription and mRNA export factor ENY2-like K11368 ENY2; enhancer of yellow 2 transcription factor
E 481078 CETN2; centrin-2 K10840 CETN2; centrin-2
E 482008 LOW QUALITY PROTEIN: centrin-2-like isoform X1 K10840 CETN2; centrin-2
E 488915 CETN3; centrin-3 isoform X1 K16466 CETN3; centrin-3
E 480810 MCM3AP; germinal-center associated nuclear protein K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D Nuclear pore complex
E 480045 TPR; nucleoprotein TPR isoform X1 K09291 TPR; nucleoprotein TPR
E 485942 RAE1; mRNA export factor isoform X1 K14298 RAE1; mRNA export factor
E 607653 SEC13; protein SEC13 homolog isoform X2 K14004 SEC13; protein transport protein SEC13
E 475445 NUP37; nucleoporin Nup37 K14302 NUP37; nuclear pore complex protein Nup37
E 475913 NUP85; nuclear pore complex protein Nup85 isoform X3 K14304 NUP85; nuclear pore complex protein Nup85
E 484031 NUP43; nucleoporin Nup43 K14305 NUP43; nuclear pore complex protein Nup43
E 474470 NUP50; nuclear pore complex protein Nup50 K14295 NUP50; nuclear pore complex protein Nup50
E 487813 NUP54; nucleoporin p54 isoform X2 K14308 NUP54; nuclear pore complex protein Nup54
E 484370 NUP62; nuclear pore glycoprotein p62 K14306 NUP62; nuclear pore complex protein Nup62
E 610319 NUP62CL; nucleoporin-62 C-terminal-like protein isoform X1 K14306 NUP62; nuclear pore complex protein Nup62
E 607268 NUP88; nuclear pore complex protein Nup88 isoform X1 K14318 NUP88; nuclear pore complex protein Nup88
E 478119 NUP93; nuclear pore complex protein Nup93 isoform X3 K14309 NUP93; nuclear pore complex protein Nup93
E 476822 NUP98; nuclear pore complex protein Nup98-Nup96 isoform X1 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 474440 NUP107; nuclear pore complex protein Nup107 isoform X2 K14301 NUP107; nuclear pore complex protein Nup107
E 479208 NUP133; nuclear pore complex protein Nup133 K14300 NUP133; nuclear pore complex protein Nup133
E 491307 NUP188; nucleoporin NUP188 K14311 NUP188; nuclear pore complex protein Nup188
E 478732 NUP153; nuclear pore complex protein Nup153 isoform X3 K14296 NUP153; nuclear pore complex protein Nup153
E 479360 NUP155; nuclear pore complex protein Nup155 K14312 NUP155; nuclear pore complex protein Nup155
E 483618 NUP160; nuclear pore complex protein Nup160 K14303 NUP160; nuclear pore complex protein Nup160
E 478830 NUP35; nucleoporin NUP35 isoform X2 K14313 NUP35; nuclear pore complex protein Nup53
E 475506 NUP205; nuclear pore complex protein Nup205 isoform X1 K14310 NUP205; nuclear pore complex protein Nup205
E 484632 NUP210; nuclear pore membrane glycoprotein 210 isoform X1 K14314 NUP210; nuclear pore complex protein Nup210
E 490448 NUP210L; nuclear pore membrane glycoprotein 210-like isoform X4 K14314 NUP210; nuclear pore complex protein Nup210
E 608534 NUP214; nuclear pore complex protein Nup214 isoform X6 K14317 NUP214; nuclear pore complex protein Nup214
E 489812 POM121C; nuclear envelope pore membrane protein POM 121C isoform X1 K14316 POM121; nuclear pore complex protein Nup121
E 611386 LOW QUALITY PROTEIN: POM121-like protein 2 isoform X3 K14316 POM121; nuclear pore complex protein Nup121
E 111095750 putative POM121-like protein 1-like K14316 POM121; nuclear pore complex protein Nup121
E 477334 NUP58; nucleoporin p58/p45 isoform X2 K14307 NUPL1; nucleoporin p58/p45
E 100855902 NUP42; nucleoporin NUP42 isoform X1 K14321 NUPL2; nucleoporin-like protein 2
E 100684187 NDC1; nucleoporin NDC1 isoform X3 K14315 NDC1; nucleoporin NDC1
E 490564 SEH1L; nucleoporin SEH1 isoform X1 K14299 SEH1; nucleoporin SEH1
E 474539 RANBP2; E3 SUMO-protein ligase RanBP2 isoform X1 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E 478661 SENP2; sentrin-specific protease 2 isoform X4 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
E 607867 AAAS; aladin isoform X2 K14320 AAAS; aladin
E 488915 CETN3; centrin-3 isoform X1 K16466 CETN3; centrin-3
E 480704 GLE1; nucleoporin GLE1 isoform X1 K18723 GLE1; nucleoporin GLE1
E 483780 NXF1; nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 492024 nuclear RNA export factor 2-like isoform X27 K14284 NXF; nuclear RNA export factor
E 491441 NXF3; nuclear RNA export factor 3 isoform X7 K14284 NXF; nuclear RNA export factor
E 100687327 LOW QUALITY PROTEIN: nuclear RNA export factor 2-like isoform X5 K14284 NXF; nuclear RNA export factor
E 477132 NXT1; NTF2-related export protein 1 K14285 NXT1_2; NTF2-related export protein 1/2
E 612945 NXT2; NTF2-related export protein 2 isoform X1 K14285 NXT1_2; NTF2-related export protein 1/2
E 102151355 nuclear pore-associated protein 1-like isoform X3 K26564 NPAP1; nuclear pore-associated protein 1
D Ran-mediated transport factors
E 100499482 RAN; GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
E 403534 ANP32A; acidic leucine-rich nuclear phosphoprotein 32 family member A K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 474775 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1 K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 100568281 TNFSF13; tumor necrosis factor ligand superfamily member 13 K05475 TNFSF13; tumor necrosis factor ligand superfamily member 13
E 611201 ELAVL1; ELAV-like protein 1 K13088 ELAVL1; ELAV-like protein 1
E 480466 ELAV-like protein 1 K13088 ELAVL1; ELAV-like protein 1
E 481565 ELAVL2; ELAV-like protein 2 isoform X3 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 484940 ELAVL3; ELAV-like protein 3 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 475361 ELAVL4; ELAV-like protein 4 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 489102 FAF2; FAS-associated factor 2 isoform X2 K18726 FAF2; FAS-associated factor 2
E 481590 VCP; transitional endoplasmic reticulum ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
E 609034 VCPKMT; protein-lysine methyltransferase METTL21D isoform X2 K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 484930 TNPO2; transportin-2 isoform X1 K18727 TNPO2; transportin-2
E 474609 XPO1; exportin-1 isoform X1 K14290 XPO1; exportin-1
E 477387 XPO7; exportin-7 isoform X1 K18460 XPO7; exportin-7
E 479293 RANBP17; ran-binding protein 17 isoform X1 K24115 RANBP17; Ran-binding protein 17
E 481234 RANGAP1; ran GTPase-activating protein 1 isoform X1 K14319 RANGAP1; Ran GTPase-activating protein 1
