+D GENES KO
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KEGG Orthology (KO) - Methanopyrus kandleri
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A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:mka00010]
D MK0954 Uncharacterized conserved protein K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D MK1409 fbaB; Fructose-1,6-bisphosphate aldolase of the DhnA family K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D MK1664 tpiA; Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D MK0618 gapA; Glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D MK1662 pgk; 3-phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D MK1193 Predicted phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D MK1647 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D MK0252 ppsA; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D MK0849 lpd; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D MK0082 porA_1; Pyruvate:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D MK0083 porB_1; Pyruvate:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D MK0080 porG_1; Pyruvate:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D MK0081 porD; Pyruvate:ferredoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D MK0728 porA_2; Pyruvate:ferredoxin oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D MK0729 porB_2; Pyruvate:ferredoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D MK1246 Acyl-CoA synthetase (NDP forming) K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13]
D MK1023 Acyl-CoA synthetase (NDP forming) K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13]
D MK0920 cpsG_2; Phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
C 00020 Citrate cycle (TCA cycle) [PATH:mka00020]
D MK0849 lpd; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D MK0728 porA_2; Pyruvate:ferredoxin oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D MK0729 porB_2; Pyruvate:ferredoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D MK0730 porG_2; Pyruvate:ferredoxin oxidoreductase, gamma subunit K00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]
D MK0727 Ferredoxin K00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]
D MK0732 sucD; Succinyl-CoA synthetase alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D MK0731 sucC; Succinyl-CoA synthetase beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D MK0085 ttdA; Fumarate hydratase class I, N-terminal domain K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D MK0086 fumA; Fumarate hydratase class I, C-terminal domain K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D MK1069 mdh; NADPH-dependent L-malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D MK0082 porA_1; Pyruvate:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D MK0083 porB_1; Pyruvate:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D MK0080 porG_1; Pyruvate:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D MK0081 porD; Pyruvate:ferredoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
C 00030 Pentose phosphate pathway [PATH:mka00030]
D MK1665 rpiA; Ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D MK1449 menG; Demethylmenaquinone methyltransferase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43]
D MK0153 sgbH; 3-hexulose-6-phosphate synthase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43]
D MK1663 Predicted sugar phosphate isomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
D MK0920 cpsG_2; Phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D MK1667 prsA; Phosphoribosylpyrophosphate synthetase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D MK0954 Uncharacterized conserved protein K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D MK1409 fbaB; Fructose-1,6-bisphosphate aldolase of the DhnA family K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
C 00040 Pentose and glucuronate interconversions
D MK1585 Predicted epimerase related to ribulose-5-phosphate 4-epimerase K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]
C 00051 Fructose and mannose metabolism [PATH:mka00051]
D MK0920 cpsG_2; Phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D MK0917 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis; translation initiation factor eIF2B subunit K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D MK1585 Predicted epimerase related to ribulose-5-phosphate 4-epimerase K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]
D MK0954 Uncharacterized conserved protein K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D MK1409 fbaB; Fructose-1,6-bisphosphate aldolase of the DhnA family K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D MK1664 tpiA; Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 00052 Galactose metabolism [PATH:mka00052]
D MK0724 Nucleoside-diphosphate-sugar epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D MK0920 cpsG_2; Phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
C 00053 Ascorbate and aldarate metabolism
C 00500 Starch and sucrose metabolism
D MK0920 cpsG_2; Phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:mka00520]
D MK0127 glmS; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domain K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D MK0918 agaS; Predicted phosphosugar isomerase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D MK0893 cpsG_1; Phosphomannomutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D MK0892 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis; translation initiation factor eIF2B subunit K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D MK0840 Predicted molecular chaperone distantly related to HSP70-fold metalloproteases K09001 anmK; anhydro-N-acetylmuramic acid kinase [EC:2.7.1.170]
D MK0920 cpsG_2; Phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D MK0724 Nucleoside-diphosphate-sugar epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D MK0917 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis; translation initiation factor eIF2B subunit K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D MK0156 Predicted pyridoxal-phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis K13010 per; perosamine synthetase [EC:2.6.1.102]
C 00620 Pyruvate metabolism [PATH:mka00620]
D MK0082 porA_1; Pyruvate:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D MK0083 porB_1; Pyruvate:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D MK0080 porG_1; Pyruvate:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D MK0081 porD; Pyruvate:ferredoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D MK0728 porA_2; Pyruvate:ferredoxin oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D MK0729 porB_2; Pyruvate:ferredoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D MK0849 lpd; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D MK1246 Acyl-CoA synthetase (NDP forming) K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13]
D MK1023 Acyl-CoA synthetase (NDP forming) K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13]
D MK1634 Zn-dependent hydrolase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D MK1069 mdh; NADPH-dependent L-malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D MK0085 ttdA; Fumarate hydratase class I, N-terminal domain K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D MK0086 fumA; Fumarate hydratase class I, C-terminal domain K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D MK0190 Uncharacterized protein conserved in archaea K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D MK0252 ppsA; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D MK1378 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D MK0391 Isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D MK1209 leuA; Isopropylmalate synthase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:mka00630]
D MK1069 mdh; NADPH-dependent L-malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D MK1378 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D MK0203 Predicted hydrolase of the HAD superfamily K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18]
D MK0338 glnA; Glutamine synthase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D MK0122 glyA; Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D MK0849 lpd; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00640 Propanoate metabolism [PATH:mka00640]
D MK1246 Acyl-CoA synthetase (NDP forming) K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13]
D MK1023 Acyl-CoA synthetase (NDP forming) K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13]
D MK0849 lpd; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D MK0082 porA_1; Pyruvate:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D MK0083 porB_1; Pyruvate:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D MK0080 porG_1; Pyruvate:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D MK0081 porD; Pyruvate:ferredoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D MK0731 sucC; Succinyl-CoA synthetase beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D MK0732 sucD; Succinyl-CoA synthetase alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
C 00650 Butanoate metabolism [PATH:mka00650]
D MK1378 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D MK0082 porA_1; Pyruvate:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D MK0083 porB_1; Pyruvate:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D MK0080 porG_1; Pyruvate:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D MK0081 porD; Pyruvate:ferredoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D MK0728 porA_2; Pyruvate:ferredoxin oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D MK0729 porB_2; Pyruvate:ferredoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D MK1379 pksG; 3-hydroxy-3-methylglutaryl CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D MK0531 ilvB_2; Acetolactate synthase, large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D MK1236 Acetolactate synthase large subunit homolog K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D MK0545 ilvH; Acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
C 00660 C5-Branched dibasic acid metabolism [PATH:mka00660]
D MK0531 ilvB_2; Acetolactate synthase, large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D MK1236 Acetolactate synthase large subunit homolog K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D MK0545 ilvH; Acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D MK0731 sucC; Succinyl-CoA synthetase beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D MK0732 sucD; Succinyl-CoA synthetase alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D MK0275 Isopropylmalate/homocitrate/citramalate synthase homolog K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21]
D MK1440 leuC_1; 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D MK0781 leuD_1; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D MK0782 leuB_1; Isocitrate/isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
C 00562 Inositol phosphate metabolism [PATH:mka00562]
D MK0741 suhB; Archaea-specific fructose-1,6-bisphosphatase fused to predicted pyrophosphatase of the PRA-PH family K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D MK1664 tpiA; Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:mka00190]
D MK1017 ntpA; Archaeal/vacuolar-type H+-ATPase subunit A K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
D MK1673 ntpB; Archaeal/vacuolar-type H+-ATPase subunit B, contains an intein K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B
D MK1015 ntpC; Archaeal/vacuolar-type H+-ATPase subunit C K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C
D MK1674 ntpD; Archaeal/vacuolar-type H+-ATPase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D
D MK1014 ntpE; Archaeal/vacuolar-type H+-ATPase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E
D MK1016 ntpF; Archaeal/vacuolar-type H+-ATPase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F
D MK1012 ntpI; Archaeal/vacuolar-type H+-ATPase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I
D MK1013 ntpK; Archaeal/vacuolar-type H+-ATPase subunit K K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K
D MK1450 ppa; Inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation in photosynthetic organisms
C 00720 Carbon fixation pathways in prokaryotes [PATH:mka00720]
D MK0082 porA_1; Pyruvate:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D MK0083 porB_1; Pyruvate:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D MK0080 porG_1; Pyruvate:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D MK0081 porD; Pyruvate:ferredoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D MK0252 ppsA; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D MK0190 Uncharacterized protein conserved in archaea K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D MK1069 mdh; NADPH-dependent L-malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D MK0085 ttdA; Fumarate hydratase class I, N-terminal domain K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D MK0086 fumA; Fumarate hydratase class I, C-terminal domain K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D MK0828 sdhA; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit K18209 tfrA; fumarate reductase (CoM/CoB) subunit A [EC:1.3.4.1]
D MK0132 frdB_glpC; Succinate dehydrogenase/fumarate reductase Fe-S protein K18210 tfrB; fumarate reductase (CoM/CoB) subunit B [EC:1.3.4.1]
D MK0498 Fe-S oxidoreductase K18210 tfrB; fumarate reductase (CoM/CoB) subunit B [EC:1.3.4.1]
D MK0732 sucD; Succinyl-CoA synthetase alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D MK0731 sucC; Succinyl-CoA synthetase beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D MK1378 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D MK0728 porA_2; Pyruvate:ferredoxin oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D MK0729 porB_2; Pyruvate:ferredoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D MK0730 porG_2; Pyruvate:ferredoxin oxidoreductase, gamma subunit K00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]
D MK0727 Ferredoxin K00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]
D MK0536 carbon monoxide dehydrogenase catalytic subunit K00198 cooS; anaerobic carbon-monoxide dehydrogenase catalytic subunit [EC:1.2.7.4]
D MK0084 Fe-S-cluster-containing hydrogenase component K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit
D MK0723 cdhE; CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) K00197 cdhE; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245]
D MK0722 cdhD; CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein) K00194 cdhD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245]
C 00680 Methane metabolism [PATH:mka00680]
D MK0321 Selenocysteine-containing anaerobic dehydrogenase K22516 fdhA; formate dehydrogenase (coenzyme F420) alpha subunit [EC:1.17.98.3 1.8.98.6]
D MK0322 Coenzyme F420-reducing hydrogenase, beta subunit K00125 fdhB; formate dehydrogenase (coenzyme F420) beta subunit [EC:1.17.98.3 1.8.98.6]
D MK0719 cdhA_1; CO dehydrogenase/acetyl-CoA synthase alpha subunit K00192 cdhA; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit alpha [EC:1.2.7.4]
D MK0717 cdhA_1; CO dehydrogenase/acetyl-CoA synthase alpha subunit K00192 cdhA; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit alpha [EC:1.2.7.4]
D MK0718 cdhB; CO dehydrogenase/acetyl-CoA synthase epsilon subunit K00195 cdhB; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit epsilon
D MK0720 cdhC; CO dehydrogenase/acetyl-CoA synthase beta subunit K00193 cdhC; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit beta [EC:2.3.1.169]
D MK0723 cdhE; CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) K00197 cdhE; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245]
D MK0722 cdhD; CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein) K00194 cdhD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245]
D MK0536 carbon monoxide dehydrogenase catalytic subunit K00198 cooS; anaerobic carbon-monoxide dehydrogenase catalytic subunit [EC:1.2.7.4]
D MK0084 Fe-S-cluster-containing hydrogenase component K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit
D MK0122 glyA; Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D MK1647 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D MK0190 Uncharacterized protein conserved in archaea K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D MK1069 mdh; NADPH-dependent L-malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D MK0954 Uncharacterized conserved protein K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D MK1409 fbaB; Fructose-1,6-bisphosphate aldolase of the DhnA family K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D MK1663 Predicted sugar phosphate isomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
D MK1449 menG; Demethylmenaquinone methyltransferase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43]
D MK0153 sgbH; 3-hexulose-6-phosphate synthase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43]
D MK1063 gltB_2; Glutamate synthase subunit 1 K22081 mgsA; methylamine---glutamate N-methyltransferase subunit A [EC:2.1.1.21]
D MK1064 gltB_3; Glutamate synthase subunit 3 K22082 mgsB; methylamine---glutamate N-methyltransferase subunit B [EC:2.1.1.21]
D MK0550 gltB_1; Glutamate synthase subunit 2 K22083 mgsC; methylamine---glutamate N-methyltransferase subunit C [EC:2.1.1.21]
D MK1529 fwdA; Formylmethanofuran dehydrogenase subunit A K00200 fwdA; formylmethanofuran dehydrogenase subunit A [EC:1.2.7.12]
D MK0259 fwdB_1; Formylmethanofuran dehydrogenase subunit B K00201 fwdB; formylmethanofuran dehydrogenase subunit B [EC:1.2.7.12]
D MK1527 fwdB_2; Formylmethanofuran dehydrogenase subunit B, selenocysteine containing K00201 fwdB; formylmethanofuran dehydrogenase subunit B [EC:1.2.7.12]
D MK1530 fwdC; Formylmethanofuran dehydrogenase subunit C K00202 fwdC; formylmethanofuran dehydrogenase subunit C [EC:1.2.7.12]
D MK1526 fwdD; Formylmethanofuran dehydrogenase subunit D K00203 fwdD; formylmethanofuran dehydrogenase subunit D [EC:1.2.7.12]
D MK1625 Ferredoxin fused to cHTH-type DNA-binding domain K00204 fwdH; 4Fe-4S ferredoxin
D MK0307 fwdF_1; Probable formylmethanofuran dehydrogenase subunit F, ferredoxin containing K00205 fwdF; 4Fe-4S ferredoxin
D MK0323 fwd_F2; Probable formylmethanofuran dehydrogenase subunit F, ferredoxin containing K00205 fwdF; 4Fe-4S ferredoxin
D MK1525 fwdG; Ferredoxin K11260 fwdG; 4Fe-4S ferredoxin
D MK0116 ftr_1; Formylmethanofuran:tetrahydromethanopterin formyltransferase K00672 ftr; formylmethanofuran--tetrahydromethanopterin N-formyltransferase [EC:2.3.1.101]
D MK0816 ftr_2; Formylmethanofuran:tetrahydromethanopterin formyltransferase K00672 ftr; formylmethanofuran--tetrahydromethanopterin N-formyltransferase [EC:2.3.1.101]
D MK0625 mch; Methenyltetrahydromethanopterin cyclohydrolase K01499 mch; methenyltetrahydromethanopterin cyclohydrolase [EC:3.5.4.27]
D MK0011 mtd; F420 dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase K00319 mtd; methylenetetrahydromethanopterin dehydrogenase [EC:1.5.98.1]
D MK0931 Coenzyme F420-reducing hydrogenase, alpha subunit K00440 frhA; coenzyme F420 hydrogenase subunit alpha [EC:1.12.98.1]
D MK1202 hyaB; Ni,Fe-hydrogenase I large subunit K00440 frhA; coenzyme F420 hydrogenase subunit alpha [EC:1.12.98.1]
D MK0537 Coenzyme F420-reducing hydrogenase, alpha subunit K00440 frhA; coenzyme F420 hydrogenase subunit alpha [EC:1.12.98.1]
D MK0539 Coenzyme F420-reducing hydrogenase, beta subunit K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1]
D MK0929 Coenzyme F420-reducing hydrogenase, beta subunit K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1]
