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Transcription Machinery - Ornithorhynchus anatinus (platypus)
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AEukaryotic type
B RNA polymerase II system
C RNA polymerase II
D Core subunits
E 100086954 POLR2A; DNA-directed RNA polymerase II subunit RPB1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
E 100092521 POLR2B; DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
E 100080697 POLR2C; DNA-directed RNA polymerase II subunit RPB3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
E 100083768 POLR2J; DNA-directed RNA polymerase II subunit RPB11-a K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
D Pol II specific subunits
E 100087858 POLR2D; DNA-directed RNA polymerase II subunit RPB4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
E 100082492 POLR2G; DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 114812179 POLR2I; DNA-directed RNA polymerase II subunit RPB9 isoform X2 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
D Pol I, II, III common subunits
E 100090631 POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
E 100089660 POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
E 100074090 POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E 114810046 POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
D Pol IV and V specific subunits
C Basal transcription factors
D TFIIA
E 100091922 GTF2A1; transcription initiation factor IIA subunit 1 isoform X1 K03122 TFIIA1; transcription initiation factor TFIIA large subunit
E 100078479 GTF2A2; transcription initiation factor IIA subunit 2 K03123 TFIIA2; transcription initiation factor TFIIA small subunit
D TFIIB
E 100076897 GTF2B; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D TFIID
E 100082878 TBPL2; TATA box-binding protein-like 2 isoform X1 K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
E 100075429 TBPL1; TATA box-binding protein-like 1 K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
E 100091633 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
E 100087158 transcription initiation factor TFIID subunit 1 K03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
E 103166278 TAF1; transcription initiation factor TFIID subunit 1 isoform X1 K03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
E 100078775 TAF2; transcription initiation factor TFIID subunit 2 K03128 TAF2; transcription initiation factor TFIID subunit 2
E 100085662 TAF3; transcription initiation factor TFIID subunit 3 K14650 TAF3; transcription initiation factor TFIID subunit 3
E 100074124 TAF4; transcription initiation factor TFIID subunit 4 K03129 TAF4; transcription initiation factor TFIID subunit 4
E 100681291 TAF4B; transcription initiation factor TFIID subunit 4B isoform X1 K03129 TAF4; transcription initiation factor TFIID subunit 4
E 100081159 TAF5; transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E 100092867 TAF5L; TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L K03130 TAF5; transcription initiation factor TFIID subunit 5
E 100091361 TAF6; transcription initiation factor TFIID subunit 6 K03131 TAF6; transcription initiation factor TFIID subunit 6
E 114810219 TAF6L; TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L isoform X1 K03131 TAF6; transcription initiation factor TFIID subunit 6
E 100082773 TAF7L; transcription initiation factor TFIID subunit 7-like K03132 TAF7; transcription initiation factor TFIID subunit 7
E 100073806 transcription initiation factor TFIID subunit 7-like K03132 TAF7; transcription initiation factor TFIID subunit 7
E 100088300 TAF8; transcription initiation factor TFIID subunit 8 K14649 TAF8; transcription initiation factor TFIID subunit 8
E 100085912 TAF9B; transcription initiation factor TFIID subunit 9B K14535 TAF9; transcription initiation factor TFIID subunit 9
E 114805462 TAF10; transcription initiation factor TFIID subunit 10 K03134 TAF10; transcription initiation factor TFIID subunit 10
E 100089782 TAF11; transcription initiation factor TFIID subunit 11 K03135 TAF11; transcription initiation factor TFIID subunit 11
E 100091154 TAF12; transcription initiation factor TFIID subunit 12 K03126 TAF12; transcription initiation factor TFIID subunit 12
E 114811234 TAF13; transcription initiation factor TFIID subunit 13 K03127 TAF13; transcription initiation factor TFIID subunit 13
E 100089670 TAF15; TATA-binding protein-associated factor 2N isoform X2 K14651 TAF15; transcription initiation factor TFIID subunit 15
D TFIIE
E 100078968 GTF2E1; general transcription factor IIE subunit 1 K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
