+C Two-component system KO
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Two-Component System - Desulfitobacterium hafniense DCB-2
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C Dhaf_4049 PAS/PAC sensor signal transduction histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C Dhaf_2159 two component transcriptional regulator, winged helix family K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
C Dhaf_4050 two component transcriptional regulator, winged helix family K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
C Dhaf_1237 two component transcriptional regulator, winged helix family K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
B SenX3-RegX3 (phosphate starvation response)
C Dhaf_2147 histidine kinase K07768 senX3; two-component system, OmpR family, sensor histidine kinase SenX3 [EC:2.7.13.3]
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
B RstB-RstA
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
C Dhaf_4625 histidine kinase K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C Dhaf_1586 histidine kinase K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C Dhaf_1164 UspA domain protein K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C Dhaf_1587 two component transcriptional regulator, winged helix family K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
C Dhaf_4626 two component transcriptional regulator, winged helix family K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
C Dhaf_3738 histidine kinase K07651 resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3]
C Dhaf_3739 two component transcriptional regulator, winged helix family K07775 resD; two-component system, OmpR family, response regulator ResD
C Dhaf_1367 two component transcriptional regulator, winged helix family K07775 resD; two-component system, OmpR family, response regulator ResD
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
C Dhaf_0522 histidine kinase K19081 braS; two-component system, OmpR family, sensor histidine kinase BraS/BceS [EC:2.7.13.3]
C Dhaf_0521 two component transcriptional regulator, winged helix family K19082 braR; two-component system, OmpR family, response regulator protein BraR/BceR
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
C Dhaf_1841 histidine kinase K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
C Dhaf_2158 histidine kinase K18345 vanSB; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
B VanS-VanR (VanE type vancomycin resistance)
C Dhaf_1666 histidine kinase K18350 vanSC; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
C Dhaf_1665 two component transcriptional regulator, winged helix family K18349 vanRC; two-component system, OmpR family, response regulator VanR
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
C Dhaf_2230 histidine kinase K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]
C Dhaf_2231 two component transcriptional regulator, winged helix family K18941 arlR; two-component system, OmpR family, response regulator ArlR
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C Dhaf_1006 histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C Dhaf_1005 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator
C Dhaf_1866 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator
C Dhaf_0041 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator
C Dhaf_0940 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
C Dhaf_4693 histidine kinase K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
C Dhaf_1284 histidine kinase K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
C Dhaf_0286 histidine kinase K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
B ComP-ComA (competence)
C Dhaf_0099 histidine kinase K07680 comP; two-component system, NarL family, sensor histidine kinase ComP [EC:2.7.13.3]
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
C Dhaf_2790 Sensor DegS domain protein K07777 degS; two-component system, NarL family, sensor histidine kinase DegS [EC:2.7.13.3]
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
C Dhaf_1194 two component transcriptional regulator, LuxR family K07696 nreC; two-component system, NarL family, response regulator NreC
C Dhaf_1230 two component transcriptional regulator, LuxR family K07696 nreC; two-component system, NarL family, response regulator NreC
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
C Dhaf_3229 histidine kinase K13533 kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]
C Dhaf_1253 signal transduction histidine kinase, nitrogen specific, NtrB K13533 kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]
C Dhaf_0916 signal transduction histidine kinase, nitrogen specific, NtrB K13533 kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]
C Dhaf_4841 response regulator receiver protein K02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F
C Dhaf_3481 sporulation transcriptional activator Spo0A K07699 spo0A; two-component system, response regulator, stage 0 sporulation protein A
C Dhaf_3021 sporulation transcriptional activator Spo0A K07699 spo0A; two-component system, response regulator, stage 0 sporulation protein A
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
C Dhaf_4645 signal transduction histidine kinase regulating citrate/malate metabolism K11691 K11691; two-component system, CitB family, sensor histidine kinase DctS [EC:2.7.13.3]
C Dhaf_4644 response regulator receiver and unknown domain protein K11692 K11692; two-component system, CitB family, response regulator DctR
C Dhaf_1239 response regulator receiver and unknown domain protein K11692 K11692; two-component system, CitB family, response regulator DctR
B MalK-MalR (malate transport)
C Dhaf_4311 signal transduction histidine kinase regulating citrate/malate metabolism K11614 yufL; two-component system, CitB family, sensor histidine kinase MalK [EC:2.7.13.3]
C Dhaf_4310 response regulator receiver and unknown domain protein K11615 malR; two-component system, CitB family, response regulator MalR
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
C Dhaf_1339 signal transduction histidine kinase, LytS K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
C Dhaf_2452 signal transduction histidine kinase, LytS K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
C Dhaf_4305 signal transduction histidine kinase, LytS K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
C Dhaf_0494 signal transduction histidine kinase, LytS K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
C Dhaf_3686 two component transcriptional regulator, LytTR family K02477 K02477; two-component system, LytTR family, response regulator
C Dhaf_4408 two component transcriptional regulator, LytTR family K02477 K02477; two-component system, LytTR family, response regulator
C Dhaf_1568 response regulator receiver and SARP domain protein K02477 K02477; two-component system, LytTR family, response regulator
C Dhaf_1614 response regulator receiver and SARP domain protein K02477 K02477; two-component system, LytTR family, response regulator
C Dhaf_0495 response regulator receiver and SARP domain protein K02477 K02477; two-component system, LytTR family, response regulator
C Dhaf_0497 response regulator receiver and SARP domain protein K02477 K02477; two-component system, LytTR family, response regulator
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
C Dhaf_3047 sigma54 specific transcriptional regulator, Fis family K07713 zraR; two-component system, NtrC family, response regulator HydG
C Dhaf_0198 two component, sigma54 specific, transcriptional regulator, Fis family K07713 zraR; two-component system, NtrC family, response regulator HydG
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
C Dhaf_4673 PAS/PAC sensor signal transduction histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C Dhaf_0197 histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
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ACheA family
B CheA-CheYBV (chemotaxis)
C Dhaf_4155 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C Dhaf_4540 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C Dhaf_4140 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C Dhaf_4153 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
C Dhaf_4590 putative sensor with HAMP domain K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C Dhaf_3979 two component transcriptional regulator, AraC family K07720 yesN; two-component system, response regulator YesN
C Dhaf_4320 transcriptional regulator, AraC family K07720 yesN; two-component system, response regulator YesN
C Dhaf_4591 two component transcriptional regulator, AraC family K07720 yesN; two-component system, response regulator YesN
B CikA
B RegB-RegA (redox response)
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C Dhaf_4541 multi-sensor hybrid histidine kinase K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3]
B PdtaS-PdtaR
C Dhaf_0995 response regulator receiver and ANTAR domain protein K22010 pdtaR; two-component system, response regulator PdtaR
B NasS-NasT
B Unclassified
C Dhaf_1567 signal transduction histidine kinase, LytS K19694 chiS; two-component system, sensor histidine kinase ChiS
C Dhaf_0411 signal transduction histidine kinase, LytS K19694 chiS; two-component system, sensor histidine kinase ChiS
C Dhaf_0493 signal transduction histidine kinase, LytS K19694 chiS; two-component system, sensor histidine kinase ChiS
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023