+D GENES KO #

  KEGG Orthology (KO) - Mesoplasma florum L1

% ! A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:mfl00010] D Mfl497 glucose kinase K25026 glk; glucokinase [EC:2.7.1.2] D Mfl254 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Mfl174 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Mfl644 fructose-biphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Mfl504 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D Mfl578 glyceraldehyde 3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D Mfl577 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Mfl502 phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Mfl468 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Mfl175 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Mfl039 pyruvate dehydrogenase E1 alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Mfl040 pyruvate dehydrogenase E1 beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Mfl041 dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (E2) K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Mfl042 dihydrolipate dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Mfl596 L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D Mfl259 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase K00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9] D Mfl430 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl617 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl011 beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl012 beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl425 beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl313 beta-glucosidase/alpha xylosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl034 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl615 beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl009 beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl187 glucose-specific PTS system IIA component K02777 crr; sugar PTS system EIIA component [EC:2.7.1.-] D Mfl214 glucose-specific PTS system IIABC component K02779 ptsG; glucose PTS system EIICB or EIICBA component [EC:2.7.1.199] C 00020 Citrate cycle (TCA cycle) [PATH:mfl00020] D Mfl042 dihydrolipate dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Mfl039 pyruvate dehydrogenase E1 alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Mfl040 pyruvate dehydrogenase E1 beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Mfl041 dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (E2) K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] C 00030 Pentose phosphate pathway [PATH:mfl00030] D Mfl254 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Mfl223 pentose-5-phosphate-3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D Mfl640 pentose-5-phosphate-3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D Mfl349 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D Mfl105 ribose 5-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] D Mfl121 deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4] D Mfl639 deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4] D Mfl642 ribokinase K00852 rbsK; ribokinase [EC:2.7.1.15] D Mfl076 phosphoribosylpyrophosphate synthetase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Mfl259 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase K00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9] D Mfl644 fructose-biphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Mfl174 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] C 00040 Pentose and glucuronate interconversions D Mfl223 pentose-5-phosphate-3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D Mfl640 pentose-5-phosphate-3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] C 00051 Fructose and mannose metabolism [PATH:mfl00051] D Mfl514 fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D Mfl120 phosphomannomutase/phosphoglucomutase homolog K01840 manB; phosphomannomutase [EC:5.4.2.8] D Mfl174 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Mfl180 1-phosphofructokinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56] D Mfl644 fructose-biphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Mfl504 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D Mfl105 ribose 5-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] D Mfl181 fructose-specific PTS system IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] C 00052 Galactose metabolism [PATH:mfl00052] D Mfl497 glucose kinase K25026 glk; glucokinase [EC:2.7.1.2] D Mfl174 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Mfl515 sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D Mfl526 sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] C 00053 Ascorbate and aldarate metabolism D Mfl643 unknown substrate putative PTS system IIC component K03475 ulaA; ascorbate PTS system EIIC component C 00500 Starch and sucrose metabolism [PATH:mfl00500] D Mfl516 sucrose PTS system IIBC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D Mfl515 sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D Mfl526 sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D Mfl430 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl617 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl011 beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl012 beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl425 beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl313 beta-glucosidase/alpha xylosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl034 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl615 beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl009 beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D Mfl187 glucose-specific PTS system IIA component K02777 crr; sugar PTS system EIIA component [EC:2.7.1.-] D Mfl527 sucrose PTS system IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D Mfl426 trehalose/sucrose/beta-glucoside PTS system IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D Mfl431 trehalose/sucrose/beta-glucoside PTS system IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D Mfl500 trehalose PTS system IIABC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D Mfl499 trehalose-6-phosphate hydrolase K01226 treC; trehalose-6-phosphate hydrolase [EC:3.2.1.93] D Mfl497 glucose kinase K25026 glk; glucokinase [EC:2.7.1.2] D Mfl254 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Mfl514 fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:mfl00520] D Mfl187 glucose-specific PTS system IIA component K02777 crr; sugar PTS system EIIA component [EC:2.7.1.-] D Mfl514 fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D Mfl214 glucose-specific PTS system IIABC component K02779 ptsG; glucose PTS system EIICB or EIICBA component [EC:2.7.1.199] D Mfl497 glucose kinase K25026 glk; glucokinase [EC:2.7.1.2] D Mfl254 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Mfl120 phosphomannomutase/phosphoglucomutase homolog K01840 manB; phosphomannomutase [EC:5.4.2.8] C 00620 Pyruvate metabolism [PATH:mfl00620] D Mfl039 pyruvate dehydrogenase E1 alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Mfl040 pyruvate dehydrogenase E1 beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Mfl041 dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (E2) K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Mfl042 dihydrolipate dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Mfl044 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D Mfl043 phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D Mfl175 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Mfl596 L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D Mfl656 Zn-dependent hydrolase/glyoxylase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:mfl00630] D Mfl106 serine hydroxymethyl transferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Mfl042 dihydrolipate dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] C 00640 Propanoate metabolism [PATH:mfl00640] D Mfl044 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D Mfl043 phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D Mfl042 dihydrolipate dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Mfl596 L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] C 00650 Butanoate metabolism C 00660 C5-Branched dibasic acid metabolism C 00562 Inositol phosphate metabolism [PATH:mfl00562] D Mfl208 oxioreductase K22230 iolU; scyllo-inositol 2-dehydrogenase (NADP+) [EC:1.1.1.-] D Mfl504 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:mfl00190] D Mfl113 ATP synthase alpha chain K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D Mfl115 ATP synthase beta chain K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D Mfl114 ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D Mfl112 ATP synthase delta chain K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D Mfl116 ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D Mfl109 ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a D Mfl111 ATP synthase subunit B K02109 ATPF0B; F-type H+-transporting ATPase subunit b D Mfl110 ATP synthase subunit C K02110 ATPF0C; F-type H+-transporting ATPase subunit c D Mfl544 inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation in photosynthetic organisms C 00720 Carbon fixation pathways in prokaryotes C 00680 Methane metabolism [PATH:mfl00680] D Mfl106 serine hydroxymethyl transferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Mfl468 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Mfl644 fructose-biphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Mfl174 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Mfl044 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D Mfl043 phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D Mfl502 phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] C 00910 Nitrogen metabolism C 00920 Sulfur metabolism D Mfl488 exopolyphosphatase-like K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] D Mfl636 exopolyphosphatase-like K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis D Mfl593 acyl carrier protein I precurser K02078 acpP; acyl carrier protein C 00062 Fatty acid elongation C 00071 Fatty acid degradation C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism [PATH:mfl00561] D Mfl230 fatty acid/phospholipid synthesis protein K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D Mfl337 unknown transmembrane protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D Mfl382 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C 00564 Glycerophospholipid metabolism [PATH:mfl00564] D Mfl200 