D MK1624 hyaD_2; Ni,Fe-hydrogenase maturation factor K00442 frhD; coenzyme F420 hydrogenase subunit delta
D MK0538 Coenzyme F420-reducing hydrogenase, gamma subunit K00443 frhG; coenzyme F420 hydrogenase subunit gamma [EC:1.12.98.1]
D MK0930 Coenzyme F420-reducing hydrogenase, gamma subunit K00443 frhG; coenzyme F420 hydrogenase subunit gamma [EC:1.12.98.1]
D MK0013 hmd; N5,N10-methylenetetrahydromethanopterin dehydrogenase (H2-forming) K13942 hmd; 5,10-methenyltetrahydromethanopterin hydrogenase [EC:1.12.98.2]
D MK1275 Uncharacterized protein conserved in archaea K10713 fae; 5,6,7,8-tetrahydromethanopterin hydro-lyase [EC:4.2.1.147]
D MK0524 mer; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase K00320 mer; 5,10-methylenetetrahydromethanopterin reductase [EC:1.5.98.2]
D MK0660 mtrA; N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit A K00577 mtrA; tetrahydromethanopterin S-methyltransferase subunit A [EC:7.2.1.4]
D MK0659 mtrB; N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit B K00578 mtrB; tetrahydromethanopterin S-methyltransferase subunit B [EC:7.2.1.4]
D MK0658 mtrC; N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit C K00579 mtrC; tetrahydromethanopterin S-methyltransferase subunit C [EC:7.2.1.4]
D MK0657 mtrD; N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit D K00580 mtrD; tetrahydromethanopterin S-methyltransferase subunit D [EC:7.2.1.4]
D MK0656 mtrE; N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit E K00581 mtrE; tetrahydromethanopterin S-methyltransferase subunit E [EC:7.2.1.4]
D MK1485 mtrF; N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit F K00582 mtrF; tetrahydromethanopterin S-methyltransferase subunit F [EC:7.2.1.4]
D MK0661 mtrG; N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit G K00583 mtrG; tetrahydromethanopterin S-methyltransferase subunit G [EC:7.2.1.4]
D MK0662 mtrH; N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit H K00584 mtrH; tetrahydromethanopterin S-methyltransferase subunit H [EC:7.2.1.4]
D MK0655 mcrA; Methyl coenzyme M reductase, alpha subunit K00399 mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
D MK1189 ATPase subunit of an ABC-type transport system, contains a duplicated ATPase domain K00400 K00400; methyl coenzyme M reductase system, component A2
D MK1433 ATPase subunit of an ABC-type transport system, contain duplicated ATPase K00400 K00400; methyl coenzyme M reductase system, component A2
D MK0651 mcrB; Methyl coenzyme M reductase, beta subunit K00401 mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1]
D MK0654 mcrG; Methyl coenzyme M reductase, gamma subunit K00402 mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1]
D MK0653 mcrC; Methyl coenzyme M reductase, subunit C K03421 mcrC; methyl-coenzyme M reductase subunit C
D MK0652 mcrD; Methyl coenzyme M reductase, subunit D K03422 mcrD; methyl-coenzyme M reductase subunit D
D MK0249 hdrA_1; Heterodisulfide reductase, subunit A K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D MK0265 hdrA_2; Heterodisulfide reductase, subunit A, polyferredoxin K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D MK0572 hdrB; Heterodisulfide reductase, subunit B K03389 hdrB2; heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D MK0573 hdrC; Heterodisulfide reductase, subunit C K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D MK0268 flpD_1; Coenzyme F420-reducing hydrogenase, delta subunit K14127 mvhD; F420-non-reducing hydrogenase iron-sulfur subunit [EC:1.12.99.- 1.8.98.5 1.8.98.6]
D MK0627 flpD_2; Coenzyme F420-reducing hydrogenase, delta subunit K14127 mvhD; F420-non-reducing hydrogenase iron-sulfur subunit [EC:1.12.99.- 1.8.98.5 1.8.98.6]
D MK0266 Coenzyme F420-reducing hydrogenase, alpha subunit K14126 mvhA; F420-non-reducing hydrogenase large subunit [EC:1.12.99.- 1.8.98.5]
D MK0178 Coenzyme F420-reducing hydrogenase, alpha subunit K14126 mvhA; F420-non-reducing hydrogenase large subunit [EC:1.12.99.- 1.8.98.5]
D MK0267 Coenzyme F420-reducing hydrogenase, gamma subunit K14128 mvhG; F420-non-reducing hydrogenase small subunit [EC:1.12.99.- 1.8.98.5]
D MK0179 Coenzyme F420-reducing hydrogenase, gamma subunit K14128 mvhG; F420-non-reducing hydrogenase small subunit [EC:1.12.99.- 1.8.98.5]
D MK0082 porA_1; Pyruvate:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D MK0083 porB_1; Pyruvate:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D MK0080 porG_1; Pyruvate:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D MK0081 porD; Pyruvate:ferredoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D MK0252 ppsA; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D MK1193 Predicted phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D MK0297 Predicted dehydrogenase related to phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D MK0319 Predicted dehydrogenase related to phosphoglycerate dehydrogenase, a fragment K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D MK0320 serA; Predicted dehydrogenase related to phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D MK0121 serB; Phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D MK0394 comA; (2R)-phospho-3-sulfolactate synthase K08097 comA; phosphosulfolactate synthase [EC:4.4.1.19]
D MK0138 comB; 2-phosphosulfolactate phosphatase K05979 comB; 2-phosphosulfolactate phosphatase [EC:3.1.3.71]
D MK0392 comC; L-sulfolactate dehydrogenase K05884 comC; L-2-hydroxycarboxylate dehydrogenase (NAD+) [EC:1.1.1.337]
D MK0395 comD; Sulfopyruvate decarboxylase, alpha subunit K06034 comD; sulfopyruvate decarboxylase subunit alpha [EC:4.1.1.79]
D MK0393 comE; Sulfopyruvate decarboxylase, beta subunit K13039 comE; sulfopyruvate decarboxylase subunit beta [EC:4.1.1.79]
D MK0897 thiH_1; Predicted enzyme related to thiamine biosynthesis enzyme ThiH K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147]
D MK0898 thiH_2; Predicted enzyme related to thiamine biosynthesis enzyme ThiH K11780 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase [EC:4.3.1.32]
D MK0587 Uncharacterized conserved protein K14941 cofC; 2-phospho-L-lactate/phosphoenolpyruvate guanylyltransferase [EC:2.7.7.68 2.7.7.105]
D MK1489 Uncharacterized conserved protein K11212 cofD; LPPG:FO 2-phospho-L-lactate transferase [EC:2.7.8.28]
D MK0971 Uncharacterized conserved protein K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34]
D MK1209 leuA; Isopropylmalate synthase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
D MK1208 leuC_2; 3-isopropylmalate dehydratase large subunit K16792 aksD; methanogen homoaconitase large subunit [EC:4.2.1.114]
D MK1206 leuD_2; 3-isopropylmalate dehydratase small subunit K16793 aksE; methanogen homoaconitase small subunit [EC:4.2.1.114]
D MK1215 leuB_2; Isopropylmalate dehydrogenase K10978 aksF; methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-]
D MK1500 Pyridoxal-phosphate-dependent enzyme related to glutamate decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D MK0114 Predicted ATP-utilizing enzymes of the ATP-grasp superfamily K06914 mfnD; tyramine---L-glutamate ligase [EC:6.3.4.24]
D MK1602 Uncharacterized protein conserved in archaea K09733 mfnB; (5-formylfuran-3-yl)methyl phosphate synthase [EC:4.2.3.153]
D MK1498 Archaea-specific kinase related to aspartokinase K07144 mfnE; 5-(aminomethyl)-3-furanmethanol phosphate kinase [EC:2.7.4.31]
D MK0113 Predicted sugar kinase of the RNAseH/HSP70 fold K07072 mfnF; (4-(4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl)furan-2-yl)methanamine synthase [EC:2.5.1.131]
C 00910 Nitrogen metabolism [PATH:mka00910]
D MK1416 nifH; Nitrogenase subunit NifH (ATPase) K02588 nifH; nitrogenase iron protein NifH
D MK0338 glnA; Glutamine synthase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
C 00920 Sulfur metabolism [PATH:mka00920]
D MK0601 Homolog of ABC-type nitrate/sulfonate/taurine/bicarbonate transport systems, periplasmic component K15553 ssuA; sulfonate transport system substrate-binding protein
D MK0602 Homolog of ABC-type nitrate/sulfonate/taurine/bicarbonate transport systems, permease component K15554 ssuC; sulfonate transport system permease protein
D MK0603 Homolog of ABC-type nitrate/sulfonate/taurine/bicarbonate transport systems, ATPase component K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D MK0621 Predicted RNA modification enzyme consisting of a 3-phosphoadenosine 5-phosphosulfate sulfotransferase fused to RNA-binding PUA domain K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:mka00071]
D MK1378 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism
C 00564 Glycerophospholipid metabolism [PATH:mka00564]
D MK0162 psd; Phosphatidylserine decarboxylase K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]
D MK1230 gldA; Glycerol dehydrogenase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
D MK0642 Predicted phosphate-binding enzyme of the TIM-barrel fold K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41]
D MK0953 ubiA; 4-hydroxybenzoate polyprenyltransferase K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42]
D MK1073 cdsA; CDP-diglyceride synthetase K19664 carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67]
D MK0161 pssA; Phosphatidylserine synthase K19665 pssA; archaetidylserine synthase [EC:2.7.8.38]
D MK1645 Predicted dehydrogenase (flavoprotein) K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
D MK1443 Dehydrogenase (flavoprotein) K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:mka00230]
D MK0920 cpsG_2; Phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D MK1667 prsA; Phosphoribosylpyrophosphate synthetase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D MK1649 purF; Glutamine phosphoribosylpyrophosphate amidotransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D MK1071 purD; Phosphoribosylamine-glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D MK0497 purL_2; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
D MK0791 purS; Phosphoribosylformylglycinamidine (FGAM) synthase, PurS subunit K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
D MK0790 purL_1; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase subunit K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D MK1226 purM; Phosphoribosylaminoimidazol (AIR) synthetase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D MK1195 purE; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D MK0792 purC; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D MK1085 purB; Adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D MK0588 Predicted ATP-utilizing enzyme of the ATP-grasp superfamily (probably carboligase) K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23]
D MK0087 purO; IMP cyclohydrolase K11176 purO; IMP cyclohydrolase [EC:3.5.4.10]
D MK0610 Adenine/guanine phosphoribosyltransferase homolog K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D MK0433 surE; Predicted acid phosphatase K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D MK1600 guaB; IMP dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D MK1591 ndk; Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D MK1503 Uncharacterized conserved protein K01529 yjjX; inosine/xanthosine triphosphatase [EC:3.6.1.73]
D MK1594 Xanthosine triphosphate pyrophosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D MK0363 guaA_1; PP-ATPase subunit of GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D MK0551 guaA_2; Glutamine amidotransferase subunit of GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D MK0901 nrdD; Oxygen-sensitive ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D MK0871 cyaB; Adenylate cyclase, class 2 (thermophilic) K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1]
D MK0235 purA; Adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D MK0829 adeC; Adenine deaminase K01486 ade; adenine deaminase [EC:3.5.4.2]
D MK0025 adkA; Archaeal adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D MK1060 Predicted nucleotide kinase related to CMP and AMP kinase K18532 AK6; adenylate kinase [EC:2.7.4.3]
D MK0827 Predicted nucleotide kinase K06928 NTPCR; nucleoside-triphosphatase [EC:3.6.1.15]
C 00240 Pyrimidine metabolism [PATH:mka00240]
D MK0911 carB_2; Carbamoylphosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D MK1666 carB_3; Carbamoylphosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D MK0491 carA; Carbamoylphosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D MK1480 pyrB; Aspartate carbamoyltransferase, catalytic subunit K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D MK1481 pyrI; Aspartate carbamoyltransferase, regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D MK0530 pyrC; Dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3]
D MK0563 pyrD; Dihydroorotate dehydrogenase K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14]
D MK0564 Predicted flavodoxin oxidoreductase related to 2-polyprenylphenol hydroxylase K02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit
D MK1072 pyrE; Orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D MK0735 pyrF; Orotidine-5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D MK0760 pyrH; Uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D MK1591 ndk; Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D MK0205 pyrG; CTP synthase (UTP-ammonia lyase) K01937 pyrG; CTP synthase [EC:6.3.4.2]
D MK0022 cmk; Cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D MK0433 surE; Predicted acid phosphatase K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D MK0901 nrdD; Oxygen-sensitive ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D MK0291 dcd_1; Deoxycytidine deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D MK0101 tmk; Thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D MK1566 dcd_2; Deoxycytidine deaminase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D MK1370 thyA; Thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:mka00250]
D MK0103 asnB; Asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D MK1411 Predicted ornithine cyclodeaminase, mu-crystallin homolog K19244 ala; alanine dehydrogenase [EC:1.4.1.1]
D MK0942 argG; Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D MK0622 argH; Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D MK0235 purA; Adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D MK1085 purB; Adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D MK1480 pyrB; Aspartate carbamoyltransferase, catalytic subunit K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D MK1481 pyrI; Aspartate carbamoyltransferase, regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D MK0338 glnA; Glutamine synthase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D MK0911 carB_2; Carbamoylphosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D MK1666 carB_3; Carbamoylphosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D MK0491 carA; Carbamoylphosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D MK0790 purL_1; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase subunit K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D MK0127 glmS; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domain K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D MK0918 agaS; Predicted phosphosugar isomerase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D MK1649 purF; Glutamine phosphoribosylpyrophosphate amidotransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:mka00260]
D MK0109 lysC; Aspartokinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D MK1389 asd; Aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D MK1554 thrA; Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D MK0333 thrB; Homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39]
D MK0974 thrC; Threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D MK0122 glyA; Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D MK1193 Predicted phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D MK0297 Predicted dehydrogenase related to phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D MK0319 Predicted dehydrogenase related to phosphoglycerate dehydrogenase, a fragment K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D MK0320 serA; Predicted dehydrogenase related to phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D MK0121 serB; Phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D MK0849 lpd; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D MK0403 trpA; Tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D MK0784 trpB; Tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
C 00270 Cysteine and methionine metabolism [PATH:mka00270]
D MK0667 metE; Methionine synthase II (cobalamin-independent) K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D MK1508 Uncharacterized conserved protein K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D MK0961 speE; Spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16]
D MK0366 Predicted metal-dependent hydrolase related to cytosine deaminase K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D MK0021 pnp; Purine nucleoside phosphorylase K19696 mtiP; 5'-methylthioinosine phosphorylase [EC:2.4.2.44]
D MK0335 gcn3; Translation initiation factor eIF-2B alpha subunit K08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23]
D MK1520 dcm; Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D MK0368 S-adenosylhomocysteine hydrolase K01566 E3.13.1.9; S-inosyl-L-homocysteine hydrolase [EC:3.13.1.9]
D MK0109 lysC; Aspartokinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D MK1389 asd; Aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D MK1554 thrA; Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D MK0907 prdicted regulatory protein consisting of a uncharacterized conserved domain fused to a CBS domain K23975 E2.8.1.16; L-aspartate semialdehyde sulfurtransferase [EC:2.8.1.16]
D MK0903 Ferredoxin K23976 K23976; L-aspartate semialdehyde sulfurtransferase ferredoxin
D MK1627 ilvE; Branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D MK1069 mdh; NADPH-dependent L-malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D MK0297 Predicted dehydrogenase related to phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D MK0319 Predicted dehydrogenase related to phosphoglycerate dehydrogenase, a fragment K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D MK0320 serA; Predicted dehydrogenase related to phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
C 00280 Valine, leucine and isoleucine degradation [PATH:mka00280]
D MK1627 ilvE; Branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D MK0849 lpd; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D MK1378 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D MK1379 pksG; 3-hydroxy-3-methylglutaryl CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:mka00290]
D MK0275 Isopropylmalate/homocitrate/citramalate synthase homolog K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21]
D MK1440 leuC_1; 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D MK0781 leuD_1; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D MK0782 leuB_1; Isocitrate/isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
D MK0531 ilvB_2; Acetolactate synthase, large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D MK1236 Acetolactate synthase large subunit homolog K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D MK0545 ilvH; Acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D MK0832 ilvC; Ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D MK1197 ilvD; Dihydroxyacid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D MK1627 ilvE; Branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D MK0391 Isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00300 Lysine biosynthesis [PATH:mka00300]
