+D Protein KO
#
Membrane Trafficking - Cryptosporidium hominis
%
!
AExocytosis
B Calcium ion-dependent exocytosis
C Synaptotagmins
C Septins
C DOC-2 proteins
C Acrosomal exocytosis proteins
C Phospholipases
D Chro.40288 phospholipase C, delta K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
C Kinases and associated proteins
D Chro.80381 phosphatidylinositol-4-phosphate 5-kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D Chro.70160 serine/threonine protein kinase; possibly sporulation specific K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D Chro.50237 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D Chro.40219 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
C Others
B Small GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D Chro.50460 calmodulin K02183 CALM; calmodulin
D Chro.20092 calmodulin K02183 CALM; calmodulin
D Chro.20184 calmodulin K02183 CALM; calmodulin
D Chro.80127 syntaxin binding protein K15292 STXBP1; syntaxin-binding protein 1
D Chro.60257 GTPase activator protein K19953 GRTP1; TBC1 domain family member 6
D Chro.70590 Rab geranylgeranyltransferase, alpha subunit isoform a K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D Chro.60212 prenyltransferase subunit K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D Chro.30275 type ii proteins geranylgeranyltransferase beta subunit K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
C Rho GTPases
C Other small GTPases and associated proteins
B Tethering complex
C Exocyst complex
C Exocyst complex assembly proteins
B Others
C Exomer complex
C Others
#
ASNARE
B Syntaxin (Qa)
C Stx-PM
D Chro.20126 syntaxin K08486 STX1B_2_3; syntaxin 1B/2/3
C Stx-Endo
C Stx-TGN / EE
D Chro.50300 hypothetical protein K08489 STX16; syntaxin 16
C Stx-cisGolgi
D Chro.10317 syntaxin 5 K08490 STX5; syntaxin 5
C Stx-sER
C Stx-rER
B SNAP-25[N] (Qb)
C Vti1
D Chro.30027 hypothetical protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
C NPSN
D Chro.30485 hypothetical protein K08494 NSPN; novel plant SNARE
C Gos1 (Gos28)
C Bos1 / Membrin
D Chro.10325 Golgi SNARE protein K08496 GOSR2; golgi SNAP receptor complex member 2
C Sec20
B SNAP-25[C] (Qc)
C STX6
C STX8
C STX10
C Bet1
D Chro.40178 hypothetical protein K08504 BET1; blocked early in transport 1
C Sft1
C Syp7
C Use1
B SNAP-25 (Qb,c)
C SNAP-23
C SNAP-25
D Chro.50201 hypothetical protein K18211 SNAP25; synaptosomal-associated protein 25
C SNAP-29
C SNAP-47
B VAMP, Ykt6, Sec22 (R)
C VAMP
D Chro.60028 synaptobrevin-like protein K08564 NYV1; vacuolar v-SNARE NYV1
C Ykt6
D Chro.60069 hypothetical protein K08516 YKT6; synaptobrevin homolog YKT6
C Sec22
D Chro.10215 hypothetical protein K08517 SEC22; vesicle transport protein SEC22
D Chro.10214 vesicle transport protein K08517 SEC22; vesicle transport protein SEC22
C Tomosyn
C Putative SNAREs
B SNARE associated proteins
C Syntaxin-binding proteins
D Chro.80127 syntaxin binding protein K15292 STXBP1; syntaxin-binding protein 1
D Chro.50483 Sec1 family K19998 SCFD1; sec1 family domain-containing protein 1
C Palmitoyltransferases
D Chro.60520 DHHC zinc finger multi-pass transmembrane protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D Chro.10160 cell cycle regulator with zn-finger domain K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D Chro.80577 hypothetical protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D Chro.20236 DHHC1 protein; Golgi apparatus-specific protein with DHHC zinc finger domain K20029 ZDHHC3_7_25; palmitoyltransferase ZDHHC3/7/25 [EC:2.3.1.225]
D Chro.50258 DHHC-type zinc finger domain-containing protein K20029 ZDHHC3_7_25; palmitoyltransferase ZDHHC3/7/25 [EC:2.3.1.225]
D Chro.10101 binding protein K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]
C Others
D Chro.20314 N-ethylmaleimide-sensitive factor; NSF; Sec18p K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D Chro.20087 SNAP protein (soluble N-ethylmaleimide-sensitive factor Attachment Protein) K15296 NAPA; alpha-soluble NSF attachment protein
