+D GENES KO
#
KEGG Orthology (KO) - Streptococcus pyogenes NZ131 (serotype M49)
%
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A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:soz00010]
D Spy49_1181c Glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D Spy49_0188 pgi; Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D Spy49_1018c pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D Spy49_1559c fba; Fructose-bisphosphate aldolase class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D Spy49_0516 tpi; Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D Spy49_0234 plr; NAD-dependent glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D Spy49_1553c pgk; Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D Spy49_1143c gpmA; Phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D Spy49_0563 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Spy49_1017c pyk; Putatove pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D Spy49_0807 acoA; Pyruvate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D Spy49_0808 acoB; Pyruvate dehydrogenase E1 component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D Spy49_0809 acoC; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D Spy49_0810 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Spy49_0904c ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D Spy49_0038 adhE; Alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
D Spy49_0039 adhP; Alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Spy49_0970 pgmA; Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D Spy49_1159c phosphoglucomutase/phosphomannomutase family protein K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D Spy49_1093c gapN; Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) K00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9]
D Spy49_0487 bglA; Putative beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]
D Spy49_1049c Beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]
D Spy49_1235c Beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]
C 00020 Citrate cycle (TCA cycle) [PATH:soz00020]
D Spy49_0810 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Spy49_0807 acoA; Pyruvate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D Spy49_0808 acoB; Pyruvate dehydrogenase E1 component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D Spy49_0809 acoC; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
C 00030 Pentose phosphate pathway [PATH:soz00030]
D Spy49_0188 pgi; Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D Spy49_0224 rpe; Ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D Spy49_1300c tkt; Transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D Spy49_1301c tal; FSA aldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D Spy49_1609c Transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D Spy49_0704 rpiA; Ribose 5-phosphate isomerase A K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D Spy49_1540c deoC; Deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]
D Spy49_0705 deoB; Phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7]
D Spy49_0970 pgmA; Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D Spy49_1159c phosphoglucomutase/phosphomannomutase family protein K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D Spy49_0875c prs; Ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D Spy49_0016 prsA; Ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D Spy49_0533 kdgA; 4-Hydroxy-2-oxoglutarate aldolase / 2-dehydro-3-deoxyphosphogluconate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]
D Spy49_1093c gapN; Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) K00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9]
D Spy49_0532 kdgK; 2-dehydro-3-deoxygluconokinase K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45]
D Spy49_1559c fba; Fructose-bisphosphate aldolase class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D Spy49_1018c pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C 00040 Pentose and glucuronate interconversions [PATH:soz00040]
D Spy49_0459 UDP-glucose dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D Spy49_1806 hasB; putative UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D Spy49_1808 hasC; UDP-glucose pyrophosphorylase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D Spy49_0191c hasC.2; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D Spy49_0156 Hexulose-6-phosphate synthase K03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85]
D Spy49_0157 Hexulose-6-phosphate isomerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22]
D Spy49_0158 araD; L-ribulose-5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]
D Spy49_0224 rpe; Ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
C 00051 Fructose and mannose metabolism [PATH:soz00051]
D Spy49_1413c scrK; Fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D Spy49_1412c pmi; Mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
D Spy49_1018c pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D Spy49_0673 fruK; Tagatose-6-phosphate kinase / 1-phosphofructokinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56]
D Spy49_1559c fba; Fructose-bisphosphate aldolase class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D Spy49_0516 tpi; Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D Spy49_0674 fruA; PTS system, fructose-specific IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202]
D Spy49_0833 PTS system, IIA component, putative K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D Spy49_1354 manL; Putative mannose-specific phosphotransferase system component IIAB K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191]
D Spy49_0835 Putative phosphotransferase system (PTS), enzyme II component C K02795 manY; mannose PTS system EIIC component
D Spy49_1355 manM; PTS system, mannose-specific IIC component K02795 manY; mannose PTS system EIIC component
D Spy49_0836 Putative phospotransferase system (PTS), enzyme II component D K02796 manZ; mannose PTS system EIID component
D Spy49_1356 manN; Putative mannose-specific phosphotransferase system component IID K02796 manZ; mannose PTS system EIID component
C 00052 Galactose metabolism [PATH:soz00052]
D Spy49_1808 hasC; UDP-glucose pyrophosphorylase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D Spy49_0191c hasC.2; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D Spy49_0970 pgmA; Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D Spy49_1159c phosphoglucomutase/phosphomannomutase family protein K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D Spy49_1181c Glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D Spy49_1226c Beta-galactosidase K01190 lacZ; beta-galactosidase [EC:3.2.1.23]
D Spy49_1588c lacC2; Tagatose-6-phosphate kinase (Phosphotagatokinase) K00917 lacC; tagatose 6-phosphate kinase [EC:2.7.1.144]
D Spy49_1018c pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D Spy49_1322c lacD1; Tagatose 1,6-diphosphate aldolase K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40]
D Spy49_1587c lacD2; Tagatose 1,6-diphosphate aldolase K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40]
D Spy49_1326c lacA; Galactose-6-phosphate isomerase lacA subunit K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26]
D Spy49_1325c lacB; Galactose-6-phosphate isomerase lacB subunit K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26]
D Spy49_1589c lacB2; Galactose-6-phosphate isomerase subunit LacB K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26]
D Spy49_1590c lacA2; Galactose-6-phosphate isomerase subunit LacA 2 K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26]
D Spy49_1584c lacG; 6-phospho-beta-galactosidase K01220 E3.2.1.85; 6-phospho-beta-galactosidase [EC:3.2.1.85]
D Spy49_1586c lacF; PTS system, lactose-specific IIA component (EIIA-Lac) (Lactose-permease IIA component) (Phosphotransferase enzyme II, A component) K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207]
D Spy49_1585c lacE; PTS system, lactose-specific IIBC component (EIIBC-Lac) (Lactose-permease IIBC component) (Phosphotransferase enzyme II, BC component) K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207]
D Spy49_1416 scrB; Sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26]
D Spy49_0529c agaF; Putative PTS dependent N-acetyl-galactosamine- and galactosamine IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-]
D Spy49_0527c agaV; PTS system, IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-]
D Spy49_0526c agaW; Putative PTS dependent N-acetyl-galactosamine-IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component
D Spy49_0525c agaD; Putative PTS dependent galactosamine IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component
D Spy49_0551 agaS; Putative tagatose-6-phosphate aldose/ketose isomerase K02082 agaS; D-galactosamine 6-phosphate deaminase/isomerase [EC:3.5.99.-]
C 00053 Ascorbate and aldarate metabolism [PATH:soz00053]
D Spy49_0459 UDP-glucose dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D Spy49_1806 hasB; putative UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D Spy49_1612c Putative transcriptional regulator K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]
D Spy49_0155 PTS system, IIA component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]
D Spy49_1611c PTS system, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D Spy49_0154 PTS system, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D Spy49_1610c sgaT; Transport protein SgaT, putative K03475 ulaA; ascorbate PTS system EIIC component
D Spy49_0153 Transport protein SgaT, putative K03475 ulaA; ascorbate PTS system EIIC component
D Spy49_0160 Conserved hypothetical protein K03476 ulaG; L-ascorbate 6-phosphate lactonase [EC:3.1.1.-]
D Spy49_0156 Hexulose-6-phosphate synthase K03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85]
D Spy49_0157 Hexulose-6-phosphate isomerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22]
D Spy49_0158 araD; L-ribulose-5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]
C 00500 Starch and sucrose metabolism [PATH:soz00500]
D Spy49_1415c scrA; Putative sucrose-specific PTS permease, enzyme II K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211]
D Spy49_1416 scrB; Sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26]
D Spy49_1808 hasC; UDP-glucose pyrophosphorylase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D Spy49_0191c hasC.2; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D Spy49_1700c Putative PTS system, enzyme III K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D Spy49_1045c Putative PTS enzyme III K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D Spy49_1699c PTS system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]
D Spy49_1046c Putative PTS system enzyme II K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]
D Spy49_1043c Putative PTS system IIC component K02761 celB; cellobiose PTS system EIIC component
D Spy49_1698c PTS system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component
D Spy49_0487 bglA; Putative beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]
D Spy49_1049c Beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]
D Spy49_1235c Beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]
D Spy49_1025c glgP; Glycogen phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
D Spy49_1026c malQ; 4-alpha-glucanotransferase K00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25]
D Spy49_1636c PTS system, glucose-specific IIBC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208]
D Spy49_1635c hypothetical protein K06896 mapP; maltose 6'-phosphate phosphatase [EC:3.1.3.90]
D Spy49_1737c Putative PTS system enzyme II K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201]
D Spy49_1736c dexS; Trehalose-6-phosphate hydrolase K01226 treC; trehalose-6-phosphate hydrolase [EC:3.2.1.93]
D Spy49_0970 pgmA; Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D Spy49_1159c phosphoglucomutase/phosphomannomutase family protein K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D Spy49_1181c Glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D Spy49_0188 pgi; Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D Spy49_1413c scrK; Fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:soz00520]
D Spy49_1314c nagA; N-acetylglucosamine-6-phosphate deacetylase K01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]
D Spy49_1115c nagB; Glucosamine-6-phosphate deaminase K02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6]
D Spy49_1413c scrK; Fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D Spy49_1015c glmS; Glucosamine--fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D Spy49_0817 Phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D Spy49_0375 glmU; N-acetylglucosamine-1-phosphate uridyltransferase / Glucosamine-1-phosphate N-acetyltransferase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
D Spy49_0591 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D Spy49_1082c murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D Spy49_0856 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D Spy49_0211 N-acetylmannosamine-6-phosphate 2-epimerase K01788 nanE; N-acylglucosamine-6-phosphate 2-epimerase [EC:5.1.3.9]
D Spy49_0216 nanH; Putative acylneuraminate lyase K01639 E4.1.3.3; N-acetylneuraminate lyase [EC:4.1.3.3]
D Spy49_1181c Glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D Spy49_0970 pgmA; Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D Spy49_1159c phosphoglucomutase/phosphomannomutase family protein K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D Spy49_1808 hasC; UDP-glucose pyrophosphorylase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D Spy49_0191c hasC.2; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D Spy49_0459 UDP-glucose dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D Spy49_1806 hasB; putative UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D Spy49_0833 PTS system, IIA component, putative K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D Spy49_1354 manL; Putative mannose-specific phosphotransferase system component IIAB K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191]
D Spy49_0835 Putative phosphotransferase system (PTS), enzyme II component C K02795 manY; mannose PTS system EIIC component
D Spy49_1355 manM; PTS system, mannose-specific IIC component K02795 manY; mannose PTS system EIIC component
D Spy49_0836 Putative phospotransferase system (PTS), enzyme II component D K02796 manZ; mannose PTS system EIID component
D Spy49_1356 manN; Putative mannose-specific phosphotransferase system component IID K02796 manZ; mannose PTS system EIID component
D Spy49_0188 pgi; Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D Spy49_1412c pmi; Mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
C 00620 Pyruvate metabolism [PATH:soz00620]
D Spy49_0807 acoA; Pyruvate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D Spy49_0808 acoB; Pyruvate dehydrogenase E1 component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D Spy49_0809 acoC; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D Spy49_0810 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Spy49_1442 pfl; Putative pyruvate formate-lyase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54]
D Spy49_0038 adhE; Alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
D Spy49_0039 adhP; Alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Spy49_0098 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D Spy49_0880 pta; Phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D Spy49_1017c pyk; Putatove pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D Spy49_1359c accA; Acetyl-coenzyme A carboxyl transferase alpha chain K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D Spy49_1363c accB; Biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D Spy49_1361c accC; Biotin carboxylase of acetyl-CoA carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D Spy49_1360c accD; Acetyl-coenzyme A carboxyl transferase beta chain K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D Spy49_0292c Putative acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D Spy49_0904c ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D Spy49_0919 D-lactate dehydrogenase K03778 ldhA; D-lactate dehydrogenase [EC:1.1.1.28]
D Spy49_0429c gloA; Lactoylglutathione lyase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]
D Spy49_0539c oxyacylglutathione hydrolase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D Spy49_0864 NAD-dependent malic enzyme K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
D Spy49_0923 Oxaloacetate decarboxylase alpha chain K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]
D Spy49_0939 oadA; Oxaloacetate decarboxylase alpha chain K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]
D Spy49_0926 Oxaloacetate decarboxylase beta chain K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
D Spy49_0933 Oxaloacetate decarboxylase beta chain K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
D Spy49_0924 hypothetical protein K01573 oadG; oxaloacetate decarboxylase (Na+ extruding) subunit gamma
D Spy49_0513 ppc; Phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D Spy49_1268 atoB; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0440 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0123 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:soz00630]
D Spy49_1268 atoB; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0440 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0123 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_1550c glnA; Glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Spy49_0898 Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Spy49_0810 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Spy49_1571c Glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D Spy49_0533 kdgA; 4-Hydroxy-2-oxoglutarate aldolase / 2-dehydro-3-deoxyphosphogluconate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]
C 00640 Propanoate metabolism [PATH:soz00640]
D Spy49_0098 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D Spy49_0880 pta; Phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D Spy49_0810 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Spy49_1442 pfl; Putative pyruvate formate-lyase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54]
D Spy49_1359c accA; Acetyl-coenzyme A carboxyl transferase alpha chain K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D Spy49_1363c accB; Biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D Spy49_1361c accC; Biotin carboxylase of acetyl-CoA carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D Spy49_1360c accD; Acetyl-coenzyme A carboxyl transferase beta chain K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D Spy49_0904c ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D Spy49_1695c gldA; Glycerol dehydrogenase K00005 gldA; glycerol dehydrogenase [EC:1.1.1.6]
C 00650 Butanoate metabolism [PATH:soz00650]
D Spy49_1268 atoB; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0440 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0123 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0124 atoD.2; Acetate CoA-transferase alpha subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
D Spy49_1269 atoD1; Putative acetyl-CoA:acetoacetyl-CoA transferase A subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
D Spy49_1270 atoA; Putative acetyl-CoA:acetoacetyl-CoA transferase b subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]
D Spy49_0125 Butyrate-acetoacetate CoA-transferase, beta subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]
D Spy49_0038 adhE; Alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
D Spy49_0926 Oxaloacetate decarboxylase beta chain K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
D Spy49_0933 Oxaloacetate decarboxylase beta chain K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
D Spy49_0925 Biotin carboxyl carrier protein of oxaloacetate decarboxylase K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
D Spy49_0841 Succinate-semialdehyde dehydrogenase NADP+ K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D Spy49_1442 pfl; Putative pyruvate formate-lyase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54]
D Spy49_0695c mvaS2; Hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D Spy49_1271 Putative oxidoreductase K00019 BDH1; 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30]
D Spy49_0865c Putative zinc-containing alcohol dehydrogenase K18369 adh2; alcohol dehydrogenase [EC:1.1.1.-]
D Spy49_0540 Putative acetoin reductase K03366 butA; meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304]
C 00660 C5-Branched dibasic acid metabolism
C 00562 Inositol phosphate metabolism [PATH:soz00562]
D Spy49_0989c Myo-inositol-1(or 4)-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D Spy49_0373 hypothetical protein K22230 iolU; scyllo-inositol 2-dehydrogenase (NADP+) [EC:1.1.1.-]
D Spy49_0516 tpi; Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:soz00190]
D Spy49_0586 ATP synthase alpha chain K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D Spy49_0588 ATP synthase beta chain K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D Spy49_0587 ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D Spy49_0585 ATP synthase delta chain K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D Spy49_0589 ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D Spy49_0583 ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D Spy49_0584 ATP synthase B chain K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D Spy49_0582 ATP synthase C chain K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D Spy49_0135 ntpA; V-type ATP synthase alpha chain K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
D Spy49_0136 ntpB; V-type sodium ATP synthase subunit B K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B
D Spy49_0133 ntpC; V-type sodium ATP synthase subunit C K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C
D Spy49_0137 ntpD; Putative V-type Na+-ATPase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D
D Spy49_0132 ntpE; Putative V-type Na+-ATPase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E
D Spy49_0134 ntpG; V-type sodium ATP synthase subunit G K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F
D Spy49_0129 hypothetical protein K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H
D Spy49_0130 ntpI; V-type Na+-ATPase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I
D Spy49_0131 ntpK; V-type Na+-ATPase subunit K K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K
D Spy49_0313 Probable manganese-dependent inorganic pyrophosphatase K15986 ppaC; manganese-dependent inorganic pyrophosphatase [EC:3.6.1.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation in photosynthetic organisms
C 00720 Carbon fixation pathways in prokaryotes
C 00680 Methane metabolism [PATH:soz00680]
D Spy49_0898 Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Spy49_0563 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Spy49_0513 ppc; Phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D Spy49_1559c fba; Fructose-bisphosphate aldolase class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D Spy49_1018c pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D Spy49_0098 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D Spy49_0880 pta; Phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D Spy49_1143c gpmA; Phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D Spy49_0453 hypothetical protein K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34]
C 00910 Nitrogen metabolism [PATH:soz00910]
D Spy49_1550c glnA; Glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Spy49_1192c arcC; Carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2]
D Spy49_0201 Carbonic anhydrase-related protein K01673 cynT; carbonic anhydrase [EC:4.2.1.1]
C 00920 Sulfur metabolism [PATH:soz00920]
D Spy49_0554c hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
D Spy49_1606c cysE; Serine acetyltransferase cysE K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D Spy49_1251 cysM; Cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:soz00061]
D Spy49_1359c accA; Acetyl-coenzyme A carboxyl transferase alpha chain K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D Spy49_1363c accB; Biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D Spy49_1361c accC; Biotin carboxylase of acetyl-CoA carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D Spy49_1360c accD; Acetyl-coenzyme A carboxyl transferase beta chain K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D Spy49_1368c acpP2; Acyl carrier protein K02078 acpP; acyl carrier protein
D Spy49_0019 acp; Acyl carrier protein K02078 acpP; acyl carrier protein
D Spy49_1366c fabD; Malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D Spy49_1369c fabH; 3-oxoacyl-(acyl-carrier-protein) synthase, KASIII K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D Spy49_1364c fabF; 3-oxoacyl-(acyl-carrier-protein) synthase, KASII K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D Spy49_0372 Putative dehydrogenease / oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D Spy49_1365c fabG; 3-oxoacyl-(acyl-carrier protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D Spy49_1362c fabz; (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D Spy49_1367c fabK; Enoyl-(acyl-carrier-protein) reductase (FMN) K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
D Spy49_1371c phaB; Trans-2,cis-3-Decenoyl-ACP isomerase K18474 fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14]
D Spy49_0441 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:soz00071]
D Spy49_1268 atoB; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0440 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0123 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0441 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D Spy49_0038 adhE; Alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
D Spy49_0039 adhP; Alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:soz00561]
D Spy49_1571c Glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D Spy49_1695c gldA; Glycerol dehydrogenase K00005 gldA; glycerol dehydrogenase [EC:1.1.1.6]
D Spy49_1307c glpK; Glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30]
D Spy49_0018 Fatty acid/phospholipid synthesis protein plsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D Spy49_0719c hypothetical protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D Spy49_1127c 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D Spy49_0581 Putative transcriptional regulator K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
D Spy49_0434 Putative glucosyl transferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]
D Spy49_0433 Putative sugar transferase K13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208]
