+E Ubiquitin system KO
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Ubiquitin System - Canis lupus familiaris (dog)
%
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C 479513 UBB; polyubiquitin-B K04551 UBB; ubiquitin B
C 403722 UBA52; ubiquitin-60S ribosomal protein L40 K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 102151129 ubiquitin-60S ribosomal protein L40-like K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 474599 RPS27A; ubiquitin-40S ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C 480265 NEDD8; NEDD8 K12158 NEDD8; ubiquitin-like protein Nedd8
C 483748 FAU; ubiquitin-like protein fubi and ribosomal protein S30 K02983 RP-S30e; small subunit ribosomal protein S30e
C 100855547 ubiquitin-like protein FUBI K02983 RP-S30e; small subunit ribosomal protein S30e
C 100855667 ISG15; ubiquitin-like protein ISG15 K12159 ISG15; ubiquitin cross-reactive protein
C 100856530 SUMO3; small ubiquitin-related modifier 3 isoform X3 K12160 SUMO; small ubiquitin-related modifier
C 474963 SUMO2; small ubiquitin-related modifier 2 K12160 SUMO; small ubiquitin-related modifier
C 478874 SUMO1; small ubiquitin-related modifier 1 K12160 SUMO; small ubiquitin-related modifier
C 119871262 small ubiquitin-related modifier 2-like isoform X1 K12160 SUMO; small ubiquitin-related modifier
C 490297 small ubiquitin-related modifier 2-like K12160 SUMO; small ubiquitin-related modifier
C 479646 GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2 isoform X1 K08341 GABARAP; GABA(A) receptor-associated protein
C 479479 GABARAP; gamma-aminobutyric acid receptor-associated protein K08341 GABARAP; GABA(A) receptor-associated protein
C 612919 GABARAPL1; gamma-aminobutyric acid receptor-associated protein-like 1 K08341 GABARAP; GABA(A) receptor-associated protein
C 474636 ATG12; ubiquitin-like protein ATG12 isoform X2 K08336 ATG12; ubiquitin-like protein ATG12
C 608549 URM1; ubiquitin-related modifier 1 K12161 URM1; ubiquitin related modifier 1
C 477297 UFM1; ubiquitin-fold modifier 1 isoform X2 K12162 UFM1; ubiquitin-fold modifier 1
C 477752 ZFAND4; AN1-type zinc finger protein 4 K12163 ZFAND4; AN1-type zinc finger protein 4
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C 480896 UBA1; ubiquitin-like modifier-activating enzyme 1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C 476425 SAE1; SUMO-activating enzyme subunit 1 isoform X4 K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C 476490 UBA2; SUMO-activating enzyme subunit 2 isoform X3 K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C 476560 UBA3; NEDD8-activating enzyme E1 catalytic subunit isoform X3 K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C 610026 NAE1; NEDD8-activating enzyme E1 regulatory subunit isoform X1 K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C 485928 MOCS3; adenylyltransferase and sulfurtransferase MOCS3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C 100856526 UBA5; ubiquitin-like modifier-activating enzyme 5 isoform X1 K12164 UBA5; ubiquitin-like modifier-activating enzyme 5
C 608118 UBA7; ubiquitin-like modifier-activating enzyme 7 isoform X1 K10698 UBE1L; ubiquitin-activating enzyme E1-like [EC:6.2.1.45]
C 475160 UBA6; ubiquitin-like modifier-activating enzyme 6 isoform X2 K10699 UBE1L2; ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]
C 476533 ATG7; ubiquitin-like modifier-activating enzyme ATG7 isoform X2 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C 492095 UBE2A; ubiquitin-conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C 119870395 ubiquitin-conjugating enzyme E2 A-like K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C 474683 UBE2B; ubiquitin-conjugating enzyme E2 B K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
C 100856010 ubiquitin-conjugating enzyme E2 B-like isoform X2 K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
C 485898 UBE2C; ubiquitin-conjugating enzyme E2 C isoform X1 K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C 481325 ubiquitin-conjugating enzyme E2 C-like K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C 478495 UBE2D3; ubiquitin-conjugating enzyme E2 D3 isoform X2 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 608578 UBE2D1; ubiquitin-conjugating enzyme E2 D1 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 612742 UBE2D2; ubiquitin-conjugating enzyme E2 D2 isoform X1 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 475563 ubiquitin-conjugating enzyme E2 E1-like K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 477048 UBE2E1; ubiquitin-conjugating enzyme E2 E1 isoform X1 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 610187 UBE2E2; ubiquitin-conjugating enzyme E2 E2 isoform X1 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 612823 UBE2E3; ubiquitin-conjugating enzyme E2 E3 isoform X1 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 100685242 UBE2G1; ubiquitin-conjugating enzyme E2 G1 isoform X1 K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C 611581 UBE2G2; ubiquitin-conjugating enzyme E2 G2 isoform X3 K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C 607816 UBE2H; ubiquitin-conjugating enzyme E2 H isoform X3 K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C 474993 UBE2J1; ubiquitin-conjugating enzyme E2 J1 K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
C 606935 UBE2J2; ubiquitin-conjugating enzyme E2 J2 K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C 609531 UBE2K; ubiquitin-conjugating enzyme E2 K isoform X1 K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C 477572 UBE2L3; ubiquitin-conjugating enzyme E2 L3 isoform X2 K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 102155658 ubiquitin-conjugating enzyme E2 L3-like K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 475967 UBE2L6; ubiquitin/ISG15-conjugating enzyme E2 L6 isoform X2 K04553 UBE2L6; ubiquitin/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]
C 607817 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 611865 UBE2N; ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 610206 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 608680 ubiquitin-conjugating enzyme E2 N-like isoform X2 K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 607889 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 609637 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 100684029 ubiquitin-conjugating enzyme E2 N-like isoform X4 K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 476784 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 611801 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 609108 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 479932 ubiquitin-conjugating enzyme E2 N-like isoform X2 K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 106558148 LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 111094434 LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 119863875 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 483330 UBE2O; (E3-independent) E2 ubiquitin-conjugating enzyme isoform X2 K10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
C 478374 UBE2Q2; ubiquitin-conjugating enzyme E2 Q2 isoform X2 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 488058 UBE2QL1; ubiquitin-conjugating enzyme E2Q-like protein 1 isoform X1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 100688676 UBE2Q1; ubiquitin-conjugating enzyme E2 Q1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 611799 UBE2R2; ubiquitin-conjugating enzyme E2 R2 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 476759 CDC34; ubiquitin-conjugating enzyme E2 R1 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 102155320 LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 R2-like K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 403671 UBE2S; ubiquitin-conjugating enzyme E2 S K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
C 607154 UBE2T; ubiquitin-conjugating enzyme E2 T K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
C 609932 UBE2U; ubiquitin-conjugating enzyme E2 U isoform X1 K10584 UBE2U; ubiquitin-conjugating enzyme E2 U [EC:2.3.2.23]
C 486999 UBE2W; ubiquitin-conjugating enzyme E2 W isoform X1 K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C 491062 UBE2Z; ubiquitin-conjugating enzyme E2 Z K10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]
C 475718 BIRC6; baculoviral IAP repeat-containing protein 6 isoform X47 K10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
B UBL-conjugating enzymes
C 491332 UBE2I; SUMO-conjugating enzyme UBC9 K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C 477421 UBE2F; NEDD8-conjugating enzyme UBE2F isoform X1 K10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]
C 484221 UBE2M; NEDD8-conjugating enzyme Ubc12 K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C 475967 UBE2L6; ubiquitin/ISG15-conjugating enzyme E2 L6 isoform X2 K04553 UBE2L6; ubiquitin/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]
C 478564 ATG3; ubiquitin-like-conjugating enzyme ATG3 isoform X1 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
C 610103 ATG10; ubiquitin-like-conjugating enzyme ATG10 isoform X1 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
C 478978 UFC1; ubiquitin-fold modifier-conjugating enzyme 1 K12165 UFC1; ufm1-conjugating enzyme 1
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AUbiquitin ligases (E3)
B HECT type E3
C 479010 UBE3A; ubiquitin-protein ligase E3A isoform X3 K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
C 486311 UBE3B; ubiquitin-protein ligase E3B isoform X1 K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]
C 482822 UBE3C; ubiquitin-protein ligase E3C isoform X4 K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C 481900 UBE3D; E3 ubiquitin-protein ligase E3D isoform X2 K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]
C 608821 SMURF1; E3 ubiquitin-protein ligase SMURF1 isoform X1 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 480470 SMURF2; E3 ubiquitin-protein ligase SMURF2 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 477199 ITCH; E3 ubiquitin-protein ligase Itchy homolog isoform X2 K05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
C 100856769 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X4 K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
C 479672 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 K05630 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26]
C 477400 TRIP12; E3 ubiquitin-protein ligase TRIP12 isoform X1 K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C 608738 NEDD4; E3 ubiquitin-protein ligase NEDD4 isoform X1 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C 476189 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like isoform X16 K13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]
C 480931 HUWE1; E3 ubiquitin-protein ligase HUWE1 isoform X7 K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C 490785 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 isoform X1 K22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]
C 475055 UBR5; E3 ubiquitin-protein ligase UBR5 isoform X5 K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]
C 490639 G2E3; G2/M phase-specific E3 ubiquitin-protein ligase isoform X2 K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]
C 487592 HERC1; probable E3 ubiquitin-protein ligase HERC1 isoform X1 K10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]
C 479005 HERC2; E3 ubiquitin-protein ligase HERC2 isoform X2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
C 478475 HERC3; probable E3 ubiquitin-protein ligase HERC3 isoform X1 K10614 HERC3; E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]
C 479225 HERC4; probable E3 ubiquitin-protein ligase HERC4 isoform X5 K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]
C 475010 HACE1; E3 ubiquitin-protein ligase HACE1 isoform X4 K12166 HACE1; E3 ubiquitin-protein ligase HACE1 [EC:2.3.2.26]
C 475868 HECW1; E3 ubiquitin-protein ligase HECW1 isoform X9 K12167 HECW1; E3 ubiquitin-protein ligase HECW1 [EC:2.3.2.26]
C 100685500 HECW2; E3 ubiquitin-protein ligase HECW2 isoform X5 K12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]