NAD-dependent glycerol-3-phosphate dehydrogenase K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] D Mfl337 unknown transmembrane protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D Mfl382 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D Mfl286 CDP-diglyceride synthetase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41] D Mfl663 phosphatidylglycerophosphate synthase K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5] D Mfl626 cardiolipin synthetase K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:mfl00230] D Mfl076 phosphoribosylpyrophosphate synthetase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Mfl075 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D Mfl276 adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D Mfl665 purine-nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] D Mfl463 hypoxanthine-guanine phosphoribosyltransferase K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] D Mfl343 IMP dehydrogenase (Inosine-5'-monophosphate dehydrogenase) K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D Mfl375 putative xanthosine triphosphatepyrophosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D Mfl342 GMP synthase (glutamine hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Mfl170 GMP reductase K00364 guaC; GMP reductase [EC:1.7.1.7] D Mfl195 guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8] D Mfl528 ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Mfl530 ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D Mfl278 guanosine-3', 5'-bis(diphosphate)3'-pyrophosphohydrolase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D Mfl074 adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D Mfl215 adenosine deaminase K01488 add; adenosine deaminase [EC:3.5.4.4] D Mfl239 putative phosphoesterase-like protein K09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16] D Mfl144 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] C 00240 Pyrimidine metabolism [PATH:mfl00240] D Mfl556 uridine monophosphate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D Mfl648 CTP synthase (UTP-ammonia ligase) K01937 pyrG; CTP synthase [EC:6.3.4.2] D Mfl198 putative cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D Mfl306 uridine kinase K00876 udk; uridine kinase [EC:2.7.1.48] D Mfl107 uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9] D Mfl239 putative phosphoesterase-like protein K09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16] D Mfl143 cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5] D Mfl466 cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5] D Mfl528 ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Mfl530 ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D Mfl385 deoxycytidylate deaminase K01493 comEB; dCMP deaminase [EC:3.5.4.12] D Mfl676 thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D Mfl119 thymidine phosphorylase K00758 deoA; thymidine phosphorylase [EC:2.4.2.4] D Mfl635 thymidine, deoxyuridine kinase K00857 tdk; thymidine kinase [EC:2.7.1.21] D Mfl419 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:mfl00250] D Mfl074 adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D Mfl075 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] C 00260 Glycine, serine and threonine metabolism [PATH:mfl00260] D Mfl106 serine hydroxymethyl transferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Mfl502 phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Mfl042 dihydrolipate dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] C 00270 Cysteine and methionine metabolism [PATH:mfl00270] D Mfl240 S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D Mfl372 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase (purine nucleosidase) K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9] D Mfl308 modification methylase Sau3AI (GATC cytosine-specific methyltransferase) K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mfl304 deoxycytosine methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mfl596 L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] C 00280 Valine, leucine and isoleucine degradation [PATH:mfl00280] D Mfl042 dihydrolipate dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] C 00290 Valine, leucine and isoleucine biosynthesis C 00300 Lysine biosynthesis D Mfl437 arginine catabolism aminotransferase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] C 00310 Lysine degradation D Mfl042 dihydrolipate dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] C 00220 Arginine biosynthesis C 00330 Arginine and proline metabolism [PATH:mfl00330] D Mfl045 1-pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2] C 00340 Histidine metabolism C 00350 Tyrosine metabolism C 00360 Phenylalanine metabolism C 00380 Tryptophan metabolism D Mfl042 dihydrolipate dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism C 00430 Taurine and hypotaurine metabolism [PATH:mfl00430] D Mfl043 phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D Mfl044 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:mfl00450] D Mfl248 similar to selenocysteine lyase, class V pyridoxal phosphate aminotransferase, cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D Mfl064 thioredoxin reductase NADPH K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D Mfl036 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism D Mfl106 serine hydroxymethyl transferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism C 00480 Glutathione metabolism [PATH:mfl00480] D Mfl070 cytosol aminopeptidase (leucine aminopeptidase) K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D Mfl071 cytosol aminopeptidase (leucine aminopeptidase) K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D Mfl072 cytosol aminopeptidase (leucine aminopeptidase) K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation C 00540 Lipopolysaccharide biosynthesis C 00542 O-Antigen repeat unit biosynthesis C 00541 O-Antigen nucleotide sugar biosynthesis D Mfl120 phosphomannomutase/phosphoglucomutase homolog K01840 manB; phosphomannomutase [EC:5.4.2.8] C 00550 Peptidoglycan biosynthesis C 00552 Teichoic acid biosynthesis C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:mfl00730] D Mfl584 thiamin biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D Mfl222 conserved GTPase K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D Mfl224 unknown protein K00949 thiN; thiamine pyrophosphokinase [EC:2.7.6.2] D Mfl144 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] C 00740 Riboflavin metabolism [PATH:mfl00740] D Mfl503 cof-like hydrolase, HAD-superfamily K21064 ycsE; 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.104] D Mfl334 riboflavin kinase K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] D Mfl283 riboflavin kinase/FAD synthase K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] C 00750 Vitamin B6 metabolism C 00760 Nicotinate and nicotinamide metabolism [PATH:mfl00760] D Mfl588 nicotinic acid phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21] D Mfl665 purine-nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] D Mfl373 deamido-NAD(+) pyrophosphorylase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18] D Mfl521 NH3-dependent NAD+ synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5] D Mfl205 competence-damage inducible protein K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42] D Mfl340 nicotinamidase/pyrazinamidase K08281 pncA; nicotinamidase/pyrazinamidase [EC:3.5.1.19 3.5.1.-] D Mfl193 putative NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] C 00770 Pantothenate and CoA biosynthesis [PATH:mfl00770] D Mfl281 dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24] D Mfl384 holo-acyl carrier protein synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7] C 00780 Biotin metabolism C 00785 Lipoic acid metabolism [PATH:mfl00785] D Mfl038 lipoate-protein ligase K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D Mfl042 dihydrolipate dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Mfl039 pyruvate dehydrogenase E1 alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Mfl040 pyruvate dehydrogenase E1 beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Mfl041 dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (E2) K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] C 00790 Folate biosynthesis [PATH:mfl00790] D Mfl272 unknown protein K22391 E3.5.4.16; GTP cyclohydrolase I [EC:3.5.4.16] D Mfl383 dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D Mfl060 putative folyl-polyglutamate synthetase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] C 00670 One carbon pool by folate [PATH:mfl00670] D Mfl383 dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D Mfl167 methylenetetrahydrofolate dehydrogenase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D Mfl106 serine hydroxymethyl transferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Mfl409 methyonyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D Mfl419 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] D Mfl250 5-formyltetrahydrofolate cyclo-ligase family protein K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] C 00830 Retinol metabolism C 00860 Porphyrin metabolism D Mfl651 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation C 00907 Pinene, camphor and geraniol degradation C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D Mfl349 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis C 00332 Carbapenem biosynthesis C 00261 Monobactam biosynthesis C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis D Mfl497 glucose kinase K25026 glk; glucokinase [EC:2.7.1.2] C 00524 Neomycin, kanamycin and gentamicin biosynthesis D Mfl497 glucose kinase K25026 glk; glucokinase [EC:2.7.1.2] C 00525 Acarbose and validamycin biosynthesis C 00401 Novobiocin biosynthesis C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis C 00333 Prodigiosin biosynthesis C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics D Mfl593 acyl carrier protein I precurser K02078 acpP; acyl carrier protein C 00999 Biosynthesis of various plant secondary metabolites D Mfl240 S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation C 00627 Aminobenzoate degradation C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation C 00361 Chlorocyclohexane and chlorobenzene degradation C 00623 Toluene degradation C 00622 Xylene degradation C 00633 Nitrotoluene degradation C 00642 Ethylbenzene degradation C 00643 Styrene degradation C 00791 Atrazine degradation C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation C 00626 Naphthalene