D Spy49_0632c Phosphoglycerol transferase K19005 ltaS; lipoteichoic acid synthase [EC:2.7.8.20]
C 00564 Glycerophospholipid metabolism [PATH:soz00564]
D Spy49_0192c gpdA; Glycerol-3-phosphate dehydrogenase NAD(P)+ K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
D Spy49_1306c glpO; Aerobic glycerol-3-phosphate dehydrogenase K00105 E1.1.3.21; alpha-glycerophosphate oxidase [EC:1.1.3.21]
D Spy49_0719c hypothetical protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D Spy49_1127c 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D Spy49_0581 Putative transcriptional regulator K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
D Spy49_0658 Glycerophosphoryl diester phosphodiesterase K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]
D Spy49_1621c cdsA; Phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]
D Spy49_1800c pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
D Spy49_1433c PAP2 family protein K01096 pgpB; phosphatidylglycerophosphatase B [EC:3.1.3.27 3.6.1.75 3.1.3.4 3.6.1.27]
D Spy49_0958c Cardiolipin synthetase K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
D Spy49_1226c Beta-galactosidase K01190 lacZ; beta-galactosidase [EC:3.2.1.23]
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:soz00230]
D Spy49_0376 ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D Spy49_0705 deoB; Phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7]
D Spy49_0970 pgmA; Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D Spy49_1159c phosphoglucomutase/phosphomannomutase family protein K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D Spy49_0875c prs; Ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D Spy49_0016 prsA; Ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D Spy49_0022 purF; Amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D Spy49_0027 purD; Phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D Spy49_0024 purN; Phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D Spy49_0021 purL; Phosphoribosylformylglycinamidine synthase, synthetase subunit/Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
D Spy49_0023 purM; Phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D Spy49_0029 purK; Phosphoribosylaminoimidazole carboxylase ATPase subunit K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
D Spy49_0028 purE; Phosphoribosylaminoimidazole carboxylase catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D Spy49_0020 purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D Spy49_0031 purB; Adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D Spy49_0025 purH; IMP cyclohydrolase/Phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D Spy49_0736 apt; Adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D Spy49_0686c 5-nucleotidase K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
D Spy49_0707 punA; Purine nucleoside phosphorylase K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]
D Spy49_0708 deoD2; Purine nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]
D Spy49_0012 hpt; Hypoxanthine-guanine phosphoribosyltransferase K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
D Spy49_1812c guaB; inosine monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D Spy49_0298 HAM1-like protein K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D Spy49_0887 xpt; Xanthine phosphoribosyltransferase K03816 xpt; xanthine phosphoribosyltransferase [EC:2.4.2.22]
D Spy49_0949 guaA; GMP synthase - glutamine-hydrolyzing K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D Spy49_0885 GMP reductase K00364 guaC; GMP reductase [EC:1.7.1.7]
D Spy49_1265c Guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8]
D Spy49_0341 nrdE.2; Ribonucleotide reductase of class Ib (aerobic), alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Spy49_1097 nrdE1; Ribonucleotide reductase of class Ib (aerobic), alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Spy49_0339 nrdF.2; Ribonucleotide reductase of class Ib (aerobic), beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D Spy49_1099 Ribonucleotide reductase of class Ib (aerobic), beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D Spy49_1747c nrdD; Ribonucleotide reductase of class III (anaerobic), large subunit K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D Spy49_1632c relA; GTP pyrophosphokinase / Guanosine-3,5-bis(Diphosphate) 3-pyrophosphohydrolase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D Spy49_0877 GTP pyrophosphokinase K07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5]
D Spy49_0687 GTP pyrophosphokinase K07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5]
D Spy49_0141 purA; Adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D Spy49_0069 adk; Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D Spy49_1192c arcC; Carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2]
C 00240 Pyrimidine metabolism [PATH:soz00240]
D Spy49_0654 carB; Carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D Spy49_0653 carA; Carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D Spy49_0652 pyrB; Aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D Spy49_0718 pyrC; Dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3]
D Spy49_1144 pyrD; Dihydroorotate dehydrogenase K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1]
D Spy49_0713 pyrE; Orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D Spy49_0712 pyrF; Orotidine 5-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D Spy49_0390 pyrH; Uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D Spy49_1561c pyrG; CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D Spy49_0628 cmk; Cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D Spy49_1090c udk; Uridine kinase K00876 udk; uridine kinase [EC:2.7.1.48]
D Spy49_0686c 5-nucleotidase K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
D Spy49_1542c udp; Uridine phosphorylase K00757 udp; uridine phosphorylase [EC:2.4.2.3]
D Spy49_0322 upp; Uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
D Spy49_0650 pyrR; Uracil phosphoribosyltransferase / Pyrimidine operon regulatory protein pyrR K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]
D Spy49_0975c cdd; Cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5]
D Spy49_1747c nrdD; Ribonucleotide reductase of class III (anaerobic), large subunit K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D Spy49_0341 nrdE.2; Ribonucleotide reductase of class Ib (aerobic), alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Spy49_1097 nrdE1; Ribonucleotide reductase of class Ib (aerobic), alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Spy49_0339 nrdF.2; Ribonucleotide reductase of class Ib (aerobic), beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D Spy49_1099 Ribonucleotide reductase of class Ib (aerobic), beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D Spy49_1421c comEB; Putative late competence protein required for DNA binding K01493 comEB; dCMP deaminase [EC:3.5.4.12]
D Spy49_0326 tmk; Thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D Spy49_0199 dut; Putative deoxyuridine 5-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Spy49_0893 tdk; Thymidine kinase K00857 tdk; thymidine kinase [EC:2.7.1.21]
D Spy49_0696 thyA; Thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
D Spy49_0881 Putative short chain dehydrogenase/reductase K16066 ydfG; 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:soz00250]
D Spy49_1391 asnB; Putative L-asparaginase K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]
D Spy49_1191c asnA; Aspartate--ammonia ligase K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1]
D Spy49_0543 aspC; Aspartate aminotransferase K22457 E2.6.1.14; asparagine---oxo-acid transaminase [EC:2.6.1.14]
D Spy49_1388c Aspartate aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]
D Spy49_0141 purA; Adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D Spy49_0031 purB; Adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D Spy49_0652 pyrB; Aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D Spy49_0841 Succinate-semialdehyde dehydrogenase NADP+ K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D Spy49_1550c glnA; Glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Spy49_0654 carB; Carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D Spy49_0653 carA; Carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D Spy49_1015c glmS; Glucosamine--fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D Spy49_0022 purF; Amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:soz00260]
D Spy49_0898 Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Spy49_1571c Glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D Spy49_1143c gpmA; Phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D Spy49_0881 Putative short chain dehydrogenase/reductase K16066 ydfG; 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-]
D Spy49_0810 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Spy49_1794 sdhB; L-serine dehydratase, beta subunit K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]
D Spy49_1795 sdhA; L-serine dehydratase, alpha subunit K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]
C 00270 Cysteine and methionine metabolism [PATH:soz00270]
D Spy49_1606c cysE; Serine acetyltransferase cysE K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D Spy49_1251 cysM; Cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47]
D Spy49_0151 metB; Cystathionine beta-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D Spy49_0455 Archaeal S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D Spy49_1083c metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D Spy49_0378 pfs; 5-methylthioadenosine nucleosidase / S-adenosylhomocysteine nucleosidase K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9]
D Spy49_1088c hypothetical protein K08968 msrC; L-methionine (R)-S-oxide reductase [EC:1.8.4.14]
D Spy49_1273 luxS; Ribosylhomocysteinase / Autoinducer-2 production protein LuxS K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]
D Spy49_0722 bcaT; Branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Spy49_0904c ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D Spy49_1794 sdhB; L-serine dehydratase, beta subunit K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]
D Spy49_1795 sdhA; L-serine dehydratase, alpha subunit K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]
C 00280 Valine, leucine and isoleucine degradation [PATH:soz00280]
D Spy49_0722 bcaT; Branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Spy49_0810 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Spy49_1268 atoB; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0440 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0123 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0695c mvaS2; Hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:soz00290]
D Spy49_0722 bcaT; Branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Spy49_1388c Aspartate aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]
C 00300 Lysine biosynthesis
D Spy49_1136c murF; UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
C 00310 Lysine degradation [PATH:soz00310]
D Spy49_0810 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Spy49_1268 atoB; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0440 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0123 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0841 Succinate-semialdehyde dehydrogenase NADP+ K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D Spy49_0124 atoD.2; Acetate CoA-transferase alpha subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
D Spy49_1269 atoD1; Putative acetyl-CoA:acetoacetyl-CoA transferase A subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
D Spy49_1270 atoA; Putative acetyl-CoA:acetoacetyl-CoA transferase b subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]
D Spy49_0125 Butyrate-acetoacetate CoA-transferase, beta subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]
C 00220 Arginine biosynthesis [PATH:soz00220]
D Spy49_1195c arcB; Ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D Spy49_1197c arcA; Arginine deiminase K01478 arcA; arginine deiminase [EC:3.5.3.6]
D Spy49_1550c glnA; Glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Spy49_1192c arcC; Carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2]
D Spy49_1388c Aspartate aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]
C 00330 Arginine and proline metabolism [PATH:soz00330]
D Spy49_0714 amiC; Putative amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D Spy49_0100 proC; Pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]
D Spy49_1296c proB; Glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D Spy49_1295c proA; Gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
C 00340 Histidine metabolism [PATH:soz00340]
D Spy49_1730 hutH; Histidine ammonia-lyase K01745 hutH; histidine ammonia-lyase [EC:4.3.1.3]
D Spy49_1724 hutU; Urocanate hydratase K01712 hutU; urocanate hydratase [EC:4.2.1.49]
D Spy49_1723c hutI; Imidazolonepropionase K01468 hutI; imidazolonepropionase [EC:3.5.2.7]
D Spy49_1731 hutG; Formiminoglutamase K01479 hutG; formiminoglutamase [EC:3.5.3.8]
D Spy49_1725 Glutamate formiminotransferase K00603 fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2]
C 00350 Tyrosine metabolism [PATH:soz00350]
D Spy49_0038 adhE; Alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
D Spy49_0039 adhP; Alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Spy49_0841 Succinate-semialdehyde dehydrogenase NADP+ K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00360 Phenylalanine metabolism
D Spy49_0714 amiC; Putative amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
C 00380 Tryptophan metabolism [PATH:soz00380]
D Spy49_0810 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Spy49_1268 atoB; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0440 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0123 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0714 amiC; Putative amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:soz00400]
D Spy49_1220 aroA2; Phospho-2-dehydro-3-deoxyheptonate aldolase K03856 AROA2; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D Spy49_1221 aroB; 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4]
D Spy49_0634 aroD; 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]
D Spy49_0450 aroE.2; Shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
D Spy49_1074c aroK; Shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D Spy49_1075c aroA1; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D Spy49_0635 aroF; Chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D Spy49_1654 trpG; Anthranilate synthase, amidotransferase-like component / Para-aminobenzoate synthase, amidotransferase component K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D Spy49_0556 Chorismate mutase K04516 AROA1; chorismate mutase [EC:5.4.99.5]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism
C 00430 Taurine and hypotaurine metabolism [PATH:soz00430]
D Spy49_0880 pta; Phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D Spy49_0098 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
C 00440 Phosphonate and phosphinate metabolism
C 00450 Selenocompound metabolism [PATH:soz00450]
D Spy49_0151 metB; Cystathionine beta-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D Spy49_0244 Cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D Spy49_1284c nox2; Thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D Spy49_0338 metS; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism [PATH:soz00460]
D Spy49_1391 asnB; Putative L-asparaginase K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]
D Spy49_1191c asnA; Aspartate--ammonia ligase K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1]
D Spy49_0898 Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:soz00470]
D Spy49_1408c alr; Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D Spy49_1137c ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D Spy49_1037c dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
D Spy49_1035c dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
D Spy49_0297 glr; Glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3]
D Spy49_1177c murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
C 00480 Glutathione metabolism [PATH:soz00480]
D Spy49_0981c pepN; Putative lysyl-aminopeptidase K01256 pepN; aminopeptidase N [EC:3.4.11.2]
D Spy49_0727 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D Spy49_0637 gor; Glutathione reductase K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7]
D Spy49_0511c Glutathione peroxidase K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation [PATH:soz00511]
D Spy49_1226c Beta-galactosidase K01190 lacZ; beta-galactosidase [EC:3.2.1.23]
D Spy49_1239 Alpha-mannosidase K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis [PATH:soz00542]
D Spy49_0241 rgpG; Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]
C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:soz00541]
D Spy49_1808 hasC; UDP-glucose pyrophosphorylase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D Spy49_0191c hasC.2; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D Spy49_0459 UDP-glucose dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D Spy49_1806 hasB; putative UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D Spy49_0742 rmlA; Glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Spy49_0745 rmlB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D Spy49_0744 rmlC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D Spy49_0611 rmlD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
D Spy49_1412c pmi; Mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
D Spy49_0375 glmU; N-acetylglucosamine-1-phosphate uridyltransferase / Glucosamine-1-phosphate N-acetyltransferase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
C 00550 Peptidoglycan biosynthesis [PATH:soz00550]
D Spy49_0591 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D Spy49_1082c murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D Spy49_0856 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D Spy49_0287 murC1; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D Spy49_1177c murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D Spy49_1137c ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D Spy49_1136c murF; UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D Spy49_0402 dgk; Diacylglycerol kinase K00887 dgkA; undecaprenol kinase [EC:2.7.1.66]
D Spy49_1658c hypothetical protein K00887 dgkA; undecaprenol kinase [EC:2.7.1.66]
D Spy49_1622c uppS; Undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D Spy49_0239 bacA; Putative undecaprenol kinase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D Spy49_0308 Putative phosphatase K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]
D Spy49_1290c mraY; Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D Spy49_1176c murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D Spy49_1279 pbp1A; Multimodular transpeptidase-transglycosylase K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D Spy49_1706c pbp2A; Multimodular transpeptidase-transglycosylase K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4]
D Spy49_0248c dacA; Penicillin-binding protein 7 precursor (PBP-7) (D-alanyl-D-alanine-endopeptidase) K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D Spy49_0849 dacA1; Penicillin-binding protein 7 precursor (PBP-7) (D-alanyl-D-alanine-endopeptidase) K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D Spy49_1378c D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
D Spy49_0319c murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7]
D Spy49_0814c murC2; Putative UDP-N-acetylmuramyl tripeptide synthetase K23393 murT; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13]
D Spy49_0813c cobQ; Cobyric acid synthase K07009 gatD; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13]
D Spy49_0951c murM2; Putative antimicrobial resistance factor K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10]
D Spy49_0518c murM.1; Putative peptidoglycan branched peptide synthesis protein, serine/alanine adding enzyme K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10]
D Spy49_0517c murN; Putative peptidoglycan branched peptide synthesis protein, alanine adding enzyme K12554 murN; alanine adding enzyme [EC:2.3.2.-]
D Spy49_0086 pbp1b; Multimodular transpeptidase-transglycosylase K03693 pbp1b; penicillin-binding protein 1B
D Spy49_1291c ftsI; Cell division protein ftsI / Peptidoglycan synthetase K12556 pbp2X; penicillin-binding protein 2X
C 00552 Teichoic acid biosynthesis [PATH:soz00552]
D Spy49_0239 bacA; Putative undecaprenol kinase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D Spy49_0308 Putative phosphatase K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]
D Spy49_0241 rgpG; Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]
D Spy49_1037c dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
D Spy49_1035c dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
D Spy49_1036c dltB; Protein dltB K03739 dltB; membrane protein involved in D-alanine export
D Spy49_1034c dltD; Protein dltD precursor K03740 dltD; D-alanine transfer protein
D Spy49_1348c Putative transcription regulator K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-]
D Spy49_1073c psr; Putative PBP 5 synthesis repressor K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-]
D Spy49_0632c Phosphoglycerol transferase K19005 ltaS; lipoteichoic acid synthase [EC:2.7.8.20]
D Spy49_0434 Putative glucosyl transferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis [PATH:soz00543]
D Spy49_0241 rgpG; Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]
D Spy49_1606c cysE; Serine acetyltransferase cysE K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:soz00730]
D Spy49_0640 nifS; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Spy49_0874c Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Spy49_0641 thiI; Probable thiamine biosynthesis protein thiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D Spy49_0223 engC; Probable GTPase engC K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]
D Spy49_0225 Thiamin pyrophosphokinase K00949 thiN; thiamine pyrophosphokinase [EC:2.7.6.2]
D Spy49_0069 adk; Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:soz00740]
D Spy49_1353 hypothetical protein K21064 ycsE; 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.104]
D Spy49_1352 hypothetical protein K21064 ycsE; 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.104]
D Spy49_0992c Riboflavin kinase / FMN adenylyltransferase K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]
D Spy49_0866 Class B acid phosphatase precursor K03788 aphA; acid phosphatase (class B) [EC:3.1.3.2]
D Spy49_0376 ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
C 00750 Vitamin B6 metabolism [PATH:soz00750]
D Spy49_0954c pdxK; Putative pyridoxal kinase K00868 pdxK; pyridoxine kinase [EC:2.7.1.35]
D Spy49_1567c thiD; Phosphomethylpyrimidine kinase K00868 pdxK; pyridoxine kinase [EC:2.7.1.35]
C 00760 Nicotinate and nicotinamide metabolism [PATH:soz00760]
D Spy49_0176 Quinolinate phosphoribosyltransferase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D Spy49_1282c Nicotinate phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D Spy49_0707 punA; Purine nucleoside phosphorylase K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]
D Spy49_0708 deoD2; Purine nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]
D Spy49_0686c 5-nucleotidase K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
D Spy49_0260 Nicotinate-nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]
D Spy49_1281c nadE; NAD synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D Spy49_0144 nga; Nicotine adenine dinucleotide glycohydrolase (NADGH) K18153 nga; NAD+ glycohydrolase [EC:3.2.2.5]
D Spy49_0878 NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D Spy49_0841 Succinate-semialdehyde dehydrogenase NADP+ K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00770 Pantothenate and CoA biosynthesis [PATH:soz00770]
D Spy49_0671 apbA; 2-dehydropantoate 2-reductase K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
D Spy49_0977 coaA; Pantothenate kinase K00867 coaA; type I pantothenate kinase [EC:2.7.1.33]
D Spy49_0967 dpfB; Phosphopantothenoylcysteine synthetase K21977 coaB; phosphopantothenate---cysteine ligase (CTP) [EC:6.3.2.5]
D Spy49_0968 dfp; Phosphopantothenoylcysteine decarboxylase K01598 PPCDC; phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36]
D Spy49_1189c kdtB; Phosphopantetheine adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D Spy49_0417 Dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]
D Spy49_1409c acpS; Holo-(acyl-carrier protein) synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]
D Spy49_0722 bcaT; Branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
C 00780 Biotin metabolism [PATH:soz00780]
D Spy49_1364c fabF; 3-oxoacyl-(acyl-carrier-protein) synthase, KASII K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D Spy49_0372 Putative dehydrogenease / oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D Spy49_1365c fabG; 3-oxoacyl-(acyl-carrier protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D Spy49_1362c fabz; (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D Spy49_1085 birA; Biotin-protein ligase / Biotin operon repressor K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism [PATH:soz00785]
D Spy49_0966c Lipoate-protein ligase A K16869 lipL; octanoyl-[GcvH]:protein N-octanoyltransferase [EC:2.3.1.204]
D Spy49_0812 Lipoate-protein ligase A K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D Spy49_0960c lplA; Lipoate-protein ligase A K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D Spy49_0810 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Spy49_0807 acoA; Pyruvate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D Spy49_0808 acoB; Pyruvate dehydrogenase E1 component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D Spy49_0809 acoC; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
C 00790 Folate biosynthesis [PATH:soz00790]
D Spy49_0852 folE; GTP cyclohydrolase I type 1 K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
D Spy49_0854 folQ; Dihydroneopterin aldolase K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]
D Spy49_0855 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D Spy49_0853 folP; Dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D Spy49_0697 dyr; Dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D Spy49_0851 folC1; Dihydrofolate synthase / Folylpolyglutamate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
D Spy49_0638c folC.2; Dihydrofolate synthase / Folylpolyglutamate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
D Spy49_1653 papB; Para-aminobenzoate synthase, aminase component / Aminodeoxychorismate lyase K03342 pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38]