E 491135 TAF15; TATA-binding protein-associated factor 2N K14651 TAF15; transcription initiation factor TFIID subunit 15
D eIF4F and regulatory proteins
E 487870 EIF4E; eukaryotic translation initiation factor 4E isoform X1 K03259 EIF4E; translation initiation factor 4E
E 610238 EIF4E2; eukaryotic translation initiation factor 4E type 2 K03259 EIF4E; translation initiation factor 4E
E 489099 EIF4E1B; eukaryotic translation initiation factor 4E type 1B isoform X1 K03259 EIF4E; translation initiation factor 4E
E 611215 LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4E type 2-like K03259 EIF4E; translation initiation factor 4E
E 100685582 eukaryotic translation initiation factor 4E type 2-like K03259 EIF4E; translation initiation factor 4E
E 488118 EIF4A2; eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 100688577 EIF4A1; eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 478202 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 100688785 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 100855511 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 477600 EIF4B; eukaryotic translation initiation factor 4B isoform X1 K03258 EIF4B; translation initiation factor 4B
E 607749 EIF4H; eukaryotic translation initiation factor 4H isoform X1 K24086 EIF4H; translation initiation factor 4H
E 475590 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1 K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
E 489027 EIF4EBP2; eukaryotic translation initiation factor 4E-binding protein 2 K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E 100529255 EIF4EBP3; eukaryotic translation initiation factor 4E-binding protein 3 K18645 EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3
E 486366 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X3 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 490287 ANGEL2; protein angel homolog 2 isoform X2 K18729 ANGEL; protein angel
E 490800 ANGEL1; protein angel homolog 1 isoform X2 K18729 ANGEL; protein angel
E 481070 FMR1; synaptic functional regulator FMR1 isoform X2 K15516 FMR; fragile X mental retardation protein
E 489478 FXR2; fragile X mental retardation syndrome-related protein 2 isoform X4 K15516 FMR; fragile X mental retardation protein
E 100855907 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X4 K15516 FMR; fragile X mental retardation protein
E 479001 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 479317 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 479321 GEMIN5; gem-associated protein 5 isoform X1 K13133 GEMIN5; gem associated protein 5
E 479079 TACC3; transforming acidic coiled-coil-containing protein 3 isoform X1 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 100683974 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 479287 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X17 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 486801 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 488821 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X40 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 480886 DDX3X; ATP-dependent RNA helicase DDX3X isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 489833 GIGYF1; GRB10-interacting GYF protein 1 isoform X4 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 612838 GIGYF2; GRB10-interacting GYF protein 2 isoform X2 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 612751 PABPC1; polyadenylate-binding protein 1 isoform X2 K13126 PABPC; polyadenylate-binding protein
E 492002 PABPC5; polyadenylate-binding protein 5 K13126 PABPC; polyadenylate-binding protein
E 482464 PABPC4; polyadenylate-binding protein 4 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 477238 PABPC1L; polyadenylate-binding protein 1-like isoform X2 K13126 PABPC; polyadenylate-binding protein
E 483825 PABPC4L; polyadenylate-binding protein 4-like K13126 PABPC; polyadenylate-binding protein
E 119868207 PABPC1L2A; polyadenylate-binding protein 1-like 2 K13126 PABPC; polyadenylate-binding protein
E 479343 PAIP1; polyadenylate-binding protein-interacting protein 1 isoform X4 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 478024 PAIP2; polyadenylate-binding protein-interacting protein 2 K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 481720 SKIV2L; helicase SKI2W K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 483409 DEAF1; deformed epidermal autoregulatory factor 1 homolog isoform X1 K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 487150 malignant T-cell-amplified sequence 1-like K07575 MCTS; malignant T-cell-amplified sequence
E 481038 MCTS1; malignant T-cell-amplified sequence 1 isoform X2 K07575 MCTS; malignant T-cell-amplified sequence
E 610709 DENR; density-regulated protein isoform X1 K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
E 486699 APOBEC1; C->U-editing enzyme APOBEC-1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 477581 A1CF; APOBEC1 complementation factor isoform X1 K24978 A1CF; APOBEC1 complementation factor
D Other transport factors
E 481101 PYM1; partner of Y14 and mago K14294 WIBG; partner of Y14 and mago
E 608074 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 608729 heterogeneous nuclear ribonucleoprotein A1-like isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102152026 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102156730 heterogeneous nuclear ribonucleoprotein A1-like isoform X3 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102151489 heterogeneous nuclear ribonucleoprotein A3-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 119866566 heterogeneous nuclear ribonucleoprotein A3 isoform X8 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 119870156 LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 119874304 heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 119881680 heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 608117 heterogeneous nuclear ribonucleoprotein A1-like isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 610488 heterogeneous nuclear ribonucleoprotein A3-like isoform X3 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 611488 MSI1; RNA-binding protein Musashi homolog 1 isoform X2 K14411 MSI; RNA-binding protein Musashi
