+E Transcription factors KO
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Transcription Factors - Saccharomyces cerevisiae (budding yeast)
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AEukaryotic type
B Basic leucine zipper (bZIP)
C AP-1(-like) components, Jun
C AP-1(-like) components, Fos
C AP-1(-like) components, Maf
C AP-1(-like) components, NF-E2
C AP-1(-like) components, Fungal regulators
D YEL009C GCN4; amino acid starvation-responsive transcription factor GCN4 K09464 GCN4; general control protein GCN4
D YML007W YAP1; DNA-binding transcription factor YAP1 K09043 YAP; AP-1-like transcription factor
D YDR423C CAD1; Cad1p K09043 YAP; AP-1-like transcription factor
D YPR199C ARR1; Arr1p K09043 YAP; AP-1-like transcription factor
D YIR018W YAP5; Yap5p K09043 YAP; AP-1-like transcription factor
D YHL009C YAP3; Yap3p K09043 YAP; AP-1-like transcription factor
D YOL028C YAP7; Yap7p K09043 YAP; AP-1-like transcription factor
D YOR028C CIN5; Cin5p K09043 YAP; AP-1-like transcription factor
D YDR259C YAP6; Yap6p K09043 YAP; AP-1-like transcription factor
C AP-1(-like) components, CRE-BP/ATF
D YNL167C SKO1; Sko1p K09051 SKO1; ATF/CREB family transcription factor
C CREB
D YFL031W HAC1; transcription factor HAC1 K16230 HAC1; transcriptional activator HAC1
C C/EBP-like factors
C bZIP/PAR
C Plant bZIP factors
C ZIP only
D YER111C SWI4; SBF complex DNA-binding subunit SWI4 K06649 SWI4; regulatory protein SWI4
D YLR182W SWI6; transcriptional regulator SWI6 K06648 SWI6; regulatory protein SWI6
D YHL020C OPI1; transcriptional regulator OPI1 K21642 OPI1; transcriptional repressor OPI1
D YPL075W GCR1; transcription regulator GCR1 K21646 GCR1; glycolytic genes transcriptional activator GCR1
D YNL199C GCR2; Gcr2p K21671 GCR2; glycolytic genes transcriptional activator GCR2
B Basic helix-loop-helix (bHLH)
C Ubiquitous (class A) factors
C Myogenic transcription factors
C Achaete-Scute
C Tal/Twist/Atonal/Hen, Lymphoid factors
C Tal/Twist/Atonal/Hen, Mesodermal Twist-like factors
D YOR344C TYE7; Tye7p K09074 TYE7; fungal twist-like factor
C Tal/Twist/Atonal/Hen, HEN
C Tal/Twist/Atonal/Hen, Mesp
C Tal/Twist/Atonal/Hen, Atonal
C Tal/Twist/Atonal/Hen, Pancreatic factors
C Hairy, Hairy/E(SPL)
C Hairy, Fungal regulators
D YFR034C PHO4; phosphate-sensing transcription factor PHO4 K06658 PHO4; phosphate system positive regulatory protein PHO4
D YOL001W PHO80; Pho80p K06654 PHO80; phosphate system cyclin PHO80
C Factors with PAS domain
C Yabby
C INO
D YDR123C INO2; Ino2p K09102 INO; heteromeric Ino2p/Ino4p transcription factor
D YOL108C INO4; Ino4p K09102 INO; heteromeric Ino2p/Ino4p transcription factor
C HLH domain only
D YJR060W CBF1; Cbf1p K22484 CBF1; transcriptional regulator CBF1
B Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
C Ubiquitous bHLH-ZIP factors
C Cell cycle controlling factors, Myc
C Cell cycle controlling factors, Mad/Max
C Other bHLH-ZIP factors
B Other basic domains
C NF-1
C RF-X
D YLR176C RFX1; Rfx1p K09173 RFX1_2_3; regulatory factor X 1/2/3
C AP-2 (bHSH)
B Zinc finger
C Cys4 thyroid hormone receptor-like
C Cys4 hepatocyte nuclear factor 4-like
C Cys4 estrogen receptor-like
C Cys4 nerve growth factor IB-like
C Cys4 Fushi tarazu-F1-like
C Cys4 germ cell nuclear factor
C Cys4 Knirps/DAX1-like