C 00670 One carbon pool by folate [PATH:soz00670]
D Spy49_0697 dyr; Dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D Spy49_0959c fhs1; Putative formate-tetrahydrofolate ligase K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]
D Spy49_1727 fhs2; Formate--tetrahydrofolate ligase K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]
D Spy49_1158c folD; Putative bifunctional methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D Spy49_1726 Formiminotetrahydrofolate cyclodeaminase K01500 fchA; methenyltetrahydrofolate cyclohydrolase [EC:3.5.4.9]
D Spy49_0898 Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Spy49_0024 purN; Phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D Spy49_0025 purH; IMP cyclohydrolase/Phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D Spy49_1725 Glutamate formiminotransferase K00603 fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2]
D Spy49_1261c fmt; Methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D Spy49_0696 thyA; Thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:soz00900]
D Spy49_1268 atoB; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0440 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0123 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0695c mvaS2; Hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D Spy49_0694c mvaS1; Hydroxymethylglutaryl-CoA reductase K00054 mvaA; hydroxymethylglutaryl-CoA reductase [EC:1.1.1.88]
D Spy49_0690 mvaK1; Mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36]
D Spy49_0692 mvaK2; Phosphomevalonate kinase K00938 E2.7.4.2; phosphomevalonate kinase [EC:2.7.4.2]
D Spy49_0691 mvaD; Diphosphomevalonate decarboxylase K01597 MVD; diphosphomevalonate decarboxylase [EC:4.1.1.33]
D Spy49_0693 Isopentenyl-diphosphate delta-isomerase, FMN-dependent K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D Spy49_1155c fps; Octaprenyl-diphosphate synthase / Dimethylallyltransferase / Geranyltranstransferase / Geranylgeranyl pyrophosphate synthetase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D Spy49_1622c uppS; Undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D Spy49_1300c tkt; Transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis [PATH:soz00523]
D Spy49_0742 rmlA; Glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Spy49_0745 rmlB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D Spy49_0744 rmlC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D Spy49_0611 rmlD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
D Spy49_0745 rmlB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis [PATH:soz00332]
D Spy49_1296c proB; Glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D Spy49_1295c proA; Gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
C 00261 Monobactam biosynthesis
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:soz00521]
D Spy49_1181c Glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D Spy49_0970 pgmA; Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D Spy49_1159c phosphoglucomutase/phosphomannomutase family protein K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D Spy49_0989c Myo-inositol-1(or 4)-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D Spy49_0742 rmlA; Glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Spy49_0745 rmlB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D Spy49_0744 rmlC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D Spy49_0611 rmlD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
D Spy49_1181c Glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
C 00525 Acarbose and validamycin biosynthesis [PATH:soz00525]
D Spy49_0742 rmlA; Glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Spy49_0745 rmlB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
C 00401 Novobiocin biosynthesis
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D Spy49_1654 trpG; Anthranilate synthase, amidotransferase-like component / Para-aminobenzoate synthase, amidotransferase component K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
D Spy49_1366c fabD; Malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D Spy49_0372 Putative dehydrogenease / oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D Spy49_1365c fabG; 3-oxoacyl-(acyl-carrier protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
D Spy49_1368c acpP2; Acyl carrier protein K02078 acpP; acyl carrier protein
D Spy49_0019 acp; Acyl carrier protein K02078 acpP; acyl carrier protein
C 00999 Biosynthesis of various plant secondary metabolites [PATH:soz00999]
D Spy49_0455 Archaeal S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D Spy49_1083c metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D Spy49_0450 aroE.2; Shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation [PATH:soz00362]
D Spy49_1740 Glyoxalase family protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]
D Spy49_0892c Putative 4-oxalocrotonate tautomerase subunit K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
D Spy49_0926 Oxaloacetate decarboxylase beta chain K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
D Spy49_0933 Oxaloacetate decarboxylase beta chain K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
D Spy49_0925 Biotin carboxyl carrier protein of oxaloacetate decarboxylase K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
D Spy49_1268 atoB; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0440 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0123 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00627 Aminobenzoate degradation [PATH:soz00627]
D Spy49_0714 amiC; Putative amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D Spy49_0292c Putative acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D Spy49_0124 atoD.2; Acetate CoA-transferase alpha subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
D Spy49_1269 atoD1; Putative acetyl-CoA:acetoacetyl-CoA transferase A subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
D Spy49_1270 atoA; Putative acetyl-CoA:acetoacetyl-CoA transferase b subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]
D Spy49_0125 Butyrate-acetoacetate CoA-transferase, beta subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation [PATH:soz00625]
D Spy49_0039 adhP; Alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Spy49_0038 adhE; Alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
C 00361 Chlorocyclohexane and chlorobenzene degradation
D Spy49_1740 Glyoxalase family protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]
C 00623 Toluene degradation
C 00622 Xylene degradation [PATH:soz00622]
D Spy49_1740 Glyoxalase family protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]
D Spy49_0892c Putative 4-oxalocrotonate tautomerase subunit K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
C 00633 Nitrotoluene degradation
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation [PATH:soz00643]
D Spy49_0714 amiC; Putative amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D Spy49_1740 Glyoxalase family protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
D Spy49_0892c Putative 4-oxalocrotonate tautomerase subunit K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
C 00626 Naphthalene degradation [PATH:soz00626]
D Spy49_0039 adhP; Alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Spy49_0038 adhE; Alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:soz03020]
D Spy49_0087 rpoB; DNA-directed RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D Spy49_0088 rpoC; DNA-directed RNA polymerase beta subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D Spy49_0074 rpoA; DNA-directed RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D Spy49_1263c DNA-directed RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D Spy49_1562c rpoE; DNA-directed RNA polymerase delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
C 03022 Basal transcription factors
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:soz03010]
D Spy49_0724 rpsA; SSU ribosomal protein S1p K02945 RP-S1; small subunit ribosomal protein S1
D Spy49_1733 rpsB; SSU ribosomal protein S2p (SAe) K02967 RP-S2; small subunit ribosomal protein S2
D Spy49_0053 rpsC; SSU ribosomal protein S3p (S3e) K02982 RP-S3; small subunit ribosomal protein S3
D Spy49_1786c rpsD; SSU ribosomal protein S4p (S9e) K02986 RP-S4; small subunit ribosomal protein S4
D Spy49_0065 rpsE; SSU ribosomal protein S5p (S2e) K02988 RP-S5; small subunit ribosomal protein S5
D Spy49_1428c rpsF; SSU ribosomal protein S6p K02990 RP-S6; small subunit ribosomal protein S6
D Spy49_0231 rpsG; SSU ribosomal protein S7p (S5e) K02992 RP-S7; small subunit ribosomal protein S7
D Spy49_0061 rpsH; SSU ribosomal protein S8p (S15Ae) K02994 RP-S8; small subunit ribosomal protein S8
D Spy49_1595c rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D Spy49_0044 rpsJ; SSU ribosomal protein S10p (S20e) K02946 RP-S10; small subunit ribosomal protein S10
D Spy49_0073 rpsK; SSU ribosomal protein S11p (S14e) K02948 RP-S11; small subunit ribosomal protein S11
D Spy49_0230 rpsL; SSU ribosomal protein S12p (S23e) K02950 RP-S12; small subunit ribosomal protein S12
D Spy49_0072 rpsM; SSU ribosomal protein S13p (S18e) K02952 RP-S13; small subunit ribosomal protein S13
D Spy49_1544 rpsN2; SSU ribosomal protein S14p (S29e) K02954 RP-S14; small subunit ribosomal protein S14
D Spy49_0060 rpsN.1; SSU ribosomal protein S14p (S29e) K02954 RP-S14; small subunit ribosomal protein S14
D Spy49_1613c rpsO; SSU ribosomal protein S15p (S13e) K02956 RP-S15; small subunit ribosomal protein S15
D Spy49_0659 rpsP; SSU ribosomal protein S16p K02959 RP-S16; small subunit ribosomal protein S16
D Spy49_0056 rpsQ; SSU ribosomal protein S17p (S11e) K02961 RP-S17; small subunit ribosomal protein S17
D Spy49_1426c rpsR; SSU ribosomal protein S18p K02963 RP-S18; small subunit ribosomal protein S18
D Spy49_0050 rpsS; SSU ribosomal protein S19p (S15e) K02965 RP-S19; small subunit ribosomal protein S19
D Spy49_0978 prsT; SSU ribosomal protein S20p K02968 RP-S20; small subunit ribosomal protein S20
D Spy49_0606 rpsU; SSU ribosomal protein S21p K02970 RP-S21; small subunit ribosomal protein S21
D Spy49_0388 rplA; LSU ribosomal protein L1p (L10Ae) K02863 RP-L1; large subunit ribosomal protein L1
D Spy49_0049 rplB; LSU ribosomal protein L2p (L8e) K02886 RP-L2; large subunit ribosomal protein L2
D Spy49_0045 rplC; LSU ribosomal protein L3p (L3e) K02906 RP-L3; large subunit ribosomal protein L3
D Spy49_0046 rplD; LSU ribosomal protein L4p (L1e) K02926 RP-L4; large subunit ribosomal protein L4
D Spy49_0059 rplE; LSU ribosomal protein L5p (L11e) K02931 RP-L5; large subunit ribosomal protein L5
D Spy49_0062 rplF; LSU ribosomal protein L6p (L9e) K02933 RP-L6; large subunit ribosomal protein L6
D Spy49_0848 rplL; LSU ribosomal protein L7/L12 (L23e) K02935 RP-L7; large subunit ribosomal protein L7/L12
D Spy49_1789c rplI; LSU ribosomal protein L9p K02939 RP-L9; large subunit ribosomal protein L9
D Spy49_0846 rplJ; LSU ribosomal protein L10p (P0) K02864 RP-L10; large subunit ribosomal protein L10
D Spy49_0387 rplK; LSU ribosomal protein L11p (L12e) K02867 RP-L11; large subunit ribosomal protein L11
D Spy49_1596c rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D Spy49_0057 rplN; LSU ribosomal protein L14p (L23e) K02874 RP-L14; large subunit ribosomal protein L14
D Spy49_0067 rplO; LSU ribosomal protein L15p (L27Ae) K02876 RP-L15; large subunit ribosomal protein L15
D Spy49_0054 rplP; LSU ribosomal protein L16p (L10e) K02878 RP-L16; large subunit ribosomal protein L16
D Spy49_0075 rplQ; LSU ribosomal protein L17p K02879 RP-L17; large subunit ribosomal protein L17
D Spy49_0064 rplR; LSU ribosomal protein L18p (L5e) K02881 RP-L18; large subunit ribosomal protein L18
D Spy49_0558 rplS; LSU ribosomal protein L19p K02884 RP-L19; large subunit ribosomal protein L19
D Spy49_0631 rplT; LSU ribosomal protein L20p K02887 RP-L20; large subunit ribosomal protein L20
D Spy49_0643 rplU; LSU ribosomal protein L21p K02888 RP-L21; large subunit ribosomal protein L21
D Spy49_0052 rplV; LSU ribosomal protein L22p (L17e) K02890 RP-L22; large subunit ribosomal protein L22
D Spy49_0048 rplW; LSU ribosomal protein L23p (L23Ae) K02892 RP-L23; large subunit ribosomal protein L23
D Spy49_0058 rplX; LSU ribosomal protein L24p (L26e) K02895 RP-L24; large subunit ribosomal protein L24
D Spy49_0645 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D Spy49_1558c rpmB; LSU ribosomal protein L28p K02902 RP-L28; large subunit ribosomal protein L28
D Spy49_0055 rpmC; LSU ribosomal protein L29p (L35e) K02904 RP-L29; large subunit ribosomal protein L29
D Spy49_0066 rpmD; LSU ribosomal protein L30p (L7e) K02907 RP-L30; large subunit ribosomal protein L30
D Spy49_0552c rpmE; LSU ribosomal protein L31p K02909 RP-L31; large subunit ribosomal protein L31
D Spy49_1770 rpmF; LSU ribosomal protein L32p K02911 RP-L32; large subunit ribosomal protein L32
D Spy49_0420 LSU ribosomal protein L33p K02913 RP-L33; large subunit ribosomal protein L33
D Spy49_1705c rpmG1; LSU ribosomal protein L33p K02913 RP-L33; large subunit ribosomal protein L33
D Spy49_1771 rpmG2; LSU ribosomal protein L33p K02913 RP-L33; large subunit ribosomal protein L33
D Spy49_0210 rpmH; LSU ribosomal protein L34p K02914 RP-L34; large subunit ribosomal protein L34
D Spy49_0630 rpmI; LSU ribosomal protein L35p K02916 RP-L35; large subunit ribosomal protein L35
D Spy49_0071 rpmJ; LSU ribosomal protein L36p K02919 RP-L36; large subunit ribosomal protein L36
D Spy49_rRNA16s5 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA16s6 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA16s4 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA16s2 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA16s1 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA16s3 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA23s2 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA23s4 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA23s1 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA23s5 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA23s6 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA23s3 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA5s1 5S Subunit Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_rRNA5s3 5S Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_rRNA5s2 5S Subunit Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_rRNA5s5 5S Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_rRNA5s4 5S Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_rRNA5s6 5S Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:soz00970]
D Spy49_tRNAala1 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Spy49_tRNAala2 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Spy49_tRNAala3 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Spy49_tRNAala5 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Spy49_tRNAala6 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Spy49_tRNAala4 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Spy49_tRNAarg5 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Spy49_tRNAarg7 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Spy49_tRNAarg4 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Spy49_tRNAarg1 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Spy49_tRNAarg2 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Spy49_tRNAarg3 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Spy49_tRNAarg6 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Spy49_tRNAasn3 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D Spy49_tRNAasn1 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D Spy49_tRNAasn2 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D Spy49_tRNAasp1 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D Spy49_tRNAasp3 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D Spy49_tRNAasp2 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D Spy49_tRNAcys1 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D Spy49_tRNAgln1 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D Spy49_tRNAgln2 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D Spy49_tRNAglu3 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D Spy49_tRNAglu1 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D Spy49_tRNAglu2 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D Spy49_tRNAgly3 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Spy49_tRNAgly4 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Spy49_tRNAgly1 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Spy49_tRNAgly2 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Spy49_tRNAhis1 tRNA-His K14226 tRNA-His; tRNA His
D Spy49_tRNAile1 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D Spy49_tRNAile3 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D Spy49_tRNAile2 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D Spy49_tRNAleu2 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Spy49_tRNAleu4 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Spy49_tRNAleu5 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Spy49_tRNAleu7 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Spy49_tRNAleu1 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Spy49_tRNAleu3 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Spy49_tRNAleu6 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Spy49_tRNAlys1 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Spy49_tRNAlys2 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Spy49_tRNAlys3 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Spy49_tRNAmet1 tRNA-Met K14230 tRNA-Met; tRNA Met
D Spy49_tRNAmet3 tRNA-Met K14230 tRNA-Met; tRNA Met
D Spy49_tRNAmet4 tRNA-Met K14230 tRNA-Met; tRNA Met
D Spy49_tRNAmet2 tRNA-Met K14230 tRNA-Met; tRNA Met
D Spy49_tRNAphe1 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D Spy49_tRNAphe2 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D Spy49_tRNApro1 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Spy49_tRNApro2 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Spy49_tRNApseudo1 pseudogene K14233 tRNA-Ser; tRNA Ser
D Spy49_tRNApseudo3 pseudogene K14233 tRNA-Ser; tRNA Ser
D Spy49_tRNAser1 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Spy49_tRNApseudo2 pseudogene K14233 tRNA-Ser; tRNA Ser
D Spy49_tRNAthr3 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Spy49_tRNAthr1 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Spy49_tRNAthr2 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Spy49_tRNAthr4 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Spy49_tRNAtrp1 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D Spy49_tRNAtyr1 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D Spy49_tRNAtyr2 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D Spy49_tRNAval4 tRNA-Val K14237 tRNA-Val; tRNA Val
D Spy49_tRNAval3 tRNA-Val K14237 tRNA-Val; tRNA Val
D Spy49_tRNAval2 tRNA-Val K14237 tRNA-Val; tRNA Val
D Spy49_tRNAval1 tRNA-Val K14237 tRNA-Val; tRNA Val
D Spy49_0203 gluS; Glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
D Spy49_1383c gatA; Aspartyl-tRNA(Asn) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D Spy49_1382c gatB; Aspartyl-tRNA(Asn) amidotransferase subunit B Glutamyl-tRNA(Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D Spy49_1384c gatC; Aspartyl-tRNA(Asn) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D Spy49_1108c alaS; Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Spy49_1768c aspS; Aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D Spy49_0473 Asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D Spy49_0544 asnS; Asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D Spy49_1311c glyQ; Glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D Spy49_1310c glyS; Glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D Spy49_0435 thrS; Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Spy49_1358 serS; Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Spy49_1604c cysS; Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Spy49_0338 metS; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Spy49_1261c fmt; Methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D Spy49_1215c valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Spy49_0152 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Spy49_1167c ileS; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Spy49_0503c lysS; Lysyl-tRNA synthetase (class II) K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D Spy49_1762 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Spy49_1619c proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Spy49_1769c hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Spy49_0476 hypothetical protein K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Spy49_0596 pheS; Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Spy49_0597 pheT; Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Spy49_0084 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Spy49_1813c trsA; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:soz03060]
D Spy49_0068 secY; Preprotein translocase secY subunit K03076 secY; preprotein translocase subunit SecY
D Spy49_1704c Preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D Spy49_0421 Preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D Spy49_1624c Preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D Spy49_0208 Membrane protein oxaA 1 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
D Spy49_0291 oxaA; Membrane protein oxaA 2 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
D Spy49_1410c secA; Protein export cytoplasm protein SecA ATPase RNA helicase K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D Spy49_0945c ffh; Signal recognition particle, subunit Ffh SRP54 K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D Spy49_0482 ftsY; Signal recognition particle receptor protein FtsY alpha subunit K03110 ftsY; fused signal recognition particle receptor
D Spy49_1438 spi; Putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D Spy49_1016c sipC; Putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D Spy49_0113 lepA-1; Putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D Spy49_0647 lsp; Putative prolipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:soz04122]
D Spy49_0640 nifS; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Spy49_0874c Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Spy49_1793c trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D Spy49_0641 thiI; Probable thiamine biosynthesis protein thiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
C 03050 Proteasome
C 03018 RNA degradation [PATH:soz03018]
D Spy49_0563 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Spy49_1608c pnp; Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D Spy49_0422 vacB; Putative exoribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D Spy49_1132c deaD1; Putative ATP-dependent RNA helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D Spy49_1266c hypothetical protein K18682 rny; ribonucrease Y [EC:3.1.-.-]
D Spy49_1549 hypothetical protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D Spy49_0801 hypothetical protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D Spy49_1018c pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D Spy49_1374c dnaK; Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK
D Spy49_1715c groEL; Heat shock protein 60 family chaperone GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:soz03030]
D Spy49_1534c dnaQ; Putative DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D Spy49_1019c dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D Spy49_1618c polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
D Spy49_1087c dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D Spy49_0327 DNA polymerase III delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D Spy49_1123c holA; DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D Spy49_0002 dnaN; Beta subunit of DNA polymerase III K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D Spy49_1788c dnaC; Replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D Spy49_0608 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D Spy49_1427c ssb2; Single-strand binding protein 2 K03111 ssb; single-strand DNA-binding protein
D Spy49_1500c Single-strand binding protein 3 K03111 ssb; single-strand DNA-binding protein
D Spy49_0107 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D Spy49_0913 rnh; Ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Spy49_1437 Ribonuclease HIII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4]
D Spy49_0163 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D Spy49_0580 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03410 Base excision repair [PATH:soz03410]
D Spy49_0738 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D Spy49_0717 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
D Spy49_1430 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D Spy49_0416 fpg; Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D Spy49_1755c tag; DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
D Spy49_0334c exoA; Putative 3-exo-deoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D Spy49_0163 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D Spy49_0735 recJ; Single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Spy49_0580 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03420 Nucleotide excision repair [PATH:soz03420]
D Spy49_0006 trcF; Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D Spy49_1423c uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
D Spy49_1039c uvrB; Excinuclease ABC (Subunit B), helicase subunit of the DNA excision repair complex K03702 uvrB; excinuclease ABC subunit B
D Spy49_0842 uvrC; Putative excinuclease ABC K03703 uvrC; excinuclease ABC subunit C
D Spy49_1007c pcrA; Putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D Spy49_0163 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D Spy49_0580 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03430 Mismatch repair [PATH:soz03430]
D Spy49_1759c mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Spy49_1434c mutS2; Putative DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2
D Spy49_1758c mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Spy49_1007c pcrA; Putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D Spy49_1157c xseA; Probable exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D Spy49_1156c xseB; Probable exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D Spy49_0735 recJ; Single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Spy49_1427c ssb2; Single-strand binding protein 2 K03111 ssb; single-strand DNA-binding protein
D Spy49_1500c Single-strand binding protein 3 K03111 ssb; single-strand DNA-binding protein
D Spy49_0107 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D Spy49_1019c dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D Spy49_1618c polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