degradation C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:mfl03020] D Mfl598 DNA-directed RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D Mfl597 DNA-directed RNA polymerase beta subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D Mfl150 DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D Mfl649 RNA polymerase subunit delta K03048 rpoE; DNA-directed RNA polymerase subunit delta C 03022 Basal transcription factors C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:mfl03010] D Mfl561 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D Mfl129 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D Mfl586 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D Mfl140 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D Mfl080 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6 D Mfl623 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D Mfl137 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D Mfl492 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D Mfl122 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D Mfl149 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D Mfl624 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D Mfl148 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D Mfl136 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D Mfl284 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D Mfl542 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D Mfl132 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D Mfl082 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D Mfl127 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D Mfl368.1 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20 D Mfl362.1 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D Mfl608 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D Mfl126 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D Mfl123 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D Mfl124 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4 D Mfl135 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D Mfl138 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D Mfl601 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D Mfl083 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9 D Mfl602 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D Mfl609 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D Mfl493 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D Mfl133 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D Mfl141 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D Mfl130 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D Mfl151 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D Mfl139 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D Mfl539 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D Mfl190 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D Mfl441 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D Mfl128 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D Mfl125 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D Mfl134 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D Mfl439 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D Mfl227 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D Mfl131 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D Mfl638 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D Mfl396 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D Mfl089 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D Mfl380 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D Mfl682.1 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34 D Mfl189 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35 D Mfl147 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36 C 00970 Aminoacyl-tRNA biosynthesis [PATH:mfl00970] D Mflt023 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Mflt027 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Mflt025 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Mflt02 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Mflt018 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Mflt026 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Mflt012 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Mflt03 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Mflt09 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Mflt01 tRNA-His K14226 tRNA-His; tRNA His D Mflt016 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Mflt08 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Mflt010 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Mflt07 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Mflt06 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Mflt011 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Mflt022 tRNA-Met K14230 tRNA-Met; tRNA Met D Mflt021 tRNA-Met K14230 tRNA-Met; tRNA Met D Mflt019 tRNA-Met K14230 tRNA-Met; tRNA Met D Mflt017 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D Mflt024 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Mflt020 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Mflt015 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Mflt05 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Mflt014 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Mflt028 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D Mflt013 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D Mflt04 tRNA-Val K14237 tRNA-Val; tRNA Val D Mflt029 tRNA-Sec K14238 tRNA-Sec; tRNA Sec D Mfl651 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Mfl162 Glu-tRNA amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D Mfl163 Glu-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D Mfl161 Glu-tRNA amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D Mfl613 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Mfl365 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Mfl480 asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D Mfl268 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Mfl177 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Mfl017 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Mfl087 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Mfl036 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Mfl409 methyonyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D Mfl355 valyl tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Mfl490 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Mfl389 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Mfl030 lysyl tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D Mfl554 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Mfl476 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Mfl366 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Mfl399 phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Mfl398 phenylalanyl-tRNA synthetase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Mfl587 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Mfl192 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:mfl03060] D Mfl142 preprotein translocase K03076 secY; preprotein translocase subunit SecY D Mfl090 preprotein translocase K03073 secE; preprotein translocase subunit SecE D Mfl068 preprotein translocase K03075 secG; preprotein translocase subunit SecG D Mfl275 protein-export membrane protein K12257 secDF; SecD/SecF fusion protein D Mfl681 predicted inner membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D Mfl057 preprotein translocase K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Mfl479 signal recognition particle (signal binding protein) K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Mfl237 signal recognition particle, cell division protein GTPase K03110 ftsY; fused signal recognition particle receptor D Mfl388 lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:mfl04122] D Mfl412 tRNA(5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D Mfl584 thiamin biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] C 03050 Proteasome C 03018 RNA degradation [PATH:mfl03018] D Mfl468 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Mfl209 virulence associated protein, ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1] D Mfl525 ATP-dependent RNA helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Mfl207 predicted HD-superfamily hydrolase K18682 rny; ribonucrease Y [EC:3.1.-.-] D Mfl570 putative metallo-beta lactamase hydrolase K12574 rnj; ribonuclease J [EC:3.1.-.-] D Mfl092 putative metallo-beta lactamase hydrolase K12574 rnj; ribonuclease J [EC:3.1.-.-] D Mfl174 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Mfl415 hsp70 chaperone K04043 dnaK; molecular chaperone DnaK B B 09124 Replication and repair C 03030 DNA replication [PATH:mfl03030] D Mfl583 DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Mfl288 DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D Mfl678 DNA polymerase III gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Mfl675 DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Mfl368 unknown protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Mfl002 DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Mfl084 DNA replication priming helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D Mfl269 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D Mfl081 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Mfl537 Ribonuclease HII, primer excision K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Mfl582 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Mfl160 DNA ligase, polydeoxyribonucleotide synthase NAD+ K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03410 Base excision repair [PATH:mfl03410] D Mfl243 uracil-DNA glycosylase 1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D Mfl581 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D Mfl277 DNA-3-methyladenine glycosidase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D Mfl333 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D Mfl582 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Mfl160 DNA ligase, polydeoxyribonucleotide synthase NAD+ K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03420 Nucleotide excision repair [PATH:mfl03420] D Mfl059 repair endonuclease subunit A K03701 uvrA; excinuclease ABC subunit A D Mfl058 repair endonuclease subunit B K03702 uvrB; excinuclease ABC subunit B D Mfl101 repair endonuclease subunit C K03703 uvrC; excinuclease ABC subunit C D Mfl566 repair endonuclease ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Mfl582 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Mfl160 DNA