+F Repair protein KO
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DNA Repair and Recombination Proteins - Sinorhizobium meliloti 1021
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SM_b20708 putative methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E SMc03195 ung; Probable uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SM_b20709 putative 3-methyladenine DNA glycosylase protein K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E SMc00452 mutY; Probable A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SMc02843 nth; Probable endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D SMc02448 mutT; Putative mutator protein 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SMc00461 dnaS; Probable deoxyuridine 5'-triphosphate nucleotidohydrolase dutpase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SM_b20708 putative methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SMc02841 Putative methylated-DNA--protein-cysteine methyltransferase transcription regulator K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D SMc01728 ada; ADA regulatory protein (regulatory protein of adaptative response) K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D SMc02566 alkB; Probable DNA repair system specific for alkylated DNA protein K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E SMc03195 ung; Probable uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SMc02375 Putative DNA polymerase bacteriophage-type K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E SM_b21448 putative DNA polymerase related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E SMc00736 Putative DNA-3-methyladenine glycosidase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E SM_b20709 putative 3-methyladenine DNA glycosylase protein K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E SMc00452 mutY; Probable A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SMc00923 tag; Probable DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E SMc01154 mutM; Probable formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E SMc02843 nth; Probable endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E SM_b20689 xthA4; probable exodeoxyribonuclease III protein K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E SMc02077 xthA2; Putative exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E SMc00956 xthA1; Probable exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E SMc03818 xthA3; Putative exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E SMc00292 recJ; Probable single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E SMc01878 ligA; Probable DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E SMc02850 polA; Probable DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E SMc01235 uvrA; Probable excinuclease ABC subunit A (DNA repair ATP-binding) protein K03701 uvrA; excinuclease ABC subunit A
E SMc04231 uvrB; Probable excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E SMc00602 uvrC; Probable excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E SMc01461 uvrD1; Probable DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SMa2321 uvrD2; UvrD2 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SMc02850 polA; Probable DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E SMc01878 ligA; Probable DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F SMc01317 rpoB; Probable DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F SMc01316 rpoC; Probable DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F SMc01285 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F SMc02408 rpoZ; DNA-directed RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F SMc04450 mfd; Probable transcription-repair coupling factor (TRCF) protein K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E SMc01125 mutS; Probable DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E SMc00932 mutL; Probable DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E SMc00378 xseA; Putative exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E SMc00970 xseB; Putative exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E SMc01375 dnaE1; Probable DNA polymerase III, alpha chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E SMc00415 dnaN; Probable DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SMc00586 Putative DNA polymerase III chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E SMc02802 Putative DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E SMc01190 Putative DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E SMc02789 dnaQ; Probable DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SMa0255 conserved hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SMc02905 dnaX; Putative DNA polymerase III subunit TAU protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E SMc01878 ligA; Probable DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E SMc01461 uvrD1; Probable DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SMa2321 uvrD2; UvrD2 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SMc01233 ssb; Probable single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E SMc03764 vsr; Probable DNA mismatch endonuclease, patch repair protein K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E SMc00760 recA; DNA strand exchange and recombination protein K03553 recA; recombination protein RecA
E SMc03966 ruvA; Probable holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E SMc03965 ruvB; Probable holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SMc03967 ruvC; Probable holliday junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E SMc02496 priA; Probable primosomal protein N' (replication factor Y) K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E SMc00760 recA; DNA strand exchange and recombination protein K03553 recA; recombination protein RecA
E SMc00556 radA; Putative DNA repair protein K04485 radA; DNA repair protein RadA/Sms
E SMc02863 recF; DNA repair protein K03629 recF; DNA replication and repair protein RecF
E SMc00228 recG; Probable ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SMc00292 recJ; Probable single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E SMc02635 recO; Recombinational DNA repair protein (RecF pathway) K03584 recO; DNA repair protein RecO (recombination protein O)
E SMc02908 recR; Probable recombination protein K06187 recR; recombination protein RecR
E SMc01877 recN; Probable DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E SMc03966 ruvA; Probable holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E SMc03965 ruvB; Probable holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SMc03967 ruvC; Probable holliday junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E SMc02760 ATP-dependent nuclease / helicase K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E SMc02759 Hypothetical protein K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E SMc00100 Conserved hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E SM_b21406 conserved hypothetical protein K10979 ku; DNA end-binding protein Ku
E SM_b21407 conserved hypothetical protein K10979 ku; DNA end-binding protein Ku
E SMa0426 conserved hypothetical protein K10979 ku; DNA end-binding protein Ku
E SM_b20686 putative DNA ligase K10979 ku; DNA end-binding protein Ku
E SM_b20912 putative ATP-dependent DNA ligase protein K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E SMa0424 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E SMc03959 Probable ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E SM_b21044 putative ATP-dependent DNA ligase protein K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E SMa0414 conserved hypothetical protein K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F SMc01231 gyrA; Probable DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F SMc02782 gyrB; Probable DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SMc01364 topA; Putative DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F SM_b21445 putative DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F SMc01906 hupB; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F SMc00292 recJ; Probable single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F SMc02635 recO; Recombinational DNA repair protein (RecF pathway) K03584 recO; DNA repair protein RecO (recombination protein O)
F SMc02908 recR; Probable recombination protein K06187 recR; recombination protein RecR
F SMc01878 ligA; Probable DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F SMc01786 himA; Probable integration host factor alpha-subunit K04764 ihfA; integration host factor subunit alpha
F SMc01134 ihfB; Probable integration host factor beta-subunit K05788 ihfB; integration host factor subunit beta
E Supressor
F SMc01566 recQ; Probable ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SMc01235 uvrA; Probable excinuclease ABC subunit A (DNA repair ATP-binding) protein K03701 uvrA; excinuclease ABC subunit A
F SMc04231 uvrB; Probable excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D SMa2355 Nucleotidyltransferase/DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D SMc01373 dinB1; Putative DNA polymerase IV 1 K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D SMc00760 recA; DNA strand exchange and recombination protein K03553 recA; recombination protein RecA
D SMc01183 lexA; Putative LexA repressor transcription regulator K01356 lexA; repressor LexA [EC:3.4.21.88]
D SMc01877 recN; Probable DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D SMa0888 conserved hypothetical protein K14160 imuA; protein ImuA
D SMc03790 Conserved hypothetical protein K14160 imuA; protein ImuA
D SMc03789 imuB; Putative DNA polymerase K14161 imuB; protein ImuB
D SMa0890 conserved hypothetical protein K14161 imuB; protein ImuB
D SMa0892 dnaE3; DnaE3 DNA polymerase III alpha chain K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D SMc03788 dnaE2; Putative DNA polymerase III alpha chain K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D SMc01233 ssb; Probable single-strand binding protein K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D SMc02237 Putative ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D SMc02448 mutT; Putative mutator protein 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SMc00461 dnaS; Probable deoxyuridine 5'-triphosphate nucleotidohydrolase dutpase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SMc01237 nrdJ; Vitamin B12-dependent ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024