E 114817469 LOW QUALITY PROTEIN: general transcription factor IIE subunit 1-like K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
E 100091302 GTF2E2; transcription initiation factor IIE subunit beta isoform X1 K03137 TFIIE2; transcription initiation factor TFIIE subunit beta
D TFIIF
E 100074259 GTF2F1; general transcription factor IIF subunit 1 K03138 TFIIF1; transcription initiation factor TFIIF subunit alpha
E 100083959 GTF2F2; general transcription factor IIF subunit 2 K03139 TFIIF2; transcription initiation factor TFIIF subunit beta [EC:5.6.2.-]
D TFIIH
E 100078316 GTF2H1; general transcription factor IIH subunit 1 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E 100081699 GTF2H2; general transcription factor IIH subunit 2 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E 100076177 GTF2H3; general transcription factor IIH subunit 3 isoform X1 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E 103164668 GTF2H4; general transcription factor IIH subunit 4 isoform X1 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E 100681679 ERCC3; general transcription and DNA repair factor IIH helicase subunit XPB isoform X1 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 100091998 ERCC2; general transcription and DNA repair factor IIH helicase subunit XPD isoform X1 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 100093552 GTF2H5; general transcription factor IIH subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E 100074988 CDK7; cyclin-dependent kinase 7 isoform X1 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 100079002 MNAT1; CDK-activating kinase assembly factor MAT1 isoform X1 K10842 MNAT1; CDK-activating kinase assembly factor MAT1
E 100080058 CCNH; cyclin-H K06634 CCNH; cyclin H
C Mediator complex
D Head
E 100086815 MED6; mediator of RNA polymerase II transcription subunit 6 isoform X1 K15128 MED6; mediator of RNA polymerase II transcription subunit 6
E 100081911 MED8; mediator of RNA polymerase II transcription subunit 8 K15129 MED8; mediator of RNA polymerase II transcription subunit 8
E 114808041 MED11; mediator of RNA polymerase II transcription subunit 11 K15131 MED11; mediator of RNA polymerase II transcription subunit 11
E 100082483 MED17; mediator of RNA polymerase II transcription subunit 17 K15133 MED17; mediator of RNA polymerase II transcription subunit 17
E 100091483 MED18; mediator of RNA polymerase II transcription subunit 18 K15135 MED18; mediator of RNA polymerase II transcription subunit 18
E 100083349 MED19; mediator of RNA polymerase II transcription subunit 19 K15137 MED19; mediator of RNA polymerase II transcription subunit 19
E 100681499 MED20; mediator of RNA polymerase II transcription subunit 20 isoform X1 K13528 MED20; mediator of RNA polymerase II transcription subunit 20
E 100087702 MED22; mediator of RNA polymerase II transcription subunit 22 isoform X1 K15139 MED22; mediator of RNA polymerase II transcription subunit 22
E 100082298 MED28; mediator of RNA polymerase II transcription subunit 28 K15141 MED28; mediator of RNA polymerase II transcription subunit 28
E 114812054 MED29; mediator of RNA polymerase II transcription subunit 29 isoform X1 K15142 MED29; mediator of RNA polymerase II transcription subunit 29
E 100078066 MED30; mediator of RNA polymerase II transcription subunit 30 K15143 MED30; mediator of RNA polymerase II transcription subunit 30
D Middle
E 100092759 MED1; mediator of RNA polymerase II transcription subunit 1 K15144 MED1; mediator of RNA polymerase II transcription subunit 1
E 100083567 MED4; mediator of RNA polymerase II transcription subunit 4 K15146 MED4; mediator of RNA polymerase II transcription subunit 4
E 100089821 MED7; mediator of RNA polymerase II transcription subunit 7 K15148 MED7; mediator of RNA polymerase II transcription subunit 7
E 114805888 MED9; mediator of RNA polymerase II transcription subunit 9 K15149 MED9; mediator of RNA polymerase II transcription subunit 9
E 100080314 MED10; mediator of RNA polymerase II transcription subunit 10 isoform X1 K15151 MED10; mediator of RNA polymerase II transcription subunit 10
E 100073813 MED21; mediator of RNA polymerase II transcription subunit 21 K15152 MED21; mediator of RNA polymerase II transcription subunit 21
E 100093431 MED31; mediator of RNA polymerase II transcription subunit 31 K15153 MED31; mediator of RNA polymerase II transcription subunit 31
D Tail
E 100082286 MED14; mediator of RNA polymerase II transcription subunit 14 K15156 MED14; mediator of RNA polymerase II transcription subunit 14
E 100090582 mediator of RNA polymerase II transcription subunit 15 K15157 MED15; mediator of RNA polymerase II transcription subunit 15