E 475148 MSI2; RNA-binding protein Musashi homolog 2 isoform X53 K14411 MSI; RNA-binding protein Musashi
E 100683271 DAZAP1; DAZ-associated protein 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 102156482 RNA-binding protein Musashi homolog 2 K14411 MSI; RNA-binding protein Musashi
E 476211 HBS1L; HBS1-like protein isoform X4 K14416 HBS1; elongation factor 1 alpha-like protein
E 479338 PELO; protein pelota homolog K06965 PELO; protein pelota
E 608851 PABPN1L; LOW QUALITY PROTEIN: embryonic polyadenylate-binding protein 2 K14396 PABPN1; polyadenylate-binding protein 2
E 100170671 PABPN1; polyadenylate-binding protein 2 K14396 PABPN1; polyadenylate-binding protein 2
E 479657 DDX19B; ATP-dependent RNA helicase DDX19B isoform X2 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 479658 DDX19A; ATP-dependent RNA helicase DDX19A isoform X2 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 479396 DDX25; ATP-dependent RNA helicase DDX25 isoform X1 K18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]
E 484995 XAB2; pre-mRNA-splicing factor SYF1 K12867 SYF1; pre-mRNA-splicing factor SYF1
E 474392 SARNP; SAP domain-containing ribonucleoprotein K18732 SARNP; SAP domain-containing ribonucleoprotein
E 487332 RCC1; regulator of chromosome condensation K11493 RCC1; regulator of chromosome condensation
E 487625 LARP6; la-related protein 6 K18733 LARP6; la-related protein 6
E 487159 PURA; transcriptional activator protein Pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha
E 106558494 PURB; transcriptional activator protein Pur-beta K21799 PURB; transcriptional activator protein Pur-beta
E 474480 POLDIP3; polymerase delta-interacting protein 3 isoform X2 K22414 POLDIP3; polymerase delta-interacting protein 3
E 478932 ZC3H11A; zinc finger CCCH domain-containing protein 11A isoform X1 K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 476385 LENG8; leukocyte receptor cluster member 8 isoform X5 K23802 LENG8; SAC3 family protein LENG8/THP3
E 100856734 PATL2; protein PAT1 homolog 2 K24823 PATL2; protein PAT1 homolog 2
C Surveillance factors
D Surveillance complex
E 608717 ETF1; eukaryotic peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
E 479846 GSPT1; LOW QUALITY PROTEIN: eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X1 K03267 ERF3; peptide chain release factor subunit 3
E 476664 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 487130 UPF2; regulator of nonsense transcripts 2 isoform X3 K14327 UPF2; regulator of nonsense transcripts 2
E 607836 UPF3A; regulator of nonsense transcripts 3A isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 481031 UPF3B; regulator of nonsense transcripts 3B isoform X14 K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E 403608 PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 482873 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 484335 PPP2R1A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1 K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 479444 PPP2R1B; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1 K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 477374 PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X6 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 610262 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform X2 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 491587 PPP2R2D; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X2 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 478053 PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X2 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 480289 PPP2R3C; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X2 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 485672 PPP2R3A; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 100855509 PPP2R3B; LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 483755 PPP2R5B; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform isoform X2 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 480436 PPP2R5C; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X2 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 481806 PPP2R5D; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 480349 PPP2R5E; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X3 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 490280 PPP2R5A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 479832 SMG1; serine/threonine-protein kinase SMG1 isoform X1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 490414 SMG5; protein SMG5 isoform X8 K11125 SMG5; protein SMG5
E 491199 SMG6; telomerase-binding protein EST1A isoform X2 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 480035 SMG7; protein SMG7 isoform X2 K14409 SMG7; protein SMG7
E 491116 SMG8; protein SMG8 K18734 SMG8; protein SMG8
E 476444 SMG9; protein SMG9 isoform X4 K18735 SMG9; protein SMG9
E 489833 GIGYF1; GRB10-interacting GYF protein 1 isoform X4 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 612838 GIGYF2; GRB10-interacting GYF protein 2 isoform X2 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 476351 SECISBP2; selenocysteine insertion sequence-binding protein 2 isoform X20 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 487547 SECISBP2L; selenocysteine insertion sequence-binding protein 2-like K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 484422 DHX34; probable ATP-dependent RNA helicase DHX34 isoform X4 K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
E 474506 GTPBP1; GTP-binding protein 1 isoform X4 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 476337 PUM3; pumilio homolog 3 K14844 PUF6; pumilio homology domain family member 6
E 478312 MYO5A; unconventional myosin-Va isoform X1 K10357 MYO5; myosin V
E 480220 MYO5B; unconventional myosin-Vb K10357 MYO5; myosin V
E 487555 MYO5C; unconventional myosin-Vc K10357 MYO5; myosin V
E 484214 BICD2; protein bicaudal D homolog 2 isoform X2 K18739 BICD; protein bicaudal D
E 610028 BICD1; protein bicaudal D homolog 1 isoform X1 K18739 BICD; protein bicaudal D
E 478263 EXD1; piRNA biogenesis protein EXD1 isoform X1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
E 403580 ACTB; actin, cytoplasmic 1 K05692 ACTB_G1; actin beta/gamma 1