ligase, polydeoxyribonucleotide synthase NAD+ K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03430 Mismatch repair [PATH:mfl03430] D Mfl566 repair endonuclease ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Mfl331 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D Mfl330 unknown protein K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D Mfl081 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Mfl583 DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Mfl288 DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D Mfl002 DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Mfl678 DNA polymerase III gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Mfl368 unknown protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Mfl675 DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Mfl160 DNA ligase, polydeoxyribonucleotide synthase NAD+ K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03440 Homologous recombination [PATH:mfl03440] D Mfl081 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Mfl267 DNA repair/recombination protein K03584 recO; DNA repair protein RecO (recombination protein O) D Mfl677 recombination protein K06187 recR; recombination protein RecR D Mfl206 recombinase A K03553 recA; recombination protein RecA D Mfl582 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Mfl421 holliday junction DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA D Mfl420 holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D Mfl322 exodeoxyribonuclease V K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D Mfl583 DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Mfl288 DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D Mfl002 DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Mfl678 DNA polymerase III gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Mfl368 unknown protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Mfl675 DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] C 03450 Non-homologous end-joining C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus and Lyssavirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:mfl02010] D Mfl509 spermidine/putrescine ABC transporter permease component K11070 potC; spermidine/putrescine transport system permease protein D Mfl510 spermidine/putrescine ABC transporter permease component K11071 potB; spermidine/putrescine transport system permease protein D Mfl511 spermidine/putrescine ABC transporter ATP-binding component K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11] D Mfl024 sn-glycerol-3-phosphate ABC transporter ATP-binding component K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D Mfl669 xylose ABC transporter periplasmic binding component K07335 bmpA; basic membrane protein A and related proteins D Mfl667 ribose ABC transporter permease component K23535 nupB; general nucleoside transport system permease protein D Mfl666 ribose ABC transporter permease component K23536 nupC; general nucleoside transport system permease protein D Mfl668 ribose ABC transporter ATP-binding component K23537 nupA; general nucleoside transport system ATP-binding protein D Mfl233 phosphate ABC transporter transmembrane component K02040 pstS; phosphate transport system substrate-binding protein D Mfl234 phosphate ABC transporter permease component K02037 pstC; phosphate transport system permease protein D Mfl235 phosphate ABC transporter ATP-binding component K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Mfl573 unknown lipoprotein K02044 phnD; phosphonate transport system substrate-binding protein D Mfl571 phosphonate ABC transporter permease component K02042 phnE; phosphonate transport system permease protein D Mfl572 phosphonate ABC transporter ATP-binding component K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2] D Mfl098 oligopeptide ABC transporter periplasmic binding component K15580 oppA; oligopeptide transport system substrate-binding protein D Mfl094 oligopeptide ABC transporter permease component K15581 oppB; oligopeptide transport system permease protein D Mfl095 oligopeptide ABC transporter permease component K15582 oppC; oligopeptide transport system permease protein D Mfl096 oligopeptide ABC transporter ATP-binding component K15583 oppD; oligopeptide transport system ATP-binding protein D Mfl097 oligopeptide ABC transporter ATP-binding component K10823 oppF; oligopeptide transport system ATP-binding protein D Mfl154 cobalt ABC transporter permease component K16785 ecfT; energy-coupling factor transport system permease protein D Mfl152 cobalt ABC transporter ATP-binding component K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D Mfl153 cobalt ABC transporter ATP-binding component K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] C 02060 Phosphotransferase system (PTS) [PATH:mfl02060] D Mfl519 phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] D Mfl565 phosphotransferase system phosphohistidine-containing protein K02784 ptsH; phosphocarrier protein HPr D Mfl187 glucose-specific PTS system IIA component K02777 crr; sugar PTS system EIIA component [EC:2.7.1.-] D Mfl214 glucose-specific PTS system IIABC component K02779 ptsG; glucose PTS system EIICB or EIICBA component [EC:2.7.1.199] D Mfl516 sucrose PTS system IIBC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D Mfl619 unknown substrate PTS system IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D Mfl312 beta-glucoside PTS system IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D Mfl318 beta-glucoside PTS system IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D Mfl008 beta-glucoside PTS system IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D Mfl033 beta-glucoside PTS system IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D Mfl527 sucrose PTS system IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D Mfl426 trehalose/sucrose/beta-glucoside PTS system IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D Mfl431 trehalose/sucrose/beta-glucoside PTS system IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D Mfl500 trehalose PTS system IIABC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D Mfl643 unknown substrate putative PTS system IIC component K03475 ulaA; ascorbate PTS system EIIC component D Mfl181 fructose-specific PTS system IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D Mfl180 1-phosphofructokinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56] C 03070 Bacterial secretion system [PATH:mfl03070] D Mfl275 protein-export membrane protein K12257 secDF; SecD/SecF fusion protein D Mfl090 preprotein translocase K03073 secE; preprotein translocase subunit SecE D Mfl068 preprotein translocase K03075 secG; preprotein translocase subunit SecG D Mfl142 preprotein translocase K03076 secY; preprotein translocase subunit SecY D Mfl681 predicted inner membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D Mfl057 preprotein translocase K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Mfl237 signal recognition particle, cell division protein GTPase K03110 ftsY; fused signal recognition particle receptor D Mfl479 signal recognition particle (signal binding protein) K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] B B 09132 Signal transduction C 02020 Two-component system [PATH:mfl02020] D Mfl233 phosphate ABC transporter transmembrane component K02040 pstS; phosphate transport system substrate-binding protein D Mfl001 chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:mfl02024] D Mfl098 oligopeptide ABC transporter periplasmic binding component K15580 oppA; oligopeptide transport system substrate-binding protein D Mfl094 oligopeptide ABC transporter permease component K15581 oppB; oligopeptide transport system permease protein D Mfl095 oligopeptide ABC transporter permease component K15582 oppC; oligopeptide transport system permease protein D Mfl096 oligopeptide ABC transporter ATP-binding component K15583 oppD; oligopeptide transport system ATP-binding protein D Mfl097 oligopeptide ABC transporter ATP-binding component K10823 oppF; oligopeptide transport system ATP-binding protein D Mfl681 predicted inner membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D Mfl275 protein-export membrane protein K12257 secDF; SecD/SecF fusion protein D Mfl090 preprotein translocase K03073 secE; preprotein translocase subunit SecE D Mfl068 preprotein translocase K03075 secG; preprotein translocase subunit SecG D Mfl142 preprotein translocase K03076 secY; preprotein translocase subunit SecY D Mfl057 preprotein translocase K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Mfl237 signal recognition particle, cell division protein GTPase K03110 ftsY; fused signal recognition particle receptor D Mfl479 signal recognition particle (signal binding protein) K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis C 02040 Flagellar assembly D Mfl270 RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D Mfl468 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance D Mfl098 oligopeptide ABC transporter periplasmic binding component K15580 oppA; oligopeptide transport system substrate-binding protein D Mfl094 oligopeptide ABC transporter permease component K15581 oppB; oligopeptide transport system permease protein D Mfl095 oligopeptide ABC transporter permease component K15582 oppC; oligopeptide transport system permease protein D Mfl096 oligopeptide ABC transporter ATP-binding component K15583 oppD; oligopeptide transport system ATP-binding protein D Mfl097 oligopeptide ABC transporter ATP-binding component K10823 oppF; oligopeptide transport system ATP-binding protein C 01502 Vancomycin resistance C 01503 Cationic antimicrobial peptide (CAMP) resistance B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:mfl01000] C 01001 Protein kinases [BR:mfl01001] D Mfl221 probable serine/threonine protein kinase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] C 01009 Protein phosphatases and associated proteins [BR:mfl01009] D Mfl174 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Mfl220 serine/threonine phosphatase K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16] C 01002 Peptidases and inhibitors [BR:mfl01002] D Mfl388 lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] D Mfl342 GMP synthase (glutamine hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Mfl263 putative intracellular protease/amidase K03152 thiJ; protein deglycase [EC:3.5.1.124] D Mfl564 CAAX amino terminal membrane bound protease K07052 K07052; CAAX protease family protein D Mfl241 putative membrane metallo endopeptidase K07386 pepO; putative endopeptidase [EC:3.4.24.