C 480284 HECTD1; E3 ubiquitin-protein ligase HECTD1 isoform X2 K12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]
C 486795 HECTD2; probable E3 ubiquitin-protein ligase HECTD2 isoform X1 K12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]
C 482518 HECTD3; E3 ubiquitin-protein ligase HECTD3 isoform X1 K12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]
C 477486 HECTD4; probable E3 ubiquitin-protein ligase HECTD4 isoform X6 K17849 HECTD4; E3 ubiquitin-protein ligase HECTD4 [EC:2.3.2.26]
C HECT type E3 associated proteins
D 478044 NDFIP1; NEDD4 family-interacting protein 1 K25839 NDFIP; NEDD4 family-interacting protein
D 476956 NDFIP2; NEDD4 family-interacting protein 2 K25839 NDFIP; NEDD4 family-interacting protein
D 481446 N4BP3; NEDD4-binding protein 3 K26473 N4BP3; NEDD4-binding protein 3
B U-box type E3
C 479418 UBE4A; ubiquitin conjugation factor E4 A K10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]
C 479603 UBE4B; ubiquitin conjugation factor E4 B isoform X1 K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C 479892 STUB1; E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 477573 PPIL2; RING-type E3 ubiquitin-protein ligase PPIL2 isoform X1 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C 611552 PRPF19; pre-mRNA-processing factor 19 isoform X1 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
C 479802 RBBP6; E3 ubiquitin-protein ligase RBBP6 isoform X2 K10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]
C 100684685 UBOX5; RING finger protein 37 isoform X1 K10600 UBOX5; U-box domain-containing protein 5
B Single Ring-finger type E3
C BRE1 proteins
D 474788 RNF20; E3 ubiquitin-protein ligase BRE1A isoform X2 K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
D 489913 RNF40; E3 ubiquitin-protein ligase BRE1B K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
D 489369 CBL; E3 ubiquitin-protein ligase CBL isoform X2 K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
D 487965 CBLB; E3 ubiquitin-protein ligase CBL-B isoform X1 K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
D 612343 CBLC; E3 ubiquitin-protein ligase CBL-C isoform X1 K22518 CBLC; E3 ubiquitin-protein ligase CBL-C [EC:2.3.2.27]
C SINA (Seven in absentia) proteins
D 100856496 SIAH1; E3 ubiquitin-protein ligase SIAH1 isoform X1 K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 100683719 SIAH2; E3 ubiquitin-protein ligase SIAH2 K08742 SIAH2; E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27]
C Ligand of Numb proteins
D 475143 LNX1; E3 ubiquitin-protein ligase LNX isoform X1 K10692 LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
D 486031 LNX2; ligand of Numb protein X 2 isoform X1 K10692 LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
D 100687532 PDZRN3; E3 ubiquitin-protein ligase PDZRN3 isoform X4 K15682 PDZRN3_4; ligand of Numb protein X 3/4 [EC:2.3.2.27]
C March proteins
D 612618 MARCHF1; E3 ubiquitin-protein ligase MARCHF1 isoform X5 K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 606989 MARCHF8; E3 ubiquitin-protein ligase MARCHF8 isoform X1 K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 611624 MARCHF2; E3 ubiquitin-protein ligase MARCHF2 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 481488 MARCHF3; E3 ubiquitin-protein ligase MARCHF3 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 488515 MARCHF4; E3 ubiquitin-protein ligase MARCHF4 K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 481132 MARCHF9; E3 ubiquitin-protein ligase MARCHF9 K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 479384 MARCHF11; E3 ubiquitin-protein ligase MARCHF11 isoform X5 K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 612766 MARCHF5; E3 ubiquitin-protein ligase MARCHF5 isoform X2 K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D 478617 MARCHF6; E3 ubiquitin-protein ligase MARCHF6 isoform X2 K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
D 478763 MARCHF7; E3 ubiquitin-protein ligase MARCHF7 isoform X2 K10662 MARCH7; E3 ubiquitin-protein ligase MARCH7 [EC:2.3.2.27]
D 490914 MARCHF10; probable E3 ubiquitin-protein ligase MARCHF10 isoform X4 K10665 MARCH10; E3 ubiquitin-protein ligase MARCH10 [EC:2.3.2.27]
C MDM2/MDM4 proteins
D 403693 MDM2; E3 ubiquitin-protein ligase Mdm2 K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
D 478939 MDM4; protein Mdm4 isoform X1 K10127 MDM4; protein Mdm4
C NFX1 proteins
D 481581 NFX1; transcriptional repressor NF-X1 isoform X1 K12236 NFX1; transcriptional repressor NF-X1
D 100687977 NFXL1; NF-X1-type zinc finger protein NFXL1 K15683 NFXL1; NF-X1-type zinc finger protein NFXL1
C Pellino proteins
D 481388 PELI1; E3 ubiquitin-protein ligase pellino homolog 1 K11964 PELI; pellino [EC:2.3.2.27]
D 483710 PELI3; E3 ubiquitin-protein ligase pellino homolog 3 isoform X3 K11964 PELI; pellino [EC:2.3.2.27]
D 106559103 PELI2; E3 ubiquitin-protein ligase pellino homolog 2 isoform X1 K11964 PELI; pellino [EC:2.3.2.27]
C Peripheral membrane proteins
D 100856251 PEX10; peroxisome biogenesis factor 10 K13346 PEX10; peroxin-10
D 491139 PEX12; peroxisome assembly protein 12 K13345 PEX12; peroxin-12
D 487007 PEX2; peroxisome biogenesis factor 2 K06664 PEX2; peroxin-2
C RBR proteins
D 612316 PRKN; E3 ubiquitin-protein ligase parkin isoform X1 K04556 PARK2; parkin [EC:2.3.2.31]
D 475226 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 isoform X1 K11967 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 [EC:2.3.2.31]
D 478359 ARIH1; E3 ubiquitin-protein ligase ARIH1 isoform X2 K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D 476633 ARIH2; E3 ubiquitin-protein ligase ARIH2 isoform X1 K11969 ARIH2; ariadne-2 [EC:2.3.2.31]
D 485818 RBCK1; ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X2 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 478042 RNF14; E3 ubiquitin-protein ligase RNF14 isoform X1 K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
D 475049 RNF19A; E3 ubiquitin-protein ligase RNF19A K11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]
D 478146 RNF19B; E3 ubiquitin-protein ligase RNF19B isoform X2 K11973 RNF19B; E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.31]
D 480259 RNF31; E3 ubiquitin-protein ligase RNF31 isoform X1 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
D 477470 RNF34; E3 ubiquitin-protein ligase RNF34 isoform X8 K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
D 491144 RFFL; E3 ubiquitin-protein ligase rififylin isoform X13 K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
D 488237 RNF144B; E3 ubiquitin-protein ligase RNF144B K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
D 609037 RNF144A; E3 ubiquitin-protein ligase RNF144A isoform X1 K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
D 488029 RNF168; E3 ubiquitin-protein ligase RNF168 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
D 609300 RNF169; E3 ubiquitin-protein ligase RNF169 K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
D 100684892 RNF183; E3 ubiquitin-protein ligase RNF183 isoform X6 K22157 RNF183; E3 ubiquitin-protein ligase RNF183 [EC:2.3.2.31]
D 479760 RNF216; E3 ubiquitin-protein ligase RNF216 isoform X9 K11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]
D 484112 RNF217; probable E3 ubiquitin-protein ligase RNF217 isoform X1 K11977 RNF217; E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.31]
C TRAF proteins
D 480673 TRAF2; TNF receptor-associated factor 2 isoform X2 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
D 480019 TRAF5; TNF receptor-associated factor 5 K09849 TRAF5; TNF receptor-associated factor 5
D 100688110 TRAF6; TNF receptor-associated factor 6 K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
D 609824 TRAF7; E3 ubiquitin-protein ligase TRAF7 isoform X3 K10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]
C TRIM/RBCC proteins
D 481012 MID2; probable E3 ubiquitin-protein ligase MID2 isoform X3 K10647 TRIM1; midline 2 [EC:2.3.2.27]
D 476834 TRIM3; tripartite motif-containing protein 3 K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 106559757 TRIM2; tripartite motif-containing protein 2 isoform X1 K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 608654 TRIM4; E3 ubiquitin-protein ligase TRIM4 isoform X1 K11998 TRIM4; tripartite motif-containing protein 4 [EC:2.3.2.27]
D 485284 TRIM22; E3 ubiquitin-protein ligase TRIM22 isoform X1 K11999 TRIM6_22_34; tripartite motif-containing protein 6/22/34
D 100568301 TRIM6; tripartite motif-containing protein 6 K11999 TRIM6_22_34; tripartite motif-containing protein 6/22/34
D 100568302 TRIM34; tripartite motif-containing protein 34 K11999 TRIM6_22_34; tripartite motif-containing protein 6/22/34
D 491670 TRIM7; E3 ubiquitin-protein ligase TRIM7 isoform X2 K12000 TRIM7; tripartite motif-containing protein 7
D 486863 TRIM8; E3 ubiquitin-protein ligase TRIM8 K12001 TRIM8; tripartite motif-containing protein 8 [EC:2.3.2.27]
D 490687 TRIM9; E3 ubiquitin-protein ligase TRIM9 isoform X9 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 608010 TRIM67; tripartite motif-containing protein 67 isoform X1 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 482205 TRIM11; E3 ubiquitin-protein ligase TRIM11 K10650 TRIM11; tripartite motif-containing protein 11 [EC:2.3.2.27]
D 607845 TRIM13; E3 ubiquitin-protein ligase TRIM13 K12003 TRIM13; tripartite motif-containing protein 13 [EC:2.3.2.27]
D 612123 TRIM14; tripartite motif-containing protein 14 isoform X1 K12004 TRIM14; tripartite motif-containing protein 14
D 489518 TRIM16; tripartite motif-containing protein 16 K12006 TRIM16; tripartite motif-containing protein 16
D 482204 TRIM17; E3 ubiquitin-protein ligase TRIM17 isoform X4 K12007 TRIM17; tripartite motif-containing protein 17 [EC:2.3.2.27]
D 491737 MID1; E3 ubiquitin-protein ligase Midline-1 isoform X2 K08285 TRIM18; midline 1 [EC:2.3.2.27]
D 485226 TRIM21; E3 ubiquitin-protein ligase TRIM21 K10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]
D 487232 TRIM23; E3 ubiquitin-protein ligase TRIM23 isoform X3 K07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]
D 609728 TRIM24; transcription intermediary factor 1-alpha isoform X6 K08881 TRIM24; tripartite motif-containing protein 24 [EC:2.3.2.27]
D 491103 TRIM25; E3 ubiquitin/ISG15 ligase TRIM25 K10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]
D 100685827 TRIM27; zinc finger protein RFP K12009 TRIM27; tripartite motif-containing protein 27 [EC:2.3.2.27]
D 403689 TRIM28; transcription intermediary factor 1-beta isoform X1 K08882 TRIM28; tripartite motif-containing protein 28 [EC:2.3.2.27]
D 489362 TRIM29; tripartite motif-containing protein 29 isoform X8 K12010 TRIM29; tripartite motif-containing protein 29
D 102152434 TRIM32; E3 ubiquitin-protein ligase TRIM32 K10607 TRIM32; tripartite motif-containing protein 32 [EC:2.3.2.27]
D 475804 TRIM33; E3 ubiquitin-protein ligase TRIM33 isoform X1 K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
D 486103 TRIM35; tripartite motif-containing protein 35 K12012 TRIM35; tripartite motif-containing protein 35
D 474639 TRIM36; E3 ubiquitin-protein ligase TRIM36 isoform X1 K12013 TRIM36; tripartite motif-containing protein 36 [EC:2.3.2.27]
D 480575 TRIM37; E3 ubiquitin-protein ligase TRIM37 isoform X8 K10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]
D 488257 TRIM38; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIM38 isoform X1 K12014 TRIM38; tripartite motif-containing protein 38 [EC:2.3.2.27]
D 491669 TRIM41; E3 ubiquitin-protein ligase TRIM41 isoform X3 K12017 TRIM41; tripartite motif-containing protein 41 [EC:2.3.2.27]
D 477094 TRIM42; tripartite motif-containing protein 42 isoform X6 K12018 TRIM42; tripartite motif-containing protein 42
D 485141 tripartite motif-containing protein 77-like K12019 TRIM43S; tripartite motif-containing protein 43/48/49/64/77
D 485143 tripartite motif-containing protein 64 K12019 TRIM43S; tripartite motif-containing protein 43/48/49/64/77
D 608075 tripartite motif-containing protein 43-like isoform X2 K12019 TRIM43S; tripartite motif-containing protein 43/48/49/64/77
D 483424 TRIM44; tripartite motif-containing protein 44 isoform X2 K12020 TRIM44; tripartite motif-containing protein 44
D 475811 TRIM45; tripartite motif-containing protein 45 isoform X3 K12021 TRIM45; tripartite motif-containing protein 45
