+D GENES KO #

  KEGG Orthology (KO) - Streptococcus pyogenes MGAS6180 (serotype M28)

% ! A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:spb00010] D M28_Spy1196 glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] D M28_Spy0183 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D M28_Spy0961 pfk; non-allosteric 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D M28_Spy1597 fba; fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D M28_Spy0488 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D M28_Spy0227 plr; glyceraldehyde 3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D M28_Spy1591 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D M28_Spy1158 gpmA; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D M28_Spy0535 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D M28_Spy0960 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D M28_Spy0730 acoA; pyruvate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D M28_Spy0731 acoB; pyruvate dehydrogenase E1 component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D M28_Spy0732 acoC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D M28_Spy0734 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D M28_Spy0847 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D M28_Spy0039 alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D M28_Spy0040 adhA; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D M28_Spy0910 pgmA; phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D M28_Spy1112 gapN; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase K00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9] D M28_Spy0457 bglA; 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D M28_Spy1066 bglA.2; beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D M28_Spy1354 beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] C 00020 Citrate cycle (TCA cycle) [PATH:spb00020] D M28_Spy0734 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D M28_Spy0730 acoA; pyruvate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D M28_Spy0731 acoB; pyruvate dehydrogenase E1 component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D M28_Spy0732 acoC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] C 00030 Pentose phosphate pathway [PATH:spb00030] D M28_Spy0183 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D M28_Spy0218 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D M28_Spy1418 tkt; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D M28_Spy1649 transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D M28_Spy1419 transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D M28_Spy0675 rpiA; ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D M28_Spy1578 deoC; deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4] D M28_Spy0676 deoB; phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7] D M28_Spy0910 pgmA; phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D M28_Spy0821 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D M28_Spy0018 prsA; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D M28_Spy0506 kgdA; 4-hydroxy-2-oxoglutarate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] D M28_Spy1112 gapN; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase K00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9] D M28_Spy0505 2-dehydro-3-deoxygluconokinase K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45] D M28_Spy1597 fba; fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D M28_Spy0961 pfk; non-allosteric 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] C 00040 Pentose and glucuronate interconversions [PATH:spb00040] D M28_Spy1885 hasB; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D M28_Spy0437 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D M28_Spy1886 hasC; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D M28_Spy0187 hasC.2; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D M28_Spy0149 3-keto-L-gulonate-6-phosphate decarboxylase K03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85] D M28_Spy0150 L-xylulose 5-phosphate 3-epimerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22] D M28_Spy0151 araD; L-ribulose-5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4] D M28_Spy0218 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] C 00051 Fructose and mannose metabolism [PATH:spb00051] D M28_Spy1526 scrK; fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D M28_Spy1525 pmi; mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D M28_Spy0961 pfk; non-allosteric 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D M28_Spy0642 fruB; 1-phosphofructokinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56] D M28_Spy1597 fba; fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D M28_Spy0488 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D M28_Spy0643 fruA; PTS system, fructose-specific IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D M28_Spy0757 PTS system, mannose/fructose family IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D M28_Spy1468 manL; PTS system, mannose-specific IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D M28_Spy0759 ptsC; PTS system, mannose/fructose family IIC component K02795 manY; mannose PTS system EIIC component D M28_Spy1469 manM; PTS system, mannose-specific IIC component K02795 manY; mannose PTS system EIIC component D M28_Spy0760 ptsD; PTS system, mannose/fructose family IID component K02796 manZ; mannose PTS system EIID component D M28_Spy1470 manN; PTS system, mannose-specific IID component K02796 manZ; mannose PTS system EIID component C 00052 Galactose metabolism [PATH:spb00052] D M28_Spy1886 hasC; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D M28_Spy0187 hasC.2; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D M28_Spy0910 pgmA; phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D M28_Spy1196 glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] D M28_Spy1345 lacZ; beta-galactosidase K01190 lacZ; beta-galactosidase [EC:3.2.1.23] D M28_Spy1626 lacC.2; tagatose-6-phosphate kinase K00917 lacC; tagatose 6-phosphate kinase [EC:2.7.1.144] D M28_Spy0961 pfk; non-allosteric 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D M28_Spy1438 lacD.1; tagatose-bisphosphate aldolase K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40] D M28_Spy1625 lacD.2; tagatose-bisphosphate aldolase K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40] D M28_Spy1627 lacB.2; galactose-6-phosphate isomerase LacB subunit K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26] D M28_Spy1628 lacA.2; galactose-6-phosphate isomerase LacA subunit K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26] D M28_Spy1440 lacB.1; galactose-6-phosphate isomerase LacB subunit K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26] D M28_Spy1441 lacA.1; galactose-6-phosphate isomerase LacA subunit K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26] D M28_Spy1622 lacG; 6-phospho-beta-galactosidase K01220 E3.2.1.85; 6-phospho-beta-galactosidase [EC:3.2.1.85] D M28_Spy1624 lacF; PTS system, lactose-specific IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D M28_Spy1623 lacE; PTS system, lactose-specific IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D M28_Spy1530 scrB; sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D M28_Spy0502 PTS system, N-acetylgalactosamine-specific IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-] D M28_Spy0500 agaV; PTS system, N-acetylgalactosamine-specific IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-] D M28_Spy0499 PTS system, N-acetylgalactosamine-specific IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component D M28_Spy0498 agaD; PTS system, N-acetylgalactosamine-specific IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component D M28_Spy0523 agaS; galactosamine-6-phosphate deaminase (isomerizing) K02082 agaS; D-galactosamine 6-phosphate deaminase/isomerase [EC:3.5.99.-] C 00053 Ascorbate and aldarate metabolism [PATH:spb00053] D M28_Spy1885 hasB; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D M28_Spy0437 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D M28_Spy0148 PTS system, 3-keto-L-gulonate specific IIA component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D M28_Spy1652 transcription antiterminator, BglG family K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D M28_Spy0147 PTS system, 3-keto-L-gulonate specific IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D M28_Spy1651 PTS system, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D M28_Spy0146 PTS system, 3-keto-L-gulonate specific IIC component K03475 ulaA; ascorbate PTS system EIIC component D M28_Spy1650 putative transport protein sgaT K03475 ulaA; ascorbate PTS system EIIC component D M28_Spy0154 metal-dependent hydrolase K03476 ulaG; L-ascorbate 6-phosphate lactonase [EC:3.1.1.-] D M28_Spy0149 3-keto-L-gulonate-6-phosphate decarboxylase K03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85] D M28_Spy0150 L-xylulose 5-phosphate 3-epimerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22] D M28_Spy0151 araD; L-ribulose-5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4] C 00500 Starch and sucrose metabolism [PATH:spb00500] D M28_Spy1529 scrA; PTS system, sucrose-specific IIABC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D M28_Spy1530 scrB; sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D M28_Spy1886 hasC; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D M28_Spy0187 hasC.2; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D M28_Spy1733 PTS system, cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D M28_Spy1062 PTS system, cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D M28_Spy1063 PTS system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D M28_Spy1732 PTS system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D M28_Spy1731 PTS system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component D M28_Spy1060 PTS system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component D M28_Spy0457 bglA; 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D M28_Spy1066 bglA.2; beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D M28_Spy1354 beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D M28_Spy1036 glgP; glycogen phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1] D M28_Spy1047 amyB; neopullulanase K01208 cd; cyclomaltodextrinase / maltogenic alpha-amylase / neopullulanase [EC:3.2.1.54 3.2.1.133 3.2.1.135] D M28_Spy1037 malM; 4-alpha-glucanotransferase K00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25] D M28_Spy1678 PTS system, glucose-specific IIABC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208] D M28_Spy1677 exodeoxyribonuclease III K06896 mapP; maltose 6'-phosphate phosphatase [EC:3.1.3.90] D M28_Spy1046 amyA; alpha-amylase K00701 cgt; cyclomaltodextrin glucanotransferase [EC:2.4.1.19] D M28_Spy1768 PTS system, trehalose-specific IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D M28_Spy1767 dexS; trehalose-6-phosphate hydrolase K01226 treC; trehalose-6-phosphate hydrolase [EC:3.2.1.93] D M28_Spy0910 pgmA; phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D M28_Spy1196 glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] D M28_Spy0183 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D M28_Spy1526 scrK; fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:spb00520] D M28_Spy1431 nagA; N-acetylglucosamine-6-phosphate deacetylase K01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25] D M28_Spy1133 nagB; glucosamine-6-phosphate isomerase K02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6] D M28_Spy1526 scrK; fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D M28_Spy0958 glmS; isomerizing glucosamine--fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D M28_Spy0742 femD; phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10] D M28_Spy0351 gcaD; glucosamine-1-phosphate acetyltransferase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D M28_Spy0562 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D M28_Spy1099 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D M28_Spy0802 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D M28_Spy0206 N-acetylmannosamine-6-phosphate 2-epimerase K01788 nanE; N-acylglucosamine-6-phosphate 2-epimerase [EC:5.1.3.9] D M28_Spy0211 nanH; N-acetylneuraminate lyase K01639 E4.1.3.3; N-acetylneuraminate lyase [EC:4.1.3.3] D M28_Spy1196 glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] D M28_Spy0910 pgmA; phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D M28_Spy1886 hasC; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D M28_Spy0187 hasC.2; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D M28_Spy1885 hasB; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D M28_Spy0437 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D M28_Spy0757 PTS system, mannose/fructose family IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D M28_Spy1468 manL; PTS system, mannose-specific IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D M28_Spy0759 ptsC; PTS system, mannose/fructose family IIC component K02795 manY; mannose PTS system EIIC component D M28_Spy1469 manM; PTS system, mannose-specific IIC component K02795 manY; mannose PTS system EIIC component D M28_Spy0760 ptsD; PTS system, mannose/fructose family IID component K02796 manZ; mannose PTS system EIID component D M28_Spy1470 manN; PTS system, mannose-specific IID component K02796 manZ; mannose PTS system EIID component D M28_Spy0183 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D M28_Spy1525 pmi; mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] C 00620 Pyruvate metabolism [PATH:spb00620] D M28_Spy0730 acoA; pyruvate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D M28_Spy0731 acoB; pyruvate dehydrogenase E1 component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D M28_Spy0732 acoC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D M28_Spy0734 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D M28_Spy1557 pfl; formate acetyltransferase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D M28_Spy0039 alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D M28_Spy0040 adhA; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D M28_Spy0092 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D M28_Spy0826 pta; putative phosphotransacetylase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D M28_Spy0960 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D M28_Spy1473 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D M28_Spy1477 accB; biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D M28_Spy1475 accC; biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D M28_Spy1474 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D M28_Spy0287 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D M28_Spy0847 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D M28_Spy0863 ddh; D-lactate dehydrogenase K03778 ldhA; D-lactate dehydrogenase [EC:1.1.1.28] D M28_Spy0409 gloA; lactoylglutathione lyase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5] D M28_Spy0512 hydroxyacylglutathione hydrolase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D M28_Spy0810 NAD-dependent malic enzyme K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D M28_Spy0867 oadA2; oxaloacetate decarboxylase alpha chain K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] D M28_Spy0882 oadA1; oxaloacetate decarboxylase alpha chain K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] D M28_Spy0870 oxaloacetate decarboxylase beta chain K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D M28_Spy0876 oadB; oxaloacetate decarboxylase beta chain K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D M28_Spy0868 putative membrane associated protein K01573 oadG; oxaloacetate decarboxylase (Na+ extruding) subunit gamma D M28_Spy0484 ppc; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D M28_Spy0420 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy1385 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0117 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:spb00630] D M28_Spy0420 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy1385 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0117 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy1588 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D M28_Spy0841 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D M28_Spy0734 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D M28_Spy1609 glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D M28_Spy0506 kgdA; 4-hydroxy-2-oxoglutarate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] C 00640 Propanoate metabolism [PATH:spb00640] D M28_Spy0092 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D M28_Spy0826 pta; putative phosphotransacetylase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D M28_Spy0734 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D M28_Spy1557 pfl; formate acetyltransferase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D M28_Spy1473 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D M28_Spy1477 accB; biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D M28_Spy1475 accC; biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D M28_Spy1474 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D M28_Spy0847 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D M28_Spy1728 gldA; glycerol dehydrogenase K00005 gldA; glycerol dehydrogenase [EC:1.1.1.6] C 00650 Butanoate metabolism [PATH:spb00650] D M28_Spy0420 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy1385 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0117 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0118 atoD.2; acetate CoA-transferase alpha subunit AtoD K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D M28_Spy1386 atoD.1; acetate CoA-transferase alpha subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D M28_Spy1387 atoA; acetate CoA-transferase beta subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] D M28_Spy0119 atoA; acetyl-CoA:acetoacetyl-CoA transferase beta subunit AtoA K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] D M28_Spy0039 alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D M28_Spy0870 oxaloacetate decarboxylase beta chain K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D M28_Spy0876 oadB; oxaloacetate decarboxylase beta chain K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D M28_Spy0869 biotin carboxyl carrier protein of oxaloacetate decarboxylase K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma D M28_Spy0875 biotin carboxyl carrier protein of oxaloacetate decarboxylase K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma D M28_Spy0764 gabD; succinate-semialdehyde dehydrogenase [NADP+] K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D M28_Spy1557 pfl; formate acetyltransferase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D M28_Spy0667 mvaS.1; hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D M28_Spy1388 D-beta-hydroxybutyrate dehydrogenase K00019 BDH1; 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30] D M28_Spy0811 Zn-dependent alcohol dehydrogenase and related dehydrogenase K18369 adh2; alcohol dehydrogenase [EC:1.1.1.-] D M28_Spy0513 acetoin dehydrogenase K03366 butA; meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304] C 00660 C5-Branched dibasic acid metabolism C 00562 Inositol phosphate metabolism [PATH:spb00562] D M28_Spy0930 myo-inositol-1(or 4)-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D M28_Spy0349 NAD-dependent oxidoreductase K22230 iolU; scyllo-inositol 2-dehydrogenase (NADP+) [EC:1.1.1.-] D M28_Spy0488 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:spb00190] D M28_Spy0557 atpA; ATP synthase alpha chain K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D M28_Spy0559 atpD; ATPase, beta subunit K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D M28_Spy0558 atpG; ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D M28_Spy0556 atpH; ATP synthase delta chain K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D M28_Spy0560 atpC; ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D M28_Spy0554 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a D M28_Spy0555 atpF; ATP synthase B chain K02109 ATPF0B; F-type H+-transporting ATPase subunit b D M28_Spy0553 atpE; ATP synthase C chain K02110 ATPF0C; F-type H+-transporting ATPase subunit c D M28_Spy0129 ntpA; V-type sodium ATP synthase subunit A K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1] D M28_Spy0130 ntpB; V-type sodium ATP synthase subunit B K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B D M28_Spy0127 ntpC; V-type ATP synthase subunit C K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C D M28_Spy0131 ntpD; V-type sodium ATP synthase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D D M28_Spy0126 ntpE; V-type sodium ATP synthase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E D M28_Spy0128 ntpF; V-type sodium ATP synthase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F D M28_Spy0123 hypothetical protein K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H D M28_Spy0124 ntpI; V-type sodium ATP synthase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I D M28_Spy0125 ntpK; V-type sodium ATP synthase subunit K K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K D M28_Spy0308 ppaC; manganese-dependent inorganic pyrophosphatase K15986 ppaC; manganese-dependent inorganic pyrophosphatase [EC:3.6.1.