+C Kinase KO
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Protein Kinases - Saccharomyces cerevisiae (budding yeast)
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ASerine/threonine kinases: AGC group
B PKA family
C YJL164C TPK1; cAMP-dependent protein kinase catalytic subunit TPK1 K04345 PKA; protein kinase A [EC:2.7.11.11]
C YPL203W TPK2; cAMP-dependent protein kinase catalytic subunit TPK2 K04345 PKA; protein kinase A [EC:2.7.11.11]
C YKL166C TPK3; cAMP-dependent protein kinase catalytic subunit TPK3 K04345 PKA; protein kinase A [EC:2.7.11.11]
B PKG family
B PKC family [OT]
C YBL105C PKC1; protein kinase C K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
B PKN family
B AUR family [OT]
C YPL209C IPL1; aurora kinase K08850 AURKX; aurora kinase, other [EC:2.7.11.1]
B PDK1 family
C YDR466W PKH3; protein kinase PKH3 K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
C YDR490C PKH1; serine/threonine protein kinase PKH1 K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
C YOL100W PKH2; serine/threonine protein kinase PKH2 K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
B AKT/PKB family
C YHR205W SCH9; serine/threonine protein kinase SCH9 K19800 SCH9; serine/threonine protein kinase SCH9 [EC:2.7.11.1]
B SGK family [OT]
C YMR104C YPK2; putative protein kinase YPK2 K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
C YKL126W YPK1; serine/threonine protein kinase YPK1 K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
B RSK family [OT]
C YBR028C YPK3; putative protein kinase YPK3 K22008 PSK1; serine/threonine-protein kinase Psk1 [EC:2.7.11.1]
B NDR family
B MAST family [OT]
C YFL033C RIM15; protein kinase RIM15 K12767 RIM15; serine/threonine-protein kinase RIM15 [EC:2.7.11.36]
B YANK family
B DMPK family [OT]
B GRK family [OT]
B Other
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ASerine/threonine kinases: CAMK group
B CAMK1 family [OT]
C YOL016C CMK2; calmodulin-dependent protein kinase CMK2 K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
C YFR014C CMK1; calmodulin-dependent protein kinase CMK1 K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
B CAMK2 family
B CAMKL family
C YBR274W CHK1; serine/threonine protein kinase CHK1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
C YDR477W SNF1; AMP-activated serine/threonine-protein kinase catalytic subunit SNF1 K12761 SNF1; carbon catabolite-derepressing protein kinase [EC:2.7.11.1]
C YCL024W KCC4; serine/threonine protein kinase K18639 KCC4; serine/threonine-protein kinase KCC4 [EC:2.7.11.1]
C YDR507C GIN4; protein kinase GIN4 K06668 GIN4; serine/threonine-protein kinase GIN4 [EC:2.7.11.-]
C YKL101W HSL1; protein kinase HSL1 K02515 HSL1; serine/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-]
C YDR122W KIN1; serine/threonine protein kinase KIN1 K19852 KIN1_2; serine/threonine protein kinase KIN1/2 [EC:2.7.11.1]
C YLR096W KIN2; serine/threonine protein kinase KIN2 K19852 KIN1_2; serine/threonine protein kinase KIN1/2 [EC:2.7.11.1]
B DAPK family
B DCAMKL family
B MAPKAPK family [OT]
B MLCK family
B PHK family
B PIM family [OT]
B PKD family
B PSK family
B RAD53 family
C YDL101C DUN1; serine/threonine protein kinase DUN1 K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
C YOR351C MEK1; serine/threonine protein kinase MEK1 K12776 MEK1; meiosis-specific serine/threonine-protein kinase MEK1 [EC:2.7.11.1]
B Trio family [OT]
B TSSK family
B CDPK family
B CASK family
B Trbl family
B Other
C YLR248W RCK2; serine/threonine protein kinase RCK2 K23785 RCK2; serine/threonine-protein kinase RCK2 [EC:2.7.11.1]
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ASerine/threonine kinases: CK1 group
B CK1 family [OT]
C YNL154C YCK2; serine/threonine protein kinase YCK2 K02218 CSNK1; casein kinase 1 [EC:2.7.11.1]
C YHR135C YCK1; serine/threonine protein kinase YCK1 K02218 CSNK1; casein kinase 1 [EC:2.7.11.1]
C YER123W YCK3; casein kinase YCK3 K19830 YCK3; casein kinase I homolog 3 [EC:2.7.11.1]
C YPL204W HRR25; serine/threonine protein kinase HRR25 K14758 HRR25; casein kinase I homolog HRR25 [EC:2.7.11.1]
B TTBK family
B VRK family
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ASerine/threonine kinases: CMGC group
B CDK family
C YDL108W KIN28; TFIIH complex serine/threonine-protein kinase subunit KIN28 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
C YPL042C SSN3; cyclin-dependent serine/threonine protein kinase SSN3 K02208 CDK8_11; cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23]