D 490429 TRIM46; tripartite motif-containing protein 46 isoform X1 K12022 TRIM46; tripartite motif-containing protein 46
D 609519 TRIM47; E3 ubiquitin-protein ligase TRIM47 isoform X5 K12023 TRIM47; tripartite motif-containing protein 47
D 483307 TRIM80; E3 ubiquitin-protein ligase TRIM47-like isoform X1 K12023 TRIM47; tripartite motif-containing protein 47
D 489811 TRIM50; E3 ubiquitin-protein ligase TRIM50 isoform X6 K12024 TRIM50_73_74; tripartite motif-containing protein 50/73/74
D 100683996 TRIM52; E3 ubiquitin-protein ligase TRIM52 isoform X1 K12025 TRIM52; tripartite motif-containing protein 52
D 475701 TRIM54; tripartite motif-containing protein 54 isoform X1 K10653 TRIM54; tripartite motif-containing protein 54
D 486976 TRIM55; tripartite motif-containing protein 55 isoform X6 K10654 TRIM55; tripartite motif-containing protein 55
D 608281 TRIM56; E3 ubiquitin-protein ligase TRIM56 K12026 TRIM56; tripartite motif-containing protein 56 [EC:2.3.2.27]
D 482216 TRIM58; E3 ubiquitin-protein ligase TRIM58 K12027 TRIM58; tripartite motif-containing protein 58 [EC:2.3.2.27]
D 488133 TRIM59; tripartite motif-containing protein 59 K12028 TRIM59; tripartite motif-containing protein 59
D 100686962 TRIM61; LOW QUALITY PROTEIN: putative tripartite motif-containing protein 61 K12029 TRIM60_61; tripartite motif-containing protein 60/61
D 100686793 TRIM60; LOW QUALITY PROTEIN: tripartite motif-containing protein 60 K12029 TRIM60_61; tripartite motif-containing protein 60/61
D 487300 TRIM62; E3 ubiquitin-protein ligase TRIM62 K12030 TRIM62; tripartite motif-containing protein 62 [EC:2.3.2.27]
D 487362 TRIM63; E3 ubiquitin-protein ligase TRIM63 isoform X2 K10655 TRIM63; tripartite motif-containing protein 63 [EC:2.3.2.27]
D 609505 TRIM65; tripartite motif-containing protein 65 isoform X2 K12031 TRIM65; tripartite motif-containing protein 65
D 485379 TRIM66; tripartite motif-containing protein 66 isoform X1 K12032 TRIM66; tripartite motif-containing protein 66
D 485233 TRIM68; E3 ubiquitin-protein ligase TRIM68 isoform X1 K12033 TRIM68; tripartite motif-containing protein 68 [EC:2.3.2.27]
D 478285 TRIM69; E3 ubiquitin-protein ligase TRIM69 isoform X2 K12034 TRIM69; tripartite motif-containing protein 69 [EC:2.3.2.27]
D 477014 TRIM71; E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 489927 TRIM72; tripartite motif-containing protein 72 K12036 TRIM72; tripartite motif-containing protein 72
C UBR box proteins
D 487521 UBR1; E3 ubiquitin-protein ligase UBR1 isoform X1 K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D 474903 UBR2; E3 ubiquitin-protein ligase UBR2 isoform X1 K10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]
D 478789 UBR3; E3 ubiquitin-protein ligase UBR3 isoform X1 K11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]
D 478211 UBR4; E3 ubiquitin-protein ligase UBR4 isoform X6 K10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
D 480419 UBR7; putative E3 ubiquitin-protein ligase UBR7 K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D 487269 AMFR; E3 ubiquitin-protein ligase AMFR isoform X3 K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 487796 AIRE; autoimmune regulator K10603 AIRE; autoimmune regulator
D 489998 BFAR; bifunctional apoptosis regulator K15684 BFAR; bifunctional apoptosis regulator
D 479464 BIRC2; baculoviral IAP repeat-containing protein 2 K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 489433 BIRC3; baculoviral IAP repeat-containing protein 3 K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 442989 XIAP; E3 ubiquitin-protein ligase XIAP K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
D 485969 BIRC7; baculoviral IAP repeat-containing protein 7 K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
D 486271 BRAP; LOW QUALITY PROTEIN: BRCA1-associated protein isoform X1 K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D 403437 BRCA1; breast cancer type 1 susceptibility protein homolog K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
D 483262 CBLL1; E3 ubiquitin-protein ligase Hakai isoform X2 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D 482554 CCNB1IP1; E3 ubiquitin-protein ligase CCNB1IP1 isoform X1 K10639 CCNB1IP1; E3 ubiquitin-protein ligase CCNP1IP1 [EC:2.3.2.27]
D 477434 CHFR; E3 ubiquitin-protein ligase CHFR isoform X1 K10644 CHFR; E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27]
D 482708 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D 490435 DCST1; E3 ubiquitin-protein ligase DCST1 isoform X2 K22375 DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]
D 479723 DTX2; probable E3 ubiquitin-protein ligase DTX2 isoform X1 K06058 DTX; deltex [EC:2.3.2.27]
D 483461 DTX4; E3 ubiquitin-protein ligase DTX4 K06058 DTX; deltex [EC:2.3.2.27]
D 478586 DTX3L; E3 ubiquitin-protein ligase DTX3L isoform X2 K06058 DTX; deltex [EC:2.3.2.27]
D 100687947 DTX3; probable E3 ubiquitin-protein ligase DTX3 isoform X1 K06058 DTX; deltex [EC:2.3.2.27]
D 486276 DTX1; E3 ubiquitin-protein ligase DTX1 isoform X1 K06058 DTX; deltex [EC:2.3.2.27]
D 478555 DZIP3; E3 ubiquitin-protein ligase DZIP3 isoform X4 K10642 DZIP3; E3 ubiquitin-protein ligase DZIP3 [EC:2.3.2.27]
D 612161 FANCL; E3 ubiquitin-protein ligase FANCL isoform X5 K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D 475773 KCMF1; E3 ubiquitin-protein ligase KCMF1 K22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
D 491329 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 isoform X3 K10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]
D 100685637 LTN1; E3 ubiquitin-protein ligase listerin K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D 478061 MAP3K1; mitogen-activated protein kinase kinase kinase 1 K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
D 476195 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C isoform X4 K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 490417 MEX3A; RNA-binding protein MEX3A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 612270 MEX3D; RNA-binding protein MEX3D isoform X1 K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 100855735 MEX3B; RNA-binding protein MEX3B isoform X2 K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 479863 MGRN1; E3 ubiquitin-protein ligase MGRN1 isoform X8 K10604 MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]
D 490521 MIB1; E3 ubiquitin-protein ligase MIB1 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 479566 MIB2; E3 ubiquitin-protein ligase MIB2 isoform X2 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 475528 MKRN1; E3 ubiquitin-protein ligase makorin-1 isoform X2 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 476531 MKRN2; probable E3 ubiquitin-protein ligase makorin-2 isoform X1 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 102152441 MKRN3; LOW QUALITY PROTEIN: probable E3 ubiquitin-protein ligase makorin-3 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 487394 MUL1; mitochondrial ubiquitin ligase activator of NFKB 1 isoform X2 K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
D 476952 MYCBP2; E3 ubiquitin-protein ligase MYCBP2 isoform X13 K10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]
D 488230 MYLIP; E3 ubiquitin-protein ligase MYLIP K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D 489118 NEURL1B; E3 ubiquitin-protein ligase NEURL1B isoform X1 K01931 NEUR; protein neuralized [EC:2.3.2.27]
D 486873 NEURL1; E3 ubiquitin-protein ligase NEURL1 isoform X4 K01931 NEUR; protein neuralized [EC:2.3.2.27]
D 102152163 NEURL3; E3 ubiquitin-protein ligase NEURL3 K15689 NEURL3; E3 ubiquitin-protein ligase NEURL3 [EC:2.3.2.27]
D 474161 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 K10602 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 [EC:2.3.2.27]
D 476954 OBI1; ORC ubiquitin ligase 1 K24091 OBI1; ORC ubiquitin ligase 1 [EC:2.3.2.27]
D 480949 PJA1; E3 ubiquitin-protein ligase Praja-1 isoform X1 K10633 PJA1; E3 ubiquitin-protein ligase Praja1 [EC:2.3.2.27]
D 479143 PJA2; E3 ubiquitin-protein ligase Praja-2 K10634 PJA2; E3 ubiquitin-protein ligase Praja2 [EC:2.3.2.27]
D 476544 RAD18; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RAD18 isoform X1 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 483420 RAG1; V(D)J recombination-activating protein 1 K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
D 612746 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 isoform X7 K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
D 480065 RC3H1; roquin-1 isoform X1 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 491344 RC3H2; roquin-2 isoform X1 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 480060 COP1; E3 ubiquitin-protein ligase COP1 isoform X6 K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
D 610424 RFWD3; E3 ubiquitin-protein ligase RFWD3 isoform X2 K15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]
D 480042 RNF2; E3 ubiquitin-protein ligase RING2 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 607905 RING1; E3 ubiquitin-protein ligase RING1 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 100855762 RNF4; E3 ubiquitin-protein ligase RNF4 K22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]
D 474858 RNF5; E3 ubiquitin-protein ligase RNF5 isoform X8 K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 486362 RNF185; E3 ubiquitin-protein ligase RNF185 isoform X3 K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 477332 RNF6; E3 ubiquitin-protein ligase RNF6 isoform X1 K22753 RNF6; E3 ubiquitin-protein ligase RNF6 [EC:2.3.2.27]
D 481775 RNF8; E3 ubiquitin-protein ligase RNF8 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
D 477514 RNF10; RING finger protein 10 isoform X2 K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D 475358 RNF11; RING finger protein 11 isoform X2 K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D 491965 RLIM; E3 ubiquitin-protein ligase RLIM K16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]
D 491808 E3 ubiquitin-protein ligase RLIM-like K16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]
D 477109 RNF13; E3 ubiquitin-protein ligase RNF13 isoform X1 K15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]
D 478912 RNF25; E3 ubiquitin-protein ligase RNF25 K10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]
D 489367 RNF26; E3 ubiquitin-protein ligase RNF26 K15693 RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]
D 474766 RNF38; E3 ubiquitin-protein ligase RNF38 isoform X1 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 489101 RNF44; RING finger protein 44 isoform X2 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 607044 RNF41; E3 ubiquitin-protein ligase NRDP1 K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 491114 RNF43; E3 ubiquitin-protein ligase RNF43 isoform X1 K15694 RNF43; E3 ubiquitin-protein ligase RNF43 [EC:2.3.2.27]
D 475761 RNF103; E3 ubiquitin-protein ligase RNF103 K15695 RNF103; E3 ubiquitin-protein ligase RNF103 [EC:2.3.2.27]
D 478323 RNF111; E3 ubiquitin-protein ligase Arkadia isoform X4 K10635 RNF111; E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27]
D 100855441 RNF112; RING finger protein 112 isoform X2 K25173 RNF112; E3 ubiquitin-protein ligase RNF112 [EC:2.3.2.27]
D 477261 RNF114; E3 ubiquitin-protein ligase RNF114 K15697 RNF114; E3 ubiquitin-protein ligase RNF114 [EC:2.3.2.27]
D 485101 RNF126; E3 ubiquitin-protein ligase RNF126 isoform X1 K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 612818 RNF115; E3 ubiquitin-protein ligase RNF115 isoform X2 K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 476819 RNF121; RING finger protein 121 isoform X2 K15698 RNF121_175; RING finger protein 121/175
D 612478 RNF175; RING finger protein 175 isoform X4 K15698 RNF121_175; RING finger protein 121/175
D 608382 RNF122; RING finger protein 122 isoform X1 K15699 RNF122; RING finger protein 122
D 484767 RNF123; E3 ubiquitin-protein ligase RNF123 isoform X5 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 490498 RNF125; E3 ubiquitin-protein ligase RNF125 isoform X2 K12170 RNF125; E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27]
D 492051 RNF128; E3 ubiquitin-protein ligase RNF128 isoform X3 K10629 RNF128; E3 ubiquitin-protein ligase RNF128 [EC:2.3.2.27]