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation in photosynthetic organisms C 00720 Carbon fixation pathways in prokaryotes C 00680 Methane metabolism [PATH:spb00680] D M28_Spy0841 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D M28_Spy0535 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D M28_Spy0484 ppc; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D M28_Spy1597 fba; fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D M28_Spy0961 pfk; non-allosteric 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D M28_Spy0092 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D M28_Spy0826 pta; putative phosphotransacetylase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D M28_Spy1158 gpmA; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D M28_Spy0431 hypothetical protein K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34] C 00910 Nitrogen metabolism [PATH:spb00910] D M28_Spy1588 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D M28_Spy1208 arcC; carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] D M28_Spy0195 carbonic anhydrase K01673 cynT; carbonic anhydrase [EC:4.2.1.1] C 00920 Sulfur metabolism [PATH:spb00920] D M28_Spy0525 phosphoesterase, DHH family protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] D M28_Spy1646 cysE; serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D M28_Spy1370 cysM; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis [PATH:spb00061] D M28_Spy1473 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D M28_Spy1477 accB; biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D M28_Spy1475 accC; biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D M28_Spy1474 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D M28_Spy0021 acpP.1; acyl carrier protein K02078 acpP; acyl carrier protein D M28_Spy1482 acpP.2; acyl carrier protein K02078 acpP; acyl carrier protein D M28_Spy1480 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D M28_Spy1483 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D M28_Spy1478 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D M28_Spy0348 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D M28_Spy1479 3-oxoacyl-[acyl-carrier protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D M28_Spy1476 fabZ; (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D M28_Spy1481 fabK; enoyl-[acyl-carrier protein] reductase (NADH) K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9] D M28_Spy1485 phaB; enoyl-CoA hydratase K18474 fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14] D M28_Spy0421 long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 00062 Fatty acid elongation C 00071 Fatty acid degradation [PATH:spb00071] D M28_Spy0420 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy1385 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0117 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0421 long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D M28_Spy0039 alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D M28_Spy0040 adhA; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism [PATH:spb00561] D M28_Spy1609 glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D M28_Spy1728 gldA; glycerol dehydrogenase K00005 gldA; glycerol dehydrogenase [EC:1.1.1.6] D M28_Spy1424 glpK; glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D M28_Spy0020 plsX; fatty acid/phospholipid synthesis protein K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D M28_Spy0690 putative membrane spanning protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D M28_Spy1145 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D M28_Spy0552 diacylglycerol kinase family K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107] D M28_Spy0414 1,2-diacylglycerol 3-glucosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D M28_Spy0413 glycosyltransferase K13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208] D M28_Spy0601 phosphoglycerol transferase K19005 ltaS; lipoteichoic acid synthase [EC:2.7.8.20] C 00564 Glycerophospholipid metabolism [PATH:spb00564] D M28_Spy0188 gpsA; glycerol-3-phosphate dehydrogenase [NAD(P)+] K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] D M28_Spy1423 glpO; alpha-glycerophosphate oxidase K00105 E1.1.3.21; alpha-glycerophosphate oxidase [EC:1.1.3.21] D M28_Spy0690 putative membrane spanning protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D M28_Spy1145 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D M28_Spy0552 diacylglycerol kinase family K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107] D M28_Spy0628 glycerophosphoryl diester phosphodiesterase K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] D M28_Spy1663 cdsA; phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41] D M28_Spy1879 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5] D M28_Spy1548 phosphatidylglycerophosphatase B K01096 pgpB; phosphatidylglycerophosphatase B [EC:3.1.3.27 3.6.1.75 3.1.3.4 3.6.1.27] D M28_Spy0898 cardiolipin synthetase K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism D M28_Spy1345 lacZ; beta-galactosidase K01190 lacZ; beta-galactosidase [EC:3.2.1.23] C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:spb00230] D M28_Spy0352 phosphohydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D M28_Spy0676 deoB; phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7] D M28_Spy0910 pgmA; phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D M28_Spy0821 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D M28_Spy0018 prsA; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D M28_Spy0024 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D M28_Spy0029 purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D M28_Spy0026 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D M28_Spy0023 purL; phosphoribosylformylglycinamidine synthase K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] D M28_Spy0025 purM; phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D M28_Spy0031 purK; phosphoribosylaminoimidazole carboxylase ATPase subunit K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] D M28_Spy0030 purE; phosphoribosylaminoimidazole carboxylase catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D M28_Spy0022 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D M28_Spy0033 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D M28_Spy0027 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D M28_Spy0708 apt; adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D M28_Spy0658 5'-nucleotidase K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5] D M28_Spy0678 punA; purine nucleoside phosphorylase K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1] D M28_Spy0679 deoD2; purine nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] D M28_Spy0012 hpt; hypoxanthine-guanine phosphoribosyltransferase K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] D M28_Spy1890 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D M28_Spy0293 xanthosine triphosphate pyrophosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D M28_Spy0832 xpt; xanthine phosphoribosyltransferase K03816 xpt; xanthine phosphoribosyltransferase [EC:2.4.2.22] D M28_Spy0891 guaA; glutamine-hydrolyzing GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D M28_Spy0831 guaC; GMP reductase K00364 guaC; GMP reductase [EC:1.7.1.7] D M28_Spy1382 gmk; guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8] D M28_Spy0336 nrdE.1; ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D M28_Spy1116 nrdE.2; ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D M28_Spy0334 nrdF.1; ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D M28_Spy1118 nrdF.2; ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D M28_Spy1777 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D M28_Spy1674 relA; GTP pyrophosphokinase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D M28_Spy0823 GTP pyrophosphokinase K07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5] D M28_Spy0659 GTP pyrophosphokinase K07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5] D M28_Spy0134 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D M28_Spy0064 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D M28_Spy1208 arcC; carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] C 00240 Pyrimidine metabolism [PATH:spb00240] D M28_Spy0624 carB; carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D M28_Spy0622 carA; carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D M28_Spy0621 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D M28_Spy0689 pyrC; dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3] D M28_Spy1159 pyrD; dihydroorotate dehydrogenase K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1] D M28_Spy0684 pyrE; orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D M28_Spy0683 pyrF; orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D M28_Spy0365 pyrH; uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D M28_Spy1599 pyrG; CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2] D M28_Spy0597 cmk; cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D M28_Spy1109 udk; uridine kinase K00876 udk; uridine kinase [EC:2.7.1.48] D M28_Spy0658 5'-nucleotidase K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5] D M28_Spy1580 udp; uridine phosphorylase K00757 udp; uridine phosphorylase [EC:2.4.2.3] D M28_Spy0316 upp; uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9] D M28_Spy0619 pyrR; bifunctional pyrimidine regulatory protein PyrR K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9] D M28_Spy0915 cdd; cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5] D M28_Spy1777 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D M28_Spy0336 nrdE.1; ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D M28_Spy1116 nrdE.2; ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D M28_Spy0334 nrdF.1; ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D M28_Spy1118 nrdF.2; ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D M28_Spy1535 comEB; ComE operon protein 2 K01493 comEB; dCMP deaminase [EC:3.5.4.12] D M28_Spy0319 tmk; thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D M28_Spy0193 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D M28_Spy0836 tdk2; thymidine kinase K00857 tdk; thymidine kinase [EC:2.7.1.21] D M28_Spy0668 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] D M28_Spy0827 short chain dehydrogenase K16066 ydfG; 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:spb00250] D M28_Spy1505 asnB; L-asparaginase K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D M28_Spy1207 asnA; aspartate--ammonia ligase K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1] D M28_Spy0515 aspC; aspartate aminotransferase K22457 E2.6.1.14; asparagine---oxo-acid transaminase [EC:2.6.1.14] D M28_Spy1502 aspartate aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D M28_Spy0134 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D M28_Spy0033 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D M28_Spy0621 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D M28_Spy0764 gabD; succinate-semialdehyde dehydrogenase [NADP+] K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D M28_Spy1588 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D M28_Spy0624 carB; carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D M28_Spy0622 carA; carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D M28_Spy0958 glmS; isomerizing glucosamine--fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D M28_Spy0024 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:spb00260] D M28_Spy0841 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D M28_Spy1609 glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D M28_Spy1158 gpmA; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D M28_Spy0827 short chain dehydrogenase K16066 ydfG; 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-] D M28_Spy0734 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D M28_Spy1873 sdhB; L-serine dehydratase K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] D M28_Spy1874 sdhA; L-serine dehydratase K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] C 00270 Cysteine and methionine metabolism [PATH:spb00270] D M28_Spy1646 cysE; serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D M28_Spy1370 cysM; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47] D M28_Spy0144 metB; cystathionine beta-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D M28_Spy0433 metK1; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D M28_Spy1100 metK2; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D M28_Spy0354 pfs; 5'-methylthioadenosine nucleosidase K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9] D M28_Spy1106 GAF domain-containing protein K08968 msrC; L-methionine (R)-S-oxide reductase [EC:1.8.4.14] D M28_Spy0774 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D M28_Spy1390 luxS; autoinducer-2 production protein K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21] D M28_Spy0693 bcaT; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D M28_Spy0847 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D M28_Spy1873 sdhB; L-serine dehydratase K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] D M28_Spy1874 sdhA; L-serine dehydratase K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] C 00280 Valine, leucine and isoleucine degradation [PATH:spb00280] D M28_Spy0693 bcaT; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D M28_Spy0734 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D M28_Spy0420 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy1385 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0117 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0667 mvaS.1; hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:spb00290] D M28_Spy0693 bcaT; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D M28_Spy1502 aspartate aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] C 00300 Lysine biosynthesis D M28_Spy1151 murF; UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] C 00310 Lysine degradation [PATH:spb00310] D M28_Spy0734 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D M28_Spy0420 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy1385 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0117 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0764 gabD; succinate-semialdehyde dehydrogenase [NADP+] K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D M28_Spy0118 atoD.2; acetate CoA-transferase alpha subunit AtoD K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D M28_Spy1386 atoD.1; acetate CoA-transferase alpha subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D M28_Spy1387 atoA; acetate CoA-transferase beta subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] D M28_Spy0119 atoA; acetyl-CoA:acetoacetyl-CoA transferase beta subunit AtoA K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] C 00220 Arginine biosynthesis [PATH:spb00220] D M28_Spy1211 arcB; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D M28_Spy1213 arcA; arginine deiminase K01478 arcA; arginine deiminase [EC:3.5.3.6] D M28_Spy1588 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D M28_Spy1208 arcC; carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] D M28_Spy1502 aspartate aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] C 00330 Arginine and proline metabolism [PATH:spb00330] D M28_Spy0685 amiC; amidase family protein K01426 E3.5.1.4; amidase [EC:3.5.1.4] D M28_Spy0094 proC; pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2] D M28_Spy1414 glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D M28_Spy1413 proA; gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] C 00340 Histidine metabolism [PATH:spb00340] D M28_Spy1761 hutH; histidine ammonia-lyase K01745 hutH; histidine ammonia-lyase [EC:4.3.1.3] D M28_Spy1755 hutU; urocanate hydratase K01712 hutU; urocanate hydratase [EC:4.2.1.49] D M28_Spy1754 hutI; imidazolonepropionase K01468 hutI; imidazolonepropionase [EC:3.5.2.7] D M28_Spy1762 hutG; formiminoglutamase K01479 hutG; formiminoglutamase [EC:3.5.3.8] D M28_Spy1756 glutamate formiminotransferase K00603 fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2] C 00350 Tyrosine metabolism [PATH:spb00350] D M28_Spy0039 alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D M28_Spy0040 adhA; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D M28_Spy0764 gabD; succinate-semialdehyde dehydrogenase [NADP+] K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] C 00360 Phenylalanine metabolism D M28_Spy0685 amiC; amidase family protein K01426 E3.5.1.4; amidase [EC:3.5.1.4] C 00380 Tryptophan metabolism [PATH:spb00380] D M28_Spy0734 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D M28_Spy0420 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy1385 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0117 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0685 amiC; amidase family protein K01426 E3.5.1.4; amidase [EC:3.5.1.4] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:spb00400] D M28_Spy1338 phospho-2-dehydro-3-deoxyheptonate aldolase K03856 AROA2; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D M28_Spy1339 aroB; 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4] D M28_Spy0603 aroD; 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10] D M28_Spy0429 aroE.2; shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] D M28_Spy1092 aroK; shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71] D M28_Spy1093 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D M28_Spy0604 aroF; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D M28_Spy1683 trpG; anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D M28_Spy0527 chorismate mutase K04516 AROA1; chorismate mutase [EC:5.4.99.5] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism C 00430 Taurine and hypotaurine metabolism [PATH:spb00430] D M28_Spy0826 pta; putative phosphotransacetylase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D M28_Spy0092 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:spb00450] D M28_Spy0144 metB; cystathionine beta-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D M28_Spy0239 nifS3; cysteine desulfhydrase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D M28_Spy1401 thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D M28_Spy0332 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism [PATH:spb00460] D M28_Spy1505 asnB; L-asparaginase K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D M28_Spy1207 asnA; aspartate--ammonia ligase K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1] D M28_Spy0841 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism [PATH:spb00470] D M28_Spy1522 acpS; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D M28_Spy1152 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D M28_Spy1054 dltA; D-alanine-activating enzyme K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D M28_Spy1052 D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D M28_Spy0292 glr; glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D M28_Spy1192 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] C 00480 Glutathione metabolism [PATH:spb00480] D M28_Spy0921 pepN; lysyl aminopeptidase K01256 pepN; aminopeptidase N [EC:3.4.11.2] D M28_Spy0699 glutathione S-transferase K00799 GST; glutathione S-transferase [EC:2.5.1.18] D M28_Spy0607 gor; glutathione reductase K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7] D M28_Spy0482 glutathione peroxidase K00432 gpx; glutathione peroxidase [EC:1.11.1.9] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation [PATH:spb00511] D M28_Spy1345 lacZ; beta-galactosidase K01190 lacZ; beta-galactosidase [EC:3.2.1.23] D M28_Spy1358 alpha-mannosidase K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24] C 00540 Lipopolysaccharide biosynthesis C 00542 O-Antigen repeat unit biosynthesis [PATH:spb00542] D M28_Spy0235 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:spb00541] D M28_Spy1886 hasC; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D M28_Spy0187 hasC.2; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D M28_Spy1885 hasB; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D M28_Spy0437 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D M28_Spy0714 cpsFO; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D M28_Spy0716 cpsFQ; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D M28_Spy0715 cpsFP; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D M28_Spy0581 rmlD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] D M28_Spy1525 pmi; mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D M28_Spy0351 gcaD; glucosamine-1-phosphate acetyltransferase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] C 00550 Peptidoglycan biosynthesis [PATH:spb00550] D M28_Spy0562 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D M28_Spy1099 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D M28_Spy0802 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D M28_Spy0282 murC; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D M28_Spy1192 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D M28_Spy1152 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D M28_Spy1151 murF; UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D M28_Spy0375 dgk; diacylglycerol kinase K00887 dgkA; undecaprenol kinase [EC:2.7.1.66] D M28_Spy1664 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D M28_Spy0233 bacA; putative undecaprenol kinase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D M28_Spy0303 phosphatidylglycerophosphatase B-like protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D M28_Spy1407 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D M28_Spy1191 murG; UDP-GlcNAc--MurNAc-(pentapeptide) pyrophosphoryl-undecaprenol GlcNAc transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D M28_Spy1396 pbp1A; multimodular transpeptidase-transglycosylase K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D M28_Spy1739 pbp2A; multimodular transpeptidase-transglycosylase K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] D M28_Spy0243 dacA2; D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D M28_Spy0794 dacA1; D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D M28_Spy1491 D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D M28_Spy0314 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--lysine ligase K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7] D M28_Spy0739 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K23393 murT; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13] D M28_Spy0738 putative membrane associated protein K07009 gatD; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13] D M28_Spy0892 UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10] D M28_Spy0490 murM; UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10] D M28_Spy0489 methicillin resistance expression factor K12554 murN; alanine adding enzyme [EC:2.3.2.