+C Lipid biosynthesis protein KO #

  Lipid Biosynthesis Proteins - Pan paniscus (bonobo)

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AFatty acid synthase B Animal type C 100985873 FASN; fatty acid synthase K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85] B Yeast type B Bacteria type B Component type C 100990465 MCAT; malonyl-CoA-acyl carrier protein transacylase, mitochondrial isoform X1 K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] C 100991335 OXSM; 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] C 100971612 HSD17B12; very-long-chain 3-oxoacyl-CoA reductase K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330] C 100986064 HACD3; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 isoform X2 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134] C 100995506 HACD4; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 isoform X2 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134] C 100970660 HACD1; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 isoform X1 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134] C 100979084 HACD2; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134] C 100978479 PECR; peroxisomal trans-2-enoyl-CoA reductase K07753 PECR; peroxisomal trans-2-enoyl-CoA reductase [EC:1.3.1.38] C 100971383 TECR; very-long-chain enoyl-CoA reductase isoform X3 K10258 TER; very-long-chain enoyl-CoA reductase [EC:1.3.1.93] C 100969629 OLAH; LOW QUALITY PROTEIN: S-acyl fatty acid synthase thioesterase, medium chain K01071 MCH; medium-chain acyl-[acyl-carrier-protein] hydrolase [EC:3.1.2.21] C 100969155 PPT1; palmitoyl-protein thioesterase 1 K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22] C 100989791 PPT2; lysosomal thioesterase PPT2 isoform X1 K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22] C 100973111 ACOT4; peroxisomal succinyl-coenzyme A thioesterase K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2] C 100971608 ACOT2; acyl-coenzyme A thioesterase 2, mitochondrial isoform X1 K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2] C 100971945 ACOT6; putative acyl-coenzyme A thioesterase 6 K11993 ACOT6; acyl-CoA thioesterase 6 [EC:3.1.2.-] C 100977829 ACOT7; cytosolic acyl coenzyme A thioester hydrolase isoform X1 K17360 ACOT7; acyl-coenzyme A thioesterase 7 [EC:3.1.2.2] C 100978366 LOW QUALITY PROTEIN: putative cytosolic acyl coenzyme A thioester hydrolase-like K17360 ACOT7; acyl-coenzyme A thioesterase 7 [EC:3.1.2.2] C 100991851 ACOT9; acyl-coenzyme A thioesterase 9, mitochondrial isoform X2 K17361 ACOT9; acyl-coenzyme A thioesterase 9 [EC:3.1.2.-] C 100975192 ACOT11; acyl-coenzyme A thioesterase 11 isoform X3 K12417 ACOT11; acyl-CoA thioesteraes 11 [EC:3.1.2.-] C 100975134 ACOT13; acyl-coenzyme A thioesterase 13 isoform X2 K17362 ACOT13; acyl-coenzyme A thioesterase 13 [EC:3.1.2.-] # ADesaturase B First C 100968188 SCD; acyl-CoA desaturase K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1] C 100971802 SCD5; stearoyl-CoA desaturase 5 K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1] B Omega C 100980260 FADS3; fatty acid desaturase 3 isoform X4 K10225 FADS3; fatty acid desaturase 3 (Delta-13 desaturase) [EC:1.14.19.-] B Front-end C 100981162 FADS1; acyl-CoA (8-3)-desaturase isoform X1 K10224 FADS1; acyl-CoA (8-3)-desaturase (Delta-5 desaturase) [EC:1.14.19.44] C 100980611 FADS2; acyl-CoA 6-desaturase isoform X2 K10226 FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3] B Sphingolipid C 100979702 DEGS2; sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 isoform X1 K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5] C 100990486 DEGS1; sphingolipid delta(4)-desaturase DES1 isoform X1 K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5] B Other C 100989100 FADS6; fatty acid desaturase 6 K12419 FADS6; fatty acid desaturase 6 [EC:1.14.19.-] # AElongase B LCFA B PUFA C 100986082 ELOVL1; elongation of very long chain fatty acids protein 1 isoform X1 K10247 ELOVL1; elongation of very long chain fatty acids protein 1 [EC:2.3.1.199] C 100979903 ELOVL2; elongation of very long chain fatty acids protein 2 isoform X1 K10205 ELOVL2; elongation of very long chain fatty acids protein 2 [EC:2.3.1.199] C 100968249 ELOVL4; elongation of very long chain fatty acids protein 4 K10249 ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199] C 100995722 ELOVL5; elongation of very long chain fatty acids protein 5 isoform X2 K10244 ELOVL5; elongation of very long chain fatty acids protein 5 [EC:2.3.1.199] C 100976431 ELOVL6; elongation of very long chain fatty acids protein 6 K10203 ELOVL6; elongation of very long chain fatty acids protein 6 [EC:2.3.1.199] C 100973834 ELOVL7; elongation of very long chain fatty acids protein 7 isoform X1 K10250 ELOVL7; elongation of very long chain fatty acids protein 7 [EC:2.3.1.199] B Unclassified C 100984036 ELOVL3; elongation of very long chain fatty acids protein 3 isoform X1 K10248 ELOVL3; elongation of very long chain fatty acids protein 3 [EC:2.3.1.199] # APolyketide synthase B Modular PKS B Component type # AAcyl-CoA synthetase B Short/medium chain acyl-CoA synthetase C 100975174 ACSS1; acetyl-coenzyme A synthetase 2-like, mitochondrial isoform X1 K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] C 100979472 ACSS2; acetyl-coenzyme A synthetase, cytoplasmic isoform X2 K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] C 100978446 ACSS3; acyl-CoA synthetase short-chain family member 3, mitochondrial isoform X1 K01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17] C 100983892 AACS; acetoacetyl-CoA synthetase isoform X1 K01907 AACS; acetoacetyl-CoA synthetase [EC:6.2.1.16] C 100972336 acyl-coenzyme A synthetase ACSM1, mitochondrial K23756 ACSM1; medium-chain acyl-CoA ligase / lipoate-activating enzyme [EC:6.2.1.2] C 100992481 ACSM4; acyl-coenzyme A synthetase ACSM4, mitochondrial K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2] C 100995253 ACSM3; acyl-coenzyme A synthetase ACSM3, mitochondrial isoform X1 K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2] C 100968187 ACSM6; acyl-coenzyme A synthetase ACSM6, mitochondrial K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2] C 100994985 acyl-coenzyme A synthetase ACSM2B, mitochondrial K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2] C 100994660 acyl-coenzyme A synthetase ACSM2A, mitochondrial K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2] C 100973540 acyl-coenzyme A synthetase ACSM5, mitochondrial-like K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2] C 100984659 acyl-coenzyme A synthetase ACSM5, mitochondrial isoform X1 K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2] C 100986228 ACSF2; medium-chain acyl-CoA ligase ACSF2, mitochondrial K23617 ACSF2; medium-chain acyl-CoA ligase, mitochondrial [EC:6.2.1.2] B Long/very long chain acyl-CoA synthetase C 100985252 ACSL4; long-chain-fatty-acid--CoA ligase 4 isoform X4 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 100976380 ACSL1; long-chain-fatty-acid--CoA ligase 1 isoform X1 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 100982029 ACSL5; long-chain-fatty-acid--CoA ligase 5 isoform X1 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 100967641 ACSL6; long-chain-fatty-acid--CoA ligase 6 isoform X1 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 100977696 ACSL3; long-chain-fatty-acid--CoA ligase 3 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 100987318 ACSBG1; long-chain-fatty-acid--CoA ligase ACSBG1 isoform X1 K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3] C 100987114 ACSBG2; long-chain-fatty-acid--CoA ligase ACSBG2 isoform X1 K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3] C 100981427 SLC27A1; long-chain fatty acid transport protein 1 isoform X1 K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-] C 100972191 SLC27A4; long-chain fatty acid transport protein 4 K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-] C 100968109 SLC27A2; very long-chain acyl-CoA synthetase isoform X1 K08746 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3] C 100983082 SLC27A3; solute carrier family 27 member 3 K08772 SLC27A3; solute carrier family 27 (fatty acid transporter), member 3 [EC:6.2.1.-] B Unknown C 100991203 AASDH; beta-alanine-activating enzyme isoform X2 K00142 AASDH; acyl-CoA synthetase [EC:6.2.1.-] # APhospholipid acyltransferase B GPAT C 100981357 GPAM; glycerol-3-phosphate acyltransferase 1, mitochondrial K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15] C 100985241 glycerol-3-phosphate acyltransferase 2, mitochondrial K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15] C 100977471 LOW QUALITY PROTEIN: glycerol-3-phosphate acyltransferase 2, mitochondrial-like K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15] C 100995208 GPAT4; glycerol-3-phosphate acyltransferase 4 isoform X1 K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15] C 100991224 LOW QUALITY PROTEIN: glycerol-3-phosphate acyltransferase 4-like K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15] C 100981535 GPAT3; glycerol-3-phosphate acyltransferase 3 isoform X1 K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15] B LPAAT/LPLAT C 100977572 AGPAT2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51] C 100991029 AGPAT1; 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51] C 100982356 ABHD5; 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform X1 K13699 ABHD5; abhydrolase domain-containing protein 5 [EC:2.3.1.51] C 100982937 LCLAT1; lysocardiolipin acyltransferase 1 isoform X2 K13513 LCLAT1; lysocardiolipin and lysophospholipid acyltransferase [EC:2.3.1.- 2.3.1.51] C 100979973 TAZ; tafazzin isoform X8 K13511 TAZ; monolysocardiolipin acyltransferase [EC:2.3.1.-] C 100968517 MBOAT1; lysophospholipid acyltransferase 1 K13517 MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-] C 100986055 MBOAT2; lysophospholipid acyltransferase 2 isoform X3 K13517 MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-] C 100980774 AGPAT4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta K13523 AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-] C 100968639 AGPAT3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform X1 K13523 AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-] C 100970278 LPCAT2; lysophosphatidylcholine acyltransferase 2 isoform X1 K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67] C 100991866 LPCAT1; lysophosphatidylcholine acyltransferase 1 K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67] C 100994535 LPCAT4; lysophospholipid acyltransferase LPCAT4 K13512 LPCAT4; lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-] C 100976771 LPGAT1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 isoform X2 K13514 LPGAT1; lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-] C 100991640 LPCAT3; lysophospholipid acyltransferase 5 isoform X1 K13515 LPCAT3; lysophospholipid acyltransferase 5 [EC:2.3.1.23 2.3.1.-] C 100981053 MBOAT7; lysophospholipid acyltransferase 7 isoform X1 K13516 MBOAT7; lysophospholipid acyltransferase 7 [EC:2.3.1.-] # AOthers B Multifunctional type B Component type ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: November 27, 2023 #
Desaturase/elongase family classification based on Hashimoto et al. (2008)