D Spy49_0002 dnaN; Beta subunit of DNA polymerase III K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D Spy49_1087c dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D Spy49_1123c holA; DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D Spy49_0327 DNA polymerase III delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D Spy49_1534c dnaQ; Putative DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D Spy49_0580 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03440 Homologous recombination [PATH:soz03440]
D Spy49_0735 recJ; Single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Spy49_1427c ssb2; Single-strand binding protein 2 K03111 ssb; single-strand DNA-binding protein
D Spy49_1500c Single-strand binding protein 3 K03111 ssb; single-strand DNA-binding protein
D Spy49_0107 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D Spy49_1810 recF; Recombination protein F K03629 recF; DNA replication and repair protein RecF
D Spy49_0017 recO; DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O)
D Spy49_1138c recR; Recombination protein recR K06187 recR; recombination protein RecR
D Spy49_1753c recA; RecA protein K03553 recA; recombination protein RecA
D Spy49_0163 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D Spy49_1756c ruvA; Holliday junction DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
D Spy49_0033 ruvB; Holliday junction DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D Spy49_1394c recG; Putative ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D Spy49_1439 recD; Exodeoxyribonuclease V alpha chain K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
D Spy49_1019c dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D Spy49_1618c polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
D Spy49_0002 dnaN; Beta subunit of DNA polymerase III K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D Spy49_1087c dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D Spy49_1123c holA; DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D Spy49_0327 DNA polymerase III delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D Spy49_1534c dnaQ; Putative DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D Spy49_1262c priA; Arrested fork binding K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
C 03450 Non-homologous end-joining
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1 [PATH:soz03250]
D Spy49_0384c cypB; Putative cyclophilin-type protein K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus and Lyssavirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:soz02010]
D Spy49_0840 Iron ABC transporter, iron-binding protein K02012 afuA; iron(III) transport system substrate-binding protein
D Spy49_0860 potD; ABC transporter, periplasmic spermidine putrescine-binding protein potD K11069 potD; spermidine/putrescine transport system substrate-binding protein
D Spy49_0859 potC; Spermidine Putrescine ABC transporter permease component potC K11070 potC; spermidine/putrescine transport system permease protein
D Spy49_0858 potB; Spermidine Putrescine ABC transporter permease component potB K11071 potB; spermidine/putrescine transport system permease protein
D Spy49_0857 potA; Spermidine Putrescine transport ATP-binding protein potA K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11]
D Spy49_0162 opuABC; L-proline Glycine Betaine ABC transport system permease protein proW K02001 proW; glycine betaine/proline transport system permease protein
D Spy49_0161 opuAA; L-proline Glycine Betaine ABC transport ATP-binding protein proV K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9]
D Spy49_0884 proX; L-proline glycine betaine binding ABC transporter protein proX / Osmotic adaptation K05845 opuC; osmoprotectant transport system substrate-binding protein
D Spy49_0883 proV; L-proline Glycine Betaine ABC transport ATP-binding protein proV K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]
D Spy49_1628c msmK; Sugar ABC transporter, ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D Spy49_1028 malE; Maltose maltodextrin ABC transporter, substrate binding periplasmic protein malE K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein
D Spy49_1029 malF; Maltose transport system permease protein malF K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D Spy49_1030 malG; Maltose transport system permease protein malG K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D Spy49_1230c ABC transporter, substrate-binding protein K17318 lplA; putative aldouronate transport system substrate-binding protein
D Spy49_1233c Putative sugar-binding transport protein K17319 lplB; putative aldouronate transport system permease protein
D Spy49_1231c ABC transporter, permease protein K17320 lplC; putative aldouronate transport system permease protein
D Spy49_0974c Putative lipoprotein K07335 bmpA; basic membrane protein A and related proteins
D Spy49_0142 Putative ABC transporter K07335 bmpA; basic membrane protein A and related proteins
D Spy49_0972c Putative sugar ABC transporter K23535 nupB; general nucleoside transport system permease protein
D Spy49_0971c Putative sugar ABC transporter K23536 nupC; general nucleoside transport system permease protein
D Spy49_0973c Putative sugar ABC transporter K23537 nupA; general nucleoside transport system ATP-binding protein
D Spy49_0987c pstS; Phosphate ABC transporter, periplasmic phosphate-binding protein pstS K02040 pstS; phosphate transport system substrate-binding protein
D Spy49_0986 pstC; Phosphate transport system permease protein pstC K02037 pstC; phosphate transport system permease protein
D Spy49_0985c pstA; Phosphate transport system permease protein pstA K02038 pstA; phosphate transport system permease protein
D Spy49_0983c pstB; Phosphate transport ATP-binding protein pstB K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D Spy49_0984c pstB2; Phosphate transport ATP-binding protein pstB2 K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D Spy49_1040 glnP; Glutamine ABC transporter, glutamine-binding protein/permease protein K10036 glnH; glutamine transport system substrate-binding protein
D Spy49_1041 glnQ; Glutamine transport ATP-binding protein glnQ K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1]
D Spy49_0715 Putative ABC transporter K02424 tcyA; L-cystine transport system substrate-binding protein
D Spy49_0266 atmA; ABC transporter, substrate-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein
D Spy49_0716 Probable amino-acid ABC transporter permease protein yckA K10009 tcyB; L-cystine transport system permease protein
D Spy49_1287c Putative amino acid ABC transproter K10009 tcyB; L-cystine transport system permease protein
D Spy49_1286c Amino acid ABC transporter, ATP-binding protein K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1]
D Spy49_0605 Putative ABC transporter K23059 artP; arginine/lysine/histidine transporter system substrate-binding protein
D Spy49_1162c Putative amino acid ABC transporter K17077 artQ; arginine/lysine/histidine transport system permease protein
D Spy49_1161c gtr; Putative amino acid ABC transporter K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1]
D Spy49_0237c Putative glutamine-binding periplasmic protein K17073 lysX1; putative lysine transport system substrate-binding protein
D Spy49_0236c Amino acid ABC transporter, ATP-binding protein K17076 lysY; putative lysine transport system ATP-binding protein
D Spy49_0268 atmB; Methionine ABC transporter substrate-binding protein K02073 metQ; D-methionine transport system substrate-binding protein
D Spy49_0270 atmE; Methionine ABC transporter permease protein K02072 metI; D-methionine transport system permease protein
D Spy49_0269 atmD; Putative ABC transporter K02071 metN; D-methionine transport system ATP-binding protein
D Spy49_0249 oppA; Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein oppA K15580 oppA; oligopeptide transport system substrate-binding protein
D Spy49_0250 oppB; Oligopeptide transport system permease protein K15581 oppB; oligopeptide transport system permease protein
D Spy49_0251 oppC; Oligopeptide transport system permease protein oppC K15582 oppC; oligopeptide transport system permease protein
D Spy49_0252 oppD; Oligopeptide transport ATP-binding protein oppD K15583 oppD; oligopeptide transport system ATP-binding protein
D Spy49_0253 oppF; Oligopeptide transport ATP-binding protein oppF K10823 oppF; oligopeptide transport system ATP-binding protein
D Spy49_1667c lmb; Laminin-binding surface protein K09815 znuA; zinc transport system substrate-binding protein
D Spy49_0549 adcA; Zinc-binding protein adcA precursor K09815 znuA; zinc transport system substrate-binding protein
D Spy49_0082 adrB; Putative ABC transporter K09816 znuB; zinc transport system permease protein
D Spy49_0081 adrC; ABC transporter K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D Spy49_0381 mtsA; Metal ABC transporter substrate-binding lipoprotein precursor K11704 mtsA; iron/zinc/manganese/copper transport system substrate-binding protein
D Spy49_0383 mtsC; Integral membrane protein MtsC, ABC transporter K11705 mtsC; iron/zinc/manganese/copper transport system permease protein
D Spy49_0382 mtsB; ATP-binding protein MtsB K11706 mtsB; iron/zinc/manganese/copper transport system ATP-binding protein
D Spy49_0183 bioY; Biotin transporter bioY K03523 bioY; biotin transport system substrate-specific component
D Spy49_1797c ABC-type cobalt transport system, permease component CbiQ K16785 ecfT; energy-coupling factor transport system permease protein
D Spy49_1396c ABC-type cobalt transport system, permease component CbiQ K16785 ecfT; energy-coupling factor transport system permease protein
D Spy49_1799c hypothetical protein K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D Spy49_1798c ABC-type cobalt transport system, ATPase component CbiO K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D Spy49_0538 ftsX; Cell division protein ftsX K09811 ftsX; cell division transport system permease protein
D Spy49_0537 ftsE; Cell division transporter, ATP-binding protein ftsE K09812 ftsE; cell division transport system ATP-binding protein
D Spy49_0194 Putative ABC transporter, ATP-binding protein K18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump
D Spy49_0195 ABC transporter, ATP-binding/permease protein K18892 patB; ATP-binding cassette, subfamily B, multidrug efflux pump
D Spy49_0901 ABC transporter, ATP-binding/permease protein K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump
D Spy49_0902 Putative ABC transporter K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump
C 02060 Phosphotransferase system (PTS) [PATH:soz02060]
D Spy49_1094c ptsI; Phosphoenolpyruvate-protein phosphotransferase of PTS system K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
D Spy49_1095c ptsH; Phosphocarrier protein of PTS system K02784 ptsH; phosphocarrier protein HPr
D Spy49_1636c PTS system, glucose-specific IIBC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208]
D Spy49_1415c scrA; Putative sucrose-specific PTS permease, enzyme II K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211]
D Spy49_0485 Beta-glucoside permease IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-]
D Spy49_1737c Putative PTS system enzyme II K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201]
D Spy49_1586c lacF; PTS system, lactose-specific IIA component (EIIA-Lac) (Lactose-permease IIA component) (Phosphotransferase enzyme II, A component) K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207]
D Spy49_1585c lacE; PTS system, lactose-specific IIBC component (EIIBC-Lac) (Lactose-permease IIBC component) (Phosphotransferase enzyme II, BC component) K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207]
D Spy49_1700c Putative PTS system, enzyme III K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D Spy49_1045c Putative PTS enzyme III K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D Spy49_1699c PTS system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]
D Spy49_1046c Putative PTS system enzyme II K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]
D Spy49_1043c Putative PTS system IIC component K02761 celB; cellobiose PTS system EIIC component
D Spy49_1698c PTS system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component
D Spy49_0833 PTS system, IIA component, putative K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D Spy49_1354 manL; Putative mannose-specific phosphotransferase system component IIAB K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191]
D Spy49_0835 Putative phosphotransferase system (PTS), enzyme II component C K02795 manY; mannose PTS system EIIC component
D Spy49_1355 manM; PTS system, mannose-specific IIC component K02795 manY; mannose PTS system EIIC component
D Spy49_0836 Putative phospotransferase system (PTS), enzyme II component D K02796 manZ; mannose PTS system EIID component
D Spy49_1356 manN; Putative mannose-specific phosphotransferase system component IID K02796 manZ; mannose PTS system EIID component
D Spy49_0834 PTS system, IIB component K19507 gfrB; fructoselysine/glucoselysine PTS system EIIB component [EC:2.7.1.-]
D Spy49_0529c agaF; Putative PTS dependent N-acetyl-galactosamine- and galactosamine IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-]
D Spy49_0527c agaV; PTS system, IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-]
D Spy49_0526c agaW; Putative PTS dependent N-acetyl-galactosamine-IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component
D Spy49_0525c agaD; Putative PTS dependent galactosamine IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component
D Spy49_1329c Putative PTS system, enzyme IIA component K20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204]
D Spy49_1328c PTS system, IIB component, putative K20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204]
D Spy49_1327c Putative PTS system, enzyme IIC component K20114 gatC; galactose PTS system EIIC component
D Spy49_1612c Putative transcriptional regulator K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]
D Spy49_0155 PTS system, IIA component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]
D Spy49_1611c PTS system, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D Spy49_0154 PTS system, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D Spy49_1610c sgaT; Transport protein SgaT, putative K03475 ulaA; ascorbate PTS system EIIC component
D Spy49_0153 Transport protein SgaT, putative K03475 ulaA; ascorbate PTS system EIIC component
D Spy49_0674 fruA; PTS system, fructose-specific IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202]
D Spy49_0673 fruK; Tagatose-6-phosphate kinase / 1-phosphofructokinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56]
C 03070 Bacterial secretion system [PATH:soz03070]
D Spy49_1704c Preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D Spy49_0421 Preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D Spy49_0068 secY; Preprotein translocase secY subunit K03076 secY; preprotein translocase subunit SecY
D Spy49_1624c Preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D Spy49_0208 Membrane protein oxaA 1 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
D Spy49_0291 oxaA; Membrane protein oxaA 2 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
D Spy49_1410c secA; Protein export cytoplasm protein SecA ATPase RNA helicase K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D Spy49_0482 ftsY; Signal recognition particle receptor protein FtsY alpha subunit K03110 ftsY; fused signal recognition particle receptor
D Spy49_0945c ffh; Signal recognition particle, subunit Ffh SRP54 K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:soz02020]
D Spy49_0987c pstS; Phosphate ABC transporter, periplasmic phosphate-binding protein pstS K02040 pstS; phosphate transport system substrate-binding protein
D Spy49_1821 degP; Endopeptidase degP K04771 degP; serine protease Do [EC:3.4.21.107]
D Spy49_0445 vicK; Two-component sensor histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
D Spy49_0444 vicR; Two-component response regulator K07668 vicR; two-component system, OmpR family, response regulator VicR
D Spy49_0001 dnaA; Chromosomal replication initiator protein dnaA K02313 dnaA; chromosomal replication initiator protein
D Spy49_1037c dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
D Spy49_1036c dltB; Protein dltB K03739 dltB; membrane protein involved in D-alanine export
D Spy49_1035c dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
D Spy49_1034c dltD; Protein dltD precursor K03740 dltD; D-alanine transfer protein
D Spy49_0979c ciaH; Putative histidine kinase protein K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
D Spy49_0980c ciaR; Transcriptional regulatory protein ciaR K14983 ciaR; two-component system, OmpR family, response regulator CiaR
D Spy49_1378c D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
D Spy49_0280 csrS; Transmembrane histidine kinase CsrS K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]
D Spy49_0279 csrR; Response regulator CsrR K18941 arlR; two-component system, OmpR family, response regulator ArlR
D Spy49_1676c Two-component system histidine kinase K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3]
D Spy49_1677c Two-component system response regulator K18987 irr; two-component system, OmpR family, response regulator Irr
D Spy49_0940c citC; Citrate (pro-3S)-lyase ligase K01910 citC; [citrate (pro-3S)-lyase] ligase [EC:6.2.1.22]
D Spy49_0934 citD; Putative citrate lyase, gamma subunit K01646 citD; citrate lyase subunit gamma (acyl carrier protein)
D Spy49_0936 citE; Citrate lyase beta chain K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34]
D Spy49_0937 citF; Citrate lyase alpha chain K01643 citF; citrate lyase subunit alpha / citrate CoA-transferase [EC:2.8.3.10]
D Spy49_0938 citX; Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase K05964 citX; holo-ACP synthase [EC:2.7.7.61]
D Spy49_0927c citG; Probable 2-(5-triphosphoribosyl)-3-dephosphocoenzyme-A synthase K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]
D Spy49_0864 NAD-dependent malic enzyme K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
D Spy49_0863 malP; Putative L-malate permease K11616 maeN; malate:Na+ symporter
D Spy49_1240c Histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D Spy49_0204 fasB; Putative histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D Spy49_0205 Putative histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D Spy49_0206 fasA; Response regulator FasA K07707 agrA; two-component system, LytTR family, response regulator AgrA
D Spy49_0256 comX1; ComX1 Alternate Sigma Factor K12296 comX1_2; competence protein ComX
D Spy49_1569c comX2; ComX2 alternate sigma factor K12296 comX1_2; competence protein ComX
D Spy49_0010 hypothetical protein K01467 ampC; beta-lactamase class C [EC:3.5.2.6]
D Spy49_1255c Putative two-component sensor histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
D Spy49_1254c Putative two-component response regulator K11618 liaR; two-component system, NarL family, response regulator LiaR
D Spy49_1577c salK; SalK K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK
D Spy49_1576c salR; Putative response regulator of salavaricin regulon K14989 salR; two-component system, NarL family, secretion system response regulator SalR
D Spy49_1550c glnA; Glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Spy49_0124 atoD.2; Acetate CoA-transferase alpha subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
D Spy49_1269 atoD1; Putative acetyl-CoA:acetoacetyl-CoA transferase A subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
D Spy49_1270 atoA; Putative acetyl-CoA:acetoacetyl-CoA transferase b subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]
D Spy49_0125 Butyrate-acetoacetate CoA-transferase, beta subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]
D Spy49_0121 atoE; Short-chain fatty acids transporter K02106 atoE; short-chain fatty acids transporter
D Spy49_1268 atoB; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0440 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0123 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_1228c Putative two-component sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
D Spy49_1202c yesM; Putative two-component sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
D Spy49_1227c Putative two-component sensor response regulator K07720 yesN; two-component system, response regulator YesN
D Spy49_0839 Putative two-component response regulator K07720 yesN; two-component system, response regulator YesN
D Spy49_1203c yesN; Putative two-component response regulator K07720 yesN; two-component system, response regulator YesN
D Spy49_0035 Low molecular weight protein tyrosine phosphatase K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:soz02024]
D Spy49_1273 luxS; Ribosylhomocysteinase / Autoinducer-2 production protein LuxS K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]
D Spy49_1654 trpG; Anthranilate synthase, amidotransferase-like component / Para-aminobenzoate synthase, amidotransferase component K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D Spy49_0441 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D Spy49_1240c Histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D Spy49_0204 fasB; Putative histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D Spy49_0205 Putative histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D Spy49_0206 fasA; Response regulator FasA K07707 agrA; two-component system, LytTR family, response regulator AgrA
D Spy49_0146 slo; Thiol-activated cytolysin K11031 slo; thiol-activated cytolysin
D Spy49_0979c ciaH; Putative histidine kinase protein K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
D Spy49_0980c ciaR; Transcriptional regulatory protein ciaR K14983 ciaR; two-component system, OmpR family, response regulator CiaR
D Spy49_0249 oppA; Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein oppA K15580 oppA; oligopeptide transport system substrate-binding protein
D Spy49_0250 oppB; Oligopeptide transport system permease protein K15581 oppB; oligopeptide transport system permease protein
D Spy49_0251 oppC; Oligopeptide transport system permease protein oppC K15582 oppC; oligopeptide transport system permease protein
D Spy49_0252 oppD; Oligopeptide transport ATP-binding protein oppD K15583 oppD; oligopeptide transport system ATP-binding protein
D Spy49_0253 oppF; Oligopeptide transport ATP-binding protein oppF K10823 oppF; oligopeptide transport system ATP-binding protein
D Spy49_0032 Transcriptional regulator, Cro/CI family K20342 comR; HTH-type transcriptional regulator, regulator for ComX
D Spy49_0256 comX1; ComX1 Alternate Sigma Factor K12296 comX1_2; competence protein ComX
D Spy49_1569c comX2; ComX2 alternate sigma factor K12296 comX1_2; competence protein ComX
D Spy49_0415 mutR; Putative positive transcriptional regulator K20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator
D Spy49_0449c Putative positive regulator K20374 rgg3; HTH-type transcriptional regulator, SHP3-responsive repressor
D Spy49_1660 dppA; Dipeptide-binding ABC transporter, periplasmic substrate-binding component K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D Spy49_1661 dppB; Dipeptide transport system permease protein dppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D Spy49_1662 dppC; Dipeptide transport system permease protein dppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D Spy49_1663 dppD; Dipeptide transport ATP-binding protein dppD K02031 ddpD; peptide/nickel transport system ATP-binding protein
D Spy49_1664 dppF; Dipeptide transport ATP-binding protein dppF K02032 ddpF; peptide/nickel transport system ATP-binding protein
D Spy49_1691 ropB; RopB K20375 ropB; HTH-type transcriptional regulator, pheromone-responsive regulator
D Spy49_1690c speB; Strepotococcal cysteine protease (Streptopain) / Streptococcal pyrogenic exotoxin B (SpeB) K01364 speB; streptopain [EC:3.4.22.10]
D Spy49_1322c lacD1; Tagatose 1,6-diphosphate aldolase K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40]
D Spy49_1587c lacD2; Tagatose 1,6-diphosphate aldolase K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40]
D Spy49_0208 Membrane protein oxaA 1 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
D Spy49_0291 oxaA; Membrane protein oxaA 2 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
D Spy49_1704c Preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D Spy49_0421 Preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D Spy49_0068 secY; Preprotein translocase secY subunit K03076 secY; preprotein translocase subunit SecY
D Spy49_1624c Preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D Spy49_1410c secA; Protein export cytoplasm protein SecA ATPase RNA helicase K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D Spy49_0482 ftsY; Signal recognition particle receptor protein FtsY alpha subunit K03110 ftsY; fused signal recognition particle receptor
D Spy49_0945c ffh; Signal recognition particle, subunit Ffh SRP54 K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly [PATH:soz02040]
D Spy49_0715 Putative ABC transporter K02424 tcyA; L-cystine transport system substrate-binding protein
D Spy49_0266 atmA; ABC transporter, substrate-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein
D Spy49_0609 rpoD; RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D Spy49_0563 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
D Spy49_0112 cbp; Putative collagen binding protein K13734 sfb1; fibronectin-binding protein 1
D Spy49_1684c sof; Serum opacity factor K13734 sfb1; fibronectin-binding protein 1
D Spy49_1683c sfbX49; Fibronectin-binding protein K13734 sfb1; fibronectin-binding protein 1
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance [PATH:soz01501]
D Spy49_0010 hypothetical protein K01467 ampC; beta-lactamase class C [EC:3.5.2.6]
D Spy49_0249 oppA; Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein oppA K15580 oppA; oligopeptide transport system substrate-binding protein
D Spy49_0250 oppB; Oligopeptide transport system permease protein K15581 oppB; oligopeptide transport system permease protein
D Spy49_0251 oppC; Oligopeptide transport system permease protein oppC K15582 oppC; oligopeptide transport system permease protein
D Spy49_0252 oppD; Oligopeptide transport ATP-binding protein oppD K15583 oppD; oligopeptide transport system ATP-binding protein
D Spy49_0253 oppF; Oligopeptide transport ATP-binding protein oppF K10823 oppF; oligopeptide transport system ATP-binding protein
D Spy49_1279 pbp1A; Multimodular transpeptidase-transglycosylase K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D Spy49_0086 pbp1b; Multimodular transpeptidase-transglycosylase K03693 pbp1b; penicillin-binding protein 1B
