+C Lipid biosynthesis protein KO
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Lipid Biosynthesis Proteins - Mus musculus (house mouse)
%
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AFatty acid synthase
B Animal type
C 14104 Fasn; fatty acid synthase K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
B Yeast type
B Bacteria type
B Component type
C 223722 Mcat; malonyl CoA:ACP acyltransferase (mitochondrial) K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
C 71147 Oxsm; 3-oxoacyl-ACP synthase, mitochondrial K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
C 56348 Hsd17b12; hydroxysteroid (17-beta) dehydrogenase 12 K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
C 70757 Hacd2; 3-hydroxyacyl-CoA dehydratase 2 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
C 30963 Hacd1; 3-hydroxyacyl-CoA dehydratase 1 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
C 66775 Hacd4; 3-hydroxyacyl-CoA dehydratase 4 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
C 57874 Hacd3; 3-hydroxyacyl-CoA dehydratase 3 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
C 111175 Pecr; peroxisomal trans-2-enoyl-CoA reductase K07753 PECR; peroxisomal trans-2-enoyl-CoA reductase [EC:1.3.1.38]
C 106529 Tecr; trans-2,3-enoyl-CoA reductase K10258 TER; very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
C 99035 Olah; oleoyl-ACP hydrolase K01071 MCH; medium-chain acyl-[acyl-carrier-protein] hydrolase [EC:3.1.2.21]
C 19063 Ppt1; palmitoyl-protein thioesterase 1 K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]
C 54397 Ppt2; palmitoyl-protein thioesterase 2 K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]
C 26897 Acot1; acyl-CoA thioesterase 1 K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
C 171210 Acot2; acyl-CoA thioesterase 2 K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
C 171281 Acot3; acyl-CoA thioesterase 3 K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
C 217698 Acot5; acyl-CoA thioesterase 5 K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
C 171282 Acot4; acyl-CoA thioesterase 4 K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
C 217700 Acot6; acyl-CoA thioesterase 6 K11993 ACOT6; acyl-CoA thioesterase 6 [EC:3.1.2.-]
C 70025 Acot7; acyl-CoA thioesterase 7 K17360 ACOT7; acyl-coenzyme A thioesterase 7 [EC:3.1.2.2]
C 56360 Acot9; acyl-CoA thioesterase 9 K17361 ACOT9; acyl-coenzyme A thioesterase 9 [EC:3.1.2.-]
C 64833 Acot10; acyl-CoA thioesterase 10 K17361 ACOT9; acyl-coenzyme A thioesterase 9 [EC:3.1.2.-]
C 329910 Acot11; acyl-CoA thioesterase 11 K12417 ACOT11; acyl-CoA thioesteraes 11 [EC:3.1.2.-]
C 66834 Acot13; acyl-CoA thioesterase 13 K17362 ACOT13; acyl-coenzyme A thioesterase 13 [EC:3.1.2.-]
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ADesaturase
B First
C 20249 Scd1; stearoyl-Coenzyme A desaturase 1 K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
C 20250 Scd2; stearoyl-Coenzyme A desaturase 2 K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
C 30049 Scd3; stearoyl-coenzyme A desaturase 3 K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
C 329065 Scd4; stearoyl-coenzyme A desaturase 4 K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
B Omega
C 60527 Fads3; fatty acid desaturase 3 K10225 FADS3; fatty acid desaturase 3 (Delta-13 desaturase) [EC:1.14.19.-]
B Front-end
C 76267 Fads1; fatty acid desaturase 1 K10224 FADS1; acyl-CoA (8-3)-desaturase (Delta-5 desaturase) [EC:1.14.19.44]
C 56473 Fads2; fatty acid desaturase 2 K10226 FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]
B Sphingolipid
C 70059 Degs2; delta 4-desaturase, sphingolipid 2 K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
C 13244 Degs1; delta 4-desaturase, sphingolipid 1 K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
C 619326 Degs1l; delta 4-desaturase, sphingolipid 1 like K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
B Other
C 328035 Fads6; fatty acid desaturase domain family, member 6 K12419 FADS6; fatty acid desaturase 6 [EC:1.14.19.-]
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AElongase
B LCFA
B PUFA
C 54325 Elovl1; ELOVL fatty acid elongase 1 K10247 ELOVL1; elongation of very long chain fatty acids protein 1 [EC:2.3.1.199]
C 54326 Elovl2; ELOVL fatty acid elongase 2 K10205 ELOVL2; elongation of very long chain fatty acids protein 2 [EC:2.3.1.199]
C 83603 Elovl4; ELOVL fatty acid elongase 4 K10249 ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]
C 68801 Elovl5; ELOVL fatty acid elongase 5 K10244 ELOVL5; elongation of very long chain fatty acids protein 5 [EC:2.3.1.199]
C 170439 Elovl6; ELOVL fatty acid elongase 6 K10203 ELOVL6; elongation of very long chain fatty acids protein 6 [EC:2.3.1.199]
C 74559 Elovl7; ELOVL fatty acid elongase 7 K10250 ELOVL7; elongation of very long chain fatty acids protein 7 [EC:2.3.1.199]
B Unclassified
C 12686 Elovl3; ELOVL fatty acid elongase 3 K10248 ELOVL3; elongation of very long chain fatty acids protein 3 [EC:2.3.1.199]
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APolyketide synthase
B Modular PKS
B Component type
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AAcyl-CoA synthetase
B Short/medium chain acyl-CoA synthetase
C 68738 Acss1; acyl-CoA synthetase short-chain family member 1 K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 60525 Acss2; acyl-CoA synthetase short-chain family member 2 K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 380660 Acss3; acyl-CoA synthetase short-chain family member 3 K01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17]
