+F Repair protein KO #

  DNA Repair and Recombination Proteins - Streptococcus pyogenes NZ131 (serotype M49)

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AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D Spy49_1160c phr; Putative deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E Spy49_0717 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E Spy49_1430 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E Spy49_0738 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D Long Patch-BER factors E DNA polymerase delta complex E DNA polymerase epsilon complex D Short Patch-BER factors D Other BER factors C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex E Cul4-DDB2 complex E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex E Cul4-CSA complex E Other TCR factor D TFIIH complex D RPA (replication factor A) D Other NER factors C MMR (mismatch excision repair) D Mismatch and loop recognition factors D MutL homologs D DNA polymerase delta complex D RPA (replication factor A) D RFC (replication factor C) D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex D BRCA1-core complex D BRCA1-A complex D BRCA1-B complex D BRCA1-C complex D BRCA complex D RecA family proteins D Rad52 family proteins D Rad54 family proteins D RecQ family DNA helicases D Bloom's syndrome complex (BTR) D RPA (replication factor A) D Protein phosphatase 4 D AP-5 complex D SMC5-SMC6 complex D Other HR factors C NHEJ (non-homologous end-joining) D DNA-PK complex D MRX complex D DNA Ligase 4 complex D X-family DNA polymerases D Other NHEJ factors C FA (Fanconi anemia) pathway D FA core complex D FA core complex binding factors D Bloom's syndrome complex (BTR) D FANCD2-I complex D Downstream FA components D Other FA pathway factors C Other DSBR factors D Protein phosphatase 6 D Ubiquitin ligases D Others B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group C Other TLS factors B Check point factors C Rad9-Hus1-Rad1 complex C HRAD17(Rad24)-RFC complex C Rad17-Mec3-Ddc1 complex C FPC (fork protection complex) C Triple T complex C BAG6-UBL4A-GET4 complex C Other check point factors B Other factors with a suspected DNA repair function C DNA polymerases C Nucleases C Helicases C PSO4 complex C Modulation of nucleotide pools D Spy49_1165 mutT; MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Spy49_0793 mutX; Putative 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Spy49_1640c nudB; MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Spy49_0199 dut; Putative deoxyuridine 5-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D Spy49_1160c phr; Putative deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E Spy49_0717 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E Spy49_1430 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E Spy49_1755c tag; DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] E Spy49_0416 fpg; Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E Spy49_0738 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E Spy49_0334c exoA; Putative 3-exo-deoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D RecJ E Spy49_0735 recJ; Single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D DNA ligase E Spy49_0580 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D DNA polymerase I E Spy49_0163 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] C NER (nucleotide excision repair) D GGR (global genome repair) factors E Spy49_1423c uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A E Spy49_1039c uvrB; Excinuclease ABC (Subunit B), helicase subunit of the DNA excision repair complex K03702 uvrB; excinuclease ABC subunit B E Spy49_0842 uvrC; Putative excinuclease ABC K03703 uvrC; excinuclease ABC subunit C E Spy49_1007c pcrA; Putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E Spy49_0163 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] E Spy49_0580 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) F Spy49_0087 rpoB; DNA-directed RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] F Spy49_0088 rpoC; DNA-directed RNA polymerase beta subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] F Spy49_0074 rpoA; DNA-directed RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] F Spy49_1562c rpoE; DNA-directed RNA polymerase delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta F Spy49_1263c DNA-directed RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] E TRCF (transcription-repair coupling factor) F Spy49_0006 trcF; Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] C MMR (mismatch excision repair) D Mismatch and loop recognition factors E Spy49_1759c mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS E Spy49_1434c mutS2; Putative DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2 D Molecular matchmaker E Spy49_1758c mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL D Strand discrimination factor D DNA exonucleases E Spy49_1157c xseA; Probable exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] E Spy49_1156c xseB; Probable exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D DNA polymerase III holoenzyme E Spy49_1019c dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E Spy49_1618c polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] E Spy49_0002 dnaN; Beta subunit of DNA polymerase III K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E Spy49_1123c holA; DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] E Spy49_0327 DNA polymerase III delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] E Spy49_1534c dnaQ; Putative DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E Spy49_1087c dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D DNA ligase E Spy49_0580 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Other MMR factors E Spy49_1007c pcrA; Putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E Spy49_1427c ssb2; Single-strand binding protein 2 K03111 ssb; single-strand DNA-binding protein E Spy49_1500c Single-strand binding protein 3 K03111 ssb; single-strand DNA-binding protein E Spy49_0107 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins E Spy49_1439 recD; Exodeoxyribonuclease V alpha chain K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] E Spy49_1753c recA; RecA protein K03553 recA; recombination protein RecA E Spy49_1756c ruvA; Holliday junction DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA E Spy49_0033 ruvB; Holliday junction DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E Spy49_1262c priA; Arrested fork binding K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D RecFOR pathway proteins E Spy49_1753c recA; RecA protein K03553 recA; recombination protein RecA E Spy49_0200 radA; RadA-like DNA repair protein K04485 radA; DNA repair protein RadA/Sms E Spy49_1810 recF; Recombination protein F K03629 recF; DNA replication and repair protein RecF E Spy49_1394c recG; Putative ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] E Spy49_0735 recJ; Single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] E Spy49_0017 recO; DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O) E Spy49_1138c recR; Recombination protein recR K06187 recR; recombination protein RecR E Spy49_1152c recN; Putative DNA repair and genetic recombination protein K03631 recN; DNA repair protein RecN (Recombination protein N) E Spy49_1278 recU; Recombination protein U-like protein K03700 recU; recombination protein U E Spy49_1756c ruvA; Holliday junction DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA E Spy49_0033 ruvB; Holliday junction DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D AddAB pathway proteins E Spy49_0604 rexA; Putative ATP-dependent exonuclease, subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-] E Spy49_0603 rexB; Putative ATP-dependent exonuclease, subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-] D Other HR factor E Spy49_1208c hypothetical protein K15342 cas1; CRISP-associated protein Cas1 E Spy49_0825 Lipoyl-binding domain protein K15342 cas1; CRISP-associated protein Cas1 D Archaeal homologous recombinant proteins E Spy49_0418 hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex D SHIIR (short-homology-independent illegitimate recombination) E Facilitator F Spy49_0905 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F Spy49_0560 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] F Spy49_0915 topA; Putative DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] E Supressor F Spy49_1147c DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway F Spy49_0735 recJ; Single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] F Spy49_0017 recO; DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O) F Spy49_1138c recR; Recombination protein recR K06187 recR; recombination protein RecR F Spy49_0580 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E Facilitator E Supressor F Spy49_1423c uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A F Spy49_1039c uvrB; Excinuclease ABC (Subunit B), helicase subunit of the DNA excision repair complex K03702 uvrB; excinuclease ABC subunit B B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D Spy49_1441c dinP; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] C Other SOS response factors D Spy49_1753c recA; RecA protein K03553 recA; recombination protein RecA D Spy49_0944 Putative repressor protein K01356 lexA; repressor LexA [EC:3.4.21.88] D Spy49_1152c recN; Putative DNA repair and genetic recombination protein K03631 recN; DNA repair protein RecN (Recombination protein N) D Spy49_1427c ssb2; Single-strand binding protein 2 K03111 ssb; single-strand DNA-binding protein D Spy49_1500c Single-strand binding protein 3 K03111 ssb; single-strand DNA-binding protein D Spy49_0107 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Spy49_1242 recX; Regulatory protein recX K03565 recX; regulatory protein B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases D Spy49_0541 dinG; DNA polymerase III, epsilon subunit/ATP-dependent helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] C Modulation of nucleotide pools D Spy49_1165 mutT; MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Spy49_0793 mutX; Putative 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Spy49_1640c nudB; MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Spy49_0199 dut; Putative deoxyuridine 5-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D Spy49_0341 nrdE.2; Ribonucleotide reductase of class Ib (aerobic), alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Spy49_1097 nrdE1; Ribonucleotide reductase of class Ib (aerobic), alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Spy49_0339 nrdF.2; Ribonucleotide reductase of class Ib (aerobic), beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D Spy49_1099 Ribonucleotide reductase of class Ib (aerobic), beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] C Others D Spy49_0554c hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024