E 475923 ACTG1; actin, cytoplasmic 2 K05692 ACTB_G1; actin beta/gamma 1
E 476160 MBP; myelin basic protein isoform X1 K17269 MBP; myelin basic protein
E 477991 VIM; vimentin K07606 VIM; vimentin
E 607206 LOW QUALITY PROTEIN: vimentin-like isoform X1 K07606 VIM; vimentin
E 403768 MT2A; metallothionein-2 K14739 MT1_2; metallothionein 1/2
E 403800 MT1E; metallothionein-1 K14739 MT1_2; metallothionein 1/2
E 100686073 metallothionein-1 K14739 MT1_2; metallothionein 1/2
E 403924 MYC; myc proto-oncogene protein K04377 MYC; Myc proto-oncogene protein
E 100686938 GDF1; embryonic growth/differentiation factor 1 K05495 GDF1; growth differentiation factor 1
E 489948 TBX6; T-box transcription factor TBX6 K10180 TBX6; T-box protein 6
E 100683604 NANOS1; LOW QUALITY PROTEIN: nanos homolog 1 K18741 NANOS1; protein nanos 1
D Trans-acting binding proteins
E 611825 ZBP1; Z-DNA-binding protein 1 isoform X1 K12965 ZBP1; Z-DNA binding protein 1
E 485022 KHSRP; far upstream element-binding protein 2 isoform X1 K13210 FUBP; far upstream element-binding protein
E 608171 FUBP3; far upstream element-binding protein 3 isoform X1 K13210 FUBP; far upstream element-binding protein
E 100855608 FUBP1; far upstream element-binding protein 1 isoform X10 K13210 FUBP; far upstream element-binding protein
E 403506 EEF1A1; elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
E 612521 EEF1A2; elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 102153873 putative elongation factor 1-alpha-like 3 K03231 EEF1A; elongation factor 1-alpha
E 100685794 elongation factor 1-alpha 1-like K03231 EEF1A; elongation factor 1-alpha
E 485131 elongation factor 1-alpha 2-like isoform X2 K03231 EEF1A; elongation factor 1-alpha
E 487375 elongation factor 1-alpha 1-like K03231 EEF1A; elongation factor 1-alpha
E 106559713 elongation factor 1-alpha 1-like K03231 EEF1A; elongation factor 1-alpha
E 111096123 LOW QUALITY PROTEIN: elongation factor 1-alpha 1-like K03231 EEF1A; elongation factor 1-alpha
E 611396 EEF1G; elongation factor 1-gamma K03233 EEF1G; elongation factor 1-gamma
E 475260 HNRNPA2B1; heterogeneous nuclear ribonucleoproteins A2/B1 isoform X1 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 480134 HAX1; HCLS1-associated protein X-1 isoform X2 K16220 HAX1; HCLS1-associated protein X-1
E 477396 AGFG1; arf-GAP domain and FG repeat-containing protein 1 isoform X7 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 477258 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X8 K17597 STAU; double-stranded RNA-binding protein Staufen
E 477913 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X5 K17597 STAU; double-stranded RNA-binding protein Staufen
E 482357 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3 K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
E 485097 PTBP1; polypyrimidine tract-binding protein 1 isoform X3 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 100683974 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 479287 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X17 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 486801 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 488821 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X40 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 481070 FMR1; synaptic functional regulator FMR1 isoform X2 K15516 FMR; fragile X mental retardation protein
E 489478 FXR2; fragile X mental retardation syndrome-related protein 2 isoform X4 K15516 FMR; fragile X mental retardation protein
E 100855907 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X4 K15516 FMR; fragile X mental retardation protein
E 479001 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 479317 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 477596 PCBP2; poly(rC)-binding protein 2 isoform X1 K13162 PCBP2; poly(rC)-binding protein 2
E 100856028 LOW QUALITY PROTEIN: poly(rC)-binding protein 2-like K13162 PCBP2; poly(rC)-binding protein 2
E 607066 PCBP3; poly(rC)-binding protein 3 isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 476603 PCBP4; poly(rC)-binding protein 4 isoform X2 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 607420 CAPRIN1; caprin-1 K18743 CAPRIN1; caprin-1
E 477653 CAPRIN2; caprin-2 isoform X1 K18744 CAPRIN2; caprin-2
E 479011 Y-box-binding protein 1 K09276 YBX1; Y-box-binding protein 1
E 607025 YBX1; Y-box-binding protein 1 isoform X2 K09276 YBX1; Y-box-binding protein 1
E 474472 Y-box-binding protein 1-like K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 477100 XRN1; 5'-3' exoribonuclease 1 isoform X4 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 475336 AGO3; protein argonaute-3 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 475337 AGO1; protein argonaute-1 isoform X3 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 482480 AGO4; protein argonaute-4 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 475107 AGO2; protein argonaute-2 isoform X3 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 487870 EIF4E; eukaryotic translation initiation factor 4E isoform X1 K03259 EIF4E; translation initiation factor 4E
E 610238 EIF4E2; eukaryotic translation initiation factor 4E type 2 K03259 EIF4E; translation initiation factor 4E
E 489099 EIF4E1B; eukaryotic translation initiation factor 4E type 1B isoform X1 K03259 EIF4E; translation initiation factor 4E
E 611215 LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4E type 2-like K03259 EIF4E; translation initiation factor 4E
E 100685582 eukaryotic translation initiation factor 4E type 2-like K03259 EIF4E; translation initiation factor 4E
E 476664 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 480886 DDX3X; ATP-dependent RNA helicase DDX3X isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 479414 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 479071 LOW QUALITY PROTEIN: probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 476195 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C isoform X4 K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 490417 MEX3A; RNA-binding protein MEX3A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 612270 MEX3D; RNA-binding protein MEX3D isoform X1 K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 100855735 MEX3B; RNA-binding protein MEX3B isoform X2 K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 482802 FASTK; fas-activated serine/threonine kinase K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