D 474651 RNF130; E3 ubiquitin-protein ligase RNF130 isoform X1 K15701 RNF130; E3 ubiquitin-protein ligase RNF130 [EC:2.3.2.27]
D 102152555 RNF133; E3 ubiquitin-protein ligase RNF133 K15702 RNF133; E3 ubiquitin-protein ligase RNF133 [EC:2.3.2.27]
D 480614 RNF135; E3 ubiquitin-protein ligase RNF135 isoform X1 K16272 RNF135; E3 ubiquitin-protein ligase RNF135 [EC:2.3.2.27]
D 480165 RNF138; E3 ubiquitin-protein ligase RNF138 isoform X3 K10668 RNF138; E3 ubiquitin-protein ligase RNF138 [EC:2.3.2.27]
D 609422 RNF139; E3 ubiquitin-protein ligase RNF139 K15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]
D 489154 RNF145; RING finger protein 145 K23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]
D 476288 RNF146; E3 ubiquitin-protein ligase RNF146 isoform X1 K15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]
D 481333 RNF149; E3 ubiquitin-protein ligase RNF149 K15704 RNF149; E3 ubiquitin-protein ligase RNF149 [EC:2.3.2.27]
D 609935 RNF152; E3 ubiquitin-protein ligase RNF152 K15705 RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]
D 483327 RNF157; E3 ubiquitin ligase RNF157 isoform X1 K25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]
D 490468 RNF165; E3 ubiquitin-protein ligase RNF165 isoform X2 K17821 RNF165; E3 ubiquitin-protein ligase RNF165 [EC:2.3.2.27]
D 608926 RNF166; E3 ubiquitin-protein ligase RNF166 K17044 RNF166; E3 ubiquitin-protein ligase RNF166 [EC:2.3.2.27]
D 489456 RNF167; E3 ubiquitin-protein ligase RNF167 isoform X1 K15706 RNF167; E3 ubiquitin-protein ligase RNF167 [EC:2.3.2.27]
D 475568 RNF170; E3 ubiquitin-protein ligase RNF170 isoform X2 K15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]
D 487231 RNF180; E3 ubiquitin-protein ligase RNF180 isoform X1 K15708 RNF180; E3 ubiquitin-protein ligase RNF180 [EC:2.3.2.27]
D 475768 RNF181; E3 ubiquitin-protein ligase RNF181 K22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
D 488225 RNF182; E3 ubiquitin-protein ligase RNF182 K11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]
D 487400 RNF186; E3 ubiquitin-protein ligase RNF186 K25214 RNF186; E3 ubiquitin-protein ligase RNF186 [EC:2.3.2.27]
D 119866945 RNF187; E3 ubiquitin-protein ligase RNF187 K15709 RNF187; E3 ubiquitin-protein ligase RNF187 [EC:2.3.2.27]
D 483355 RNF213; E3 ubiquitin-protein ligase RNF213 isoform X1 K22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]
D 612846 RNF220; E3 ubiquitin-protein ligase RNF220 isoform X10 K25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]
D 480581 RNFT1; E3 ubiquitin-protein ligase RNFT1 K22379 RNFT1; E3 ubiquitin-protein ligase RNFT1 [EC:2.3.2.27]
D 483721 SART1; U4/U6.U5 tri-snRNP-associated protein 1 isoform X1 K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D 476233 SHPRH; E3 ubiquitin-protein ligase SHPRH K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D 612744 SH3RF1; E3 ubiquitin-protein ligase SH3RF1 isoform X3 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 478049 SH3RF2; E3 ubiquitin-protein ligase SH3RF2 isoform X1 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 481304 SH3RF3; E3 ubiquitin-protein ligase SH3RF3 isoform X1 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 477106 HLTF; helicase-like transcription factor isoform X4 K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 483746 SYVN1; E3 ubiquitin-protein ligase synoviolin isoform X2 K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D 608955 TMEM129; E3 ubiquitin-protein ligase TM129 isoform X1 K22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]
D 481577 TOPORS; E3 ubiquitin-protein ligase Topors isoform X1 K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
D 608724 TRAIP; E3 ubiquitin-protein ligase TRAIP isoform X2 K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D 478414 TTC3; E3 ubiquitin-protein ligase TTC3 isoform X1 K15712 TTC3; E3 ubiquitin-protein ligase TTC3 [EC:2.3.2.27]
D 611463 UHRF1; E3 ubiquitin-protein ligase UHRF1 isoform X1 K10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
D 474702 UHRF2; E3 ubiquitin-protein ligase UHRF2 isoform X2 K15713 UHRF2; E3 ubiquitin-protein ligase UHRF2 [EC:2.3.2.27]
D 490077 UNKL; putative E3 ubiquitin-protein ligase UNKL isoform X6 K23047 UNKL; E3 ubiquitin-protein ligase UNKL [EC:2.3.2.27]
D 490061 ZNF598; E3 ubiquitin-protein ligase ZNF598 isoform X5 K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D 475962 ZFP91; E3 ubiquitin-protein ligase ZFP91 isoform X2 K25175 ZFP91; E3 ubiquitin-protein ligase ZFP91 [EC:2.3.2.27]
D 611591 ZNRF2; E3 ubiquitin-protein ligase ZNRF2 K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
D 100687514 ZNRF1; E3 ubiquitin-protein ligase ZNRF1 K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
D 486339 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 isoform X2 K16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]
D 485029 ZNRF4; E3 ubiquitin-protein ligase ZNRF4 isoform X4 K15715 ZNRF4; E3 ubiquitin-protein ligase ZNRF4 [EC:2.3.2.27]
D 478832 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2 K15716 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2 [EC:2.3.2.27]
B Atypical E3
C 481508 JADE2; E3 ubiquitin-protein ligase Jade-2 isoform X1 K22155 JADE2; E3 ubiquitin-protein ligase Jade-2 [EC:2.3.2.27]
C 100683433 E4F1; transcription factor E4F1 isoform X1 K22401 E4F1; transcription factor E4F1 / E3 ubiquitin-protein ligase [EC:2.3.2.27]
C 479800 NSMCE1; non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
C 100685860 IRF2BPL; probable E3 ubiquitin-protein ligase IRF2BPL K22383 IRF2BP; interferon regulatory factor 2-binding protein
C 484433 IRF2BP1; interferon regulatory factor 2-binding protein 1 K22383 IRF2BP; interferon regulatory factor 2-binding protein
B UBL E3 ligases
C 474494 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X2 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 481577 TOPORS; E3 ubiquitin-protein ligase Topors isoform X1 K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
C 474539 RANBP2; E3 SUMO-protein ligase RanBP2 isoform X1 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C 478350 PIAS1; E3 SUMO-protein ligase PIAS1 isoform X2 K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C 480147 PIAS2; E3 SUMO-protein ligase PIAS2 isoform X3 K16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]
C 483160 PIAS3; E3 SUMO-protein ligase PIAS3 isoform X2 K16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]
C 485049 PIAS4; E3 SUMO-protein ligase PIAS4 isoform X3 K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
C 487641 PML; protein PML isoform X1 K10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]
C 608556 CBX4; E3 SUMO-protein ligase CBX4 K11452 CBX4; E3 SUMO-protein ligase CBX4 [EC:2.3.2.-]
C 475096 NSMCE2; E3 SUMO-protein ligase NSE2 isoform X1 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C 102157290 RNF212; probable E3 SUMO-protein ligase RNF212 isoform X3 K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C 480249 RNF212B; RING finger protein 212B isoform X1 K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C 491715 ZBED1; E3 SUMO-protein ligase ZBED1 K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 474949 ZNF451; E3 SUMO-protein ligase ZNF451 isoform X1 K25176 ZNF451; E3 SUMO-protein ligase ZNF451 [EC:2.3.2.-]
C 478474 HERC5; E3 ISG15--protein ligase HERC5 isoform X1 K22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]
C 609237 HERC6; probable E3 ubiquitin-protein ligase HERC6 isoform X6 K22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]
C 474999 UFL1; E3 UFM1-protein ligase 1 isoform X1 K22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]
C 476997 DCUN1D2; DCN1-like protein 2 isoform X6 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 606979 DCUN1D1; DCN1-like protein 1 isoform X3 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 489983 DCUN1D3; DCN1-like protein 3 K17823 DCUN1D3; DCN1-like protein 3
C 487862 DCUN1D5; DCN1-like protein 5 isoform X2 K17824 DCUN1D4_5; DCN1-like protein 4/5
C 611020 DCUN1D4; DCN1-like protein 4 isoform X2 K17824 DCUN1D4_5; DCN1-like protein 4/5
C 102155691 DCN1-like protein 5 K17824 DCUN1D4_5; DCN1-like protein 4/5
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E 474494 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X2 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 475512 CUL1; cullin-1 K03347 CUL1; cullin 1
D Adaptor protein
E 474682 SKP1; S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
E 111090648 S-phase kinase-associated protein 1-like K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E 479291 FBXW11; F-box/WD repeat-containing protein 11 isoform X5 K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 486851 BTRC; F-box/WD repeat-containing protein 1A isoform X2 K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 610990 FBXW2; LOW QUALITY PROTEIN: F-box/WD repeat-containing protein 2 isoform X6 K10261 FBXW2; F-box and WD-40 domain protein 2
E 486852 FBXW4; F-box/WD repeat-containing protein 4 isoform X2 K10262 FBXW4; F-box and WD-40 domain protein 4
E 491243 FBXW5; F-box/WD repeat-containing protein 5 isoform X1 K10263 FBXW5; F-box and WD-40 domain protein 5
E 475465 FBXW7; F-box/WD repeat-containing protein 7 isoform X4 K10260 FBXW7; F-box and WD-40 domain protein 7
E 106557503 FBXW8; F-box/WD repeat-containing protein 8 K10264 FBXW8; F-box and WD-40 domain protein 8
E 476701 FBXW9; F-box/WD repeat-containing protein 9 isoform X2 K10265 FBXW9; F-box and WD-40 domain protein 9
E 479512 CDRT1; CMT1A duplicated region transcript 1 protein isoform X2 K10266 FBXW10; F-box and WD-40 domain protein 10
E 484779 FBXW12; F-box/WD repeat-containing protein 12 isoform X1 K10267 FBXW12S; F-box and WD-40 domain protein 12/13/14/15/16/17/19
E 489228 SKP2; S-phase kinase-associated protein 2 isoform X5 K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
E 485573 FBXL2; F-box/LRR-repeat protein 2 isoform X7 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 612832 FBXL20; F-box/LRR-repeat protein 20 isoform X1 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 485499 FBXL3; F-box/LRR-repeat protein 3 isoform X1 K10269 FBXL3; F-box and leucine-rich repeat protein 3
E 481932 FBXL4; F-box/LRR-repeat protein 4 K10270 FBXL4; F-box and leucine-rich repeat protein 4
E 479085 FBXL5; F-box/LRR-repeat protein 5 isoform X10 K10271 FBXL5; F-box and leucine-rich repeat protein 5
E 482094 FBXL6; F-box/LRR-repeat protein 6 isoform X2 K10272 FBXL6; F-box and leucine-rich repeat protein 6
E 489262 FBXL7; F-box/LRR-repeat protein 7 isoform X1 K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 611261 FBXL8; F-box/LRR-repeat protein 8 K10274 FBXL8; F-box and leucine-rich repeat protein 8
E 486262 KDM2B; lysine-specific demethylase 2B isoform X4 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 483702 KDM2A; lysine-specific demethylase 2A isoform X1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 484965 FBXL12; F-box/LRR-repeat protein 12 K10278 FBXL12; F-box and leucine-rich repeat protein 12
E 609997 FBXL13; dynein regulatory complex subunit 6 isoform X1 K10279 FBXL13; dynein regulatory complex subunit 6
E 486755 FBXL14; F-box/LRR-repeat protein 14 isoform X4 K10280 FBXL14; F-box and leucine-rich repeat protein 14
E 100855612 FBXL15; F-box/LRR-repeat protein 15 K10281 FBXL15; F-box and leucine-rich repeat protein 15
E 490090 FBXL16; F-box/LRR-repeat protein 16 isoform X1 K10282 FBXL16; F-box and leucine-rich repeat protein 16
E 608166 FBXL17; LOW QUALITY PROTEIN: F-box/LRR-repeat protein 17 isoform X1 K10283 FBXL17; F-box and leucine-rich repeat protein 17
E 489881 FBXL18; F-box/LRR-repeat protein 18 isoform X2 K10284 FBXL18; F-box and leucine-rich repeat protein 18
E 100856520 FBXL19; F-box/LRR-repeat protein 19 isoform X3 K10285 FBXL19; F-box and leucine-rich repeat protein 19
E 610104 FBXL21P; LOW QUALITY PROTEIN: F-box/LRR-repeat protein 21 isoform X1 K10287 FBXL21; F-box and leucine-rich repeat protein 21
E 610651 FBXL22; F-box and leucine-rich protein 22 K10288 FBXL22; F-box and leucine-rich repeat protein 22
E 610890 CCNF; cyclin-F isoform X1 K10289 CCNF; F-box protein 1 (cyclin F)
