+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Staphylococcus aureus subsp. aureus Newman</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
C    NWMN_0139 hsdR; type-I restriction-modification system restriction endonuclease subunit	K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] 
C    NWMN_0399 hsdS; type I restriction modification system, site specificity determination subunit	K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] 
C    NWMN_1699 hsdS; type I restriction modification system, site specificity determination subunit	K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] 
C    NWMN_1700 hsdM; type I restriction-modification system, methyltransferase subunit	K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] 
C    NWMN_0398 hsdM; type I restriction-modification system, methyltransferase subunit	K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] 
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      NWMN_1606 conserved hypothetical protein	K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] 
B  Type III R-M system
B  Type IV R-M system
C    NWMN_1901 phage HNH endonuclease	K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] 
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
D      NWMN_1974 PemK family of DNA-binding protein	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
C    YafQ-dinJ
C    YoeB-YefM
D      NWMN_2307 addiction module toxin Txe/YoeB family protein	K19158 yoeB; toxin YoeB [EC:3.1.-.-] 
D      NWMN_2355 stbD; prevent-host-death protein	K19159 yefM; antitoxin YefM 
C    HipA-HipB
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
C    Doc-Phd
C    HigB-HigA
C    MqsR-MqsA
C    VapC-VapB
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
C    BC_0920-BC_0921
C    Type II TA system related factors
D      NWMN_1096 ftsZ; cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      NWMN_1268 parC; DNA topoisomerase IV, A subunit	K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] 
D      NWMN_1267 parE; DNA topoisomerase IV, B subunit	K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    NWMN_1610 aminotransferase, class V	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
C    NWMN_1524 aminotransferase, class V	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023