E 476492 LSM14A; protein LSM14 homolog A isoform X3 K18749 LSM14; protein LSM14
E 485957 LSM14B; protein LSM14 homolog B isoform X7 K18749 LSM14; protein LSM14
E 481417 PCBP1; poly(rC)-binding protein 1 K12889 PCBP1; poly(rC)-binding protein 1
E 491817 LOW QUALITY PROTEIN: poly(rC)-binding protein 1-like K12889 PCBP1; poly(rC)-binding protein 1
E 477596 PCBP2; poly(rC)-binding protein 2 isoform X1 K13162 PCBP2; poly(rC)-binding protein 2
E 100856028 LOW QUALITY PROTEIN: poly(rC)-binding protein 2-like K13162 PCBP2; poly(rC)-binding protein 2
E 479011 Y-box-binding protein 1 K09276 YBX1; Y-box-binding protein 1
E 607025 YBX1; Y-box-binding protein 1 isoform X2 K09276 YBX1; Y-box-binding protein 1
E 474472 Y-box-binding protein 1-like K09276 YBX1; Y-box-binding protein 1
E 480244 AJUBA; LIM domain-containing protein ajuba isoform X1 K16682 AJUBA; LIM domain-containing protein
E 100683350 WTIP; Wilms tumor protein 1-interacting protein isoform X2 K16682 AJUBA; LIM domain-containing protein
E 100856566 LIMD1; LIM domain-containing protein 1 isoform X5 K16682 AJUBA; LIM domain-containing protein
E 486699 APOBEC1; C->U-editing enzyme APOBEC-1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 610245 APOBEC3Z1; LOW QUALITY PROTEIN: apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3Z1 isoform X1 K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 481248 APOBEC3Z3; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3Z3 K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 483219 MOV10; helicase MOV-10 isoform X4 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 100855478 PNRC2; proline-rich nuclear receptor coactivator 2 K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 100684639 proline-rich nuclear receptor coactivator 2-like K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 478093 TNPO1; transportin-1 isoform X1 K18752 TNPO1; transportin-1
E 479832 SMG1; serine/threonine-protein kinase SMG1 isoform X1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 490414 SMG5; protein SMG5 isoform X8 K11125 SMG5; protein SMG5
E 491199 SMG6; telomerase-binding protein EST1A isoform X2 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 480035 SMG7; protein SMG7 isoform X2 K14409 SMG7; protein SMG7
E 484510 ZFP36; mRNA decay activator protein ZFP36 K15308 TTP; tristetraprolin
E 100856710 ZFP36L2; mRNA decay activator protein ZFP36L2 K18753 ZFP36L; butyrate response factor
E 490748 ZFP36L1; mRNA decay activator protein ZFP36L1 K18753 ZFP36L; butyrate response factor
E 481943 LIN28B; protein lin-28 homolog B isoform X1 K18754 LIN28; protein lin-28
E 479074 HTT; huntingtin isoform X2 K04533 HD; huntingtin
E 612863 IPO8; importin-8 isoform X1 K18755 IPO8; importin-8
E 608626 BICC1; protein bicaudal C homolog 1 isoform X2 K18756 BICC1; protein bicaudal C
E 608074 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 608729 heterogeneous nuclear ribonucleoprotein A1-like isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102152026 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102156730 heterogeneous nuclear ribonucleoprotein A1-like isoform X3 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102151489 heterogeneous nuclear ribonucleoprotein A3-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 119866566 heterogeneous nuclear ribonucleoprotein A3 isoform X8 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 119870156 LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 119874304 heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 119881680 heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 608117 heterogeneous nuclear ribonucleoprotein A1-like isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 610488 heterogeneous nuclear ribonucleoprotein A3-like isoform X3 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 403556 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha K04345 PKA; protein kinase A [EC:2.7.11.11]
E 479975 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X2 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 612929 LARP1; la-related protein 1 isoform X2 K18757 LARP1; la-related protein 1
E 476085 LARP1B; la-related protein 1B isoform X1 K18757 LARP1; la-related protein 1
E 486270 ATXN2; ataxin-2 isoform X1 K23625 ATXN2_2L; ataxin 2/2L
E 489951 ATXN2L; ataxin-2-like protein isoform X3 K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 489086 DCP2; m7GpppN-mRNA hydrolase K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 607346 DCP1A; mRNA-decapping enzyme 1A isoform X2 K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 477734 DCP1B; mRNA-decapping enzyme 1B isoform X2 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 475587 LSM1; U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 474849 LSM2; U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 102154474 U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 607248 LSM3; U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 102154080 U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 102154724 U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 119865916 U6 snRNA-associated Sm-like protein LSm3 isoform X3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 609922 LSM4; U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 611686 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 612329 LSM6; U6 snRNA-associated Sm-like protein LSm6 isoform X1 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 612170 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 475298 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 474909 KLC4; kinesin light chain 4 K10407 KLC; kinesin light chain
E 483715 KLC2; kinesin light chain 2 K10407 KLC; kinesin light chain
E 484448 KLC3; kinesin light chain 3 isoform X1 K10407 KLC; kinesin light chain
E 100855591 KLC1; kinesin light chain 1 isoform X10 K10407 KLC; kinesin light chain
E 478312 MYO5A; unconventional myosin-Va isoform X1 K10357 MYO5; myosin V
E 480220 MYO5B; unconventional myosin-Vb K10357 MYO5; myosin V
E 487555 MYO5C; unconventional myosin-Vc K10357 MYO5; myosin V