D MK1554 thrA; Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D MK0109 lysC; Aspartokinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D MK1389 asd; Aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D MK1607 dapA; Dihydrodipicolinate synthase/N-acetylneuraminate lyase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D MK1422 dapB; Dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
D MK0435 dapD; Tetrahydrodipicolinate N-succinyltransferase K00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]
D MK1606 argD; Pyridoxal-phosphate-dependent aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D MK1581 Predicted deacylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D MK0434 dapF; Diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D MK0483 lysA; Diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D MK1209 leuA; Isopropylmalate synthase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
D MK1208 leuC_2; 3-isopropylmalate dehydratase large subunit K16792 aksD; methanogen homoaconitase large subunit [EC:4.2.1.114]
D MK1206 leuD_2; 3-isopropylmalate dehydratase small subunit K16793 aksE; methanogen homoaconitase small subunit [EC:4.2.1.114]
D MK1215 leuB_2; Isopropylmalate dehydrogenase K10978 aksF; methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-]
D MK0752 murE_1; UDP-N-acetylmuramyl tripeptide synthase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
C 00310 Lysine degradation [PATH:mka00310]
D MK0849 lpd; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D MK1378 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00220 Arginine biosynthesis [PATH:mka00220]
D MK1070 argF; Ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D MK0942 argG; Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D MK0622 argH; Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D MK0866 Uncharacterized conserved protein K27542 argZ; arginine dihydrolase [EC:3.5.3.27]
D MK0790 purL_1; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase subunit K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D MK0338 glnA; Glutamine synthase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D MK0865 Predicted kinase related to thiamine pyrophosphokinase K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]
D MK1631 argB; Acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8]
D MK1077 argC; Acetylglutamate semialdehyde dehydrogenase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]
D MK1606 argD; Pyridoxal-phosphate-dependent aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
C 00330 Arginine and proline metabolism [PATH:mka00330]
D MK0183 Uncharacterized protein, putative amidase K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10]
D MK1091 hyuA_1; N-methylhydantoinase A K01473 hyuA; N-methylhydantoinase A [EC:3.5.2.14]
D MK1048 hyuB; N-methylhydantoinase B K01474 hyuB; N-methylhydantoinase B [EC:3.5.2.14]
D MK0740 speA; Pyruvoyl-dependent arginine decarboxylase K02626 pdaD; arginine decarboxylase [EC:4.1.1.19]
D MK0738 speB; Agmatinase K01480 speB; agmatinase [EC:3.5.3.11]
D MK0961 speE; Spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16]
D MK0866 Uncharacterized conserved protein K27542 argZ; arginine dihydrolase [EC:3.5.3.27]
C 00340 Histidine metabolism [PATH:mka00340]
D MK0365 hisG; ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D MK0500 hisI_1; Phosphoribosyl-ATP pyrophosphohydrolase K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]
D MK1537 hisI_2; Phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
D MK0364 hisA; Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D MK1510 hisH; Glutamine amidotransferase K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
D MK0173 hisF; Imidazoleglycerol-phosphate synthase K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D MK0855 hisB; Imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
D MK1426 hisC; Histidinol-phosphate/tyrosine aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D MK0711 hisD; Histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]
C 00350 Tyrosine metabolism [PATH:mka00350]
D MK1426 hisC; Histidinol-phosphate/tyrosine aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D MK1500 Pyridoxal-phosphate-dependent enzyme related to glutamate decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
C 00360 Phenylalanine metabolism
D MK1426 hisC; Histidinol-phosphate/tyrosine aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00380 Tryptophan metabolism [PATH:mka00380]
D MK0849 lpd; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D MK1378 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:mka00400]
D MK1409 fbaB; Fructose-1,6-bisphosphate aldolase of the DhnA family K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D MK1408 Predicted alternative 3-dehydroquinate synthase K11646 K11646; 3-dehydroquinate synthase II [EC:1.4.1.24]
D MK0429 aroD; 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]
D MK0117 aroE; Shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
D MK1610 Archaeal shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D MK0628 aroA; 5-enolpyruvylshikimate-3-phosphate synthase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D MK0631 aroC; Chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D MK0437 trpE; Anthranilate/para-aminobenzoate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D MK0436 pabA; Anthranilate/para-aminobenzoate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D MK0678 trpD; Anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D MK0508 trpF; Phosphoribosylanthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
D MK1391 trpC; Indole-3-glycerol phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D MK0403 trpA; Tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D MK0784 trpB; Tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D MK1609 pheA; Chorismate mutase K04093 pheA1; chorismate mutase [EC:5.4.99.5]
D MK0798 tyrA_2; Prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D MK0079 tyrA_1; Prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51]
D MK1426 hisC; Histidinol-phosphate/tyrosine aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:mka00410]
D MK1500 Pyridoxal-phosphate-dependent enzyme related to glutamate decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D MK0712 Uncharacterized protein conserved in archaea K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
C 00430 Taurine and hypotaurine metabolism
D MK1411 Predicted ornithine cyclodeaminase, mu-crystallin homolog K19244 ala; alanine dehydrogenase [EC:1.4.1.1]
C 00440 Phosphonate and phosphinate metabolism
C 00450 Selenocompound metabolism [PATH:mka00450]
D MK0667 metE; Methionine synthase II (cobalamin-independent) K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D MK1561 trxB; Thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D MK1369 selD; Predicted enzyme related to selenophosphate synthase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D MK1679 Predicted nucletide kinase K10837 PSTK; O-phosphoseryl-tRNA(Sec) kinase [EC:2.7.1.164]
D MK0620 selA; Selenocysteine synthase K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1]
D MK0672 Pyridoxal-phosphate-dependent enzyme related to glutamate decarboxylase K03341 SEPSECS; O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase [EC:2.9.1.2]
D MK0850 metG; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism
D MK0122 glyA; Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:mka00470]
D MK0790 purL_1; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase subunit K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D MK0995 murD_1; UDP-N-acetylmuramoylalanine-D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D MK1047 murD_2; UDP-N-acetylmuramoylalanine-D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D MK0569 Uncharacterized conserved protein K26272 dgcN; D-glutamate N-acetyltransferase [EC:2.3.1.312]
D MK0568 Predicted enzyme related to O-succinylbenzoate synthase K19802 ycjG; L-Ala-D/L-Glu epimerase / N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25]
D MK0434 dapF; Diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D MK0483 lysA; Diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
C 00480 Glutathione metabolism [PATH:mka00480]
D MK0961 speE; Spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis
C 00550 Peptidoglycan biosynthesis
C 00552 Teichoic acid biosynthesis [PATH:mka00552]
D MK1212 Uncharacterized conserved protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:mka00730]
D MK0106 thiC; Thiamine biosynthesis protein ThiC K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D MK0589 thiD; Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase fused to uncharacterized conserved domain K21219 thiDN; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]
D MK0908 thiI_2; ATP pyrophosphatase involved in thiamine biosynthesis K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D MK0778 thiI_1; Thiamine biosynthesis ATP pyrophosphatase K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D MK0430 Flavoprotein, possibly involved in thiazole biosynthesis K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59]
D MK0607 thiL; Thiamine monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D MK0827 Predicted nucleotide kinase K06928 NTPCR; nucleoside-triphosphatase [EC:3.6.1.15]
D MK0025 adkA; Archaeal adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:mka00740]
D MK0098 ribD; Pyrimidine reductase K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302]
D MK1397 ribB; 3,4-dihydroxy-2-butanone 4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
D MK0281 ribH; Riboflavin synthase beta-chain K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D MK0361 Archaeal-type riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D MK1398 Transcriptional regulator of the riboflavin/FAD biosynthetic operon K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161]
D MK0578 tagD; Cytidylyltransferase K14656 ribL; FAD synthetase [EC:2.7.7.2]
D MK1465 ubiX; 3-polyprenyl-4-hydroxybenzoate decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00750 Vitamin B6 metabolism [PATH:mka00750]
D MK0974 thrC; Threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D MK1371 snz1; Pyridoxine biosynthesis enzyme K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
D MK1062 pdx2; Predicted glutamine amidotransferase involved in pyridoxine biosynthesis K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
C 00760 Nicotinate and nicotinamide metabolism [PATH:mka00760]
D MK0094 Predicted dinucleotide-utilizing enzyme K06989 nadX; aspartate dehydrogenase [EC:1.4.1.21]
D MK0073 nadA; Quinolinate synthase K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D MK0446 nadC; Nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D MK1400 pncB; Nicotinic acid phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D MK0433 surE; Predicted acid phosphatase K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D MK1418 nadE; NAD synthase K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D MK1075 sir2; NAD-dependent protein deacetylase, SIR2 family K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313]
D MK0742 Predicted sugar kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
C 00770 Pantothenate and CoA biosynthesis [PATH:mka00770]
D MK0531 ilvB_2; Acetolactate synthase, large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D MK1236 Acetolactate synthase large subunit homolog K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D MK0545 ilvH; Acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D MK0832 ilvC; Ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D MK1197 ilvD; Dihydroxyacid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D MK0733 Predicted archaea-specific kinase of the sugar kinase superfamily K06982 pok; pantoate kinase [EC:2.7.1.169]
D MK0712 Uncharacterized protein conserved in archaea K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
D MK0713 dfp; Phosphopantothenoylcysteine synthetase/decarboxylase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D MK1504 Predicted nucleotidyltransferase of the HIGH superfamily K02201 E2.7.7.3B; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D MK1453 Uncharacterized protein conserved in archaea K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237]
D MK1627 ilvE; Branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D MK1500 Pyridoxal-phosphate-dependent enzyme related to glutamate decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
C 00780 Biotin metabolism
D MK0016 Predicted enzyme related to biotin synthase K01012 bioB; biotin synthase [EC:2.8.1.6]
C 00785 Lipoic acid metabolism [PATH:mka00785]
D MK0849 lpd; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00790 Folate biosynthesis [PATH:mka00790]
D MK0819 6-pyruvoyl-tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D MK0818 Organic-radical-activating enzyme K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D MK1065 Predicted PP-loop superfamily ATPase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D MK0485 Uncharacterized conserved protein K17488 mptA; GTP cyclohydrolase IV [EC:3.5.4.39]
D MK0390 Predicted HD-superfamily hydrolase K17487 mptB; 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase [EC:3.1.4.56]
D MK0786 Uncharacterized protein conserved in archaea K09739 mptD; dihydroneopterin aldolase [EC:4.1.2.25]
D MK1076 Uncharacterized Rossman fold enzyme K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D MK0558 Predicted archaeal-specific sugar kinase K06984 K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54]
D MK1079 Metal-dependent hydrolase of the beta-lactamase superfamily K06897 K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105]
D MK1323 Metal-dependent hydrolase of the beta-lactamase superfamily K06897 K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105]
D MK1574 Metal-dependent hydrolase of the beta-lactamase superfamily K06897 K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105]
D MK1484 Archaea-specific flavoprotein K18853 dmrX; dihydromethanopterin reductase (acceptor) [EC:1.5.99.15]
D MK1540 moaA; Molybdenum cofactor biosynthesis enzyme K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D MK0554 moaC; Molybdenum cofactor biosynthesis enzyme K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D MK0553 moaB; Molybdopterin biosynthesis enzyme K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D MK1524 moeA; Molybdopterin biosynthesis enzyme K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D MK1200 Uncharacterized, MobA-related protein K07141 mocA; molybdenum cofactor cytidylyltransferase [EC:2.7.7.76]
D MK0406 mobA; Molybdopterin-guanine dinucleotide biosynthesis protein A K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
C 00670 One carbon pool by folate [PATH:mka00670]
D MK0122 glyA; Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D MK1370 thyA; Thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
D MK1605 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:mka00860]
D MK0757 glnS; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D MK0200 hemA; Glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D MK0280 hemL; Glutamate-1-semialdehyde aminotransferase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D MK0198 hemB; Delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D MK0746 hemC; Porphobilinogen deaminase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D MK1550 hemD; Uroporphyrinogen-III synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D MK1548 cysG_2; Uroporphyrinogen-III methylase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
D MK1495 cysG_1; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76]
D MK0428 Uncharacterized conserved protein K22011 cfbA; sirohydrochlorin cobalto/nickelchelatase [EC:4.99.1.3 4.99.1.11]
D MK1038 cobF; Precorrin-2 methylase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151]
D MK1376 cobJ; Precorrin-3B methylase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272]
D MK1375 cobM; Precorrin-4 methylase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271]
D MK1518 cbiG; Cobalamin biosynthesis protein CbiG K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12]
D MK0334 cbiD; Cobalamin biosynthesis protein CbiD K02188 cbiD; cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195]
D MK1037 cobL_1; Precorrin-6B methylase K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196]
D MK1428 cobL_2; Precorrin-6B methylase K03399 cbiE; cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289]
D MK1196 cobH; Precorrin isomerase K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60]
D MK1643 cobB_2; Cobyrinic acid a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
D MK1573 cobB_1; Cobyrinic acid a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
D MK1351 Predicted protein of CobN/Mg-chelatase family K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D MK0663 Predicted protein of the CobN/Mg-chelatase family, a fragment K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D MK0664 Predicted protein of the CobN/Mg-chelatase family, a fragment K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D MK1534 Predicted protein of the CobN/Mg-chelatase family K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D MK1405 Predicted protein of the CobN/Mg-chelatase family K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D MK0134 Predicted protein of the CobN/Mg-chelatase family K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D MK1041 Predicted protein of the CobN/Mg-chelatase family K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D MK0509 Predicted protein of the CobN/Mg-chelatase family K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D MK1414 cobQ; Cobyric acid synthase K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10]
D MK1516 cbiB; Cobalamin biosynthesis protein CobD/CbiB K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
D MK1670 GTP:adenosylcobinamide-phosphate guanylyltransferase K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62]
D MK1671 cobS; Cobalamin-5-phosphate synthase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26]
D MK1385 nifD; Nitrogenase molybdenum-iron subunit K21611 cfbD; Ni-sirohydrochlorin a,c-diamide reductive cyclase subunit CfbD [EC:6.3.3.7]
D MK1590 murF; UDP-N-acetylmuramyl pentapeptide synthase K21612 cfbE; coenzyme F430 synthetase [EC:6.4.1.9]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis
D MK1465 ubiX; 3-polyprenyl-4-hydroxybenzoate decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:mka00900]
D MK1378 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D MK1379 pksG; 3-hydroxy-3-methylglutaryl CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D MK0355 hmg1; Hydroxymethylglutaryl-CoA reductase K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
D MK0993 erg12; Mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36]
D MK0777 Predicted archaeal kinase K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26]
D MK1639 Uncharacterized conserved protein K25517 acnX1; phosphomecalonate degydratase large subunit [EC:4.2.1.182]
D MK1486 Uncharacterized conserved protein K09128 acnX2; phosphomecalonate degydratase small subunit [EC:4.2.1.182]
D MK0234 ubiD; Predicted decarboxylase related 3-polyprenyl-4-hydroxybenzoate decarboxylase K25518 E4.1.1.126; anhydromevalonate phosphate decarboxylase [EC:4.1.1.126]
