+D AMR gene KO
#
Antimicrobial Resistance Genes - Pseudomonas aeruginosa LESB58
%
!
AGene variants
B beta-Lactamase genes
C Class A [MT]
C Class D [MT]
D PLES_59101 probable beta-lactamase K18973 blaOXA-50; beta-lactamase class D OXA-50 [EC:3.5.2.6]
C Class C [MT]
D PLES_08611 ampC; beta-lactamase precursor K20320 blaPDC; beta-lactamase class C PDC [EC:3.5.2.6]
C Class B [MT]
B Aminoglycoside resistance genes
C N-Acetyltransferases
C Other acetyltransferases
C O-Nucleotidyltransferases
C O-Phosphotransferases
D PLES_08521 aph; aminoglycoside 3'-phosphotransferase type IIb K19300 aph3-II; aminoglycoside 3'-phosphotransferase II [EC:2.7.1.95]
D PLES_34661 str; streptomycin 3''-phosphotransferase K04343 strB; streptomycin 6-kinase [EC:2.7.1.72]
C 16S rRNA methyltransferases
B Tetracycline resistance genes
C Transporters
D PLES_41881 probable major facilitator superfamily (MFS) transporter K08151 tetA; MFS transporter, DHA1 family, tetracycline resistance protein
C Others
B Macrolide resistance genes
C 23S rRNA methyltransferases
C Transporters
C Others
D PLES_04641 putative streptogramin lyase K18235 vgb; virginiamycin B lyase [EC:4.2.99.-]
D PLES_03251 conserved hypothetical protein K18234 vat; virginiamycin A acetyltransferase [EC:2.3.1.-]
B Phenicol resistance genes
C Transporters
D PLES_17281 probable major facilitator superfamily (MFS) transporter K18553 cmlR; MFS transporter, DHA1 family, chloramphenicol resistance protein
C Acetyltransferases
D PLES_46241 cat; chloramphenicol acetyltransferase K00638 catB; chloramphenicol O-acetyltransferase type B [EC:2.3.1.28]
D PLES_11211 probable transferase K00638 catB; chloramphenicol O-acetyltransferase type B [EC:2.3.1.28]
C Phosphotransferase
C 23S rRNA methyltransferase
B Sulfonamide resistance genes
C Dihydropteroate synthase
B Trimethoprim resistance genes
C Dihydrofolate reductases
B Quinolone resistance genes
C Transporter
D PLES_40301 probable major facilitator superfamily (MFS) transporter K08167 smvA; MFS transporter, DHA2 family, multidrug resistance protein
C Other
B Rifamycin resistance genes
C ADP-ribosyl transferases
C Oxygenases
B Fosfomycin resistance genes
C Transferases
D PLES_41901 probable fosfomycin resistance protein K21253 fosA; glutathione S-transferase fosA [EC:2.5.1.18]
C Others
#
AGene sets
B beta-Lactam resistance modules
C Methicillin resistance [MD:M00625]
C beta-Lactam resistance, Bla system [MD:M00627]
C Imipenem resistance, repression of porin OprD [MD:M00745]
D PLES_35301 probable two-component sensor K18072 parS; two-component system, OmpR family, sensor kinase ParS [EC:2.7.13.3]
D PLES_35291 probable two-component response regulator K18073 parR; two-component system, OmpR family, response regulator ParR
D PLES_52721 probable two-component sensor K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
D PLES_27711 probable two-component sensor K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
D PLES_22621 copS; two-component sensor, CopS K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
D PLES_39761 probable two-component sensor K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
D PLES_52711 irlR; two-component response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
D PLES_27721 probable two-component response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
D PLES_39771 probable two-component response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
D PLES_22631 copR; two-component response regulator, CopR K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
D PLES_43561 oprD; Basic amino acid, basic peptide and imipenem outer membrane porin OprD precursor K18093 oprD; imipenem/basic amino acid-specific outer membrane pore [EC:3.4.21.-]
D PLES_24041 opdB; proline porin OpdB K18093 oprD; imipenem/basic amino acid-specific outer membrane pore [EC:3.4.21.-]
D PLES_01901 probable porin K18093 oprD; imipenem/basic amino acid-specific outer membrane pore [EC:3.4.21.-]
B Vancomycin resistance modules
C Vancomycin resistance, D-Ala-D-Lac type [MD:M00651]
D PLES_45941 hypothetical protein K18346 vanW; vancomycin resistance protein VanW
C Vancomycin resistance, D-Ala-D-Ser type [MD:M00652]
D B Tetracycline resistance
C Tetracycline resistance, efflux pump Tet38 [MD:M00704]
B CAMP resistance modules
C Cationic antimicrobial peptide (CAMP) resistance, dltABCD operon [MD:M00725]
D PLES_25801 pltL; PltL K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
C Cationic antimicrobial peptide (CAMP) resistance, lysyl-phosphatidylglycerol (L-PG) synthase MprF [MD:M00726]
D PLES_43961 hypothetical protein K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
C Cationic antimicrobial peptide (CAMP) resistance, VraFG transporter [MD:M00730]
C Cationic antimicrobial peptide (CAMP) resistance, protease PgtE [MD:M00744]
D PLES_41411 phoQ; two-component sensor PhoQ K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
D PLES_41421 phoP; two-component response regulator PhoP K07660 phoP; two-component system, OmpR family, response regulator PhoP
B Multipdrug resistance modules
C Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
D PLES_04221 mexR; multidrug resistance operon repressor MexR K18131 mexR; MarR family transcriptional regulator, repressor of the mexAB-oprM multidrug resistance operon
D PLES_04231 mexA; Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexA precursor K03585 acrA; membrane fusion protein, multidrug efflux system
D PLES_47531 probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor K03585 acrA; membrane fusion protein, multidrug efflux system