C Cys4 GATA-factors
D YFL021W GAT1; Gat1p K09184 GATAF; GATA-binding protein, other eukaryote
D YER040W GLN3; nitrogen-responsive transcriptional regulator GLN3 K09184 GATAF; GATA-binding protein, other eukaryote
D YKR034W DAL80; Dal80p K09184 GATAF; GATA-binding protein, other eukaryote
D YJL110C GZF3; Gzf3p K09184 GATAF; GATA-binding protein, other eukaryote
D YKL185W ASH1; DNA-binding transcription repressor ASH1 K18658 ASH1; transcriptional regulatory protein ASH1
C Cys2His2 SP/KLF family and related proteins
D YDR146C SWI5; DNA-binding transcription factor SWI5 K09202 SWI5; regulatory protein SWI5
C Cys2His2 GLI-like
C Cys2His2 Snail
C Cys2His2 BTB-ZF factors
C Cys2His2 BED
C Cys2His2 PRDM
C Cys2His2 metabolic regulators in fungi
D YLR131C ACE2; DNA-binding transcription factor ACE2 K09238 ACE2; metallothionein expression activator
D YDR216W ADR1; DNA-binding transcription factor ADR1 K09466 ADR1; zinc finger protein ADR1
D YGL035C MIG1; transcription factor MIG1 K09467 MIG; zinc-finger protein CreA/MIG
D YER028C MIG3; Mig3p K09467 MIG; zinc-finger protein CreA/MIG
D YGL209W MIG2; Mig2p K09467 MIG; zinc-finger protein CreA/MIG
D YKL062W MSN4; stress-responsive transcriptional activator MSN4 K09468 MSN2_4; zinc finger protein MSN2/4
D YMR037C MSN2; stress-responsive transcriptional activator MSN2 K09468 MSN2_4; zinc finger protein MSN2/4
D YDR096W GIS1; histone demethylase GIS1 K19798 GIS1; transcriptional activator/repressor GIS1
D YER169W RPH1; Rph1p K19799 RPH1; DNA damage-responsive transcriptional repressor / [histone H3]-trimethyl-L-lysine36 demethylase [EC:1.14.11.69]
C Cys2His2 others
D YPR186C PZF1; Pzf1p K09191 GTF3A; general transcription factor IIIA
D YAR007C RFA1; replication factor A subunit protein RFA1 K07466 RFA1; replication factor A1
D YGR044C RME1; Rme1p K09235 RME1; zinc finger protein RME1
D YLR403W SFP1; zinc-coordinating transcription factor SFP1 K19487 SFP1; transcription factor SFP1
D YNL027W CRZ1; DNA-binding transcription factor CRZ1 K21543 CRZ1; transcription factor CRZ1
D YPL230W USV1; Usv1p K21544 NSF1; C2H2 transcription facotor
D YER130C COM2; Com2p K21545 MNL1; C2H2 transcription facotor
C Cys2HisCys zinc factors
D YOR244W ESA1; NuA4 histone acetyltransferase complex catalytic subunit ESA1 K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
D YCR087C-A uncharacterized protein K15263 LYER; cell growth-regulating nucleolar protein
C Cys3His zinc factors
D YER068W MOT2; CCR4-NOT core ubiquitin-protein ligase subunit MOT2 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
C Cys2CysHis zinc factors
C CXXC CpG-binding proteins
D YPL138C SPP1; Spp1p K14960 CXXC1; COMPASS component SPP1
D YER051W JHD1; [Histone H3]-lysine-36 demethylase K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
C Cys6 metabolic regulators in fungi
D YMR280C CAT8; DNA-binding transcription factor CAT8 K09240 CAT8; transcriptional regulatory protein CAT8
D YBR239C ERT1; Ert1p K27389 RDS2; transcription activator of gluconeogenesis
D YPL133C RDS2; gluconeogenesis transcription factor RDS2 K27389 RDS2; transcription activator of gluconeogenesis
D YJL103C GSM1; Gsm1p K27389 RDS2; transcription activator of gluconeogenesis