D MK1465 ubiX; 3-polyprenyl-4-hydroxybenzoate decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D MK0776 lldD; L-lactate dehydrogenase (FMN-dependent) K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D MK0774 ispA; Geranylgeranyl pyrophosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D MK0767 uppS; Undecaprenyl pyrophosphate synthase K15888 uppS; tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] [EC:2.5.1.89]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis
D MK0892 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis; translation initiation factor eIF2B subunit K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis
C 00261 Monobactam biosynthesis [PATH:mka00261]
D MK0109 lysC; Aspartokinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D MK1389 asd; Aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D MK1607 dapA; Dihydrodipicolinate synthase/N-acetylneuraminate lyase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D MK1422 dapB; Dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:mka00521]
D MK0920 cpsG_2; Phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D MK0741 suhB; Archaea-specific fructose-1,6-bisphosphatase fused to predicted pyrophosphatase of the PRA-PH family K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D MK0892 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis; translation initiation factor eIF2B subunit K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
C 00525 Acarbose and validamycin biosynthesis
D MK0892 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis; translation initiation factor eIF2B subunit K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
C 00401 Novobiocin biosynthesis [PATH:mka00401]
D MK0798 tyrA_2; Prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D MK1426 hisC; Histidinol-phosphate/tyrosine aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D MK0437 trpE; Anthranilate/para-aminobenzoate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D MK0436 pabA; Anthranilate/para-aminobenzoate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
C 00999 Biosynthesis of various plant secondary metabolites [PATH:mka00999]
D MK1508 Uncharacterized conserved protein K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D MK0117 aroE; Shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation
D MK1378 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00627 Aminobenzoate degradation
D MK1465 ubiX; 3-polyprenyl-4-hydroxybenzoate decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation
D MK1416 nifH; Nitrogenase subunit NifH (ATPase) K02588 nifH; nitrogenase iron protein NifH
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
C 00633 Nitrotoluene degradation [PATH:mka00633]
D MK0536 carbon monoxide dehydrogenase catalytic subunit K00198 cooS; anaerobic carbon-monoxide dehydrogenase catalytic subunit [EC:1.2.7.4]
D MK0084 Fe-S-cluster-containing hydrogenase component K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit
D MK0082 porA_1; Pyruvate:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D MK0083 porB_1; Pyruvate:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D MK0080 porG_1; Pyruvate:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D MK0081 porD; Pyruvate:ferredoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:mka03020]
D MK0686 rpoB_1; DNA-directed RNA polymerase second-largest subunit, the N-terminal part K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
D MK0687 rpoB_2; DNA-directed RNA polymerase second-largest subunit, the N-terminal part K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D MK0685 rpoC_2; DNA-directed RNA polymerase largest subunit, the C-terminal part K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D MK0684 rpoC_1; DNA-directed RNA polymerase largest subunit, the N-terminal part K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D MK1474 rpoA; DNA-directed RNA polymerase alpha subunit K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D MK0058 rpb11; DNA-directed RNA polymerase, subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D MK1451 rpoE1; DNA-directed RNA polymerase subunit E' K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D MK1659 Uncharacterized protein conserved in archaea K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D MK0688 rpb5; DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D MK1580 rpoZ; DNA-directed RNA polymerase subunit K/omega K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D MK1478 rpb10; DNA-directed RNA polymerase, subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D MK0378 rPC10; DNA-directed RNA polymerase subunit RPC10 K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
C 03022 Basal transcription factors [PATH:mka03022]
D MK0858 sua7_2; Transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D MK0619 sua7_1; Transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D MK0839 spt15; Transcription initiation factor TFIID (TATA-binding protein) K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D MK0495 tfa1; Transcription initiation factor IIE, large subunit K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:mka03010]
D MK1578 rpsB; Ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D MK0842 rpsC; Ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D MK1472 rpsD; Ribosomal protein related to S4 K02986 RP-S4; small subunit ribosomal protein S4
D MK0029 rpsE; Ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D MK0680 rpsG; Ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D MK1223 rpsH; Ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D MK1477 rpsI; Ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D MK0246 rpsJ; Ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D MK1473 rpsK; Ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D MK0681 rpsL; Ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D MK1471 rpsM; Ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D MK1222 rpsN; Ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D MK1593 rpsO; Ribosomal protein S15P/S13E K02956 RP-S15; small subunit ribosomal protein S15
D MK1217 rpsQ; Ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D MK0990 rpsS; Ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D MK1461 rps1A; Ribosomal protein S3AE K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D MK1220 rps4A; Ribosomal protein S4E K02987 RP-S4e; small subunit ribosomal protein S4e
D MK1446 rps6A; Ribosomal protein S6E (S10) K02991 RP-S6e; small subunit ribosomal protein S6e
D MK1545 rps8A; Ribosomal protein S8E K02995 RP-S8e; small subunit ribosomal protein S8e
D MK1608 rps17A; Ribosomal protein S17E K02962 RP-S17e; small subunit ribosomal protein S17e
D MK1620 rps19A; Ribosomal protein S19E (S16A) K02966 RP-S19e; small subunit ribosomal protein S19e
D MK1454 rps24A; Ribosomal protein S24E K02974 RP-S24e; small subunit ribosomal protein S24e
D MK0125 Zn-ribbon containing protein K02976 RP-S26e; small subunit ribosomal protein S26e
D MK0418 rps27A; Ribosomal protein S27E K02978 RP-S27e; small subunit ribosomal protein S27e
D MK1455 rps31; Ribosomal protein S27AE K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D MK1445 rps28A; Ribosomal protein S28E/S33 K02979 RP-S28e; small subunit ribosomal protein S28e
D MK0825 rplA; Ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D MK0412 rplB; Ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D MK0415 rplC; Ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D MK1221 rplE; Ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D MK1224 rplF; Ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D MK0826 rplJ; Ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D MK0824 rplK; Ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D MK0004 rpp1A; Ribosomal protein L12E/L44/L45 K02869 RP-L12; large subunit ribosomal protein L12
D MK1476 rplM; Ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D MK1218 rplN; Ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D MK0027 rplO; Ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D MK0030 rplR; Ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D MK0841 rplV; Ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D MK0413 rplW; Ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D MK1219 rplX; Ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D MK0843 rpmC; Ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D MK0028 rpmD; Ribosomal protein L30/L7E K02907 RP-L30; large subunit ribosomal protein L30
D MK0414 rplD; Ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e
D MK1598 rpl8A; Ribosomal protein HS6-type (S12/L30/L7a) K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D MK0251 rplP; Ribosomal protein L16/L10E K02866 RP-L10e; large subunit ribosomal protein L10e
D MK0833 rpl14A; Ribosomal protein L14E K02875 RP-L14e; large subunit ribosomal protein L14e
D MK0389 rpl15A; Ribosomal protein L15E K02877 RP-L15e; large subunit ribosomal protein L15e
D MK1475 rpl18A; Ribosomal protein L18E K02883 RP-L18e; large subunit ribosomal protein L18e
D MK0031 rpl19A; Ribosomal protein L19E K02885 RP-L19e; large subunit ribosomal protein L19e
D MK1660 rpl21A; Ribosomal protein L21E K02889 RP-L21e; large subunit ribosomal protein L21e
D MK1444 rpl24A; Ribosomal protein L24E K02896 RP-L24e; large subunit ribosomal protein L24e
D MK0683 rpl30; Ribosomal protein L30E K02908 RP-L30e; large subunit ribosomal protein L30e
D MK1617 rpl31A; Ribosomal protein L31E K02910 RP-L31e; large subunit ribosomal protein L31e
D MK1225 rpl32; Ribosomal protein L32E K02912 RP-L32e; large subunit ribosomal protein L32e
D MK0023 rpl34A; Ribosomal protein L34E K02915 RP-L34e; large subunit ribosomal protein L34e
D MK0155 Ribosomal protein L35AE/L33A K02917 RP-L35Ae; large subunit ribosomal protein L35Ae
D MK0221 rpl37A; Ribosomal protein L37E K02922 RP-L37e; large subunit ribosomal protein L37e
D MK0379 rpl43A; Ribosomal protein L37AE/L43A K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D MK1618 rpl39; Ribosomal protein L39E K02924 RP-L39e; large subunit ribosomal protein L39e
D MK0641 rpl40A; Ribosomal protein L40E K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D MK0417 rpl42A; Ribosomal protein L44E K02929 RP-L44e; large subunit ribosomal protein L44e
D MK1615 rpl20A; Ribosomal protein L20A (L18A) K02944 RP-LX; large subunit ribosomal protein LX
D MKr02 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D MKr03 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D MKr01 5S ribisomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:mka00970]
D MKt02 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D MKt12 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D MKt13 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D MKt23 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D MKt34 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D MKt22 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D MKt18 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D MKt25 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D MKt06 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D MKt26 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D MKt33 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D MKt01 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D MKt30 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D MKt21 tRNA-His K14226 tRNA-His; tRNA His
D MKt03 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D MKt14 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D MKt17 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D MKt19 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D MKt20 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D MKt10 tRNA-Met K14230 tRNA-Met; tRNA Met
D MKt05 tRNA-Met K14230 tRNA-Met; tRNA Met
D MKt11 tRNA-Met K14230 tRNA-Met; tRNA Met
D MKt31 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D MKt27 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D MKt32 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D MKt15 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D MKt28 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D MKt35 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D MKt08 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D MKt24 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D MKt04 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D MKt29 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D MKt16 tRNA-Val K14237 tRNA-Val; tRNA Val
D MKt09 tRNA-Val K14237 tRNA-Val; tRNA Val
D MK0757 glnS; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D MK0238 gatA; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D MK0960 gatB; Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D MK0359 gatC; Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D MK1509 ansB; L-asparaginase K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7]
D MK0129 gatE; Archaeal Glu-tRNAGln amidotransferase subunit E K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7]
D MK0900 alaS; Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D MK0710 asnS; Aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D MK0152 grs1; Glycyl-tRNA synthetase, class II K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D MK0544 thrS; Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D MK1460 serS; Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D MK1679 Predicted nucletide kinase K10837 PSTK; O-phosphoseryl-tRNA(Sec) kinase [EC:2.7.1.164]
D MK0672 Pyridoxal-phosphate-dependent enzyme related to glutamate decarboxylase K03341 SEPSECS; O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase [EC:2.9.1.2]
D MK0620 selA; Selenocysteine synthase K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1]
D MK0439 Phenylalanyl-tRNA synthetase alpha subunit, archaeal type K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
D MK0229 Archaea-specific pyridoxal phosphate-dependent enzyme K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]
D MK1187 Predicted extracellular polysaccharide hydrolase of the endo alpha-1,4 polygalactosaminidase family K01884 cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
D MK1125 Predicted extracellular polysaccharide hydrolase of the Endo alpha-1,4 polygalactosaminidase family K01884 cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
D MK1100 Predicted extracellular polysaccharide hydrolase of the endo alpha-1,4 polygalactosaminidase family K01884 cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
D MK0850 metG; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D MK1424 valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D MK1364 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D MK0899 ileS; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D MK0986 lysS; Lysyl-tRNA synthetase (class I) K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D MK0758 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D MK1229 proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D MK1538 hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D MK0271 pheS; Phenylalanyl-tRNA synthetase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D MK0820 pheT; Phenylalanyl-tRNA synthetase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D MK0516 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D MK0343 trpS; Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:mka03060]
D MK0026 secY; Preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D MK1009 secD; Preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D MK1008 secF; Preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D MK1612 ffh; Signal recognition particle GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D MK1613 ftsY; Signal recognition particle GTPase K03110 ftsY; fused signal recognition particle receptor
D MK0822 sss1; Protein translocase subunit Sss1 K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D MK1551 sec65; 19 kDa subunit of the signal recognition particle K03105 SRP19; signal recognition particle subunit SRP19
D MK1680 arsA; Arsenite transporting ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D MK1201 tatA; Sec-independent protein secretion pathway component K03116 tatA; sec-independent protein translocase protein TatA
D MK1031 lepB; Type I signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:mka04122]
D MK0257 Predicted redox protein, regulator of disulfide bond formation K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D MK1540 moaA; Molybdenum cofactor biosynthesis enzyme K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D MK0554 moaC; Molybdenum cofactor biosynthesis enzyme K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D MK0553 moaB; Molybdopterin biosynthesis enzyme K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D MK0908 thiI_2; ATP pyrophosphatase involved in thiamine biosynthesis K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D MK0778 thiI_1; Thiamine biosynthesis ATP pyrophosphatase K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
C 03050 Proteasome [PATH:mka03050]
D MK0878 rpt1; ATP-dependent 26S proteasome regulatory subunit K03420 psmR; proteasome regulatory subunit
D MK0385 hslV_1; Protease subunit of the proteasome K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D MK1228 hslV_2; Protease subunit of the proteasome K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
C 03018 RNA degradation [PATH:mka03018]
D MK0060 Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain) K07573 CSL4; exosome complex component CSL4
D MK0382 rrp4; Predicted exosome subunit, RNA-binding protein Rrp4 (contain S1 domain and KH domain) K03679 RRP4; exosome complex component RRP4
D MK0380 Predicted exosome subunit, predicted exoribonuclease related to RNase PH K12589 RRP42; exosome complex component RRP42
D MK0381 rph; Predicted exosome subunit, RNase PH K11600 RRP41; exosome complex component RRP41
D MK1647 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D MK0775 Predicted hydrolase of the metallo-beta-lactamase superfamily K12574 rnj; ribonuclease J [EC:3.1.-.-]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:mka03030]
D MK0617 dnaG; Predicted bacterial-type DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D MK0186 rnhB; Ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D MK1039 polB; B family DNA polymerase K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D MK1583 hys2; Archaeal DNA polymerase II small subunit, predicted phosphatase K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D MK1650 Archaeal DNA polymerase II, large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D MK0965 mcm2_1; Predicted ATPase involved in replication control, Cdc46/Mcm family K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D MK1120 mcm2_2; Predicted ATPase involved in replication control, Cdc46/Mcm family K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D MK0586 pri1; Eukaryotic-type DNA primase, small subunit K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D MK1394 pri2; Eukaryotic-type DNA primase, large subunit K18882 priL; DNA primase large subunit
D MK1030 dnaN; DNA polymerase sliding clamp (PCNA) K04802 PCNA; proliferating cell nuclear antigen
D MK0006 Replication factor C (ATPase involved in DNA replication) intein containing K04801 rfcS; replication factor C small subunit
D MK0005 Replication factor C (ATPase involved in DNA replication) K04800 rfcL; replication factor C large subunit
D MK0566 exo; 5'-3' exonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D MK0999 cdc9; ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03410 Base excision repair [PATH:mka03410]
D MK0193 nth_1; Predicted EndoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D MK1362 nth_2; A/G-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D MK1030 dnaN; DNA polymerase sliding clamp (PCNA) K04802 PCNA; proliferating cell nuclear antigen
