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Transfer RNA Biogenesis - Monodelphis domestica (gray short-tailed opossum)
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
D 100023145 POP1; POP1 homolog, ribonuclease P/MRP subunit K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D 100014928 POP4; POP4 homolog, ribonuclease P/MRP subunit K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D 100025975 POP5; POP5 homolog, ribonuclease P/MRP subunit K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D 100024616 RPP30; ribonuclease P/MRP subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D 103103048 RPP21; ribonuclease P/MRP subunit p21 K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
D 100014407 RPP14; ribonuclease P/MRP subunit p14 K14529 RPP14; ribonuclease P protein subunit RPP14 [EC:3.1.26.5]
D 100017327 POP7; POP7 homolog, ribonuclease P/MRP subunit K14527 RPP20; ribonuclease P/MRP protein subunit RPP20 [EC:3.1.26.5]
D 100028859 RPP25L; ribonuclease P/MRP subunit p25 like K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 100030098 RPP25; ribonuclease P/MRP subunit p25 K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 100027139 RPP38; ribonuclease P/MRP subunit p38 K14523 RPP38; ribonucleases P/MRP protein subunit RPP38 [EC:3.1.26.5]
D 100020802 RPP40; ribonuclease P/MRP subunit p40 K14530 RPP40; ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D 100010800 ELAC1; elaC ribonuclease Z 1 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 100021330 ELAC2; elaC ribonuclease Z 2 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 100032595 RNASET2; ribonuclease T2 K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
D 100016159 PTCD1; pentatricopeptide repeat domain 1 K17710 PTCD1; pentatricopeptide repeat domain-containing protein 1
C CCA adding factors
D 100022252 TRNT1; tRNA nucleotidyl transferase 1 K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
D 100015319 TSEN2; tRNA splicing endonuclease subunit 2 K15322 TSEN2; tRNA-splicing endonuclease subunit Sen2 [EC:4.6.1.16]
D 100028470 TSEN34; tRNA splicing endonuclease subunit 34 K15323 TSEN34; tRNA-splicing endonuclease subunit Sen34 [EC:4.6.1.16]
D 100024293 TSEN15; tRNA splicing endonuclease subunit 15 K15324 TSEN15; tRNA-splicing endonuclease subunit Sen15
D 100027330 TSEN54; tRNA splicing endonuclease subunit 54 K15326 TSEN54; tRNA-splicing endonuclease subunit Sen54
C tRNA splicing ligase complex
D 100016063 RTCB; RNA 2',3'-cyclic phosphate and 5'-OH ligase K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D 100014616 C7H2orf49; chromosome 7 open reading frame, human C2orf49 K15432 ASW; ashwin
D 100009757 C1H14orf166; chromosome 1 open reading frame, human C14orf166 K15433 CGI99; RLL motif containing protein 1
D 100027069 FAM98B; family with sequence similarity 98 member B K15434 FAM98B; protein FAM98B
D 100013419 DDX1; DEAD-box helicase 1 K13177 DDX1; ATP-dependent RNA helicase DDX1 [EC:5.6.2.7]
D 100025926 ZBTB8OS; zinc finger and BTB domain containing 8 opposite strand K24956 ZBTB8OS; protein archease
C Other tRNA splicing factors
D 100028474 TRPT1; tRNA phosphotransferase 1 K10669 TRPT1; 2'-phosphotransferase [EC:2.7.1.160]
B tRNA transport factors
C tRNA export factors
D 100020008 RAN; RAN, member RAS oncogene family K07936 RAN; GTP-binding nuclear protein Ran
D 103104577 XPOT; exportin for tRNA K14288 XPOT; exportin-T
D 100031924 XPO1; exportin 1 K14290 XPO1; exportin-1
D 100011817 XPO5; exportin 5 K14289 XPO5; exportin-5
D 100016447 EEF1A1; eukaryotic translation elongation factor 1 alpha 1 K03231 EEF1A; elongation factor 1-alpha
D 100011677 elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
D 100025136 EEF1A2; eukaryotic translation elongation factor 1 alpha 2 K03231 EEF1A; elongation factor 1-alpha
D 100017040 SCYL1; SCY1 like pseudokinase 1 K08876 SCYL1; SCY1-like protein 1
D 100010823 GTPBP1; GTP binding protein 1 K24887 GTPBP1; GTP-binding protein 1
C tRNA import factors
D 100015111 TNPO3; transportin 3 K15436 TRPO3; transportin-3
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D 100017727 EPRS; glutamyl-prolyl-tRNA synthetase K14163 EPRS; bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]