-] D Mfl070 cytosol aminopeptidase (leucine aminopeptidase) K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D Mfl071 cytosol aminopeptidase (leucine aminopeptidase) K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D Mfl072 cytosol aminopeptidase (leucine aminopeptidase) K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D Mfl437 arginine catabolism aminotransferase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D Mfl145 methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D Mfl379 Xaa-Pro-dipeptidase K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9] D Mfl672 cell division protein K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D Mfl287 probable membrane associated Zn-dependent protease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] D Mfl404 class III heat shock DNA-binding ATP dependent Lon protease K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] C 01003 Glycosyltransferases C 01005 Lipopolysaccharide biosynthesis proteins C 01011 Peptidoglycan biosynthesis and degradation proteins C 01004 Lipid biosynthesis proteins [BR:mfl01004] D Mfl230 fatty acid/phospholipid synthesis protein K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D Mfl337 unknown transmembrane protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D Mfl382 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases C 01007 Amino acid related enzymes [BR:mfl01007] D Mfl651 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Mfl587 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Mfl192 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D Mfl087 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Mfl554 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Mfl036 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Mfl389 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Mfl355 valyl tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Mfl490 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Mfl030 lysyl tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D Mfl365 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Mfl480 asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D Mfl366 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Mfl268 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Mfl017 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Mfl476 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Mfl177 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Mfl613 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Mfl399 phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Mfl398 phenylalanyl-tRNA synthetase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins [BR:mfl00194] D Mfl116 ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D Mfl115 ATP synthase beta chain K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D Mfl114 ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D Mfl113 ATP synthase alpha chain K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D Mfl112 ATP synthase delta chain K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D Mfl111 ATP synthase subunit B K02109 ATPF0B; F-type H+-transporting ATPase subunit b D Mfl110 ATP synthase subunit C K02110 ATPF0C; F-type H+-transporting ATPase subunit c D Mfl109 ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:mfl03000] D Mfl308 modification methylase Sau3AI (GATC cytosine-specific methyltransferase) K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mfl304 deoxycytosine methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mfl179 fru repressor K03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor D Mfl501 trehalose operon repressor, repressor of treA,B,C K03484 scrR; LacI family transcriptional regulator, sucrose operon repressor D Mfl517 putative sucrose repressor K11922 mngR; GntR family transcriptional regulator, mannosyl-D-glycerate transport/metabolism system repressor D Mfl171 HTH transcriptional regulator merR family K21745 adhR; MerR family transcriptional regulator, aldehyde-responsive regulator D Mfl592 ferric uptake regulation protein K03711 fur; Fur family transcriptional regulator, ferric uptake regulator D Mfl417 heat inducible transcription repressor K03705 hrcA; heat-inducible transcriptional repressor D Mfl395 cell division protein K03925 mraZ; transcriptional regulator MraZ C 03021 Transcription machinery [BR:mfl03021] D Mfl150 DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D Mfl598 DNA-directed RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D Mfl597 DNA-directed RNA polymerase beta subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D Mfl649 RNA polymerase subunit delta K03048 rpoE; DNA-directed RNA polymerase subunit delta D Mfl270 RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor D Mfl292 transcription terminator K02600 nusA; transcription termination/antitermination protein NusA D Mfl332 transcription termination factor K03625 nusB; transcription antitermination protein NusB D Mfl091 transcription antitermination factor K02601 nusG; transcription termination/antitermination protein NusG D Mfl102 transcription elongation factor K03624 greA; transcription elongation factor GreA C 03019 Messenger RNA biogenesis [BR:mfl03019] D Mfl231 ribonuclease III, dsRNA-specific ribonuclease K03685 rnc; ribonuclease III [EC:3.1.26.3] D Mfl570 putative metallo-beta lactamase hydrolase K12574 rnj; ribonuclease J [EC:3.1.-.-] D Mfl092 putative metallo-beta lactamase hydrolase K12574 rnj; ribonuclease J [EC:3.1.-.-] D Mfl207 predicted HD-superfamily hydrolase K18682 rny; ribonucrease Y [EC:3.1.-.-] D Mfl209 virulence associated protein, ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1] D Mfl244 cmp-binding factor-1 K03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-] D Mfl525 ATP-dependent RNA helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Mfl273 ATP-dependent RNA helicase K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7] D Mfl468 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Mfl174 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Mfl415 hsp70 chaperone K04043 dnaK; molecular chaperone DnaK C 03041 Spliceosome C 03011 Ribosome [BR:mfl03011] D Mfl561 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D Mfl129 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D Mfl586 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D Mfl140 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D Mfl080 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6 D Mfl623 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D Mfl137 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D Mfl492 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D Mfl122 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D Mfl149 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D Mfl624 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D Mfl148 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D Mfl136 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D Mfl284 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D Mfl542 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D Mfl132 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D Mfl082 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D Mfl127 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D Mfl368.1 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20 D Mfl362.1 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D Mfl608 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D Mfl126 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D Mfl123 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D Mfl124 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4 D Mfl135 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D Mfl138 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D Mfl083 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9 D Mfl602 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D Mfl609 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D Mfl601 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D Mfl493 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D Mfl133 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D Mfl141 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D Mfl130 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D Mfl151 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D Mfl139 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D Mfl539 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D Mfl190 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D Mfl441 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D Mfl128 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D Mfl125 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D Mfl134 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D Mfl439 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D Mfl227 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D Mfl131 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D Mfl638 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D Mfl396 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D Mfl089 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D Mfl380 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D Mfl682.1 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34 D Mfl189 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35 D Mfl147 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36 C 03009 Ribosome biogenesis [BR:mfl03009] D Mfl231 ribonuclease III, dsRNA-specific ribonuclease K03685 rnc; ribonuclease III [EC:3.1.26.3] D Mfl266 GTP-binding protein, cell cycle control K03595 era; GTPase D Mfl522 conserved GTPase K03979 obgE; GTPase [EC:3.6.5.