D MK0566 exo; 5'-3' exonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D MK0999 cdc9; ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D MK0061 recJ; Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D MK1592 recJ_1; Single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D MK0204 recJ_1; Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
C 03420 Nucleotide excision repair [PATH:mka03420]
D MK1030 dnaN; DNA polymerase sliding clamp (PCNA) K04802 PCNA; proliferating cell nuclear antigen
D MK0999 cdc9; ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03430 Mismatch repair [PATH:mka03430]
D MK0061 recJ; Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D MK1592 recJ_1; Single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D MK0204 recJ_1; Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D MK1030 dnaN; DNA polymerase sliding clamp (PCNA) K04802 PCNA; proliferating cell nuclear antigen
D MK0999 cdc9; ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03440 Homologous recombination
D MK0061 recJ; Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D MK1592 recJ_1; Single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D MK0204 recJ_1; Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
C 03450 Non-homologous end-joining
D MK0566 exo; 5'-3' exonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
D MK1452 rpoE2; DNA-directed RNA polymerase subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4
D MK0823 nusG; Transcription antiterminator NusG K15172 SUPT5H; transcription elongation factor SPT5
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus and Lyssavirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:mka02010]
D MK0601 Homolog of ABC-type nitrate/sulfonate/taurine/bicarbonate transport systems, periplasmic component K15553 ssuA; sulfonate transport system substrate-binding protein
D MK0602 Homolog of ABC-type nitrate/sulfonate/taurine/bicarbonate transport systems, permease component K15554 ssuC; sulfonate transport system permease protein
D MK0603 Homolog of ABC-type nitrate/sulfonate/taurine/bicarbonate transport systems, ATPase component K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D MK1521 ABC-type molybdate transport system, periplasmic component K02020 modA; molybdate transport system substrate-binding protein
D MK1522 ABC-type molybdate transport systems, permease component K02018 modB; molybdate transport system permease protein
D MK1523 ABC-type molibdate transport systems, ATPase component K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5]
D MK1690 pstS; ABC-type phosphate transport system, periplasmic component K02040 pstS; phosphate transport system substrate-binding protein
D MK1688 pstA; ABC-type phosphate transport system, permease component K02037 pstC; phosphate transport system permease protein
D MK1687 pstB; ABC-type phosphate transport system, ATPase component K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D MK0180 cbiM; Cobalamin biosynthesis protein CbiM K02007 cbiM; cobalt/nickel transport system permease protein
D MK0181 cbiQ; ABC-type cobalt transport system, permease component K02008 cbiQ; cobalt/nickel transport system permease protein
D MK0182 cbiO; ABC-type cobalt transport system, ATPase component K02006 cbiO; cobalt/nickel transport system ATP-binding protein
C 02060 Phosphotransferase system (PTS)
C 03070 Bacterial secretion system [PATH:mka03070]
D MK1009 secD; Preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D MK1008 secF; Preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D MK0026 secY; Preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D MK1613 ftsY; Signal recognition particle GTPase K03110 ftsY; fused signal recognition particle receptor
D MK1612 ffh; Signal recognition particle GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D MK1201 tatA; Sec-independent protein secretion pathway component K03116 tatA; sec-independent protein translocase protein TatA
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:mka02020]
D MK1690 pstS; ABC-type phosphate transport system, periplasmic component K02040 pstS; phosphate transport system substrate-binding protein
D MK0876 citG_2; Triphosphoribosyl-dephospho-CoA synthetase K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]
D MK0196 citG_1; Triphosphoribosyl-dephospho-CoA synthetase K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]
D MK0054 Nitrogen regulatory protein PII K04751 glnB; nitrogen regulatory protein P-II 1
D MK1087 Nitrogen regulatory protein PII homolog K04751 glnB; nitrogen regulatory protein P-II 1
D MK0338 glnA; Glutamine synthase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D MK1378 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:mka02024]
D MK0437 trpE; Anthranilate/para-aminobenzoate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D MK0436 pabA; Anthranilate/para-aminobenzoate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D MK0026 secY; Preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D MK1613 ftsY; Signal recognition particle GTPase K03110 ftsY; fused signal recognition particle receptor
D MK1612 ffh; Signal recognition particle GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D MK1647 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance
C 01502 Vancomycin resistance [PATH:mka01502]
D MK0753 mraY; UDP-N-acetylmuramyl pentapeptide phosphotransferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D MK0372 murG; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D MK0977 Glycosyl transferase, related to UDP-glucuronosyltransferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
C 01503 Cationic antimicrobial peptide (CAMP) resistance
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:mka01000]
C 01001 Protein kinases [BR:mka01001]
D MK1456 Mn2+-dependent serine/threonine protein kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D MK0514 rIO1_1; Predicted serine/threonine protein kinase K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D MK1399 rIO1_2; Predicted serine/threonine protein kinase K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D MK1000 Predicted serine/threonine protein kinase K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D MK0674 RIO1-like serine/threonine protein kinase fused to an N-terminal DNA-binding HTH domain K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
C 01009 Protein phosphatases and associated proteins [BR:mka01009]
D MK0967 gcd7; Translation initiation factor eIF-2 K03238 EIF2S2; translation initiation factor 2 subunit 2
D MK0121 serB; Phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C 01002 Peptidases and inhibitors [BR:mka01002]
D MK0363 guaA_1; PP-ATPase subunit of GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D MK0551 guaA_2; Glutamine amidotransferase subunit of GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D MK1649 purF; Glutamine phosphoribosylpyrophosphate amidotransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D MK0127 glmS; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domain K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D MK0918 agaS; Predicted phosphosugar isomerase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D MK0103 asnB; Asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D MK0158 srtA; Sortase (surface protein transpeptidase) K07284 srtA; sortase A [EC:3.4.22.70]
D MK1581 Predicted deacylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D MK0613 map; Methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D MK0223 pepP; Xaa-Pro aminopeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D MK0503 Predicted aminopeptidase K19701 ywaD; aminopeptidase YwaD [EC:3.4.11.6 3.4.11.10]
D MK0360 ampS; Leucyl aminopeptidase (aminopeptidase T) K19689 ampS; aminopeptidase [EC:3.4.11.-]
D MK0171 htpX; Zn-dependent protease with chaperone function K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D MK0548 Predicted Zn-dependent protease K06974 amzA; archaemetzincin [EC:3.4.-.-]
D MK0616 lonB; Predicted ATP-dependent protease K04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53]
D MK1031 lepB; Type I signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D MK0385 hslV_1; Protease subunit of the proteasome K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D MK1228 hslV_2; Protease subunit of the proteasome K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D MK0958 pmbA; Inactivated homologs of predicted Zn-dependent protease of TldD family (PmbA subfamily protein) K03592 pmbA; PmbA protein
D MK0957 tldD; Predicted Zn-dependent protease of TldD family K03568 tldD; TldD protein
C 01003 Glycosyltransferases [BR:mka01003]
D MK0880 Glycosyltransferase involved in cell wall biogenesis K00721 DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83]
D MK1083 Predicted glycosyltransferase K21011 pelF; polysaccharide biosynthesis protein PelF
D MK1306 Predicted glycosyltransferase K21011 pelF; polysaccharide biosynthesis protein PelF
C 01005 Lipopolysaccharide biosynthesis proteins [BR:mka01005]
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:mka01011]
D MK0755 murC; UDP-N-acetylmuramate-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D MK0995 murD_1; UDP-N-acetylmuramoylalanine-D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D MK1047 murD_2; UDP-N-acetylmuramoylalanine-D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D MK0752 murE_1; UDP-N-acetylmuramyl tripeptide synthase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D MK0753 mraY; UDP-N-acetylmuramyl pentapeptide phosphotransferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D MK0372 murG; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D MK0977 Glycosyl transferase, related to UDP-glucuronosyltransferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D MK1212 Uncharacterized conserved protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D MK0158 srtA; Sortase (surface protein transpeptidase) K07284 srtA; sortase A [EC:3.4.22.70]
C 01004 Lipid biosynthesis proteins [BR:mka01004]
D MK1246 Acyl-CoA synthetase (NDP forming) K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13]
D MK1023 Acyl-CoA synthetase (NDP forming) K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:mka01006]
D MK0774 ispA; Geranylgeranyl pyrophosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
C 01007 Amino acid related enzymes [BR:mka01007]
D MK0986 lysS; Lysyl-tRNA synthetase (class I) K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D MK0757 glnS; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D MK0516 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D MK0343 trpS; Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D MK0758 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D MK0850 metG; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D MK0899 ileS; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D MK1424 valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D MK1364 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D MK0710 asnS; Aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D MK1538 hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D MK0152 grs1; Glycyl-tRNA synthetase, class II K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D MK1460 serS; Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D MK1229 proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D MK0544 thrS; Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D MK0900 alaS; Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D MK0439 Phenylalanyl-tRNA synthetase alpha subunit, archaeal type K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
D MK0271 pheS; Phenylalanyl-tRNA synthetase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D MK0820 pheT; Phenylalanyl-tRNA synthetase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D MK1187 Predicted extracellular polysaccharide hydrolase of the endo alpha-1,4 polygalactosaminidase family K01884 cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
D MK1125 Predicted extracellular polysaccharide hydrolase of the Endo alpha-1,4 polygalactosaminidase family K01884 cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
D MK1100 Predicted extracellular polysaccharide hydrolase of the endo alpha-1,4 polygalactosaminidase family K01884 cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
D MK1426 hisC; Histidinol-phosphate/tyrosine aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D MK1606 argD; Pyridoxal-phosphate-dependent aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D MK0280 hemL; Glutamate-1-semialdehyde aminotransferase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D MK1627 ilvE; Branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D MK0156 Predicted pyridoxal-phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis K13010 per; perosamine synthetase [EC:2.6.1.102]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:mka03000]
D MK1520 dcm; Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D MK0839 spt15; Transcription initiation factor TFIID (TATA-binding protein) K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D MK1515 Predicted transcriptional regulator of the ArsR family K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D MK0175 troR; Mn-dependent transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D MK0337 Predicted transcriptonal regulator consisting of wHTH DNA-binding domain and an uncharacterized domain conserved in archaea K09720 nrpRI; HTH-type transcriptional regulator, global nitrogen regulator NrpRI
D MK0253 Predicted transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D MK1430 modE; N-terminal domain of molybdenum-binding protein K02019 modE; molybdate transport system regulatory protein
D MK1005 Predicted transcriptional regulator containing a cHTH DNA-binding domain K07728 K07728; putative transcriptional regulator
D MK1501 Predicted transcriptional regulator containing a DNA-binding HTH domain K07730 K07730; putative transcriptional regulator
D MK1380 Predicted transcriptional regulator containing a DNA-binding HTH domain K07731 K07731; putative transcriptional regulator
D MK1502 Predicted transcriptional regulator containing the CopG/Arc/MetJ DNA-binding domain and a 3H domain K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
C 03021 Transcription machinery [BR:mka03021]
D MK0858 sua7_2; Transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D MK0619 sua7_1; Transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D MK0839 spt15; Transcription initiation factor TFIID (TATA-binding protein) K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D MK0495 tfa1; Transcription initiation factor IIE, large subunit K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D MK1452 rpoE2; DNA-directed RNA polymerase subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4
D MK0823 nusG; Transcription antiterminator NusG K15172 SUPT5H; transcription elongation factor SPT5
D MK0682 nusA_1; Transcription elongation factor NusA K02600 nusA; transcription termination/antitermination protein NusA
D MK0685 rpoC_2; DNA-directed RNA polymerase largest subunit, the C-terminal part K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D MK0684 rpoC_1; DNA-directed RNA polymerase largest subunit, the N-terminal part K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D MK0686 rpoB_1; DNA-directed RNA polymerase second-largest subunit, the N-terminal part K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
D MK0687 rpoB_2; DNA-directed RNA polymerase second-largest subunit, the N-terminal part K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D MK1474 rpoA; DNA-directed RNA polymerase alpha subunit K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D MK1451 rpoE1; DNA-directed RNA polymerase subunit E' K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D MK1659 Uncharacterized protein conserved in archaea K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D MK0688 rpb5; DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D MK1580 rpoZ; DNA-directed RNA polymerase subunit K/omega K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D MK0058 rpb11; DNA-directed RNA polymerase, subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D MK1478 rpb10; DNA-directed RNA polymerase, subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D MK0378 rPC10; DNA-directed RNA polymerase subunit RPC10 K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
C 03019 Messenger RNA biogenesis [BR:mka03019]
D MK1452 rpoE2; DNA-directed RNA polymerase subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4
D MK0823 nusG; Transcription antiterminator NusG K15172 SUPT5H; transcription elongation factor SPT5
D MK0038 Predicted RNA-binding protein K06965 PELO; protein pelota
D MK0759 erf1; Peptide chain release factor eRF1 K03265 ETF1; peptide chain release factor subunit 1
D MK0247 GTPase, translation elongation factor K03231 EEF1A; elongation factor 1-alpha
D MK0060 Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain) K07573 CSL4; exosome complex component CSL4
D MK0382 rrp4; Predicted exosome subunit, RNA-binding protein Rrp4 (contain S1 domain and KH domain) K03679 RRP4; exosome complex component RRP4
D MK0381 rph; Predicted exosome subunit, RNase PH K11600 RRP41; exosome complex component RRP41
D MK0380 Predicted exosome subunit, predicted exoribonuclease related to RNase PH K12589 RRP42; exosome complex component RRP42
D MK0775 Predicted hydrolase of the metallo-beta-lactamase superfamily K12574 rnj; ribonuclease J [EC:3.1.-.-]
D MK1647 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D MK0835 Archaea-specific Superfamily II helicase K03725 K03725; putative ATP-dependent RNA helicase [EC:5.6.2.-]
C 03041 Spliceosome
C 03011 Ribosome [BR:mka03011]
D MK1461 rps1A; Ribosomal protein S3AE K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D MK1220 rps4A; Ribosomal protein S4E K02987 RP-S4e; small subunit ribosomal protein S4e
D MK1446 rps6A; Ribosomal protein S6E (S10) K02991 RP-S6e; small subunit ribosomal protein S6e
D MK1545 rps8A; Ribosomal protein S8E K02995 RP-S8e; small subunit ribosomal protein S8e
D MK1608 rps17A; Ribosomal protein S17E K02962 RP-S17e; small subunit ribosomal protein S17e
D MK1620 rps19A; Ribosomal protein S19E (S16A) K02966 RP-S19e; small subunit ribosomal protein S19e
D MK1454 rps24A; Ribosomal protein S24E K02974 RP-S24e; small subunit ribosomal protein S24e
D MK0125 Zn-ribbon containing protein K02976 RP-S26e; small subunit ribosomal protein S26e
D MK0418 rps27A; Ribosomal protein S27E K02978 RP-S27e; small subunit ribosomal protein S27e
D MK1455 rps31; Ribosomal protein S27AE K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D MK1445 rps28A; Ribosomal protein S28E/S33 K02979 RP-S28e; small subunit ribosomal protein S28e
D MK0414 rplD; Ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e
D MK1598 rpl8A; Ribosomal protein HS6-type (S12/L30/L7a) K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D MK0251 rplP; Ribosomal protein L16/L10E K02866 RP-L10e; large subunit ribosomal protein L10e
D MK0833 rpl14A; Ribosomal protein L14E K02875 RP-L14e; large subunit ribosomal protein L14e
D MK0389 rpl15A; Ribosomal protein L15E K02877 RP-L15e; large subunit ribosomal protein L15e
D MK1475 rpl18A; Ribosomal protein L18E K02883 RP-L18e; large subunit ribosomal protein L18e
D MK0031 rpl19A; Ribosomal protein L19E K02885 RP-L19e; large subunit ribosomal protein L19e
D MK1660 rpl21A; Ribosomal protein L21E K02889 RP-L21e; large subunit ribosomal protein L21e