E 103167399 mediator of RNA polymerase II transcription subunit 15-like isoform X1 K15157 MED15; mediator of RNA polymerase II transcription subunit 15
E 100079327 MED16; mediator of RNA polymerase II transcription subunit 16 isoform X1 K15159 MED16; mediator of RNA polymerase II transcription subunit 16
D CDK-module
E 100089343 CDK8; cyclin-dependent kinase 8 isoform X1 K02208 CDK8_11; cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23]
E 100080299 CDK19; cyclin-dependent kinase 19 isoform X1 K02208 CDK8_11; cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23]
E 100075291 CCNC; cyclin-C isoform X1 K15161 CCNC; cyclin-C
E 100682074 MED12L; mediator of RNA polymerase II transcription subunit 12-like protein K15162 MED12; mediator of RNA polymerase II transcription subunit 12
E 114812847 MED12; mediator of RNA polymerase II transcription subunit 12 K15162 MED12; mediator of RNA polymerase II transcription subunit 12
E 100078906 MED13; mediator of RNA polymerase II transcription subunit 13 K15164 MED13; mediator of RNA polymerase II transcription subunit 13
E 100074327 MED13L; mediator of RNA polymerase II transcription subunit 13-like K15164 MED13; mediator of RNA polymerase II transcription subunit 13
D Other mediators
E 100074297 MED23; mediator of RNA polymerase II transcription subunit 23 isoform X1 K15166 MED23; mediator of RNA polymerase II transcription subunit 23
E 100082257 MED24; mediator of RNA polymerase II transcription subunit 24 isoform X1 K15167 MED24; mediator of RNA polymerase II transcription subunit 24
E 100088935 MED25; mediator of RNA polymerase II transcription subunit 25 isoform X1 K15168 MED25; mediator of RNA polymerase II transcription subunit 25
E 100091503 MED26; mediator of RNA polymerase II transcription subunit 26 isoform X2 K15169 MED26; mediator of RNA polymerase II transcription subunit 26
E 114808722 mediator of RNA polymerase II transcription subunit 26 isoform X1 K15169 MED26; mediator of RNA polymerase II transcription subunit 26
E 114808720 mediator of RNA polymerase II transcription subunit 26 isoform X1 K15169 MED26; mediator of RNA polymerase II transcription subunit 26
E 100074934 MED27; mediator of RNA polymerase II transcription subunit 27 K15170 MED27; mediator of RNA polymerase II transcription subunit 27
C Coactivators
D SAGA/TFTC/STAGA complex
E 100077074 KAT2B; histone acetyltransferase KAT2B K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E 100084553 KAT2A; LOW QUALITY PROTEIN: histone acetyltransferase KAT2A K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E 100080669 transformation/transcription domain-associated protein isoform X1 K08874 TRRAP; transformation/transcription domain-associated protein
E 100087463 SUPT3H; transcription initiation protein SPT3 homolog isoform X1 K11313 SUPT3H; transcription initiation protein SPT3
E 103171420 TADA2A; transcriptional adapter 2-alpha K11314 TADA2A; transcriptional adapter 2-alpha
E 100091726 TADA2B; transcriptional adapter 2-beta K15127 TADA2B; transcriptional adapter 2-beta
E 100074842 TADA3; transcriptional adapter 3 isoform X2 K11315 TADA3; transcriptional adapter 3
E 100084503 TADA1; transcriptional adapter 1 K11317 TADA1; transcriptional adapter 1
E 100078775 TAF2; transcription initiation factor TFIID subunit 2 K03128 TAF2; transcription initiation factor TFIID subunit 2
E 100074124 TAF4; transcription initiation factor TFIID subunit 4 K03129 TAF4; transcription initiation factor TFIID subunit 4
E 100681291 TAF4B; transcription initiation factor TFIID subunit 4B isoform X1 K03129 TAF4; transcription initiation factor TFIID subunit 4
E 100081159 TAF5; transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E 100092867 TAF5L; TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L K03130 TAF5; transcription initiation factor TFIID subunit 5
E 100091361 TAF6; transcription initiation factor TFIID subunit 6 K03131 TAF6; transcription initiation factor TFIID subunit 6
E 114810219 TAF6L; TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L isoform X1 K03131 TAF6; transcription initiation factor TFIID subunit 6
E 100082773 TAF7L; transcription initiation factor TFIID subunit 7-like K03132 TAF7; transcription initiation factor TFIID subunit 7
E 100073806 transcription initiation factor TFIID subunit 7-like K03132 TAF7; transcription initiation factor TFIID subunit 7
E 100085912 TAF9B; transcription initiation factor TFIID subunit 9B K14535 TAF9; transcription initiation factor TFIID subunit 9
E 114805462 TAF10; transcription initiation factor TFIID subunit 10 K03134 TAF10; transcription initiation factor TFIID subunit 10
E 100091154 TAF12; transcription initiation factor TFIID subunit 12 K03126 TAF12; transcription initiation factor TFIID subunit 12