D 100617355 EARS2; glutamyl-tRNA synthetase 2, mitochondrial K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D 100032507 PARS2; prolyl-tRNA synthetase 2, mitochondrial (putative) K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D 100029867 IARS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 100024337 IARS2; isoleucyl-tRNA synthetase 2, mitochondrial K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 100028509 LARS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 100029820 LARS2; leucyl-tRNA synthetase 2, mitochondrial K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 100029705 MARS2; methionyl-tRNA synthetase 2, mitochondrial K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 100020835 QARS; glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D 100030898 arginine--tRNA ligase, cytoplasmic-like K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 100019290 RARS2; arginyl-tRNA synthetase 2, mitochondrial K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 100026083 arginine--tRNA ligase, cytoplasmic K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 100029118 KARS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D 100029003 lysine--tRNA ligase-like K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D 100016552 DARS; aspartyl-tRNA synthetase K22503 DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 100021040 DARS2; aspartyl-tRNA synthetase 2, mitochondrial K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 100617054 AIMP1; aminoacyl tRNA synthetase complex interacting multifunctional protein 1 K15437 AIMP1; aminoacyl tRNA synthase complex-interacting multifunctional protein 1
D 100020378 AIMP2; aminoacyl tRNA synthetase complex interacting multifunctional protein 2 K15438 AIMP2; aminoacyl tRNA synthase complex-interacting multifunctional protein 2
D 100027708 EEF1E1; eukaryotic translation elongation factor 1 epsilon 1 K15439 EEF1E1; eukaryotic translation elongation factor 1 epsilon-1
C Other AARSs
D 100011180 AARS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 100013354 AARS2; alanyl-tRNA synthetase 2, mitochondrial K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 100016329 NARS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 100027168 NARS2; asparaginyl-tRNA synthetase 2, mitochondrial (putative) K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 100021518 GARS; glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D 100021039 TARSL2; threonyl-tRNA synthetase like 2 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 100021284 TARS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 100017092 TARS2; threonyl-tRNA synthetase 2, mitochondrial (putative) K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 100029990 SARS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 100619616 SARS2; seryl-tRNA synthetase 2, mitochondrial K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 100015261 CARS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 100619335 CARS2; cysteinyl-tRNA synthetase 2, mitochondrial (putative) K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 100023525 VARS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D 100024455 VARS2; valyl-tRNA synthetase 2, mitochondrial K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D 100026449 HARS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 100026483 HARS2; histidyl-tRNA synthetase 2, mitochondrial K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 100027432 FARSA; phenylalanyl-tRNA synthetase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 100028212 FARS2; phenylalanyl-tRNA synthetase 2, mitochondrial K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 100015798 FARSB; phenylalanyl-tRNA synthetase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D 100026880 YARS2; tyrosyl-tRNA synthetase 2 K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 100025987 YARS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 100027731 tyrosine--tRNA ligase, mitochondrial-like K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 100018040 WARS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 100012545 WARS2; tryptophanyl tRNA synthetase 2, mitochondrial K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D 100031436 DTD1; D-tyrosyl-tRNA deacylase 1 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 100012824 DTD2; D-tyrosyl-tRNA deacylase 2 (putative) K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 100010440 AARSD1; alanyl-tRNA synthetase domain containing 1 K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