-] D M28_Spy0080 pbp1b; multimodular transpeptidase-transglycosylase PBP 1B K03693 pbp1b; penicillin-binding protein 1B D M28_Spy1408 division specific D,D-transpeptidase K12556 pbp2X; penicillin-binding protein 2X C 00552 Teichoic acid biosynthesis [PATH:spb00552] D M28_Spy0233 bacA; putative undecaprenol kinase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D M28_Spy0303 phosphatidylglycerophosphatase B-like protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D M28_Spy0235 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D M28_Spy1054 dltA; D-alanine-activating enzyme K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D M28_Spy1052 D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D M28_Spy1053 DltB K03739 dltB; membrane protein involved in D-alanine export D M28_Spy1051 dltD; protein precursor K03740 dltD; D-alanine transfer protein D M28_Spy1463 lytR; transcriptional regulator, LytR family K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-] D M28_Spy1091 transcriptional regulator, LytR family K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-] D M28_Spy0601 phosphoglycerol transferase K19005 ltaS; lipoteichoic acid synthase [EC:2.7.8.20] D M28_Spy0414 1,2-diacylglycerol 3-glucosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis [PATH:spb00543] D M28_Spy0235 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D M28_Spy1646 cysE; serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:spb00730] D M28_Spy0610 nifS1; cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D M28_Spy0820 nifS2; cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D M28_Spy0611 thiI; thiamine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D M28_Spy0217 GTPase K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D M28_Spy0219 thiamine pyrophosphokinase K00949 thiN; thiamine pyrophosphokinase [EC:2.7.6.2] D M28_Spy0064 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] C 00740 Riboflavin metabolism [PATH:spb00740] D M28_Spy1467 hydrolase (HAD superfamily) K21064 ycsE; 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.104] D M28_Spy0933 mreA; riboflavin kinase K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] D M28_Spy0812 class B acid phosphatase K03788 aphA; acid phosphatase (class B) [EC:3.1.3.2] D M28_Spy0352 phosphohydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] C 00750 Vitamin B6 metabolism [PATH:spb00750] D M28_Spy0895 pyridoxine kinase K00868 pdxK; pyridoxine kinase [EC:2.7.1.35] D M28_Spy1605 thiD; phosphomethylpyrimidine kinase K00868 pdxK; pyridoxine kinase [EC:2.7.1.35] C 00760 Nicotinate and nicotinamide metabolism [PATH:spb00760] D M28_Spy0168 nadC; carboxylating nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D M28_Spy1399 nadE; nicotinate phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21] D M28_Spy0678 punA; purine nucleoside phosphorylase K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1] D M28_Spy0679 deoD2; purine nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] D M28_Spy0658 5'-nucleotidase K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5] D M28_Spy0255 nadD; nicotinate-nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18] D M28_Spy1398 NH(3)-dependent NAD(+) synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5] D M28_Spy0137 nga; NAD glycohydrolase K18153 nga; NAD+ glycohydrolase [EC:3.2.2.5] D M28_Spy0824 ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] D M28_Spy0764 gabD; succinate-semialdehyde dehydrogenase [NADP+] K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] C 00770 Pantothenate and CoA biosynthesis [PATH:spb00770] D M28_Spy0640 apbA; 2-dehydropantoate 2-reductase K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169] D M28_Spy0917 coaA; pantothenate kinase K00867 coaA; type I pantothenate kinase [EC:2.7.1.33] D M28_Spy0907 dpfB; phosphopantothenate--cysteine ligase K21977 coaB; phosphopantothenate---cysteine ligase (CTP) [EC:6.3.2.5] D M28_Spy0908 dfp; phosphopantothenoylcysteine decarboxylase K01598 PPCDC; phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36] D M28_Spy1205 phosphopantetheine adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D M28_Spy0397 dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24] D M28_Spy1523 alr; holo-[acyl-carrier protein] synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7] D M28_Spy0693 bcaT; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] C 00780 Biotin metabolism [PATH:spb00780] D M28_Spy1478 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D M28_Spy0348 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D M28_Spy1479 3-oxoacyl-[acyl-carrier protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D M28_Spy1476 fabZ; (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D M28_Spy1102 birA; biotin operon repressor K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism [PATH:spb00785] D M28_Spy0900 lplA; lipoate-protein ligase A K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D M28_Spy0737 lplB; lipoate-protein ligase A K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D M28_Spy0734 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D M28_Spy0730 acoA; pyruvate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D M28_Spy0731 acoB; pyruvate dehydrogenase E1 component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D M28_Spy0732 acoC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] C 00790 Folate biosynthesis [PATH:spb00790] D M28_Spy0798 folE; GTP cyclohydrolase I K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16] D M28_Spy0800 folQ; dihydroneopterin aldolase K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81] D M28_Spy0801 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D M28_Spy0799 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15] D M28_Spy0669 dyr; dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D M28_Spy0797 folC.1; folylpolyglutamate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D M28_Spy0608 folC.2; folylpolyglutamate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D M28_Spy1682 para-aminobenzoate synthetase component I K03342 pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38] C 00670 One carbon pool by folate [PATH:spb00670] D M28_Spy0669 dyr; dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D M28_Spy1758 fhs.2; formate--tetrahydrofolate ligase K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] D M28_Spy0899 fhs.1; formate--tetrahydrofolate ligase K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] D M28_Spy1173 folD; methylenetetrahydrofolate dehydrogenase (NADP+) K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D M28_Spy1757 formiminotetrahydrofolate cyclodeaminase K01500 fchA; methenyltetrahydrofolate cyclohydrolase [EC:3.5.4.9] D M28_Spy0841 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D M28_Spy0026 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D M28_Spy0027 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D M28_Spy1756 glutamate formiminotransferase K00603 fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2] D M28_Spy1379 methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D M28_Spy0668 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] C 00830 Retinol metabolism C 00860 Porphyrin metabolism C 00130 Ubiquinone and other terpenoid-quinone biosynthesis B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:spb00900] D M28_Spy0420 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy1385 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0117 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0667 mvaS.1; hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D M28_Spy0666 3-hydroxy-3-methylglutaryl-coenzyme A reductase K00054 mvaA; hydroxymethylglutaryl-CoA reductase [EC:1.1.1.88] D M28_Spy0662 mvaK1; mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36] D M28_Spy0664 mvaK2; phosphomevalonate kinase K00938 E2.7.4.2; phosphomevalonate kinase [EC:2.7.4.2] D M28_Spy0663 mvaD; diphosphomevalonate decarboxylase K01597 MVD; diphosphomevalonate decarboxylase [EC:4.1.1.33] D M28_Spy0665 isopentenyl-diphosphate delta-isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2] D M28_Spy1170 fps; dimethylallyltransferase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29] D M28_Spy1664 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation C 00907 Pinene, camphor and geraniol degradation C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D M28_Spy1418 tkt; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis [PATH:spb00523] D M28_Spy0714 cpsFO; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D M28_Spy0716 cpsFQ; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D M28_Spy0715 cpsFP; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D M28_Spy0581 rmlD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics D M28_Spy0716 cpsFQ; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis C 00332 Carbapenem biosynthesis [PATH:spb00332] D M28_Spy1414 glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D M28_Spy1413 proA; gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] C 00261 Monobactam biosynthesis C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:spb00521] D M28_Spy1196 glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] D M28_Spy0910 pgmA; phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D M28_Spy0930 myo-inositol-1(or 4)-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D M28_Spy0714 cpsFO; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D M28_Spy0716 cpsFQ; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D M28_Spy0715 cpsFP; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D M28_Spy0581 rmlD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 00524 Neomycin, kanamycin and gentamicin biosynthesis D M28_Spy1196 glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] C 00525 Acarbose and validamycin biosynthesis [PATH:spb00525] D M28_Spy0714 cpsFO; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D M28_Spy0716 cpsFQ; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] C 00401 Novobiocin biosynthesis C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis D M28_Spy1683 trpG; anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] C 00333 Prodigiosin biosynthesis D M28_Spy1480 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D M28_Spy0348 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D M28_Spy1479 3-oxoacyl-[acyl-carrier protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics D M28_Spy0021 acpP.1; acyl carrier protein K02078 acpP; acyl carrier protein D M28_Spy1482 acpP.2; acyl carrier protein K02078 acpP; acyl carrier protein C 00999 Biosynthesis of various plant secondary metabolites [PATH:spb00999] D M28_Spy0433 metK1; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D M28_Spy1100 metK2; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D M28_Spy0429 aroE.2; shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation [PATH:spb00362] D M28_Spy1771 glyoxalase family protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] D M28_Spy0835 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D M28_Spy0870 oxaloacetate decarboxylase beta chain K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D M28_Spy0876 oadB; oxaloacetate decarboxylase beta chain K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D M28_Spy0869 biotin carboxyl carrier protein of oxaloacetate decarboxylase K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma D M28_Spy0875 biotin carboxyl carrier protein of oxaloacetate decarboxylase K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma D M28_Spy0420 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy1385 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0117 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00627 Aminobenzoate degradation [PATH:spb00627] D M28_Spy0685 amiC; amidase family protein K01426 E3.5.1.4; amidase [EC:3.5.1.4] D M28_Spy0287 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D M28_Spy0118 atoD.2; acetate CoA-transferase alpha subunit AtoD K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D M28_Spy1386 atoD.1; acetate CoA-transferase alpha subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D M28_Spy1387 atoA; acetate CoA-transferase beta subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] D M28_Spy0119 atoA; acetyl-CoA:acetoacetyl-CoA transferase beta subunit AtoA K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation [PATH:spb00625] D M28_Spy0040 adhA; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D M28_Spy0039 alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] C 00361 Chlorocyclohexane and chlorobenzene degradation D M28_Spy1771 glyoxalase family protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] C 00623 Toluene degradation C 00622 Xylene degradation [PATH:spb00622] D M28_Spy1771 glyoxalase family protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] D M28_Spy0835 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00633 Nitrotoluene degradation C 00642 Ethylbenzene degradation C 00643 Styrene degradation [PATH:spb00643] D M28_Spy0685 amiC; amidase family protein K01426 E3.5.1.4; amidase [EC:3.5.1.4] D M28_Spy1771 glyoxalase family protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] C 00791 Atrazine degradation C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation D M28_Spy0835 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00626 Naphthalene degradation [PATH:spb00626] D M28_Spy0040 adhA; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D M28_Spy0039 alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:spb03020] D M28_Spy0081 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D M28_Spy0082 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D M28_Spy0069 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D M28_Spy1381 DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D M28_Spy1600 rpoE; DNA-directed RNA polymerase delta chain K03048 rpoE; DNA-directed RNA polymerase subunit delta C 03022 Basal transcription factors C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:spb03010] D M28_Spy0695 SSU ribosomal protein S1P K02945 RP-S1; small subunit ribosomal protein S1 D M28_Spy1764 rpsB; SSU ribosomal protein S2P K02967 RP-S2; small subunit ribosomal protein S2 D M28_Spy0049 rpsC; SSU ribosomal protein S3P K02982 RP-S3; small subunit ribosomal protein S3 D M28_Spy1865 rpsD; SSU ribosomal protein S4P K02986 RP-S4; small subunit ribosomal protein S4 D M28_Spy0060 rpsE; SSU ribosomal protein S5P K02988 RP-S5; small subunit ribosomal protein S5 D M28_Spy1542 rpsF; SSU ribosomal protein S6P K02990 RP-S6; small subunit ribosomal protein S6 D M28_Spy0225 rpsG; SSU ribosomal protein S7P K02992 RP-S7; small subunit ribosomal protein S7 D M28_Spy0057 rpsH; SSU ribosomal protein S8P K02994 RP-S8; small subunit ribosomal protein S8 D M28_Spy1634 rpsI; SSU ribosomal protein S9P K02996 RP-S9; small subunit ribosomal protein S9 D M28_Spy0042 rpsJ; SSU ribosomal protein S10P K02946 RP-S10; small subunit ribosomal protein S10 D M28_Spy0068 rpsK; SSU ribosomal protein S11P K02948 RP-S11; small subunit ribosomal protein S11 D M28_Spy0224 rpsL; SSU ribosomal protein S12P K02950 RP-S12; small subunit ribosomal protein S12 D M28_Spy0067 rpsM; SSU ribosomal protein S13P K02952 RP-S13; small subunit ribosomal protein S13 D M28_Spy0056 rpsN; SSU ribosomal protein S14P K02954 RP-S14; small subunit ribosomal protein S14 D M28_Spy1582 rpsN2; SSU ribosomal protein S14P K02954 RP-S14; small subunit ribosomal protein S14 D M28_Spy1654 SSU ribosomal protein S15P K02956 RP-S15; small subunit ribosomal protein S15 D M28_Spy0629 rpsP; SSU ribosomal protein S16P K02959 RP-S16; small subunit ribosomal protein S16 D M28_Spy0052 rpsQ; SSU ribosomal protein S17P K02961 RP-S17; small subunit ribosomal protein S17 D M28_Spy1540 rpsR; SSU ribosomal protein S18P K02963 RP-S18; small subunit ribosomal protein S18 D M28_Spy0047 rpsS; SSU ribosomal protein S19P K02965 RP-S19; small subunit ribosomal protein S19 D M28_Spy0918 rpsT; SSU ribosomal protein S20P K02968 RP-S20; small subunit ribosomal protein S20 D M28_Spy0576 SSU ribosomal protein S21P K02970 RP-S21; small subunit ribosomal protein S21 D M28_Spy0364 rplA; LSU ribosomal protein L1P K02863 RP-L1; large subunit ribosomal protein L1 D M28_Spy0046 rplB; LSU ribosomal protein L2P K02886 RP-L2; large subunit ribosomal protein L2 D M28_Spy0043 rplC; LSU ribosomal protein L3P K02906 RP-L3; large subunit ribosomal protein L3 D M28_Spy0044 rplD; LSU ribosomal protein L1E K02926 RP-L4; large subunit ribosomal protein L4 D M28_Spy0055 rplE; LSU ribosomal protein L5P K02931 RP-L5; large subunit ribosomal protein L5 D M28_Spy0058 rplF; LSU ribosomal protein L6P K02933 RP-L6; large subunit ribosomal protein L6 D M28_Spy0770 rplL; LSU ribosomal protein L7/L12P K02935 RP-L7; large subunit ribosomal protein L7/L12 D M28_Spy1868 rplI; LSU ribosomal protein L9P K02939 RP-L9; large subunit ribosomal protein L9 D M28_Spy0769 rplJ; LSU ribosomal protein L10P K02864 RP-L10; large subunit ribosomal protein L10 D M28_Spy0363 rplK; LSU ribosomal protein L11P K02867 RP-L11; large subunit ribosomal protein L11 D M28_Spy1635 rplM; LSU ribosomal protein L13P K02871 RP-L13; large subunit ribosomal protein L13 D M28_Spy0053 rplN; LSU ribosomal protein L14P K02874 RP-L14; large subunit ribosomal protein L14 D M28_Spy0062 rplO; LSU ribosomal protein L15P K02876 RP-L15; large subunit ribosomal protein L15 D M28_Spy0050 rplP; LSU ribosomal protein L16P K02878 RP-L16; large subunit ribosomal protein L16 D M28_Spy0070 rplQ; LSU ribosomal protein L17P K02879 RP-L17; large subunit ribosomal protein L17 D M28_Spy0059 rplR; LSU ribosomal protein L18P K02881 RP-L18; large subunit ribosomal protein L18 D M28_Spy0529 rplS; LSU ribosomal protein L19P K02884 RP-L19; large subunit ribosomal protein L19 D M28_Spy0600 rplT; LSU ribosomal protein L20P K02887 RP-L20; large subunit ribosomal protein L20 D M28_Spy0613 rplU; LSU ribosomal protein L21P K02888 RP-L21; large subunit ribosomal protein L21 D M28_Spy0048 rplV; LSU ribosomal protein L22P K02890 RP-L22; large subunit ribosomal protein L22 D M28_Spy0045 rplW; LSU ribosomal protein L23P K02892 RP-L23; large subunit ribosomal protein L23 D M28_Spy0054 rplX; LSU ribosomal protein L24P K02895 RP-L24; large subunit ribosomal protein L24 D M28_Spy0615 rpmA; LSU ribosomal protein L27P K02899 RP-L27; large subunit ribosomal protein L27 D M28_Spy1596 rpmB; LSU ribosomal protein L28P K02902 RP-L28; large subunit ribosomal protein L28 D M28_Spy0051 rpmC; LSU ribosomal protein L29P K02904 RP-L29; large subunit ribosomal protein L29 D M28_Spy0061 rpmD; LSU ribosomal protein L30P K02907 RP-L30; large subunit ribosomal protein L30 D M28_Spy0524 rpmE; LSU ribosomal protein L31P K02909 RP-L31; large subunit ribosomal protein L31 D M28_Spy1824 rpmF; LSU ribosomal protein L32P K02911 RP-L32; large subunit ribosomal protein L32 D M28_Spy1738 LSU ribosomal protein L33P K02913 RP-L33; large subunit ribosomal protein L33 D M28_Spy1825 rpmG; LSU ribosomal protein L33P K02913 RP-L33; large subunit ribosomal protein L33 D M28_Spy0400 LSU ribosomal protein L33P K02913 RP-L33; large subunit ribosomal protein L33 D M28_Spy0205 rpmH; LSU ribosomal protein L34P K02914 RP-L34; large subunit ribosomal protein L34 D M28_Spy0599 rpl36; LSU ribosomal protein L35P K02916 RP-L35; large subunit ribosomal protein L35 D M28_Spy0066 rpmJ; LSU ribosomal protein L36P K02919 RP-L36; large subunit ribosomal protein L36 D M28_SpyR0018 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0015 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0001 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0010 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0004 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0007 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0002 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0008 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0011 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0005 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0017 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0014 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0003 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_SpyR0012 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_SpyR0006 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_SpyR0009 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_SpyR0013 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_SpyR0016 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA C 00970 Aminoacyl-tRNA biosynthesis [PATH:spb00970] D M28_SpyT0001 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D M28_SpyT0011 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D M28_SpyT0029 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D M28_SpyT0042 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D M28_SpyT0057 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D M28_SpyT0062 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D M28_SpyT0048 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D M28_SpyT0067 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D M28_SpyT0045 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D M28_SpyT0009 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D M28_SpyT0019 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D M28_SpyT0060 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D M28_SpyT0044 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D M28_SpyT0065 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D M28_SpyT0061 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D M28_SpyT0043 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D M28_SpyT0003 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D