D Chro.10043 cell division cycle protein 48 K13525 VCP; transitional endoplasmic reticulum ATPase
#
AEndocytosis
B Clathrin-mediated endocytosis
C Clathrin
D Chro.80150 clathrin, heavy polypeptide (Hc) K04646 CLTC; clathrin heavy chain
C Dynamin
D Chro.20357 dynamin-related protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C AP-2 complex
D Chro.60242 adapter-related protein complex 2 alpha 1 subunit K11824 AP2A; AP-2 complex subunit alpha
C Other core components
D Chro.20010 heat shock protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Low-density lipoprotein receptor (LDLR) family proteins
C LDLR adaptor proteins
D Chro.80381 phosphatidylinositol-4-phosphate 5-kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
C GPCR adaptor proteins
C Receptor tyrosine kinase (RTK) adaptor proteins
C Inositol 5-phosphatases
C Kinases
C Ubiquitin E3 ligases
C Others
B Lipid raft mediated endocytosis
C Caveolin-mediated endocytosis
D Chro.20357 dynamin-related protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C Flotillin-dependent endocytosis
C GRAF1-dependent endocytosis
D Chro.30115 ADP ribosylation factor 1 K07937 ARF1_2; ADP-ribosylation factor 1/2
D Chro.20360 hypothetical protein K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf6-dependent endocytosis
C RhoA-dependent endocytosis
D Chro.20357 dynamin-related protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
B Phagocytosis
C Fc receptors
C Integrins (complement receptors)
C Opsonins
C Toll-like receptors
C C-lectin receptors
C Scavenger receptors
C Coronins
C Others
D Chro.70423 unconventional myosin-A K10356 MYO1; myosin I
B Macropinocytosis
C Ras GTPases
C Kinases
D Chro.60213 phosphatidylinositol 3-kinase, root isoform K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
C Phospholipase C
D Chro.40288 phospholipase C, delta K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
C Sorting nexins
D Chro.40240 hypothetical protein K17917 SNX1_2; sorting nexin-1/2
C Others
B Bin/Amphiphysin/Rvs (BAR) family proteins
C N-BAR proteins
C F-BAR proteins
C I-BAR proteins
B Rab GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D Chro.80217 hypothetical protein K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D Chro.60213 phosphatidylinositol 3-kinase, root isoform K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D Chro.40233 hypothetical protein K20027 ZDHHC1_11; palmitoyltransferase ZDHHC1/11 [EC:2.3.1.225]
B Arf GTPases and associated proteins
C Arf GTPases
D Chro.30115 ADP ribosylation factor 1 K07937 ARF1_2; ADP-ribosylation factor 1/2
D Chro.20360 hypothetical protein K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf associated proteins
D Chro.20191 homeobox-containing protein K12486 SMAP; stromal membrane-associated protein
D Chro.80218 MGC69076 protein K23538 ELMOD; ELMO domain-containing protein
D Chro.70371 hypothetical protein K23538 ELMOD; ELMO domain-containing protein
B Others
C Fucosyltransferase
C EFR3-PI4KIII alpha complex and associated proteins
D Chro.60392 PI3_PI4_kinase K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
C Insulin-like growth factor-binding proteins
C Others
#
AEndosome - Lysosome transport
B Rab GTPases and associated proteins
C Rab GTPases
D Chro.70198 ras family GTPase K07897 RAB7A; Ras-related protein Rab-7A
C Retromer subcomplex
D Chro.40270 vacuolar sorting protein 35 K18468 VPS35; vacuolar protein sorting-associated protein 35
D Chro.70237 vacuolar protein sorting 29 K18467 VPS29; vacuolar protein sorting-associated protein 29
D Chro.20171 vps26 protein K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
C FTS/Hook/FHIP (FHF) complex
D Chro.40492 hypothetical protein K16536 HOOK3; protein HOOK3
C Rab associated proteins
D Chro.60213 phosphatidylinositol 3-kinase, root isoform K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D Chro.20158 proteasome subunit alpha type 7 (Proteasome component DD5) K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D Chro.30340 hypothetical protein K18469 TBC1D5; TBC1 domain family member 5