E 478918 TUBA4A; tubulin alpha-4A chain isoform X2 K07374 TUBA; tubulin alpha
E 486762 TUBA8; tubulin alpha-8 chain isoform X12 K07374 TUBA; tubulin alpha
E 608051 tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 477570 tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 487148 TUBAL3; tubulin alpha chain-like 3 K07374 TUBA; tubulin alpha
E 610636 tubulin alpha-1B chain isoform X2 K07374 TUBA; tubulin alpha
E 100856405 TUBA1C; tubulin alpha-1C chain K07374 TUBA; tubulin alpha
E 106557476 tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 100855995 tubulin alpha-8 chain-like isoform X3 K07374 TUBA; tubulin alpha
E 119866377 tubulin alpha-1B chain K07374 TUBA; tubulin alpha
E 100683974 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 479287 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X17 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 486801 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 488821 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X40 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 479321 GEMIN5; gem-associated protein 5 isoform X1 K13133 GEMIN5; gem associated protein 5
E 479079 TACC3; transforming acidic coiled-coil-containing protein 3 isoform X1 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 489966 TNRC6A; trinucleotide repeat-containing gene 6A protein isoform X10 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 481240 TNRC6B; trinucleotide repeat-containing gene 6B protein isoform X7 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 483340 TNRC6C; trinucleotide repeat-containing gene 6C protein isoform X2 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 608777 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 474446 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X22 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 484312 CNOT3; CCR4-NOT transcription complex subunit 3 isoform X1 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 482708 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 481463 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X3 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 487817 CNOT6L; CCR4-NOT transcription complex subunit 6-like isoform X2 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 482895 CNOT7; CCR4-NOT transcription complex subunit 7 isoform X2 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 489162 CNOT8; CCR4-NOT transcription complex subunit 8 isoform X1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 612685 GARRE1; granule associated Rac and RHOG effector protein 1 isoform X1 K26671 GARRE1; granule associated Rac and RHOG effector protein 1
E 610194 DIS3L2; DIS3-like exonuclease 2 isoform X1 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 474404 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 486024 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 481233 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 487695 BTG3; protein BTG3 K14443 TOB; protein Tob/BTG
E 488559 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 100684605 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 111089952 BTG4; protein BTG4 isoform X1 K14443 TOB; protein Tob/BTG
E 486366 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X3 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 609696 PATL1; protein PAT1 homolog 1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 487647 EDC3; enhancer of mRNA-decapping protein 3 isoform X2 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 489751 EDC4; enhancer of mRNA-decapping protein 4 isoform X2 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 484432 NANOS2; nanos homolog 2 K18760 NANOS2; protein nanos 2
E 119864731 NANOS3; nanos homolog 3 K18761 NANOS3; protein nanos 3
E 487130 UPF2; regulator of nonsense transcripts 2 isoform X3 K14327 UPF2; regulator of nonsense transcripts 2
E 607836 UPF3A; regulator of nonsense transcripts 3A isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 481031 UPF3B; regulator of nonsense transcripts 3B isoform X14 K14328 UPF3; regulator of nonsense transcripts 3
E 485226 TRIM21; E3 ubiquitin-protein ligase TRIM21 K10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]
E 477014 TRIM71; E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 476052 POLR2G; DNA-directed RNA polymerase II subunit RPB7 isoform X2 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 611397 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
E 100688284 ZAR1; zygote arrest protein 1 isoform X5 K18762 ZAR1; zygote arrest protein 1
E 477317 ZAR1L; ZAR1-like protein isoform X1 K18762 ZAR1; zygote arrest protein 1
E 478161 YTHDF2; YTH domain-containing family protein 2 isoform X1 K20102 YTHDF; YTH domain-containing family protein
E 485968 YTHDF1; YTH domain-containing family protein 1 isoform X2 K20102 YTHDF; YTH domain-containing family protein
E 486970 YTHDF3; YTH domain-containing family protein 3 isoform X1 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 477841 TIAL1; nucleolysin TIAR isoform X4 K13201 TIA1; nucleolysin TIA-1/TIAR
E 610625 TIA1; nucleolysin TIA-1 isoform X3 K13201 TIA1; nucleolysin TIA-1/TIAR
E 612751 PABPC1; polyadenylate-binding protein 1 isoform X2 K13126 PABPC; polyadenylate-binding protein
E 492002 PABPC5; polyadenylate-binding protein 5 K13126 PABPC; polyadenylate-binding protein
E 482464 PABPC4; polyadenylate-binding protein 4 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 477238 PABPC1L; polyadenylate-binding protein 1-like isoform X2 K13126 PABPC; polyadenylate-binding protein
E 483825 PABPC4L; polyadenylate-binding protein 4-like K13126 PABPC; polyadenylate-binding protein
E 119868207 PABPC1L2A; polyadenylate-binding protein 1-like 2 K13126 PABPC; polyadenylate-binding protein
E 477258 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X8 K17597 STAU; double-stranded RNA-binding protein Staufen
E 477913 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X5 K17597 STAU; double-stranded RNA-binding protein Staufen
E 481070 FMR1; synaptic functional regulator FMR1 isoform X2 K15516 FMR; fragile X mental retardation protein
E 489478 FXR2; fragile X mental retardation syndrome-related protein 2 isoform X4 K15516 FMR; fragile X mental retardation protein