-] D Mfl292 transcription terminator K02600 nusA; transcription termination/antitermination protein NusA D Mfl332 transcription termination factor K03625 nusB; transcription antitermination protein NusB D Mfl091 transcription antitermination factor K02601 nusG; transcription termination/antitermination protein NusG D Mfl005 16S rRNA (adenosine-N6,N6-)-dimethyltransferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D Mfl196 tRNA and rRNA cytosine-C5-methylases K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D Mfl194 N6-adenine-specific methylase K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171] D Mfl303 unknown protein K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193] D Mfl662 glucose-inhibited methyltransferase K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D Mfl394 cell membrane substrate S-adenosyl-methyltransferase K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199] D Mfl103 putative tetrapyrrole methylase K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198] D Mfl329 rRNA methylase K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227] D Mfl088 rRNA methylase K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185] D Mfl478 unknown protein K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177] D Mfl548 23S rRNA pseudouridine synthase K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22] D Mfl563 23S rRNA pseudouridine synthase K06179 rluC; 23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24] D Mfl387 23S rRNA/tRNA pseudouridine synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D Mfl541 16S rRNA processing protein K02860 rimM; 16S rRNA processing protein RimM D Mfl464 possible Holliday junction resolvase K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-] D Mfl525 ATP-dependent RNA helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Mfl273 ATP-dependent RNA helicase K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7] D Mfl222 conserved GTPase K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D Mfl199 GTP-binding protein, cell cycle control K03977 engA; GTPase D Mfl538 predicted GTPase K14540 rbgA; ribosome biogenesis GTPase A D Mfl351 predicted GTPase K06948 yqeH; 30S ribosome assembly GTPase D Mfl630 putative translation factor K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D Mfl278 guanosine-3', 5'-bis(diphosphate)3'-pyrophosphohydrolase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D Mfl371 ribosome-binding factor A K02834 rbfA; ribosome-binding factor A D Mfl291 unknown protein K09748 rimP; ribosome maturation factor RimP D Mfl265 putative metal-dependent hydrolase K07042 ybeY; probable rRNA maturation factor D Mfl660 conserved GTPase K06942 ychF; ribosome-binding ATPase C 03016 Transfer RNA biogenesis [BR:mfl03016] D Mfl651 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Mfl476 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Mfl389 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Mfl490 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Mfl036 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Mfl554 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Mfl030 lysyl tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D Mfl365 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Mfl613 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Mfl480 asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D Mfl268 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Mfl177 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Mfl017 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Mfl087 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Mfl355 valyl tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Mfl366 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Mfl399 phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Mfl398 phenylalanyl-tRNA synthetase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Mfl587 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Mfl192 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D Mfl245 putative nucleotidyl hydrolase/transferase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D Mfl218 predicted S-adenosylmethionine-dependent methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] D Mfl155 tRNA pseudouridine synthase I K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D Mfl282 tRNA pseudouridine 5S synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D Mfl630 putative translation factor K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D Mfl014 tRNA modification GTPase K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-] D Mfl671 glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D Mfl682 ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5] D Mfl679 cytosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33] D Mfl029 tRNA dihydrouridine synthetase K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-] D Mfl242 glucose inhibited division protein C K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74] D Mfl532 glucose inhibited division protein C K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74] D Mfl540 tRNA guanine-N1-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D Mfl271 putative SAM-dependent methyltransferase K06967 trmK; tRNA (adenine22-N1)-methyltransferase [EC:2.1.1.217] D Mfl374 rRNA methyltransferase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207] D Mfl258 rRNA methylase K03437 spoU; RNA methyltransferase, TrmH family D Mfl412 tRNA(5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D Mfl584 thiamin biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D Mfl673 lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19] D Mfl494 putative glycoprotein endopeptidase K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB D Mfl484 glycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234] D Mfl495 conserved hypothetical protein, ATPase K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE D Mfl209 virulence associated protein, ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1] C 03012 Translation factors [BR:mfl03012] D Mfl295 translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2 D Mfl188 translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D Mfl560 translation elongation factor Ts K02357 tsf; elongation factor Ts D Mfl621 translation elongation factor Tu K02358 tuf; elongation factor Tu D Mfl622 translation elongation factor G K02355 fusA; elongation factor G D Mfl634 peptide chain release factor 1 K02835 prfA; peptide chain release factor 1 D Mfl555 ribosome recycling factor K02838 frr; ribosome recycling factor D Mfl633 polypeptide chain release factor methylase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D Mfl077 peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] D Mfl146 translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1 D Mfl407 translation elongation factor P K02356 efp; elongation factor P C 03110 Chaperones and folding catalysts [BR:mfl03110] D Mfl418 ATPase subunit of ATP-dependant protease K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB D Mfl415 hsp70 chaperone K04043 dnaK; molecular chaperone DnaK D Mfl414 heat shock protein chaperone K03686 dnaJ; molecular chaperone DnaJ D Mfl018 putative hsp33 redox-regulated chaperone K04083 hslO; molecular chaperone Hsp33 D Mfl416 hsp70 cofactor K03687 GRPE; molecular chaperone GrpE D Mfl672 cell division protein K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D Mfl109 ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a D Mfl178 thioredoxin K03671 TXN; thioredoxin C 04131 Membrane trafficking [BR:mfl04131] D Mfl578 glyceraldehyde 3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D Mfl175 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] C 04121 Ubiquitin system C 03051 Proteasome C 03032 DNA replication proteins [BR:mfl03032] D Mfl308 modification methylase Sau3AI (GATC cytosine-specific methyltransferase) K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mfl304 deoxycytosine methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mfl201 predicted histone-like DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D Mfl001 chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein D Mfl084 DNA replication priming helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D Mfl269 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D Mfl580 DNA replication priming helicase K03346 dnaB; replication initiation and membrane attachment protein D Mfl579 chromosomal replication initiator protein K11144 dnaI; primosomal protein DnaI D Mfl081 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Mfl583 DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Mfl288 DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D Mfl002 DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Mfl368 unknown protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Mfl675 DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Mfl678 DNA polymerase III gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Mfl537 Ribonuclease HII, primer excision K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Mfl582 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Mfl160 DNA ligase, polydeoxyribonucleotide synthase NAD+ K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Mfl007 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D Mfl006 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D Mfl310 DNA topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D Mfl309 DNA topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D Mfl654 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] C 03036 Chromosome and associated proteins [BR:mfl03036] D Mfl308 modification methylase Sau3AI (GATC cytosine-specific methyltransferase) K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mfl304 deoxycytosine methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mfl231 ribonuclease III, dsRNA-specific ribonuclease K03685 rnc; ribonuclease III [EC:3.1.26.3] D Mfl201 predicted histone-like DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D Mfl001 chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein D Mfl232 structural maintenance of chromosomes smc superfamily protein K03529 smc; chromosome segregation protein D Mfl550 chromosomal segregation/condensation protein K05896 scpA; segregation and condensation protein A D Mfl549 chromosomal segregation/condensation protein K06024 scpB; segregation and condensation protein B D Mfl100 DNA translocase (stage III sporulation protein E) K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family D Mfl392 cell division initiation protein K03531 ftsZ; cell division protein FtsZ D Mfl391 unknown protein K09772 sepF; cell division inhibitor SepF D Mfl003 actin-like protein K03569 mreB; rod shape-determining protein MreB and related proteins D Mfl310 DNA topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D Mfl309 DNA topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D Mfl671 glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D Mfl662 glucose-inhibited methyltransferase K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D Mfl242 glucose inhibited division protein C K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74] D Mfl532 glucose inhibited division protein C K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74] D Mfl357 GTP-binding protein, endoglucanase/xylanase K03978 engB; GTP-binding protein