D Spy49_1706c pbp2A; Multimodular transpeptidase-transglycosylase K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4]
D Spy49_1291c ftsI; Cell division protein ftsI / Peptidoglycan synthetase K12556 pbp2X; penicillin-binding protein 2X
C 01502 Vancomycin resistance [PATH:soz01502]
D Spy49_1137c ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D Spy49_1408c alr; Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D Spy49_1136c murF; UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D Spy49_1290c mraY; Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D Spy49_1176c murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D Spy49_1378c D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:soz01503]
D Spy49_1821 degP; Endopeptidase degP K04771 degP; serine protease Do [EC:3.4.21.107]
D Spy49_0384c cypB; Putative cyclophilin-type protein K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D Spy49_1037c dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
D Spy49_1036c dltB; Protein dltB K03739 dltB; membrane protein involved in D-alanine export
D Spy49_1035c dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
D Spy49_1034c dltD; Protein dltD precursor K03740 dltD; D-alanine transfer protein
D Spy49_1690c speB; Strepotococcal cysteine protease (Streptopain) / Streptococcal pyrogenic exotoxin B (SpeB) K01364 speB; streptopain [EC:3.4.22.10]
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:soz01000]
C 01001 Protein kinases [BR:soz01001]
D Spy49_1257c Serine/threonine protein kinase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D Spy49_0445 vicK; Two-component sensor histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
D Spy49_0979c ciaH; Putative histidine kinase protein K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
D Spy49_0280 csrS; Transmembrane histidine kinase CsrS K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]
D Spy49_1676c Two-component system histidine kinase K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3]
D Spy49_1255c Putative two-component sensor histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
D Spy49_1577c salK; SalK K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK
D Spy49_0862c Putative two-component sensor histidine kinase K02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3]
D Spy49_1240c Histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D Spy49_0204 fasB; Putative histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D Spy49_0205 Putative histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D Spy49_1228c Putative two-component sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
D Spy49_1202c yesM; Putative two-component sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:soz01009]
D Spy49_1018c pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D Spy49_1259c pppL; Putative phosphoprotein phosphatase (pppL protein) K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16]
C 01002 Peptidases and inhibitors [BR:soz01002]
D Spy49_0647 lsp; Putative prolipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
D Spy49_1280c pepC; Aminopeptidase C K01372 BLMH; bleomycin hydrolase [EC:3.4.22.40]
D Spy49_1690c speB; Strepotococcal cysteine protease (Streptopain) / Streptococcal pyrogenic exotoxin B (SpeB) K01364 speB; streptopain [EC:3.4.22.10]
D Spy49_0425c pcp; Pyrrolidone-carboxylate peptidase K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3]
D Spy49_0949 guaA; GMP synthase - glutamine-hydrolyzing K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D Spy49_0871c Glutamine amidotransferase, class I K07010 K07010; putative glutamine amidotransferase
D Spy49_0015 Putative secreted protein Streptputative secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
D Spy49_0022 purF; Amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D Spy49_1015c glmS; Glucosamine--fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D Spy49_0906 Sortase K07284 srtA; sortase A [EC:3.4.22.70]
D Spy49_0116 NPQTN specific sortase B K08600 srtB; sortase B [EC:3.4.22.71]
D Spy49_0548 pepD; Probable dipeptidase A K08659 pepDA; dipeptidase [EC:3.4.-.-]
D Spy49_1105c hypothetical protein K07052 K07052; CAAX protease family protein
D Spy49_0573 sagE; Streptolysin S self-immunity protein (SagE) K07052 K07052; CAAX protease family protein
D Spy49_0981c pepN; Putative lysyl-aminopeptidase K01256 pepN; aminopeptidase N [EC:3.4.11.2]
D Spy49_1112c pepB; Group B oligopeptidase pepB K08602 pepF; oligoendopeptidase F [EC:3.4.24.-]
D Spy49_1735c pepO; Putative endopeptidase O K07386 pepO; putative endopeptidase [EC:3.4.24.-]
D Spy49_1378c D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
D Spy49_0844 Xaa-His dipeptidase K01274 pepV; beta-Ala-Xaa dipeptidase [EC:3.4.13.-]
D Spy49_0624 pepT; Tripeptide aminopeptidase K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]
D Spy49_1077c map; Methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D Spy49_0431c pepQ; Putative Xaa-Pro dipeptidase K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]
D Spy49_1422c pepP; Aminopeptidase YpdF (MP-, MA-, MS-, AP-, NP-specific) K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D Spy49_0013 ftsH; Cell division protein ftsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D Spy49_0101 pepA; Putative glutamyl-aminopeptidase K01261 pepA; glutamyl aminopeptidase [EC:3.4.11.7]
D Spy49_0277 htpX; Probable HtpX-like protease K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D Spy49_1620c eep; hypothetical protein K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
D Spy49_1821 degP; Endopeptidase degP K04771 degP; serine protease Do [EC:3.4.21.107]
D Spy49_0336 prtS; Putative cell envelope proteinase K01361 E3.4.21.96; lactocepin [EC:3.4.21.96]
D Spy49_1669c scpA; C5a peptidase precursor K08652 C5AP; C5a peptidase [EC:3.4.21.110]
D Spy49_0248c dacA; Penicillin-binding protein 7 precursor (PBP-7) (D-alanyl-D-alanine-endopeptidase) K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D Spy49_0849 dacA1; Penicillin-binding protein 7 precursor (PBP-7) (D-alanyl-D-alanine-endopeptidase) K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D Spy49_0323 clpP; ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
D Spy49_1451 pepXP; Xaa-Pro dipeptidyl-peptidase K01281 pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11]
D Spy49_1188c ATP-dependent protease La K07177 K07177; Lon-like protease
D Spy49_0944 Putative repressor protein K01356 lexA; repressor LexA [EC:3.4.21.88]
D Spy49_1438 spi; Putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D Spy49_1016c sipC; Putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D Spy49_0113 lepA-1; Putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D Spy49_0475 Microcin C7 self-immunity protein mccF K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]
D Spy49_0500 Putative protease K08303 prtC; U32 family peptidase [EC:3.4.-.-]
C 01003 Glycosyltransferases [BR:soz01003]
D Spy49_0434 Putative glucosyl transferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]
D Spy49_1804 hasA; hyaluronan synthase K00752 hasA; hyaluronan synthase [EC:2.4.1.212]
D Spy49_0433 Putative sugar transferase K13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208]
D Spy49_1279 pbp1A; Multimodular transpeptidase-transglycosylase K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D Spy49_0086 pbp1b; Multimodular transpeptidase-transglycosylase K03693 pbp1b; penicillin-binding protein 1B
D Spy49_1706c pbp2A; Multimodular transpeptidase-transglycosylase K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4]
D Spy49_0241 rgpG; Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]
C 01005 Lipopolysaccharide biosynthesis proteins [BR:soz01005]
D Spy49_0612 rgpAc; Putative rhamnosyltransferase K12996 rgpA; rhamnosyltransferase [EC:2.4.1.-]
D Spy49_0613 rgpBc; Rhamnosyltransferase K12997 rgpB; rhamnosyltransferase [EC:2.4.1.-]
D Spy49_0617 rgpEc; Putative glycosyltransferase K12998 rgpE; glucosyltransferase [EC:2.4.1.-]
D Spy49_0618 rgpFc; RgpFc protein K07272 rgpF; rhamnosyltransferase [EC:2.4.1.-]
D Spy49_0241 rgpG; Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]
D Spy49_0428c Putative sugar transferase K12999 rgpI; glucosyltransferase [EC:2.4.1.-]
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:soz01011]
D Spy49_0591 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D Spy49_1082c murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D Spy49_0856 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D Spy49_0287 murC1; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D Spy49_1177c murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D Spy49_0319c murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7]
D Spy49_1137c ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D Spy49_0951c murM2; Putative antimicrobial resistance factor K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10]
D Spy49_0518c murM.1; Putative peptidoglycan branched peptide synthesis protein, serine/alanine adding enzyme K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10]
D Spy49_0517c murN; Putative peptidoglycan branched peptide synthesis protein, alanine adding enzyme K12554 murN; alanine adding enzyme [EC:2.3.2.-]
D Spy49_1408c alr; Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D Spy49_0297 glr; Glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3]
D Spy49_0475 Microcin C7 self-immunity protein mccF K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]
D Spy49_1290c mraY; Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D Spy49_1176c murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D Spy49_0239 bacA; Putative undecaprenol kinase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D Spy49_0308 Putative phosphatase K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]
D Spy49_1279 pbp1A; Multimodular transpeptidase-transglycosylase K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D Spy49_0086 pbp1b; Multimodular transpeptidase-transglycosylase K03693 pbp1b; penicillin-binding protein 1B
D Spy49_1706c pbp2A; Multimodular transpeptidase-transglycosylase K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4]
D Spy49_1291c ftsI; Cell division protein ftsI / Peptidoglycan synthetase K12556 pbp2X; penicillin-binding protein 2X
D Spy49_0248c dacA; Penicillin-binding protein 7 precursor (PBP-7) (D-alanyl-D-alanine-endopeptidase) K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D Spy49_0849 dacA1; Penicillin-binding protein 7 precursor (PBP-7) (D-alanyl-D-alanine-endopeptidase) K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D Spy49_1378c D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
D Spy49_0015 Putative secreted protein Streptputative secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
D Spy49_0906 Sortase K07284 srtA; sortase A [EC:3.4.22.70]
D Spy49_0116 NPQTN specific sortase B K08600 srtB; sortase B [EC:3.4.22.71]
D Spy49_0289 Putative aminodeoxychorismate lyase K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]
C 01004 Lipid biosynthesis proteins [BR:soz01004]
D Spy49_1366c fabD; Malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D Spy49_1369c fabH; 3-oxoacyl-(acyl-carrier-protein) synthase, KASIII K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D Spy49_1364c fabF; 3-oxoacyl-(acyl-carrier-protein) synthase, KASII K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D Spy49_0372 Putative dehydrogenease / oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D Spy49_1365c fabG; 3-oxoacyl-(acyl-carrier protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D Spy49_1362c fabz; (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D Spy49_1367c fabK; Enoyl-(acyl-carrier-protein) reductase (FMN) K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
D Spy49_1371c phaB; Trans-2,cis-3-Decenoyl-ACP isomerase K18474 fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14]
D Spy49_0441 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D Spy49_0018 Fatty acid/phospholipid synthesis protein plsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D Spy49_0719c hypothetical protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D Spy49_1127c 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:soz01006]
D Spy49_1155c fps; Octaprenyl-diphosphate synthase / Dimethylallyltransferase / Geranyltranstransferase / Geranylgeranyl pyrophosphate synthetase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D Spy49_1622c uppS; Undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D Spy49_0730 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
C 01007 Amino acid related enzymes [BR:soz01007]
D Spy49_0203 gluS; Glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
D Spy49_0084 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Spy49_1813c trsA; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D Spy49_1604c cysS; Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Spy49_1762 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Spy49_0338 metS; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Spy49_1167c ileS; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Spy49_1215c valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Spy49_0152 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Spy49_0503c lysS; Lysyl-tRNA synthetase (class II) K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D Spy49_1768c aspS; Aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D Spy49_0473 Asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D Spy49_0544 asnS; Asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D Spy49_1769c hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Spy49_0476 hypothetical protein K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Spy49_1311c glyQ; Glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D Spy49_1310c glyS; Glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D Spy49_1358 serS; Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Spy49_1619c proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Spy49_0435 thrS; Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Spy49_1108c alaS; Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Spy49_0596 pheS; Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Spy49_0597 pheT; Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Spy49_1388c Aspartate aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]
D Spy49_0722 bcaT; Branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Spy49_1653 papB; Para-aminobenzoate synthase, aminase component / Aminodeoxychorismate lyase K03342 pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins [BR:soz00194]
D Spy49_0589 ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D Spy49_0588 ATP synthase beta chain K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D Spy49_0587 ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D Spy49_0586 ATP synthase alpha chain K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D Spy49_0585 ATP synthase delta chain K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D Spy49_0584 ATP synthase B chain K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D Spy49_0582 ATP synthase C chain K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D Spy49_0583 ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:soz03000]
D Spy49_1330 lacR1; Lactose phosphotransferase system repressor K02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor
D Spy49_1591 lacR2; Lactose phosphotransferase system repressor K02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor
D Spy49_0672 fruR; Putative transcriptional repressor K03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor
D Spy49_1027c malR; Putative maltose operon transcriptional repressor K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D Spy49_0432 ccpA; Catabolite control protein A K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D Spy49_1187c Ribose operon repressor K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D Spy49_0523c regR; Putative transcriptional regulator K02525 kdgR; LacI family transcriptional regulator, kdg operon repressor
D Spy49_1417 scrR; Putative sucrose operon repressor K03484 scrR; LacI family transcriptional regulator, sucrose operon repressor
D Spy49_1237c Putative transcription regulator K02103 araR; GntR family transcriptional regulator, arabinose operon transcriptional repressor
D Spy49_1738 Trehalose operon transcriptional repressor K03486 treR2; GntR family transcriptional regulator, trehalose operon transcriptional repressor
D Spy49_0947c Transcriptional regulator, GntR family K24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator
D Spy49_0550 Transcriptional regulator, GntR family K24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator
D Spy49_1551c glnR; Putative transcriptional regulator K03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor
D Spy49_0165 Ferric transport regulator protein K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator
D Spy49_1198c Transcriptional regulator, CrP/Fnr family K21828 arcR; CRP/FNR family transcriptional regulator, arginine deiminase pathway regulator
D Spy49_1774 cadX; Putative cadmium efflux system accessory K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor
D Spy49_1781 Conserved hypothetical protein K10947 K10947; PadR family transcriptional regulator
D Spy49_0380c Putative metal-dependent transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D Spy49_1085 birA; Biotin-protein ligase / Biotin operon repressor K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D Spy49_0032 Transcriptional regulator, Cro/CI family K20342 comR; HTH-type transcriptional regulator, regulator for ComX
D Spy49_0415 mutR; Putative positive transcriptional regulator K20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator
D Spy49_0449c Putative positive regulator K20374 rgg3; HTH-type transcriptional regulator, SHP3-responsive repressor
D Spy49_1691 ropB; RopB K20375 ropB; HTH-type transcriptional regulator, pheromone-responsive regulator
D Spy49_0228 purR; Putative purine operon repressor K09685 purR; HTH-type transcriptional regulator, purine operon repressor
D Spy49_0872c Redox-sensing transcriptional repressor rex K01926 rex; redox-sensing transcriptional repressor
D Spy49_1387c codY; GTP-sensing transcriptional pleiotropic repressor codY K03706 codY; transcriptional pleiotropic repressor
D Spy49_1597c Putative transcription regulator K07729 K07729; putative transcriptional regulator
D Spy49_1107c Transcriptional regulator, Cro/CI family K07729 K07729; putative transcriptional regulator
D Spy49_1518c Putative cro protein K07729 K07729; putative transcriptional regulator
D Spy49_0484 bglG; Putative transcription antiterminator K03488 licT; beta-glucoside operon transcriptional antiterminator
D Spy49_0159 Putative transcriptional regulator K03493 bglG1; transcriptional antiterminator
D Spy49_1047c Putative transcriptional antiterminator K03491 licR; probable licABCH operon transcriptional regulator
D Spy49_1822 parB; Chromosome partitioning protein parB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D Spy49_1153c Putative repressor protein K03402 argR; transcriptional regulator of arginine metabolism
D Spy49_1199 argR; Putative arginine repressor K03402 argR; transcriptional regulator of arginine metabolism
D Spy49_1761c Putative arginine repressor K03402 argR; transcriptional regulator of arginine metabolism
D Spy49_1376c hrcA; Heat-inducible transcription repressor hrcA K03705 hrcA; heat-inducible transcriptional repressor
D Spy49_1718c ctsR; Putative transcriptional regulator K03708 ctsR; transcriptional regulator of stress and heat shock response
D Spy49_0650 pyrR; Uracil phosphoribosyltransferase / Pyrimidine operon regulatory protein pyrR K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]
D Spy49_0281 nrdR.1; Ribonucleotide reductase transcriptional regulator NrdR K07738 nrdR; transcriptional repressor NrdR
D Spy49_0256 comX1; ComX1 Alternate Sigma Factor K12296 comX1_2; competence protein ComX
D Spy49_1569c comX2; ComX2 alternate sigma factor K12296 comX1_2; competence protein ComX
C 03021 Transcription machinery [BR:soz03021]
D Spy49_0074 rpoA; DNA-directed RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D Spy49_0087 rpoB; DNA-directed RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D Spy49_0088 rpoC; DNA-directed RNA polymerase beta subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D Spy49_1562c rpoE; DNA-directed RNA polymerase delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
D Spy49_1263c DNA-directed RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D Spy49_0609 rpoD; RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor
D Spy49_1340c nusA; Transcription termination protein NusA K02600 nusA; transcription termination/antitermination protein NusA
D Spy49_1418c nusB; N utilization substance B-like protein K03625 nusB; transcription antitermination protein NusB
D Spy49_0143 nusG; Transcription antitermination protein NusG K02601 nusG; transcription termination/antitermination protein NusG
D Spy49_0290 greA; Transcription elongation factor GreA K03624 greA; transcription elongation factor GreA
C 03019 Messenger RNA biogenesis [BR:soz03019]
D Spy49_0447 acpA; Ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D Spy49_1549 hypothetical protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D Spy49_0801 hypothetical protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D Spy49_1266c hypothetical protein K18682 rny; ribonucrease Y [EC:3.1.-.-]
D Spy49_0422 vacB; Putative exoribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D Spy49_0227 cbf; Putative CMP-binding factor K03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-]
D Spy49_1132c deaD1; Putative ATP-dependent RNA helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D Spy49_1289c Putative ATP-dependent RNA helicase K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7]
D Spy49_0563 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Spy49_1608c pnp; Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D Spy49_1018c pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D Spy49_1374c dnaK; Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK
D Spy49_1715c groEL; Heat shock protein 60 family chaperone GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Spy49_0545 hypothetical protein K06958 rapZ; RNase adapter protein RapZ
C 03041 Spliceosome
C 03011 Ribosome [BR:soz03011]
D Spy49_0724 rpsA; SSU ribosomal protein S1p K02945 RP-S1; small subunit ribosomal protein S1
D Spy49_1733 rpsB; SSU ribosomal protein S2p (SAe) K02967 RP-S2; small subunit ribosomal protein S2
D Spy49_0053 rpsC; SSU ribosomal protein S3p (S3e) K02982 RP-S3; small subunit ribosomal protein S3
D Spy49_1786c rpsD; SSU ribosomal protein S4p (S9e) K02986 RP-S4; small subunit ribosomal protein S4
D Spy49_0065 rpsE; SSU ribosomal protein S5p (S2e) K02988 RP-S5; small subunit ribosomal protein S5
D Spy49_1428c rpsF; SSU ribosomal protein S6p K02990 RP-S6; small subunit ribosomal protein S6
D Spy49_0231 rpsG; SSU ribosomal protein S7p (S5e) K02992 RP-S7; small subunit ribosomal protein S7
D Spy49_0061 rpsH; SSU ribosomal protein S8p (S15Ae) K02994 RP-S8; small subunit ribosomal protein S8
D Spy49_1595c rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D Spy49_0044 rpsJ; SSU ribosomal protein S10p (S20e) K02946 RP-S10; small subunit ribosomal protein S10
D Spy49_0073 rpsK; SSU ribosomal protein S11p (S14e) K02948 RP-S11; small subunit ribosomal protein S11
D Spy49_0230 rpsL; SSU ribosomal protein S12p (S23e) K02950 RP-S12; small subunit ribosomal protein S12
D Spy49_0072 rpsM; SSU ribosomal protein S13p (S18e) K02952 RP-S13; small subunit ribosomal protein S13
D Spy49_1544 rpsN2; SSU ribosomal protein S14p (S29e) K02954 RP-S14; small subunit ribosomal protein S14
D Spy49_0060 rpsN.1; SSU ribosomal protein S14p (S29e) K02954 RP-S14; small subunit ribosomal protein S14
D Spy49_1613c rpsO; SSU ribosomal protein S15p (S13e) K02956 RP-S15; small subunit ribosomal protein S15
D Spy49_0659 rpsP; SSU ribosomal protein S16p K02959 RP-S16; small subunit ribosomal protein S16
D Spy49_0056 rpsQ; SSU ribosomal protein S17p (S11e) K02961 RP-S17; small subunit ribosomal protein S17
D Spy49_1426c rpsR; SSU ribosomal protein S18p K02963 RP-S18; small subunit ribosomal protein S18
D Spy49_0050 rpsS; SSU ribosomal protein S19p (S15e) K02965 RP-S19; small subunit ribosomal protein S19
D Spy49_0978 prsT; SSU ribosomal protein S20p K02968 RP-S20; small subunit ribosomal protein S20
D Spy49_0606 rpsU; SSU ribosomal protein S21p K02970 RP-S21; small subunit ribosomal protein S21
D Spy49_0388 rplA; LSU ribosomal protein L1p (L10Ae) K02863 RP-L1; large subunit ribosomal protein L1
D Spy49_0049 rplB; LSU ribosomal protein L2p (L8e) K02886 RP-L2; large subunit ribosomal protein L2
D Spy49_0045 rplC; LSU ribosomal protein L3p (L3e) K02906 RP-L3; large subunit ribosomal protein L3
D Spy49_0046 rplD; LSU ribosomal protein L4p (L1e) K02926 RP-L4; large subunit ribosomal protein L4
D Spy49_0059 rplE; LSU ribosomal protein L5p (L11e) K02931 RP-L5; large subunit ribosomal protein L5
D Spy49_0062 rplF; LSU ribosomal protein L6p (L9e) K02933 RP-L6; large subunit ribosomal protein L6
D Spy49_1789c rplI; LSU ribosomal protein L9p K02939 RP-L9; large subunit ribosomal protein L9
D Spy49_0846 rplJ; LSU ribosomal protein L10p (P0) K02864 RP-L10; large subunit ribosomal protein L10
D Spy49_0387 rplK; LSU ribosomal protein L11p (L12e) K02867 RP-L11; large subunit ribosomal protein L11
D Spy49_0848 rplL; LSU ribosomal protein L7/L12 (L23e) K02935 RP-L7; large subunit ribosomal protein L7/L12
D Spy49_1596c rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D Spy49_0057 rplN; LSU ribosomal protein L14p (L23e) K02874 RP-L14; large subunit ribosomal protein L14
D Spy49_0067 rplO; LSU ribosomal protein L15p (L27Ae) K02876 RP-L15; large subunit ribosomal protein L15
D Spy49_0054 rplP; LSU ribosomal protein L16p (L10e) K02878 RP-L16; large subunit ribosomal protein L16
D Spy49_0075 rplQ; LSU ribosomal protein L17p K02879 RP-L17; large subunit ribosomal protein L17
D Spy49_0064 rplR; LSU ribosomal protein L18p (L5e) K02881 RP-L18; large subunit ribosomal protein L18
D Spy49_0558 rplS; LSU ribosomal protein L19p K02884 RP-L19; large subunit ribosomal protein L19
D Spy49_0631 rplT; LSU ribosomal protein L20p K02887 RP-L20; large subunit ribosomal protein L20
D Spy49_0643 rplU; LSU ribosomal protein L21p K02888 RP-L21; large subunit ribosomal protein L21
D Spy49_0052 rplV; LSU ribosomal protein L22p (L17e) K02890 RP-L22; large subunit ribosomal protein L22
D Spy49_0048 rplW; LSU ribosomal protein L23p (L23Ae) K02892 RP-L23; large subunit ribosomal protein L23
D Spy49_0058 rplX; LSU ribosomal protein L24p (L26e) K02895 RP-L24; large subunit ribosomal protein L24
D Spy49_0645 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D Spy49_1558c rpmB; LSU ribosomal protein L28p K02902 RP-L28; large subunit ribosomal protein L28