E 478231 FBXO2; F-box only protein 2 isoform X1 K10099 FBXO2; F-box protein 2
E 475944 FBXO3; F-box only protein 3 K10290 FBXO3; F-box protein 3
E 100856557 FBXO4; F-box only protein 4 isoform X1 K10291 FBXO4; F-box protein 4
E 612020 FBXO5; F-box only protein 5 isoform X2 K10292 FBXO5; F-box protein 5
E 487444 FBXO6; F-box only protein 6 K10100 FBXO6; F-box protein 6
E 474522 FBXO7; F-box only protein 7 isoform X2 K10293 FBXO7; F-box protein 7
E 477359 FBXO8; F-box only protein 8 K10294 FBXO8; F-box protein 8
E 474940 FBXO9; F-box only protein 9 K10295 FBXO9; F-box protein 9
E 481363 FBXO11; F-box only protein 11 K10297 FBXO11; F-box protein 11
E 100685224 FBXO15; F-box only protein 15 isoform X4 K10298 FBXO15; F-box protein 15
E 102155575 F-box only protein 16-like K10299 FBXO16; F-box protein 16
E 608213 FBXO16; F-box only protein 16 isoform X1 K10299 FBXO16; F-box protein 16
E 484516 FBXO17; F-box only protein 17 K10101 FBXO17; F-box protein 17
E 487142 FBH1; F-box DNA helicase 1 isoform X2 K10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4]
E 476948 LMO7; LIM domain only protein 7 isoform X1 K06084 LMO7; F-box protein 20
E 486290 FBXO21; F-box only protein 21 isoform X1 K10301 FBXO21; F-box protein 21
E 487672 FBXO22; F-box only protein 22 isoform X1 K10302 FBXO22; F-box protein 22
E 489098 TSPAN17; tetraspanin-17 isoform X5 K10303 FBXO23; F-box protein 23
E 608428 FBXO24; F-box only protein 24 isoform X2 K10304 FBXO24; F-box protein 24
E 608099 FBXO25; F-box only protein 25 isoform X1 K10305 FBXO25_32; F-box protein 25/32
E 475091 FBXO32; F-box only protein 32 K10305 FBXO25_32; F-box protein 25/32
E 484515 FBXO27; F-box only protein 27 K10102 FBXO27; F-box protein 27
E 612012 FBXO28; F-box only protein 28 K10306 FBXO28; F-box protein 28
E 484023 FBXO30; F-box only protein 30 K10307 FBXO30; F-box protein 30
E 479620 FBXO31; F-box only protein 31 isoform X1 K10308 FBXO31; F-box protein 31
E 490663 FBXO33; F-box only protein 33 K10310 FBXO33; F-box protein 33
E 490703 FBXO34; F-box only protein 34 K10311 FBXO34; F-box protein 34
E 100686210 FBXO36; F-box only protein 36 isoform X3 K10312 FBXO36; F-box protein 36
E 489199 FBXO38; F-box only protein 38 isoform X1 K10313 FBXO38; F-box protein 38
E 488004 FBXO40; F-box only protein 40 K10315 FBXO40; F-box protein 40
E 483113 FBXO41; F-box only protein 41 K10316 FBXO41; F-box protein 41
E 478219 FBXO42; F-box only protein 42 isoform X5 K10317 FBXO42; F-box protein 42
E 481982 FBXO43; LOW QUALITY PROTEIN: F-box only protein 43 isoform X2 K10318 FBXO43; F-box protein 43
E 487445 FBXO44; F-box only protein 44 isoform X1 K10103 FBXO44; F-box protein 44
E 488031 FBXO45; F-box/SPRY domain-containing protein 1 K10319 FBXO45; F-box protein 45
E 612248 FBXO46; F-box only protein 46 K10320 FBXO46; F-box protein 46
E 100683516 FBXO47; F-box only protein 47 isoform X1 K10321 FBXO47; F-box protein 47
E 100684024 FBXO48; F-box only protein 48 K27313 FBXO48; F-box protein 48
C Cul2 complex
D Ring finger protein
E 474494 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X2 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 477952 CUL2; cullin-2 isoform X1 K03870 CUL2; cullin 2
D Adoptor protein
E 477914 ELOC; elongin-C K03872 ELOC; elongin-C
E 119866339 elongin-C-like K03872 ELOC; elongin-C
E 119870849 elongin-C-like K03872 ELOC; elongin-C
E 479873 ELOB; elongin-B isoform X1 K03873 ELOB; elongin-B
D Target recognizing subunit
E 494000 VHL; von Hippel-Lindau disease tumor suppressor K03871 VHL; von Hippel-Lindau disease tumor supressor
E 490676 LRR1; leucine-rich repeat protein 1 isoform X2 K10348 LRR1; LRR-repeat protein 1
E 481437 FEM1C; protein fem-1 homolog C K25805 FEM1A_C; protein fem-1 homolog A/C
E 485032 FEM1A; protein fem-1 homolog A isoform X5 K25805 FEM1A_C; protein fem-1 homolog A/C
E 478352 FEM1B; protein fem-1 homolog B isoform X2 K10349 FEM1B; protein fem-1 homolog B
E 480588 APPBP2; amyloid protein-binding protein 2 K25806 APPBP2; amyloid protein-binding protein 2
E 480314 KLHDC2; kelch domain-containing protein 2 isoform X2 K25807 KLHDC2; kelch domain-containing protein 2
E 474907 KLHDC3; kelch domain-containing protein 3 isoform X1 K25808 KLHDC3; kelch domain-containing protein 3
E 475195 KLHDC10; kelch domain-containing protein 10 K25809 KLHDC10; kelch domain-containing protein 10
E 610740 ZYG11A; protein zyg-11 homolog A isoform X2 K10350 ZYG11; Zyg-11 protein
E 491312 ZER1; protein zer-1 homolog isoform X2 K10350 ZYG11; Zyg-11 protein
E 482495 ZYG11B; protein zyg-11 homolog B isoform X2 K10350 ZYG11; Zyg-11 protein
E 100856202 ZSWIM8; zinc finger SWIM domain-containing protein 8 isoform X3 K25207 ZSWIM8; zinc finger SWIM domain-containing protein 8
C Cul3 complex
D Ring finger protein
E 474494 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X2 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 477392 CUL3; cullin-3 isoform X5 K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E 485487 KLHL1; kelch-like protein 1 isoform X1 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 491999 KLHL4; kelch-like protein 4 isoform X2 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 612886 KLHL5; kelch-like protein 5 isoform X3 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 475490 KLHL2; kelch-like protein 2 isoform X1 K10443 KLHL2_3; kelch-like protein 2/3
E 481523 KLHL3; kelch-like protein 3 isoform X1 K10443 KLHL2_3; kelch-like protein 2/3
E 488096 KLHL6; kelch-like protein 6 isoform X1 K10444 KLHL6; kelch-like protein 6
E 475255 KLHL7; kelch-like protein 7 isoform X1 K10445 KLHL7; kelch-like protein 7
E 487847 KLHL8; kelch-like protein 8 isoform X1 K10446 KLHL8; kelch-like protein 8
E 492088 KLHL13; kelch-like protein 13 isoform X7 K10447 KLHL9_13; kelch-like protein 9/13
E 100688162 KLHL9; kelch-like protein 9 K10447 KLHL9_13; kelch-like protein 9/13
E 480521 KLHL10; kelch-like protein 10 isoform X2 K10448 KLHL10; kelch-like protein 10
E 480520 KLHL11; kelch-like protein 11 isoform X2 K10449 KLHL11; kelch-like protein 11
E 479996 KLHL12; kelch-like protein 12 K10450 KLHL12; kelch-like protein 12
E 490494 KLHL14; kelch-like protein 14 isoform X2 K10451 KLHL14; kelch-like protein 14
E 489694 GAN; gigaxonin isoform X4 K10453 KLHL16; kelch-like protein 16 (gigaxonin)
E 489607 KLHL17; kelch-like protein 17 isoform X2 K10454 KLHL17; kelch-like protein 17 (actinfilin)
E 484783 KLHL18; kelch-like protein 18 isoform X1 K10455 KLHL18; kelch-like protein 18
E 476713 KEAP1; kelch-like ECH-associated protein 1 K10456 KLHL19; kelch-like protein 19
E 480067 KLHL20; kelch-like protein 20 K10457 KLHL20; kelch-like protein 20
E 489634 KLHL21; kelch-like protein 21 K10458 KLHL21; kelch-like protein 21
E 486433 KLHL22; kelch-like protein 22 K10459 KLHL22; kelch-like protein 22
E 488392 KLHL23; kelch-like protein 23 K10460 KLHL23; kelch-like protein 23
E 478647 KLHL24; kelch-like protein 24 isoform X1 K10461 KLHL24_35; kelch-like protein 24/35
E 609209 KLHL35; kelch-like protein 35 K10461 KLHL24_35; kelch-like protein 24/35
E 488725 KLHL25; kelch-like protein 25 K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E 487247 ENC1; ectoderm-neural cortex protein 1 K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E 484817 KLHL26; kelch-like protein 26 isoform X31 K10463 KLHL26; kelch-like protein 26
E 475371 IPP; actin-binding protein IPP isoform X1 K13956 IPP; actin-binding protein IPP
E 490668 KLHL28; kelch-like protein 28 isoform X2 K10464 KLHL28; kelch-like protein 28
E 482991 KLHL29; kelch-like protein 29 K10465 KLHL29; kelch-like protein 29
E 607240 KLHL30; kelch-like protein 30 K10466 KLHL30; kelch-like protein 30
E 481846 KLHL31; kelch-like protein 31 K10467 KLHL31; kelch-like protein 31
E 481929 KLHL32; kelch-like protein 32 isoform X7 K10468 KLHL32; kelch-like protein 32
E 482556 KLHL33; kelch-like protein 33 isoform X5 K13957 KLHL33; kelch-like protein 33
E 489679 KLHL36; kelch-like protein 36 K13958 KLHL36; kelch-like protein 36
E 609348 KLHL38; kelch-like protein 38 K13959 KLHL38; kelch-like protein 38
E 119863910 kelch repeat and BTB domain-containing protein 2 K10470 KBTBD2; kelch repeat and BTB domain-containing protein 2
E 479456 KBTBD3; kelch repeat and BTB domain-containing protein 3 isoform X3 K10471 KBTBD3; kelch repeat and BTB domain-containing protein 3
E 483621 KBTBD4; kelch repeat and BTB domain-containing protein 4 isoform X3 K10472 KBTBD4; kelch repeat and BTB domain-containing protein 4
E 485616 KLHL40; kelch-like protein 40 K10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5/10
E 478784 KLHL41; kelch-like protein 41 K10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5/10
E 485467 KBTBD7; kelch repeat and BTB domain-containing protein 7 K10474 KBTBD6_7; kelch repeat and BTB domain-containing protein 6/7
E 102153124 KBTBD6; kelch repeat and BTB domain-containing protein 6 isoform X1 K10474 KBTBD6_7; kelch repeat and BTB domain-containing protein 6/7
E 106557453 KBTBD8; kelch repeat and BTB domain-containing protein 8 isoform X1 K10475 KBTBD8; kelch repeat and BTB domain-containing protein 8
E 491445 KBTBD11; kelch repeat and BTB domain-containing protein 11 isoform X1 K10476 KBTBD11; kelch repeat and BTB domain-containing protein 11
E 484625 KBTBD12; kelch repeat and BTB domain-containing protein 12 isoform X2 K21912 KBTBD12; kelch repeat and BTB domain-containing protein 12
E 102156878 KBTBD13; kelch repeat and BTB domain-containing protein 13 isoform X1 K21913 KBTBD13; kelch repeat and BTB domain-containing protein 13
E 479057 BTBD1; BTB/POZ domain-containing protein 1 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 485074 BTBD2; BTB/POZ domain-containing protein 2 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 477154 BTBD3; BTB/POZ domain-containing protein 3 isoform X2 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 102152663 BTBD6; BTB/POZ domain-containing protein 6 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 490834 BTBD7; BTB/POZ domain-containing protein 7 isoform X1 K10479 BTBD7; BTB/POZ domain-containing protein 7
E 612373 BTBD8; BTB/POZ domain-containing protein 8 isoform X6 K10480 BTBD8; BTB/POZ domain-containing protein 8
E 481777 BTBD9; BTB/POZ domain-containing protein 9 isoform X1 K10481 BTBD9; BTB/POZ domain-containing protein 9
E 476861 BTBD10; BTB/POZ domain-containing protein 10 isoform X2 K10482 BTBD10; BTB/POZ domain-containing protein 10
E 481292 BTBD11; ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform X8 K10483 BTBD11; BTB/POZ domain-containing protein 11
E 479867 SLX4; structure-specific endonuclease subunit SLX4 K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
E 481414 GMCL1; germ cell-less protein-like 1 isoform X2 K10485 BTBD13; BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1)
E 491255 NACC2; nucleus accumbens-associated protein 2 isoform X1 K10486 BTBD14; BTB/POZ domain-containing protein 14
E 484918 NACC1; nucleus accumbens-associated protein 1 isoform X1 K10486 BTBD14; BTB/POZ domain-containing protein 14
E 486920 BTBD16; BTB/POZ domain-containing protein 16 isoform X2 K10487 BTBD16; BTB/POZ domain-containing protein 16
E 490731 ZBTB1; zinc finger and BTB domain-containing protein 1 isoform 2 K10488 ZBTB1; zinc finger and BTB domain-containing protein 1
E 484036 ZBTB2; zinc finger and BTB domain-containing protein 2 K10489 ZBTB2; zinc finger and BTB domain-containing protein 2
E 483781 ZBTB3; zinc finger and BTB domain-containing protein 3 K10490 ZBTB3; zinc finger and BTB domain-containing protein 3
E 489474 ZBTB4; zinc finger and BTB domain-containing protein 4 K10491 ZBTB4; zinc finger and BTB domain-containing protein 4
E 481612 ZBTB5; zinc finger and BTB domain-containing protein 5 isoform X2 K10492 ZBTB5; zinc finger and BTB domain-containing protein 5
E 491343 ZBTB6; zinc finger and BTB domain-containing protein 6 isoform X1 K10493 ZBTB6; zinc finger and BTB domain-containing protein 6
E 490573 ZBTB7C; zinc finger and BTB domain-containing protein 7C K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E 485048 ZBTB7A; zinc finger and BTB domain-containing protein 7A K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E 490437 ZBTB7B; zinc finger and BTB domain-containing protein 7B isoform X1 K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E 487304 ZBTB8A; zinc finger and BTB domain-containing protein 8A K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