M28_SpyT0013 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D M28_SpyT0055 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D M28_SpyT0064 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D M28_SpyT0047 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D M28_SpyT0040 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D M28_SpyT0033 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D M28_SpyT0066 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D M28_SpyT0050 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D M28_SpyT0026 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D M28_SpyT0031 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D M28_SpyT0007 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D M28_SpyT0017 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D M28_SpyT0039 tRNA-His K14226 tRNA-His; tRNA His D M28_SpyT0027 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D M28_SpyT0051 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D M28_SpyT0032 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D M28_SpyT0008 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D M28_SpyT0018 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D M28_SpyT0041 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D M28_SpyT0005 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D M28_SpyT0053 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D M28_SpyT0015 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D M28_SpyT0059 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D M28_SpyT0004 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D M28_SpyT0014 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D M28_SpyT0054 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D M28_SpyT0063 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D M28_SpyT0021 tRNA-Met K14230 tRNA-Met; tRNA Met D M28_SpyT0022 tRNA-Met K14230 tRNA-Met; tRNA Met D M28_SpyT0024 tRNA-Met K14230 tRNA-Met; tRNA Met D M28_SpyT0035 tRNA-Met K14230 tRNA-Met; tRNA Met D M28_SpyT0025 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D M28_SpyT0036 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D M28_SpyT0010 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D M28_SpyT0020 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D M28_SpyT0058 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D M28_SpyT0028 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D M28_SpyT0023 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D M28_SpyT0034 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D M28_SpyT0049 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D M28_SpyT0006 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D M28_SpyT0052 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D M28_SpyT0016 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D M28_SpyT0038 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D M28_SpyT0037 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D M28_SpyT0046 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D M28_SpyT0002 tRNA-Val K14237 tRNA-Val; tRNA Val D M28_SpyT0030 tRNA-Val K14237 tRNA-Val; tRNA Val D M28_SpyT0012 tRNA-Val K14237 tRNA-Val; tRNA Val D M28_SpyT0056 tRNA-Val K14237 tRNA-Val; tRNA Val D M28_Spy0197 gltX; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D M28_Spy1496 gatA; aspartyl/glutamyl-tRNA amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D M28_Spy1495 gatB; aspartyl/glutamyl-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D M28_Spy1497 gatC; glutamyl-tRNA(Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D M28_Spy1126 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D M28_Spy1822 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D M28_Spy0516 asnS; asnS K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D M28_Spy1428 glyQ; glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D M28_Spy1427 glyS; glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D M28_Spy0415 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D M28_Spy1472 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D M28_Spy1643 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D M28_Spy0332 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D M28_Spy1379 methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D M28_Spy1296 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D M28_Spy0145 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D M28_Spy1182 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D M28_Spy0474 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D M28_Spy1817 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D M28_Spy1661 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D M28_Spy1823 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D M28_Spy0566 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D M28_Spy0567 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D M28_Spy0079 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D M28_Spy1891 trsA; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:spb03060] D M28_Spy0063 secY; protein translocase subunit K03076 secY; preprotein translocase subunit SecY D M28_Spy1737 secE; protein translocase subunit K03073 secE; preprotein translocase subunit SecE D M28_Spy0401 secG; protein translocase subunit K03075 secG; preprotein translocase subunit SecG D M28_Spy1665 yajC; protein translocase subunit K03210 yajC; preprotein translocase subunit YajC D M28_Spy0202 hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D M28_Spy0286 inner membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D M28_Spy1524 secA; protein translocase subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D M28_Spy0887 ffh; signal recognition particle, subunit FFH/SRP54 K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D M28_Spy0453 ftsY; cell division protein K03110 ftsY; fused signal recognition particle receptor D M28_Spy1553 spi; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D M28_Spy0959 sipC; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D M28_Spy0108 sipA; signal peptidase I protein SipA K03100 lepB; signal peptidase I [EC:3.4.21.89] D M28_Spy0617 lsp; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:spb04122] D M28_Spy0610 nifS1; cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D M28_Spy0820 nifS2; cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D M28_Spy1872 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D M28_Spy0611 thiI; thiamine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] C 03050 Proteasome C 03018 RNA degradation [PATH:spb03018] D M28_Spy0535 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D M28_Spy1648 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D M28_Spy0402 exoribonuclease II K12573 rnr; ribonuclease R [EC:3.1.13.1] D M28_Spy1148 deaD; ATP-dependent RNA helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D M28_Spy1383 hydrolase (HAD superfamily) K18682 rny; ribonucrease Y [EC:3.1.-.-] D M28_Spy1587 Zn-dependent hydrolase K12574 rnj; ribonuclease J [EC:3.1.-.-] D M28_Spy0726 Zn-dependent hydrolase K12574 rnj; ribonuclease J [EC:3.1.-.-] D M28_Spy0961 pfk; non-allosteric 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D M28_Spy1487 dnaK; chaperone protein K04043 dnaK; molecular chaperone DnaK D M28_Spy1747 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] B B 09124 Replication and repair C 03030 DNA replication [PATH:spb03030] D M28_Spy1570 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D M28_Spy0962 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D M28_Spy1660 polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D M28_Spy1105 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D M28_Spy0320 dnaX; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D M28_Spy1140 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D M28_Spy0002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D M28_Spy1867 holB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D M28_Spy0578 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D M28_Spy0100 ssb; single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy1541 ssb2.2; phage single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy1268 ssb2.1; phage single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy0857 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D M28_Spy1552 ribonuclease HIII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4] D M28_Spy0157 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D M28_Spy0551 lig; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03410 Base excision repair [PATH:spb03410] D M28_Spy0710 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D M28_Spy0688 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D M28_Spy1544 mutY; A/G-specific adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D M28_Spy0396 fpg; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D M28_Spy1785 tag; DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D M28_Spy0327 exoA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D M28_Spy0157 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D M28_Spy0707 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D M28_Spy0551 lig; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03420 Nucleotide excision repair [PATH:spb03420] D M28_Spy0006 trcF; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D M28_Spy1537 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A D M28_Spy1056 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B D M28_Spy0765 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C D M28_Spy0949 pcrA; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D M28_Spy0157 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D M28_Spy0551 lig; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03430 Mismatch repair [PATH:spb03430] D M28_Spy1814 mutS; DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS D M28_Spy1549 mutS2; DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2 D M28_Spy1788 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL D M28_Spy0949 pcrA; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D M28_Spy1172 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D M28_Spy1171 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D M28_Spy0707 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D M28_Spy0100 ssb; single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy1541 ssb2.2; phage single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy1268 ssb2.1; phage single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy0962 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D M28_Spy1660 polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D M28_Spy0002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D M28_Spy1105 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D M28_Spy1140 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D M28_Spy0320 dnaX; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D M28_Spy1570 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D M28_Spy0551 lig; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03440 Homologous recombination [PATH:spb03440] D M28_Spy0707 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D M28_Spy0100 ssb; single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy1541 ssb2.2; phage single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy1268 ssb2.1; phage single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy1888 recF; DNA replication and repair protein recF K03629 recF; DNA replication and repair protein RecF D M28_Spy0019 recO; DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O) D M28_Spy1153 recR; recombination protein K06187 recR; recombination protein RecR D M28_Spy1783 recA; DNA recombinase RecA K03553 recA; recombination protein RecA D M28_Spy0157 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D M28_Spy1786 ruvA; holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA D M28_Spy0035 ruvB; holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D M28_Spy1509 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D M28_Spy1554 recD; exodeoxyribonuclease V alpha chain K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D M28_Spy0962 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D M28_Spy1660 polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D M28_Spy0002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D M28_Spy1105 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D M28_Spy1140 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D M28_Spy0320 dnaX; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D M28_Spy1570 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D M28_Spy1380 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] C 03450 Non-homologous end-joining C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 [PATH:spb03250] D M28_Spy0360 peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus and Lyssavirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:spb02010] D M28_Spy0763 iron(III)-binding protein K02012 afuA; iron(III) transport system substrate-binding protein D M28_Spy0806 spermidine/putrescine-binding protein K11069 potD; spermidine/putrescine transport system substrate-binding protein D M28_Spy0805 potC; spermidine/putrescine transport system permease protein K11070 potC; spermidine/putrescine transport system permease protein D M28_Spy0804 potB; spermidine/putrescine transport system permease protein K11071 potB; spermidine/putrescine transport system permease protein D M28_Spy0803 potA; spermidine/putrescine transport ATP-binding protein K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11] D M28_Spy0156 opuABC; glycine betaine-binding protein K02001 proW; glycine betaine/proline transport system permease protein D M28_Spy0155 opuAA; glycine betaine transport ATP-binding protein K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9] D M28_Spy0830 glycine betaine transport system permease protein K05845 opuC; osmoprotectant transport system substrate-binding protein D M28_Spy0829 proV; glycine betaine transport ATP-binding protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9] D M28_Spy1670 msmK; multiple sugar transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D M28_Spy1048 malX; maltose/maltodextrin-binding protein K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein D M28_Spy1039 malE; maltose/maltodextrin-binding protein K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein D M28_Spy1040 malF; maltose transport system permease protein K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D M28_Spy1045 malC; maltose transport system permease protein K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D M28_Spy1041 malG; maltose transport system permease protein K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D M28_Spy1044 malD; maltodextrin transport system permease protein K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D M28_Spy1349 sugar-binding protein K17318 lplA; putative aldouronate transport system substrate-binding protein D M28_Spy1351 sugar transport system permease protein K17319 lplB; putative aldouronate transport system permease protein D M28_Spy1350 sugar transport system permease protein K17320 lplC; putative aldouronate transport system permease protein D M28_Spy0914 nucleoside-binding protein K07335 bmpA; basic membrane protein A and related proteins D M28_Spy0135 nucleoside-binding protein K07335 bmpA; basic membrane protein A and related proteins D M28_Spy0912 nucleoside transport system permease protein K23535 nupB; general nucleoside transport system permease protein D M28_Spy0911 nucleoside transport system permease protein K23536 nupC; general nucleoside transport system permease protein D M28_Spy0913 nucleoside transport ATP-binding protein K23537 nupA; general nucleoside transport system ATP-binding protein D M28_Spy0928 pstS; phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D M28_Spy0927 pstC; phosphate transport system permease protein K02037 pstC; phosphate transport system permease protein D M28_Spy0926 pstA; phosphate transport system permease protein K02038 pstA; phosphate transport system permease protein D M28_Spy0924 pstB; phosphate transport ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D M28_Spy0925 pstB2; phosphate transport ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D M28_Spy1057 glnH; transporter K10036 glnH; glutamine transport system substrate-binding protein D M28_Spy1058 glnQ.2; glutamine transport ATP-binding protein K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1] D M28_Spy0686 cystine-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D M28_Spy0262 ABC transporter substrate-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D M28_Spy0687 cystine transport system permease protein K10009 tcyB; L-cystine transport system permease protein D M28_Spy1404 amino acid ABC transporter permease protein K10009 tcyB; L-cystine transport system permease protein D M28_Spy1403 transporter K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1] D M28_Spy0575 arginine-binding protein K23059 artP; arginine/lysine/histidine transporter system substrate-binding protein D M28_Spy1177 artQ; arginine transport system permease protein K17077 artQ; arginine/lysine/histidine transport system permease protein D M28_Spy1176 artP; arginine transport ATP-binding protein K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1] D M28_Spy0230 ABC transporter amino acid-binding protein K17073 lysX1; putative lysine transport system substrate-binding protein D M28_Spy0229 amino acid transport ATP-binding protein K17076 lysY; putative lysine transport system ATP-binding protein D M28_Spy0263 ABC transporter substrate-binding protein K02073 metQ; D-methionine transport system substrate-binding protein D M28_Spy0265 ABC transporter permease protein K02072 metI; D-methionine transport system permease protein D M28_Spy0264 ABC transporter ATP-binding protein K02071 metN; D-methionine transport system ATP-binding protein D M28_Spy0244 oppA; oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein D M28_Spy0245 oppB; oligopeptide transport system permease protein K15581 oppB; oligopeptide transport system permease protein D M28_Spy0246 oppC; oligopeptide transport system permease protein K15582 oppC; oligopeptide transport system permease protein D M28_Spy0247 oppD; oligopeptide transport ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein D M28_Spy0248 oppF; oligopeptide transport ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein D M28_Spy0521 high-affinity zinc uptake system protein ZnuA precursor K09815 znuA; zinc transport system substrate-binding protein D M28_Spy1696 lmb; laminin binding protein K09815 znuA; zinc transport system substrate-binding protein D M28_Spy0077 adcB; high-affinity zinc uptake system membrane protein K09816 znuB; zinc transport system permease protein D M28_Spy0076 adcC; high-affinity zinc uptake system ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D M28_Spy0357 mtsA; manganese-binding protein K11704 mtsA; iron/zinc/manganese/copper transport system substrate-binding protein D M28_Spy0359 mtsC; manganese transport system membrane protein K11705 mtsC; iron/zinc/manganese/copper transport system permease protein D M28_Spy0358 mtsB; manganese transport system ATP-binding protein K11706 mtsB; iron/zinc/manganese/copper transport system ATP-binding protein D M28_Spy0175 BioY K03523 bioY; biotin transport system substrate-specific component D M28_Spy1876 cbiQ; cobalt transport protein K16785 ecfT; energy-coupling factor transport system permease protein D M28_Spy1512 cobalt transport protein cbiQ K16785 ecfT; energy-coupling factor transport system permease protein D M28_Spy1878 cbiO1; cobalt transport ATP-binding protein K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D M28_Spy1877 cbiO2; cobalt transport ATP-binding protein K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D M28_Spy0786 srtE; lantibiotic transport permease protein K20491 nisE; lantibiotic transport system permease protein D M28_Spy0787 srtG; lantibiotic transport permease protein K20492 nisG; lantibiotic transport system permease protein D M28_Spy0785 srtF; lantibiotic transport ATP-binding protein K20490 nisF; lantibiotic transport system ATP-binding protein D M28_Spy0511 ftsX; cell division protein K09811 ftsX; cell division transport system permease protein D M28_Spy0510 ftsE; cell division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein D M28_Spy0190 ABC transporter ATP-binding and permease protein K18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump D M28_Spy0191 ABC transporter ATP-binding and permease protein K18892 patB; ATP-binding cassette, subfamily B, multidrug efflux pump D M28_Spy0844 multidrug resistance ABC transporter ATP-binding and permease protein K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump D M28_Spy0845 multidrug resistance ABC transporter ATP-binding and permease protein K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump C 02060 Phosphotransferase system (PTS) [PATH:spb02060] D M28_Spy1113 pstI; phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] D M28_Spy1114 ptsH; phosphocarrier protein HPr K02784 ptsH; phosphocarrier protein HPr D M28_Spy1678 PTS system, glucose-specific IIABC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208] D M28_Spy1529 scrA; PTS system, sucrose-specific IIABC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D M28_Spy0456 PTS system, beta-glucoside-specific IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D M28_Spy1768 PTS system, trehalose-specific IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D M28_Spy1624 lacF; PTS system, lactose-specific IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D M28_Spy1623 lacE; PTS system, lactose-specific IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D M28_Spy1733 PTS system, cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D M28_Spy1062 PTS system, cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D M28_Spy1063 PTS system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D M28_Spy1732 PTS system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D M28_Spy1731 PTS system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component D M28_Spy1060 PTS system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component D M28_Spy0757 PTS system, mannose/fructose family IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D M28_Spy1468 manL; PTS system, mannose-specific IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D M28_Spy0759 ptsC; PTS system, mannose/fructose family IIC component K02795 manY; mannose PTS system EIIC component D M28_Spy1469 manM; PTS system, mannose-specific IIC component K02795 manY; mannose PTS system EIIC component D M28_Spy0760 ptsD; PTS system, mannose/fructose family IID component K02796 manZ; mannose PTS system EIID component D M28_Spy1470 manN; PTS system, mannose-specific IID component K02796 manZ; mannose PTS system EIID component D M28_Spy0758 ptsB; PTS system, mannose/fructose family IIB component K19507 gfrB; fructoselysine/glucoselysine PTS system EIIB component [EC:2.7.1.