E 100855907 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X4 K15516 FMR; fragile X mental retardation protein
E 611825 ZBP1; Z-DNA-binding protein 1 isoform X1 K12965 ZBP1; Z-DNA binding protein 1
E 611201 ELAVL1; ELAV-like protein 1 K13088 ELAVL1; ELAV-like protein 1
E 480466 ELAV-like protein 1 K13088 ELAVL1; ELAV-like protein 1
E 479322 G3BP1; ras GTPase-activating protein-binding protein 1 K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
E 478429 G3BP2; ras GTPase-activating protein-binding protein 2 isoform X1 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 477112 EIF2A; eukaryotic translation initiation factor 2A K15026 EIF2A; translation initiation factor 2A
E 479766 EIF3B; eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E 488118 EIF4A2; eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 100688577 EIF4A1; eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 475922 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 477600 EIF4B; eukaryotic translation initiation factor 4B isoform X1 K03258 EIF4B; translation initiation factor 4B
E 478202 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 100688785 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 100855511 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 487353 RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform X2 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 612448 RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 491989 RPS6KA6; ribosomal protein S6 kinase alpha-6 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 480818 RACK1; receptor of activated protein C kinase 1 K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 480673 TRAF2; TNF receptor-associated factor 2 isoform X2 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 483780 NXF1; nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 492024 nuclear RNA export factor 2-like isoform X27 K14284 NXF; nuclear RNA export factor
E 491441 NXF3; nuclear RNA export factor 3 isoform X7 K14284 NXF; nuclear RNA export factor
E 100687327 LOW QUALITY PROTEIN: nuclear RNA export factor 2-like isoform X5 K14284 NXF; nuclear RNA export factor
E 480907 HDAC6; histone deacetylase 6 isoform X4 K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
E 100686460 TDRD3; tudor domain-containing protein 3 isoform X1 K18404 TDRD3; tudor domain-containing protein 3
E 491346 LOW QUALITY PROTEIN: tudor domain-containing protein 3 isoform X1 K18404 TDRD3; tudor domain-containing protein 3
E 477609 LARP4; la-related protein 4 isoform X3 K18763 LARP4; la-related protein 4
E 478022 LARP4B; la-related protein 4B isoform X1 K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 607346 DCP1A; mRNA-decapping enzyme 1A isoform X2 K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 477734 DCP1B; mRNA-decapping enzyme 1B isoform X2 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 489086 DCP2; m7GpppN-mRNA hydrolase K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 479414 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 479071 LOW QUALITY PROTEIN: probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 487647 EDC3; enhancer of mRNA-decapping protein 3 isoform X2 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 489751 EDC4; enhancer of mRNA-decapping protein 4 isoform X2 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 609696 PATL1; protein PAT1 homolog 1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 475587 LSM1; U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 474849 LSM2; U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 102154474 U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 607248 LSM3; U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 102154080 U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 102154724 U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 119865916 U6 snRNA-associated Sm-like protein LSm3 isoform X3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 609922 LSM4; U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 611686 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 612329 LSM6; U6 snRNA-associated Sm-like protein LSm6 isoform X1 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 612170 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 475298 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 477100 XRN1; 5'-3' exoribonuclease 1 isoform X4 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 477133 XRN2; 5'-3' exoribonuclease 2 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
E 610721 NUDT16; U8 snoRNA-decapping enzyme K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
D Other 5'-3' decay factors
E 609536 DCPS; m7GpppX diphosphatase isoform X2 K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 490907 HELZ; probable helicase with zinc finger domain isoform X1 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E 477787 EXOSC1; exosome complex component CSL4 isoform X2 K07573 CSL4; exosome complex component CSL4
E 608606 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 481616 EXOSC3; exosome complex component RRP40 K03681 RRP40; exosome complex component RRP40
E 482086 EXOSC4; exosome complex component RRP41 isoform X2 K11600 RRP41; exosome complex component RRP41
E 611350 EXOSC5; exosome complex component RRP46 K12590 RRP46; exosome complex component RRP46
E 489713 EXOSC6; exosome complex component MTR3 K12587 MTR3; exosome complex component MTR3
E 476654 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
E 477300 EXOSC8; exosome complex component RRP43 isoform X1 K12586 RRP43; exosome complex component RRP43
E 476093 EXOSC9; exosome complex component RRP45 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 485491 DIS3; exosome complex exonuclease RRP44 isoform X3 K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 478346 DIS3L; DIS3-like exonuclease 1 isoform X1 K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E 478233 EXOSC10; exosome component 10 isoform X2 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 612549 C1D; nuclear nucleic acid-binding protein C1D K12592 C1D; exosome complex protein LRP1
E 479632 MPHOSPH6; M-phase phosphoprotein 6 isoform X2 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