E 487306 ZBTB8B; zinc finger and BTB domain-containing protein 8B isoform X1 K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
E 100688678 ZBTB9; LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 9 K10496 ZBTB9; zinc finger and BTB domain-containing protein 9
E 487014 ZBTB10; zinc finger and BTB domain-containing protein 10 isoform X1 K10497 ZBTB10; zinc finger and BTB domain-containing protein 10
E 487956 ZBTB11; zinc finger and BTB domain-containing protein 11 isoform X2 K10498 ZBTB11; zinc finger and BTB domain-containing protein 11
E 481719 ZBTB12; zinc finger and BTB domain-containing protein 12 K10499 ZBTB12; zinc finger and BTB domain-containing protein 12
E 489398 ZBTB16; zinc finger and BTB domain-containing protein 16 K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
E 607083 ZBTB17; zinc finger and BTB domain-containing protein 17 isoform X1 K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
E 607900 ZBTB22; zinc finger and BTB domain-containing protein 22 K10502 ZBTB22; zinc finger and BTB domain-containing protein 22
E 475021 ZBTB24; zinc finger and BTB domain-containing protein 24 isoform X23 K10503 ZBTB24; zinc finger and BTB domain-containing protein 24
E 490730 ZBTB25; zinc finger and BTB domain-containing protein 25 isoform X1 K10504 ZBTB25; zinc finger and BTB domain-containing protein 25
E 491342 ZBTB26; zinc finger and BTB domain-containing protein 26 K10505 ZBTB26; zinc finger and BTB domain-containing protein 26
E 484577 ZBTB32; zinc finger and BTB domain-containing protein 32 isoform X9 K10506 ZBTB32; zinc finger and BTB domain-containing protein 32
E 100685062 ZBTB33; transcriptional regulator Kaiso K10507 ZBTB33; zinc finger and BTB domain-containing protein 33
E 491331 ZBTB34; zinc finger and BTB domain-containing protein 34 K10508 ZBTB34; zinc finger and BTB domain-containing protein 34
E 490336 ZBTB37; zinc finger and BTB domain-containing protein 37 isoform X2 K10509 ZBTB37; zinc finger and BTB domain-containing protein 37
E 477096 ZBTB38; zinc finger and BTB domain-containing protein 38 isoform X1 K10510 ZBTB38; zinc finger and BTB domain-containing protein 38
E 481121 ZBTB39; zinc finger and BTB domain-containing protein 39 K10511 ZBTB39; zinc finger and BTB domain-containing protein 39
E 487384 ZBTB40; zinc finger and BTB domain-containing protein 40 isoform X5 K10512 ZBTB40; zinc finger and BTB domain-containing protein 40
E 612864 ZBTB41; zinc finger and BTB domain-containing protein 41 K10513 ZBTB41; zinc finger and BTB domain-containing protein 41
E 612870 ZBTB43; zinc finger and BTB domain-containing protein 43 K10514 ZBTB43; zinc finger and BTB domain-containing protein 43
E 489277 ZBTB44; zinc finger and BTB domain-containing protein 44 isoform X1 K10515 ZBTB44; zinc finger and BTB domain-containing protein 44
E 484222 ZBTB45; zinc finger and BTB domain-containing protein 45 isoform X1 K10516 ZBTB45; zinc finger and BTB domain-containing protein 45
E 485980 ZBTB46; zinc finger and BTB domain-containing protein 46 isoform X2 K10517 ZBTB46; zinc finger and BTB domain-containing protein 46
E 100686908 ZBTB47; zinc finger and BTB domain-containing protein 47 isoform X1 K10518 ZBTB47; zinc finger and BTB domain-containing protein 47
E 608070 ZBTB48; telomere zinc finger-associated protein K10519 ZBTB48; zinc finger and BTB domain-containing protein 48
E 609299 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1 isoform X1 K10520 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1
E 483430 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2 isoform X2 K10521 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2
E 488998 RHOBTB1; rho-related BTB domain-containing protein 1 isoform X1 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 100856331 RHOBTB2; rho-related BTB domain-containing protein 2 isoform X3 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 100687706 RHOBTB3; rho-related BTB domain-containing protein 3 isoform X1 K07869 RHOBTB3; Rho-related BTB domain-containing protein 3
E 486312 KCTD10; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 isoform X1 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 491161 TNFAIP1; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 489942 KCTD13; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 isoform X2 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 480170 KCTD1; BTB/POZ domain-containing protein KCTD1 isoform X2 K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 484595 KCTD15; BTB/POZ domain-containing protein KCTD15 K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 481274 KCTD17; LOW QUALITY PROTEIN: BTB/POZ domain-containing protein KCTD17 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 490058 KCTD5; BTB/POZ domain-containing protein KCTD5 isoform X2 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 609652 KCTD2; BTB/POZ domain-containing protein KCTD2 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 478960 KCTD3; BTB/POZ domain-containing protein KCTD3 isoform X1 K21915 KCTD3; BTB/POZ domain-containing protein KCTD3
E 100855620 KCTD6; BTB/POZ domain-containing protein KCTD6 isoform X1 K21916 KCTD6; BTB/POZ domain-containing protein KCTD6
E 485170 KCTD14; BTB/POZ domain-containing protein KCTD14 K21917 KCTD7_14; BTB/POZ domain-containing protein KCTD7/14
E 479706 RABGEF1; rab5 GDP/GTP exchange factor isoform X3 K21917 KCTD7_14; BTB/POZ domain-containing protein KCTD7/14
E 119872131 KCTD7; BTB/POZ domain-containing protein KCTD7 isoform X1 K21917 KCTD7_14; BTB/POZ domain-containing protein KCTD7/14
E 485495 KCTD12; BTB/POZ domain-containing protein KCTD12 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 487196 KCTD16; BTB/POZ domain-containing protein KCTD16 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 610705 KCTD8; LOW QUALITY PROTEIN: BTB/POZ domain-containing protein KCTD8 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 486109 KCTD9; BTB/POZ domain-containing protein KCTD9 K21919 KCTD9; BTB/POZ domain-containing protein KCTD9
E 607761 KCTD11; BTB/POZ domain-containing protein KCTD11 K21920 KCTD11; BTB/POZ domain-containing protein KCTD11 [EC:2.3.2.27]
E 488464 KCTD18; BTB/POZ domain-containing protein KCTD18 isoform X1 K21921 KCTD18; BTB/POZ domain-containing protein KCTD18
E 608875 KCTD21; BTB/POZ domain-containing protein KCTD21 K21922 KCTD21; BTB/POZ domain-containing protein KCTD21
E 477463 DIABLO; diablo homolog, mitochondrial K10522 DIABLO; diablo
E 480548 SPOP; speckle-type POZ protein K10523 SPOP; speckle-type POZ protein
E 476134 SPOPL; speckle-type POZ protein-like isoform X1 K10523 SPOP; speckle-type POZ protein
E 608108 LZTR1; leucine-zipper-like transcriptional regulator 1 isoform X1 K23330 LZTR1; leucine-zipper-like transcriptional regulator 1
C Cul4 complex
D Ring finger protein
E 474494 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X2 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 492102 CUL4B; cullin-4B isoform X3 K10609 CUL4; cullin 4
E 607683 CUL4A; cullin-4A isoform X5 K10609 CUL4; cullin 4
D Adoptor protein
E 476067 DDB1; DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E 483626 DDB2; DNA damage-binding protein 2 isoform X1 K10140 DDB2; DNA damage-binding protein 2
E 487225 ERCC8; DNA excision repair protein ERCC-8 isoform X3 K10570 ERCC8; DNA excision repair protein ERCC-8
E 479036 DET1; DET1 homolog isoform X2 K10571 DET1; de-etiolated-1
E 480060 COP1; E3 ubiquitin-protein ligase COP1 isoform X6 K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
E 476675 DDA1; DET1- and DDB1-associated protein 1 isoform X5 K11792 DDA1; DET1- and DDB1-associated protein 1
E 476551 CRBN; protein cereblon isoform X2 K11793 CRBN; cereblon
E 610310 torsin-1A-interacting protein 2 K11794 IFRG15; IFRG15 protein
E 477207 TRPC4AP; short transient receptor potential channel 4-associated protein isoform X1 K11796 TRPC4AP; Trpc4-associated protein
E 100855502 DCAF1; DDB1- and CUL4-associated factor 1 isoform X1 K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
E 490279 DTL; denticleless protein homolog isoform X1 K11790 DTL; denticleless
E 490767 DCAF4; DDB1- and CUL4-associated factor 4 isoform X1 K11799 DCAF4; DDB1- and CUL4-associated factor 4
E 490749 DCAF5; DDB1- and CUL4-associated factor 5 isoform X2 K11800 DCAF5; DDB1- and CUL4-associated factor 5
E 480085 DCAF6; DDB1- and CUL4-associated factor 6 isoform X1 K11795 DCAF6; DDB1- and CUL4-associated factor 6
E 100856670 DCAF7; DDB1- and CUL4-associated factor 7 K11805 DCAF7; DDB1- and CUL4-associated factor 7
E 478971 DCAF8; DDB1- and CUL4-associated factor 8 K11804 DCAF8; DDB1- and CUL4-associated factor 8
E 491793 DDB1- and CUL4-associated factor 8 K11804 DCAF8; DDB1- and CUL4-associated factor 8
E 487347 WDTC1; WD and tetratricopeptide repeats protein 1 isoform X1 K11807 WDTC1; WD and tetratricopeptide repeats protein 1
E 481617 DCAF10; DDB1- and CUL4-associated factor 10 K11802 DCAF10; DDB1- and CUL4-associated factor 10
E 490621 DCAF11; DDB1- and CUL4-associated factor 11 isoform X1 K11801 DCAF11; DDB1- and CUL4-associated factor 11
E 481584 DCAF12; DDB1- and CUL4-associated factor 12 isoform X3 K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 492114 DDB1- and CUL4-associated factor 12-like protein 2 K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 609540 DDB1- and CUL4-associated factor 12-like protein 2 K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 475065 DCAF13; DDB1- and CUL4-associated factor 13 isoform X2 K11806 DCAF13; DDB1- and CUL4-associated factor 13
E 474976 PHIP; PH-interacting protein isoform X3 K11797 PHIP; PH-interacting protein
E 484909 DCAF15; DDB1- and CUL4-associated factor 15 K11791 DCAF15; DDB1- and CUL4-associated factor 15
E 102156727 DCAF16; DDB1- and CUL4-associated factor 16 K23626 DCAF16; DDB1- and CUL4-associated factor 16
E 609326 DCAF17; DDB1- and CUL4-associated factor 17 isoform X1 K23331 DCAF17; DDB1- and CUL4-associated factor 17
E 491984 BRWD3; bromodomain and WD repeat-containing protein 3 isoform X1 K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 487764 BRWD1; bromodomain and WD repeat-containing protein 1 isoform X2 K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 480115 WDR26; WD repeat-containing protein 26 isoform X1 K22382 WDR26; WD repeat-containing protein 26
E 489225 WDR70; WD repeat-containing protein 70 isoform X3 K24752 WDR70; WD repeat-containing protein 70
E 487529 WDR76; WD repeat-containing protein 76 isoform X3 K24755 WDR76; WD repeat-containing protein 76
C Cul5 complex
D Ring finger protein
E 106557459 RNF7; RING-box protein 2 isoform X1 K10611 RBX2; RING-box protein 2
D Cullin
E 489422 CUL5; LOW QUALITY PROTEIN: cullin-5 K10612 CUL5; cullin 5
D Adoptor protein
E 477914 ELOC; elongin-C K03872 ELOC; elongin-C
E 119866339 elongin-C-like K03872 ELOC; elongin-C
E 119870849 elongin-C-like K03872 ELOC; elongin-C
E 479873 ELOB; elongin-B isoform X1 K03873 ELOB; elongin-B
D Target recognizing subunit
E 484757 CISH; cytokine-inducible SH2-containing protein K04701 CISH; cytokine inducible SH2-containing protein
E 490006 SOCS1; suppressor of cytokine signaling 1 K04694 SOCS1; suppressor of cytokine signaling 1
E 100855737 SOCS2; suppressor of cytokine signaling 2 isoform X3 K04695 SOCS2; suppressor of cytokine signaling 2
E 442949 SOCS3; suppressor of cytokine signaling 3 K04696 SOCS3; suppressor of cytokine signaling 3
E 100687271 SOCS4; suppressor of cytokine signaling 4 K04697 SOCS4; suppressor of cytokine signaling 4
E 474581 SOCS5; suppressor of cytokine signaling 5 K04698 SOCS5; suppressor of cytokine signaling 5
E 491039 SOCS7; suppressor of cytokine signaling 7 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 100856303 SOCS6; suppressor of cytokine signaling 6 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 100684658 LOW QUALITY PROTEIN: suppressor of cytokine signaling 6-like K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 490836 ASB2; ankyrin repeat and SOCS box protein 2 isoform X2 K10324 ASB2; ankyrin repeat and SOCS box protein 2
