+D
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Transfer RNA Biogenesis - Rattus norvegicus (rat)
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
D 315045 Pop1; ribonucleases P/MRP protein subunit POP1 K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D 292831 Pop4; ribonuclease P protein subunit p29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D 117241 Pop5; ribonuclease P/MRP protein subunit POP5 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D 685332 Rpp30; ribonuclease P protein subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D 406230 Rpp21; ribonuclease P protein subunit p21 K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
D 361020 Rpp14; ribonuclease P protein subunit p14 K14529 RPP14; ribonuclease P protein subunit RPP14 [EC:3.1.26.5]
D 288564 Pop7; ribonuclease P protein subunit p20 K14527 RPP20; ribonuclease P/MRP protein subunit RPP20 [EC:3.1.26.5]
D 298002 Rpp25l; ribonuclease P protein subunit p25-like protein K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 315705 Rpp25; ribonuclease P protein subunit p25 K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 291317 Rpp38; ribonuclease P protein subunit p38 K14523 RPP38; ribonucleases P/MRP protein subunit RPP38 [EC:3.1.26.5]
D 291071 Rpp40; ribonuclease P protein subunit p40 isoform 1 K14530 RPP40; ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D 282826 Elac2; zinc phosphodiesterase ELAC protein 2 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 307604 Elac1; zinc phosphodiesterase ELAC protein 1 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 292306 Rnaset2; ribonuclease T2 precursor K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
D 304278 Ptcd1; pentatricopeptide repeat-containing protein 1, mitochondrial K17710 PTCD1; pentatricopeptide repeat domain-containing protein 1
C CCA adding factors
D 312616 Trnt1; CCA tRNA nucleotidyltransferase 1, mitochondrial K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
D 100911093 CCA tRNA nucleotidyltransferase 1, mitochondrial-like K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
D 312649 Tsen2; tRNA-splicing endonuclease subunit Sen2 K15322 TSEN2; tRNA-splicing endonuclease subunit Sen2 [EC:4.6.1.16]
D 292534 Tsen34; tRNA-splicing endonuclease subunit Sen34 K15323 TSEN34; tRNA-splicing endonuclease subunit Sen34 [EC:4.6.1.16]
D 289083 Tsen15; tRNA-splicing endonuclease subunit Sen15 isoform 2 K15324 TSEN15; tRNA-splicing endonuclease subunit Sen15
D 690308 Tsen54; tRNA-splicing endonuclease subunit Sen54 K15326 TSEN54; tRNA-splicing endonuclease subunit Sen54
C tRNA splicing ligase complex
D 362855 Rtcb; RNA-splicing ligase RtcB homolog K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D 301374 C9h2orf49; ashwin K15432 ASW; ashwin
D 302247 Rtraf; RNA transcription, translation and transport factor protein K15433 CGI99; RLL motif containing protein 1
D 499866 Fam98b; protein FAM98B K15434 FAM98B; protein FAM98B
D 84474 Ddx1; ATP-dependent RNA helicase DDX1 K13177 DDX1; ATP-dependent RNA helicase DDX1 [EC:5.6.2.7]
D 297885 Zbtb8os; protein archease isoform 1 K24956 ZBTB8OS; protein archease
C Other tRNA splicing factors
D 293704 Trpt1; tRNA 2'-phosphotransferase 1 K10669 TRPT1; 2'-phosphotransferase [EC:2.7.1.160]
B tRNA transport factors
C tRNA export factors
D 313163 1700009N14Rikl; uncharacterized protein LOC313163 K07936 RAN; GTP-binding nuclear protein Ran
D 84509 Ran; GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
D 751812 Rasl2-9; GTP-binding nuclear protein Ran, testis-specific isoform K07936 RAN; GTP-binding nuclear protein Ran
D 85252 Xpo1; exportin-1 K14290 XPO1; exportin-1
D 363194 Xpo5; exportin-5 K14289 XPO5; exportin-5
D 24799 Eef1a2; elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
D 171361 Eef1a1; elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
D 100360413 Eef1a1l1; elongation factor 1-alpha 1-like K03231 EEF1A; elongation factor 1-alpha
D 103691939 Eef1a1l2; elongation factor 1-alpha 1-like K03231 EEF1A; elongation factor 1-alpha
D 293684 Scyl1; N-terminal kinase-like protein K08876 SCYL1; SCY1-like protein 1
D 300077 Gtpbp1; GTP-binding protein 1 K24887 GTPBP1; GTP-binding protein 1
C tRNA import factors
D 296954 Tnpo3; transportin-3 K15436 TRPO3; transportin-3
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D 289352 Eprs1; bifunctional glutamate/proline--tRNA ligase K14163 EPRS; bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]