C YPR161C SGV1; cyclin-dependent serine/threonine protein kinase SGV1 K15562 BUR1; serine/threonine-protein kinase BUR1 [EC:2.7.11.22 2.7.11.23]
C YKL139W CTK1; cyclin-dependent serine/threonine protein kinase CTK1 K00916 CTK1; CTD kinase subunit alpha [EC:2.7.11.22 2.7.11.23]
B MAPK family [OT]
C YBL016W FUS3; mitogen-activated serine/threonine-protein kinase FUS3 K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
C YGR040W KSS1; mitogen-activated serine/threonine-protein kinase KSS1 K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
C YHR030C SLT2; mitogen-activated serine/threonine-protein kinase SLT2 K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
C YLR113W HOG1; mitogen-activated protein kinase HOG1 K04441 P38; p38 MAP kinase [EC:2.7.11.24]
C YPR054W SMK1; mitogen-activated protein kinase SMK1 K08293 SMK1; sporulation-specific mitogen-activated protein kinase SMK1 [EC:2.7.11.24]
B GSK family [OT]
C YMR139W RIM11; serine/threonine protein kinase RIM11 K12766 MDS1; serine/threonine-protein kinase MDS1/RIM11 [EC:2.7.11.1]
B CLK family
B CDKL family
B DYRK family [OT]
C YJL141C YAK1; serine/threonine protein kinase YAK1 K18670 YAK1; dual specificity protein kinase YAK1 [EC:2.7.12.1]
B RCK family [OT]
C YJL106W IME2; protein kinase IME2 K12765 IME2; meiosis induction protein kinase IME2/SME1 [EC:2.7.11.1]
B SRPK family [OT]
C YMR216C SKY1; serine/threonine protein kinase SKY1 K08832 SRPK3; serine/threonine-protein kinase SRPK3 [EC:2.7.11.1]
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ASerine/threonine kinases: STE group
B STE7 family
C YOR231W MKK1; mitogen-activated protein kinase kinase MKK1 K08294 MKK1_2; mitogen-activated protein kinase kinase [EC:2.7.12.2]
C YPL140C MKK2; putative mitogen-activated protein kinase kinase MKK2 K08294 MKK1_2; mitogen-activated protein kinase kinase [EC:2.7.12.2]
C YDL159W STE7; mitogen-activated protein kinase kinase STE7 K11226 STE7; mitogen-activated protein kinase kinase [EC:2.7.12.2]
C YJL128C PBS2; mitogen-activated protein kinase kinase PBS2 K11227 PBS2; mitogen-activated protein kinase kinase [EC:2.7.12.2]
B STE20 family
C YHL007C STE20; mitogen-activated protein kinase kinase kinase kinase STE20 K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
C YOL113W SKM1; putative serine/threonine protein kinase SKM1 K19833 CLA4; serine/threonine-protein kinase CLA4 [EC:2.7.11.1]
C YNL298W CLA4; serine/threonine protein kinase CLA4 K19833 CLA4; serine/threonine-protein kinase CLA4 [EC:2.7.11.1]
C YDR523C SPS1; putative serine/threonine protein kinase SPS1 K12771 SPS1; sporulation-specific protein 1 [EC:2.7.11.1]
B STE11 family
C YLR362W STE11; mitogen-activated protein kinase kinase kinase STE11 K11228 STE11; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
B Other
C YJL095W BCK1; mitogen-activated protein kinase kinase kinase BCK1 K11229 BCK1; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
C YCR073C SSK22; mitogen-activated protein kinase kinase kinase SSK22 K11230 SSK2; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
C YNR031C SSK2; mitogen-activated protein kinase kinase kinase SSK2 K11230 SSK2; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
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ASerine/threonine kinases: TKL group
B IRAK family
B LISK family [OT]
B LRRK family
B MLK family
B RAF family [OT]
B RIPK family [OT]
B Other
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ASerine/threonine kinases: Other
B RGC family [OT]
B BUB family
C YGR188C BUB1; protein kinase BUB1 K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
B Bud32 family
C YGR262C BUD32; serine/threonine protein kinase BUD32 K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
B CAMKK family
B CDC7 family
C YDL017W CDC7; serine/threonine protein kinase CDC7 K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
B CK2 family
C YIL035C CKA1; casein kinase 2 catalytic subunit CKA1 K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
C YOR061W CKA2; casein kinase 2 catalytic subunit CKA2 K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
B Haspin family
C YBL009W ALK2; protein kinase ALK2 K16315 GSG2; serine/threonine-protein kinase haspin [EC:2.7.11.1]
C YGL021W ALK1; protein kinase ALK1 K16315 GSG2; serine/threonine-protein kinase haspin [EC:2.7.11.1]
B IKK family [OT]
B IRE family