D Mfl066 unknown protein K09762 whiA; cell division protein WhiA C 03400 DNA repair and recombination proteins [BR:mfl03400] D Mfl243 uracil-DNA glycosylase 1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D Mfl277 DNA-3-methyladenine glycosidase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D Mfl581 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D Mfl333 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D Mfl160 DNA ligase, polydeoxyribonucleotide synthase NAD+ K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Mfl582 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Mfl059 repair endonuclease subunit A K03701 uvrA; excinuclease ABC subunit A D Mfl058 repair endonuclease subunit B K03702 uvrB; excinuclease ABC subunit B D Mfl101 repair endonuclease subunit C K03703 uvrC; excinuclease ABC subunit C D Mfl566 repair endonuclease ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Mfl598 DNA-directed RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D Mfl597 DNA-directed RNA polymerase beta subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D Mfl150 DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D Mfl649 RNA polymerase subunit delta K03048 rpoE; DNA-directed RNA polymerase subunit delta D Mfl331 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D Mfl330 unknown protein K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D Mfl583 DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Mfl288 DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D Mfl002 DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Mfl368 unknown protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Mfl675 DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Mfl678 DNA polymerase III gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Mfl081 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Mfl322 exodeoxyribonuclease V K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D Mfl206 recombinase A K03553 recA; recombination protein RecA D Mfl421 holliday junction DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA D Mfl420 holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D Mfl462 putative multidrug ABC transporter ATP-binding component K03546 sbcC; DNA repair protein SbcC/Rad50 D Mfl267 DNA repair/recombination protein K03584 recO; DNA repair protein RecO (recombination protein O) D Mfl677 recombination protein K06187 recR; recombination protein RecR D Mfl203 recombination protein U K03700 recU; recombination protein U D Mfl007 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D Mfl006 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D Mfl654 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D Mfl201 predicted histone-like DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D Mfl328 DNA polymerase IV (PolIV) K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D Mfl528 ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Mfl530 ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D Mfl488 exopolyphosphatase-like K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] D Mfl636 exopolyphosphatase-like K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] C 03029 Mitochondrial biogenesis [BR:mfl03029] D Mfl295 translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2 D Mfl188 translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D Mfl560 translation elongation factor Ts K02357 tsf; elongation factor Ts D Mfl621 translation elongation factor Tu K02358 tuf; elongation factor Tu D Mfl622 translation elongation factor G K02355 fusA; elongation factor G D Mfl266 GTP-binding protein, cell cycle control K03595 era; GTPase D Mfl587 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Mfl490 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Mfl365 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Mfl268 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Mfl554 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Mfl162 Glu-tRNA amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D Mfl163 Glu-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D Mfl161 Glu-tRNA amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D Mfl081 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Mfl415 hsp70 chaperone K04043 dnaK; molecular chaperone DnaK D Mfl416 hsp70 cofactor K03687 GRPE; molecular chaperone GrpE D Mfl414 heat shock protein chaperone K03686 dnaJ; molecular chaperone DnaJ D Mfl681 predicted inner membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:mfl02000] D Mfl168 unknown substrate ABC transporter permease component K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial D Mfl422 probable multidrug ABC transporter K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial D Mfl423 probable multidrug ABC transporter K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial D Mfl534 multidrug/protein/lipid ABC transporter ATP-binding component K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial D Mfl533 probable multidrug ABC transporter K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial D Mfl509 spermidine/putrescine ABC transporter permease component K11070 potC; spermidine/putrescine transport system permease protein D Mfl510 spermidine/putrescine ABC transporter permease component K11071 potB; spermidine/putrescine transport system permease protein D Mfl511 spermidine/putrescine ABC transporter ATP-binding component K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11] D Mfl024 sn-glycerol-3-phosphate ABC transporter ATP-binding component K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D Mfl669 xylose ABC transporter periplasmic binding component K07335 bmpA; basic membrane protein A and related proteins D Mfl667 ribose ABC transporter permease component K23535 nupB; general nucleoside transport system permease protein D Mfl666 ribose ABC transporter permease component K23536 nupC; general nucleoside transport system permease protein D Mfl668 ribose ABC transporter ATP-binding component K23537 nupA; general nucleoside transport system ATP-binding protein D Mfl025 sn-glycerol-3-phosphate ABC transporter permease component K02025 ABC.MS.P; multiple sugar transport system permease protein D Mfl026 sn-glycerol-3-phosphate ABC transporter permease component K02026 ABC.MS.P1; multiple sugar transport system permease protein D Mfl233 phosphate ABC transporter transmembrane component K02040 pstS; phosphate transport system substrate-binding protein D Mfl234 phosphate ABC transporter permease component K02037 pstC; phosphate transport system permease protein D Mfl235 phosphate ABC transporter ATP-binding component K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Mfl573 unknown lipoprotein K02044 phnD; phosphonate transport system substrate-binding protein D Mfl571 phosphonate ABC transporter permease component K02042 phnE; phosphonate transport system permease protein D Mfl572 phosphonate ABC transporter ATP-binding component K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2] D Mfl098 oligopeptide ABC transporter periplasmic binding component K15580 oppA; oligopeptide transport system substrate-binding protein D Mfl094 oligopeptide ABC transporter permease component K15581 oppB; oligopeptide transport system permease protein D Mfl095 oligopeptide ABC transporter permease component K15582 oppC; oligopeptide transport system permease protein D Mfl096 oligopeptide ABC transporter ATP-binding component K15583 oppD; oligopeptide transport system ATP-binding protein D Mfl097 oligopeptide ABC transporter ATP-binding component K10823 oppF; oligopeptide transport system ATP-binding protein D Mfl154 cobalt ABC transporter permease component K16785 ecfT; energy-coupling factor transport system permease protein D Mfl152 cobalt ABC transporter ATP-binding component K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D Mfl153 cobalt ABC transporter ATP-binding component K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D Mfl256 unknown transmembrane protein K25147 berB; beta-exotoxin I transport system permease protein D Mfl255 multidrug ABC transporter ATP-binding component K25148 berA; beta-exotoxin I transport system ATP-binding protein D Mfl184 putative amino acid ABC transporter permease component K01992 ABC-2.P; ABC-2 type transport system permease protein D Mfl645 putative multidrug ABC transporter permease component K01992 ABC-2.P; ABC-2 type transport system permease protein D Mfl518 unknown transmembrane protein K01992 ABC-2.P; ABC-2 type transport system permease protein D Mfl460 unknown lipoprotein K01992 ABC-2.P; ABC-2 type transport system permease protein D Mfl646 putative multidrug ABC transporter ATP-binding component K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Mfl182 putative amino acid ABC transporter ATP-binding component K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Mfl450 putative multidrug ABC transporter ATP-binding component K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Mfl401 unknown substrate ABC transporter permease component K02004 ABC.CD.P; putative ABC transport system permease protein D Mfl156 unknown substrate ABC transporter permease K02004 ABC.CD.P; putative ABC transport system permease protein D Mfl159 unknown substrate ABC transporter permease component K02004 ABC.CD.P; putative ABC transport system permease protein D Mfl019 glutamine ABC transporter K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Mfl519 phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] D Mfl565 phosphotransferase system phosphohistidine-containing protein K02784 ptsH; phosphocarrier protein HPr D Mfl187 glucose-specific PTS system IIA component K02777 crr; sugar PTS system EIIA component [EC:2.7.1.