D Spy49_0055 rpmC; LSU ribosomal protein L29p (L35e) K02904 RP-L29; large subunit ribosomal protein L29
D Spy49_0066 rpmD; LSU ribosomal protein L30p (L7e) K02907 RP-L30; large subunit ribosomal protein L30
D Spy49_0552c rpmE; LSU ribosomal protein L31p K02909 RP-L31; large subunit ribosomal protein L31
D Spy49_1770 rpmF; LSU ribosomal protein L32p K02911 RP-L32; large subunit ribosomal protein L32
D Spy49_0420 LSU ribosomal protein L33p K02913 RP-L33; large subunit ribosomal protein L33
D Spy49_1705c rpmG1; LSU ribosomal protein L33p K02913 RP-L33; large subunit ribosomal protein L33
D Spy49_1771 rpmG2; LSU ribosomal protein L33p K02913 RP-L33; large subunit ribosomal protein L33
D Spy49_0210 rpmH; LSU ribosomal protein L34p K02914 RP-L34; large subunit ribosomal protein L34
D Spy49_0630 rpmI; LSU ribosomal protein L35p K02916 RP-L35; large subunit ribosomal protein L35
D Spy49_0071 rpmJ; LSU ribosomal protein L36p K02919 RP-L36; large subunit ribosomal protein L36
D Spy49_rRNA5s1 5S Subunit Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_rRNA5s3 5S Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_rRNA5s2 5S Subunit Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_rRNA5s5 5S Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_rRNA5s4 5S Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_rRNA5s6 5S Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_rRNA16s5 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA16s6 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA16s4 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA16s2 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA16s1 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA16s3 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA23s2 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA23s4 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA23s1 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA23s5 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA23s6 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA23s3 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:soz03009]
D Spy49_0447 acpA; Ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D Spy49_0403 era; GTP-binding protein Era K03595 era; GTPase
D Spy49_1053c GTP-binding protein Obg K03979 obgE; GTPase [EC:3.6.5.-]
D Spy49_1340c nusA; Transcription termination protein NusA K02600 nusA; transcription termination/antitermination protein NusA
D Spy49_1418c nusB; N utilization substance B-like protein K03625 nusB; transcription antitermination protein NusB
D Spy49_0143 nusG; Transcription antitermination protein NusG K02601 nusG; transcription termination/antitermination protein NusG
D Spy49_1064c rsuA; Putative 16S pseudouridylate synthase K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]
D Spy49_1114c Putative 16S pseudouridylate synthetase K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]
D Spy49_0221 ksgA; Dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D Spy49_1260c sunL; Putative RNA-binding Sun protein K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]
D Spy49_0976c Conserved hypothetical protein K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]
D Spy49_1190c Conserved hypothetical protein K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]
D Spy49_1637c hypothetical protein K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]
D Spy49_0275 gidB; Methyltransferase gidB K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D Spy49_1293c mraW; S-adenosyl-methyltransferase mraW K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
D Spy49_0330 Tetrapyrrole methylase family protein K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]
D Spy49_1154c Putative hemolysin K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]
D Spy49_1601c 23S rRNA methyltransferase K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]
D Spy49_1820c hypothetical protein K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]
D Spy49_0633 Conserved hypothetical protein K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]
D Spy49_1185c hypothetical protein K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]
D Spy49_1072c Putative RNA methyltransferase K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]
D Spy49_0304 rluB; Putative ribosomal large subunit pseudouridine synthase K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]
D Spy49_1709 Putative ribosomal large subunit pseudouridine synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D Spy49_0648 Putative ribosomal large subunit pseudouridine synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D Spy49_0879 rluD; Ribosomal large subunit pseudouridine synthase, RluD subfamily K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D Spy49_1546c Ribosomal-protein-S18p-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D Spy49_0665 rimM; 16S rRNA processing protein RimM K02860 rimM; 16S rRNA processing protein RimM
D Spy49_1638c Ribosomal protein L11 methyltransferase K02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]
D Spy49_1750c Putative Holliday junction resolvase K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]
D Spy49_1603c Conserved hypothetical protein K11145 mrnC; mini-ribonuclease III [EC:3.1.26.-]
D Spy49_1132c deaD1; Putative ATP-dependent RNA helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D Spy49_1289c Putative ATP-dependent RNA helicase K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7]
D Spy49_0223 engC; Probable GTPase engC K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]
D Spy49_0284 engA; GTP-binding protein EngA K03977 engA; GTPase
D Spy49_0912 GTP-binding protein K14540 rbgA; ribosome biogenesis GTPase A
D Spy49_0731 hflX; GTP-binding protein HflX K03665 hflX; GTPase
D Spy49_0258 GTP-binding protein K06948 yqeH; 30S ribosome assembly GTPase
D Spy49_0896 Sua5/YciO/YrdC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D Spy49_1632c relA; GTP pyrophosphokinase / Guanosine-3,5-bis(Diphosphate) 3-pyrophosphohydrolase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D Spy49_1336c rbfA; Ribosome-binding factor A K02834 rbfA; ribosome-binding factor A
D Spy49_1341c transcription termination protein NusA-like protein K09748 rimP; ribosome maturation factor RimP
D Spy49_1809 hypothetical protein K14761 rlbA; ribosome-associated protein
D Spy49_0262 hypothetical protein K09710 ybeB; ribosome-associated protein
D Spy49_0401 hypothetical protein K07042 ybeY; probable rRNA maturation factor
D Spy49_0259 hypothetical protein K07574 yhbY; RNA-binding protein
D Spy49_1247c Ribosomal subunit interface protein K05808 hpf; ribosome hibernation promoting factor
D Spy49_0004 GTP-binding and nucleic acid-binding protein YchF K06942 ychF; ribosome-binding ATPase
D Spy49_0278 hypothetical protein K07040 yceD; DUF177 domain-containing protein
C 03016 Transfer RNA biogenesis [BR:soz03016]
D Spy49_0733 Ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D Spy49_0682 papS; tRNA nucleotidyltransferase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
D Spy49_1619c proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Spy49_1167c ileS; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Spy49_0152 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Spy49_0338 metS; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Spy49_1762 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Spy49_0503c lysS; Lysyl-tRNA synthetase (class II) K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D Spy49_1768c aspS; Aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D Spy49_1108c alaS; Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Spy49_0473 Asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D Spy49_0544 asnS; Asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D Spy49_0435 thrS; Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Spy49_1358 serS; Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Spy49_1604c cysS; Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Spy49_1215c valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Spy49_1769c hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Spy49_0476 hypothetical protein K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Spy49_0596 pheS; Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Spy49_0597 pheT; Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Spy49_0084 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Spy49_1813c trsA; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D Spy49_1631c dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D Spy49_1346 hit; Putative cell-cycle regulation histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D Spy49_1342c tRNA(m7G46)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D Spy49_1568c truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D Spy49_0993c truB; tRNA pseudouridine 55 synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D Spy49_0640 nifS; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Spy49_0874c Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Spy49_0896 Sua5/YciO/YrdC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D Spy49_0730 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D Spy49_0845c trmE; GTPase and tRNA-U34 5-formylation enzyme TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D Spy49_1791c gidA; Glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D Spy49_0207 rnpA; Ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D Spy49_1311c glyQ; Glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D Spy49_1310c glyS; Glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D Spy49_0203 gluS; Glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
D Spy49_0506c Putative transcription regulator K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
D Spy49_0185 Cytosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
D Spy49_0109c putative transcriptional regulator K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D Spy49_0922 gid; Gid-like Protein K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]
D Spy49_0667 trmD; tRNA (guanine-N1)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D Spy49_0739 hypothetical protein K06967 trmK; tRNA (adenine22-N1)-methyltransferase [EC:2.1.1.217]
D Spy49_0306 Putative rRNA methylase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D Spy49_0293 Putative rRNA methylase K03437 spoU; RNA methyltransferase, TrmH family
D Spy49_1793c trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D Spy49_1116 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D Spy49_0535 hypothetical protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D Spy49_0198 hypothetical protein K09765 queH; epoxyqueuosine reductase [EC:1.17.99.6]
D Spy49_0181 tgt; tRNA-guanine transglycosylase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D Spy49_0641 thiI; Probable thiamine biosynthesis protein thiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D Spy49_0011 mesJ; tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D Spy49_1547c Inactive metal-dependent protease-like protein; putative molecular chaperone K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D Spy49_1545c gcp; Putative glycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D Spy49_1350c Conserved hypothetical protein K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D Spy49_0264 Conserved hypothetical protein K27343 tmcAL; tRNA(Met) cytidine acetate ligase [EC:6.3.4.-]
D Spy49_0422 vacB; Putative exoribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D Spy49_1608c pnp; Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C 03012 Translation factors [BR:soz03012]
D Spy49_1337c infB; Translation initiation factor 2 K02519 infB; translation initiation factor IF-2
D Spy49_0629 infC; Translation initiation factor 3 K02520 infC; translation initiation factor IF-3
D Spy49_0805 Putative ABC transporter K06158 ABCF3; ATP-binding cassette, subfamily F, member 3
D Spy49_1734 tsf; Translation elongation factor Ts K02357 tsf; elongation factor Ts
D Spy49_0515 tufA; Translation elongation factor Tu K02358 tuf; elongation factor Tu
D Spy49_0233 fusA; Elongation factor G K02355 fusA; elongation factor G
D Spy49_0894 prfA; Peptide chain release factor 1 K02835 prfA; peptide chain release factor 1
D Spy49_0391 rrf; Ribosome recycling factor K02838 frr; ribosome recycling factor
D Spy49_0895 hemK; Putative protoporphyrinogen oxidase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D Spy49_0005 pth; Peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]
D Spy49_0070 infA; Translation initiation factor 1 K02518 infA; translation initiation factor IF-1
D Spy49_1420c efp; Translation elongation factor P K02356 efp; elongation factor P
D Spy49_0536 prfB; Peptide chain release factor 2 K02836 prfB; peptide chain release factor 2
D Spy49_1133c prfC; Peptide chain release factor 3 K02837 prfC; peptide chain release factor 3
C 03110 Chaperones and folding catalysts [BR:soz03110]
D Spy49_1717c clpC; Putative endopeptidase Clp ATP-binding chain C K03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC
D Spy49_1164 clpE; Putative ATP-dependent protease K03697 clpE; ATP-dependent Clp protease ATP-binding subunit ClpE
D Spy49_0703c clpL; Putative ATP-dependent Clp proteinase K04086 clpL; ATP-dependent Clp protease ATP-binding subunit ClpL
D Spy49_0700 clpX; ATP-dependent Clp protease ATP-binding subunit clpX K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
D Spy49_1374c dnaK; Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK
D Spy49_1715c groEL; Heat shock protein 60 family chaperone GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Spy49_1372c dnaJ; heat-shock (chaperone) DnaJ protein K03686 dnaJ; molecular chaperone DnaJ
D Spy49_0110c 33 kDa chaperonin K04083 hslO; molecular chaperone Hsp33
D Spy49_1375c grpE; putative Hsp-70 cofactor GrpE protein K03687 GRPE; molecular chaperone GrpE
D Spy49_1716c groES; Heat shock protein 60 family co-chaperone GroES K04078 groES; chaperonin GroES
D Spy49_1821 degP; Endopeptidase degP K04771 degP; serine protease Do [EC:3.4.21.107]
D Spy49_0013 ftsH; Cell division protein ftsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D Spy49_0583 ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D Spy49_0336 prtS; Putative cell envelope proteinase K01361 E3.4.21.96; lactocepin [EC:3.4.21.96]
D Spy49_1669c scpA; C5a peptidase precursor K08652 C5AP; C5a peptidase [EC:3.4.21.110]
D Spy49_0384c cypB; Putative cyclophilin-type protein K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D Spy49_1253c Hydrolase, haloacid dehalogenase family/peptidyl-prolyl cis-trans isomerase, cyclophilin type K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D Spy49_1687c ropA; Peptidylproline cis-trans-isomerase K07533 prsA; foldase protein PrsA [EC:5.2.1.8]
D Spy49_1109c prtM1; Foldase protein prsA 1 precursor K07533 prsA; foldase protein PrsA [EC:5.2.1.8]
D Spy49_1432c trx2; Thioredoxin reductase K03671 TXN; thioredoxin
C 04131 Membrane trafficking [BR:soz04131]
D Spy49_1239 Alpha-mannosidase K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
D Spy49_0234 plr; NAD-dependent glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D Spy49_1143c gpmA; Phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D Spy49_1017c pyk; Putatove pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
C 04121 Ubiquitin system
C 03051 Proteasome
C 03032 DNA replication proteins [BR:soz03032]
D Spy49_1147c DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D Spy49_0001 dnaA; Chromosomal replication initiator protein dnaA K02313 dnaA; chromosomal replication initiator protein
D Spy49_1788c dnaC; Replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D Spy49_1506c DNA replication protein dnaC K02315 dnaC; DNA replication protein DnaC
D Spy49_0608 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D Spy49_0282 dnaB; Putative chromosome replication initiation protein/membrane attachment protein K03346 dnaB; replication initiation and membrane attachment protein
D Spy49_0283 dnaI; Helicase loader DnaI K11144 dnaI; primosomal protein DnaI
D Spy49_1427c ssb2; Single-strand binding protein 2 K03111 ssb; single-strand DNA-binding protein
D Spy49_1500c Single-strand binding protein 3 K03111 ssb; single-strand DNA-binding protein
D Spy49_0107 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D Spy49_1019c dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D Spy49_1618c polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
D Spy49_0002 dnaN; Beta subunit of DNA polymerase III K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D Spy49_1123c holA; DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D Spy49_0327 DNA polymerase III delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D Spy49_1534c dnaQ; Putative DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D Spy49_1087c dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D Spy49_0913 rnh; Ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Spy49_1437 Ribonuclease HIII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4]
D Spy49_0163 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D Spy49_0580 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Spy49_0905 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D Spy49_0560 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D Spy49_0721 parC; Topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D Spy49_0720 parE; Topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D Spy49_0915 topA; Putative DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:soz03036]
D Spy49_0447 acpA; Ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D Spy49_1147c DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D Spy49_0001 dnaA; Chromosomal replication initiator protein dnaA K02313 dnaA; chromosomal replication initiator protein
D Spy49_1183c Putative peroxide resistance protein K04047 dps; starvation-inducible DNA-binding protein
D Spy49_0448 smc; Putative chromosome segregation SMC K03529 smc; chromosome segregation protein
D Spy49_0302 Segregation and condensation protein A K05896 scpA; segregation and condensation protein A
D Spy49_0303 Segregation and condensation protein B K06024 scpB; segregation and condensation protein B
D Spy49_1174c ftsA; Cell division protein ftsA K03590 ftsA; cell division protein FtsA
D Spy49_0009 divIC; Putative cell division protein K13052 divIC; cell division protein DivIC
D Spy49_0537 ftsE; Cell division transporter, ATP-binding protein ftsE K09812 ftsE; cell division transport system ATP-binding protein
D Spy49_0385 ftsK; Cell division protein ftsK K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family
D Spy49_1292c ftsL; Cell division protein ftsL K03586 ftsL; cell division protein FtsL
D Spy49_1175c ftsQ; Cell division protein ftsQ K03589 ftsQ; cell division protein FtsQ
D Spy49_0514 ftsW; Cell division protein ftsW K03588 ftsW; cell division protein FtsW
D Spy49_0538 ftsX; Cell division protein ftsX K09811 ftsX; cell division transport system permease protein
D Spy49_1173c ftsZ; Cell division protein ftsZ K03531 ftsZ; cell division protein FtsZ
D Spy49_0561 ezrA; Septation ring formation regulator ezrA K06286 ezrA; septation ring formation regulator
D Spy49_1168c divIVA; Cell-division initiation protein K04074 divIVA; cell division initiation protein
D Spy49_1171c Conserved hypothetical protein K09772 sepF; cell division inhibitor SepF
D Spy49_1822 parB; Chromosome partitioning protein parB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D Spy49_0721 parC; Topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D Spy49_0720 parE; Topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D Spy49_1791c gidA; Glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D Spy49_0275 gidB; Methyltransferase gidB K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D Spy49_0922 gid; Gid-like Protein K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]
D Spy49_0701 engB; GTP-binding protein EngB K03978 engB; GTP-binding protein
D Spy49_0547 Conserved hypothetical protein K09762 whiA; cell division protein WhiA
C 03400 DNA repair and recombination proteins [BR:soz03400]
D Spy49_1160c phr; Putative deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D Spy49_0717 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
D Spy49_1430 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D Spy49_0738 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D Spy49_1165 mutT; MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Spy49_0793 mutX; Putative 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Spy49_1640c nudB; MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Spy49_0199 dut; Putative deoxyuridine 5-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Spy49_1755c tag; DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
D Spy49_0416 fpg; Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D Spy49_0334c exoA; Putative 3-exo-deoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D Spy49_0735 recJ; Single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Spy49_0580 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Spy49_0163 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D Spy49_1423c uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
D Spy49_1039c uvrB; Excinuclease ABC (Subunit B), helicase subunit of the DNA excision repair complex K03702 uvrB; excinuclease ABC subunit B
D Spy49_0842 uvrC; Putative excinuclease ABC K03703 uvrC; excinuclease ABC subunit C
D Spy49_1007c pcrA; Putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D Spy49_0087 rpoB; DNA-directed RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D Spy49_0088 rpoC; DNA-directed RNA polymerase beta subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D Spy49_0074 rpoA; DNA-directed RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D Spy49_1562c rpoE; DNA-directed RNA polymerase delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
D Spy49_1263c DNA-directed RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D Spy49_0006 trcF; Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D Spy49_1759c mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Spy49_1434c mutS2; Putative DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2
D Spy49_1758c mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Spy49_1157c xseA; Probable exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D Spy49_1156c xseB; Probable exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D Spy49_1019c dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D Spy49_1618c polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
D Spy49_0002 dnaN; Beta subunit of DNA polymerase III K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D Spy49_1123c holA; DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D Spy49_0327 DNA polymerase III delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D Spy49_1534c dnaQ; Putative DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D Spy49_1087c dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D Spy49_1427c ssb2; Single-strand binding protein 2 K03111 ssb; single-strand DNA-binding protein
D Spy49_1500c Single-strand binding protein 3 K03111 ssb; single-strand DNA-binding protein
D Spy49_0107 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D Spy49_1439 recD; Exodeoxyribonuclease V alpha chain K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
D Spy49_1753c recA; RecA protein K03553 recA; recombination protein RecA
D Spy49_1756c ruvA; Holliday junction DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
D Spy49_0033 ruvB; Holliday junction DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D Spy49_1262c priA; Arrested fork binding K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D Spy49_0200 radA; RadA-like DNA repair protein K04485 radA; DNA repair protein RadA/Sms
D Spy49_1810 recF; Recombination protein F K03629 recF; DNA replication and repair protein RecF
D Spy49_1394c recG; Putative ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D Spy49_0017 recO; DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O)
D Spy49_1138c recR; Recombination protein recR K06187 recR; recombination protein RecR
D Spy49_1152c recN; Putative DNA repair and genetic recombination protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D Spy49_1278 recU; Recombination protein U-like protein K03700 recU; recombination protein U
D Spy49_0604 rexA; Putative ATP-dependent exonuclease, subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
D Spy49_0603 rexB; Putative ATP-dependent exonuclease, subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Spy49_1208c hypothetical protein K15342 cas1; CRISP-associated protein Cas1
D Spy49_0825 Lipoyl-binding domain protein K15342 cas1; CRISP-associated protein Cas1
D Spy49_0418 hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
D Spy49_0905 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D Spy49_0560 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D Spy49_0915 topA; Putative DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D Spy49_1147c DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D Spy49_1441c dinP; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D Spy49_0944 Putative repressor protein K01356 lexA; repressor LexA [EC:3.4.21.88]
D Spy49_1242 recX; Regulatory protein recX K03565 recX; regulatory protein
D Spy49_0541 dinG; DNA polymerase III, epsilon subunit/ATP-dependent helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D Spy49_0341 nrdE.2; Ribonucleotide reductase of class Ib (aerobic), alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Spy49_1097 nrdE1; Ribonucleotide reductase of class Ib (aerobic), alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Spy49_0339 nrdF.2; Ribonucleotide reductase of class Ib (aerobic), beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D Spy49_1099 Ribonucleotide reductase of class Ib (aerobic), beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D Spy49_0554c hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
C 03029 Mitochondrial biogenesis [BR:soz03029]
D Spy49_1337c infB; Translation initiation factor 2 K02519 infB; translation initiation factor IF-2
D Spy49_0629 infC; Translation initiation factor 3 K02520 infC; translation initiation factor IF-3
D Spy49_1734 tsf; Translation elongation factor Ts K02357 tsf; elongation factor Ts
D Spy49_0515 tufA; Translation elongation factor Tu K02358 tuf; elongation factor Tu
D Spy49_0233 fusA; Elongation factor G K02355 fusA; elongation factor G
D Spy49_0403 era; GTP-binding protein Era K03595 era; GTPase