C AARS associated factors
D 100015063 TRNAU1AP; tRNA selenocysteine 1 associated protein 1 K25102 TRNAU1AP; tRNA selenocysteine 1-associated protein 1
D 100027674 HINT1; histidine triad nucleotide binding protein 1 K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D 100027996 HINT2; histidine triad nucleotide binding protein 2 K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D 100030733 HINT3; histidine triad nucleotide binding protein 3 K12150 HINT3; adenosine 5'-monophosphoramidase HINT3 [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
D 100021062 ADAT1; adenosine deaminase, tRNA specific 1 K15440 TAD1; tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
D 100031790 ADAT2; adenosine deaminase, tRNA specific 2 K15441 TAD2; tRNA-specific adenosine deaminase 2 [EC:3.5.4.-]
D 100018548 ADAT3; adenosine deaminase, tRNA specific 3 K15442 TAD3; tRNA-specific adenosine deaminase 3
C Dihydorouridine synthases
D 100029826 DUS1L; dihydrouridine synthase 1 like K05542 DUS1; tRNA-dihydrouridine synthase 1 [EC:1.3.1.88]
D 100021875 DUS2; dihydrouridine synthase 2 K05543 DUS2; tRNA-dihydrouridine synthase 2 [EC:1.3.1.91]
D 100025142 DUS3L; dihydrouridine synthase 3 like K05544 DUS3; tRNA-dihydrouridine synthase 3 [EC:1.3.1.89]
D 100010303 DUS4L; dihydrouridine synthase 4 like K05545 DUS4; tRNA-dihydrouridine synthase 4 [EC:1.3.1.90]
C Methylthiotransferase
D 100024680 CDKAL1; CDK5 regulatory subunit associated protein 1 like 1 K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
C Methyltransferases
D 100027314 TRMT1; tRNA methyltransferase 1 K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D 100026163 TRMT2A; tRNA methyltransferase 2 homolog A K15332 TRMT2A; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.-]
D 100020295 TRMT2B; tRNA (uracil(54)-C(5))-methyltransferase homolog K15331 TRMT2B; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D 100023388 tRNA (uracil(54)-C(5))-methyltransferase homolog K15331 TRMT2B; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D 100028786 TARBP1; TAR (HIV-1) RNA binding protein 1 K15333 TRM3; tRNA guanosine-2'-O-methyltransferase [EC:2.1.1.34]
D 100018054 NSUN2; NOP2/Sun RNA methyltransferase family member 2 K15335 NSUN2; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.203]
D 100618685 NSUN3; NOP2/Sun RNA methyltransferase family member 3 K21969 NSUN3; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.-]
D 100026717 NSUN6; NOP2/Sun RNA methyltransferase family member 6 K21971 NSUN6; methyltransferase NSUN6 [EC:2.1.1.-]
D 100027143 TRMT5; tRNA methyltransferase 5 K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D 100017030 TRMT61A; tRNA methyltransferase 61A K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D 100031313 TRMT61B; tRNA methyltransferase 61B K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D 100033292 TRMT6; tRNA methyltransferase 6 K03256 TRM6; tRNA (adenine58-N1)-methyltransferase non-catalytic subunit
D 100022441 FTSJ1; FtsJ RNA methyltransferase homolog 1 (E. coli) K14864 FTSJ1; tRNA (cytidine32/guanosine34-2'-O)-methyltransferase [EC:2.1.1.205]
D 100031502 METTL1; methyltransferase like 1 K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D 100025488 METTL2A; methyltransferase like 2A K24974 METTL2; tRNA N(3)-methylcytidine methyltransferase METTL2 [EC:2.1.1.-]
D 100030464 METTL6; methyltransferase like 6 K00599 METTL6; tRNA N(3)-methylcytidine methyltransferase METTL6 [EC:2.1.1.-]
D 100032528 ALKBH8; alkB homolog 8, tRNA methyltransferase K10770 ALKBH8; alkylated DNA repair protein alkB homolog 8 [EC:1.14.11.- 2.1.1.229]
D 100015691 TRMT10A; tRNA methyltransferase 10A K15445 TRMT10; tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221]
D 100018930 TRMT10B; tRNA methyltransferase 10B K15445 TRMT10; tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221]
D 100030752 TRMT11; tRNA methyltransferase 11 homolog K15430 TRM11; tRNA (guanine10-N2)-methyltransferase [EC:2.1.1.214]
D 100032957 TRMT13; tRNA methyltransferase 13 homolog K15446 TRM13; tRNA:m4X modification enzyme [EC:2.1.1.225]
D 100020106 TRMT44; tRNA methyltransferase 44 homolog (S. cerevisiae) K15447 TRM44; tRNASer (uridine44-2'-O)-methyltransferase [EC:2.1.1.211]