D 361641 Ears2; probable glutamate--tRNA ligase, mitochondrial K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D 685245 Ears2l1; glutamyl-tRNA synthetase 2-like 1 K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D 313429 Pars2; probable proline--tRNA ligase, mitochondrial precursor K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D 306804 Iars1; isoleucine--tRNA ligase, cytoplasmic K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 364070 Iars2; isoleucine--tRNA ligase, mitochondrial K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 363172 Lars2; leucine--tRNA ligase, mitochondrial K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 291624 Lars1; leucine--tRNA ligase, cytoplasmic K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 299851 Mars1; methionine--tRNA ligase, cytoplasmic K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 100911305 Mars2; methionine--tRNA ligase, mitochondrial isoform X1 K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 290868 Qars1; glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D 287191 Rars1; arginine--tRNA ligase, cytoplasmic K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 297969 Rars2; probable arginine--tRNA ligase, mitochondrial K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 292028 Kars1; lysine--tRNA ligase isoform 1 K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D 116483 Dars1; aspartate--tRNA ligase, cytoplasmic K22503 DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 304919 Dars2; aspartate--tRNA ligase, mitochondrial precursor K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 114632 Aimp1; aminoacyl tRNA synthase complex-interacting multifunctional protein 1 K15437 AIMP1; aminoacyl tRNA synthase complex-interacting multifunctional protein 1
D 288480 Aimp2; aminoacyl tRNA synthase complex-interacting multifunctional protein 2 K15438 AIMP2; aminoacyl tRNA synthase complex-interacting multifunctional protein 2
D 291057 Eef1e1; eukaryotic translation elongation factor 1 epsilon-1 K15439 EEF1E1; eukaryotic translation elongation factor 1 epsilon-1
C Other AARSs
D 292023 Aars1; alanine--tRNA ligase, cytoplasmic K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 301254 Aars2; alanine--tRNA ligase, mitochondrial K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 291556 Nars1; asparagine--tRNA ligase, cytoplasmic isoform 1 K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 293128 Nars2; probable asparagine--tRNA ligase, mitochondrial isoform 2 K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 297113 Gars1; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D 294810 Tars1; threonine--tRNA ligase 1, cytoplasmic isoform 2 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 310672 Tars2; threonine--tRNA ligase, mitochondrial K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 266975 Sars1; serine--tRNA ligase, cytoplasmic K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 292759 Sars2; serine--tRNA ligase, mitochondrial K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 361184 Cars2; probable cysteine--tRNA ligase, mitochondrial K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 293638 Cars1; cysteine--tRNA ligase, cytoplasmic K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 25009 Vars1; valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D 309596 Vars2; valine--tRNA ligase, mitochondrial precursor K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D 307491 Hars2; probable histidine--tRNA ligase, mitochondrial K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 307492 Hars1; histidine--tRNA ligase, cytoplasmic K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 306879 Fars2; phenylalanine--tRNA ligase, mitochondrial K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 288917 Farsa; phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 301544 Farsb; phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D 287924 Yars2; tyrosine--tRNA ligase, mitochondrial K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 313047 Yars1; tyrosine--tRNA ligase, cytoplasmic K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 314442 Wars1; tryptophan--tRNA ligase, cytoplasmic K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 690654 Wars2; tryptophan--tRNA ligase, mitochondrial K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D 366619 Dtd2; D-aminoacyl-tRNA deacylase 2 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 619440 Aarsd1; alanyl-tRNA editing protein Aarsd1 K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