E 100091148 ATXN7L3; ataxin-7-like protein 3 isoform X1 K11363 SGF11; SAGA-associated factor 11
E 100092045 SGF29; SAGA-associated factor 29 K11364 SGF29; SAGA-associated factor 29
E 100077966 SUPT7L; STAGA complex 65 subunit gamma K11316 SUPT7L; STAGA complex 65 subunit gamma
E 100093478 ATXN7; ataxin-7 K11318 ATXN7; ataxin-7
E 100073510 ATXN7L2; ataxin-7-like protein 2 K11318 ATXN7; ataxin-7
E 100077585 ATXN7L1; ataxin-7-like protein 1 isoform X1 K11318 ATXN7; ataxin-7
E 100085332 ataxin-7-like K11318 ATXN7; ataxin-7
E 100082461 CHD1; chromodomain-helicase-DNA-binding protein 1 isoform X2 K11367 CHD1; chromodomain-helicase-DNA-binding protein 1 [EC:5.6.2.-]
E 100075677 ENY2; transcription and mRNA export factor ENY2 K11368 ENY2; enhancer of yellow 2 transcription factor
E 100080317 USP22; ubiquitin carboxyl-terminal hydrolase 22 isoform X1 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
E 100074472 SF3B3; splicing factor 3B subunit 3 K12830 SF3B3; splicing factor 3B subunit 3
D BAF/PBAF complex
E 100092816 SMARCA4; transcription activator BRG1 isoform X1 K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
E 100081844 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform X1 K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
E 100087859 SMARCC1; SWI/SNF complex subunit SMARCC1 K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
E 100085162 SMARCC2; SWI/SNF complex subunit SMARCC2 isoform X1 K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
E 100082608 SMARCD3; LOW QUALITY PROTEIN: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
E 114814784 SMARCD1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 isoform X1 K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
E 114815138 SMARCD2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
E 100086761 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X1 K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
E 100085078 ACTG1; actin, cytoplasmic 2 K05692 ACTB_G1; actin beta/gamma 1
E 100092493 actin, cytoplasmic type 5 K05692 ACTB_G1; actin beta/gamma 1
E 100078865 ACTB; actin, cytoplasmic 1 K05692 ACTB_G1; actin beta/gamma 1
E 100092810 ACTL6A; actin-like protein 6A K11340 ACTL6A; actin-like protein 6A
E 100089075 ACTL6B; actin-like protein 6B isoform X1 K11652 ACTL6B; actin-like protein 6B
E 100073902 ARID1B; LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 1B K11653 ARID1; AT-rich interactive domain-containing protein 1
E 103167718 ARID1A; LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 1A K11653 ARID1; AT-rich interactive domain-containing protein 1
E 100074437 ARID2; AT-rich interactive domain-containing protein 2 isoform X1 K11765 ARID2; AT-rich interactive domain-containing protein 2
E 103166093 PBRM1; protein polybromo-1 isoform X1 K11757 PBRM1; protein polybromo-1
D SWI/SNF complex
E 100081844 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform X1 K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
D RSC complex
D Others
E 100092955 SUB1; activated RNA polymerase II transcriptional coactivator p15 K25815 SUB1; activated RNA polymerase II transcriptional coactivator p15
E 100091761 CCAR1; cell division cycle and apoptosis regulator protein 1 isoform X1 K25827 CCAR1; cell division cycle and apoptosis regulator protein 1
E 114814738 CALCOCO1; calcium-binding and coiled-coil domain-containing protein 1 isoform X1 K25828 CALCOCO1; calcium-binding and coiled-coil domain-containing protein 1
C Other transcription-related factors
D Transcription elongation factors
E 100075902 TCEA2; transcription elongation factor A protein 2 isoform X2 K03145 TFIIS; transcription elongation factor S-II
E 100084032 TCEA1; transcription elongation factor A protein 1 K03145 TFIIS; transcription elongation factor S-II
E 100075282 TCEA3; transcription elongation factor A protein 3 isoform X1 K03145 TFIIS; transcription elongation factor S-II
E 103170974 SUPT4H1; LOW QUALITY PROTEIN: transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
E 100090453 SUPT5H; transcription elongation factor SPT5 isoform X1 K15172 SUPT5H; transcription elongation factor SPT5
E 100075897 SUPT6H; transcription elongation factor SPT6 isoform X1 K11292 SUPT6H; transcription elongation factor SPT6
D Transcription termination factor
E 100088112 TTF2; transcription termination factor 2 K15173 TTF2; transcription termination factor 2 [EC:5.6.2.-]
E 100083332 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