D 100024029 WDR4; WD repeat domain 4 K15443 TRM82; tRNA (guanine-N(7)-)-methyltransferase subunit TRM82
D 100026881 TRDMT1; tRNA aspartic acid methyltransferase 1 K15336 TRDMT1; tRNA (cytosine38-C5)-methyltransferase [EC:2.1.1.204]
D 100020108 TRMO; tRNA methyltransferase O K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D 100010958 TYW1; tRNA-yW synthesizing protein 1 homolog K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D 100020165 TRMT12; tRNA methyltransferase 12 homolog K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D 100023277 tRNA wybutosine-synthesizing protein 2 homolog K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D 100011614 TYW3; tRNA-yW synthesizing protein 3 homolog K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]
D 107650707 LCMT2; leucine carboxyl methyltransferase 2 K15451 PPM2; tRNA wybutosine-synthesizing protein 4 [EC:2.1.1.290 2.3.1.231]
D 100022563 TYW5; tRNA-yW synthesizing protein 5 K18066 TYW5; tRNA wybutosine-synthesizing protein 5 [EC:1.14.11.42]
D 100022774 BCDIN3D; BCDIN3 domain containing RNA methyltransferase K25191 BCDIN3D; RNA 5'-monophosphate methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D 100028468 PUS1; pseudouridylate synthase 1 K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D 100018995 PUS3; pseudouridylate synthase 3 K01855 PUS3; tRNA pseudouridine38/39 synthase [EC:5.4.99.45]
D 100027192 TRUB1; TruB pseudouridine synthase family member 1 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D 100018668 PUS7; pseudouridylate synthase 7 (putative) K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D 100031947 PUS10; pseudouridylate synthase 10 K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
D 100019302 RPUSD4; RNA pseudouridylate synthase domain containing 4 K22538 RPUSD4; mitochondrial RNA pseudouridine synthase RPUSD4 [EC:5.4.99.-]
C Thiolation factors
D 100028714 TRMU; tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase K21027 TRMU; tRNA-5-taurinomethyluridine 2-sulfurtransferase [EC:2.8.1.14]
D 100028227 CTU1; cytosolic thiouridylase subunit 1 K14168 CTU1; cytoplasmic tRNA 2-thiolation protein 1 [EC:2.7.7.-]
D 100026174 CTU2; cytosolic thiouridylase subunit 2 K14169 CTU2; cytoplasmic tRNA 2-thiolation protein 2
D 100032517 NFS1; NFS1, cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D 100011672 URM1; ubiquitin related modifier 1 K12161 URM1; ubiquitin related modifier 1
D 100022807 MOCS3; molybdenum cofactor synthesis 3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C KEOPS/EKC complex
D 100029708 TP53RK; TP53 regulating kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D 100021300 OSGEPL1; O-sialoglycoprotein endopeptidase like 1 K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D 100022836 OSGEP; O-sialoglycoprotein endopeptidase K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D 100012150 TPRKB; TP53RK binding protein K15901 TPRKB; EKC/KEOPS complex subunit TPRKB/CGI121
D 100020674 EKC/KEOPS complex subunit LAGE3-like K15902 LAGE3; EKC/KEOPS complex subunit LAGE3/PCC1
D 100016852 GON7; GON7, KEOPS complex subunit homolog K15903 GON7; EKC/KEOPS complex subunit GON7
C Elongator complex
D 100010616 IKBKAP; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein K11373 ELP1; elongator complex protein 1
D 100013397 ELP2; elongator acetyltransferase complex subunit 2 K11374 ELP2; elongator complex protein 2
D 100033182 ELP3; elongator acetyltransferase complex subunit 3 K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D 100030999 ELP4; elongator acetyltransferase complex subunit 4 K11375 ELP4; elongator complex protein 4
D 100011010 ELP5; elongator acetyltransferase complex subunit 5 K11376 ELP5; elongator complex protein 5
D 100018416 ELP6; elongator acetyltransferase complex subunit 6 K11377 ELP6; elongator complex protein 6
C Elongator related proteins
D 100024181 DPH3; diphthamide biosynthesis 3 K15455 DPH3; diphthamide biosynthesis protein 3
D 100018881 DPH3 homolog K15455 DPH3; diphthamide biosynthesis protein 3
D 100019237 KTI12; KTI12 chromatin associated homolog K15456 KTI12; protein KTI12
C Other tRNA modification factors