D Chro.40290 RIKEN cDNA C130070J12 gene K20174 OSBPL1_2; oxysterol-binding protein-related protein 1/2
D Chro.70590 Rab geranylgeranyltransferase, alpha subunit isoform a K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D Chro.60212 prenyltransferase subunit K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D Chro.30275 type ii proteins geranylgeranyltransferase beta subunit K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
B Arf GTPases and associated proteins
C Arf GTPases
C BLOC-one-related complex (BORC)
C N-acetyl transferase complex C (NatC)
C Other Arf associated proteins
B Endosomal sorting complexes required for transport (ESCRT)
C ESCRT-0 complex
C ESCRT-I complex
C ESCRT-II complex
C ESCRT-III complex
D Chro.70504 RIKEN cDNA 1500016L11 K12191 CHMP2A; charged multivesicular body protein 2A
D Chro.50474 hypothetical protein K12194 CHMP4A_B; charged multivesicular body protein 4A/B
D Chro.10381 AAA-family ATPase K12196 VPS4; vacuolar protein-sorting-associated protein 4
C ESCRT associated proteins
B Tethering complex
C CORVET complex
D Chro.40458 vacuolar protein sorting 11 K20179 VPS11; vacuolar protein sorting-associated protein 11
D Chro.70606 hypothetical protein K20180 VPS16; vacuolar protein sorting-associated protein 16
D Chro.80110 hypothetical protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D Chro.60276 Sec1-family protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
C Hops complex
D Chro.40458 vacuolar protein sorting 11 K20179 VPS11; vacuolar protein sorting-associated protein 11
D Chro.70606 hypothetical protein K20180 VPS16; vacuolar protein sorting-associated protein 16
D Chro.80110 hypothetical protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D Chro.60276 Sec1-family protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
D Chro.30136 hypothetical protein K20183 VPS39; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
B Acidification regulators
C Rabconnectin-3 complex
C RAVE complex
B Others
C AP-3 complex
C BLOC-1 complex
C BLOC-1 complex (yeast)
C BLOC-2 complex
C BLOC-3 complex
C Ferlins
C Others
D Chro.40269 CG11926 gene product K20195 MON1; vacuolar fusion protein MON1
#
AProtein recycling
B Rab GTPases and associated proteins
C Rab GTPases
C Rab4 associated proteins
C Rab11 associated proteins
D Chro.70601 RIKEN cDNA 2610034K17 K20241 WDR44; WD repeat-containing protein 44
D Chro.80472 hypothetical protein K14004 SEC13; protein transport protein SEC13
D Chro.40223 hypothetical protein K20242 EVI5; ecotropic viral integration site 5 protein
C Other Rab GTPase associated proteins
D Chro.80217 hypothetical protein K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D Chro.50352 Rad51 K04482 RAD51; DNA repair protein RAD51
B Others
C Glutamate receptor-interacting proteins (GRIPs)
C GRIP associated proteins
C EARP complex
D Chro.40334 Vps52 / Sac2 family protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D Chro.40389 ENSANGP00000011444 K20299 VPS53; vacuolar protein sorting-associated protein 53
C WASH complex
C Retriever complex
D Chro.70237 vacuolar protein sorting 29 K18467 VPS29; vacuolar protein sorting-associated protein 29
C Others
#
AEndosome - Golgi transport
B Rab GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D Chro.30060 vacuolar protein sorting-associated protein K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
D Chro.00004 hypothetical protein K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
B Arf GTPases and associated proteins
C Arf GTPases
D Chro.30115 ADP ribosylation factor 1 K07937 ARF1_2; ADP-ribosylation factor 1/2
D Chro.20360 hypothetical protein K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf GTPase associated proteins
D Chro.20341 beta 7 subunit of 20S proteasome K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1
D Chro.50282 hypothetical protein K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
