+F Repair protein KO
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DNA Repair and Recombination Proteins - Lactobacillus gasseri ATCC 33323
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D LGAS_0090 Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D LGAS_0245 Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D LGAS_0988 Acetyltransferase, GNAT family K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E LGAS_1297 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LGAS_0087 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E LGAS_1026 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D LGAS_0862 NUDIX family hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LGAS_1457 NUDIX family hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LGAS_0335 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D LGAS_0090 Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D LGAS_0245 Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D LGAS_0988 Acetyltransferase, GNAT family K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E LGAS_1297 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LGAS_0792 Uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E LGAS_0087 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E LGAS_0477 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E LGAS_1420 Formamidopyrimidine-DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E LGAS_1026 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E LGAS_1689 Exonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E LGAS_0034 Exonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E LGAS_0826 exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E LGAS_1515 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E LGAS_1421 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E LGAS_1317 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E LGAS_1665 Excinuclease ATPase subunit K03701 uvrA; excinuclease ABC subunit A
E LGAS_1318 Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E LGAS_0871 Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E LGAS_1516 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LGAS_1680 Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LGAS_1421 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E LGAS_1515 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F LGAS_0284 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F LGAS_0285 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F LGAS_0316 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F LGAS_0225 DNA-directed RNA polymerase, delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
F LGAS_0759 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F LGAS_0271 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E LGAS_0412 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E LGAS_0426 Mismatch repair ATPase (MutS family) K07456 mutS2; DNA mismatch repair protein MutS2
E LGAS_1886 MutS family ATPase K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E LGAS_0413 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E LGAS_0752 Exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E LGAS_0753 Exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E LGAS_0880 DNA polymerase III catalytic subunit, DnaE type K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E LGAS_0809 DNA polymerase III catalytic subunit, PolC type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E LGAS_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E LGAS_1173 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E LGAS_0374 DNA replication ATPase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E LGAS_1647 DNA polymerase III, alpha subunit (gram-positive type) K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E LGAS_1294 DNA polymerase III, epsilon subunit related 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E LGAS_0368 DNA polymerase III, gamma/tau subunit K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E LGAS_1515 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E LGAS_1516 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LGAS_1680 Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LGAS_0008 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E LGAS_1186 ATP-dependent DNA helicase, RecD/TraA family K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E LGAS_1338 RecA protein K03553 recA; recombination protein RecA
E LGAS_0414 Holliday junction DNA helicase subunit RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E LGAS_0415 Holliday junction DNA helicase subunit RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E LGAS_0760 replication restart DNA helicase PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E LGAS_1338 RecA protein K03553 recA; recombination protein RecA
E LGAS_0336 DNA replication and repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E LGAS_0004 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E LGAS_0771 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E LGAS_0826 exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E LGAS_1117 DNA replication and repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E LGAS_0370 DNA replication and repair protein RecR K06187 recR; recombination protein RecR
E LGAS_0756 DNA replication and repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E LGAS_1024 Penicillin-binding protein-related factor A, putative recombinase K03700 recU; recombination protein U
E LGAS_0414 Holliday junction DNA helicase subunit RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E LGAS_0415 Holliday junction DNA helicase subunit RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E LGAS_1031 ATP-dependent exoDNAse (exonuclease V) beta subunit K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E LGAS_1032 ATP-dependent nuclease, subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F LGAS_0006 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F LGAS_0005 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F LGAS_0916 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F LGAS_0894 bacterial nucleoid protein Hbs K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F LGAS_0826 exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F LGAS_1117 DNA replication and repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F LGAS_0370 DNA replication and repair protein RecR K06187 recR; recombination protein RecR
F LGAS_1515 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F LGAS_1003 ATP-dependent DNA helicase, RecQ-like protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F LGAS_1317 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F LGAS_1665 Excinuclease ATPase subunit K03701 uvrA; excinuclease ABC subunit A
F LGAS_1318 Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D LGAS_0418 Nucleotidyltransferase/DNA polymerase for DNA repair K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D LGAS_1455 Nucleotidyltransferase/DNA polymerase for DNA repair K03502 umuC; DNA polymerase V
C Other SOS response factors
D LGAS_1338 RecA protein K03553 recA; recombination protein RecA
D LGAS_0793 Transcriptional regulator, xre family K01356 lexA; repressor LexA [EC:3.4.21.88]
D LGAS_0756 DNA replication and repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D LGAS_0008 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D LGAS_1370 hypothetical protein, RecX family K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D LGAS_1030 Rad3-related DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D LGAS_1556 Lhr-like helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D LGAS_0862 NUDIX family hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LGAS_1457 NUDIX family hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LGAS_0335 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D LGAS_1705 ribonucleoside-diphosphate reductase class Ib beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D LGAS_0419 Phosphoesterase, DHH family protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024