D Spy49_0084 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Spy49_0152 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Spy49_1768c aspS; Aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D Spy49_1762 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Spy49_1383c gatA; Aspartyl-tRNA(Asn) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D Spy49_1382c gatB; Aspartyl-tRNA(Asn) amidotransferase subunit B Glutamyl-tRNA(Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D Spy49_1384c gatC; Aspartyl-tRNA(Asn) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D Spy49_1427c ssb2; Single-strand binding protein 2 K03111 ssb; single-strand DNA-binding protein
D Spy49_1500c Single-strand binding protein 3 K03111 ssb; single-strand DNA-binding protein
D Spy49_0107 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D Spy49_1374c dnaK; Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK
D Spy49_1375c grpE; putative Hsp-70 cofactor GrpE protein K03687 GRPE; molecular chaperone GrpE
D Spy49_1715c groEL; Heat shock protein 60 family chaperone GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Spy49_1716c groES; Heat shock protein 60 family co-chaperone GroES K04078 groES; chaperonin GroES
D Spy49_1372c dnaJ; heat-shock (chaperone) DnaJ protein K03686 dnaJ; molecular chaperone DnaJ
D Spy49_0640 nifS; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Spy49_0874c Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Spy49_0208 Membrane protein oxaA 1 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
D Spy49_0291 oxaA; Membrane protein oxaA 2 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:soz02000]
D Spy49_0194 Putative ABC transporter, ATP-binding protein K18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump
D Spy49_0195 ABC transporter, ATP-binding/permease protein K18892 patB; ATP-binding cassette, subfamily B, multidrug efflux pump
D Spy49_0901 ABC transporter, ATP-binding/permease protein K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump
D Spy49_0902 Putative ABC transporter K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump
D Spy49_1400c cycD; Putative ABC transporter K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial
D Spy49_1398c cycC; Putative ABC transporter K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial
D Spy49_0683 Putative ABC transporter K15738 uup; ABC transport system ATP-binding/permease protein
D Spy49_0840 Iron ABC transporter, iron-binding protein K02012 afuA; iron(III) transport system substrate-binding protein
D Spy49_0860 potD; ABC transporter, periplasmic spermidine putrescine-binding protein potD K11069 potD; spermidine/putrescine transport system substrate-binding protein
D Spy49_0859 potC; Spermidine Putrescine ABC transporter permease component potC K11070 potC; spermidine/putrescine transport system permease protein
D Spy49_0858 potB; Spermidine Putrescine ABC transporter permease component potB K11071 potB; spermidine/putrescine transport system permease protein
D Spy49_0857 potA; Spermidine Putrescine transport ATP-binding protein potA K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11]
D Spy49_0162 opuABC; L-proline Glycine Betaine ABC transport system permease protein proW K02001 proW; glycine betaine/proline transport system permease protein
D Spy49_0161 opuAA; L-proline Glycine Betaine ABC transport ATP-binding protein proV K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9]
D Spy49_0884 proX; L-proline glycine betaine binding ABC transporter protein proX / Osmotic adaptation K05845 opuC; osmoprotectant transport system substrate-binding protein
D Spy49_0883 proV; L-proline Glycine Betaine ABC transport ATP-binding protein proV K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]
D Spy49_1628c msmK; Sugar ABC transporter, ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D Spy49_1028 malE; Maltose maltodextrin ABC transporter, substrate binding periplasmic protein malE K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein
D Spy49_1029 malF; Maltose transport system permease protein malF K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D Spy49_1030 malG; Maltose transport system permease protein malG K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D Spy49_1230c ABC transporter, substrate-binding protein K17318 lplA; putative aldouronate transport system substrate-binding protein
D Spy49_1233c Putative sugar-binding transport protein K17319 lplB; putative aldouronate transport system permease protein
D Spy49_1231c ABC transporter, permease protein K17320 lplC; putative aldouronate transport system permease protein
D Spy49_0974c Putative lipoprotein K07335 bmpA; basic membrane protein A and related proteins
D Spy49_0142 Putative ABC transporter K07335 bmpA; basic membrane protein A and related proteins
D Spy49_0972c Putative sugar ABC transporter K23535 nupB; general nucleoside transport system permease protein
D Spy49_0971c Putative sugar ABC transporter K23536 nupC; general nucleoside transport system permease protein
D Spy49_0973c Putative sugar ABC transporter K23537 nupA; general nucleoside transport system ATP-binding protein
D Spy49_0212 Sugar ABC transporter, sugar-binding protein K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein
D Spy49_0213 Putative sugar transport system K02025 ABC.MS.P; multiple sugar transport system permease protein
D Spy49_0214 Sugar ABC transporter, permease protein K02026 ABC.MS.P1; multiple sugar transport system permease protein
D Spy49_0987c pstS; Phosphate ABC transporter, periplasmic phosphate-binding protein pstS K02040 pstS; phosphate transport system substrate-binding protein
D Spy49_0986 pstC; Phosphate transport system permease protein pstC K02037 pstC; phosphate transport system permease protein
D Spy49_0985c pstA; Phosphate transport system permease protein pstA K02038 pstA; phosphate transport system permease protein
D Spy49_0983c pstB; Phosphate transport ATP-binding protein pstB K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D Spy49_0984c pstB2; Phosphate transport ATP-binding protein pstB2 K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D Spy49_1040 glnP; Glutamine ABC transporter, glutamine-binding protein/permease protein K10036 glnH; glutamine transport system substrate-binding protein
D Spy49_1041 glnQ; Glutamine transport ATP-binding protein glnQ K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1]
D Spy49_0715 Putative ABC transporter K02424 tcyA; L-cystine transport system substrate-binding protein
D Spy49_0266 atmA; ABC transporter, substrate-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein
D Spy49_0716 Probable amino-acid ABC transporter permease protein yckA K10009 tcyB; L-cystine transport system permease protein
D Spy49_1287c Putative amino acid ABC transproter K10009 tcyB; L-cystine transport system permease protein
D Spy49_1286c Amino acid ABC transporter, ATP-binding protein K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1]
D Spy49_0605 Putative ABC transporter K23059 artP; arginine/lysine/histidine transporter system substrate-binding protein
D Spy49_1162c Putative amino acid ABC transporter K17077 artQ; arginine/lysine/histidine transport system permease protein
D Spy49_1161c gtr; Putative amino acid ABC transporter K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1]
D Spy49_0268 atmB; Methionine ABC transporter substrate-binding protein K02073 metQ; D-methionine transport system substrate-binding protein
D Spy49_0270 atmE; Methionine ABC transporter permease protein K02072 metI; D-methionine transport system permease protein
D Spy49_0269 atmD; Putative ABC transporter K02071 metN; D-methionine transport system ATP-binding protein
D Spy49_0797 Putative ABC transporter substrate-binding protein K01989 K01989; putative tryptophan/tyrosine transport system substrate-binding protein
D Spy49_0799 Putative ABC transport protein K05832 K05832; putative tryptophan/tyrosine transport system permease protein
D Spy49_0800 Putative ABC transporter K05833 K05833; putative tryptophan/tyrosine transport system ATP-binding protein
D Spy49_0237c Putative glutamine-binding periplasmic protein K17073 lysX1; putative lysine transport system substrate-binding protein
D Spy49_0236c Amino acid ABC transporter, ATP-binding protein K17076 lysY; putative lysine transport system ATP-binding protein
D Spy49_1011c Putative amino acid ABC transporter, periplasmic amino acid-binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D Spy49_1013c Amino acid ABC transporter, permease protein K02029 ABC.PA.P; polar amino acid transport system permease protein
D Spy49_1012c Amino acid ABC transporter, ATP-binding protein K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1]
D Spy49_0249 oppA; Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein oppA K15580 oppA; oligopeptide transport system substrate-binding protein
D Spy49_0250 oppB; Oligopeptide transport system permease protein K15581 oppB; oligopeptide transport system permease protein
D Spy49_0251 oppC; Oligopeptide transport system permease protein oppC K15582 oppC; oligopeptide transport system permease protein
D Spy49_0252 oppD; Oligopeptide transport ATP-binding protein oppD K15583 oppD; oligopeptide transport system ATP-binding protein
D Spy49_0253 oppF; Oligopeptide transport ATP-binding protein oppF K10823 oppF; oligopeptide transport system ATP-binding protein
D Spy49_1660 dppA; Dipeptide-binding ABC transporter, periplasmic substrate-binding component K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D Spy49_1661 dppB; Dipeptide transport system permease protein dppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D Spy49_1662 dppC; Dipeptide transport system permease protein dppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D Spy49_1663 dppD; Dipeptide transport ATP-binding protein dppD K02031 ddpD; peptide/nickel transport system ATP-binding protein
D Spy49_1664 dppF; Dipeptide transport ATP-binding protein dppF K02032 ddpF; peptide/nickel transport system ATP-binding protein
D Spy49_0317c fhuD; Ferrichrome-binding periplasmic protein precursor K25308 fhuD; ferric hydroxamate/heme transport system substrate-binding protein
D Spy49_0316 fhuB1; Ferrichrome transport system permease protein fhuB K25288 fhuB; ferric hydroxamate/heme transport system permease protein
D Spy49_0315 fhuG; Ferrichrome transport system permease protein fhuG K25289 fhuG; ferric hydroxamate/heme transport system permease protein
D Spy49_0318 fhuC1; Ferrichrome transport ATP-binding protein fhuC K25290 fhuA; ferric hydroxamate/heme transport system ATP-binding protein [EC:7.2.2.16]
D Spy49_1403c fhuD2; Ferrichrome-binding periplasmic protein precursor K25113 htsA; heme transport system substrate-binding protein
D Spy49_1402c fhuB2; Ferrichrome transport system permease protein fhuB K25114 htsB; heme transport system permease protein
D Spy49_1401c fhuC2; Ferrichrome transport ATP-binding protein fhuC K25115 htsC; heme transport system ATP-binding protein [EC:7.6.2.5]
D Spy49_1405c Putative Fe3+-siderophore transport protein K25120 shr; heme sequestration protein
D Spy49_1667c lmb; Laminin-binding surface protein K09815 znuA; zinc transport system substrate-binding protein
D Spy49_0549 adcA; Zinc-binding protein adcA precursor K09815 znuA; zinc transport system substrate-binding protein
D Spy49_0082 adrB; Putative ABC transporter K09816 znuB; zinc transport system permease protein
D Spy49_0081 adrC; ABC transporter K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D Spy49_0381 mtsA; Metal ABC transporter substrate-binding lipoprotein precursor K11704 mtsA; iron/zinc/manganese/copper transport system substrate-binding protein
D Spy49_0383 mtsC; Integral membrane protein MtsC, ABC transporter K11705 mtsC; iron/zinc/manganese/copper transport system permease protein
D Spy49_0382 mtsB; ATP-binding protein MtsB K11706 mtsB; iron/zinc/manganese/copper transport system ATP-binding protein
D Spy49_0183 bioY; Biotin transporter bioY K03523 bioY; biotin transport system substrate-specific component
D Spy49_1397c Permease component BL0695 of the cbiOQ-type ABC transporter K16926 htsT; energy-coupling factor transport system substrate-specific component
D Spy49_0509 Permease component SCO2325 of the cbiOQ-type ABC transporter K16927 cbrT; energy-coupling factor transport system substrate-specific component
D Spy49_1797c ABC-type cobalt transport system, permease component CbiQ K16785 ecfT; energy-coupling factor transport system permease protein
D Spy49_1396c ABC-type cobalt transport system, permease component CbiQ K16785 ecfT; energy-coupling factor transport system permease protein
D Spy49_1799c hypothetical protein K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D Spy49_1798c ABC-type cobalt transport system, ATPase component CbiO K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D Spy49_1395c ABC-type cobalt transport system, ATPase component CbiO K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D Spy49_0577 sagI; Streptolysin S export transmembrane protein (SagI) K25142 lnrN; linearmycin/streptolysin S transport system permease protein
D Spy49_0576 sagH; Streptolysin S export transmembrane protein (SagH) K25143 lnrM; linearmycin/streptolysin S transport system permease protein
D Spy49_0575 sagG; Streptolysin S export ATP-binding protein (SagG) K25144 lnrL; linearmycin/streptolysin S transport system ATP-binding protein
D Spy49_0657 Permease, putative K24948 yknZ; antimicrobial peptide resistance transport system permease protein
D Spy49_1678c Putative ABC transporter K24948 yknZ; antimicrobial peptide resistance transport system permease protein
D Spy49_1679c ABC transporter ATP-binding protein K24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-]
D Spy49_0656 Putative ABC transporter K24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-]
D Spy49_0538 ftsX; Cell division protein ftsX K09811 ftsX; cell division transport system permease protein
D Spy49_0537 ftsE; Cell division transporter, ATP-binding protein ftsE K09812 ftsE; cell division transport system ATP-binding protein
D Spy49_0438 hypothetical protein K25154 evrC; viologen exporter family transport system permease protein
D Spy49_0437 hypothetical protein K25155 evrB; viologen exporter family transport system permease protein
D Spy49_0436 tagH; Teichoic acid export ATP-binding protein tagH K25156 evrA; viologen exporter family transport system ATP-binding protein
D Spy49_1344c Putative ABC transporter K25157 ecsB; ABC-2 type transport system permease protein
D Spy49_1345c ABC transporter, ATP-binding protein K25158 ecsA; ABC-2 type transport system ATP-binding protein
D Spy49_1297c hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D Spy49_0614 rgpCc; Teichoic acid translocation permease protein tagG K01992 ABC-2.P; ABC-2 type transport system permease protein
D Spy49_1392c hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D Spy49_1021 Putative ABC transporter K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D Spy49_0615 rgpDc; Teichoic acid export ATP-binding protein tagH K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D Spy49_1298c Putative ABC transporter K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D Spy49_1393c Putative ABC transporter K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D Spy49_1578c salY; Putative ABC transporter K02004 ABC.CD.P; putative ABC transport system permease protein
D Spy49_0600 hypothetical protein K02004 ABC.CD.P; putative ABC transport system permease protein
D Spy49_0997c Putative ABC transporter, permease protein K02004 ABC.CD.P; putative ABC transport system permease protein
D Spy49_0998c Putative ABC transporter K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D Spy49_1579c salX; Putative salivaricin A ABC transporter K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D Spy49_0601 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D Spy49_0242 Iron-sulfur cluster assembly ATPase protein SufC K09013 sufC; Fe-S cluster assembly ATP-binding protein
D Spy49_0040 norM; Na+ driven multidrug efflux pump K26937 dinF; MATE family, multidrug efflux pump
D Spy49_1111c Putative oxalate:formate antiporter K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter
D Spy49_0374 glpT; Glycerol-3-phosphate transporter K02445 glpT; MFS transporter, OPA family, glycerol-3-phosphate transporter
D Spy49_0419 Putative multi-drug resistance efflux pump K08161 mdtG; MFS transporter, DHA1 family, multidrug resistance protein
D Spy49_1757c lmrP; Putative integral membrane protein K08152 lmrP; MFS transporter, DHA1 family, multidrug resistance protein B
D Spy49_0483c Putative drug resistance protein K18926 lmrB; MFS transporter, DHA2 family, lincomycin resistance protein
D Spy49_1094c ptsI; Phosphoenolpyruvate-protein phosphotransferase of PTS system K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
D Spy49_1095c ptsH; Phosphocarrier protein of PTS system K02784 ptsH; phosphocarrier protein HPr
D Spy49_1636c PTS system, glucose-specific IIBC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208]
D Spy49_1415c scrA; Putative sucrose-specific PTS permease, enzyme II K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211]
D Spy49_0485 Beta-glucoside permease IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-]
D Spy49_1737c Putative PTS system enzyme II K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201]
D Spy49_0674 fruA; PTS system, fructose-specific IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202]
D Spy49_1586c lacF; PTS system, lactose-specific IIA component (EIIA-Lac) (Lactose-permease IIA component) (Phosphotransferase enzyme II, A component) K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207]
D Spy49_1585c lacE; PTS system, lactose-specific IIBC component (EIIBC-Lac) (Lactose-permease IIBC component) (Phosphotransferase enzyme II, BC component) K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207]
D Spy49_1700c Putative PTS system, enzyme III K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D Spy49_1045c Putative PTS enzyme III K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D Spy49_1699c PTS system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]
D Spy49_1046c Putative PTS system enzyme II K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]
D Spy49_1043c Putative PTS system IIC component K02761 celB; cellobiose PTS system EIIC component
D Spy49_1698c PTS system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component
D Spy49_1329c Putative PTS system, enzyme IIA component K20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204]
D Spy49_1328c PTS system, IIB component, putative K20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204]
D Spy49_1327c Putative PTS system, enzyme IIC component K20114 gatC; galactose PTS system EIIC component
D Spy49_1354 manL; Putative mannose-specific phosphotransferase system component IIAB K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191]
D Spy49_0833 PTS system, IIA component, putative K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D Spy49_0835 Putative phosphotransferase system (PTS), enzyme II component C K02795 manY; mannose PTS system EIIC component
D Spy49_1355 manM; PTS system, mannose-specific IIC component K02795 manY; mannose PTS system EIIC component
D Spy49_0836 Putative phospotransferase system (PTS), enzyme II component D K02796 manZ; mannose PTS system EIID component
D Spy49_1356 manN; Putative mannose-specific phosphotransferase system component IID K02796 manZ; mannose PTS system EIID component
D Spy49_0834 PTS system, IIB component K19507 gfrB; fructoselysine/glucoselysine PTS system EIIB component [EC:2.7.1.-]
D Spy49_0529c agaF; Putative PTS dependent N-acetyl-galactosamine- and galactosamine IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-]
D Spy49_0527c agaV; PTS system, IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-]
D Spy49_0526c agaW; Putative PTS dependent N-acetyl-galactosamine-IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component
D Spy49_0525c agaD; Putative PTS dependent galactosamine IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component
D Spy49_1612c Putative transcriptional regulator K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]
D Spy49_0155 PTS system, IIA component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]
D Spy49_1611c PTS system, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D Spy49_0154 PTS system, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D Spy49_1610c sgaT; Transport protein SgaT, putative K03475 ulaA; ascorbate PTS system EIIC component
D Spy49_0153 Transport protein SgaT, putative K03475 ulaA; ascorbate PTS system EIIC component
D Spy49_1447c glpF2; Putative glycerol uptake facilitator protein K02440 glpF; glycerol uptake facilitator
D Spy49_1305c glpF1; Glycerol uptake facilitator protein K02440 glpF; glycerol uptake facilitator
D Spy49_0727 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D Spy49_1140c fdhC; Formate/nitrite transporter family member K21993 fdhC; formate transporter
D Spy49_0607c mscL; Putative large conductance mechanosensitive channel K03282 mscL; large conductance mechanosensitive channel
D Spy49_1564 Conserved hypothetical protein, possible mechanosensitive ion channel K22044 ybiO; moderate conductance mechanosensitive channel
D Spy49_1424 Putative divalent cation transport protein, magnesium transporter, CorA family K03284 corA; magnesium transporter
D Spy49_0311 hlyX; Putative hemolysin K03699 tlyC; magnesium and cobalt exporter, CNNM family
D Spy49_0782 Tail protein K21449 ata; trimeric autotransporter adhesin
D Spy49_0663c czcD; Putative cation-efflux system membrane protein K16264 czcD; cobalt-zinc-cadmium efflux system protein
D Spy49_1811c hypothetical protein K05340 glcU; glucose uptake protein
D Spy49_0272 Putative sodium/dicarboxylate symporter K07862 sstT; serine/threonine transporter
D Spy49_0274c Putative V-type Na+-ATPase subunit J K03498 trkH; trk/ktr system potassium uptake protein
D Spy49_0273c Potassium uptake protein, Trk family K03499 trkA; trk/ktr system potassium uptake protein
D Spy49_0651 pyrP; Putative uracil permease K02824 uraA; uracil permease
D Spy49_0888 Xanthine permease K16169 pbuX; xanthine permease
D Spy49_1351c hypothetical protein K06901 pbuG; adenine/guanine/hypoxanthine permease
D Spy49_0867 Voltage-gated chloride channel family protein K03281 clcA; chloride channel protein, CIC family
D Spy49_1100 Putative chloride channel protein K03281 clcA; chloride channel protein, CIC family
D Spy49_0557 Putative transmembrane protein K03281 clcA; chloride channel protein, CIC family
D Spy49_1316c Putative Sodium-dependent phosphate transporter K03324 yjbB; phosphate:Na+ symporter
D Spy49_1130c kup; Potassium uptake protein, putative K03549 kup; KUP system potassium uptake protein
D Spy49_0307 Riboflavin transporter YpaA K23675 fmnP; riboflavin transporter
D Spy49_0507c Thiamin transporter K16789 thiT; thiamine transporter
D Spy49_1141c hypothetical protein K16788 niaX; niacin transporter
D Spy49_0514 ftsW; Cell division protein ftsW K03588 ftsW; cell division protein FtsW
D Spy49_1671c emm49; Antiphagocytic M protein K03646 tolA; colicin import membrane protein
D Spy49_0926 Oxaloacetate decarboxylase beta chain K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
D Spy49_0933 Oxaloacetate decarboxylase beta chain K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
D Spy49_0923 Oxaloacetate decarboxylase alpha chain K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]
D Spy49_0939 oadA; Oxaloacetate decarboxylase alpha chain K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]
D Spy49_0924 hypothetical protein K01573 oadG; oxaloacetate decarboxylase (Na+ extruding) subunit gamma
D Spy49_0925 Biotin carboxyl carrier protein of oxaloacetate decarboxylase K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
D Spy49_1206c ccdA; Cytochrome c-type biogenesis protein K06196 ccdA; cytochrome c-type biogenesis protein
D Spy49_1680c Putative ATP-binding cassette transporter protein K24950 yknX; membrane fusion protein, antimicrobial resistance system
D Spy49_0655 hypothetical protein K24950 yknX; membrane fusion protein, antimicrobial resistance system
D Spy49_1050 Ribosyl nicotinamide transporter, pnuC-like protein K03811 pnuC; nicotinamide mononucleotide transporter
C 02044 Secretion system [BR:soz02044]
D Spy49_1170c YGGT family protein K02221 yggT; YggT family protein
D Spy49_1126c comE; Putative competence protein K02237 comEA; competence protein ComEA
D Spy49_1421c comEB; Putative late competence protein required for DNA binding K01493 comEB; dCMP deaminase [EC:3.5.4.12]
D Spy49_1124c comEC; DNA internalization-related competence protein ComEC/Rec2 K02238 comEC; competence protein ComEC
D Spy49_1249c Putative late competence protein required for DNA uptake K02240 comFA; competence protein ComFA
D Spy49_1248c comF; Putative late competence protein K02242 comFC; competence protein ComFC
D Spy49_0090 comYA; Putative ABC transporter subunit ComYA K02243 comGA; competence protein ComGA
D Spy49_0091 comYB; Putative competence protein, ABC transporter subunit K02244 comGB; competence protein ComGB
D Spy49_0092 comYC; Putative competence protein K02245 comGC; competence protein ComGC
D Spy49_0093 Competence protein K02246 comGD; competence protein ComGD
D Spy49_0095 comYD; Putative competence protein K02248 comGF; competence protein ComGF
D Spy49_1184 Type IV prepilin peptidase-like protein K02236 comC; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
D Spy49_1410c secA; Protein export cytoplasm protein SecA ATPase RNA helicase K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D Spy49_1704c Preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D Spy49_0421 Preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D Spy49_0068 secY; Preprotein translocase secY subunit K03076 secY; preprotein translocase subunit SecY
D Spy49_0945c ffh; Signal recognition particle, subunit Ffh SRP54 K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D Spy49_0482 ftsY; Signal recognition particle receptor protein FtsY alpha subunit K03110 ftsY; fused signal recognition particle receptor
D Spy49_1624c Preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D Spy49_0208 Membrane protein oxaA 1 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
D Spy49_0291 oxaA; Membrane protein oxaA 2 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
C 02042 Bacterial toxins [BR:soz02042]
D Spy49_0342c hypothetical protein K11044 spyA; C3 family ADP-ribosyltransferase [EC:2.4.2.-]
D Spy49_0728 Putative exfoliative toxin K11041 eta; exfoliative toxin A/B
D Spy49_0146 slo; Thiol-activated cytolysin K11031 slo; thiol-activated cytolysin
D Spy49_0311 hlyX; Putative hemolysin K03699 tlyC; magnesium and cobalt exporter, CNNM family
D Spy49_1010c cfa; CAMP factor K11045 cfa; cAMP factor
D Spy49_0568 sagA; Streptolysin S associated protein (SagA) K11046 sagA; streptolysin S associated protein
D Spy49_0910c hlyIII; Putative hemolysin III K11068 hlyIII; hemolysin III
D Spy49_0792 speH; Streptococcal pyrogenic exotoxin H (SpeH) K11040 se; staphylococcal enterotoxin