D YPL248C GAL4; galactose-responsive transcription factor GAL4 K09241 GAL4; transcriptional regulatory protein GAL4
D YLR451W LEU3; leucine-responsive transcriptional regulator LEU3 K09242 LEU3; transcriptional regulatory protein LEU3
D YDR207C UME6; DNA-binding transcriptional regulator UME6 K09243 UME6; transcriptional regulatory protein UME6
D YDL170W UGA3; Uga3p K09245 UGA3; transcriptional activator protein UGA3
D YML099C ARG81; Arg81p K09246 ARG81; arginine metabolism regulation protein II
D YLR256W HAP1; Hap1p K09247 CYP1; heme activator protein 1
D YKL015W PUT3; Put3p K09248 PUT3; proline utilization trans-activator
D YKL038W RGT1; Rgt1p K21641 RGT1; glucose transport transcription regulator RGT1
C Other zinc fingers
D YNL023C FAP1; Fap1p K12236 NFX1; transcriptional repressor NF-X1
D YNL255C GIS2; mRNA-binding translational activator GIS2 K09250 CNBP; cellular nucleic acid-binding protein
D YKL112W ABF1; DNA-binding protein ABF1 K09249 ABF1; ARS-binding factor 1
B Helix-turn-helix
C Homeo domain ANTP: HOXL
C Homeo domain ANTP: NKL
C Homeo domain Paired-related
C Homeo domain LIM
C Homeo domain POU
C Homeo domain SINE
C Homeo domain ZF
C Homeo domain CUT
D YKL179C COY1; Coy1p K09313 CUTL; homeobox protein cut-like
C Homeo domain PROS
C Homeo domain TALE
D YCL067C HMLALPHA2; homeodomain mating type protein alpha2 K09359 MATA2; mating-type protein A2
D YCR039C MATALPHA2; homeodomain mating type protein alpha2 K09359 MATA2; mating-type protein A2
D YCR096C HMRA2; homeodomain mating type protein A2 K09359 MATA2; mating-type protein A2
C Homeo domain other
D YCR097W HMRA1; Hmra1p K09358 MATA1; mating-type protein A1
D YDL106C PHO2; Pho2p K02646 PHO2; regulatory protein PHO2
D YML027W YOX1; Yox1p K12411 YOX1; homeobox protein YOX1/YHP1
D YDR451C YHP1; Yhp1p K12411 YOX1; homeobox protein YOX1/YHP1
C Fork head/winged helix developmental regulators
C Fork head/winged helix tissue-specific regulators
C Fork head/winged helix cell cycle-controlling factors, E2F
C Fork head/winged helix cell cycle-controlling factors, DP
C Fork head/winged helix other regulators
D YCR065W HCM1; Hcm1p K09413 HCM1; forkhead transcription factor HCM1
D YNL068C FKH2; forkhead family transcription factor FKH2 K24664 FKH; forkhead protein FKH
D YIL131C FKH1; forkhead family transcription factor FKH1 K24664 FKH; forkhead protein FKH
C Heat shock factors
D YGL073W HSF1; stress-responsive transcription factor HSF1 K09419 HSFF; heat shock transcription factor, other eukaryote
D YJR147W HMS2; Hms2p K09419 HSFF; heat shock transcription factor, other eukaryote
C Tryptophan clusters Myb, Myb-factors
C Tryptophan clusters Myb, Myb-like factors
D YKR099W BAS1; Bas1p K09423 BAS1; Myb-like DNA-binding protein BAS1
D YBR049C REB1; DNA-binding protein REB1 K09424 REB1; Myb-like DNA-binding protein REB1
D YDR026C NSI1; Nsi1p K09424 REB1; Myb-like DNA-binding protein REB1
D YNL216W RAP1; DNA-binding transcription factor RAP1 K09426 RAP1; Myb-like DNA-binding protein RAP1
C Tryptophan clusters Ets-type
C Tryptophan clusters interferon-regulating factors
C TEA domain
D YBR083W TEC1; Tec1p K09448 TEAD; transcriptional enhancer factor
C ARID
B beta-Scaffold factors with minor groove contacts
C RHR (Rel homology region) Rel/Ankyrin
C RHR (Rel homology region) Ankyrin only
C RHR (Rel homology region) NF-AT