-] D M28_Spy0502 PTS system, N-acetylgalactosamine-specific IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-] D M28_Spy0500 agaV; PTS system, N-acetylgalactosamine-specific IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-] D M28_Spy0499 PTS system, N-acetylgalactosamine-specific IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component D M28_Spy0498 agaD; PTS system, N-acetylgalactosamine-specific IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component D M28_Spy1444 PTS system, galactose-specific IIA component K20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204] D M28_Spy1443 PTS system, galactose-specific IIB component K20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204] D M28_Spy1442 PTS system, galactose-specific IIC component K20114 gatC; galactose PTS system EIIC component D M28_Spy0148 PTS system, 3-keto-L-gulonate specific IIA component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D M28_Spy1652 transcription antiterminator, BglG family K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D M28_Spy0147 PTS system, 3-keto-L-gulonate specific IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D M28_Spy1651 PTS system, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D M28_Spy0146 PTS system, 3-keto-L-gulonate specific IIC component K03475 ulaA; ascorbate PTS system EIIC component D M28_Spy1650 putative transport protein sgaT K03475 ulaA; ascorbate PTS system EIIC component D M28_Spy0643 fruA; PTS system, fructose-specific IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D M28_Spy0642 fruB; 1-phosphofructokinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56] C 03070 Bacterial secretion system [PATH:spb03070] D M28_Spy1737 secE; protein translocase subunit K03073 secE; preprotein translocase subunit SecE D M28_Spy0401 secG; protein translocase subunit K03075 secG; preprotein translocase subunit SecG D M28_Spy0063 secY; protein translocase subunit K03076 secY; preprotein translocase subunit SecY D M28_Spy1665 yajC; protein translocase subunit K03210 yajC; preprotein translocase subunit YajC D M28_Spy0202 hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D M28_Spy0286 inner membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D M28_Spy1524 secA; protein translocase subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D M28_Spy0453 ftsY; cell division protein K03110 ftsY; fused signal recognition particle receptor D M28_Spy0887 ffh; signal recognition particle, subunit FFH/SRP54 K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] B B 09132 Signal transduction C 02020 Two-component system [PATH:spb02020] D M28_Spy0928 pstS; phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D M28_Spy1898 htrA; protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D M28_Spy0424 vicK; two-component sensor histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] D M28_Spy0423 vicR; two-component response regulator K07668 vicR; two-component system, OmpR family, response regulator VicR D M28_Spy0001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein D M28_Spy1054 dltA; D-alanine-activating enzyme K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D M28_Spy1053 DltB K03739 dltB; membrane protein involved in D-alanine export D M28_Spy1052 D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D M28_Spy1051 dltD; protein precursor K03740 dltD; D-alanine transfer protein D M28_Spy0919 ciaH; sensor protein K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3] D M28_Spy0920 ciaR; transcriptional regulatory protein K14983 ciaR; two-component system, OmpR family, response regulator CiaR D M28_Spy1491 D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D M28_Spy0275 covS; CsrS K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3] D M28_Spy0274 covR; TCS DNA-binding response regulator, control of virulence CovR K18941 arlR; two-component system, OmpR family, response regulator ArlR D M28_Spy1708 ihk; two component system histidine kinase K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3] D M28_Spy1709 irr; two-component response regulator K18987 irr; two-component system, OmpR family, response regulator Irr D M28_Spy0780 srtK; sensor protein K20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3] D M28_Spy0779 srtR; two-component response regulator K20488 nisR; two-component system, OmpR family, lantibiotic biosynthesis response regulator NisR/SpaR D M28_Spy0781 srtA; lantibiotic K20482 nisA; lantibiotic bacteriocin D M28_Spy0784 serine (threonine) dehydratase K20483 nisB; lantibiotic biosynthesis protein D M28_Spy0783 lanthionine synthetase K20484 nisC; lantibiotic biosynthesis protein D M28_Spy0782 srtT; ABC transporter (ATP binding)-lantibiotic associated K20485 nisT; ATP-binding cassette, subfamily B, bacterial NisT/SpaT D M28_Spy0785 srtF; lantibiotic transport ATP-binding protein K20490 nisF; lantibiotic transport system ATP-binding protein D M28_Spy0786 srtE; lantibiotic transport permease protein K20491 nisE; lantibiotic transport system permease protein D M28_Spy0787 srtG; lantibiotic transport permease protein K20492 nisG; lantibiotic transport system permease protein D M28_Spy0883 citC; [citrate [pro-3S]-lyase] ligase K01910 citC; [citrate (pro-3S)-lyase] ligase [EC:6.2.1.22] D M28_Spy0878 citD; citrate lyase acyl carrier protein K01646 citD; citrate lyase subunit gamma (acyl carrier protein) D M28_Spy0879 citE; citrate lyase beta chain K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34] D M28_Spy0880 citF; citrate lyase alpha chain K01643 citF; citrate lyase subunit alpha / citrate CoA-transferase [EC:2.8.3.10] D M28_Spy0881 citX; apo-citrate lyase phosphoribosyl-dephospho-CoA transferase K05964 citX; holo-ACP synthase [EC:2.7.7.61] D M28_Spy0871 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52] D M28_Spy0810 NAD-dependent malic enzyme K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D M28_Spy0809 malP; malate-sodium symport K11616 maeN; malate:Na+ symporter D M28_Spy1359 rocA; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D M28_Spy0198 fasB; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D M28_Spy0199 fasC; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D M28_Spy0200 fasA; response regulator K07707 agrA; two-component system, LytTR family, response regulator AgrA D M28_Spy0251 comX; competence-specific sigma factor ComX K12296 comX1_2; competence protein ComX D M28_Spy1607 comX.2; competence-specific sigma factor K12296 comX1_2; competence protein ComX D M28_Spy0010 hypothetical protein K01467 ampC; beta-lactamase class C [EC:3.5.2.6] D M28_Spy1374 yvqE; two-component sensor protein K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3] D M28_Spy1373 yvqC; two-component response regulator K11618 liaR; two-component system, NarL family, response regulator LiaR D M28_Spy1616 sensory transduction protein kinase K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK D M28_Spy1615 salR; transcriptional regulatory protein K14989 salR; two-component system, NarL family, secretion system response regulator SalR D M28_Spy1588 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D M28_Spy0118 atoD.2; acetate CoA-transferase alpha subunit AtoD K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D M28_Spy1386 atoD.1; acetate CoA-transferase alpha subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D M28_Spy1387 atoA; acetate CoA-transferase beta subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] D M28_Spy0119 atoA; acetyl-CoA:acetoacetyl-CoA transferase beta subunit AtoA K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] D M28_Spy0115 atoE; short-chain fatty acids transporter K02106 atoE; short-chain fatty acids transporter D M28_Spy0420 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy1385 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0117 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy1218 yesM; two-component system sensor kinase YesM K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D M28_Spy1347 two-component sensor kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D M28_Spy1346 two-component response regulator K07720 yesN; two-component system, response regulator YesN D M28_Spy0762 two-component response regulator K07720 yesN; two-component system, response regulator YesN D M28_Spy1219 yesN; two-component system response regulator YesN K07720 yesN; two-component system, response regulator YesN D M28_Spy0036 protein tyrosine phosphatase K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:spb02024] D M28_Spy1390 luxS; autoinducer-2 production protein K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21] D M28_Spy1683 trpG; anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D M28_Spy0421 long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D M28_Spy1359 rocA; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D M28_Spy0198 fasB; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D M28_Spy0199 fasC; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D M28_Spy0200 fasA; response regulator K07707 agrA; two-component system, LytTR family, response regulator AgrA D M28_Spy0139 slo; streptolysin O K11031 slo; thiol-activated cytolysin D M28_Spy0919 ciaH; sensor protein K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3] D M28_Spy0920 ciaR; transcriptional regulatory protein K14983 ciaR; two-component system, OmpR family, response regulator CiaR D M28_Spy0244 oppA; oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein D M28_Spy0245 oppB; oligopeptide transport system permease protein K15581 oppB; oligopeptide transport system permease protein D M28_Spy0246 oppC; oligopeptide transport system permease protein K15582 oppC; oligopeptide transport system permease protein D M28_Spy0247 oppD; oligopeptide transport ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein D M28_Spy0248 oppF; oligopeptide transport ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein D M28_Spy0034 comR; competence transcriptional regulator ComR K20342 comR; HTH-type transcriptional regulator, regulator for ComX D M28_Spy0251 comX; competence-specific sigma factor ComX K12296 comX1_2; competence protein ComX D M28_Spy1607 comX.2; competence-specific sigma factor K12296 comX1_2; competence protein ComX D M28_Spy0395 mutR; transcriptional regulator K20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator D M28_Spy0428 transcriptional regulator K20374 rgg3; HTH-type transcriptional regulator, SHP3-responsive repressor D M28_Spy1689 dppA; dipeptide-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D M28_Spy1690 dppB; dipeptide transport system permease protein K02033 ABC.PE.P; peptide/nickel transport system permease protein D M28_Spy1691 dppC; dipeptide transport system permease protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein D M28_Spy1692 dppD; dipeptide transport ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D M28_Spy1693 dppE; dipeptide transport ATP-binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein D M28_Spy1724 rgg; transcriptional regulator K20375 ropB; HTH-type transcriptional regulator, pheromone-responsive regulator D M28_Spy1721 speB; pyrogenic exotoxin B K01364 speB; streptopain [EC:3.4.22.10] D M28_Spy1438 lacD.1; tagatose-bisphosphate aldolase K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40] D M28_Spy1625 lacD.2; tagatose-bisphosphate aldolase K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40] D M28_Spy0202 hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D M28_Spy0286 inner membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D M28_Spy1737 secE; protein translocase subunit K03073 secE; preprotein translocase subunit SecE D M28_Spy0401 secG; protein translocase subunit K03075 secG; preprotein translocase subunit SecG D M28_Spy0063 secY; protein translocase subunit K03076 secY; preprotein translocase subunit SecY D M28_Spy1665 yajC; protein translocase subunit K03210 yajC; preprotein translocase subunit YajC D M28_Spy1524 secA; protein translocase subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D M28_Spy0453 ftsY; cell division protein K03110 ftsY; fused signal recognition particle receptor D M28_Spy0887 ffh; signal recognition particle, subunit FFH/SRP54 K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D M28_Spy0781 srtA; lantibiotic K20482 nisA; lantibiotic bacteriocin D M28_Spy0784 serine (threonine) dehydratase K20483 nisB; lantibiotic biosynthesis protein D M28_Spy0783 lanthionine synthetase K20484 nisC; lantibiotic biosynthesis protein D M28_Spy0782 srtT; ABC transporter (ATP binding)-lantibiotic associated K20485 nisT; ATP-binding cassette, subfamily B, bacterial NisT/SpaT D M28_Spy0780 srtK; sensor protein K20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3] D M28_Spy0779 srtR; two-component response regulator K20488 nisR; two-component system, OmpR family, lantibiotic biosynthesis response regulator NisR/SpaR D M28_Spy0785 srtF; lantibiotic transport ATP-binding protein K20490 nisF; lantibiotic transport system ATP-binding protein D M28_Spy0786 srtE; lantibiotic transport permease protein K20491 nisE; lantibiotic transport system permease protein D M28_Spy0787 srtG; lantibiotic transport permease protein K20492 nisG; lantibiotic transport system permease protein C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis C 02040 Flagellar assembly [PATH:spb02040] D M28_Spy0686 cystine-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D M28_Spy0262 ABC transporter substrate-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D M28_Spy0579 rpoD; RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D M28_Spy0535 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells D M28_Spy0105 sfb1; fibronectin binding protein 1 K13734 sfb1; fibronectin-binding protein 1 D M28_Spy0107 cpa; collagen-binding protein Cpa, pilus ancillary protein 1 K13734 sfb1; fibronectin-binding protein 1 D M28_Spy1715 sfbX; fibronectin-binding protein K13734 sfb1; fibronectin-binding protein 1 B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance [PATH:spb01501] D M28_Spy0010 hypothetical protein K01467 ampC; beta-lactamase class C [EC:3.5.2.6] D M28_Spy0244 oppA; oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein D M28_Spy0245 oppB; oligopeptide transport system permease protein K15581 oppB; oligopeptide transport system permease protein D M28_Spy0246 oppC; oligopeptide transport system permease protein K15582 oppC; oligopeptide transport system permease protein D M28_Spy0247 oppD; oligopeptide transport ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein D M28_Spy0248 oppF; oligopeptide transport ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein D M28_Spy1396 pbp1A; multimodular transpeptidase-transglycosylase K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D M28_Spy0080 pbp1b; multimodular transpeptidase-transglycosylase PBP 1B K03693 pbp1b; penicillin-binding protein 1B D M28_Spy1739 pbp2A; multimodular transpeptidase-transglycosylase K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] D M28_Spy1408 division specific D,D-transpeptidase K12556 pbp2X; penicillin-binding protein 2X C 01502 Vancomycin resistance [PATH:spb01502] D M28_Spy1152 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D M28_Spy1522 acpS; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D M28_Spy1151 murF; UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D M28_Spy1407 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D M28_Spy1191 murG; UDP-GlcNAc--MurNAc-(pentapeptide) pyrophosphoryl-undecaprenol GlcNAc transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D M28_Spy1491 D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:spb01503] D M28_Spy1898 htrA; protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D M28_Spy0360 peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D M28_Spy1054 dltA; D-alanine-activating enzyme K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D M28_Spy1053 DltB K03739 dltB; membrane protein involved in D-alanine export D M28_Spy1052 D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D M28_Spy1051 dltD; protein precursor K03740 dltD; D-alanine transfer protein D M28_Spy1721 speB; pyrogenic exotoxin B K01364 speB; streptopain [EC:3.4.22.10] B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:spb01000] C 01001 Protein kinases [BR:spb01001] D M28_Spy1376 serine/threonine protein kinase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] D M28_Spy0424 vicK; two-component sensor histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] D M28_Spy0919 ciaH; sensor protein K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3] D M28_Spy0275 covS; CsrS K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3] D M28_Spy1708 ihk; two component system histidine kinase K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3] D M28_Spy0780 srtK; sensor protein K20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3] D M28_Spy1374 yvqE; two-component sensor protein K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3] D M28_Spy1616 sensory transduction protein kinase K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK D M28_Spy0808 dpiB; sensor kinase K02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3] D M28_Spy1359 rocA; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D M28_Spy0198 fasB; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D M28_Spy0199 fasC; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D M28_Spy1218 yesM; two-component system sensor kinase YesM K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D M28_Spy1347 two-component sensor kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C 01009 Protein phosphatases and associated proteins [BR:spb01009] D M28_Spy0961 pfk; non-allosteric 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D M28_Spy1377 pppL; protein phosphatase 2C K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16] C 01002 Peptidases and inhibitors [BR:spb01002] D M28_Spy0617 lsp; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] D M28_Spy1397 pepC; aminopeptidase C K01372 BLMH; bleomycin hydrolase [EC:3.4.22.40] D M28_Spy1721 speB; pyrogenic exotoxin B K01364 speB; streptopain [EC:3.4.22.10] D M28_Spy0405 pcp; pyrrolidone-carboxylate peptidase K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3] D M28_Spy0891 guaA; glutamine-hydrolyzing GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D M28_Spy0817 glutamine amidotransferase, class I K07010 K07010; putative glutamine amidotransferase D M28_Spy0017 sibA; secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] D M28_Spy1703 mrp; emm related protein Mrp K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] D M28_Spy0024 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D M28_Spy0958 glmS; isomerizing glucosamine--fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D M28_Spy0106 srtC; class C sortase protein SrtC K07284 srtA; sortase A [EC:3.4.22.70] D M28_Spy0849 sortase K07284 srtA; sortase A [EC:3.4.22.70] D M28_Spy0110 srtB; class B sortase protein SrtB K08600 srtB; sortase B [EC:3.4.22.71] D M28_Spy0520 pepD; dipeptidase K08659 pepDA; dipeptidase [EC:3.4.-.-] D M28_Spy1123 CaaX amino terminal protease family K07052 K07052; CAAX protease family protein D M28_Spy0544 sagE; streptolysin S putative self-immunity protein K07052 K07052; CAAX protease family protein D M28_Spy0921 pepN; lysyl aminopeptidase K01256 pepN; aminopeptidase N [EC:3.4.11.2] D M28_Spy1130 pepB; oligoendopeptidase F K08602 pepF; oligoendopeptidase F [EC:3.4.24.-] D M28_Spy1766 pepO; neutral endopeptidase K07386 pepO; putative endopeptidase [EC:3.4.24.-] D M28_Spy1491 D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D M28_Spy0767 Xaa-His dipeptidase K01274 pepV; beta-Ala-Xaa dipeptidase [EC:3.4.13.-] D M28_Spy0593 pepT; peptidase T K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] D M28_Spy1095 map; methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D M28_Spy0411 pepQ; Xaa-Pro dipeptidase K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9] D M28_Spy1536 Xaa-Pro dipeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] D M28_Spy0013 ftsH; cell division protein K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D M28_Spy0095 pepA; glutamyl aminopeptidase K01261 pepA; glutamyl aminopeptidase [EC:3.4.11.7] D M28_Spy0272 heat shock protein HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D M28_Spy1662 pheromone-processing membrane metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] D M28_Spy1898 htrA; protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D M28_Spy0329 prtS; lactocepin K01361 E3.4.21.96; lactocepin [EC:3.4.21.96] D M28_Spy1700 scpA; C5A peptidase precursor K08652 C5AP; C5a peptidase [EC:3.4.21.110] D M28_Spy0243 dacA2; D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D M28_Spy0794 dacA1; D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D M28_Spy0317 clpP; ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D M28_Spy1565 pepXP; Xaa-Pro dipeptidyl-peptidase K01281 pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11] D M28_Spy1204 ATP-dependent protease La K07177 K07177; Lon-like protease D M28_Spy0886 phage transcriptional repressor K01356 lexA; repressor LexA [EC:3.4.21.88] D M28_Spy1553 spi; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D M28_Spy0959 sipC; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D M28_Spy0108 sipA; signal peptidase I protein SipA K03100 lepB; signal peptidase I [EC:3.4.21.89] D M28_Spy0471 peptidase family U32 K08303 prtC; U32 family peptidase [EC:3.4.