C YHR079C IRE1; bifunctional endoribonuclease/protein kinase IRE1 K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
B MOS family
B NAK family [OT]
C YIL095W PRK1; serine/threonine protein kinase PRK1 K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
C YNL020C ARK1; serine/threonine protein kinase ARK1 K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
C YPL236C ENV7; putative serine/threonine protein kinase ENV7 K08856 STK16; serine/threonine kinase 16 [EC:2.7.11.1]
B NEK family
C YAR018C KIN3; serine/threonine protein kinase KIN3 K20872 NEK2; serine/threonine-protein kinase Nek2 [EC:2.7.11.1]
B NKF1 family
B NKF2 family
B NKF3 family
B NKF4 family
B NKF5 family
B NRBP family
B PEK family [OT]
C YDR283C GCN2; serine/threonine-protein kinase GCN2 K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
B PLK family [OT]
B SCY1 family [OT]
C YOR112W CEX1; Cex1p K08876 SCYL1; SCY1-like protein 1
C YGL083W SCY1; Scy1p K17541 SCYL2; SCY1-like protein 2
B Slob family
B TBCK family
B TLK family
B TOPK family
B TTK family
C YDL028C MPS1; serine/threonine/tyrosine protein kinase MPS1 K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
B ULK family [OT]
C YGL180W ATG1; serine/threonine protein kinase ATG1 K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
B VPS15 family
C YBR097W VPS15; ubiquitin-binding serine/threonine protein kinase VPS15 K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
B WEE family
B Wnk family
B ABC1 family
C YGL119W COQ8; protein kinase COQ8 K08869 ADCK; aarF domain-containing kinase
C YLR253W CQD2; Cqd2p K08869 ADCK; aarF domain-containing kinase
C YPL109C CQD1; Cqd1p K08869 ADCK; aarF domain-containing kinase
B Alpha family [OT]
B BCR family
B BRD family [OT]
B FAST family
B G11 family
B H11 family
B PDHK family [OT]
C YIL042C PKP1; protein kinase PKP1 K12077 PDK1; pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]
C YGL059W PKP2; protein kinase PKP2 K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
B PIKK family [OT]
C YBL088C TEL1; DNA-binding protein kinase TEL1 K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
C YJR066W TOR1; phosphatidylinositol kinase-related protein kinase TOR1 K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
C YKL203C TOR2; phosphatidylinositol kinase-related protein kinase TOR2 K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
C YHR099W TRA1; histone acetyltransferase TRA1 K08874 TRRAP; transformation/transcription domain-associated protein
B RIO family [OT]
C YOR119C RIO1; protein kinase RIO1 K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
C YNL207W RIO2; protein kinase RIO2 K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
B TAF1 family
B TIF1 family [OT]
B Other
C YKL048C ELM1; serine/threonine protein kinase ELM1 K16314 ELM1; serine/threonine-protein kinase ELM1 [EC:2.7.11.1]
C YER129W SAK1; serine/threonine protein kinase SAK1 K21157 SAK1; SNF1-activating kinase 1 [EC:2.7.11.1]
C YGL179C TOS3; serine/threonine protein kinase TOS3 K21158 TOS3; serine/threonine-protein kinase TOS3 [EC:2.7.11.1]
C YNL307C MCK1; serine/threonine/tyrosine protein kinase MCK1 K22009 MCK1; protein kinase MCK1
B Bacterial family
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AReceptor serine/threonine kinases (RSTK): TKL group
B TGFBR1 family [OT]
B TGFBR2 family [OT]
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AReceptor tyrosine kinases (RTK)
B EGFR family [OT]
B INSR family [OT]
B PDGFR family [OT]
B FGFR family [OT]
B VEGFR family [OT]
B MET family
B TRK family [OT]
B EPH family [OT]
B AXL family
B ALK family
B TIE family
B ROR family
B DDR family
B RET family
B ROS family
B CCK family
B RYK family
B MUSK family
B LMR family [OT]
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ANon-receptor tyrosine kinases
B ABL family
B ACK family
B CSK family
B FAK family
B FES family
B JAK family [OT]
B SRC family
B TEC family
B SYK family
B Other
B Bacterial
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AHistidine kinases
B OmpR family
B NarL family
B Spo family [OT]
B CitB family [OT]
B LytTR family [OT]
B NtrC family
B CheA family [OT]
B Cell cycle family [OT]
B Lux family [OT]
B LuxR family [OT]
B Other
C YIL147C SLN1; histidine kinase K11231 SLN1; osomolarity two-component system, sensor histidine kinase SLN1 [EC:2.7.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 2, 2024
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Classification taken and modified from Hanks (2003)