C STAT
C p53
C MADS-box regulators of differentiation, MEF-2
C MADS-box regulators of differentiation, Homeotic genes
C MADS-box regulators of differentiation, Yeast regulators
D YMR043W MCM1; transcription factor MCM1 K12412 MCM1; pheromone receptor transcription factor
D YMR042W ARG80; Arg80p K19808 ARG80; arginine metabolism regulation protein I
D YPL089C RLM1; Rlm1p K09265 RLM1; transcription factor RLM1
D YBR182C SMP1; Smp1p K19807 SMP1; transcription factor SMP1
C MADS-box responders to external signals
C SAND domain-containing proteins
C TATA-binding proteins
D YER148W SPT15; TATA-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
C HMG SOX
C HMG TCF-1
C HMG2-related
D YML069W POB3; FACT complex subunit POB3 K09272 SSRP1; FACT complex subunit SSRP1/POB3
C UBF
C Other HMG box factors
D YDR174W HMO1; Hmo1p K22483 HMO1; transcriptional regulator HMO1
D YPR065W ROX1; Rox1p K22496 RFG1; repressor RFG1/ROX1
C Heteromeric CCAAT factors
D YGL237C HAP2; transcription activator HAP2 K08064 NFYA; nuclear transcription factor Y, alpha
D YBL021C HAP3; Hap3p K08065 NFYB; nuclear transcription Y subunit beta
D YOR358W HAP5; Hap5p K08066 NFYC; nuclear transcription factor Y, gamma
C Grainyhead
C Cold-shock domain factors, DbpA-like
C Cold-shock domain factors, YB-1/DbpB-like
C Cold-shock domain factors, FRG Y2-like
C Runt
C MYRF
D YHR124W NDT80; transcription factor NDT80 K12769 NDT80; meiosis-specific transcription factor NDT80
B Other transcription factors
C HMGI(Y)
C NUPR
E Line #4
C Pocket domain Rb
C Pocket domain CBP
C T-box
C DMRT
C LRRFIP
C TCP
C AP2/ERF
C WRKY
C LOB
C Copper-fist proteins fungal regulators
D YGL166W CUP2; Cup2p K09281 K09281; copper-fist transcription factor
C Others
D YMR002W MIX17; Mix17p K22758 CHCHD2; coiled-coil-helix-coiled-coil-helix domain-containing protein 2
D YHR084W STE12; homeodomain family transcription factor STE12 K11215 STE12; transcription factor STE12
D YOR083W WHI5; transcriptional repressor WHI5 K12413 WHI5; G1-specific transcriptional repressor WHI5
D YJR094C IME1; transcription factor IME1 K12764 IME1; meiosis-inducing protein 1
D YDR310C SUM1; Sum1p K12779 SUM1; suppressor of MAR1-1 protein
D YMR172W HOT1; Hot1p K19815 HOT1; high-osmolarity-induced transcription protein 1
D YMR164C MSS11; Mss11p K19816 MSS11; transcription activator MSS11
D YEL007W MIT1; Mit1p K21631 GTI1; Gti1/Pac2 family transcription factor
D YHR177W ROF1; Rof1p K21631 GTI1; Gti1/Pac2 family transcription factor
D YMR016C SOK2; Sok2p K12763 EFG1; enhanced filamentous growth protein 1
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AProkaryotic type
B Helix-turn-helix
C AraC family
C LysR family
C DeoR family
C LacI family
C GntR family
C TetR/AcrR family
C Lrp/AsnC family
C LuxR family
C MarR family
C MerR family
C Fur family
C IclR family
C CRP/FNR family
C Rrf2 family
C ArsR family
C XRE family
C PadR family
C Other families
B Ribbon-helix-helix
C CopG family
C Other families
B Other transcription factors
C BglG family
C Others
D YKL070W uncharacterized protein K07734 paiB; transcriptional regulator
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 8, 2024
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Classification taken and modified from TRANSFAC 7.0