D PLES_04241 mexB; Resistance-Nodulation-Cell Division (RND) multidrug efflux transporter MexB K18138 acrB; multidrug efflux pump
D PLES_47541 probable Resistance-Nodulation-Cell Division (RND) efflux transporter K18138 acrB; multidrug efflux pump
D PLES_26291 RND efflux system, outer membrane lipoprotein, NodT family K18139 oprM; outer membrane protein, multidrug efflux system
D PLES_04251 oprM; Major intrinsic multiple antibiotic resistance efflux outer membrane protein OprM precursor K18139 oprM; outer membrane protein, multidrug efflux system
C Multidrug resistance, efflux pump MexCD-OprJ [MD:M00639]
D PLES_49851 nfxB; transcriptional regulator NfxB K18294 nfxB; TetR/AcrR family transcriptional regulator, mexCD-oprJ operon repressor
D PLES_49841 mexC; Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexC precursor K18295 mexC; membrane fusion protein, multidrug efflux system
D PLES_49831 mexD; Resistance-Nodulation-Cell Division (RND) multidrug efflux transporter MexD K18296 mexD; multidrug efflux pump
C Multidrug resistance, efflux pump MexEF-OprN [MD:M00641]
D PLES_28031 mexE; Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexE precursor K18298 mexE; membrane fusion protein, multidrug efflux system
D PLES_28001 oprN; Multidrug efflux outer membrane protein OprN precursor K18300 oprN; outer membrane protein, multidrug efflux system
C Multidrug resistance, efflux pump MexJK-OprM [MD:M00642]
D PLES_13061 probable transcriptional regulator K18301 mexL; TetR/AcrR family transcriptional regulator, mexJK operon transcriptional repressor
D PLES_13071 probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor K18302 mexJ; membrane fusion protein, multidrug efflux system
D PLES_13081 probable Resistance-Nodulation-Cell Division (RND) efflux transporter K18303 mexK; multidrug efflux pump
D PLES_26291 RND efflux system, outer membrane lipoprotein, NodT family K18139 oprM; outer membrane protein, multidrug efflux system
D PLES_04251 oprM; Major intrinsic multiple antibiotic resistance efflux outer membrane protein OprM precursor K18139 oprM; outer membrane protein, multidrug efflux system
C Multidrug resistance, efflux pump MexXY-OprM [MD:M00643]
D PLES_33041 Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein precursor K18094 mexX; membrane fusion protein, multidrug efflux system
D PLES_33051 Resistance-Nodulation-Cell Division (RND) multidrug efflux transporter K18095 mexY; multidrug efflux pump
D PLES_26291 RND efflux system, outer membrane lipoprotein, NodT family K18139 oprM; outer membrane protein, multidrug efflux system
D PLES_04251 oprM; Major intrinsic multiple antibiotic resistance efflux outer membrane protein OprM precursor K18139 oprM; outer membrane protein, multidrug efflux system
C Multidrug resistance, efflux pump MexPQ-OpmE [MD:M00769]
D PLES_39841 lasR; transcriptional regulator LasR K18304 lasR; LuxR family transcriptional regulator, quorum-sensing system regulator LasR
D PLES_51631 probable transcriptional regulator K19591 cueR; MerR family transcriptional regulator, copper efflux regulator
D PLES_15101 probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor K19595 gesA; membrane fusion protein, gold/copper resistance efflux system
D PLES_26271 efflux transporter, RND family, MFP subunit K19595 gesA; membrane fusion protein, gold/copper resistance efflux system
D PLES_15111 probable Resistance-Nodulation-Cell Division (RND) efflux transporter K19594 gesB; gold/copper resistance efflux pump
D PLES_26281 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family K19594 gesB; gold/copper resistance efflux pump
D PLES_15121 probable outer membrane protein precursor K19593 opmE; outer membrane protein, multidrug efflux system
C Multidrug resistance, efflux pump AdeABC [PATH:map01501] [MD:M00649]
C Multidrug resistance, efflux pump AcrEF-TolC [MD:M00696]
D PLES_53621 probable outer membrane protein precursor K12340 tolC; outer membrane protein
D PLES_07831 probable outer membrane protein precursor K12340 tolC; outer membrane protein
D PLES_49761 probable outer membrane protein precursor K12340 tolC; outer membrane protein
C Multidrug resistance, efflux pump MdtEF-TolC [MD:M00697]
D PLES_10271 rocA1; two-component response regulator RocA1 K07690 evgA; two-component system, NarL family, response regulator EvgA
D PLES_20151 probable two-component response regulator K07690 evgA; two-component system, NarL family, response regulator EvgA
D PLES_00331 probable two-component response regulator K07690 evgA; two-component system, NarL family, response regulator EvgA
D PLES_53621 probable outer membrane protein precursor K12340 tolC; outer membrane protein
D PLES_07831 probable outer membrane protein precursor K12340 tolC; outer membrane protein
D PLES_49761 probable outer membrane protein precursor K12340 tolC; outer membrane protein
C Multidrug resistance, efflux pump BpeEF-OprC [MD:M00698]
D PLES_32651 probable transcriptional regulator K18900 bpeT; LysR family transcriptional regulator, regulator for bpeEF and oprC
C Multidrug resistance, efflux pump AbcA [MD:M00700]
C Multidrug resistance, efflux pump NorB [MD:M00702]
C Multidrug resistance, efflux pump QacA [MD:M00714]
D PLES_40301 probable major facilitator superfamily (MFS) transporter K08167 smvA; MFS transporter, DHA2 family, multidrug resistance protein
C Multidrug resistance, efflux pump MepA [MD:M00705]
C Multidrug resistance, repression of porin OmpF [MD:M00746]
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 28, 2017