C 78894 Aacs; acetoacetyl-CoA synthetase K01907 AACS; acetoacetyl-CoA synthetase [EC:6.2.1.16]
C 117147 Acsm1; acyl-CoA synthetase medium-chain family member 1 K23756 ACSM1; medium-chain acyl-CoA ligase / lipoate-activating enzyme [EC:6.2.1.2]
C 233799 Acsm2; acyl-CoA synthetase medium-chain family member 2 K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
C 233801 Acsm4; acyl-CoA synthetase medium-chain family member 4 K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
C 272428 Acsm5; acyl-CoA synthetase medium-chain family member 5 K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
C 20216 Acsm3; acyl-CoA synthetase medium-chain family member 3 K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
C 264895 Acsf2; acyl-CoA synthetase family member 2 K23617 ACSF2; medium-chain acyl-CoA ligase, mitochondrial [EC:6.2.1.2]
B Long/very long chain acyl-CoA synthetase
C 14081 Acsl1; acyl-CoA synthetase long-chain family member 1 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 50790 Acsl4; acyl-CoA synthetase long-chain family member 4 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 216739 Acsl6; acyl-CoA synthetase long-chain family member 6 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 74205 Acsl3; acyl-CoA synthetase long-chain family member 3 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 433256 Acsl5; acyl-CoA synthetase long-chain family member 5 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 328845 Acsbg2; acyl-CoA synthetase bubblegum family member 2 K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
C 94180 Acsbg1; acyl-CoA synthetase bubblegum family member 1 K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
C 78625 Acsbg3; acyl-CoA synthetase bubblegum family member 3 K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
C 26457 Slc27a1; solute carrier family 27 (fatty acid transporter), member 1 K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
C 26569 Slc27a4; solute carrier family 27 (fatty acid transporter), member 4 K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
C 26458 Slc27a2; solute carrier family 27 (fatty acid transporter), member 2 K08746 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
C 26568 Slc27a3; solute carrier family 27 (fatty acid transporter), member 3 K08772 SLC27A3; solute carrier family 27 (fatty acid transporter), member 3 [EC:6.2.1.-]
B Unknown
C 231326 Aasdh; aminoadipate-semialdehyde dehydrogenase K00142 AASDH; acyl-CoA synthetase [EC:6.2.1.-]
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APhospholipid acyltransferase
B GPAT
C 14732 Gpam; glycerol-3-phosphate acyltransferase, mitochondrial K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15]
C 215456 Gpat2; glycerol-3-phosphate acyltransferase 2, mitochondrial K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15]
C 102247 Gpat4; glycerol-3-phosphate acyltransferase 4 K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15]
C 231510 Gpat3; glycerol-3-phosphate acyltransferase 3 K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15]
B LPAAT/LPLAT
C 55979 Agpat1; 1-acylglycerol-3-phosphate O-acyltransferase 1 K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
C 67512 Agpat2; 1-acylglycerol-3-phosphate O-acyltransferase 2 K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
C 67469 Abhd5; abhydrolase domain containing 5 K13699 ABHD5; abhydrolase domain-containing protein 5 [EC:2.3.1.51]
C 225010 Lclat1; lysocardiolipin acyltransferase 1 K13513 LCLAT1; lysocardiolipin and lysophospholipid acyltransferase [EC:2.3.1.- 2.3.1.51]
C 66826 Tafazzin; tafazzin, phospholipid-lysophospholipid transacylase K13511 TAZ; monolysocardiolipin acyltransferase [EC:2.3.1.-]
C 218121 Mboat1; membrane bound O-acyltransferase domain containing 1 K13517 MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]
C 67216 Mboat2; membrane bound O-acyltransferase domain containing 2 K13517 MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]
C 28169 Agpat3; 1-acylglycerol-3-phosphate O-acyltransferase 3 K13523 AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
C 68262 Agpat4; 1-acylglycerol-3-phosphate O-acyltransferase 4 K13523 AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
C 270084 Lpcat2; lysophosphatidylcholine acyltransferase 2 K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
C 210992 Lpcat1; lysophosphatidylcholine acyltransferase 1 K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
C 70902 Lpcat2b; lysophosphatidylcholine acyltransferase 2B K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
C 99010 Lpcat4; lysophosphatidylcholine acyltransferase 4 K13512 LPCAT4; lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-]
C 226856 Lpgat1; lysophosphatidylglycerol acyltransferase 1 K13514 LPGAT1; lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-]
C 14792 Lpcat3; lysophosphatidylcholine acyltransferase 3 K13515 LPCAT3; lysophospholipid acyltransferase 5 [EC:2.3.1.23 2.3.1.-]
C 77582 Mboat7; membrane bound O-acyltransferase domain containing 7 K13516 MBOAT7; lysophospholipid acyltransferase 7 [EC:2.3.1.-]
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AOthers
B Multifunctional type
B Component type
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#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: November 27, 2023
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Desaturase/elongase family classification based on Hashimoto et al. (2008)