E 111093384 M-phase phosphoprotein 6-like isoform X1 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
E 475493 DDX60; probable ATP-dependent RNA helicase DDX60 isoform X1 K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
D TRAMP complex
E 488057 TENT4A; terminal nucleotidyltransferase 4A isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 478131 TENT4B; terminal nucleotidyltransferase 4B isoform X2 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 481611 ZCCHC7; zinc finger CCHC domain-containing protein 7 K12597 AIR1_2; protein AIR1/2
E 607950 MTREX; exosome RNA helicase MTR4 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 481720 SKIV2L; helicase SKI2W K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 479150 TTC37; tetratricopeptide repeat protein 37 K12600 SKI3; superkiller protein 3
E 479068 WDR61; WD repeat-containing protein 61 K12602 WDR61; WD repeat-containing protein 61
E 100687895 LOW QUALITY PROTEIN: WD repeat-containing protein 61-like K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 481463 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X3 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 487817 CNOT6L; CCR4-NOT transcription complex subunit 6-like isoform X2 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 608777 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 474446 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X22 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 484312 CNOT3; CCR4-NOT transcription complex subunit 3 isoform X1 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 482708 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 482895 CNOT7; CCR4-NOT transcription complex subunit 7 isoform X2 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 489162 CNOT8; CCR4-NOT transcription complex subunit 8 isoform X1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 610449 CNOT9; CCR4-NOT transcription complex subunit 9 isoform X2 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 612778 CNOT10; CCR4-NOT transcription complex subunit 10 isoform X2 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 474404 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 486024 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 479839 PARN; poly(A)-specific ribonuclease PARN isoform X5 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 484065 PNLDC1; poly(A)-specific ribonuclease PNLDC1 isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 477117 DHX36; ATP-dependent DNA/RNA helicase DHX36 isoform X1 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 481233 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 487695 BTG3; protein BTG3 K14443 TOB; protein Tob/BTG
E 488559 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 100684605 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 111089952 BTG4; protein BTG4 isoform X1 K14443 TOB; protein Tob/BTG
E 403923 CSF2; granulocyte-macrophage colony-stimulating factor precursor K05427 CSF2; granulocyte-macrophage colony-stimulating factor
E 483818 NOCT; nocturnin isoform X3 K18764 NOCT; nocturnin [EC:3.1.3.108]
E 608878 ERI2; ERI1 exoribonuclease 2 isoform X2 K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
E 609536 DCPS; m7GpppX diphosphatase isoform X2 K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 484714 PDE12; 2',5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 475134 IREB2; iron-responsive element-binding protein 2 isoform X2 K22416 IREB2; iron-responsive element-binding protein 2
E 490907 HELZ; probable helicase with zinc finger domain isoform X1 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E 485973 HELZ2; helicase with zinc finger domain 2 isoform X5 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 490830 NRDE2; nuclear exosome regulator NRDE2 K26109 NRDE2; nuclear exosome regulator NRDE2
E 490700 SAMD4A; protein Smaug homolog 1 isoform X3 K27396 SMG; protein Smaug
E 484511 SAMD4B; protein Smaug homolog 2 isoform X3 K27396 SMG; protein Smaug
E 481557 FOCAD; focadhesin isoform X1 K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 475395 ribonuclease pancreatic precursor K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
E 611048 RNASE4; ribonuclease 4 precursor K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
E 489416 ZC3H12C; probable ribonuclease ZC3H12C isoform X6 K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 608211 ZC3H12A; endoribonuclease ZC3H12A isoform X1 K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 491921 ZC3H12B; probable ribonuclease ZC3H12B isoform X5 K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 484029 ZC3H12D; probable ribonuclease ZC3H12D isoform X1 K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 119871576 DROSHA; ribonuclease 3 isoform X1 K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 489395 REXO2; oligoribonuclease, mitochondrial K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 479469 ENO3; beta-enolase isoform X2 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 100856683 ENO2; gamma-enolase isoform X2 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 479597 ENO1; alpha-enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 481376 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 478019 PFKP; ATP-dependent 6-phosphofructokinase, platelet type isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 487797 PFKL; ATP-dependent 6-phosphofructokinase, liver type isoform X2 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 403849 PFKM; ATP-dependent 6-phosphofructokinase, muscle type isoform X7 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 474697 HSPA9; stress-70 protein, mitochondrial isoform X1 K04043 dnaK; molecular chaperone DnaK
E 478854 HSPD1; 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 608606 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 477787 EXOSC1; exosome complex component CSL4 isoform X2 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 482086 EXOSC4; exosome complex component RRP41 isoform X2 K11600 RRP41; exosome complex component RRP41
E 476654 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
D Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024