D Chro.20191 homeobox-containing protein K12486 SMAP; stromal membrane-associated protein
D Chro.60364 cytohesin-like protein K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein
B Tethering complex
C Conserved oligomeric Golgi (COG) complex
D Chro.70418 A_IG002N01.1 gene product K20291 COG4; conserved oligomeric Golgi complex subunit 4
C GARP complex
D Chro.40334 Vps52 / Sac2 family protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D Chro.40389 ENSANGP00000011444 K20299 VPS53; vacuolar protein sorting-associated protein 53
C TRAPP complex II
D Chro.20401 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D Chro.70212 transport protein K20302 TRAPPC3; trafficking protein particle complex subunit 3
D Chro.60428 41-2 protein antigen precursor K20280 TRAPPC5; trafficking protein particle complex subunit 5
D Chro.30308 hypothetical protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
D Chro.80422 hypothetical protein K20310 TRAPPC13; trafficking protein particle complex subunit 13
B Others
C AP-1 complex
D Chro.50468 adaptor-related protein complex 1; gamma2-adaptin; clathrin-associated/assembly/adaptor protein, large, gamma-2 K12391 AP1G1; AP-1 complex subunit gamma-1
D Chro.40489 adapter-related protein complex 1 beta 1 subunit (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain) K12392 AP1B1; AP-1 complex subunit beta-1
D Chro.70304 clathrin-adaptor medium chain K12393 AP1M; AP-1 complex subunit mu
D Chro.80465 clathrin assembly protein AP19 K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
C AP-3 complex
C AP-4 complex
D Chro.80114 clathrin coat assembly like protein K12402 AP4M1; AP-4 complex subunit mu-1
C GGA
C Aftiphilin/p200/gamma-synergin complex
C Others
D Chro.60392 PI3_PI4_kinase K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D Chro.80381 phosphatidylinositol-4-phosphate 5-kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D Chro.40056 CG4196-PC K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D Chro.20253 hypothetical protein K26680 DOP1; protein dopey
#
AEndoplasmic reticulum (ER) - Golgi transport
B Forward pathways
C Coat protein complex II (COP-II)
D Chro.70265 small GTP-binding protein sar1 K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D Chro.80472 hypothetical protein K14004 SEC13; protein transport protein SEC13
D Chro.40040 hypothetical protein K14005 SEC31; protein transport protein SEC31
D Chro.30216 transport protein K14006 SEC23; protein transport protein SEC23
D Chro.80148 SEC24 K14007 SEC24; protein transport protein SEC24
D Chro.80513 hypothetical protein K14007 SEC24; protein transport protein SEC24
C TRAPP complex I
D Chro.20401 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D Chro.70212 transport protein K20302 TRAPPC3; trafficking protein particle complex subunit 3
D Chro.60428 41-2 protein antigen precursor K20280 TRAPPC5; trafficking protein particle complex subunit 5
D Chro.30308 hypothetical protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
C p24 family proteins
D Chro.70216 CG9308-PA K20347 TMED2; p24 family protein beta-1
D Chro.80586 hypothetical protein K20347 TMED2; p24 family protein beta-1
C PDI family proteins
D Chro.60023 protein disulphide isomerase K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D Chro.10099 hypothetical protein K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D Chro.70569 protein disulfide isomerase precursor (PDI) K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D Chro.60110 transmembrane, thioredoxin domain protein K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D Chro.70453 protein disulfide isomerase-related protein (provisional) K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C Rab GTPases
D Chro.60374 small GTP binding protein rab1a K07874 RAB1A; Ras-related protein Rab-1A
C Rab associated proteins
D Chro.80192 CG1418-PA K20359 RABAC1; PRA1 family protein 1
D Chro.30295 TBC domain K20360 TBC1D22; TBC1 domain family member 2
D Chro.50320 Golgi coiled coil protein GCC185 K20362 YIF1; protein transport protein YIF1