-.-] C 01003 Glycosyltransferases [BR:spb01003] D M28_Spy0414 1,2-diacylglycerol 3-glucosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D M28_Spy0413 glycosyltransferase K13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208] D M28_Spy1396 pbp1A; multimodular transpeptidase-transglycosylase K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D M28_Spy0080 pbp1b; multimodular transpeptidase-transglycosylase PBP 1B K03693 pbp1b; penicillin-binding protein 1B D M28_Spy1739 pbp2A; multimodular transpeptidase-transglycosylase K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] D M28_Spy0235 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] C 01005 Lipopolysaccharide biosynthesis proteins [BR:spb01005] D M28_Spy0582 rgpAc; alpha-(1,2)-rhamnosyltransferase K12996 rgpA; rhamnosyltransferase [EC:2.4.1.-] D M28_Spy0583 rgpBc; alpha-L-Rha alpha-1,3-L-rhamnosyltransferase K12997 rgpB; rhamnosyltransferase [EC:2.4.1.-] D M28_Spy0586 rgpEc; glycosyltransferase K12998 rgpE; glucosyltransferase [EC:2.4.1.-] D M28_Spy0587 rgpFc; alpha-L-Rha alpha-1,2-L-rhamnosyltransferase K07272 rgpF; rhamnosyltransferase [EC:2.4.1.-] D M28_Spy0235 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D M28_Spy0408 glucosyltransferase K12999 rgpI; glucosyltransferase [EC:2.4.1.-] C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:spb01011] D M28_Spy0562 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D M28_Spy1099 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D M28_Spy0802 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D M28_Spy0282 murC; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D M28_Spy1192 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D M28_Spy0314 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--lysine ligase K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7] D M28_Spy1152 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D M28_Spy0892 UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10] D M28_Spy0490 murM; UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10] D M28_Spy0489 methicillin resistance expression factor K12554 murN; alanine adding enzyme [EC:2.3.2.-] D M28_Spy1522 acpS; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D M28_Spy0292 glr; glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D M28_Spy1407 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D M28_Spy1191 murG; UDP-GlcNAc--MurNAc-(pentapeptide) pyrophosphoryl-undecaprenol GlcNAc transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D M28_Spy0233 bacA; putative undecaprenol kinase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D M28_Spy0303 phosphatidylglycerophosphatase B-like protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D M28_Spy1396 pbp1A; multimodular transpeptidase-transglycosylase K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D M28_Spy0080 pbp1b; multimodular transpeptidase-transglycosylase PBP 1B K03693 pbp1b; penicillin-binding protein 1B D M28_Spy1739 pbp2A; multimodular transpeptidase-transglycosylase K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] D M28_Spy1408 division specific D,D-transpeptidase K12556 pbp2X; penicillin-binding protein 2X D M28_Spy0243 dacA2; D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D M28_Spy0794 dacA1; D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D M28_Spy1491 D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D M28_Spy0017 sibA; secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] D M28_Spy1703 mrp; emm related protein Mrp K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] D M28_Spy0106 srtC; class C sortase protein SrtC K07284 srtA; sortase A [EC:3.4.22.70] D M28_Spy0849 sortase K07284 srtA; sortase A [EC:3.4.22.70] D M28_Spy0110 srtB; class B sortase protein SrtB K08600 srtB; sortase B [EC:3.4.22.71] D M28_Spy0284 aminodeoxychorismate lyase family K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] C 01004 Lipid biosynthesis proteins [BR:spb01004] D M28_Spy1480 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D M28_Spy1483 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D M28_Spy1478 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D M28_Spy0348 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D M28_Spy1479 3-oxoacyl-[acyl-carrier protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D M28_Spy1476 fabZ; (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D M28_Spy1481 fabK; enoyl-[acyl-carrier protein] reductase (NADH) K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9] D M28_Spy1485 phaB; enoyl-CoA hydratase K18474 fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14] D M28_Spy0421 long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D M28_Spy0020 plsX; fatty acid/phospholipid synthesis protein K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D M28_Spy0690 putative membrane spanning protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D M28_Spy1145 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases [BR:spb01006] D M28_Spy1170 fps; dimethylallyltransferase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29] D M28_Spy1664 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D M28_Spy0702 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] C 01007 Amino acid related enzymes [BR:spb01007] D M28_Spy0197 gltX; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D M28_Spy0079 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D M28_Spy1891 trsA; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D M28_Spy1643 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D M28_Spy1817 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D M28_Spy0332 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D M28_Spy1182 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D M28_Spy1296 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D M28_Spy0145 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D M28_Spy0474 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D M28_Spy1822 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D M28_Spy0516 asnS; asnS K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D M28_Spy1823 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D M28_Spy1428 glyQ; glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D M28_Spy1427 glyS; glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D M28_Spy1472 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D M28_Spy1661 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D M28_Spy0415 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D M28_Spy1126 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D M28_Spy0566 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D M28_Spy0567 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D M28_Spy1502 aspartate aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D M28_Spy0693 bcaT; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D M28_Spy1682 para-aminobenzoate synthetase component I K03342 pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins [BR:spb00194] D M28_Spy0560 atpC; ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D M28_Spy0559 atpD; ATPase, beta subunit K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D M28_Spy0558 atpG; ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D M28_Spy0557 atpA; ATP synthase alpha chain K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D M28_Spy0556 atpH; ATP synthase delta chain K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D M28_Spy0555 atpF; ATP synthase B chain K02109 ATPF0B; F-type H+-transporting ATPase subunit b D M28_Spy0553 atpE; ATP synthase C chain K02110 ATPF0C; F-type H+-transporting ATPase subunit c D M28_Spy0554 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:spb03000] D M28_Spy0774 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D M28_Spy1445 lacR.1; lactose phosphotransferase system repressor K02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor D M28_Spy1629 lacR.2; lactose phosphotransferase system repressor K02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor D M28_Spy0641 fruR; fructose repressor K03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor D M28_Spy0412 ccpA; catabolite control protein A K02529 galR; LacI family transcriptional regulator, galactose operon repressor D M28_Spy1038 malR; transcriptional regulator, LacI family K02529 galR; LacI family transcriptional regulator, galactose operon repressor D M28_Spy1203 ribose operon repressor K02529 galR; LacI family transcriptional regulator, galactose operon repressor D M28_Spy0496 regR; transcriptional regulator, LacI family K02525 kdgR; LacI family transcriptional regulator, kdg operon repressor D M28_Spy1531 scrR; sucrose operon repressor K03484 scrR; LacI family transcriptional regulator, sucrose operon repressor D M28_Spy1356 transcriptional regulator, GntR family K02103 araR; GntR family transcriptional regulator, arabinose operon transcriptional repressor D M28_Spy1769 trehalose operon transcriptional repressor K03486 treR2; GntR family transcriptional regulator, trehalose operon transcriptional repressor D M28_Spy0889 transcriptional regulator, GntR family K24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator D M28_Spy0522 transcriptional regulator, GntR family K24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator D M28_Spy1589 transcriptional regulator, MerR family K03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor D M28_Spy0159 perR; ferric uptake regulation protein K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator D M28_Spy1214 transcription regulator, crp family K21828 arcR; CRP/FNR family transcriptional regulator, arginine deiminase pathway regulator D M28_Spy1827 cadC; cadmium efflux system accessory protein K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor D M28_Spy1835 transcriptional regulator, PadR family K10947 K10947; PadR family transcriptional regulator D M28_Spy0356 scaR; iron-dependent repressor K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D M28_Spy1102 birA; biotin operon repressor K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D M28_Spy0034 comR; competence transcriptional regulator ComR K20342 comR; HTH-type transcriptional regulator, regulator for ComX D M28_Spy0395 mutR; transcriptional regulator K20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator D M28_Spy0428 transcriptional regulator K20374 rgg3; HTH-type transcriptional regulator, SHP3-responsive repressor D M28_Spy1724 rgg; transcriptional regulator K20375 ropB; HTH-type transcriptional regulator, pheromone-responsive regulator D M28_Spy0222 purR; pur operon repressor K09685 purR; HTH-type transcriptional regulator, purine operon repressor D M28_Spy0818 redox-sensitive transcriptional regulator Rex K01926 rex; redox-sensing transcriptional repressor D M28_Spy1501 codY; transcription pleiotropic repressor K03706 codY; transcriptional pleiotropic repressor D M28_Spy1793 phage transcriptional repressor K07726 K07726; putative transcriptional regulator D M28_Spy1021 phage protein K07727 K07727; putative transcriptional regulator D M28_Spy1125 transcriptional regulator, Cro/CI family K07729 K07729; putative transcriptional regulator D M28_Spy1636 transcriptional regulator, Cro/CI family K07729 K07729; putative transcriptional regulator D M28_Spy1841 hypothetical protein K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB D M28_Spy0455 licT; transcription antiterminator, BglG family K03488 licT; beta-glucoside operon transcriptional antiterminator D M28_Spy0153 transcription antiterminator, BglG family K03493 bglG1; transcriptional antiterminator D M28_Spy1064 transcription antiterminator, BglG family K03491 licR; probable licABCH operon transcriptional regulator D M28_Spy1899 parB; chromosome partitioning protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D M28_Spy1255 ParB-like protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D M28_Spy1816 argR2; arginine repressor K03402 argR; transcriptional regulator of arginine metabolism D M28_Spy1215 ahrC.2; arginine repressor K03402 argR; transcriptional regulator of arginine metabolism D M28_Spy1168 argR1; arginine repressor K03402 argR; transcriptional regulator of arginine metabolism D M28_Spy1489 hrcA; heat-inducible transcription repressor K03705 hrcA; heat-inducible transcriptional repressor D M28_Spy1750 ctsR; transcriptional regulator K03708 ctsR; transcriptional regulator of stress and heat shock response D M28_Spy0619 pyrR; bifunctional pyrimidine regulatory protein PyrR K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9] D M28_Spy0276 putative regulatory protein K07738 nrdR; transcriptional repressor NrdR D M28_Spy0251 comX; competence-specific sigma factor ComX K12296 comX1_2; competence protein ComX D M28_Spy1607 comX.2; competence-specific sigma factor K12296 comX1_2; competence protein ComX C 03021 Transcription machinery [BR:spb03021] D M28_Spy0069 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D M28_Spy0081 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D M28_Spy0082 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D M28_Spy1600 rpoE; DNA-directed RNA polymerase delta chain K03048 rpoE; DNA-directed RNA polymerase subunit delta D M28_Spy1381 DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D M28_Spy0579 rpoD; RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor D M28_Spy1455 nusA; N utilization substance protein A K02600 nusA; transcription termination/antitermination protein NusA D M28_Spy1532 nusB; N utilization substance protein B K03625 nusB; transcription antitermination protein NusB D M28_Spy0136 nusG; transcription antitermination protein K02601 nusG; transcription termination/antitermination protein NusG D M28_Spy0285 greA; transcription elongation factor K03624 greA; transcription elongation factor GreA C 03019 Messenger RNA biogenesis [BR:spb03019] D M28_Spy0426 acpA; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D M28_Spy1587 Zn-dependent hydrolase K12574 rnj; ribonuclease J [EC:3.1.-.-] D M28_Spy0726 Zn-dependent hydrolase K12574 rnj; ribonuclease J [EC:3.1.-.-] D M28_Spy1383 hydrolase (HAD superfamily) K18682 rny; ribonucrease Y [EC:3.1.-.-] D M28_Spy0402 exoribonuclease II K12573 rnr; ribonuclease R [EC:3.1.13.1] D M28_Spy0221 cbf; CMP-binding factor K03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-] D M28_Spy1148 deaD; ATP-dependent RNA helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D M28_Spy1406 ATP-dependent RNA helicase K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7] D M28_Spy0535 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D M28_Spy1648 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D M28_Spy0961 pfk; non-allosteric 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D M28_Spy1487 dnaK; chaperone protein K04043 dnaK; molecular chaperone DnaK D M28_Spy1747 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D M28_Spy0517 ATP-binding protein K06958 rapZ; RNase adapter protein RapZ C 03041 Spliceosome C 03011 Ribosome [BR:spb03011] D M28_Spy0695 SSU ribosomal protein S1P K02945 RP-S1; small subunit ribosomal protein S1 D M28_Spy1764 rpsB; SSU ribosomal protein S2P K02967 RP-S2; small subunit ribosomal protein S2 D M28_Spy0049 rpsC; SSU ribosomal protein S3P K02982 RP-S3; small subunit ribosomal protein S3 D M28_Spy1865 rpsD; SSU ribosomal protein S4P K02986 RP-S4; small subunit ribosomal protein S4 D M28_Spy0060 rpsE; SSU ribosomal protein S5P K02988 RP-S5; small subunit ribosomal protein S5 D M28_Spy1542 rpsF; SSU ribosomal protein S6P K02990 RP-S6; small subunit ribosomal protein S6 D M28_Spy0225 rpsG; SSU ribosomal protein S7P K02992 RP-S7; small subunit ribosomal protein S7 D M28_Spy0057 rpsH; SSU ribosomal protein S8P K02994 RP-S8; small subunit ribosomal protein S8 D M28_Spy1634 rpsI; SSU ribosomal protein S9P K02996 RP-S9; small subunit ribosomal protein S9 D M28_Spy0042 rpsJ; SSU ribosomal protein S10P K02946 RP-S10; small subunit ribosomal protein S10 D M28_Spy0068 rpsK; SSU ribosomal protein S11P K02948 RP-S11; small subunit ribosomal protein S11 D M28_Spy0224 rpsL; SSU ribosomal protein S12P K02950 RP-S12; small subunit ribosomal protein S12 D M28_Spy0067 rpsM; SSU ribosomal protein S13P K02952 RP-S13; small subunit ribosomal protein S13 D M28_Spy0056 rpsN; SSU ribosomal protein S14P K02954 RP-S14; small subunit ribosomal protein S14 D M28_Spy1582 rpsN2; SSU ribosomal protein S14P K02954 RP-S14; small subunit ribosomal protein S14 D M28_Spy1654 SSU ribosomal protein S15P K02956 RP-S15; small subunit ribosomal protein S15 D M28_Spy0629 rpsP; SSU ribosomal protein S16P K02959 RP-S16; small subunit ribosomal protein S16 D M28_Spy0052 rpsQ; SSU ribosomal protein S17P K02961 RP-S17; small subunit ribosomal protein S17 D M28_Spy1540 rpsR; SSU ribosomal protein S18P K02963 RP-S18; small subunit ribosomal protein S18 D M28_Spy0047 rpsS; SSU ribosomal protein S19P K02965 RP-S19; small subunit ribosomal protein S19 D M28_Spy0918 rpsT; SSU ribosomal protein S20P K02968 RP-S20; small subunit ribosomal protein S20 D M28_Spy0576 SSU ribosomal protein S21P K02970 RP-S21; small subunit ribosomal protein S21 D M28_Spy0364 rplA; LSU ribosomal protein L1P K02863 RP-L1; large subunit ribosomal protein L1 D M28_Spy0046 rplB; LSU ribosomal protein L2P K02886 RP-L2; large subunit ribosomal protein L2 D M28_Spy0043 rplC; LSU ribosomal protein L3P K02906 RP-L3; large subunit ribosomal protein L3 D M28_Spy0044 rplD; LSU ribosomal protein L1E K02926 RP-L4; large subunit ribosomal protein L4 D M28_Spy0055 rplE; LSU ribosomal protein L5P K02931 RP-L5; large subunit ribosomal protein L5 D M28_Spy0058 rplF; LSU ribosomal protein L6P K02933 RP-L6; large subunit ribosomal protein L6 D M28_Spy1868 rplI; LSU ribosomal protein L9P K02939 RP-L9; large subunit ribosomal protein L9 D M28_Spy0769 rplJ; LSU ribosomal protein L10P K02864 RP-L10; large subunit ribosomal protein L10 D M28_Spy0363 rplK; LSU ribosomal protein L11P K02867 RP-L11; large subunit ribosomal protein L11 D M28_Spy0770 rplL; LSU ribosomal protein L7/L12P K02935 RP-L7; large subunit ribosomal protein L7/L12 D M28_Spy1635 rplM; LSU ribosomal protein L13P K02871 RP-L13; large subunit ribosomal protein L13 D M28_Spy0053 rplN; LSU ribosomal protein L14P K02874 RP-L14; large subunit ribosomal protein L14 D M28_Spy0062 rplO; LSU ribosomal protein L15P K02876 RP-L15; large subunit ribosomal protein L15 D M28_Spy0050 rplP; LSU ribosomal protein L16P K02878 RP-L16; large subunit ribosomal protein L16 D M28_Spy0070 rplQ; LSU ribosomal protein L17P K02879 RP-L17; large subunit ribosomal protein L17 D M28_Spy0059 rplR; LSU ribosomal protein L18P K02881 RP-L18; large subunit ribosomal protein L18 D M28_Spy0529 rplS; LSU ribosomal protein L19P K02884 RP-L19; large subunit ribosomal protein L19 D M28_Spy0600 rplT; LSU ribosomal protein L20P K02887 RP-L20; large subunit ribosomal protein L20 D M28_Spy0613 rplU; LSU ribosomal protein L21P K02888 RP-L21; large subunit ribosomal protein L21 D M28_Spy0048 rplV; LSU ribosomal protein L22P K02890 RP-L22; large subunit ribosomal protein L22 D M28_Spy0045 rplW; LSU ribosomal protein L23P K02892 RP-L23; large subunit ribosomal protein L23 D M28_Spy0054 rplX; LSU ribosomal protein L24P K02895 RP-L24; large subunit ribosomal protein L24 D M28_Spy0615 rpmA; LSU ribosomal protein L27P K02899 RP-L27; large subunit ribosomal protein L27 D M28_Spy1596 rpmB; LSU ribosomal protein L28P K02902 RP-L28; large subunit ribosomal protein L28 D M28_Spy0051 rpmC; LSU ribosomal protein L29P K02904 RP-L29; large subunit ribosomal protein L29 D M28_Spy0061 rpmD; LSU ribosomal protein L30P K02907 RP-L30; large subunit ribosomal protein L30 D M28_Spy0524 rpmE; LSU ribosomal protein L31P K02909 RP-L31; large subunit ribosomal protein L31 D M28_Spy1824 rpmF; LSU ribosomal protein L32P K02911 RP-L32; large subunit ribosomal protein L32 D M28_Spy1738 LSU ribosomal protein L33P K02913 RP-L33; large subunit ribosomal protein L33 D M28_Spy1825 rpmG; LSU ribosomal protein L33P K02913 RP-L33; large subunit ribosomal protein L33 D M28_Spy0400 LSU ribosomal protein L33P K02913 RP-L33; large subunit ribosomal protein L33 D M28_Spy0205 rpmH; LSU ribosomal protein L34P K02914 RP-L34; large subunit ribosomal protein L34 D M28_Spy0599 rpl36; LSU ribosomal protein L35P K02916 RP-L35; large subunit ribosomal protein L35 D M28_Spy0066 rpmJ; LSU ribosomal protein L36P K02919 RP-L36; large subunit ribosomal protein L36 D M28_SpyR0003 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_SpyR0012 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_SpyR0006 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_SpyR0009 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_SpyR0013 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_SpyR0016 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_SpyR0018 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0015 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0001 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0010 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0004 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0007 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0002 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0008 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0011 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0005 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0017 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0014 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 03009 Ribosome biogenesis [BR:spb03009] D M28_Spy0426 acpA; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D M28_Spy0376 era; putative GTP-binding protein K03595 era; GTPase D M28_Spy1069 obg; GTP-binding protein OBG family K03979 obgE; GTPase [EC:3.6.5.