C AARS associated factors
D 65241 Trnau1ap; tRNA selenocysteine 1-associated protein 1 isoform 1 K25102 TRNAU1AP; tRNA selenocysteine 1-associated protein 1
D 690660 Hint1; adenosine 5'-monophosphoramidase HINT1 K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D 313491 Hint2; adenosine 5'-monophosphoramidase HINT2 K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D 685311 Hint1l1; adenosine 5'-monophosphoramidase HINT1-like K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D 684427 Hint1l2; adenosine 5'-monophosphoramidase HINT1-like K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D 246769 Hint3; adenosine 5'-monophosphoramidase HINT3 isoform 1 K12150 HINT3; adenosine 5'-monophosphoramidase HINT3 [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
D 690810 Adat1; tRNA-specific adenosine deaminase 1 isoform 1 K15440 TAD1; tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
D 361453 Adat2; tRNA-specific adenosine deaminase 2 K15441 TAD2; tRNA-specific adenosine deaminase 2 [EC:3.5.4.-]
D 100125374 Adat3; probable inactive tRNA-specific adenosine deaminase-like protein 3 K15442 TAD3; tRNA-specific adenosine deaminase 3
C Dihydorouridine synthases
D 246185 Dus1l; tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like K05542 DUS1; tRNA-dihydrouridine synthase 1 [EC:1.3.1.88]
D 291978 Dus2; tRNA-dihydrouridine(20) synthase [NAD(P)+]-like K05543 DUS2; tRNA-dihydrouridine synthase 2 [EC:1.3.1.91]
D 301122 Dus3l; tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like K05544 DUS3; tRNA-dihydrouridine synthase 3 [EC:1.3.1.89]
D 366593 Dus4l; tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like K05545 DUS4; tRNA-dihydrouridine synthase 4 [EC:1.3.1.90]
C Methylthiotransferase
C Methyltransferases
D 287953 Trmt2a; tRNA (uracil-5-)-methyltransferase homolog A K15332 TRMT2A; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.-]
D 503462 Trmt2b; LOW QUALITY PROTEIN: tRNA (uracil-5-)-methyltransferase homolog B K15331 TRMT2B; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D 679346 Tarbp1; probable methyltransferase TARBP1 isoform X1 K15333 TRM3; tRNA guanosine-2'-O-methyltransferase [EC:2.1.1.34]
D 361191 Nsun2; RNA cytosine C(5)-methyltransferase NSUN2 K15335 NSUN2; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.203]
D 100360437 Nsun3; NOP2/Sun RNA methyltransferase 3 K21969 NSUN3; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.-]
D 307148 Nsun6; tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 K21971 NSUN6; methyltransferase NSUN6 [EC:2.1.1.-]
D 362754 Trmt5; tRNA (guanine(37)-N1)-methyltransferase isoform 1 K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D 314462 Trmt61a; tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D 311441 Trmt6; tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 K03256 TRM6; tRNA (adenine58-N1)-methyltransferase non-catalytic subunit
D 363450 Ftsj1; putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase K14864 FTSJ1; tRNA (cytidine32/guanosine34-2'-O)-methyltransferase [EC:2.1.1.205]
D 679091 Mettl1; tRNA (guanine-N(7)-)-methyltransferase isoform 1 K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D 363687 Mettl2; methyltransferase-like protein 2A K24974 METTL2; tRNA N(3)-methylcytidine methyltransferase METTL2 [EC:2.1.1.-]
D 290564 Mettl6; tRNA N(3)-methylcytidine methyltransferase METTL6 K00599 METTL6; tRNA N(3)-methylcytidine methyltransferase METTL6 [EC:2.1.1.-]
D 366783 Alkbh8; alkylated DNA repair protein alkB homolog 8 K10770 ALKBH8; alkylated DNA repair protein alkB homolog 8 [EC:1.14.11.- 2.1.1.229]
D 295496 Trmt10a; tRNA methyltransferase 10 homolog A K15445 TRMT10; tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221]
D 298081 Trmt10b; tRNA methyltransferase 10 homolog B K15445 TRMT10; tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221]
D 378794 Trmt11; tRNA (guanine(10)-N2)-methyltransferase homolog K15430 TRM11; tRNA (guanine10-N2)-methyltransferase [EC:2.1.1.214]
D 499697 Trmt13; tRNA:m(4)X modification enzyme TRM13 homolog K15446 TRM13; tRNA:m4X modification enzyme [EC:2.1.1.225]
D 305443 Trmt44; probable tRNA (uracil-O(2)-)-methyltransferase K15447 TRM44; tRNASer (uridine44-2'-O)-methyltransferase [EC:2.1.1.211]
