+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Streptomyces avermitilis

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APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS E SAVERM_938 aveA1; type I polyketide synthase AVES 1 K14371 aveA1; avermectin polyketide synthase AveA1 E SAVERM_939 aveA2; type I polyketide synthase AVES 2 K24567 aveA2; avermectin polyketide synthase AveA2 E SAVERM_942 aveA3; type I polyketide synthase AVES 3 K24568 aveA3; avermectin polyketide synthase AveA3 E SAVERM_943 aveA4; type I polyketide synthase AVES 4 K24569 aveA4; avermectin polyketide synthase AveA4 D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS D Polyene macrolide PKS D Pimaricinolide synthase D Candicidin PKS D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS C trans-AT PKS D Bacillanene hybrid PKS-NRPS D Chivosazol hybrid PKS-NRPS E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS D Difficidin PKS D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:AN1034.2] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:AN1036.2] C Bacterial type B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS E SAVERM_2838 sppA; putative 3-oxoacyl-ACP synthase I K14667 whiEIII; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-] E SAVERM_2839 sppB; putative chain length factor (3-oxoacyl-ACP synthase II) K14668 whiEIV; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-] E SAVERM_2840 sppC; putative acyl carrier protein K14669 whiEV; minimal PKS acyl carrier protein E SAVERM_2841 sppD; putative cyclase I K14670 whiEVI; aromatase E SAVERM_2842 sppE; putative cyclase II K14671 whiEVII; cyclase C C7-C14 cyclized polyketide type D Octaketide PKS E SAVERM_2376 pks9-4; putative 3-oxoacyl-ACP synthase I K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E SAVERM_2375 pks9-3; putative 3-oxoacyl-ACP synthase II (probably chain length factor) K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E SAVERM_2373 pks9-1; putative acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein E SAVERM_6616 putative polyketide cyclase K05555 actIV; cyclase [EC:4.-.-.-] D Nonaketide PKS E SAVERM_2376 pks9-4; putative 3-oxoacyl-ACP synthase I K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E SAVERM_2375 pks9-3; putative 3-oxoacyl-ACP synthase II (probably chain length factor) K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E SAVERM_2373 pks9-1; putative acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein D Decaketide PKS E SAVERM_2376 pks9-4; putative 3-oxoacyl-ACP synthase I K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E SAVERM_2375 pks9-3; putative 3-oxoacyl-ACP synthase II (probably chain length factor) K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E SAVERM_2373 pks9-1; putative acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein B Type III PKS C Plant type C Fungal type C Bacterial type D SAVERM_7131 rppA; type III polyketide synthase K19580 rppA; 1,3,6,8-tetrahydroxynaphthalene synthase [EC:2.3.1.233] D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:AN2545.2] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase C Iturin family lipopeptide synthetase C Fengycin family lipopeptide synthetase C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D SAVERM_851 putative MbtH-like protein K05375 mbtH; MbtH protein D SAVERM_3644 putative MbtH-like protein K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase C Bacillibactin synthetase C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase C Mycobactin synthetase C Vibriobactin synthetase C Myxochelin synthetase D SAVERM_603 nrps6; putative non-ribosomal peptide synthetase K15653 mxcG; nonribosomal peptide synthetase MxcG C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase # APolyketide tailoring proteins B Hydrolase B Ketoreductase C SAVERM_936 aveF; C-5 ketoreductase K14373 aveF; C-5 ketoreductase C SAVERM_1348 fadC7; putative 3-hydroxyacyl-CoA dehydrogenase K05556 actVI1; ketoreductase RED1 [EC:1.1.1.-] B Oxygenase C SAVERM_941 aveE; cytochrome P450 hydroxylase K14372 aveE; cytochrome P450 hydroxylase [EC:1.14.-.-] C SAVERM_109 cyp1; cytochrome P450 hydroxylase K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C SAVERM_1308 cyp6; cytochrome P450 hydroxylase K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C SAVERM_3882 cyp19; cytochrome P450 hydroxylase K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C SAVERM_3704 cyp17; cytochrome P450 hydroxylase K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C SAVERM_2837 sppH; putative WhiE II homolog K14673 whiEII; putative monooxygenase C SAVERM_2835 sppF; putative polyketide hydroxylase K14672 whiEVIII; putative polyketide hydroxylase B Methylase C SAVERM_937 aveD; C5-O-methyltransferase K14374 aveD; avermectin B 5-O-methyltransferase [EC:2.1.1.-] C SAVERM_2382 putative O-methyltransferase K20421 ncsB1; 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase [EC:2.1.1.303] C SAVERM_2843 putative O-methyltransferase K14251 oxyF; C-methyltransferase [EC:2.1.1.-] B Glycosyltransferase C SAVERM_945 aveBI; dTDP-L-oleandrose transferase (glycosyltransferase) K14375 aveBI; dTDP-L-oleandrosyltransferase [EC:2.4.1.-] B Halogenase B beta-Branched incorporating proteins B Others # ANonribosomal peptide tailoring proteins B Reductase B Thioesterase B Oxygenase B Glycosyltransferase B Aminotransferase B Others ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: February 19, 2024