C ER-Golgi intermediate compartment (ERGIC) proteins
D Chro.70352 serologically defined breast cancer antigen 84 K20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3
D Chro.80337 serologically defined breast cancer antigen 84 like (42.9 kD) (XQ234) K20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3
D Chro.70049 heat shock protein 70 precursor K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
B Retrieval pathways
C Coat protein complex I (COP-I)
D Chro.80105 coatomer protein complex subunit alpha K05236 COPA; coatomer subunit alpha
D Chro.60040 hypothetical protein K17301 COPB1; coatomer subunit beta
D Chro.70561 coatomer beta' subunit K17302 COPB2; coatomer subunit beta'
D Chro.70219 coatomer gamma subunit K17267 COPG; coatomer subunit gamma
D Chro.70331 delta-COP K20471 COPD; coatomer subunit delta
D Chro.70463 CG3948-PA K20472 COPZ; coatomer subunit zeta
C NRZ (DSL1) complex
D Chro.10309 centromere protein ZW10 K11578 ZW10; protein transport protein DSL1/ZW10
C Golgi to ER traffic proteins (GET)
D Chro.70452 arsenical pump-driving ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D Chro.60112 hypothetical protein K23387 GET4; golgi to ER traffic protein 4
C Rab GTPases
C Rab associated proteins
D Chro.80131 endoplasmic reticulum retention receptor K10949 KDELR; ER lumen protein retaining receptor
D Chro.30295 TBC domain K20360 TBC1D22; TBC1 domain family member 2
B Others
C Oxysterol-binding proteins
D Chro.40290 RIKEN cDNA C130070J12 gene K20174 OSBPL1_2; oxysterol-binding protein-related protein 1/2
D Chro.10042 oxysterol-binding protein 3 K20463 OSBPL3_6_7; oxysterol-binding protein-related protein 3/6/7
C FXYD proteins
C YIPF proteins
D Chro.50129 hypothetical protein K22940 YIPF1_2; protein YIPF1/2
D Chro.40099 CG12404-PA K20363 YIPF5_7; protein YIPF5/7
D Chro.50227 terbinafine resistance locus protein YIP1 K22943 YIPF6; protein YIPF6
C ER membrane protein complex
D Chro.20233 hypothetical protein K23562 EMC1; ER membrane protein complex subunit 1
D Chro.40479 hypothetical protein K23563 EMC2; ER membrane protein complex subunit 2
D Chro.80325 hypothetical protein K23564 EMC3; ER membrane protein complex subunit 3
D Chro.60137 multi-pass transmembrane protein K23565 EMC4; ER membrane protein complex subunit 4
D Chro.70366 hypothetical protein K23569 EMC8_9; ER membrane protein complex subunit 8/9
C SEC61 complex
D Chro.70118 Pfsec61 K10956 SEC61A; protein transport protein SEC61 subunit alpha
C TRAP complex
C Multi-pass translocon (MPT) complex
D Chro.60186 dbj|baa86974.1 K21891 TMCO1; calcium load-activated calcium channel
C Post-GPI attachment to proteins factors (PGAP)
C Others
D Chro.50483 Sec1 family K19998 SCFD1; sec1 family domain-containing protein 1
D Chro.30358 hypothetical protein K20724 TMEM33; transmembrane protein 33
D Chro.80282 hypothetical protein K22698 SEY1; protein SEY1 [EC:3.6.5.-]
#
AAutophagy
B Autophagosome formation proteins
C ULK complex
C Atg1 complex
C PI3K complex
D Chro.60213 phosphatidylinositol 3-kinase, root isoform K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D Chro.60035 beclin1-like protein K08334 BECN; beclin
C ATG9 transmembrane protein
C Atg18-Atg2 complex
C Atg12 conjugation proteins
D Chro.40017 hypothetical protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
C Atg8 conjugation proteins
D Chro.70444 autophagy 8i K08341 GABARAP; GABA(A) receptor-associated protein
D Chro.40017 hypothetical protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D Chro.80308 autophagocytosis protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
B Cytoplasm to vacuolar targeting (CVT) pathway
C Selective cargos
D Chro.30408 hypothetical protein K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
C Cargo receptors
C Scaffold protein
C Other Cvt associated proteins
B Mitophagy
C Cargo receptors
C Scaffold proteins
C PINK1-Parkin associated proteins
D Chro.70140 ENSANGP00000022085 K19513 CLEC16A; protein CLEC16A