D 690032 Wdr4; tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 K15443 TRM82; tRNA (guanine-N(7)-)-methyltransferase subunit TRM82
D 293700 Trmt112; multifunctional methyltransferase subunit TRM112-like protein K15448 TRM112; multifunctional methyltransferase subunit TRM112
D 291324 Trdmt1; tRNA (cytosine(38)-C(5))-methyltransferase K15336 TRDMT1; tRNA (cytosine38-C5)-methyltransferase [EC:2.1.1.204]
D 298072 Trmo; tRNA (adenine(37)-N6)-methyltransferase K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D 304423 Tyw1; tRNA wybutosine-synthesizing protein 1 homolog K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D 314999 Trmt12; tRNA wybutosine-synthesizing protein 2 homolog K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D 296098 Lcmt2; tRNA wybutosine-synthesizing protein 4 K15451 PPM2; tRNA wybutosine-synthesizing protein 4 [EC:2.1.1.290 2.3.1.231]
D 301419 Tyw5; tRNA wybutosine-synthesizing protein 5 K18066 TYW5; tRNA wybutosine-synthesizing protein 5 [EC:1.14.11.42]
D 363001 Bcdin3d; RNA 5'-monophosphate methyltransferase K25191 BCDIN3D; RNA 5'-monophosphate methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D 304567 Pus1; pseudouridylate synthase 1 homolog K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D 315554 Pus3; tRNA pseudouridine(38/39) synthase K01855 PUS3; tRNA pseudouridine38/39 synthase [EC:5.4.99.45]
D 361775 Trub1; pseudouridylate synthase TRUB1 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D 315264 Pus7l; pseudouridylate synthase PUS7L K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D 296751 Pus7; pseudouridylate synthase 7 homolog K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D 305583 Pus10; tRNA pseudouridine synthase Pus10 isoform 2 K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
D 315550 Rpusd4; pseudouridylate synthase RPUSD4, mitochondrial K22538 RPUSD4; mitochondrial RNA pseudouridine synthase RPUSD4 [EC:5.4.99.-]
C Thiolation factors
D 362976 Trmu; mitochondrial tRNA-specific 2-thiouridylase 1 isoform 1 K21027 TRMU; tRNA-5-taurinomethyluridine 2-sulfurtransferase [EC:2.8.1.14]
D 292847 Ctu1; cytoplasmic tRNA 2-thiolation protein 1 K14168 CTU1; cytoplasmic tRNA 2-thiolation protein 1 [EC:2.7.7.-]
D 292069 Ctu2; cytoplasmic tRNA 2-thiolation protein 2 K14169 CTU2; cytoplasmic tRNA 2-thiolation protein 2
D 84594 Nfs1; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D 311840 Urm1; ubiquitin-related modifier 1 K12161 URM1; ubiquitin related modifier 1
D 311655 Mocs3; adenylyltransferase and sulfurtransferase MOCS3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C KEOPS/EKC complex
D 362272 Tp53rkb; TP53-regulating kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D 685619 Tp53rka; TP53-regulating kinase (p53-related protein kinase) (Nori-2) K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D 314548 Osgepl1; tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial isoform 1 K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D 290028 Osgep; tRNA N6-adenosine threonylcarbamoyltransferase K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D 297411 Tprkb; EKC/KEOPS complex subunit Tprkb K15901 TPRKB; EKC/KEOPS complex subunit TPRKB/CGI121
D 293863 Lage3; EKC/KEOPS complex subunit LAGE3 K15902 LAGE3; EKC/KEOPS complex subunit LAGE3/PCC1
D 100233176 Gon7; EKC/KEOPS complex subunit GON7 isoform 1 K15903 GON7; EKC/KEOPS complex subunit GON7
C Elongator complex
D 140934 Elp1; elongator complex protein 1 K11373 ELP1; elongator complex protein 1
D 307545 Elp2; elongator complex protein 2 K11374 ELP2; elongator complex protein 2
D 100362548 Elp3; elongator complex protein 3 isoform X1 K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D 687694 Elp4; elongator complex protein 4 K11375 ELP4; elongator complex protein 4
D 287446 Elp5; elongator complex protein 5 K11376 ELP5; elongator complex protein 5
D 363150 Elp6; elongator complex protein 6 K11377 ELP6; elongator complex protein 6
C Elongator related proteins
D 680594 Dph3; diphthamide biosynthesis protein 3 K15455 DPH3; diphthamide biosynthesis protein 3
D 685656 Kti12; protein KTI12 homolog K15456 KTI12; protein KTI12
C Other tRNA modification factors
D 319113 Yrdc; threonylcarbamoyl-AMP synthase precursor K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D 362586 Trit1; tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D 290633 Gtpbp3; tRNA modification GTPase GTPBP3, mitochondrial precursor K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D 300852 Mto1; protein MTO1 homolog, mitochondrial K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D 64016 Qtrt1; queuine tRNA-ribosyltransferase catalytic subunit 1 K00777 QTRT1; queuine tRNA-ribosyltransferase catalytic subunit [EC:2.4.2.64]