D MK1444 rpl24A; Ribosomal protein L24E K02896 RP-L24e; large subunit ribosomal protein L24e
D MK0683 rpl30; Ribosomal protein L30E K02908 RP-L30e; large subunit ribosomal protein L30e
D MK1617 rpl31A; Ribosomal protein L31E K02910 RP-L31e; large subunit ribosomal protein L31e
D MK1225 rpl32; Ribosomal protein L32E K02912 RP-L32e; large subunit ribosomal protein L32e
D MK0023 rpl34A; Ribosomal protein L34E K02915 RP-L34e; large subunit ribosomal protein L34e
D MK0155 Ribosomal protein L35AE/L33A K02917 RP-L35Ae; large subunit ribosomal protein L35Ae
D MK0221 rpl37A; Ribosomal protein L37E K02922 RP-L37e; large subunit ribosomal protein L37e
D MK0379 rpl43A; Ribosomal protein L37AE/L43A K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D MK1618 rpl39; Ribosomal protein L39E K02924 RP-L39e; large subunit ribosomal protein L39e
D MK0641 rpl40A; Ribosomal protein L40E K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D MK0417 rpl42A; Ribosomal protein L44E K02929 RP-L44e; large subunit ribosomal protein L44e
D MK1578 rpsB; Ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D MK0842 rpsC; Ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D MK1472 rpsD; Ribosomal protein related to S4 K02986 RP-S4; small subunit ribosomal protein S4
D MK0029 rpsE; Ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D MK0680 rpsG; Ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D MK1223 rpsH; Ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D MK1477 rpsI; Ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D MK0246 rpsJ; Ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D MK1473 rpsK; Ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D MK0681 rpsL; Ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D MK1471 rpsM; Ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D MK1222 rpsN; Ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D MK1593 rpsO; Ribosomal protein S15P/S13E K02956 RP-S15; small subunit ribosomal protein S15
D MK1217 rpsQ; Ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D MK0990 rpsS; Ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D MK0825 rplA; Ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D MK0412 rplB; Ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D MK0415 rplC; Ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D MK1221 rplE; Ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D MK1224 rplF; Ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D MK0826 rplJ; Ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D MK0824 rplK; Ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D MK1476 rplM; Ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D MK1218 rplN; Ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D MK0027 rplO; Ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D MK0030 rplR; Ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D MK0841 rplV; Ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D MK0413 rplW; Ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D MK1219 rplX; Ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D MK0843 rpmC; Ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D MK0028 rpmD; Ribosomal protein L30/L7E K02907 RP-L30; large subunit ribosomal protein L30
D MK0004 rpp1A; Ribosomal protein L12E/L44/L45 K02869 RP-L12; large subunit ribosomal protein L12
D MK1615 rpl20A; Ribosomal protein L20A (L18A) K02944 RP-LX; large subunit ribosomal protein LX
D MKr01 5S ribisomal RNA K01985 5SrRNA; 5S ribosomal RNA
D MKr02 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D MKr03 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:mka03009]
D MK0559 sik1; Protein implicated in ribosomal biogenesis, Nop56p homolog K14564 NOP56; nucleolar protein 56
D MK0133 truB; Pseudouridine synthase of the TruB family K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
D MK0420 Predicted Zn-ribbon-containing RNA-binding protein K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D MK0377 imp4; Predicted exosome subunit containing the IMP4 domain present in small nuclear ribonucleoprotein K14561 IMP4; U3 small nucleolar ribonucleoprotein protein IMP4
D MK0202 mra1; Uncharacterized conserved protein K14568 EMG1; rRNA small subunit pseudouridine methyltransferase Nep1 [EC:2.1.1.260]
D MK0513 Predicted RNA-binding protein containing KH domain) K06961 KRR1; ribosomal RNA assembly protein
D MK0514 rIO1_1; Predicted serine/threonine protein kinase K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D MK1399 rIO1_2; Predicted serine/threonine protein kinase K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D MK1000 Predicted serine/threonine protein kinase K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D MK0674 RIO1-like serine/threonine protein kinase fused to an N-terminal DNA-binding HTH domain K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D MK1060 Predicted nucleotide kinase related to CMP and AMP kinase K18532 AK6; adenylate kinase [EC:2.7.4.3]
D MK0638 Uncharacterized conserved protein K09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157]
D MK0091 Predicted ABC-class ATPase, RNase L inhibitor homolog K06174 ABCE1; ATP-binding cassette, sub-family E, member 1
D MK0003 Predicted GTPase K06943 NOG1; nucleolar GTP-binding protein
D MK1216 pop4_2; RNAse P subunit P29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D MK0846 pop4_1; RNAse P subunit P29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D MK0386 pop5; Predicted exosome subunit, RNase P subunit P14 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D MK0387 rpp30; Ribonuclease P subunit Rpp30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D MK0077 Predicted GTPase or GTP-binding protein K06947 GRC3; polynucleotide 5'-hydroxyl-kinase GRC3/NOL9 [EC:2.7.1.-]
D MK1616 tif6; Translation initiation factor 6 (EIF6) K03264 EIF6; translation initiation factor 6
D MK0517 nmd3; NMD protein affecting ribosome stability and mRNA decay K07562 NMD3; 60S ribosomal export protein NMD3
D MK0384 Predicted exosome subunit K14574 SDO1; ribosome maturation protein SDO1
D MK0608 nip7; Predicted RNA-binding protein involved in ribosomal biogenesis, contains PUA domain K07565 NIP7; 60S ribosome subunit biogenesis protein NIP7
D MK0036 Small, Ras-like GTPase K03595 era; GTPase
D MK0164 Small, Ras-like GTPase K03595 era; GTPase
D MK0560 nop1; Fibrillarin-like rRNA methylase K04795 flpA; fibrillarin-like pre-rRNA processing protein
D MK1598 rpl8A; Ribosomal protein HS6-type (S12/L30/L7a) K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D MK0859 gar1; RNA-binding protein involved in rRNA processing K07569 gar1; RNA-binding protein
D MK0682 nusA_1; Transcription elongation factor NusA K02600 nusA; transcription termination/antitermination protein NusA
D MK0934 ksgA; Dimethyladenosine transferase (rRNA methylase) K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D MK0295 tRNA/rRNA cytosine-C5-methylase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]
D MK0444 tRNA/rRNA cytosine-C5-methylase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]
D MK1575 tRNA/rRNA cytosine-C5-methylase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]
D MK0043 tRNA/rRNA cytosine-C5-methylase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]
D MK1630 tRNA/rRNA cytosine-C5-methylase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]
D MK1539 tRNA/rRNA cytosine-C5-methylase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]
D MK0709 rsmC; 16S rRNA G1207 methylase K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]
D MK1067 Predicted SAM-dependent methyltransferase K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]
D MK0549 Acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D MK0456 GTPase of the HflX family K03665 hflX; GTPase
D MK0635 sua5; Translation factor (SUA5) K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D MK1621 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein K07574 yhbY; RNA-binding protein
D MK0373 Predicted GTPase, probable translation factor K06942 ychF; ribosome-binding ATPase
D MK0499 Predicted ribonuclease of the G/E family K22469 fau-1; probable ribonuclease FAU-1 [EC:3.1.26.-]
C 03016 Transfer RNA biogenesis [BR:mka03016]
D MK1216 pop4_2; RNAse P subunit P29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D MK0846 pop4_1; RNAse P subunit P29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D MK0386 pop5; Predicted exosome subunit, RNase P subunit P14 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D MK0387 rpp30; Ribonuclease P subunit Rpp30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D MK1622 rpr2; RNAse P subunit RPR2 K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
D MK1033 Metal-dependent hydrolase of the beta-lactamase superfamily K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D MK1682 rtcB; Uncharacterized conserved protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D MK0228 Uncharacterized conserved protein K24956 ZBTB8OS; protein archease
D MK0247 GTPase, translation elongation factor K03231 EEF1A; elongation factor 1-alpha
D MK0757 glnS; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D MK1229 proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D MK0899 ileS; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D MK1364 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D MK0850 metG; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D MK0758 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D MK0900 alaS; Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D MK0152 grs1; Glycyl-tRNA synthetase, class II K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D MK0544 thrS; Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D MK1460 serS; Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D MK1424 valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D MK1538 hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D MK0271 pheS; Phenylalanyl-tRNA synthetase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D MK0820 pheT; Phenylalanyl-tRNA synthetase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D MK0516 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D MK0343 trpS; Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D MK0939 Uncharacterized protein conserved in archaea K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D MK1081 miaB; 2-methylthioadenine synthetase K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
D MK0154 trm1_1; N2,N2-dimethylguanosine tRNA methyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D MK0189 trm1_2; N2,N2-dimethylguanosine tRNA methyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D MK0599 Predicted methyltransferase K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D MK1415 Predicted SAM-dependent methyltransferase involved in tRNA-Met maturation K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D MK0151 Uncharacterized conserved protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D MK0055 Fe-S oxidoreductase K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D MK0940 Predicted SAM-dependent methyltransferase K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D MK0048 Uncharacterized conserved protein K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]
D MK0888 truA; Pseudouridylate synthase of the TruA family K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D MK0676 Uncharacterized conserved protein K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D MK1646 Predicted pseudouridylate synthase K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
D MK1456 Mn2+-dependent serine/threonine protein kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D MK1458 qri7; Metal-dependent protease with possible chaperone activity K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D MK1052 elp3; ELP3 component of the RNA polymerase II complex, consists of an N-terminal BioB/LipA-like domain and a C-terminal histone acetylase domain K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D MK0635 sua5; Translation factor (SUA5) K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D MK1369 selD; Predicted enzyme related to selenophosphate synthase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D MK1462 Predicted RNA-binding protein, contains THUMP domain K06963 TAN1; tRNA acetyltransferase TAN1
D MK0344 Predicted 23S rRNA methylase containing THUMP domain K06963 TAN1; tRNA acetyltransferase TAN1
D MK0402 Predicted RNA-binding protein containing THUMP domain K06963 TAN1; tRNA acetyltransferase TAN1
D MK0093 Uncharacterized conserved protein K10761 THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79]
D MK1237 Uncharacterized conserved protein K09006 K09006; RNA-free ribonuclease P [EC:3.1.26.5]
D MK1366 cca1; tRNA nucleotidyltransferase (CCA-adding enzyme) K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]
D MK0341 sen2_1; tRNA splicing endonuclease K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D MK0397 sen2_2; tRNA splicing endonuclease K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D MK1367 ligT; 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D MK1434 kptA; RNA:NAD 2'-phosphotransferase K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
D MK0986 lysS; Lysyl-tRNA synthetase (class I) K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D MK1187 Predicted extracellular polysaccharide hydrolase of the endo alpha-1,4 polygalactosaminidase family K01884 cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
D MK1125 Predicted extracellular polysaccharide hydrolase of the Endo alpha-1,4 polygalactosaminidase family K01884 cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
D MK1100 Predicted extracellular polysaccharide hydrolase of the endo alpha-1,4 polygalactosaminidase family K01884 cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
D MK0710 asnS; Aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D MK0439 Phenylalanyl-tRNA synthetase alpha subunit, archaeal type K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
D MK0229 Archaea-specific pyridoxal phosphate-dependent enzyme K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]
D MK1555 Uncharacterized protein K19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]
D MK0935 Predicted RNA-binding protein, contains THUMP domain K16930 cdat8; tRNA(cytosine8) deaminase [EC:3.5.4.35]
D MK0797 Predicted Fe-S oxidoreductase K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
D MK0932 Fe-S oxidoreductase family protein K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
D MK0519 lasT; rRNA methylase K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-]
D MK1018 Uncharacterized conserved protein K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257]
D MK0370 tRNA/rRNA cytosine-C5-methylase K22901 trm4; tRNA (cytosine40_48-C5)-methyltransferase [EC:2.1.1.-]
D MK0673 tRNA/rRNA cytosine-C5-methylase K22901 trm4; tRNA (cytosine40_48-C5)-methyltransferase [EC:2.1.1.-]
D MK1026 Uncharacterized conserved protein K15566 trm10; tRNA (adenine9-N1/guanine9-N1)-methyltransferase [EC:2.1.1.218 2.1.1.221]
D MK0969 Predicted N6-adenine-specific RNA methylase containing THUMP domain K16318 trm14; tRNA (guanine6-N2)-methyltransferase [EC:2.1.1.256]
D MK0894 Predicted DNA-modification methylase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]
D MK0803 SpoU-like RNA methylase K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]
D MK0144 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control K21947 ttuA; tRNA-5-methyluridine54 2-sulfurtransferase [EC:2.8.1.15]
D MK0257 Predicted redox protein, regulator of disulfide bond formation K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D MK0270 Uncharacterized conserved protein K09119 cgi121; KEOPS complex subunit Cgi121
D MK0376 Uncharacterized protein conserved in archaea K09741 pcc1; KEOPS complex subunit Pcc1
D MK1065 Predicted PP-loop superfamily ATPase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D MK0819 6-pyruvoyl-tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D MK0818 Organic-radical-activating enzyme K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D MK0188 tgt; Queuine/archaeosine tRNA-ribosyltransferase K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]
D MK0908 thiI_2; ATP pyrophosphatase involved in thiamine biosynthesis K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D MK0778 thiI_1; Thiamine biosynthesis ATP pyrophosphatase K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D MK1003 Predicted DNA-binding protein containing a Zn-ribbon K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]
D MK0146 Predicted P-loop ATPase fused to an acetyltransferase K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
C 03012 Translation factors [BR:mka03012]
D MK0515 infA; Translation initiation factor IF-1 K03236 EIF1A; translation initiation factor 1A
D MK0844 sui1; Translation initiation factor (SUI1) K03113 EIF1; translation initiation factor 1
D MK0419 sui2; Translation initiation factor eIF2-alpha K03237 EIF2S1; translation initiation factor 2 subunit 1
D MK0967 gcd7; Translation initiation factor eIF-2 K03238 EIF2S2; translation initiation factor 2 subunit 2
D MK1447 Translation elongation factor, GTPase K03242 EIF2S3; translation initiation factor 2 subunit 3
D MK0739 efp; Translation initiation factor eIF-5A K03263 EIF5A; translation initiation factor 5A
D MK1595 infB_2; Translation initiation factor 2, GTPase K03243 EIF5B; translation initiation factor 5B
D MK1616 tif6; Translation initiation factor 6 (EIF6) K03264 EIF6; translation initiation factor 6
D MK1564 infB_1; Translation initiation factor 2, GTPase K02519 infB; translation initiation factor IF-2
D MK0247 GTPase, translation elongation factor K03231 EEF1A; elongation factor 1-alpha
D MK0255 efb1; Translation elongation factor EF-1beta K03232 EEF1B; elongation factor 1-beta
D MK0679 fusA; Translation elongation and release factor (GTPase), contains an intein K03234 EEF2; elongation factor 2
D MK0148 GTPase - translation elongation factor K03833 selB; selenocysteine-specific elongation factor
D MK1517 dph2; Diphthamide synthase subunit DPH2 K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108]
D MK0644 Predicted ATPase of the PP-loop superfamily K06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14]
D MK0759 erf1; Peptide chain release factor eRF1 K03265 ETF1; peptide chain release factor subunit 1
D MK1491 Predicted rRNA/tRNA methylase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D MK1597 Uncharacterized conserved protein K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29]
C 03110 Chaperones and folding catalysts [BR:mka03110]
D MK1006 groL; HSP60 family chaperonin K22447 cct; archaeal chaperonin
D MK0002 ibpA; Molecular chaperone (small heat shock protein) K13993 HSP20; HSP20 family protein
D MK1614 gim5; Predicted prefoldin, molecular chaperone implicated in de novo protein folding K04797 pfdA; prefoldin alpha subunit
D MK0375 gimC; Prefoldin, chaperonin cofactor K04798 pfdB; prefoldin beta subunit
D MK1547 hybF; Zn-finger-containing protein HypA/HybF (possibly regulating hydrogenase expression) K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF
D MK1546 hypB_2; Ni2+-binding GTPase involved in regulation of expression and maturation of hydrogenase K04652 hypB; hydrogenase nickel incorporation protein HypB
D MK1231 slpA; FKBP-type peptidyl-prolyl cis-trans isomerase K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]
C 04131 Membrane trafficking [BR:mka04131]
D MK1591 ndk; Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D MK1680 arsA; Arsenite transporting ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D MK0822 sss1; Protein translocase subunit Sss1 K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D MK0247 GTPase, translation elongation factor K03231 EEF1A; elongation factor 1-alpha