-] D M28_Spy1455 nusA; N utilization substance protein A K02600 nusA; transcription termination/antitermination protein NusA D M28_Spy1532 nusB; N utilization substance protein B K03625 nusB; transcription antitermination protein NusB D M28_Spy0136 nusG; transcription antitermination protein K02601 nusG; transcription termination/antitermination protein NusG D M28_Spy1073 rsuA; ribosomal small subunit pseudouridine synthase A K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19] D M28_Spy1132 ribosomal small subunit pseudouridine synthase A K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19] D M28_Spy0216 ksgA; dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D M28_Spy1378 sunL; 16S rRNA m(5)C 967 methyltransferase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D M28_Spy0916 16S rRNA m(2)G 1207 methyltransferase K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172] D M28_Spy1206 methyltransferase K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171] D M28_Spy1679 putative cytosolic protein K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193] D M28_Spy0270 gidB; glucose inhibited division protein B K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D M28_Spy1410 mraW; S-adenosyl-methyltransferase K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199] D M28_Spy0323 corrin/porphyrin methyltransferase K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198] D M28_Spy1169 hemolysin K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227] D M28_Spy1640 23S rRNA methyltransferase K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185] D M28_Spy1897 putative cytosolic protein K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177] D M28_Spy0602 methyltransferase K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191] D M28_Spy1200 radical SAM family enzyme K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192] D M28_Spy1090 tRNA (uracil-5-)-methyltransferase K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190] D M28_Spy0299 ribosomal large subunit pseudouridine synthase B K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22] D M28_Spy0825 ribosomal large subunit pseudouridine synthase D K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D M28_Spy1742 ribosomal large subunit pseudouridine synthase D K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D M28_Spy0618 ribosomal large subunit pseudouridine synthase D K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D M28_Spy1584 ribosomal-protein-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D M28_Spy0636 rimM; 16S rRNA processing protein K02860 rimM; 16S rRNA processing protein RimM D M28_Spy1680 ribosomal protein L11 methyltransferase K02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-] D M28_Spy1780 hypothetical protein K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-] D M28_Spy1642 hypothetical protein K11145 mrnC; mini-ribonuclease III [EC:3.1.26.-] D M28_Spy1148 deaD; ATP-dependent RNA helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D M28_Spy1406 ATP-dependent RNA helicase K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7] D M28_Spy0217 GTPase K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D M28_Spy0279 pgdA; GTP-binding protein K03977 engA; GTPase D M28_Spy0856 GTP-binding protein K14540 rbgA; ribosome biogenesis GTPase A D M28_Spy0703 hflX; GTP-binding protein K03665 hflX; GTPase D M28_Spy0253 GTP-binding protein K06948 yqeH; 30S ribosome assembly GTPase D M28_Spy0839 SUA5 protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D M28_Spy1674 relA; GTP pyrophosphokinase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D M28_Spy1451 rbfA; ribosome-binding factor A K02834 rbfA; ribosome-binding factor A D M28_Spy1456 putative cytosolic protein K09748 rimP; ribosome maturation factor RimP D M28_Spy1887 putative cytosolic protein K14761 rlbA; ribosome-associated protein D M28_Spy0257 iojap protein family K09710 ybeB; ribosome-associated protein D M28_Spy0374 putative metal-binding protein K07042 ybeY; probable rRNA maturation factor D M28_Spy0254 putative RNA binding protein K07574 yhbY; RNA-binding protein D M28_Spy1366 ribosome-associated factor Y K05808 hpf; ribosome hibernation promoting factor D M28_Spy0004 GTP-binding protein K06942 ychF; ribosome-binding ATPase D M28_Spy0273 putative cytosolic protein K07040 yceD; DUF177 domain-containing protein C 03016 Transfer RNA biogenesis [BR:spb03016] D M28_Spy0705 elaC; metal-dependent hydrolase K00784 rnz; ribonuclease Z [EC:3.1.26.11] D M28_Spy0653 papS; poly(A) polymerase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] D M28_Spy1661 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D M28_Spy1182 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D M28_Spy0145 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D M28_Spy0332 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D M28_Spy1817 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D M28_Spy0474 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D M28_Spy1822 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D M28_Spy1126 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D M28_Spy0516 asnS; asnS K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D M28_Spy0415 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D M28_Spy1472 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D M28_Spy1643 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D M28_Spy1296 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D M28_Spy1823 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D M28_Spy0566 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D M28_Spy0567 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D M28_Spy0079 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D M28_Spy1891 trsA; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D M28_Spy1673 D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96] D M28_Spy1461 hit; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D M28_Spy1457 tRNA (m(7)G46) methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] D M28_Spy1606 tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D M28_Spy0934 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D M28_Spy0610 nifS1; cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D M28_Spy0820 nifS2; cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D M28_Spy0839 SUA5 protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D M28_Spy0702 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D M28_Spy0768 thdF; tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-] D M28_Spy1870 gidA; glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D M28_Spy0201 fasX; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5] D M28_Spy1428 glyQ; glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D M28_Spy1427 glyS; glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D M28_Spy0197 gltX; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D M28_Spy0477 transcriptional regulator K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-] D M28_Spy0177 tRNA-specific adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33] D M28_Spy0102 tRNA-dihydrouridine synthase K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-] D M28_Spy0866 gid; glucose inhibited division protein A K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74] D M28_Spy0637 trmD; tRNA (guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D M28_Spy0711 para-aminobenzoate synthase component I K06967 trmK; tRNA (adenine22-N1)-methyltransferase [EC:2.1.1.217] D M28_Spy0301 23S rRNA methyltransferase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207] D M28_Spy0288 23S rRNA methyltransferase K03437 spoU; RNA methyltransferase, TrmH family D M28_Spy1872 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D M28_Spy1134 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17] D M28_Spy0508 iron-sulfur cluster-binding protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6] D M28_Spy0192 putative cytosolic protein K09765 queH; epoxyqueuosine reductase [EC:1.17.99.6] D M28_Spy0173 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29] D M28_Spy0611 thiI; thiamine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D M28_Spy0011 tilS; tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19] D M28_Spy1585 glycoprotease protein family K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB D M28_Spy1583 O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234] D M28_Spy1465 ATP/GTP hydrolase K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE D M28_Spy0259 putative cytosolic protein K27343 tmcAL; tRNA(Met) cytidine acetate ligase [EC:6.3.4.-] D M28_Spy0402 exoribonuclease II K12573 rnr; ribonuclease R [EC:3.1.13.1] D M28_Spy1648 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] C 03012 Translation factors [BR:spb03012] D M28_Spy1452 infB; bacterial protein translation initiation factor 2 (IF-2) K02519 infB; translation initiation factor IF-2 D M28_Spy0598 infC; bacterial protein translation initiation factor 3 (IF-3) K02520 infC; translation initiation factor IF-3 D M28_Spy0729 ABC transporter ATP-binding protein K06158 ABCF3; ATP-binding cassette, subfamily F, member 3 D M28_Spy1765 protein translation elongation factor Ts (EF-Ts) K02357 tsf; elongation factor Ts D M28_Spy0487 protein translation elongation factor Tu (EF-TU) K02358 tuf; elongation factor Tu D M28_Spy0226 fus; protein translation elongation factor G K02355 fusA; elongation factor G D M28_Spy0837 prfA; bacterial peptide chain release factor 1 K02835 prfA; peptide chain release factor 1 D M28_Spy0366 rrf; ribosome recycling factor K02838 frr; ribosome recycling factor D M28_Spy0838 hemK; peptide release factor-glutamine N5-methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D M28_Spy0005 pth; peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] D M28_Spy0065 infA; bacterial protein translation initiation factor 1 (IF-1) K02518 infA; translation initiation factor IF-1 D M28_Spy1534 efp; protein translation elongation factor P K02356 efp; elongation factor P D M28_Spy0509 prfB; bacterial peptide chain release factor 2 K02836 prfB; peptide chain release factor 2 D M28_Spy1149 prfC; bacterial peptide chain release factor 3 K02837 prfC; peptide chain release factor 3 C 03110 Chaperones and folding catalysts [BR:spb03110] D M28_Spy1749 clpC; negative regulator of genetic competence K03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC D M28_Spy1179 clpE; ATP-dependent Clp protease ATP-binding subunit K03697 clpE; ATP-dependent Clp protease ATP-binding subunit ClpE D M28_Spy0674 clpL; ATP-dependent protease ATP-binding subunit K04086 clpL; ATP-dependent Clp protease ATP-binding subunit ClpL D M28_Spy0671 clpX; ATP-dependent Clp protease ATP-binding subunit K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX D M28_Spy1487 dnaK; chaperone protein K04043 dnaK; molecular chaperone DnaK D M28_Spy1747 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D M28_Spy1486 dnaJ; chaperone protein K03686 dnaJ; molecular chaperone DnaJ D M28_Spy0103 putative HSP33 K04083 hslO; molecular chaperone Hsp33 D M28_Spy1488 grpE; grpE K03687 GRPE; molecular chaperone GrpE D M28_Spy1748 groES; 10 kDa chaperonin K04078 groES; chaperonin GroES D M28_Spy1898 htrA; protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D M28_Spy0013 ftsH; cell division protein K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D M28_Spy0554 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a D M28_Spy0329 prtS; lactocepin K01361 E3.4.21.96; lactocepin [EC:3.4.21.96] D M28_Spy1700 scpA; C5A peptidase precursor K08652 C5AP; C5a peptidase [EC:3.4.21.110] D M28_Spy0360 peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D M28_Spy1372 peptidyl-prolyl cis-trans isomerase K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] D M28_Spy1718 protein export protein prsA precursor K07533 prsA; foldase protein PrsA [EC:5.2.1.8] D M28_Spy1127 surA; peptidyl-prolyl cis-trans isomerase K07533 prsA; foldase protein PrsA [EC:5.2.1.8] D M28_Spy1547 trx.2; thioredoxin K03671 TXN; thioredoxin C 04131 Membrane trafficking [BR:spb04131] D M28_Spy1358 alpha-mannosidase K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24] D M28_Spy0227 plr; glyceraldehyde 3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D M28_Spy1158 gpmA; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D M28_Spy0960 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] C 04121 Ubiquitin system C 03051 Proteasome C 03032 DNA replication proteins [BR:spb03032] D M28_Spy0774 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D M28_Spy1162 DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta D M28_Spy0001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein D M28_Spy1867 holB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D M28_Spy0578 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D M28_Spy0277 dnaB; replicative DNA helicase K03346 dnaB; replication initiation and membrane attachment protein D M28_Spy0278 dnaI; primosomal protein K11144 dnaI; primosomal protein DnaI D M28_Spy0100 ssb; single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy1541 ssb2.2; phage single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy1268 ssb2.1; phage single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy0962 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D M28_Spy1660 polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D M28_Spy0002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D M28_Spy1140 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D M28_Spy0320 dnaX; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D M28_Spy1570 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D M28_Spy1105 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D M28_Spy0857 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D M28_Spy1552 ribonuclease HIII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4] D M28_Spy0157 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D M28_Spy0551 lig; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D M28_Spy0848 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D M28_Spy0532 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D M28_Spy0692 parC; topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D M28_Spy0691 parE; topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D M28_Spy0859 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] C 03036 Chromosome and associated proteins [BR:spb03036] D M28_Spy0774 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D M28_Spy0426 acpA; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D M28_Spy1162 DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta D M28_Spy0001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein D M28_Spy1198 dpr; non-specific DNA-binding protein Dps K04047 dps; starvation-inducible DNA-binding protein D M28_Spy0427 smc; chromosome partition protein smc K03529 smc; chromosome segregation protein D M28_Spy0297 putative cytosolic protein K05896 scpA; segregation and condensation protein A D M28_Spy0298 putative cytosolic protein K06024 scpB; segregation and condensation protein B D M28_Spy1189 ftsA; cell division protein K03590 ftsA; cell division protein FtsA D M28_Spy0008 divIC; cell division protein K13052 divIC; cell division protein DivIC D M28_Spy0510 ftsE; cell division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein D M28_Spy0361 ftsK; cell division protein K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family D M28_Spy1409 ftsL; cell division protein K03586 ftsL; cell division protein FtsL D M28_Spy1190 divIB; cell division protein K03589 ftsQ; cell division protein FtsQ D M28_Spy0485 ftsW; cell division protein K03588 ftsW; cell division protein FtsW D M28_Spy0511 ftsX; cell division protein K09811 ftsX; cell division transport system permease protein D M28_Spy1188 ftsZ; cell division protein K03531 ftsZ; cell division protein FtsZ D M28_Spy0533 septation ring formation regulator K06286 ezrA; septation ring formation regulator D M28_Spy1183 divIVAS; cell division initiation protein DivIVA K04074 divIVA; cell division initiation protein D M28_Spy1186 putative cytosolic protein K09772 sepF; cell division inhibitor SepF D M28_Spy1899 parB; chromosome partitioning protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D M28_Spy1255 ParB-like protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D M28_Spy0692 parC; topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D M28_Spy0691 parE; topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D M28_Spy1870 gidA; glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D M28_Spy0270 gidB; glucose inhibited division protein B K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D M28_Spy0866 gid; glucose inhibited division protein A K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74] D M28_Spy0672 GTP-binding protein K03978 engB; GTP-binding protein D M28_Spy0519 putative cytosolic protein K09762 whiA; cell division protein WhiA C 03400 DNA repair and recombination proteins [BR:spb03400] D M28_Spy1175 phr; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D M28_Spy0688 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D M28_Spy1544 mutY; A/G-specific adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D M28_Spy0710 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D M28_Spy0717 mutator protein T K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D M28_Spy1180 mutT; mutator protein (7,8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D M28_Spy0193 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D M28_Spy1785 tag; DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D M28_Spy0396 fpg; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D M28_Spy0327 exoA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D M28_Spy0707 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D M28_Spy0551 lig; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D M28_Spy0157 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D M28_Spy1537 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A D M28_Spy1056 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B D M28_Spy0765 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C D M28_Spy0949 pcrA; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D M28_Spy0081 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D M28_Spy0082 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D M28_Spy0069 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D M28_Spy1600 rpoE; DNA-directed RNA polymerase delta chain K03048 rpoE; DNA-directed RNA polymerase subunit delta D M28_Spy1381 DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D M28_Spy0006 trcF; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D M28_Spy1814 mutS; DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS D M28_Spy1549 mutS2; DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2 D M28_Spy1788 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL D M28_Spy1172 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D M28_Spy1171 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D M28_Spy0962 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D M28_Spy1660 polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D M28_Spy0002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D M28_Spy1140 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D M28_Spy0320 dnaX; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D M28_Spy1570 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D M28_Spy1105 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D M28_Spy0100 ssb; single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy1541 ssb2.2; phage single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy1268 ssb2.1; phage single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy1554 recD; exodeoxyribonuclease V alpha chain K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D M28_Spy1783 recA; DNA recombinase RecA K03553 recA; recombination protein RecA D M28_Spy1786 ruvA; holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA D M28_Spy0035 ruvB; holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D M28_Spy1380 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D M28_Spy0194 radA; DNA repair protein K04485 radA; DNA repair protein RadA/Sms D M28_Spy1888 recF; DNA replication and repair protein recF K03629 recF; DNA replication and repair protein RecF D M28_Spy1509 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D M28_Spy0019 recO; DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O) D M28_Spy1153 recR; recombination protein K06187 recR; recombination protein RecR D M28_Spy1167 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N) D M28_Spy1395 recU; recombination protein K03700 recU; recombination protein U D M28_Spy0574 rexA; ATP-dependent nuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-] D M28_Spy0573 rexB; ATP-dependent nuclease subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-] D M28_Spy1290 cas1; Type I-C CRISPR associated endonuclease, Cas1 K15342 cas1; CRISP-associated protein Cas1 D M28_Spy0749 cas1; Type II CRISPR associated endonuclease, Cas1 K15342 cas1; CRISP-associated protein Cas1 D M28_Spy0398 ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase D M28_Spy0848 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D M28_Spy0532 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D M28_Spy0859 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D M28_Spy1162 DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta D M28_Spy1556 dinP; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D M28_Spy0886 phage transcriptional repressor K01356 lexA; repressor LexA [EC:3.4.21.88] D M28_Spy1361 recX; regulatory protein K03565 recX; regulatory protein D M28_Spy0514 dinG; ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D M28_Spy0336 nrdE.1; ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D