D 288364 Qtrt2; queuine tRNA-ribosyltransferase accessory subunit 2 K15407 QTRT2; queuine tRNA-ribosyltransferase accessory subunit
D 291314 Sephs1; selenide, water dikinase 1 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 308993 Sephs2; selenide, water dikinase 2 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 309041 Thumpd1; THUMP domain-containing protein 1 K06963 TAN1; tRNA acetyltransferase TAN1
D 303067 Thg1l; probable tRNA(His) guanylyltransferase K10761 THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79]
D 293526 Ate1; arginyl-tRNA--protein transferase 1 isoform 3 K00685 ATE1; arginyl-tRNA---protein transferase [EC:2.3.2.8]
D 363146 Dalrd3; DALR anticodon-binding domain-containing protein 3 K24973 DALRD3; DALR anticodon-binding domain-containing protein 3
B tRNA degradation factors
C TRAMP complex
D 298086 Zcchc7; zinc finger CCHC domain-containing protein 7 K12597 AIR1_2; protein AIR1/2
D 365668 Mtrex; exosome RNA helicase MTR4 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
C Rapid tRNA decay (RTD) pathway factors
D 300944 Xrn1; 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
D 362229 Xrn2; 5'-3' exoribonuclease 2 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D 64473 Bpnt1; 3'(2'),5'-bisphosphate nucleotidase 1 K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
D 305843 Ang; angiogenin precursor K16631 ANG; angiogenin [EC:3.1.27.-]
D 497229 Ang2; angiogenin, ribonuclease A family, member 2 precursor K16631 ANG; angiogenin [EC:3.1.27.-]
D 303378 Slfn9; schlafen family member 13 K24459 SLFN13; schlafen family member 13 [EC:3.1.-.-]
#
AProkaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D 282826 Elac2; zinc phosphodiesterase ELAC protein 2 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 307604 Elac1; zinc phosphodiesterase ELAC protein 1 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 292306 Rnaset2; ribonuclease T2 precursor K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
C CCA adding factors
D 312616 Trnt1; CCA tRNA nucleotidyltransferase 1, mitochondrial K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
D 100911093 CCA tRNA nucleotidyltransferase 1, mitochondrial-like K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D 362855 Rtcb; RNA-splicing ligase RtcB homolog K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D 363172 Lars2; leucine--tRNA ligase, mitochondrial K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 291624 Lars1; leucine--tRNA ligase, cytoplasmic K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 313429 Pars2; probable proline--tRNA ligase, mitochondrial precursor K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D 287924 Yars2; tyrosine--tRNA ligase, mitochondrial K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 313047 Yars1; tyrosine--tRNA ligase, cytoplasmic K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 314442 Wars1; tryptophan--tRNA ligase, cytoplasmic K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 690654 Wars2; tryptophan--tRNA ligase, mitochondrial K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 294810 Tars1; threonine--tRNA ligase 1, cytoplasmic isoform 2 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 310672 Tars2; threonine--tRNA ligase, mitochondrial K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 306804 Iars1; isoleucine--tRNA ligase, cytoplasmic K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 364070 Iars2; isoleucine--tRNA ligase, mitochondrial K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 292028 Kars1; lysine--tRNA ligase isoform 1 K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D 292023 Aars1; alanine--tRNA ligase, cytoplasmic K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 301254 Aars2; alanine--tRNA ligase, mitochondrial K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 25009 Vars1; valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D 309596 Vars2; valine--tRNA ligase, mitochondrial precursor K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D 299851 Mars1; methionine--tRNA ligase, cytoplasmic K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 