E 103165363 CPSF1; cleavage and polyadenylation specificity factor subunit 1 K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E 100073852 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 100081275 CPSF4; cleavage and polyadenylation specificity factor subunit 4 isoform X1 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 100093082 CPSF4L; putative cleavage and polyadenylation specificity factor subunit 4-like protein isoform X1 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 100074395 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit isoform X3 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 100078635 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 100092226 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform X1 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 103168651 SYMPK; symplekin K06100 SYMPK; symplekin
E 114812163 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 isoform X1 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
E 100074900 XRN2; 5'-3' exoribonuclease 2 isoform X1 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
E 100081395 DXO; decapping and exoribonuclease protein K14845 RAI1; RAT1-interacting protein
E 100081891 RPRD1A; regulation of nuclear pre-mRNA domain-containing protein 1A isoform X1 K15559 RTT103; regulator of Ty1 transposition protein 103
E 114806046 RPRD1B; regulation of nuclear pre-mRNA domain-containing protein 1B isoform X1 K15559 RTT103; regulator of Ty1 transposition protein 103
E 100082908 SFPQ; splicing factor, proline- and glutamine-rich K13219 SFPQ; splicing factor, proline- and glutamine-rich
E 100080363 SCAF8; SR-related and CTD-associated factor 8 isoform X2 K13191 RBM16; RNA-binding protein 16
E 100090979 SCAF4; SR-related and CTD-associated factor 4 isoform X1 K13167 SCAF4; SR-related and CTD-associated factor 4
E 103166025 SETX; probable helicase senataxin isoform X1 K10706 SETX; senataxin [EC:5.6.2.-]
E 114807447 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 K09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]
D PAF1 complex
E 114812049 PAF1; RNA polymerase II-associated factor 1 homolog K15174 PAF1; RNA polymerase II-associated factor 1
E 100086460 CDC73; parafibromin K15175 CDC73; parafibromin
E 100074677 CTR9; RNA polymerase-associated protein CTR9 homolog K15176 CTR9; RNA polymerase-associated protein CTR9
E 100081915 LEO1; RNA polymerase-associated protein LEO1 isoform X1 K15177 LEO1; RNA polymerase-associated protein LEO1
E 100073632 RTF1; RNA polymerase-associated protein RTF1 homolog isoform X1 K15178 RTF1; RNA polymerase-associated protein RTF1
D NELF complex
E 100092467 NELFA; LOW QUALITY PROTEIN: negative elongation factor A K15179 WHSC2; negative elongation factor A
E 100078500 NELFB; negative elongation factor B K15180 COBRA1; negative elongation factor B
E 100080417 NELFCD; negative elongation factor C/D K15181 TH1L; negative elongation factor C/D
E 100084282 NELFE; LOW QUALITY PROTEIN: negative elongation factor E K15182 RDBP; negative elongation factor E
D Super elongation complex (SEC)
E 100078071 ELL; RNA polymerase II elongation factor ELL isoform X1 K15183 ELL; RNA polymerase II elongation factor ELL
E 100081354 ELL2; RNA polymerase II elongation factor ELL2 K15183 ELL; RNA polymerase II elongation factor ELL
E 100088183 ELL3; RNA polymerase II elongation factor ELL3 isoform X1 K15183 ELL; RNA polymerase II elongation factor ELL
E 100085607 AFF1; AF4/FMR2 family member 1 isoform X3 K15184 AFF1; AF4/FMR2 family member 1
E 100079379 AFF4; AF4/FMR2 family member 4 isoform X1 K15185 AFF4; AF4/FMR2 family member 4
E 100083990 EAF1; ELL-associated factor 1 K15186 EAF; ELL-associated factor
E 100088092 ELL-associated factor 2-like K15186 EAF; ELL-associated factor
E 100082585 MLLT1; protein ENL isoform X1 K15187 MLLT1_3; YEATS domain-containing protein 1/3
E 100082672 MLLT3; protein AF-9 isoform X6 K15187 MLLT1_3; YEATS domain-containing protein 1/3
E 114808748 protein ENL-like isoform X1 K15187 MLLT1_3; YEATS domain-containing protein 1/3
E 100081231 CCNT1; cyclin-T1 K15188 CCNT; cyclin T
E 100089894 CCNT2; cyclin-T2 isoform X1 K15188 CCNT; cyclin T
E 100091817 CDK9; cyclin-dependent kinase 9 K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
D Little elongation complex (LEC)
E 100078071 ELL; RNA polymerase II elongation factor ELL isoform X1 K15183 ELL; RNA polymerase II elongation factor ELL
E 100081354 ELL2; RNA polymerase II elongation factor ELL2 K15183 ELL; RNA polymerase II elongation factor ELL
E 100088183 ELL3; RNA polymerase II elongation factor ELL3 isoform X1 K15183 ELL; RNA polymerase II elongation factor ELL
E 100080530 ICE1; little elongation complex subunit 1 isoform X2 K26143 ICE1; little elongation complex subunit 1
E 100079762 ICE2; little elongation complex subunit 2 isoform X1 K26144 ICE2; little elongation complex subunit 2