D 100031786 YRDC; yrdC N6-threonylcarbamoyltransferase domain containing K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D 100032056 TRIT1; tRNA isopentenyltransferase 1 K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D 100021331 MTO1; mitochondrial tRNA translation optimization 1 K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D 100011778 QTRT1; queuine tRNA-ribosyltransferase catalytic subunit 1 K00777 QTRT1; queuine tRNA-ribosyltransferase catalytic subunit [EC:2.4.2.64]
D 100014067 QTRT2; queuine tRNA-ribosyltransferase accessory subunit 2 K15407 QTRT2; queuine tRNA-ribosyltransferase accessory subunit
D 100011764 SEPHS1; selenophosphate synthetase 1 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 100024928 SEPHS2; selenophosphate synthetase 2 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 100026336 THUMPD1; THUMP domain containing 1 K06963 TAN1; tRNA acetyltransferase TAN1
D 100013856 THUMP domain-containing protein 1-like K06963 TAN1; tRNA acetyltransferase TAN1
D 100025355 THG1L; tRNA-histidine guanylyltransferase 1 like K10761 THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79]
D 100025687 ATE1; arginyltransferase 1 K00685 ATE1; arginyl-tRNA---protein transferase [EC:2.3.2.8]
D 100027384 DALRD3; DALR anticodon binding domain containing 3 K24973 DALRD3; DALR anticodon-binding domain-containing protein 3
B tRNA degradation factors
C TRAMP complex
D 100018235 PAPD7; poly(A) RNA polymerase D7, non-canonical K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
D 100617010 PAPD5; poly(A) RNA polymerase D5, non-canonical K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
D 100018358 ZCCHC7; zinc finger CCHC-type containing 7 K12597 AIR1_2; protein AIR1/2
D 100017078 SKIV2L2; Ski2 like RNA helicase 2 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
C Rapid tRNA decay (RTD) pathway factors
D 100013672 XRN1; 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
D 100031372 XRN2; 5'-3' exoribonuclease 2 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D 100017763 BPNT1; 3'(2'), 5'-bisphosphate nucleotidase 1 K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
D 100029629 ANG; angiogenin K16631 ANG; angiogenin [EC:3.1.27.-]
D 100024963 IFIT5; interferon-induced protein with tetratricopeptide repeats 5 K24850 IFIT5; interferon-induced protein with tetratricopeptide repeats 5
#
AProkaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D 100010800 ELAC1; elaC ribonuclease Z 1 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 100021330 ELAC2; elaC ribonuclease Z 2 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 100032595 RNASET2; ribonuclease T2 K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
C CCA adding factors
D 100022252 TRNT1; tRNA nucleotidyl transferase 1 K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D 100016063 RTCB; RNA 2',3'-cyclic phosphate and 5'-OH ligase K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D 100028509 LARS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 100029820 LARS2; leucyl-tRNA synthetase 2, mitochondrial K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 100032507 PARS2; prolyl-tRNA synthetase 2, mitochondrial (putative) K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D 100026880 YARS2; tyrosyl-tRNA synthetase 2 K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 100025987 YARS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 100027731 tyrosine--tRNA ligase, mitochondrial-like K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 100018040 WARS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 100012545 WARS2; tryptophanyl tRNA synthetase 2, mitochondrial K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 100021039 TARSL2; threonyl-tRNA synthetase like 2 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 100021284 TARS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 100017092 TARS2; threonyl-tRNA synthetase 2, mitochondrial (putative) K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 100029867 IARS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 100024337 IARS2; isoleucyl-tRNA synthetase 2, mitochondrial K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 100029118 KARS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D 100029003 lysine--tRNA ligase-like K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D 100011180 AARS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 100013354 AARS2; alanyl-tRNA synthetase 2, mitochondrial