100911305 Mars2; methionine--tRNA ligase, mitochondrial isoform X1 K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 266975 Sars1; serine--tRNA ligase, cytoplasmic K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 292759 Sars2; serine--tRNA ligase, mitochondrial K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 304919 Dars2; aspartate--tRNA ligase, mitochondrial precursor K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 361184 Cars2; probable cysteine--tRNA ligase, mitochondrial K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 293638 Cars1; cysteine--tRNA ligase, cytoplasmic K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 361641 Ears2; probable glutamate--tRNA ligase, mitochondrial K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D 685245 Ears2l1; glutamyl-tRNA synthetase 2-like 1 K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D 290868 Qars1; glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D 287191 Rars1; arginine--tRNA ligase, cytoplasmic K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 297969 Rars2; probable arginine--tRNA ligase, mitochondrial K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 306879 Fars2; phenylalanine--tRNA ligase, mitochondrial K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 288917 Farsa; phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 301544 Farsb; phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D 307491 Hars2; probable histidine--tRNA ligase, mitochondrial K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 307492 Hars1; histidine--tRNA ligase, cytoplasmic K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 291556 Nars1; asparagine--tRNA ligase, cytoplasmic isoform 1 K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 293128 Nars2; probable asparagine--tRNA ligase, mitochondrial isoform 2 K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
C Trans-editing factors
D 366619 Dtd2; D-aminoacyl-tRNA deacylase 2 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 619440 Aarsd1; alanyl-tRNA editing protein Aarsd1 K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferases
C Methyltransferases
D 679091 Mettl1; tRNA (guanine-N(7)-)-methyltransferase isoform 1 K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D 290633 Gtpbp3; tRNA modification GTPase GTPBP3, mitochondrial precursor K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D 298072 Trmo; tRNA (adenine(37)-N6)-methyltransferase K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D 304567 Pus1; pseudouridylate synthase 1 homolog K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D 361775 Trub1; pseudouridylate synthase TRUB1 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D 315264 Pus7l; pseudouridylate synthase PUS7L K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D 296751 Pus7; pseudouridylate synthase 7 homolog K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D 84594 Nfs1; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
D 362272 Tp53rkb; TP53-regulating kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D 685619 Tp53rka; TP53-regulating kinase (p53-related protein kinase) (Nori-2) K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D 314548 Osgepl1; tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial isoform 1 K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D 290028 Osgep; tRNA N6-adenosine threonylcarbamoyltransferase K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
C Other tRNA modification factors
D 300852 Mto1; protein MTO1 homolog, mitochondrial K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D 362586 Trit1; tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D 29498 Pts; 6-pyruvoyl tetrahydrobiopterin synthase isoform 2 K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D 291314 Sephs1; selenide, water dikinase 1 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 308993 Sephs2; selenide, water dikinase 2 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 319113 Yrdc; threonylcarbamoyl-AMP synthase precursor K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
B tRNA degradation factors
C 360992 Pnpt1; polyribonucleotide nucleotidyltransferase 1, mitochondrial K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C 293052 Isg20; interferon-stimulated gene 20 kDa protein K12579 ISG20; interferon-stimulated gene 20 kDa protein [EC:3.1.13.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024