D Brd4/P-TEFb complex
E 100074736 BRD4; bromodomain-containing protein 4 isoform X1 K11722 BRD4; bromodomain-containing protein 4
E 100081231 CCNT1; cyclin-T1 K15188 CCNT; cyclin T
E 100089894 CCNT2; cyclin-T2 isoform X1 K15188 CCNT; cyclin T
E 100091817 CDK9; cyclin-dependent kinase 9 K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
D BUR kinase complex
D CTDK-I complex
D 7SK RNP complex
E 114814982 HEXIM1; protein HEXIM1 K15189 HEXIM1_2; protein HEXIM1/2
E 114815127 HEXIM2; LOW QUALITY PROTEIN: protein HEXIM2 K15189 HEXIM1_2; protein HEXIM1/2
E 100073867 MEPCE; 7SK snRNA methylphosphate capping enzyme K15190 MEPCE; 7SK snRNA methylphosphate capping enzyme [EC:2.1.1.-]
E 100075983 LARP7; la-related protein 7 isoform X1 K15191 LARP7; La-related protein 7
E 100081231 CCNT1; cyclin-T1 K15188 CCNT; cyclin T
E 100089894 CCNT2; cyclin-T2 isoform X1 K15188 CCNT; cyclin T
E 100091817 CDK9; cyclin-dependent kinase 9 K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
D DBIRD complex
E 100085599 CCAR2; cell cycle and apoptosis regulator protein 2 isoform X1 K25816 CCAR2; cell cycle and apoptosis regulator protein 2
E 100075888 ZNF326; DBIRD complex subunit ZNF326 isoform X3 K13204 ZNF326; zinc finger protein 326
D Others
E 100079439 GTF2I; LOW QUALITY PROTEIN: general transcription factor II-I K03121 TFII-I; transcription initiation factor TFII-I
E 100082193 GTF2IRD1; general transcription factor II-I repeat domain-containing protein 1 isoform X1 K27274 GTF2IRD1; general transcription factor II-I repeat domain-containing protein 1
E 100085830 BTAF1; TATA-binding protein-associated factor 172 isoform X1 K15192 BTAF1; TATA-binding protein-associated factor [EC:5.6.2.-]
E 100090682 DR1; protein Dr1 K21751 DR1; down-regulator of transcription 1
E 100092637 DRAP1; dr1-associated corepressor isoform X1 K21752 DRAP1; Dr1-associated corepressor
E 100088190 SPTY2D1; protein SPT2 homolog K15193 SPTY2D1; protein SPT2
E 100081702 AFF2; AF4/FMR2 family member 2 isoform X1 K15194 AFF2; AF4/FMR2 family member 2
E 100075957 AFF3; AF4/FMR2 family member 3 isoform X2 K15195 AFF3; AF4/FMR2 family member 3
E 100078008 CTDP1; RNA polymerase II subunit A C-terminal domain phosphatase isoform X2 K15732 CTDP1; RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16]
E 100078746 CTDSP2; LOW QUALITY PROTEIN: carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 K15731 CTDSP; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16]
E 100092789 CTDSPL; CTD small phosphatase-like protein isoform X2 K15731 CTDSP; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16]
E 114812902 CTDSP1; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 K15731 CTDSP; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16]
E 100079588 IWS1; protein IWS1 homolog isoform X1 K17498 SPN1; transcription factor SPN1
E 100082895 CSRNP3; cysteine/serine-rich nuclear protein 3 K17494 CSRNP; cysteine/serine-rich nuclear protein
E 100088746 CSRNP1; cysteine/serine-rich nuclear protein 1 K17494 CSRNP; cysteine/serine-rich nuclear protein
E 114814566 CSRNP2; cysteine/serine-rich nuclear protein 2 K17494 CSRNP; cysteine/serine-rich nuclear protein
E 103167275 RPAP1; RNA polymerase II-associated protein 1 K20826 RPAP1; RNA polymerase II-associated protein 1
E 100092237 RPAP2; putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 isoform X1 K20827 RPAP2; RNA polymerase II-associated protein 2 [EC:3.1.3.16]
E 100075044 RPAP3; RNA polymerase II-associated protein 3 isoform X1 K23002 RPAP3; RNA polymerase II-associated protein 3
E 100084966 CCNK; cyclin-K K23326 CCNK; cyclin K
E 100089830 GPN2; GPN-loop GTPase 2 K24104 GPN; GPN-loop GTPase
E 100074099 GPN3; GPN-loop GTPase 3 K24104 GPN; GPN-loop GTPase
E 103169415 GPN1; GPN-loop GTPase 1 K24104 GPN; GPN-loop GTPase
B RNA polymerase III system
C RNA polymerase III
D Core subunits
E 100084195 POLR3A; DNA-directed RNA polymerase III subunit RPC1 K03018 RPC1; DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6]
E 100077080 POLR3B; DNA-directed RNA polymerase III subunit RPC2 K03021 RPC2; DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6]
E 100084895 POLR1C; DNA-directed RNA polymerases I and III subunit RPAC1 K03027 RPAC1; DNA-directed RNA polymerases I and III subunit RPAC1
E 100084369 DNA-directed RNA polymerases I and III subunit RPAC2-like isoform X1 K03020 RPAC2; DNA-directed RNA polymerases I and III subunit RPAC2
D Pol III specific subunits
E 100089929 POLR3C; LOW QUALITY PROTEIN: DNA-directed RNA polymerase III subunit RPC3 K03023 RPC3; DNA-directed RNA polymerase III subunit RPC3
E 100087407 POLR3D; DNA-directed RNA polymerase III subunit RPC4 K03026 RPC4; DNA-directed RNA polymerase III subunit RPC4