-] D Mfl214 glucose-specific PTS system IIABC component K02779 ptsG; glucose PTS system EIICB or EIICBA component [EC:2.7.1.199] D Mfl516 sucrose PTS system IIBC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D Mfl619 unknown substrate PTS system IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D Mfl312 beta-glucoside PTS system IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D Mfl318 beta-glucoside PTS system IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D Mfl008 beta-glucoside PTS system IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D Mfl033 beta-glucoside PTS system IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D Mfl527 sucrose PTS system IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D Mfl426 trehalose/sucrose/beta-glucoside PTS system IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D Mfl431 trehalose/sucrose/beta-glucoside PTS system IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D Mfl500 trehalose PTS system IIABC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D Mfl181 fructose-specific PTS system IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D Mfl643 unknown substrate putative PTS system IIC component K03475 ulaA; ascorbate PTS system EIIC component D Mfl186 formate/nitrate transporter K06212 focA; formate transporter D Mfl217 Mg/Co/Ni transporter K06213 mgtE; magnesium transporter D Mfl605 putative amino acid/amine (Lysine) APC transporter K19540 frlA; fructoselysine transporter D Mfl166 K+, Na+ uptake protein bound cytoplasmic subunit K03498 trkH; trk/ktr system potassium uptake protein D Mfl165 K+, Na+ uptake protein integral membrane subunit K03499 trkA; trk/ktr system potassium uptake protein D Mfl658 xanthine/uracil permease K02824 uraA; uracil permease D Mfl413 putative xanthine/uracil permease K06901 pbuG; adenine/guanine/hypoxanthine permease D Mfl378 putative malate permease K24180 mleP; malate permease and related proteins D Mfl576 putative permease K23675 fmnP; riboflavin transporter D Mfl086 Glu-tRNA amidotransferase subunit C K23675 fmnP; riboflavin transporter D Mfl035 unknown transporter protein K16789 thiT; thiamine transporter C 02044 Secretion system [BR:mfl02044] D Mfl354 putative chromosome segregation ATPase K08086 fimV; pilus assembly protein FimV D Mfl385 deoxycytidylate deaminase K01493 comEB; dCMP deaminase [EC:3.5.4.12] D Mfl369 DNA uptake protein K02238 comEC; competence protein ComEC D Mfl057 preprotein translocase K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Mfl275 protein-export membrane protein K12257 secDF; SecD/SecF fusion protein D Mfl090 preprotein translocase K03073 secE; preprotein translocase subunit SecE D Mfl068 preprotein translocase K03075 secG; preprotein translocase subunit SecG D Mfl142 preprotein translocase K03076 secY; preprotein translocase subunit SecY D Mfl479 signal recognition particle (signal binding protein) K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Mfl237 signal recognition particle, cell division protein GTPase K03110 ftsY; fused signal recognition particle receptor D Mfl681 predicted inner membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase C 02042 Bacterial toxins [BR:mfl02042] C 02022 Two-component system C 02035 Bacterial motility proteins C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:mfl04812] D Mfl003 actin-like protein K03569 mreB; rod shape-determining protein MreB and related proteins D Mfl392 cell division initiation protein K03531 ftsZ; cell division protein FtsZ C 04147 Exosome [BR:mfl04147] D Mfl468 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Mfl578 glyceraldehyde 3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D Mfl577 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Mfl175 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Mfl415 hsp70 chaperone K04043 dnaK; molecular chaperone DnaK D Mfl254 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Mfl343 IMP dehydrogenase (Inosine-5'-monophosphate dehydrogenase) K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D Mfl621 translation elongation factor Tu K02358 tuf; elongation factor Tu D Mfl245 putative nucleotidyl hydrolase/transferase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D Mfl596 L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D Mfl144 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D Mfl276 adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D Mfl042 dihydrolipate dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Mfl504 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 02048 Prokaryotic defense system [BR:mfl02048] D Mfl308 modification methylase Sau3AI (GATC cytosine-specific methyltransferase) K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mfl304 deoxycytosine methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mfl392 cell division initiation protein K03531 ftsZ; cell division protein FtsZ D Mfl003 actin-like protein K03569 mreB; rod shape-determining protein MreB and related proteins D Mfl310 DNA topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D Mfl309 DNA topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D Mfl651 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules [BR:mfl04090] C 01504 Antimicrobial resistance genes C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:mfl03100] D Mflt023 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Mflt027 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Mflt025 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Mflt02 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Mflt018 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Mflt026 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Mflt012 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Mflt03 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Mflt09 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Mflt01 tRNA-His K14226 tRNA-His; tRNA His D Mflt016 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Mflt08 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Mflt010 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Mflt07 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Mflt06 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Mflt011 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Mflt022 tRNA-Met K14230 tRNA-Met; tRNA Met D Mflt021 tRNA-Met K14230 tRNA-Met; tRNA Met D Mflt019 tRNA-Met K14230 tRNA-Met; tRNA Met D Mflt017 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D Mflt024 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Mflt020 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Mflt015 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Mflt05 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Mflt014 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Mflt028 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D Mflt013 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D Mflt04 tRNA-Val K14237 tRNA-Val; tRNA Val D Mflt029 tRNA-Sec K14238 tRNA-Sec; tRNA Sec # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D Mfl052 acyl carrier protein phosphodiesterase K01118 acpD; FMN-dependent NADH-azoreductase [EC:1.7.1.17] D Mfl046 acyl carrier protein phosphodiesterase K01118 acpD; FMN-dependent NADH-azoreductase [EC:1.7.1.17] D Mfl050 peptide methionine sulfoxide reductase K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] D Mfl117 organic hydroperoxide resistance protein K04063 osmC; lipoyl-dependent peroxiredoxin [EC:1.11.1.28] D Mfl065 prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145] D Mfl063 prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145] D Mfl229 dihydroxyacetone kinase K07030 fakA; fatty acid kinase [EC:2.7.2.18] D Mfl062 serine/threonine protein kinase K06023 hprK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-] D Mfl047 Mg2+ dependent DNAse K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D Mfl048 Mg2+ dependent DNAse K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D Mfl004 predicted nucleotidyltransferase, primase K05985 rnmV; ribonuclease M5 [EC:3.1.26.8] D Mfl317 alpha glucosidase/alpha-xylosidase K01811 xylS; alpha-D-xyloside xylohydrolase [EC:3.2.1.177] D Mfl569 polypeptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D Mfl558 putative chitin deacetylase K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104] D Mfl356 Mg2+ transport ATPase K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10] D Mfl496 Mg2+ transport ATPase K01531 mgtA; P-type Mg2+ transporter [EC:7.2.2.14] C 99981 Carbohydrate metabolism C 99982 Energy metabolism D Mfl249 nifU protein homolog K04488 iscU; nitrogen fixation protein NifU and related proteins C 99983 Lipid metabolism D Mfl590 putative fatty acid binding/lipid transport protein K25232 fakB; fatty acid kinase fatty acid binding subunit C 99984 Nucleotide metabolism D Mfl529 ribonucleotide reductase K03647 nrdI; protein involved in ribonucleotide reduction C 99985 Amino acid metabolism C 99986 Glycan metabolism C 99987 Cofactor metabolism C 99988 Secondary metabolism C 99999 Others B B 09192 Unclassified: genetic information processing C 99973 Transcription C 99974 Translation D Mfl341 polyribonucleotide nucleotidyltransferase/predicted RNA-binding protein containing ribosomal protein S1 domain K07570 GSP13; general stress protein 13 C 99975 Protein processing D Mfl405 trigger factor, prolyl isomerase K03545 tig; trigger factor D Mfl210 tmRNA/ssrA-binding protein K03664 smpB; SsrA-binding protein C 99976 Replication and repair D Mfl475 ribonuclease HI K06993 K06993; ribonuclease H-related protein D Mfl535 DNA processing/uptake protein K04096 smf; DNA processing protein D Mfl403 putative helicase subunit of Holliday junction resolvase K07478 ycaJ; putative ATPase C 99979 Viral proteins C 99998 Others D Mfl104 rhodanese-related sulfurtransferase, phage shock protein K03972 pspE; phage shock protein E B B 09193 Unclassified: signaling and cellular processes C 99977 Transport C 99978 Cell growth C 99993 Cell motility C 99995 Signaling proteins D Mfl469 GTP-binding membrane protein, elongation factor K06207 typA; GTP-binding protein C 99992 Structural proteins C 99994 Others D Mfl236 phosphate transport system transcriptional regulator K02039 phoU; phosphate transport system protein B B 09194 Poorly characterized C 99996 General function prediction only D Mfl607 predicted acyltransferase K02348 elaA; ElaA protein D Mfl589 similar to phenylalanyl-tRNA synthetase, beta subunit K06878 K06878; tRNA-binding protein D Mfl604 putative ABC transporter K01421 yhgE; putative membrane protein C 99997 Function unknown D Mfl650 predicted HD phosphohydrolase K06885 K06885; uncharacterized protein D Mfl390 predicted hydrolase K06889 K06889; uncharacterized protein D Mfl606 putative hydrolase K06889 K06889; uncharacterized protein D Mfl482 putative lipase K06889 K06889; uncharacterized protein D Mfl315 lysophospholipase K06889 K06889; uncharacterized protein D Mfl652 putative sodium-glutamate symporter K06956 K06956; uncharacterized protein D Mfl298 ATP/GTP binding protein K09384 K09384; uncharacterized protein D Mfl238 gene regulatory DNA-binding protein K09787 K09787; uncharacterized protein D Mfl348 unknown transmembrane protein K09976 K09976; uncharacterized protein D Mfl440 predicted ribosomal protein K07584 ysxB; uncharacterized protein D Mfl293 unknown protein K07742 ylxR; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: May 15, 2024