E 474592 ASB3; ankyrin repeat and SOCS box protein 3 K10325 ASB3; ankyrin repeat and SOCS box protein 3
E 482309 ASB4; ankyrin repeat and SOCS box protein 4 isoform X1 K10326 ASB4; ankyrin repeat and SOCS box protein 4
E 482933 ASB5; ankyrin repeat and SOCS box protein 5 isoform X12 K10327 ASB5; ankyrin repeat and SOCS box protein 5
E 491299 ASB6; ankyrin repeat and SOCS box protein 6 isoform X2 K10328 ASB6; ankyrin repeat and SOCS box protein 6
E 488707 ASB7; ankyrin repeat and SOCS box protein 7 K10329 ASB7; ankyrin repeat and SOCS box protein 7
E 486587 ASB8; ankyrin repeat and SOCS box protein 8 isoform X1 K10330 ASB8; ankyrin repeat and SOCS box protein 8
E 480845 ASB9; ankyrin repeat and SOCS box protein 9 isoform X3 K10331 ASB9; ankyrin repeat and SOCS box protein 9
E 482804 ASB10; ankyrin repeat and SOCS box protein 10 isoform X2 K10332 ASB10; ankyrin repeat and SOCS box protein 10
E 612782 ASB11; ankyrin repeat and SOCS box protein 11 isoform X1 K10333 ASB11; ankyrin repeat and SOCS box protein 11
E 480939 ASB12; ankyrin repeat and SOCS box protein 12 isoform X1 K10334 ASB12; ankyrin repeat and SOCS box protein 12
E 608587 ASB13; ankyrin repeat and SOCS box protein 13 isoform X1 K10335 ASB13; ankyrin repeat and SOCS box protein 13
E 607136 ASB14; ankyrin repeat and SOCS box protein 14 isoform X1 K10336 ASB14; ankyrin repeat and SOCS box protein 14
E 482279 ASB15; ankyrin repeat and SOCS box protein 15 isoform X8 K10337 ASB15; ankyrin repeat and SOCS box protein 15
E 490940 ASB16; ankyrin repeat and SOCS box protein 16 K10338 ASB16; ankyrin repeat and SOCS box protein 16
E 403539 ASB17; ankyrin repeat and SOCS box protein 17 K10339 ASB17; ankyrin repeat and SOCS box protein 17
E 486175 ASB18; ankyrin repeat and SOCS box protein 18 K10340 ASB18; ankyrin repeat and SOCS box protein 18
E 480619 WSB1; WD repeat and SOCS box-containing protein 1 isoform X3 K10341 WSB1; WD repeat and SOCS box-containing protein 1
E 477500 WSB2; WD repeat and SOCS box-containing protein 2 isoform X1 K10342 WSB2; WD repeat and SOCS box-containing protein 2
E 479598 SPSB1; SPRY domain-containing SOCS box protein 1 isoform X1 K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 485691 SPSB4; SPRY domain-containing SOCS box protein 4 isoform X1 K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 477710 SPSB2; SPRY domain-containing SOCS box protein 2 K10344 SPSB2; SPRY domain-containing SOCS box protein 2
E 490071 SPSB3; SPRY domain-containing SOCS box protein 3 isoform X1 K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 611450 RAB40C; ras-related protein Rab-40C isoform X1 K07928 RAB40; Ras-related protein Rab-40
E 608295 RAB40B; ras-related protein Rab-40B K07928 RAB40; Ras-related protein Rab-40
E 608535 LRRC41; leucine-rich repeat-containing protein 41 isoform X2 K10347 LRRC41; leucine-rich repeat-containing protein 41
E 478112 RSPRY1; RING finger and SPRY domain-containing protein 1 K23332 RSPRY1; RING finger and SPRY domain-containing protein 1
E 490865 ANKRD9; ankyrin repeat domain-containing protein 9 K25208 ANKRD9; ankyrin repeat domain-containing protein 9
E 490677 KLHDC1; kelch domain-containing protein 1 isoform X5 K25810 KLHDC1; kelch domain-containing protein 1
C Cul7 complex
D Ring finger protein
E 474494 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X2 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 481807 CUL7; cullin-7 isoform X1 K10613 CUL7; cullin 7
D Adaptor protein
E 474682 SKP1; S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
E 111090648 S-phase kinase-associated protein 1-like K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
E 106557503 FBXW8; F-box/WD repeat-containing protein 8 K10264 FBXW8; F-box and WD-40 domain protein 8
C Cul8 complex
D Ring finger protein
E 474494 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X2 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E 474494 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X2 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 481809 CUL9; cullin-9 isoform X3 K11970 CUL9; cullin 9
C APC/C
D Ring finger protein
E 483370 ANAPC11; anaphase-promoting complex subunit 11 K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
E 491236 ANAPC2; anaphase-promoting complex subunit 2 K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E 100855774 CDC20; cell division cycle protein 20 homolog K03363 CDC20; cell division cycle 20, cofactor of APC complex
E 485059 FZR1; fizzy-related protein homolog isoform X1 K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E 475750 ANAPC1; anaphase-promoting complex subunit 1 isoform X12 K03348 APC1; anaphase-promoting complex subunit 1
E 490924 CDC27; cell division cycle protein 27 homolog isoform X4 K03350 APC3; anaphase-promoting complex subunit 3
E 479123 ANAPC4; anaphase-promoting complex subunit 4 K03351 APC4; anaphase-promoting complex subunit 4
E 477471 ANAPC5; anaphase-promoting complex subunit 5 isoform X2 K03352 APC5; anaphase-promoting complex subunit 5
E 607100 CDC16; cell division cycle protein 16 homolog isoform X3 K03353 APC6; anaphase-promoting complex subunit 6
E 486264 ANAPC7; anaphase-promoting complex subunit 7 isoform X3 K03354 APC7; anaphase-promoting complex subunit 7
E 481526 CDC23; cell division cycle protein 23 homolog isoform X2 K03355 APC8; anaphase-promoting complex subunit 8
E 475453 ANAPC10; anaphase-promoting complex subunit 10 isoform X1 K03357 APC10; anaphase-promoting complex subunit 10
E 481679 CDC26; anaphase-promoting complex subunit CDC26 K03359 APC12; anaphase-promoting complex subunit 12
E 609033 ANAPC13; anaphase-promoting complex subunit 13 K12456 APC13; anaphase-promoting complex subunit 13
E 100685549 anaphase-promoting complex subunit 13-like K12456 APC13; anaphase-promoting complex subunit 13
E 102156563 anaphase-promoting complex subunit 13-like K12456 APC13; anaphase-promoting complex subunit 13
E 476817 ANAPC15; anaphase-promoting complex subunit 15 isoform X2 K25228 APC15; anaphase-promoting complex subunit 15
E 608342 ANAPC16; anaphase-promoting complex subunit 16 isoform X1 K25229 APC16; anaphase-promoting complex subunit 16
C BRCC complex
D 403437 BRCA1; breast cancer type 1 susceptibility protein homolog K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
D 474180 BRCA2; breast cancer type 2 susceptibility protein K08775 BRCA2; breast cancer 2 susceptibility protein
D 612642 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X4 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 610150 LOW QUALITY PROTEIN: lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 610190 BARD1; BRCA1-associated RING domain protein 1 isoform X1 K10683 BARD1; BRCA1-associated RING domain protein 1
D 102156002 LOW QUALITY PROTEIN: BRCA1-associated RING domain protein 1-like isoform X3 K10683 BARD1; BRCA1-associated RING domain protein 1
D 475711 BABAM2; BRISC and BRCA1-A complex member 2 isoform X2 K12173 BRE; BRCA1-A complex subunit BRE
D 403568 RAD51; DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51
C KPC complex
D 484767 RNF123; E3 ubiquitin-protein ligase RNF123 isoform X5 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 491256 UBAC1; ubiquitin-associated domain-containing protein 1 isoform X1 K12174 KPC2; Kip1 ubiquitination-promoting complex protein 2
C LUBAC complex
D 475122 sharpin K20894 SHARPIN; shank-associated RH domain-interacting protein
D 485818 RBCK1; ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X2 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 480259 RNF31; E3 ubiquitin-protein ligase RNF31 isoform X1 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
C CTLH complex
D 474643 RMND5B; E3 ubiquitin-protein transferase RMND5B isoform X1 K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 475760 RMND5A; E3 ubiquitin-protein transferase RMND5A isoform X1 K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 478728 RANBP9; LOW QUALITY PROTEIN: ran-binding protein 9 K23334 RANBP9_10; Ran-binding protein 9/10
D 489754 RANBP10; ran-binding protein 10 isoform X2 K23334 RANBP9_10; Ran-binding protein 9/10
D 485684 ARMC8; armadillo repeat-containing protein 8 K23336 ARMC8; armadillo repeat-containing protein 8
D 607643 MKLN1; muskelin isoform X1 K23337 MKLN1; muskelin
D 610745 MAEA; E3 ubiquitin-protein transferase MAEA isoform X1 K18624 MAEA; macrophage erythroblast attacher
D 479524 GID4; LOW QUALITY PROTEIN: glucose-induced degradation protein 4 homolog K23335 GID4; glucose-induced degradation protein 4
D 488056 GID8; glucose-induced degradation protein 8 homolog K23338 GID8; glucose-induced degradation protein 8
D 607847 LOW QUALITY PROTEIN: glucose-induced degradation protein 8 homolog K23338 GID8; glucose-induced degradation protein 8
D 475714 YPEL5; protein yippee-like 5 K23339 YPEL5; protein yippee-like 5
D 480115 WDR26; WD repeat-containing protein 26 isoform X1 K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
D 487269 AMFR; E3 ubiquitin-protein ligase AMFR isoform X3 K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 610957 TMUB1; transmembrane and ubiquitin-like domain-containing protein 1 K23340 TMUB; transmembrane and ubiquitin-like domain-containing protein
D 607070 TMUB2; transmembrane and ubiquitin-like domain-containing protein 2 isoform X1 K23340 TMUB; transmembrane and ubiquitin-like domain-containing protein
D 609141 ERLIN1; erlin-1 isoform X1 K23341 ERLIN; erlin
D 607518 ERLIN2; erlin-2 isoform X1 K23341 ERLIN; erlin
C LMBR1L-GP78-UBAC2 complex
D 612809 LMBR1L; protein LMBR1L isoform X2 K25215 LMBR1L; protein LMBR1L
D 487269 AMFR; E3 ubiquitin-protein ligase AMFR isoform X3 K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 608309 UBAC2; ubiquitin-associated domain-containing protein 2 isoform X2 K25216 UBAC2; ubiquitin-associated domain-containing protein 2
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D 474437 CAND1; cullin-associated NEDD8-dissociated protein 1 K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D 484646 CAND2; cullin-associated NEDD8-dissociated protein 2 isoform X2 K24172 CAND2; cullin-associated NEDD8-dissociated protein 2
D 403590 COMMD1; COMM domain-containing protein 1 K22557 COMMD1; COMM domain containing 1
D 485713 COMMD2; COMM domain-containing protein 2 K22558 COMMD2; COMM domain containing 2
D 477977 COMMD3; COMM domain-containing protein 3 K22559 COMMD3; COMM domain containing 3
D 612915 COMMD4; COMM domain-containing protein 4 K22560 COMMD4; COMM domain containing 4
D 482105 COMMD5; COMM domain-containing protein 5 K22561 COMMD5; COMM domain containing 5
D 476946 COMMD6; COMM domain-containing protein 6 isoform X2 K22562 COMMD6; COMM domain containing 6
D 612903 COMMD7; COMM domain-containing protein 7 isoform X1 K22563 COMMD7; COMM domain containing 7
D 475138 COMMD8; COMM domain-containing protein 8 K22564 COMMD8; COMM domain containing 8
D 608575 COMMD9; COMM domain-containing protein 9 K22565 COMMD9; COMM domain containing 9
D 474635 COMMD10; COMM domain-containing protein 10 isoform X2 K22566 COMMD10; COMM domain containing 10
D 491875 CCDC22; coiled-coil domain-containing protein 22 isoform X1 K23343 CCDC22; coiled-coil domain-containing protein 22
D 477173 DDRGK1; DDRGK domain-containing protein 1 isoform X1 K23344 DDRGK1; DDRGK domain-containing protein 1
D 479951 GLMN; glomulin K23345 GLMN; glomulin
D 480043 influenza virus NS1A-binding protein K15046 IVNS1ABP; influenza virus NS1A-binding protein
D 488028 UBXN7; UBX domain-containing protein 7 isoform X5 K24350 UBXN7; UBX domain-containing protein 7
D 484071 PACRG; parkin coregulated gene protein isoform X1 K26163 PACRG; parkin coregulated gene protein
D 481583 UBAP2; ubiquitin-associated protein 2 isoform X2 K26545 UBAP2; ubiquitin-associated protein 2
D 480135 UBAP2L; ubiquitin-associated protein 2-like isoform X62 K26545 UBAP2; ubiquitin-associated protein 2
#
ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D 479098 UCHL1; ubiquitin carboxyl-terminal hydrolase isozyme L1 K05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
D 484737 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 K08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