E 100076999 POLR3E; DNA-directed RNA polymerase III subunit RPC5 isoform X1 K14721 RPC5; DNA-directed RNA polymerase III subunit RPC5
E 100085159 POLR3F; DNA-directed RNA polymerase III subunit RPC6 isoform X1 K03025 RPC6; DNA-directed RNA polymerase III subunit RPC6
E 100077015 POLR3G; DNA-directed RNA polymerase III subunit RPC7 isoform X1 K03024 RPC7; DNA-directed RNA polymerase III subunit RPC7
E 103168393 POLR3GL; DNA-directed RNA polymerase III subunit RPC7-like K03024 RPC7; DNA-directed RNA polymerase III subunit RPC7
E 100088104 POLR3H; DNA-directed RNA polymerase III subunit RPC8 K03022 RPC8; DNA-directed RNA polymerase III subunit RPC8
E 100091658 POLR3K; DNA-directed RNA polymerase III subunit RPC10 K03019 RPC11; DNA-directed RNA polymerase III subunit RPC11
D Pol I, II, III common subunits
E 100090631 POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
E 100089660 POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
E 100074090 POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E 114810046 POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
C Basal transcription factors
D TFIIIA
E 100090303 GTF3A; transcription factor IIIA K09191 GTF3A; general transcription factor IIIA
D TFIIIB
E 100082878 TBPL2; TATA box-binding protein-like 2 isoform X1 K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
E 100075429 TBPL1; TATA box-binding protein-like 1 K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
E 100091633 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
E 100091951 BRF1; transcription factor IIIB 90 kDa subunit isoform X1 K15196 BRF1; transcription factor IIIB 90 kDa subunit
E 100091065 BRF2; transcription factor IIIB 50 kDa subunit K15197 BRF2; transcription factor IIIB 50 kDa subunit
E 100081811 BDP1; transcription factor TFIIIB component B'' homolog isoform X1 K15198 BDP1; transcription factor TFIIIB component B''
D TFIIIC
E 100079485 GTF3C1; general transcription factor 3C polypeptide 1 K15199 GTF3C1; general transcription factor 3C polypeptide 1
E 100085966 GTF3C2; general transcription factor 3C polypeptide 2 isoform X1 K15200 GTF3C2; general transcription factor 3C polypeptide 2
E 103168270 GTF3C3; general transcription factor 3C polypeptide 3 isoform X1 K15201 GTP3C3; general transcription factor 3C polypeptide 3 (transcription factor C subunit 4)
E 100080497 GTF3C4; general transcription factor 3C polypeptide 4 K11310 GTF3C4; general transcription factor 3C polypeptide 4 [EC:2.3.1.48]
E 100080764 GTF3C5; general transcription factor 3C polypeptide 5 K15202 GTF3C5; general transcription factor 3C polypeptide 5 (transcription factor C subunit 1)
E 100073395 GTF3C6; general transcription factor 3C polypeptide 6 K15203 GTF3C6; general transcription factor 3C polypeptide 6
D TFIIIC, fungi type
E 100080764 GTF3C5; general transcription factor 3C polypeptide 5 K15202 GTF3C5; general transcription factor 3C polypeptide 5 (transcription factor C subunit 1)
E 103168270 GTF3C3; general transcription factor 3C polypeptide 3 isoform X1 K15201 GTP3C3; general transcription factor 3C polypeptide 3 (transcription factor C subunit 4)
C Other transcription-related factors
D snRNA-activating protein complex (SNAPc)
E 100080099 SNAPC1; snRNA-activating protein complex subunit 1 isoform X2 K15208 SNAPC1; snRNA-activating protein complex subunit 1
E 103167313 SNAPC2; snRNA-activating protein complex subunit 2 K15209 SNAPC2; snRNA-activating protein complex subunit 2
E 100076501 SNAPC3; snRNA-activating protein complex subunit 3 K15210 SNAPC3; snRNA-activating protein complex subunit 3
E 100082589 SNAPC4; snRNA-activating protein complex subunit 4 isoform X1 K09453 SNAPC4; snRNA-activating protein complex subunit 4
E 100080226 SNAPC5; snRNA-activating protein complex subunit 5 K15211 SNAPC5; snRNA-activating protein complex subunit 5
D Octamer transcription factors
E 100082552 POU2F1; LOW QUALITY PROTEIN: POU domain, class 2, transcription factor 1 K09364 POU2F; POU domain transcription factor, class 2
E 100083699 POU2F3; POU domain, class 2, transcription factor 3 K09364 POU2F; POU domain transcription factor, class 2
E 100081261 POU2F2; POU domain, class 2, transcription factor 2 isoform X1 K09364 POU2F; POU domain transcription factor, class 2
E 100091458 POU5F1; POU domain, class 5, transcription factor 1 K09367 POU5F; POU domain transcription factor, class 5
E 114807791 POU domain, class 5, transcription factor 3-like K09367 POU5F; POU domain transcription factor, class 5
D Others
E 100078576 ZNF143; zinc finger protein 143 isoform X1 K20828 ZNF143_76; zinc finger protein 143/76