C 04121 Ubiquitin system [BR:mka04121]
D MK0641 rpl40A; Ribosomal protein L40E K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D MK1455 rps31; Ribosomal protein S27AE K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
C 03051 Proteasome [BR:mka03051]
D MK0385 hslV_1; Protease subunit of the proteasome K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D MK1228 hslV_2; Protease subunit of the proteasome K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D MK0878 rpt1; ATP-dependent 26S proteasome regulatory subunit K03420 psmR; proteasome regulatory subunit
C 03032 DNA replication proteins [BR:mka03032]
D MK1030 dnaN; DNA polymerase sliding clamp (PCNA) K04802 PCNA; proliferating cell nuclear antigen
D MK0566 exo; 5'-3' exonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D MK0999 cdc9; ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D MK1520 dcm; Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D MK0420 Predicted Zn-ribbon-containing RNA-binding protein K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D MK0133 truB; Pseudouridine synthase of the TruB family K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
D MK0617 dnaG; Predicted bacterial-type DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D MK0965 mcm2_1; Predicted ATPase involved in replication control, Cdc46/Mcm family K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D MK1120 mcm2_2; Predicted ATPase involved in replication control, Cdc46/Mcm family K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D MK0586 pri1; Eukaryotic-type DNA primase, small subunit K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D MK1394 pri2; Eukaryotic-type DNA primase, large subunit K18882 priL; DNA primase large subunit
D MK0186 rnhB; Ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D MK1039 polB; B family DNA polymerase K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D MK1650 Archaeal DNA polymerase II, large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D MK1583 hys2; Archaeal DNA polymerase II small subunit, predicted phosphatase K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D MK0005 Replication factor C (ATPase involved in DNA replication) K04800 rfcL; replication factor C large subunit
D MK0006 Replication factor C (ATPase involved in DNA replication) intein containing K04801 rfcS; replication factor C small subunit
D MK0512 DNA topoisomerase VI, subunit A K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2]
D MK0921 DNA topoisomerase VI, subunit B K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]
D MK1604 topA; Topoisomerase IA K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D MK0049 rgyB; Reverse gyrase, subunit B K03170 topG; reverse gyrase [EC:5.6.2.2 5.6.2.-]
D MK0289 rgyA; Reverse gyrase, subunit A K03170 topG; reverse gyrase [EC:5.6.2.2 5.6.2.-]
C 03036 Chromosome and associated proteins [BR:mka03036]
D MK1520 dcm; Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D MK0137 Uncharacterized conserved protein K09142 SPOUT1; methyltransferase [EC:2.1.1.-]
D MK1677 hht1_3; Histone H3/H4 K24450 hmf; DNA-binding protein
D MK0821 ftsZ_1; FtsZ GTPase involved in cell division K03531 ftsZ; cell division protein FtsZ
D MK0218 ATPase involved in chromosome partitioning K03609 minD; septum site-determining protein MinD
D MK0168 mreB; HSP70 class molecular chaperones involved in cell morphogenesis K03569 mreB; rod shape-determining protein MreB and related proteins
D MK0240 ATPase involved in chromosome partitioning K03593 mrp; ATP-binding protein involved in chromosome partitioning
C 03400 DNA repair and recombination proteins [BR:mka03400]
D MK0130 ada; Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MK1362 nth_2; A/G-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D MK0193 nth_1; Predicted EndoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D MK1030 dnaN; DNA polymerase sliding clamp (PCNA) K04802 PCNA; proliferating cell nuclear antigen
D MK0566 exo; 5'-3' exonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D MK0999 cdc9; ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D MK1028 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MK1566 dcd_2; Deoxycytidine deaminase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D MK1435 nfi; Deoxyinosine 3'endonuclease (endonuclease V) K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D MK0061 recJ; Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D MK1592 recJ_1; Single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D MK0204 recJ_1; Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D MK0690 sbcC; SMC1-family ATPase involved in DNA repair K03546 sbcC; DNA repair protein SbcC/Rad50
D MK0691 sbcD; DNA repair exonuclease of the SbcD/Mre11-family K03547 sbcD; DNA repair protein SbcD/Mre11
D MK1312 Uncharacterized conserved protein K15342 cas1; CRISP-associated protein Cas1
D MK1442 radA_2; RadA recombinase K04483 radA; DNA repair protein RadA
D MK1032 radA_1; RadA recombinase K04483 radA; DNA repair protein RadA
D MK0102 Holliday junction resolvase, archaeal type K03552 hjr; holliday junction resolvase [EC:3.1.21.10]
D MK0111 Predicted Superfamily II helicase K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
D MK1604 topA; Topoisomerase IA K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D MK1035 lhr; Lhr-like Superfamily II helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D MK0040 Uncharacterized conserved protein K22585 nreA; DNA repair protein NreA
C 03029 Mitochondrial biogenesis [BR:mka03029]
D MK1564 infB_1; Translation initiation factor 2, GTPase K02519 infB; translation initiation factor IF-2
D MK1216 pop4_2; RNAse P subunit P29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D MK0846 pop4_1; RNAse P subunit P29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D MK0386 pop5; Predicted exosome subunit, RNase P subunit P14 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D MK0387 rpp30; Ribonuclease P subunit Rpp30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D MK0036 Small, Ras-like GTPase K03595 era; GTPase
D MK0164 Small, Ras-like GTPase K03595 era; GTPase
D MK0516 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D MK1364 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D MK0152 grs1; Glycyl-tRNA synthetase, class II K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D MK0758 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D MK0238 gatA; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D MK0960 gatB; Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D MK0359 gatC; Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D MK0240 ATPase involved in chromosome partitioning K03593 mrp; ATP-binding protein involved in chromosome partitioning
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:mka02000]
D MK1521 ABC-type molybdate transport system, periplasmic component K02020 modA; molybdate transport system substrate-binding protein
D MK1522 ABC-type molybdate transport systems, permease component K02018 modB; molybdate transport system permease protein
D MK1523 ABC-type molibdate transport systems, ATPase component K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5]
D MK0601 Homolog of ABC-type nitrate/sulfonate/taurine/bicarbonate transport systems, periplasmic component K15553 ssuA; sulfonate transport system substrate-binding protein
D MK0602 Homolog of ABC-type nitrate/sulfonate/taurine/bicarbonate transport systems, permease component K15554 ssuC; sulfonate transport system permease protein
D MK0603 Homolog of ABC-type nitrate/sulfonate/taurine/bicarbonate transport systems, ATPase component K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D MK1690 pstS; ABC-type phosphate transport system, periplasmic component K02040 pstS; phosphate transport system substrate-binding protein
D MK1688 pstA; ABC-type phosphate transport system, permease component K02037 pstC; phosphate transport system permease protein
D MK1687 pstB; ABC-type phosphate transport system, ATPase component K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D MK0181 cbiQ; ABC-type cobalt transport system, permease component K02008 cbiQ; cobalt/nickel transport system permease protein
D MK0180 cbiM; Cobalamin biosynthesis protein CbiM K02007 cbiM; cobalt/nickel transport system permease protein
D MK0182 cbiO; ABC-type cobalt transport system, ATPase component K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D MK0943 ABC-type multidrug transport system, permease subunit K01992 ABC-2.P; ABC-2 type transport system permease protein
D MK1322 Predicted membrane protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D MK0944 ABC-type multidrug transport system, ATPase subunit K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D MK1655 Permease subunit of a ABC-type transport system involved in lipoprotein release K02004 ABC.CD.P; putative ABC transport system permease protein
D MK1654 ATPase subunit of a ABC-type transport system involved in lipoprotein release K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D MK1233 sufC; ATPase subunit of an iron-regulated ABC-type transporter K09013 sufC; Fe-S cluster assembly ATP-binding protein
D MK0606 kch_1; Kef-type K+ transport systems, predicted NAD-binding component fused to an uncharacterized conserved domain K10716 kch; voltage-gated potassium channel
D MK1412 kch_2; NAD-binding subunit of the Kef-type K+ transport systems K10716 kch; voltage-gated potassium channel
D MK1549 kch_3; NAD-binding domain of the Kef-type K+ transport system fused to a uncharacterized conserved domain K10716 kch; voltage-gated potassium channel
D MK0053 amtB; Ammonia permease K03320 amt; ammonium transporter, Amt family
D MK0815 mscS; Small-conductance mechanosensitive channel K22044 ybiO; moderate conductance mechanosensitive channel
D MK0883 Permease related to cation transporters K07244 K07244; mgtE-like transporter
D MK0882 Permease related to cation transporters K07244 K07244; mgtE-like transporter
D MK1211 crcB; Integral membrane protein possibly involved in chromosome condensation K06199 crcB; fluoride exporter
D MK0670 Predicted NADH-flavin reductase K08978 TC.BAT1; bacterial/archaeal transporter family protein
D MK0951 ecm27_2; Ca2+/Na+ antiporter K07301 yrbG; cation:H+ antiporter
D MK0404 ecm27_1; Ca2+/Na+ antiporter K07301 yrbG; cation:H+ antiporter
D MK0552 nhaP; NhaP-type Na+/H+ or K+/H+ antiporter K11105 cvrA; potassium/hydrogen antiporter
D MK1010 trkG; Membrane subunit of a Trk-type K+ transport system K03498 trkH; trk/ktr system potassium uptake protein
D MK1011 trkA; NAD-binding component of a K+ transport system K03499 trkA; trk/ktr system potassium uptake protein
D MK0872 eriC; Chloride channel protein EriC K03281 clcA; chloride channel protein, CIC family
D MK1680 arsA; Arsenite transporting ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D MK1560 Predicted permease K24180 mleP; malate permease and related proteins
D MK1198 Integral membrane protein of the MarC family K05595 marC; multiple antibiotic resistance protein
D MK1247 feoA; Ferrous ion uptake system subunit K04758 feoA; ferrous iron transport protein A
D MK1248 feoB; Ferrous ion uptake system subunit, predicted GTPase K04759 feoB; ferrous iron transport protein B
C 02044 Secretion system [BR:mka02044]
D MK0707 Predicted ATPase involved in pili and flagella biosynthesis, VirB11 family K07332 flaI; archaeal flagellar protein FlaI
D MK0706 Predicted membrane protein K07333 flaJ; archaeal flagellar protein FlaJ
D MK1009 secD; Preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D MK1008 secF; Preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D MK0026 secY; Preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D MK1612 ffh; Signal recognition particle GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D MK1613 ftsY; Signal recognition particle GTPase K03110 ftsY; fused signal recognition particle receptor
D MK0822 sss1; Protein translocase subunit Sss1 K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D MK1551 sec65; 19 kDa subunit of the signal recognition particle K03105 SRP19; signal recognition particle subunit SRP19
D MK1201 tatA; Sec-independent protein secretion pathway component K03116 tatA; sec-independent protein translocase protein TatA
C 02042 Bacterial toxins
C 02022 Two-component system
C 02035 Bacterial motility proteins [BR:mka02035]
D MK0707 Predicted ATPase involved in pili and flagella biosynthesis, VirB11 family K07332 flaI; archaeal flagellar protein FlaI
D MK0706 Predicted membrane protein K07333 flaJ; archaeal flagellar protein FlaJ
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:mka04812]
D MK0963 Predicted dioxygenase K06990 MEMO1; MEMO1 family protein
D MK0168 mreB; HSP70 class molecular chaperones involved in cell morphogenesis K03569 mreB; rod shape-determining protein MreB and related proteins
D MK0821 ftsZ_1; FtsZ GTPase involved in cell division K03531 ftsZ; cell division protein FtsZ
D MK0218 ATPase involved in chromosome partitioning K03609 minD; septum site-determining protein MinD
C 04147 Exosome [BR:mka04147]
D MK1647 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D MK1662 pgk; 3-phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D MK0247 GTPase, translation elongation factor K03231 EEF1A; elongation factor 1-alpha
D MK0679 fusA; Translation elongation and release factor (GTPase), contains an intein K03234 EEF2; elongation factor 2
D MK0566 exo; 5'-3' exonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D MK1600 guaB; IMP dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D MK1455 rps31; Ribosomal protein S27AE K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D MK1378 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D MK0025 adkA; Archaeal adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D MK0610 Adenine/guanine phosphoribosyltransferase homolog K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D MK0622 argH; Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D MK0942 argG; Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D MK0338 glnA; Glutamine synthase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D MK0198 hemB; Delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D MK0297 Predicted dehydrogenase related to phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D MK0319 Predicted dehydrogenase related to phosphoglycerate dehydrogenase, a fragment K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D MK0320 serA; Predicted dehydrogenase related to phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D MK0849 lpd; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D MK1664 tpiA; Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 02048 Prokaryotic defense system [BR:mka02048]
D MK1312 Uncharacterized conserved protein K15342 cas1; CRISP-associated protein Cas1
D MK1310 Uncharacterized conserved protein K09951 cas2; CRISPR-associated protein Cas2
D MK1314 Predicted DNA-dependent DNA polymerase, component of a thermophile-specific DNA repair system K07016 csm1; CRISPR-associated protein Csm1
D MK1315 Uncharacterized conserved protein K19138 csm2; CRISPR-associated protein Csm2
D MK1316 Predicted component of a thermophile-specific DNA repair system, contains a RAMP domain K09002 csm3; CRISPR-associated protein Csm3
D MK1319 Predicted component of a thermophile-specific DNA repair system, contains a RAMP domain K19140 csm5; CRISPR-associated protein Csm5
D MK1297 Predicted DNA-dependent DNA polymerase, component of a thermophile-specific DNA repair system K19076 cmr2; CRISPR-associated protein Cmr2
D MK1299 Predicted component of a thermophile-specific DNA repair system, contains a RAMP domain K09000 cmr4; CRISPR-associated protein Cmr4
D MK1296 Predicted component of a thermophile-specific DNA repair system, contains two domains of the RAMP family K19142 cmr6; CRISPR-associated protein Cmr6
D MK1520 dcm; Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D MK0821 ftsZ_1; FtsZ GTPase involved in cell division K03531 ftsZ; cell division protein FtsZ
D MK0168 mreB; HSP70 class molecular chaperones involved in cell morphogenesis K03569 mreB; rod shape-determining protein MreB and related proteins
D MK0757 glnS; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D MK0744 Predicted nuclei-acid-binding protein, consists of a PIN domain and a Zn-ribbon K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules
C 01504 Antimicrobial resistance genes
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:mka03100]
D MKt02 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D MKt12 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D MKt13 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D MKt23 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D MKt34 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D MKt22 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D MKt18 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D MKt25 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D MKt06 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D MKt26 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D MKt33 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D MKt01 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D MKt30 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D MKt21 tRNA-His K14226 tRNA-His; tRNA His
D MKt03 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D MKt14 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D MKt17 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D MKt19 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D MKt20 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D MKt10 tRNA-Met K14230 tRNA-Met; tRNA Met
D MKt05 tRNA-Met K14230 tRNA-Met; tRNA Met
D MKt11 tRNA-Met K14230 tRNA-Met; tRNA Met
D MKt31 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D MKt27 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D MKt32 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D MKt15 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D MKt28 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D MKt35 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D MKt08 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D MKt24 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D MKt04 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D MKt29 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D MKt16 tRNA-Val K14237 tRNA-Val; tRNA Val
D MKt09 tRNA-Val K14237 tRNA-Val; tRNA Val
D MKr02 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D MKr03 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D MKr01 5S ribisomal RNA K01985 5SrRNA; 5S ribosomal RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D MK0248 Predicted dehydrogenase K18855 E1.1.1.374; UDP-N-acetylglucosamine 3-dehydrogenase [EC:1.1.1.374]
D MK0233 Predicted dinucleotide-binding enzyme K06988 fno; 8-hydroxy-5-deazaflavin:NADPH oxidoreductase [EC:1.5.1.40]
D MK0881 NAD(FAD)-dependent dehydrogenase K17870 nox1; NADH oxidase (H2O2-forming) [EC:1.6.3.3]
D MK0799 Coenzyme F420-reducing hydrogenase, beta subunit fused to oxidoreductase related to nitrite reductase K21816 fsr; sulfite reductase (coenzyme F420) [EC:1.8.98.3]
D MK1074 Predicted Fe-S oxidoreductase K06937 E1.21.98.5; tetraether lipid synthase [EC:1.21.98.5]