C Other mitophagy associated proteins
D Chro.60435 hexokinase i K00844 HK; hexokinase [EC:2.7.1.1]
B Pexophagy
C Selective cargos
C Cargo receptors
C Other pexophagy associated proteins
B Aggrephagy
C Cargo receptors
C Scaffold proteins
C Other aggrephagy associated proteins
D Chro.10043 cell division cycle protein 48 K13525 VCP; transitional endoplasmic reticulum ATPase
B Xenophagy
C Cargo receptors
C Other xenophagy associated proteins
B Chaperone mediated autophagy (CMA)
C Selective cargos
D Chro.10335 fructose-1,6-bisphosphate aldolase K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D Chro.60434 glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D Chro.70471 phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D Chro.10234 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D Chro.40266 required with RAD23 for duplication of the spindle pole body; Dsk2p K04523 UBQLN; ubiquilin
D Chro.70562 suppressor of NosA K04523 UBQLN; ubiquilin
C Cargo receptors
C Chaperones
D Chro.20010 heat shock protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D Chro.30427 heat shock protein 83 K04079 HSP90A; molecular chaperone HtpG
C Co-chaperones
C Other CMA associated proteins
D Chro.60459 elongation factor 1-alpha (EF-1-ALPHA) K03231 EEF1A; elongation factor 1-alpha
B Other autophagy associated proteins
C RNautophagy/DNautophagy
C Micronucleophagy
C Midbophagy
C Glycophagy
C TRIM-directed selective autophagy
C ER-mitochondria tethering complex
D Chro.60303 conserverd MSP-domain transmembrane protein K10707 VAPB; vesicle-associated membrane protein-associated protein B
C mTORC1 complex
C mTORC2 complex
C SEACIT/GATOR1 complex
D Chro.20167 CG9104-PA K20405 NPRL2; nitrogen permease regulator 2
C SEACAT/GATOR2 complex
D Chro.10336 MGC47001 K20408 WDR24; SEA/GATOR complex protein SEA2/WDR24
D Chro.80472 hypothetical protein K14004 SEC13; protein transport protein SEC13
C KICSTOR complex
C Rab GTPases
D Chro.60374 small GTP binding protein rab1a K07874 RAB1A; Ras-related protein Rab-1A
C Rab associated proteins
C Others
D Chro.60086 OSK4 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D Chro.60584 protein kinase K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D Chro.70100 hypothetical protein K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D Chro.50440 hypothetical protein K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D Chro.40163 hypothetical protein K17606 IGBP1; immunoglobulin-binding protein 1
D Chro.70533 hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D Chro.30489 hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D Chro.40505 hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
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AOthers
B NADPH oxidases (Nox) and associated proteins
C NADPH oxidases
C Nox associated proteins
B Actin-binding proteins
C Myosins
D Chro.70423 unconventional myosin-A K10356 MYO1; myosin I
D Chro.70483 myosin B K10357 MYO5; myosin V
D Chro.60497 myosin-related protein K10357 MYO5; myosin V
C Arp2/3 complex
D Chro.30367 actin-related complex protein K05755 ARPC4; actin related protein 2/3 complex, subunit 4
D Chro.50334 hypothetical protein K17260 ACTR2; actin-related protein 2
D Chro.10273 hypothetical protein K18584 ACTR3; actin-related protein 3
C Nucleation-promoting factors (NPFs)
D Chro.60450 hydroxyproline-rich glycoprotein dz-hrgp precursor K23612 WASL; neural Wiskott-Aldrich syndrome protein
C Others
D Chro.50095 actin depolymerizing factor-related K05765 CFL; cofilin
D Chro.50350 LD24380p K17261 CAP1_2; adenylyl cyclase-associated protein
B Mucins
C Membrane bound mucins
C Secretory mucins
B Rab GTPases of specific organelles
C Melanosome
C Auto phagosome
C Lipid droplets
C Mitochondrion
B Rho GTPase associated proteins
C Rho GTPase-activating proteins
D Chro.40339 rhoGAP protein K18470 ARHGAP1; Rho GTPase-activating protein 1
C Rho guanine nucleotide exchange factors (GEFs)
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 10, 2024