E 103166435 ZNF76; zinc finger protein 76 K20828 ZNF143_76; zinc finger protein 143/76
E 107546953 MAF1; repressor of RNA polymerase III transcription MAF1 homolog K25817 MAF1; repressor of RNA polymerase III transcription MAF1
B RNA polymerase I system
C RNA polymerase I
D Core subunits
E 100081206 POLR1A; DNA-directed RNA polymerase I subunit RPA1 K02999 RPA1; DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6]
E 100085323 POLR1B; DNA-directed RNA polymerase I subunit RPA2 K03002 RPA2; DNA-directed RNA polymerase I subunit RPA2 [EC:2.7.7.6]
E 100084895 POLR1C; DNA-directed RNA polymerases I and III subunit RPAC1 K03027 RPAC1; DNA-directed RNA polymerases I and III subunit RPAC1
E 100084369 DNA-directed RNA polymerases I and III subunit RPAC2-like isoform X1 K03020 RPAC2; DNA-directed RNA polymerases I and III subunit RPAC2
D Pol I specific subunits
E 100087062 POLR1E; DNA-directed RNA polymerase I subunit RPA49 isoform X2 K03005 RPA49; DNA-directed RNA polymerase I subunit RPA49
E 100083611 POLR1F; DNA-directed RNA polymerase I subunit RPA43 K03004 RPA43; DNA-directed RNA polymerase I subunit RPA43
E 103165597 POLR1G; DNA-directed RNA polymerase I subunit RPA34 K25436 POLR1G; DNA-directed RNA polymerase I subunit RPA34
E 100085141 POLR1H; DNA-directed RNA polymerase I subunit RPA12 K03000 RPA12; DNA-directed RNA polymerase I subunit RPA12
D Pol I, II, III common subunits
E 100090631 POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
E 100089660 POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
E 100074090 POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E 114810046 POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
C Basal transcription factors
D SL1/TIF-1B
E 100082878 TBPL2; TATA box-binding protein-like 2 isoform X1 K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
E 100075429 TBPL1; TATA box-binding protein-like 1 K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
E 100091633 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
E 100081271 TAF1A; TATA box-binding protein-associated factor RNA polymerase I subunit A K15212 TAF1A; TATA box-binding protein-associated factor RNA polymerase I subunit A
E 100076574 TAF1B; TATA box-binding protein-associated factor RNA polymerase I subunit B isoform X1 K15213 TAF1B; TATA box-binding protein-associated factor RNA polymerase I subunit B
E 100681555 TAF1C; TATA box-binding protein-associated factor RNA polymerase I subunit C K15214 TAF1C; TATA box-binding protein-associated factor RNA polymerase I subunit C
E 100082369 TAF1D; TATA box-binding protein-associated factor RNA polymerase I subunit D isoform X1 K15215 TAF1D; TATA box-binding protein-associated factor RNA polymerase I subunit D
C Other transcription-related factors
D UBF
E 114815165 UBTF; LOW QUALITY PROTEIN: nucleolar transcription factor 1 K09273 UBTF; upstream-binding transcription factor
D Transcription initiation factors
E 100089040 RRN3; RNA polymerase I-specific transcription initiation factor RRN3 K15216 RRN3; RNA polymerase I-specific transcription initiation factor RRN3
D Transcription elongation factors
E 103170974 SUPT4H1; LOW QUALITY PROTEIN: transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
E 100090453 SUPT5H; transcription elongation factor SPT5 isoform X1 K15172 SUPT5H; transcription elongation factor SPT5
D NoRC (nucleolar remodeling complex)
E 100082610 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
E 100078382 BAZ2A; bromodomain adjacent to zinc finger domain protein 2A K15224 BAZ2A; bromodomain adjacent to zinc finger domain protein 2A
D CTDK-I complex
D Transcription termination factors
E 100681314 TTF1; transcription termination factor 1 isoform X1 K15225 TTF1; transcription termination factor 1
E 100093475 CAVIN1; caveolae-associated protein 1 K19387 PTRF; polymerase I and transcript release factor
D Others
E 100080181 NOLC1; nucleolar and coiled-body phosphoprotein 1 isoform X1 K25818 NOLC1; nucleolar and coiled-body phosphoprotein 1
#
AProkaryotic type
B Bacterial type
C RNA polymerase
D Core subunits
D Sigma factors
C Other transcription-related factors
D RNA polymerase-associated proteins
D Transcription elongation factors
D Transcription termination factor
B Archaeal type
C RNA polymerase
D Core subunits
C Basal transcription factors
D TFB
E 100076897 GTF2B; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D TFE
E 100078968 GTF2E1; general transcription factor IIE subunit 1 K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
E 114817469 LOW QUALITY PROTEIN: general transcription factor IIE subunit 1-like K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D TFS
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 9, 2024