+C Peptidases and inhibitors KO
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Peptidases and Inhibitors - Staphylococcus aureus subsp. aureus MW2 (CA-MRSA)
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AAspartic peptidases
B Family A1: pepsin family
B Family A2: retropepsin family
B Family A5: thermopsin family
B Family A8: signal peptidase II family
C MW1079 lsp; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
B Family A22: presenilin family
B Family A24: type IV prepilin peptidase family
B Family A25: gpr protease family
B Family A26: omptin family
B Family A28
B Family A31: HybD endopeptidase family
B Family A36
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ACysteine peptidases
B Family C1: papain family
B Family C2: calpain family
B Family C3: picornain family
B Family C4: NIa protease family
B Family C5
B Family C9
B Family C10: streptopain family
B Family C11: clostripain family
B Family C12: ubiquitin C-terminal hydrolase family
B Family C13: legumain family
B Family C14: caspase family
B Family C15: pyroglutamyl peptidase I family
C MW2610 pcp; pyrrolidone-carboxylate peptidase K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3]
B Family C16
B Family C19: ubiquitin-specific protease family
B Family C25: gingipain family
B Family C26: gamma-glutamyl hydrolase family
C MW0367 guaA; GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
B Family C27
B Family C30
B Family C37
B Family C39
B Family C40
B Family C44
C MW0953 purF; phosphoribosylpyrophosphate amidotransferase PurF K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C MW0426 gltB; glutamate synthase large subunit K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
C MW2080 glmS; glucosamine-fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
B Family C45
B Family C46: hedgehog family
B Family C47: staphopain family
C MW1850 Staphopain Cysteine Proteinase K08258 sspB2; staphopain A [EC:3.4.22.48]
C MW0931 sspB; cysteine protease precursor K13715 sspB; staphopain B [EC:3.4.22.-]
B Family C48: Ulp1 endopeptidase family
B Family C50: separase family
B Family C54: Aut2 peptidase family
B Family C55: YopJ protease family
B Family C56: PfpI endopeptidase family
C MW0506 conserved hypothetical protein K05523 hchA; D-lactate dehydratase / protein deglycase [EC:4.2.1.130 3.5.1.124]
C MW1815 conserved hypothetical protein K05520 yhbO; deglycase [EC:3.5.1.124]
B Family C57: vaccinia virus I7 peptidase family
B Family C58
B Family C59
C MW0251 ORFID:MW0251; hypothetical protein, similar to penicillin amidase (EC 3.5.1.11) V K24041 yxeI; penicillin V amidase [EC:3.5.1.11]
B Family C60
C MW2448 srtA; sortase K07284 srtA; sortase A [EC:3.4.22.70]
C MW1017 srtB; NPQTN specific sortase B K08600 srtB; sortase B [EC:3.4.22.71]
B Family C63
B Family C64
B Family C65
B Family C67
B Family C69
B Family C70
B Family C75
C MW1960 agrB; accessory gene regulator B K07813 agrB; accessory gene regulator B
B Family C76
B Family C78
B Family C79
B Family C82
B Family C83
B Family C85
B Family C86
B Family C88
B Family C89
B Family C97
B Family C98
B Family C110
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AGlutamic peptidases
B Family G1
B Family G4
B Family G5: prenyl protease 2 family
C MW1955 conserved hypothetical protein K07052 K07052; CAAX protease family protein
C MW1720 hypothetical protein K07052 K07052; CAAX protease family protein
C MW0910 hypothetical protein K07052 K07052; CAAX protease family protein
C MW2234 ORFID:MW2234; hypothetical protein, similar to protein of pXO2-46 K07052 K07052; CAAX protease family protein
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AMetallo peptidases
B Family M1
B Family M2
B Family M3
C MW0882 ORFID:MW0882; thimet oligopeptidase homologue K08602 pepF; oligoendopeptidase F [EC:3.4.24.-]
B Family M4: thermolysin family
C MW2558 aur; zinc metalloproteinase aureolysin K01401 aur; aureolysin [EC:3.4.24.29]
B Family M5: mycolysin family
B Family M6: immune inhibitor A family
B Family M7: snapalysin family
B Family M8: leishmanolysin family
B Family M9
B Family M10
B Family M12: astacin/adamalysin family
B Family M13: neprilysin family
B Family M14: carboxypeptidase A family
B Family M15: zinc D-Ala-D-Ala carboxypeptidase family
B Family M16: pitrilysin family
B Family M17: leucyl aminopeptidase family
C MW0824 ampA; probable cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
B Family M18
B Family M19: membrane dipeptidase family
B Family M20
C MW1694 ORFID:MW1694; Xaa-His dipeptidase homolog K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
C MW1943 ORFID:MW1943; hypothetical protein, similar to succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
C MW0705 pepT; aminotripeptidase K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]
C MW1465 ORFID:MW1465; hypothetical protein, similar to tripeptidase K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]
B Family M23
C MW0188 ORFID:MW0188; hypothetical protein, similar to lysostaphin precursor K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-]
C MW0252 lytM; peptidoglycan hydrolase K08259 lytM; lysostaphin [EC:3.4.24.75]
B Family M24
C MW1828 map; methionyl aminopeptidase map K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C MW1651 ORFID:MW1651; Xaa-Pro dipeptidase homolog K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]
C MW1482 Xaa-Pro dipeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
B Family M26
B Family M27
B Family M28: aminopeptidase Y family
B Family M29: aminopeptidase T family