D Spy49_0187 speG; Exotoxin type G precursor K11040 se; staphylococcal enterotoxin
D Spy49_1236c hyl; Putative hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
C 02022 Two-component system [BR:soz02022]
D Spy49_0445 vicK; Two-component sensor histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
D Spy49_0444 vicR; Two-component response regulator K07668 vicR; two-component system, OmpR family, response regulator VicR
D Spy49_0979c ciaH; Putative histidine kinase protein K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
D Spy49_0980c ciaR; Transcriptional regulatory protein ciaR K14983 ciaR; two-component system, OmpR family, response regulator CiaR
D Spy49_0280 csrS; Transmembrane histidine kinase CsrS K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]
D Spy49_0279 csrR; Response regulator CsrR K18941 arlR; two-component system, OmpR family, response regulator ArlR
D Spy49_1676c Two-component system histidine kinase K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3]
D Spy49_1677c Two-component system response regulator K18987 irr; two-component system, OmpR family, response regulator Irr
D Spy49_1255c Putative two-component sensor histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
D Spy49_1254c Putative two-component response regulator K11618 liaR; two-component system, NarL family, response regulator LiaR
D Spy49_1577c salK; SalK K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK
D Spy49_1576c salR; Putative response regulator of salavaricin regulon K14989 salR; two-component system, NarL family, secretion system response regulator SalR
D Spy49_0862c Putative two-component sensor histidine kinase K02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3]
D Spy49_0861c Putative two-component response regulator K02475 K02475; two-component system, CitB family, response regulator
D Spy49_1240c Histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D Spy49_0204 fasB; Putative histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D Spy49_0205 Putative histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D Spy49_0206 fasA; Response regulator FasA K07707 agrA; two-component system, LytTR family, response regulator AgrA
D Spy49_1228c Putative two-component sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
D Spy49_1202c yesM; Putative two-component sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
D Spy49_1227c Putative two-component sensor response regulator K07720 yesN; two-component system, response regulator YesN
D Spy49_0839 Putative two-component response regulator K07720 yesN; two-component system, response regulator YesN
D Spy49_1203c yesN; Putative two-component response regulator K07720 yesN; two-component system, response regulator YesN
C 02035 Bacterial motility proteins [BR:soz02035]
D Spy49_0715 Putative ABC transporter K02424 tcyA; L-cystine transport system substrate-binding protein
D Spy49_0266 atmA; ABC transporter, substrate-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:soz04812]
D Spy49_1173c ftsZ; Cell division protein ftsZ K03531 ftsZ; cell division protein FtsZ
D Spy49_1174c ftsA; Cell division protein ftsA K03590 ftsA; cell division protein FtsA
D Spy49_1822 parB; Chromosome partitioning protein parB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
C 04147 Exosome [BR:soz04147]
D Spy49_0563 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Spy49_0234 plr; NAD-dependent glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D Spy49_1553c pgk; Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D Spy49_1017c pyk; Putatove pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D Spy49_0384c cypB; Putative cyclophilin-type protein K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D Spy49_1715c groEL; Heat shock protein 60 family chaperone GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Spy49_1374c dnaK; Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK
D Spy49_0188 pgi; Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D Spy49_1812c guaB; inosine monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D Spy49_0515 tufA; Translation elongation factor Tu K02358 tuf; elongation factor Tu
D Spy49_1346 hit; Putative cell-cycle regulation histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D Spy49_0904c ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D Spy49_0441 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D Spy49_1268 atoB; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0440 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0123 Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Spy49_0069 adk; Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D Spy49_0736 apt; Adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D Spy49_1307c glpK; Glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30]
D Spy49_1550c glnA; Glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Spy49_0025 purH; IMP cyclohydrolase/Phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D Spy49_0810 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Spy49_0516 tpi; Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D Spy49_1143c gpmA; Phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
C 02048 Prokaryotic defense system [BR:soz02048]
D Spy49_1208c hypothetical protein K15342 cas1; CRISP-associated protein Cas1
D Spy49_0825 Lipoyl-binding domain protein K15342 cas1; CRISP-associated protein Cas1
D Spy49_0826 hypothetical protein K09951 cas2; CRISPR-associated protein Cas2
D Spy49_1207c hypothetical protein K09951 cas2; CRISPR-associated protein Cas2
D Spy49_1213c ATP-dependent RNA helicase SrmB, putative K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4]
D Spy49_1209c hypothetical protein K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D Spy49_1211c Conserved hypothetical protein K19117 csd1; CRISPR-associated protein Csd1
D Spy49_1210c hypothetical protein K19118 csd2; CRISPR-associated protein Csd2
D Spy49_1212c hypothetical protein K19119 cas5d; CRISPR-associated protein Cas5d
D Spy49_0823 hypothetical protein K09952 csn1; CRISPR-associated endonuclease Csn1 [EC:3.1.-.-]
D Spy49_0827 Conserved hypothetical protein K19137 csn2; CRISPR-associated protein Csn2
D Spy49_1572 hsdR; Putative type I site-specific deoxyribonuclease K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D Spy49_1573 hsdS; Putative specificity determinant HsdS K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D Spy49_1574 hsdM; Putative type I site-specific deoxyribonuclease K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D Spy49_0097 Adenine-specific methyltransferase K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]
D Spy49_0466 hypothetical protein K07473 dinJ; DNA-damage-inducible protein J
D Spy49_0467 hypothetical protein K19092 parE1_3_4; toxin ParE1/3/4
D Spy49_1173c ftsZ; Cell division protein ftsZ K03531 ftsZ; cell division protein FtsZ
D Spy49_0721 parC; Topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D Spy49_0720 parE; Topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D Spy49_0640 nifS; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Spy49_0874c Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels [BR:soz04040]
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules [BR:soz04090]
C 01504 Antimicrobial resistance genes [BR:soz01504]
D Spy49_1378c D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
D Spy49_1037c dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
D Spy49_1036c dltB; Protein dltB K03739 dltB; membrane protein involved in D-alanine export
D Spy49_1035c dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
D Spy49_1034c dltD; Protein dltD precursor K03740 dltD; D-alanine transfer protein
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins [BR:soz00536]
D Spy49_1236c hyl; Putative hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:soz00537]
D Spy49_1236c hyl; Putative hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
D Spy49_0144 nga; Nicotine adenine dinucleotide glycohydrolase (NADGH) K18153 nga; NAD+ glycohydrolase [EC:3.2.2.5]
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:soz03100]
D Spy49_tRNAala1 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Spy49_tRNAala2 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Spy49_tRNAala3 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Spy49_tRNAala5 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Spy49_tRNAala6 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Spy49_tRNAala4 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Spy49_tRNAarg5 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Spy49_tRNAarg7 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Spy49_tRNAarg4 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Spy49_tRNAarg1 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Spy49_tRNAarg2 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Spy49_tRNAarg3 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Spy49_tRNAarg6 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Spy49_tRNAasn3 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D Spy49_tRNAasn1 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D Spy49_tRNAasn2 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D Spy49_tRNAasp1 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D Spy49_tRNAasp3 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D Spy49_tRNAasp2 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D Spy49_tRNAcys1 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D Spy49_tRNAgln1 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D Spy49_tRNAgln2 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D Spy49_tRNAglu3 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D Spy49_tRNAglu1 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D Spy49_tRNAglu2 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D Spy49_tRNAgly3 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Spy49_tRNAgly4 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Spy49_tRNAgly1 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Spy49_tRNAgly2 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Spy49_tRNAhis1 tRNA-His K14226 tRNA-His; tRNA His
D Spy49_tRNAile1 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D Spy49_tRNAile3 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D Spy49_tRNAile2 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D Spy49_tRNAleu2 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Spy49_tRNAleu4 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Spy49_tRNAleu5 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Spy49_tRNAleu7 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Spy49_tRNAleu1 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Spy49_tRNAleu3 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Spy49_tRNAleu6 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Spy49_tRNAlys1 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Spy49_tRNAlys2 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Spy49_tRNAlys3 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Spy49_tRNAmet1 tRNA-Met K14230 tRNA-Met; tRNA Met
D Spy49_tRNAmet3 tRNA-Met K14230 tRNA-Met; tRNA Met
D Spy49_tRNAmet4 tRNA-Met K14230 tRNA-Met; tRNA Met
D Spy49_tRNAmet2 tRNA-Met K14230 tRNA-Met; tRNA Met
D Spy49_tRNAphe1 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D Spy49_tRNAphe2 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D Spy49_tRNApro1 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Spy49_tRNApro2 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Spy49_tRNApseudo1 pseudogene K14233 tRNA-Ser; tRNA Ser
D Spy49_tRNApseudo3 pseudogene K14233 tRNA-Ser; tRNA Ser
D Spy49_tRNAser1 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Spy49_tRNApseudo2 pseudogene K14233 tRNA-Ser; tRNA Ser
D Spy49_tRNAthr3 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Spy49_tRNAthr1 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Spy49_tRNAthr2 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Spy49_tRNAthr4 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Spy49_tRNAtrp1 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D Spy49_tRNAtyr1 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D Spy49_tRNAtyr2 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D Spy49_tRNAval4 tRNA-Val K14237 tRNA-Val; tRNA Val
D Spy49_tRNAval3 tRNA-Val K14237 tRNA-Val; tRNA Val
D Spy49_tRNAval2 tRNA-Val K14237 tRNA-Val; tRNA Val
D Spy49_tRNAval1 tRNA-Val K14237 tRNA-Val; tRNA Val
D Spy49_rRNA16s5 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA16s6 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA16s4 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA16s2 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA16s1 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA16s3 Small Subunit Ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Spy49_rRNA23s2 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA23s4 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA23s1 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA23s5 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA23s6 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA23s3 Large Subunit Ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Spy49_rRNA5s1 5S Subunit Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_rRNA5s3 5S Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_rRNA5s2 5S Subunit Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_rRNA5s5 5S Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_rRNA5s4 5S Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_rRNA5s6 5S Ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Spy49_tmRNA tmRNA; tmRNA K15035 ssrA; transfer-messenger RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D Spy49_0530 Gluconate 5-dehydrogenase K00046 idnO; gluconate 5-dehydrogenase [EC:1.1.1.69]
D Spy49_0335 lctO; Lactate oxidase K10530 lctO; L-lactate oxidase [EC:1.1.3.2]
D Spy49_1722 nox3; Alkyl hydroperoxide reductase protein F K03387 ahpF; NADH-dependent peroxiredoxin subunit F [EC:1.8.1.-]
D Spy49_0394 mrsA; Peptide methionine sulfoxide reductase msrA K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D Spy49_1204c msrA1; Peptide methionine sulfoxide reductase msrA/msrB K12267 msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12]
D Spy49_0831 csrA; Peptide methionine sulfoxide reductase msrB K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]
D Spy49_1721 ahpC; Alkyl hydroperoxide reductase protein C K24119 ahpC; NADH-dependent peroxiredoxin subunit C [EC:1.11.1.26]
D Spy49_0668 Thioredoxin reductase K21567 fnr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1]
D Spy49_0706 arsC; Arsenate reductase K00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1]
D Spy49_1743c nrdG; Ribonucleotide reductase of class III (anaerobic), activating protein K04068 nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4]
D Spy49_0312 pflC; Pyruvate formate-lyase activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D Spy49_1703 Pyruvate formate-lyase activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D Spy49_1275c hypothetical protein K07444 ypsC; putative N6-adenine-specific DNA methylase [EC:2.1.1.-]
D Spy49_0424 Putative glutamine cyclotransferase K22757 QCT; glutaminyl-peptide cyclotransferase [EC:2.3.2.5]
D Spy49_0457 hypothetical protein K21349 ggs; glucosylglycerate synthase [EC:2.4.1.268]
D Spy49_0495 lgt; Prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]
D Spy49_0891c Putative thiamine biosynthesis lipoprotein K03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180]
D Spy49_1556c DAK2 domain protein K07030 fakA; fatty acid kinase [EC:2.7.2.18]
D Spy49_0762 DNA polymerase K02334 dpo; DNA polymerase bacteriophage-type [EC:2.7.7.7]
D Spy49_0815 Conserved hypothetical protein K18672 dacA; diadenylate cyclase [EC:2.7.7.85]
D Spy49_0494 ptsK; HPr kinase/phosphorylase K06023 hprK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-]
D Spy49_0803 estA; Tributyrin esterase K03930 estA; putative tributyrin esterase [EC:3.1.1.-]
D Spy49_0257 hypothetical protein K07015 yqeG; putative phosphatase [EC:3.1.3.-]
D Spy49_1790c DHH family protein K22927 gdpP; cyclic-di-AMP phosphodiesterase [EC:3.1.4.59]
D Spy49_0219 Sec-independent protein TatD K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D Spy49_0220 Ribonuclease M5 K05985 rnmV; ribonuclease M5 [EC:3.1.26.8]
D Spy49_1627c dexB; Glucan 1,6-alpha-glucosidase K01215 dexB; glucan 1,6-alpha-glucosidase [EC:3.2.1.70]
D Spy49_0528c ugl; Putative unsaturated glucuronyl hydrolase K18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180]
D Spy49_0247 pbp7; D-alanyl-D-alanine carboxypeptidase K01286 E3.4.16.4; D-alanyl-D-alanine carboxypeptidase [EC:3.4.16.4]
D Spy49_1630 ska; Streptokinase K14745 ska; streptokinase A [EC:3.4.-.-]
D Spy49_0684 Peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D Spy49_1615 def; Peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D Spy49_1092c Polysaccharide deacetylase family protein K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104]
D Spy49_0127 Translation initiation inhibitor K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]
D Spy49_0398 67 kDa myosin-crossreactive streptococcal antigen K10254 ohyA; oleate hydratase [EC:4.2.1.53]
D Spy49_0811c hylA; Extracellular hyaluronate lyase K01727 hysA; hyaluronate lyase [EC:4.2.2.1]
D Spy49_0522 pacL; Putative calcium-transporting ATPase K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10]
D Spy49_1146c cadA; Putative heavy metal-transporting ATPase K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]
C 99981 Carbohydrate metabolism
C 99982 Energy metabolism
D Spy49_0626c Ferredoxin K05337 fer; ferredoxin
D Spy49_0245 Iron-sulfur cluster assembly scaffold protein IscU K04488 iscU; nitrogen fixation protein NifU and related proteins
C 99983 Lipid metabolism
D Spy49_0681 DegV family protein K25232 fakB; fatty acid kinase fatty acid binding subunit
D Spy49_1150c DegV family protein K25232 fakB; fatty acid kinase fatty acid binding subunit
C 99984 Nucleotide metabolism
D Spy49_0340 nrdI.2; Ribonucleotide reduction protein NrdI K03647 nrdI; protein involved in ribonucleotide reduction
D Spy49_1634 nrdI2; Ribonucleotide reduction protein NrdI K03647 nrdI; protein involved in ribonucleotide reduction
D Spy49_1455 spd3; Streptodornase K15051 endA; DNA-entry nuclease
D Spy49_1692c mf1; Streptodornase B / Mitogenic factor 1 K15051 endA; DNA-entry nuclease
C 99985 Amino acid metabolism
D Spy49_0907 Lactoylglutathione lyase K08234 yaeR; glyoxylase I family protein
D Spy49_1172c hypothetical protein K06997 yggS; PLP dependent protein
C 99986 Glycan metabolism
C 99987 Cofactor metabolism
C 99988 Secondary metabolism
C 99999 Others
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D Spy49_1719c csp; Major cold-shock protein K03704 cspA; cold shock protein
D Spy49_1517c Putative P1-type antirepressor-phage associated K07741 antB; anti-repressor protein
D Spy49_1521c Antirepressor K07741 antB; anti-repressor protein
D Spy49_0991c Regulatory protein spx K16509 spxA; regulatory protein spx
D Spy49_1752c Conserved hypothetical protein K16509 spxA; regulatory protein spx
D Spy49_0490 hypothetical protein K06959 tex; protein Tex
C 99974 Translation
D Spy49_1252c Putative polyribonucleotide nucleotidyltransferase K07570 GSP13; general stress protein 13
C 99975 Protein processing
D Spy49_1563c tig; Cell division trigger factor tig K03545 tig; trigger factor
D Spy49_0423 smpB; SsrA-binding protein K03664 smpB; SsrA-binding protein
D Spy49_1096 nrdH; Putative glutaredoxin K06191 nrdH; glutaredoxin-like protein NrdH
D Spy49_0240 mecA; Adapter protein mecA K16511 mecA1_2; adapter protein MecA 1/2
C 99976 Replication and repair
D Spy49_0870 radC; RadC-like DNA repair protein K03630 radC; DNA repair protein RadC
D Spy49_0226 hypothetical protein K09760 rmuC; DNA recombination protein RmuC
D Spy49_1129 Conserved hypothetical protein K07461 K07461; putative endonuclease
D Spy49_0914 smf; Putative DNA processing protein K04096 smf; DNA processing protein
D Spy49_0737 dnaD; DNA replication protein DnaD, putative K02086 dnaD; DNA replication protein
D Spy49_0768 Terminase small subunit K07474 xtmA; phage terminase small subunit
D Spy49_1488c Small terminase K07474 xtmA; phage terminase small subunit
D Spy49_1487c Large terminase K06909 xtmB; phage terminase large subunit
D Spy49_0769 Terminase large subunit K06909 xtmB; phage terminase large subunit
D Spy49_1655 ATPase, AAA family K07478 ycaJ; putative ATPase
D Spy49_0763 Putative DNA primase/helicase-phage associated K06919 K06919; putative DNA primase/helicase
D Spy49_0361c Putative DNA primase-phage associated K06919 K06919; putative DNA primase/helicase
D Spy49_1819c Probable transposase for insertion-like sequence element IS1161 K07482 K07482; transposase, IS30 family
D Spy49_1056 Hypothetical t protein K07483 K07483; transposase
D Spy49_0173c hypothetical protein K07483 K07483; transposase
D Spy49_0478c Transposase OrfA, IS3 family K07483 K07483; transposase
D Spy49_1054 Conserved hypothetical protein, IS861 associated K07483 K07483; transposase
D Spy49_1060 hypothetical protein K07483 K07483; transposase
D Spy49_1101 hypothetical protein K07483 K07483; transposase
D Spy49_0346c Putative transposase, ISSmu2 K07485 K07485; transposase
D Spy49_0564c Transposase K07486 K07486; transposase
D Spy49_0408c Transposase for insertion sequence element IS905 K07493 K07493; putative transposase
D Spy49_1647c Putative transposase, IS861 K07497 K07497; putative transposase
D Spy49_0178c Putative transposase, IS861 K07497 K07497; putative transposase
D Spy49_0477c Transposase K07497 K07497; putative transposase
D Spy49_1055 Putative transposase, IS861 K07497 K07497; putative transposase
D Spy49_1057 Putative transposase, IS861 K07497 K07497; putative transposase
D Spy49_1644c Transposase K07497 K07497; putative transposase
C 99979 Viral proteins
C 99998 Others
D Spy49_1532 Conserved hypothetical protein K09747 ebfC; nucleoid-associated protein EbfC
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D Spy49_1283c aapA; Amino acid permease K03293 TC.AAT; amino acid transporter, AAT family
D Spy49_0014 Putative amino acid permease K03294 TC.APA; basic amino acid/polyamine antiporter, APA family
D Spy49_0929c Citrate transporter K03300 TC.CITMHS; citrate-Mg2+:H+ or citrate-Ca2+:H+ symporter, CitMHS family
D Spy49_1008 Putative amino acid symporter K03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family
D Spy49_0271c braB; Putative branched-chain amino acid transport protein K03311 TC.LIVCS; branched-chain amino acid:cation transporter, LIVCS family
D Spy49_1541c nupC; Nucleoside permease nupC K03317 TC.CNT; concentrative nucleoside transporter, CNT family
C 99978 Cell growth
D Spy49_1274c hypothetical protein K20073 mapZ; mid-cell-anchored protein Z
D Spy49_0209 R3H domain protein K06346 jag; spoIIIJ-associated protein
C 99993 Cell motility
C 99995 Signaling proteins
D Spy49_1179c Putative GTP-binding protein TypA/BipA K06207 typA; GTP-binding protein
D Spy49_0399 phoH; Putative phosphate starvation-induced protein K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins
C 99992 Structural proteins
D Spy49_0508c Putative endolysin, phage associated K07273 acm; lysozyme
C 99994 Others
D Spy49_0982c phoU; Putative phosphate uptake regulatory protein K02039 phoU; phosphate transport system protein
D Spy49_0332c Putative copper homeostasis protein K06201 cutC; copper homeostasis protein
B
B 09194 Poorly characterized
C 99996 General function prediction only
D Spy49_1745c Putative oxidoreductase K03810 mviM; virulence factor
D Spy49_1113c Putative transcription factor K06198 coiA; competence protein CoiA
D Spy49_0105 tRNA binding domain protein K06878 K06878; tRNA-binding protein
D Spy49_0504 hypothetical protein K07025 K07025; putative hydrolase of the HAD superfamily
D Spy49_0246 Iron-sulfur cluster assembly protein SufB K09014 sufB; Fe-S cluster assembly protein SufB
D Spy49_0243 Iron-sulfur cluster assembly protein SufD K09015 sufD; Fe-S cluster assembly protein SufD
D Spy49_1076c Ribonuclease BN K07058 K07058; membrane protein
D Spy49_0726 hypothetical protein K07146 K07146; UPF0176 protein
D Spy49_0276 lemA; Putative cytoplasmic membrane protein K03744 lemA; LemA protein
D Spy49_0491 SprT-like protein K03095 sprL; SprT-like protein
D Spy49_1784c Phage infection protein K01421 yhgE; putative membrane protein
D Spy49_1779 hypothetical protein K08974 K08974; putative membrane protein
D Spy49_0488c hypothetical protein K08986 ycgQ; putative membrane protein
D Spy49_1014c PhnA protein K06193 phnA; protein PhnA
C 99997 Function unknown
D Spy49_0520c HD domain protein K06885 K06885; uncharacterized protein
D Spy49_1560c hypothetical protein K06889 K06889; uncharacterized protein
D Spy49_0295 Membrane protein, putative K06890 K06890; uncharacterized protein
D Spy49_0164 CoA-binding domain protein K06929 K06929; uncharacterized protein
D Spy49_0294 Conserved hypothetical protein K06950 K06950; uncharacterized protein
D Spy49_0660 KH domain protein K06960 K06960; uncharacterized protein
D Spy49_1600c hypothetical protein K06962 K06962; uncharacterized protein
D Spy49_0578 Endonuclease/Exonuclease/phosphatase family protein K07004 K07004; uncharacterized protein
D Spy49_0662 hypothetical protein K07006 K07006; uncharacterized protein
D Spy49_0669 Probable regulatory protein K07035 K07035; uncharacterized protein
D Spy49_0918 Regulatory protein K07035 K07035; uncharacterized protein
D Spy49_0602c Conserved hypothetical protein K07054 K07054; uncharacterized protein
D Spy49_0489c hypothetical protein K07089 K07089; uncharacterized protein
D Spy49_0299 Conserved hypothetical protein K07095 K07095; uncharacterized protein
D Spy49_1142c Transcriptional regulator, biotin repressor family K07105 K07105; uncharacterized protein
D Spy49_0734 Putative oxidoreductase K07124 K07124; uncharacterized protein
D Spy49_0309 Conserved hypothetical protein TIGR01212 K07139 K07139; uncharacterized protein
D Spy49_0305 hypothetical protein K08998 K08998; uncharacterized protein
D Spy49_1238 hypothetical protein K09704 K09704; uncharacterized protein
D Spy49_0946c putative DNA-binding protein K09787 K09787; uncharacterized protein
D Spy49_0392 S1 RNA binding domain K00243 K00243; uncharacterized protein
D Spy49_1742 hypothetical protein K09861 K09861; uncharacterized protein
D Spy49_1048c hypothetical protein K09963 K09963; uncharacterized protein
D Spy49_0296 hypothetical protein K09976 K09976; uncharacterized protein
D Spy49_0644 Conserved hypothetical protein K07584 ysxB; uncharacterized protein
D Spy49_1243 Conserved hypothetical protein K07586 ygaC; uncharacterized protein
D Spy49_1339c Predicted nucleic-acid-binding protein K07742 ylxR; uncharacterized protein
!
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#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: May 12, 2024