D 476947 UCHL3; ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X1 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D 478958 UCHL5; ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform X2 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D 611649 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD isoform X1 K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
D 479549 USP1; ubiquitin carboxyl-terminal hydrolase 1 isoform X1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D 608188 USP2; ubiquitin carboxyl-terminal hydrolase 2 isoform X1 K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D 487590 USP3; ubiquitin carboxyl-terminal hydrolase 3 isoform X1 K11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]
D 476624 USP4; ubiquitin carboxyl-terminal hydrolase 4 isoform X2 K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D 404014 USP11; ubiquitin carboxyl-terminal hydrolase 11 K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D 478640 USP13; ubiquitin carboxyl-terminal hydrolase 13 isoform X5 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 486718 USP5; ubiquitin carboxyl-terminal hydrolase 5 isoform X3 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 480590 USP32; ubiquitin carboxyl-terminal hydrolase 32 isoform X1 K11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12]
D 479854 USP7; ubiquitin carboxyl-terminal hydrolase 7 isoform X2 K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D 478299 USP8; ubiquitin carboxyl-terminal hydrolase 8 isoform X2 K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D 479558 USP24; ubiquitin carboxyl-terminal hydrolase 24 isoform X1 K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 480885 USP9X; probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X8 K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 479625 USP10; ubiquitin carboxyl-terminal hydrolase 10 K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D 475142 USP46; ubiquitin carboxyl-terminal hydrolase 46 isoform X1 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 486033 USP12; ubiquitin carboxyl-terminal hydrolase 12 isoform X3 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 480182 USP14; ubiquitin carboxyl-terminal hydrolase 14 isoform X2 K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D 474424 USP15; ubiquitin carboxyl-terminal hydrolase 15 isoform X5 K21343 USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]
D 481933 USP45; ubiquitin carboxyl-terminal hydrolase 45 isoform X12 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 478398 USP16; ubiquitin carboxyl-terminal hydrolase 16 isoform X4 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 482940 LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 17-like protein 6 isoform X3 K11845 USP17; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]
D 611374 ubiquitin carboxyl-terminal hydrolase 17-like K11845 USP17; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]
D 100688437 LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 17-like protein 6 isoform X2 K11845 USP17; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]
D 486763 USP18; ubl carboxyl-terminal hydrolase 18 isoform X1 K11846 USP18_41; ubiquitin carboxyl-terminal hydrolase 18/41 [EC:3.4.19.12]
D 476627 USP19; ubiquitin carboxyl-terminal hydrolase 19 isoform X1 K11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12]
D 480696 USP20; ubiquitin carboxyl-terminal hydrolase 20 K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 479984 USP33; ubiquitin carboxyl-terminal hydrolase 33 isoform X1 K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 478979 USP21; ubiquitin carboxyl-terminal hydrolase 21 K21634 USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]
D 609588 USP22; ubiquitin carboxyl-terminal hydrolase 22 isoform X1 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 100686687 USP27X; ubiquitin carboxyl-terminal hydrolase 27 isoform X3 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 100685592 USP51; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 51 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 478387 USP25; ubiquitin carboxyl-terminal hydrolase 25 isoform X3 K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
D 488523 USP37; ubiquitin carboxyl-terminal hydrolase 37 K11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12]
D 492143 USP26; ubiquitin carboxyl-terminal hydrolase 26 K11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12]
D 489400 USP28; ubiquitin carboxyl-terminal hydrolase 28 isoform X3 K21122 USP28; ubiquitin carboxyl-terminal hydrolase 28 [EC:3.4.19.12]
D 611662 USP30; ubiquitin carboxyl-terminal hydrolase 30 isoform X1 K11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]
D 100856211 USP31; ubiquitin carboxyl-terminal hydrolase 31 isoform X1 K11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]
D 474608 USP34; ubiquitin carboxyl-terminal hydrolase 34 isoform X1 K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
D 485168 USP35; ubiquitin carboxyl-terminal hydrolase 35 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 476071 USP38; ubiquitin carboxyl-terminal hydrolase 38 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 483344 USP36; ubiquitin carboxyl-terminal hydrolase 36 isoform X1 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D 479754 USP42; ubiquitin carboxyl-terminal hydrolase 42 isoform X2 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D 486168 USP40; ubiquitin carboxyl-terminal hydrolase 40 isoform X1 K11869 USP40; ubiquitin carboxyl-terminal hydrolase 40 [EC:3.4.19.12]
D 489498 USP43; ubiquitin carboxyl-terminal hydrolase 43 isoform X1 K11856 USP43; ubiquitin carboxyl-terminal hydrolase 43 [EC:3.4.19.12]
D 474899 USP49; ubiquitin carboxyl-terminal hydrolase 49 K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]
D 475430 USP44; ubiquitin carboxyl-terminal hydrolase 44 K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]
D 100684506 USP47; ubiquitin carboxyl-terminal hydrolase 47 isoform X10 K11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]
D 478198 USP48; ubiquitin carboxyl-terminal hydrolase 48 isoform X6 K11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]
C OTU
D 611228 OTUB1; ubiquitin thioesterase OTUB1 K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
D 480420 OTUB2; ubiquitin thioesterase OTUB2 isoform X2 K09603 OTUB2; ubiquitin thioesterase protein OTUB2 [EC:3.4.19.12]
D 100687506 OTUD3; OTU domain-containing protein 3 isoform X1 K13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]
D 480911 OTUD5; OTU domain-containing protein 5 isoform X1 K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
D 487042 OTUD6B; deubiquitinase OTUD6B isoform X3 K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 491937 OTUD6A; OTU domain-containing protein 6A K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 488697 OTUD7A; OTU domain-containing protein 7A K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
D 483178 OTUD7B; OTU domain-containing protein 7B isoform X2 K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
D 606770 OTULIN; ubiquitin thioesterase otulin isoform X1 K18343 OTULIN; ubiquitin thioesterase otulin [EC:3.4.19.12]
D 484006 TNFAIP3; tumor necrosis factor alpha-induced protein 3 isoform X2 K11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
D 486980 VCPIP1; deubiquitinating protein VCPIP1 K11861 VCPIP1; deubiquitinating protein VCIP135 [EC:3.4.19.12]
D 486931 ZRANB1; ubiquitin thioesterase ZRANB1 isoform X3 K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
C MJD
D 480229 ATXN3; LOW QUALITY PROTEIN: ataxin-3 K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
D 100687064 LOW QUALITY PROTEIN: ataxin-3 isoform X6 K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
D 481251 JOSD1; josephin-1 K15235 JOSD; josephin [EC:3.4.19.12]
D 611845 JOSD2; josephin-2 K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D 483188 MINDY1; ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform X2 K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
D 487577 MINDY2; ubiquitin carboxyl-terminal hydrolase MINDY-2 isoform X1 K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
D 487118 MINDY3; ubiquitin carboxyl-terminal hydrolase MINDY-3 isoform X3 K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 475269 MINDY4; probable ubiquitin carboxyl-terminal hydrolase MINDY-4 isoform X3 K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 102155588 MINDY4B; inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
C JAMM
D 612642 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X4 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 610150 LOW QUALITY PROTEIN: lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 489568 MYSM1; histone H2A deubiquitinase MYSM1 isoform X1 K11865 MYSM1; histone H2A deubiquitinase [EC:3.4.19.-]
D 485040 MPND; MPN domain-containing protein isoform X3 K24173 MPND; MPN domain-containing protein
D 478765 PSMD14; 26S proteasome non-ATPase regulatory subunit 14 K03030 PSMD14; 26S proteasome regulatory subunit N11
D 100684058 STAM-binding protein K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
D 477586 STAMBPL1; AMSH-like protease isoform X2 K11867 STAMBPL1; AMSH-like protease [EC:3.4.19.12]
C PPPDE
D 490377 DESI2; deubiquitinase DESI2 isoform X2 K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
D 476272 ZUP1; zinc finger-containing ubiquitin peptidase 1 isoform X1 K24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]
C BRISC complex
D 477859 ABRAXAS2; BRISC complex subunit Abraxas 2 isoform X5 K20799 FAM175B; BRISC complex subunit Abro1
D 476676 BABAM1; BRISC and BRCA1-A complex member 1 K20776 BABAM; BRISC and BRCA1-A complex member 1
D 612642 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X4 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 610150 LOW QUALITY PROTEIN: lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 475711 BABAM2; BRISC and BRCA1-A complex member 2 isoform X2 K12173 BRE; BRCA1-A complex subunit BRE
B UBL-specific proteases (ULPs)
C 477629 SENP1; sentrin-specific protease 1 isoform X3 K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C 478661 SENP2; sentrin-specific protease 2 isoform X4 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
C 607655 SENP3; sentrin-specific protease 3 K08593 SENP3; sentrin-specific protease 3 [EC:3.4.22.68]
C 488033 SENP5; sentrin-specific protease 5 isoform X2 K08594 SENP5; sentrin-specific protease 5 [EC:3.4.22.68]
C 481883 SENP6; sentrin-specific protease 6 isoform X1 K08595 SENP6; sentrin-specific protease 6 [EC:3.4.22.68]
C 487955 SENP7; sentrin-specific protease 7 K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C 487631 SENP8; sentrin-specific protease 8 K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C 476947 UCHL3; ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X1 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C 609713 DESI1; desumoylating isopeptidase 1 isoform X1 K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C 486019 USPL1; SUMO-specific isopeptidase USPL1 isoform X1 K23008 USPL1; SUMO-specific isopeptidase USPL1 [EC:3.4.22.-]
C COP9 signalosome (CSN) complex
D 483377 GPS1; COP9 signalosome complex subunit 1 isoform X1 K12175 GPS1; COP9 signalosome complex subunit 1
D 478295 COPS2; COP9 signalosome complex subunit 2 isoform X1 K12176 COPS2; COP9 signalosome complex subunit 2
D 479528 COPS3; COP9 signalosome complex subunit 3 isoform X2 K12177 COPS3; COP9 signalosome complex subunit 3
D 100856586 COPS4; COP9 signalosome complex subunit 4 isoform X1 K12178 COPS4; COP9 signalosome complex subunit 4
D 477901 COPS5; COP9 signalosome complex subunit 5 isoform X1 K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D 486722 COPS7A; COP9 signalosome complex subunit 7a isoform X2 K12180 COPS7; COP9 signalosome complex subunit 7
D 610156 COPS7B; COP9 signalosome complex subunit 7b K12180 COPS7; COP9 signalosome complex subunit 7
D 477417 COPS8; COP9 signalosome complex subunit 8 K12181 COPS8; COP9 signalosome complex subunit 8
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 1, 2024