D MK0952 Pyruvate-formate lyase-activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D MK0187 Pyruvate-formate lyase-activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D MK0286 Pyruvate-formate lyase-activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D MK1086 Ferredoxin domain fused to pyruvate-formate lyase-activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D MK0047 Pyruvate-formate lyase-activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D MK1027 Pyruvate-formate lyase-activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D MK0928 pflX; Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating protein K04070 pflX; putative pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D MK0282 pcm; Protein-L-isoaspartate carboxylmethyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D MK0747 dph5; Methyltransferase involved in diphthamide biosynthesis K20215 dph5; diphthine synthase [EC:2.1.1.98]
D MK0650 Fe-S oxidoreductase, related to NifB/MoaA family K25222 mmp10; [methyl coenzyme M reductase]-L-arginine C-5-methyltransferase [EC:2.1.1.379]
D MK0534 Uncharacterized protein conserved in archaea K22882 K22882; thymidylate synthase [EC:2.1.1.-]
D MK0097 Predicted carbamoyl transferase, NodU family K00612 nodU; carbamoyltransferase [EC:2.1.3.-]
D MK0737 dys1; Deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46]
D MK0675 NCAIR mutase K06898 larB; pyridinium-3,5-biscarboxylic acid mononucleotide synthase [EC:2.5.1.143]
D MK1084 Queuine tRNA-ribosyltransferase, contains RNA-binding PUA domain K07557 tgtA2; archaeosine synthase alpha-subunit [EC:2.6.1.97 2.6.1.-]
D MK0340 Predicted Fe-S oxidoreductase K06936 raSEA; archaeosine synthase beta-subunit [EC:2.6.1.-]
D MK0868 2-Phosphoglycerate kinase K05715 2PGK; 2-phosphoglycerate kinase [EC:2.7.2.16]
D MK1507 Uncharacterized conserved protein K18672 dacA; diadenylate cyclase [EC:2.7.7.85]
D MK0950 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 K23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106]
D MK0812 Uncharacterized conserved protein K09116 K09116; damage-control phosphatase, subfamily I [EC:3.1.3.-]
D MK0546 tatD; Mg-dependent DNase K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D MK1164 Predicted nuclease of the micrococcal nuclease (thermonuclease) family K01174 nuc; micrococcal nuclease [EC:3.1.31.1]
D MK0507 Predicted nuclease of the RecB family K07503 nucS; endonuclease [EC:3.1.-.-]
D MK0807 Uncharacterized conserved protein K22205 E3.13.2.3; S-adenosyl-L-methionine hydrolase (adenosine-forming) [EC:3.13.2.3]
D MK0808 Short chain dehydrogenase fused to sugar kinase K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D MK0541 Uncharacterized protein conserved in archaea K01741 E4.2.99.18; DNA-(apurinic or apyrimidinic site) lyase [EC:4.2.99.18]
D MK0071 ATP-utilizing enzymes of the PP-loop superfamily K06864 larE; pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase [EC:4.4.1.37]
D MK1105 Uncharacterized conserved protein K09121 larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12]
D MK0260 Activator of 2-hydroxyglutaryl-CoA dehydratase, contains a HSP70-class ATPase domain K23876 hgdC; (R)-2-hydroxyacyl-CoA dehydratese activating ATPase [EC:5.6.1.9]
D MK0115 Uncharacterized conserved protein K24409 ycaO; thioglycine synthase [EC:6.2.2.1]
D MK0001 rcl1; RNA phosphate cyclase K18105 rtcA; RNA 3'-terminal phosphate cyclase (GTP) [EC:6.5.1.5]
D MK0505 Cyclic 2,3-diphosphoglycerate-synthetase K05716 CPGS; cyclic 2,3-diphosphoglycerate synthase [EC:6.5.1.9]
D MK0528 ATP-dependent DNA ligase, homolog of eukaryotic ligase III K07468 K07468; DNA/RNA ligase [EC:6.5.1.-]
D MK0460 ehaP; Ferredoxin K03616 rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2]
C 99981 Carbohydrate metabolism
C 99982 Energy metabolism
D MK0532 Rubrerythrin K19824 fprB; rubrerythrin
D MK1249 Rubrerythrin K19824 fprB; rubrerythrin
D MK0582 Predicted Fe-S oxidoreductase K02585 nifB; nitrogen fixation protein NifB
D MK0477 ehaA; Uncharacterized membrane protein, conserved in archaea K14092 ehaA; energy-converting hydrogenase A subunit A
D MK0476 ehaB; Uncharacterized membrane protein, conserved in archaea K14093 ehaB; energy-converting hydrogenase A subunit B
D MK0475 ehaC; Uncharacterized membrane protein, conserved in archaea K14094 ehaC; energy-converting hydrogenase A subunit C
D MK0474 ehaD; Uncharacterized membrane protein, conserved in archaea K14095 ehaD; energy-converting hydrogenase A subunit D
D MK0473 ehaE; Uncharacterized membrane protein, conserved in archaea K14096 ehaE; energy-converting hydrogenase A subunit E
D MK0472 ehaF; Uncharacterized membrane protein, conserved in archaea K14097 ehaF; energy-converting hydrogenase A subunit F
D MK0471 ehaG; Uncharacterized membrane protein, conserved in archaea K14098 ehaG; energy-converting hydrogenase A subunit G
D MK0470 ehaH; Uncharacterized membrane protein, conserved in archaea K14099 ehaH; energy-converting hydrogenase A subunit H
D MK0468 ehaJ; Membrane protein related to formate hydrogenlyase subunit 4 K14101 ehaJ; energy-converting hydrogenase A subunit J
D MK0466 ehaL; Uncharacterized membrane protein, conserved in archaea K14103 ehaL; energy-converting hydrogenase A subunit L
D MK0465 ehaM; Uncharacterized protein conserved in archaea K14104 ehaM; energy-converting hydrogenase A subunit M
D MK0464 ehaN; Ni,Fe-hydrogenase III small subunit K14105 ehaN; energy-converting hydrogenase A subunit N
D MK0463 ehaO; Ni,Fe-hydrogenase III large subunit K14106 ehaO; energy-converting hydrogenase A subunit O
D MK0462 ehaQ; Ferredoxin K14107 ehaP; energy-converting hydrogenase A subunit P
D MK0461 ehbK; Ferredoxin K14108 ehaQ; energy-converting hydrogenase A subunit Q
D MK0346 Uncharacterized protein conserved in archaea K14109 ehaR; energy-converting hydrogenase A subunit R
D MK0609 Predicted metabolic regulator containing the ACT domain K06862 ehbQ; energy-converting hydrogenase B subunit Q
D MK1183 Polyferredoxin K02574 napH; ferredoxin-type protein NapH
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
C 99986 Glycan metabolism
D MK0770 Predicted integral membrane protein K07027 K07027; glycosyltransferase 2 family protein
D MK1387 Predicted integral membrane protein K07027 K07027; glycosyltransferase 2 family protein
C 99987 Cofactor metabolism
D MK1080 mobB; Molybdopterin-guanine dinucleotide biosynthesis protein K03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein
C 99988 Secondary metabolism
C 99999 Others
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D MK0449 Predicted transcription factor, homolog of eukaryotic MBF1 K03627 MBF1; putative transcription factor
D MK0715 ssh10b_1; Archaea-specific DNA-binding protein K03622 ssh10b; archaea-specific DNA-binding protein
D MK1089 ssh10b_2; Archaea-specific DNA-binding protein K03622 ssh10b; archaea-specific DNA-binding protein
D MK0220 lsm1; Small nuclear ribonucleoprotein (snRNP) homolog K04796 RUXX; small nuclear ribonucleoprotein
D MK0885 Predicted transcriptional regulator consisting of an HTH domain fused to a Zn-ribbon K07743 K07743; transcriptional regulator
D MK0231 Predicted transcriptional regulator K07745 K07745; transcriptional regulator
C 99974 Translation
D MK1658 Predicted RNA-binding protein K07572 K07572; putative nucleotide binding protein
D MK1274 Predicted hydrolase of the metallo-beta-lactamase superfamily K07577 K07577; putative mRNA 3-end processing factor
D MK1258 Predicted hydrolase of the metallo-beta-lactamase superfamily fused to a uncharacterized domain K07577 K07577; putative mRNA 3-end processing factor
D MK0062 Predicted RNA methylase K07579 K07579; putative methylase
D MK0256 Predicted Zn-ribbon-containing RNA-binding protein with a function in translation K07580 K07580; Zn-ribbon RNA-binding protein
D MK0388 Predicted exosome subunit K07581 K07581; RNA-binding protein
C 99975 Protein processing
D MK0227 hypC; Hydrogenase maturation factor K04653 hypC; hydrogenase expression/formation protein HypC
D MK0226 hypD; Hydrogenase maturation factor K04654 hypD; hydrogenase expression/formation protein HypD
D MK1544 hypE_2; Hydrogenase maturation factor K04655 hypE; hydrogenase expression/formation protein HypE
D MK0648 hypF; Hydrogenase maturation factor K04656 hypF; hydrogenase maturation protein HypF
D MK1493 hypE_1; Hydrogenase maturation factor K07388 K07388; hydrogenase expression/formation protein
D MK1368 Predicted ATPase of the AAA+ class K07392 PRS2; AAA family ATPase
D MK0956 Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit K07398 K07398; conserved protein with predicted RNA binding PUA domain
C 99976 Replication and repair
D MK1259 Predicted DNA methylase containing a Zn-ribbon module K07445 K07445; putative DNA methylase
D MK0157 Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain K07463 K07463; archaea-specific RecJ-like exonuclease
D MK0007 tip49; DNA helicase TIP49, TBP-interacting protein K07472 TIP49; TBP-interacting protein
D MK0443 Predicted RNA-binding protein of the translin family K07477 K07477; translin
D MK0605 Predicted transposase K07496 K07496; putative transposase
C 99979 Viral proteins
C 99998 Others
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D MK1576 Amino acid transporter K03294 TC.APA; basic amino acid/polyamine antiporter, APA family
D MK0561 pitA; Phosphate permease K03306 TC.PIT; inorganic phosphate transporter, PiT family
C 99978 Cell growth
D MK0726 cooC_2; CO dehydrogenase maturation factor K07321 cooC; CO dehydrogenase maturation factor
D MK0721 cooC_1; CO dehydrogenase maturation factor K07321 cooC; CO dehydrogenase maturation factor
D MK0438 Uncharacterized membrane protein K06384 spoIIM; stage II sporulation protein M
C 99993 Cell motility
C 99995 Signaling proteins
D MK1213 Predicted metabolic regulator containing an ACT domain K07166 K07166; ACT domain-containing protein
D MK1619 DNA-binding protein K06875 PDCD5; programmed cell death protein 5
C 99992 Structural proteins
C 99994 Others
D MK0862 phoU; Phosphate uptake regulator K02039 phoU; phosphate transport system protein
D MK1492 cutA; Uncharacterized protein implicated in tolerance to divalent cations K03926 cutA; periplasmic divalent cation tolerance protein
B
B 09194 Poorly characterized
C 99996 General function prediction only
D MK0169 Predicted phosphatase of the PHP family K04477 ycdX; putative hydrolase
D MK1536 P-loop ATPase of the PilT family K06865 K06865; ATPase
D MK0032 C4-type Zn-finger-containing protein K06874 K06874; zinc finger protein
D MK0244 Distinct Superfamily II helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 K06877; DEAD/DEAH box helicase domain-containing protein
D MK0970 Predicted hydrolase of the HAD superfamily K07025 K07025; putative hydrolase of the HAD superfamily
D MK1171 Predicted membrane-bound metal-dependent hydrolase K07038 K07038; inner membrane protein
D MK1334 Predicted membrane-bound metal-dependent hydrolase K07038 K07038; inner membrane protein
D MK0074 Predicted metal-dependent hydrolase of the urease superfamily K07049 K07049; TatD-related deoxyribonuclease
D MK1588 Uncharacterized Zn-finger-containing protein K07143 K07143; UPF0148 protein
D MK0890 Predicted membrane protein K08971 K08971; putative membrane protein
D MK0976 Predicted membrane protein K08979 K08979; putative membrane protein
C 99997 Function unknown
D MK0996 Archaea-specific enzyme of the ATP-grasp superfamily K06869 K06869; uncharacterized protein
D MK0194 HD superfamily phosphohydrolase K06885 K06885; uncharacterized protein
D MK1589 Predicted ATP-dependent carboligase related to biotin carboxylase K06913 K06913; uncharacterized protein
D MK0347 Predicted ABC-type ATPase K06924 K06924; uncharacterized protein
D MK0612 Predicted DNA-binding protein containing a PD1-like DNA-binding motif K06934 K06934; uncharacterized protein
D MK0989 Predicted Fe-S oxidoreductase K06935 K06935; uncharacterized protein
D MK0811 Predicted Fe-S protein K06939 K06939; uncharacterized protein
D MK1372 Small, Ras-like GTPase K06945 K06945; uncharacterized protein
D MK0254 Predicted HD superfamily hydrolase K06950 K06950; uncharacterized protein
D MK0494 Predicted HD superfamily hydrolase K06950 K06950; uncharacterized protein
D MK1470 Predicted HD superfamily hydrolase K06950 K06950; uncharacterized protein
D MK1388 Predicted calcineurin superfamily phosphoesterase K06953 K06953; uncharacterized protein
D MK1463 Predicted TIM-barrel enzyme K06971 K06971; uncharacterized protein
D MK0595 Predicted archaea-specific methyltransferase K06983 K06983; uncharacterized protein
D MK1596 Metal-dependent hydrolase of the aminoacylase-2/carboxypeptidase Z family K06987 K06987; uncharacterized protein
D MK1056 Predicted exporter of the RND superfamily K07003 K07003; uncharacterized protein
D MK0629 Predicted metabolic regulator containing V4R domain K07013 K07013; uncharacterized protein
D MK0630 Predicted metabolic regulator containing V4R domain K07013 K07013; uncharacterized protein
D MK0785 Predicted metabolic regulator containing V4R domain K07013 K07013; uncharacterized protein
D MK1078 Predicted metabolic regulator containing V4R domain K07013 K07013; uncharacterized protein
D MK1107 Predicted metabolic regulator containing two V4R domains K07013 K07013; uncharacterized protein
D MK0632 Predicted metabolic regulator containing two V4R domains K07013 K07013; uncharacterized protein
D MK0542 Predicted transcriptional regulator consisting of a V4R domain and a DNA-binding HTH domain K07013 K07013; uncharacterized protein
D MK1511 Predicted metabolic regulator containing V4R domain K07013 K07013; uncharacterized protein
D MK0213 Predicted hydrolase of the metallo-beta-lactamase superfamily K07022 K07022; uncharacterized protein
D MK1232 sufB; Membrane subunit of an iron-regulated ABC-type transporter K07033 K07033; uncharacterized protein
D MK1227 Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain K07041 K07041; uncharacterized protein
D MK0426 Uncharacterized protein K07045 K07045; uncharacterized protein
D MK0232 Predicted metal-dependent hydrolase of the TIM-barrel fold K07051 K07051; uncharacterized protein
D MK0533 Predicted metal-dependent hydrolase of the TIM-barrel fold K07051 K07051; uncharacterized protein
D MK1377 Predicted nucleic-acid-binding protein containing a Zn-ribbon K07068 K07068; uncharacterized protein
D MK0982 Predicted nucleotidyltransferase of the DNA polymerase beta superfamily K07073 K07073; uncharacterized protein
D MK1464 Predicted nucleotidyltransferase of the DNA polymerase beta superfamily K07073 K07073; uncharacterized protein
D MK1407 Predicted permease K07089 K07089; uncharacterized protein
D MK0141 Predicted permease K07090 K07090; uncharacterized protein
D MK0143 Predicted permease K07090 K07090; uncharacterized protein
D MK0357 Peroxiredoxin, predicted regulator of disulfide bond formation K07092 K07092; uncharacterized protein
D MK0092 Predicted phosphoesterase K07095 K07095; uncharacterized protein
D MK0768 Predicted phosphoesterase K07095 K07095; uncharacterized protein
D MK1469 Cacineurin superfamily phosphoesterase K07096 K07096; uncharacterized protein
D MK0033 2-Phosphoglycerate kinase fused to conserved uncharacterized domain K07105 K07105; uncharacterized protein
D MK0262 Predicted transporter component K07112 K07112; uncharacterized protein
D MK0795 Selenophosphate synthetase K07123 K07123; uncharacterized protein
D MK0889 Predicted enzyme related to selenophosphate synthetase K07123 K07123; uncharacterized protein
D MK1558 Selenophosphate synthetase-related enzyme K07123 K07123; uncharacterized protein
D MK0520 Uncharacterized ABC-type transporter, duplicated ATPase domains K07128 K07128; uncharacterized protein
D MK0987 Fe-S protein related to pyruvate formate-lyase activating enzyme K07129 K07129; uncharacterized protein
D MK0216 Predicted regulator of Ras-like GTPase activity, member of the Roadblock/LC7/MglB family K07131 K07131; uncharacterized protein
D MK1325 Predicted regulator of Ras-like GTPase activity, member of the Roadblock/LC7/MglB family K07131 K07131; uncharacterized protein
D MK1505 Predicted ATPase of the PP-loop superfamily K07134 K07134; uncharacterized protein
D MK0983 Predicted archaea-specific RNA-binding protein containing a C-terminal EMAP domain K07135 K07135; uncharacterized protein
D MK0501 Uncharacterized FAD-dependent dehydrogenase K07137 K07137; uncharacterized protein
D MK0044 Uncharacterized Fe-S oxidoreductase K07139 K07139; uncharacterized protein
D MK1448 Predicted RNA-binding protein containing PIN domain K07158 K07158; uncharacterized protein
D MK0421 Uncharacterized enzyme of the ATP-grasp superfamily K07159 K07159; uncharacterized protein
D MK0522 Zn-finger-containing protein K07162 K07162; uncharacterized protein
D MK0166 Zn-ribbon-containing protein K07163 K07163; uncharacterized protein
D MK0401 Uncharacterized conserved protein K09003 K09003; uncharacterized protein
D MK1506 Uncharacterized conserved protein K09005 K09005; uncharacterized protein
D MK0041 Uncharacterized conserved protein K09010 K09010; uncharacterized protein
D MK0057 Uncharacterized conserved protein K09120 K09120; uncharacterized protein
D MK0487 Uncharacterized conserved protein K09122 K09122; uncharacterized protein
D MK0273 Uncharacterized conserved protein K09131 K09131; uncharacterized protein
D MK0997 Uncharacterized conserved protein K09135 K09135; uncharacterized protein
D MK1210 Uncharacterized conserved protein K09137 K09137; uncharacterized protein
D MK0131 Uncharacterized conserved protein K09139 K09139; uncharacterized protein
D MK0488 Uncharacterized conserved protein K09141 K09141; uncharacterized protein
D MK0145 Uncharacterized conserved protein K09147 K09147; uncharacterized protein
D MK0968 Uncharacterized conserved protein K09148 K09148; uncharacterized protein
D MK0407 Uncharacterized protein conserved in archaea K09150 K09150; uncharacterized protein
D MK0034 Uncharacterized conserved protein K09152 K09152; uncharacterized protein
D MK0195 Uncharacterized conserved protein K09154 K09154; uncharacterized protein
D MK1214 Uncharacterized conserved protein K09157 K09157; uncharacterized protein
D MK0350 Uncharacterized protein conserved in archaea K09715 K09715; uncharacterized protein
D MK0611 Uncharacterized protein conserved in archaea K09717 K09717; uncharacterized protein
D MK0624 Uncharacterized protein conserved in archaea K09718 K09718; uncharacterized protein
D MK0994 Uncharacterized protein conserved in archaea K09718 K09718; uncharacterized protein
D MK1586 Uncharacterized protein conserved in archaea K09721 K09721; uncharacterized protein
D MK0056 Uncharacterized protein conserved in archaea K09725 K09725; uncharacterized protein
D MK0454 Uncharacterized protein conserved in archaea K09727 K09727; uncharacterized protein
D MK1632 Uncharacterized protein conserved in archaea K09728 K09728; uncharacterized protein
D MK0748 Uncharacterized protein conserved in archaea K09731 K09731; uncharacterized protein
D MK1384 Uncharacterized protein conserved in archaea K09732 K09732; uncharacterized protein
D MK0399 Uncharacterized protein conserved in archaea K09736 K09736; uncharacterized protein
D MK1676 Uncharacterized protein conserved in archaea K09737 K09737; uncharacterized protein
D MK1657 Uncharacterized protein conserved in archaea K09738 K09738; uncharacterized protein
D MK0206 Uncharacterized protein conserved in archaea K09740 K09740; uncharacterized protein
D MK0059 Uncharacterized protein conserved in archaea K09742 K09742; uncharacterized protein
D MK0165 Uncharacterized protein conserved in archaea K09743 K09743; uncharacterized protein
D MK0966 Uncharacterized protein conserved in archaea K09746 K09746; uncharacterized protein
!
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#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: May 11, 2024