K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 100023525 VARS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D 100024455 VARS2; valyl-tRNA synthetase 2, mitochondrial K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D 100029705 MARS2; methionyl-tRNA synthetase 2, mitochondrial K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 100029990 SARS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 100619616 SARS2; seryl-tRNA synthetase 2, mitochondrial K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 100021040 DARS2; aspartyl-tRNA synthetase 2, mitochondrial K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 100015261 CARS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 100619335 CARS2; cysteinyl-tRNA synthetase 2, mitochondrial (putative) K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 100617355 EARS2; glutamyl-tRNA synthetase 2, mitochondrial K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D 100020835 QARS; glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D 100030898 arginine--tRNA ligase, cytoplasmic-like K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 100019290 RARS2; arginyl-tRNA synthetase 2, mitochondrial K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 100026083 arginine--tRNA ligase, cytoplasmic K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 100027432 FARSA; phenylalanyl-tRNA synthetase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 100028212 FARS2; phenylalanyl-tRNA synthetase 2, mitochondrial K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 100015798 FARSB; phenylalanyl-tRNA synthetase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D 100026449 HARS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 100026483 HARS2; histidyl-tRNA synthetase 2, mitochondrial K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 100016329 NARS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 100027168 NARS2; asparaginyl-tRNA synthetase 2, mitochondrial (putative) K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
C Trans-editing factors
D 100031436 DTD1; D-tyrosyl-tRNA deacylase 1 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 100012824 DTD2; D-tyrosyl-tRNA deacylase 2 (putative) K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 100010440 AARSD1; alanyl-tRNA synthetase domain containing 1 K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferases
C Methyltransferases
D 100031502 METTL1; methyltransferase like 1 K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D 100020108 TRMO; tRNA methyltransferase O K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D 100028468 PUS1; pseudouridylate synthase 1 K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D 100027192 TRUB1; TruB pseudouridine synthase family member 1 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D 100018668 PUS7; pseudouridylate synthase 7 (putative) K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D 100032517 NFS1; NFS1, cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
D 100029708 TP53RK; TP53 regulating kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D 100021300 OSGEPL1; O-sialoglycoprotein endopeptidase like 1 K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D 100022836 OSGEP; O-sialoglycoprotein endopeptidase K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
C Other tRNA modification factors
D 100021331 MTO1; mitochondrial tRNA translation optimization 1 K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D 100032056 TRIT1; tRNA isopentenyltransferase 1 K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D 100032241 PTS; 6-pyruvoyltetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D 100011764 SEPHS1; selenophosphate synthetase 1 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 100024928 SEPHS2; selenophosphate synthetase 2 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 100031786 YRDC; yrdC N6-threonylcarbamoyltransferase domain containing K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
B tRNA degradation factors
C 100033336 PNPT1; polyribonucleotide nucleotidyltransferase 1 K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C 100016855 ISG20; interferon stimulated exonuclease gene 20 K12579 ISG20; interferon-stimulated gene 20 kDa protein [EC:3.1.13.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024