C MW1819 ampS; aminopeptidase ampS K19689 ampS; aminopeptidase [EC:3.4.11.-]
B Family M32: carboxypeptidase Taq family
B Family M34: anthrax lethal factor family
B Family M35: deuterolysin family
B Family M36: fungalysin family
B Family M38: beta-aspartyl dipeptidase family
B Family M41: FtsH endopeptidase family
C MW0466 ftsH; cell-division protein K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
B Family M42: glutamyl aminopeptidase family
C MW1688 ORFID:MW1688; endo-1,4-beta-glucanase homolog K01261 pepA; glutamyl aminopeptidase [EC:3.4.11.7]
C MW1253 ORFID:MW1253; hypothetical protein, similar to glucanase K01269 yhfE; aminopeptidase [EC:3.4.11.-]
B Family M43: cytophagalysin family
B Family M44
B Family M48: Ste24 endopeptidase family
B Family M49: dipeptidyl-peptidase III family
B Family M50: S2P protease family
C MW1145 conserved hypotehtical protein K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
B Family M54
B Family M55: DppA aminopeptidase family
B Family M56
C MW0032 truncated methicillin resistance protein MecR1 K02547 mecR1; methicillin resistance protein
B Family M67
B Family M72
B Family M73
B Family M74
B Family M80
B Family M82
C MW0212 hypothetical protein K24131 prsW; protease PrsW [EC:3.4.-.-]
B Family M85
B Family M88
B Family M90
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AAsparagine peptide lyases
B Family N1
B Family N8
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AMixed peptidases
B Family P1: DmpA aminopeptidase family
B Family P2
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ASerine peptidases
B Family S1: chymotrypsin family
C MW0932 sspA; serine protease; V8 protease; glutamyl endopeptidase K01318 sspA; glutamyl endopeptidase [EC:3.4.21.19]
C MW1752 splF; serine protease SplF K01318 sspA; glutamyl endopeptidase [EC:3.4.21.19]
C MW1755 splA; serine protease SplA K01318 sspA; glutamyl endopeptidase [EC:3.4.21.19]
C MW1670 ORFID:MW1670; hypothetical protein, similar to serine proteinase Do, heat-shock protein htrA K04771 degP; serine protease Do [EC:3.4.21.107]
B Family S3: togavirin family
B Family S6
B Family S7: flavivirin family
B Family S8: subtilisin family
C MW1761 bsaP; ORFID:MW1761; hypothetical protein, similar to EPIDERMIN LEADER PEPTIDE PROCESSING SERINE PROTEASE EPIP PRECURSOR [Genomic island nu Sa beta2] K20486 nisP; lantibiotic leader peptide-processing serine protease [EC:3.4.21.-]
B Family S9: prolyl oligopeptidase family
B Family S10
B Family S11: D-Ala-D-Ala carboxypeptidase A family
C MW0604 pbp4; penicillin binding protein 4 K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
B Family S12: D-Ala-D-Ala carboxypeptidase B family
B Family S13: D-Ala-D-Ala peptidase C family
B Family S14: ClpP endopeptidase family
C MW0730 clpP; ATP-dependent Clp protease proteolyticsubunit homologue; ORFID:MW0730 K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
B Family S15
B Family S16: lon protease family
B Family S21: assemblin family
B Family S24: LexA family
C MW1226 lexA; SOS regulatory LexA protein K01356 lexA; repressor LexA [EC:3.4.21.88]
B Family S26: signal peptidase I family
C MW0846 spsA; type-I signal peptidase K03100 lepB; signal peptidase I [EC:3.4.21.89]
C MW0847 spsB; type-1 signal peptidase 1B K03100 lepB; signal peptidase I [EC:3.4.21.89]
B Family S28
B Family S31
B Family S32
B Family S33
B Family S41: C-terminal processing peptidase family
C MW1310 ctpA; probable carboxy-terminal processing proteinase ctpA K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
B Family S45
B Family S49: protease IV family
B Family S50
B Family S51
B Family S53
B Family S54: Rhomboid family
C MW1501 conserved hypothetical protein K19225 gluP; rhomboid protease GluP [EC:3.4.21.105]
B Family S55: SpoIVB peptidase family
B Family S62
B Family S66
B Family S77: phage prohead processing peptidase family
B Family S78
C MW1905 hypothetical protein K06904 GP4; Escherichia/Staphylococcus phage prohead protease
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AThreonine peptidases
B Family T1: proteasome family
C MW1136 clpQ; heat shock protein HslV K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
B Family T2
B Family T3: gamma-glutamyltransferase family
C MW0185 ORFID:MW0185; hypothetical protein, similar to gamma-glutamyltranspeptidase precursor K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
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APeptidases of unknown catalytic type
B Family U32
C MW1562 ORFID:MW1562; hypothetical protein, similar to protease K08303 prtC; U32 family peptidase [EC:3.4.-.-]
C MW1563 ORFID:MW1563; hypothetical protein, similar to protease K08303 prtC; U32 family peptidase [EC:3.4.-.-]
B Family U62
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APeptidase inhibitors
B Family I1: Kazal family
B Family I2: Kunitz - BPTI family
B Family I4: serpin family
B Family I11: ecotin family
B Family I17: WAP-type family
B Family I25: cystatin family
B Family I27: calpastatin family
B Family I32: IAP family
B Family I34: IA3 family
B Family I35: timp family
B Family I39: alpha2M family
B Family I47: latexin family
B Family I49: proSAAS family
B Family I51: IC family
B Family I57: staphostatin B family
C MW0930 sspC; cysteine protease K23597 sspC; staphostatin B
B Family I63
B Family I80
B Family I87
B Family I93
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 13, 2023
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Classification taken and modified from MEROPS