M28_Spy1116 nrdE.2; ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D M28_Spy0334 nrdF.1; ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D M28_Spy1118 nrdF.2; ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D M28_Spy0525 phosphoesterase, DHH family protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] C 03029 Mitochondrial biogenesis [BR:spb03029] D M28_Spy1452 infB; bacterial protein translation initiation factor 2 (IF-2) K02519 infB; translation initiation factor IF-2 D M28_Spy0598 infC; bacterial protein translation initiation factor 3 (IF-3) K02520 infC; translation initiation factor IF-3 D M28_Spy1765 protein translation elongation factor Ts (EF-Ts) K02357 tsf; elongation factor Ts D M28_Spy0487 protein translation elongation factor Tu (EF-TU) K02358 tuf; elongation factor Tu D M28_Spy0226 fus; protein translation elongation factor G K02355 fusA; elongation factor G D M28_Spy0376 era; putative GTP-binding protein K03595 era; GTPase D M28_Spy0079 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D M28_Spy0145 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D M28_Spy1822 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D M28_Spy1817 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D M28_Spy1496 gatA; aspartyl/glutamyl-tRNA amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D M28_Spy1495 gatB; aspartyl/glutamyl-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D M28_Spy1497 gatC; glutamyl-tRNA(Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D M28_Spy0100 ssb; single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy1541 ssb2.2; phage single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy1268 ssb2.1; phage single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D M28_Spy1487 dnaK; chaperone protein K04043 dnaK; molecular chaperone DnaK D M28_Spy1488 grpE; grpE K03687 GRPE; molecular chaperone GrpE D M28_Spy1747 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D M28_Spy1748 groES; 10 kDa chaperonin K04078 groES; chaperonin GroES D M28_Spy1486 dnaJ; chaperone protein K03686 dnaJ; molecular chaperone DnaJ D M28_Spy0610 nifS1; cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D M28_Spy0820 nifS2; cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D M28_Spy0202 hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D M28_Spy0286 inner membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:spb02000] D M28_Spy0782 srtT; ABC transporter (ATP binding)-lantibiotic associated K20485 nisT; ATP-binding cassette, subfamily B, bacterial NisT/SpaT D M28_Spy0190 ABC transporter ATP-binding and permease protein K18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump D M28_Spy0191 ABC transporter ATP-binding and permease protein K18892 patB; ATP-binding cassette, subfamily B, multidrug efflux pump D M28_Spy0844 multidrug resistance ABC transporter ATP-binding and permease protein K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump D M28_Spy0845 multidrug resistance ABC transporter ATP-binding and permease protein K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump D M28_Spy1514 ABC transporter ATP-binding protein K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial D M28_Spy1515 ABC transporter ATP-binding protein K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial D M28_Spy0654 ABC transporter ATP-binding protein uup K15738 uup; ABC transport system ATP-binding/permease protein D M28_Spy0763 iron(III)-binding protein K02012 afuA; iron(III) transport system substrate-binding protein D M28_Spy0806 spermidine/putrescine-binding protein K11069 potD; spermidine/putrescine transport system substrate-binding protein D M28_Spy0805 potC; spermidine/putrescine transport system permease protein K11070 potC; spermidine/putrescine transport system permease protein D M28_Spy0804 potB; spermidine/putrescine transport system permease protein K11071 potB; spermidine/putrescine transport system permease protein D M28_Spy0803 potA; spermidine/putrescine transport ATP-binding protein K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11] D M28_Spy0156 opuABC; glycine betaine-binding protein K02001 proW; glycine betaine/proline transport system permease protein D M28_Spy0155 opuAA; glycine betaine transport ATP-binding protein K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9] D M28_Spy0830 glycine betaine transport system permease protein K05845 opuC; osmoprotectant transport system substrate-binding protein D M28_Spy0829 proV; glycine betaine transport ATP-binding protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9] D M28_Spy1670 msmK; multiple sugar transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D M28_Spy1048 malX; maltose/maltodextrin-binding protein K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein D M28_Spy1039 malE; maltose/maltodextrin-binding protein K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein D M28_Spy1040 malF; maltose transport system permease protein K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D M28_Spy1045 malC; maltose transport system permease protein K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D M28_Spy1041 malG; maltose transport system permease protein K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D M28_Spy1044 malD; maltodextrin transport system permease protein K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D M28_Spy1349 sugar-binding protein K17318 lplA; putative aldouronate transport system substrate-binding protein D M28_Spy1351 sugar transport system permease protein K17319 lplB; putative aldouronate transport system permease protein D M28_Spy1350 sugar transport system permease protein K17320 lplC; putative aldouronate transport system permease protein D M28_Spy0914 nucleoside-binding protein K07335 bmpA; basic membrane protein A and related proteins D M28_Spy0135 nucleoside-binding protein K07335 bmpA; basic membrane protein A and related proteins D M28_Spy0912 nucleoside transport system permease protein K23535 nupB; general nucleoside transport system permease protein D M28_Spy0911 nucleoside transport system permease protein K23536 nupC; general nucleoside transport system permease protein D M28_Spy0913 nucleoside transport ATP-binding protein K23537 nupA; general nucleoside transport system ATP-binding protein D M28_Spy0207 N-acetylneuraminate-binding protein K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D M28_Spy0208 N-acetylneuraminate transport system permease protein K02025 ABC.MS.P; multiple sugar transport system permease protein D M28_Spy0209 N-acetylneuraminate transport system permease protein K02026 ABC.MS.P1; multiple sugar transport system permease protein D M28_Spy0928 pstS; phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D M28_Spy0927 pstC; phosphate transport system permease protein K02037 pstC; phosphate transport system permease protein D M28_Spy0926 pstA; phosphate transport system permease protein K02038 pstA; phosphate transport system permease protein D M28_Spy0924 pstB; phosphate transport ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D M28_Spy0925 pstB2; phosphate transport ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D M28_Spy1057 glnH; transporter K10036 glnH; glutamine transport system substrate-binding protein D M28_Spy1058 glnQ.2; glutamine transport ATP-binding protein K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1] D M28_Spy0686 cystine-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D M28_Spy0262 ABC transporter substrate-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D M28_Spy0687 cystine transport system permease protein K10009 tcyB; L-cystine transport system permease protein D M28_Spy1404 amino acid ABC transporter permease protein K10009 tcyB; L-cystine transport system permease protein D M28_Spy1403 transporter K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1] D M28_Spy0575 arginine-binding protein K23059 artP; arginine/lysine/histidine transporter system substrate-binding protein D M28_Spy1177 artQ; arginine transport system permease protein K17077 artQ; arginine/lysine/histidine transport system permease protein D M28_Spy1176 artP; arginine transport ATP-binding protein K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1] D M28_Spy0263 ABC transporter substrate-binding protein K02073 metQ; D-methionine transport system substrate-binding protein D M28_Spy0265 ABC transporter permease protein K02072 metI; D-methionine transport system permease protein D M28_Spy0264 ABC transporter ATP-binding protein K02071 metN; D-methionine transport system ATP-binding protein D M28_Spy0722 ABC transporter substrate-binding protein K01989 K01989; putative tryptophan/tyrosine transport system substrate-binding protein D M28_Spy0724 ABC transporter permease protein K05832 K05832; putative tryptophan/tyrosine transport system permease protein D M28_Spy0725 ABC transporter ATP-binding protein K05833 K05833; putative tryptophan/tyrosine transport system ATP-binding protein D M28_Spy0230 ABC transporter amino acid-binding protein K17073 lysX1; putative lysine transport system substrate-binding protein D M28_Spy0229 amino acid transport ATP-binding protein K17076 lysY; putative lysine transport system ATP-binding protein D M28_Spy0954 histidine-binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein D M28_Spy0956 histidine transport system permease protein M K02029 ABC.PA.P; polar amino acid transport system permease protein D M28_Spy0955 histidine transport ATP-binding protein P K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1] D M28_Spy0244 oppA; oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein D M28_Spy0245 oppB; oligopeptide transport system permease protein K15581 oppB; oligopeptide transport system permease protein D M28_Spy0246 oppC; oligopeptide transport system permease protein K15582 oppC; oligopeptide transport system permease protein D M28_Spy0247 oppD; oligopeptide transport ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein D M28_Spy0248 oppF; oligopeptide transport ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein D M28_Spy1689 dppA; dipeptide-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D M28_Spy1690 dppB; dipeptide transport system permease protein K02033 ABC.PE.P; peptide/nickel transport system permease protein D M28_Spy1691 dppC; dipeptide transport system permease protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein D M28_Spy1692 dppD; dipeptide transport ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D M28_Spy1693 dppE; dipeptide transport ATP-binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein D M28_Spy0312 fhuD; ferrichrome-binding protein K25308 fhuD; ferric hydroxamate/heme transport system substrate-binding protein D M28_Spy0311 fhuB; ferrichrome transport system permease protein K25288 fhuB; ferric hydroxamate/heme transport system permease protein D M28_Spy0310 fhuG; ferrichrome transport system permease protein K25289 fhuG; ferric hydroxamate/heme transport system permease protein D M28_Spy0313 fhuA; ferrichrome transport ATP-binding protein K25290 fhuA; ferric hydroxamate/heme transport system ATP-binding protein [EC:7.2.2.16] D M28_Spy1518 ferrichrome-binding protein K25113 htsA; heme transport system substrate-binding protein D M28_Spy1517 ferrichrome transport system permease protein fhuB K25114 htsB; heme transport system permease protein D M28_Spy1516 fhuC; ferrichrome transport ATP-binding protein K25115 htsC; heme transport system ATP-binding protein [EC:7.6.2.5] D M28_Spy1519 shp; putative heme binding protein K25119 shp; heme transport system cell surface heme-binding protein D M28_Spy1520 putative Fe3+-siderophore transport protein K25120 shr; heme sequestration protein D M28_Spy0521 high-affinity zinc uptake system protein ZnuA precursor K09815 znuA; zinc transport system substrate-binding protein D M28_Spy1696 lmb; laminin binding protein K09815 znuA; zinc transport system substrate-binding protein D M28_Spy0077 adcB; high-affinity zinc uptake system membrane protein K09816 znuB; zinc transport system permease protein D M28_Spy0076 adcC; high-affinity zinc uptake system ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D M28_Spy0357 mtsA; manganese-binding protein K11704 mtsA; iron/zinc/manganese/copper transport system substrate-binding protein D M28_Spy0359 mtsC; manganese transport system membrane protein K11705 mtsC; iron/zinc/manganese/copper transport system permease protein D M28_Spy0358 mtsB; manganese transport system ATP-binding protein K11706 mtsB; iron/zinc/manganese/copper transport system ATP-binding protein D M28_Spy0175 BioY K03523 bioY; biotin transport system substrate-specific component D M28_Spy1513 permease K16926 htsT; energy-coupling factor transport system substrate-specific component D M28_Spy0480 integral membrane protein K16927 cbrT; energy-coupling factor transport system substrate-specific component D M28_Spy1876 cbiQ; cobalt transport protein K16785 ecfT; energy-coupling factor transport system permease protein D M28_Spy1512 cobalt transport protein cbiQ K16785 ecfT; energy-coupling factor transport system permease protein D M28_Spy1878 cbiO1; cobalt transport ATP-binding protein K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D M28_Spy1877 cbiO2; cobalt transport ATP-binding protein K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D M28_Spy1511 cobalt transport ATP-binding protein cbiO K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D M28_Spy0786 srtE; lantibiotic transport permease protein K20491 nisE; lantibiotic transport system permease protein D M28_Spy0787 srtG; lantibiotic transport permease protein K20492 nisG; lantibiotic transport system permease protein D M28_Spy0785 srtF; lantibiotic transport ATP-binding protein K20490 nisF; lantibiotic transport system ATP-binding protein D M28_Spy0548 sagI; streptolysin S export transmembrane protein K25142 lnrN; linearmycin/streptolysin S transport system permease protein D M28_Spy0547 sagH; streptolysin S export transmembrane protein K25143 lnrM; linearmycin/streptolysin S transport system permease protein D M28_Spy0546 sagG; streptolysin S export ATP-binding protein K25144 lnrL; linearmycin/streptolysin S transport system ATP-binding protein D M28_Spy0627 ABC transporter permease protein K24948 yknZ; antimicrobial peptide resistance transport system permease protein D M28_Spy1710 ABC transporter permease protein K24948 yknZ; antimicrobial peptide resistance transport system permease protein D M28_Spy1711 ABC transporter ATP-binding protein K24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-] D M28_Spy0626 ABC transporter ATP-binding protein K24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-] D M28_Spy0511 ftsX; cell division protein K09811 ftsX; cell division transport system permease protein D M28_Spy0510 ftsE; cell division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein D M28_Spy0418 ABC transporter permease protein K25154 evrC; viologen exporter family transport system permease protein D M28_Spy0417 putative transmembrane protein K25155 evrB; viologen exporter family transport system permease protein D M28_Spy0416 putative ABC transporter K25156 evrA; viologen exporter family transport system ATP-binding protein D M28_Spy1459 ecsB; ABC-type exoprotein transporter permease component EcsB K25157 ecsB; ABC-2 type transport system permease protein D M28_Spy1460 ecsA; ABC-type exoprotein transporter ATP-binding protein EcsA K25158 ecsA; ABC-2 type transport system ATP-binding protein D M28_Spy1415 proB; ABC transporter permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein D M28_Spy1506 hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein D M28_Spy0584 rgpCc; polysaccharide export ABC transporter permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein D M28_Spy1416 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D M28_Spy0585 rgpDc; polysaccharide export ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D M28_Spy0964 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D M28_Spy1507 putative ATP transporter K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D M28_Spy1617 salY; ABC transporter permease protein K02004 ABC.CD.P; putative ABC transport system permease protein D M28_Spy0570 ABC transporter permease protein K02004 ABC.CD.P; putative ABC transport system permease protein D M28_Spy0938 ABC transporter permease protein K02004 ABC.CD.P; putative ABC transport system permease protein D M28_Spy1575 putative ABC transporter permease protein K02004 ABC.CD.P; putative ABC transport system permease protein D M28_Spy1618 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D M28_Spy0571 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D M28_Spy0939 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D M28_Spy1574 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D M28_Spy0237 ABC transporter ATP-binding protein K09013 sufC; Fe-S cluster assembly ATP-binding protein D M28_Spy0041 Na+ driven multidrug efflux pump K26937 dinF; MATE family, multidrug efflux pump D M28_Spy1129 oxalate/formate antiporter K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter D M28_Spy0350 phosphoglycerate transporter protein K02445 glpT; MFS transporter, OPA family, glycerol-3-phosphate transporter D M28_Spy0399 multidrug resistance protein B K08161 mdtG; MFS transporter, DHA1 family, multidrug resistance protein D M28_Spy1787 lmrP; multidrug resistance protein B K08152 lmrP; MFS transporter, DHA1 family, multidrug resistance protein B D M28_Spy0454 multidrug resistance protein B K18926 lmrB; MFS transporter, DHA2 family, lincomycin resistance protein D M28_Spy1113 pstI; phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] D M28_Spy1114 ptsH; phosphocarrier protein HPr K02784 ptsH; phosphocarrier protein HPr D M28_Spy1678 PTS system, glucose-specific IIABC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208] D M28_Spy1529 scrA; PTS system, sucrose-specific IIABC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D M28_Spy0456 PTS system, beta-glucoside-specific IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D M28_Spy1768 PTS system, trehalose-specific IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D M28_Spy0643 fruA; PTS system, fructose-specific IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D M28_Spy1624 lacF; PTS system, lactose-specific IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D M28_Spy1623 lacE; PTS system, lactose-specific IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D M28_Spy1733 PTS system, cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D M28_Spy1062 PTS system, cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D M28_Spy1063 PTS system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D M28_Spy1732 PTS system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D M28_Spy1731 PTS system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component D M28_Spy1060 PTS system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component D M28_Spy1444 PTS system, galactose-specific IIA component K20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204] D M28_Spy1443 PTS system, galactose-specific IIB component K20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204] D M28_Spy1442 PTS system, galactose-specific IIC component K20114 gatC; galactose PTS system EIIC component D M28_Spy1468 manL; PTS system, mannose-specific IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D M28_Spy0757 PTS system, mannose/fructose family IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D M28_Spy0759 ptsC; PTS system, mannose/fructose family IIC component K02795 manY; mannose PTS system EIIC component D M28_Spy1469 manM; PTS system, mannose-specific IIC component K02795 manY; mannose PTS system EIIC component D M28_Spy0760 ptsD; PTS system, mannose/fructose family IID component K02796 manZ; mannose PTS system EIID component D M28_Spy1470 manN; PTS system, mannose-specific IID component K02796 manZ; mannose PTS system EIID component D M28_Spy0758 ptsB; PTS system, mannose/fructose family IIB component K19507 gfrB; fructoselysine/glucoselysine PTS system EIIB component [EC:2.7.1.-] D M28_Spy0502 PTS system, N-acetylgalactosamine-specific IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-] D M28_Spy0500 agaV; PTS system, N-acetylgalactosamine-specific IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-] D M28_Spy0499 PTS system, N-acetylgalactosamine-specific IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component D M28_Spy0498 agaD; PTS system, N-acetylgalactosamine-specific IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component D M28_Spy0148 PTS system, 3-keto-L-gulonate specific IIA component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D M28_Spy1652 transcription antiterminator, BglG family K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D M28_Spy0147 PTS system, 3-keto-L-gulonate specific IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D M28_Spy1651 PTS system, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D M28_Spy0146 PTS system, 3-keto-L-gulonate specific IIC component K03475 ulaA; ascorbate PTS system EIIC component D M28_Spy1650 putative transport protein sgaT K03475 ulaA; ascorbate PTS system EIIC component D M28_Spy1422 glpF; glycerol uptake facilitator protein K02440 glpF; glycerol uptake facilitator D M28_Spy1561 glpF.2; aquaporin K02440 glpF; glycerol uptake facilitator D M28_Spy0699 glutathione S-transferase K00799 GST; glutathione S-transferase [EC:2.5.1.18] D M28_Spy1155 formate transporter K21993 fdhC; formate transporter D M28_Spy0577 mscL; large-conductance mechanosensitive channel K03282 mscL; large conductance mechanosensitive channel D M28_Spy1602 mechanosensitive ion channel K22044 ybiO; moderate conductance mechanosensitive channel D M28_Spy1538 corA; magnesium and cobalt transport protein K03284 corA; magnesium transporter D M28_Spy0306 hlyX; putative hemolysin K03699 tlyC; magnesium and cobalt exporter, CNNM family D M28_Spy0781 srtA; lantibiotic K20482 nisA; lantibiotic bacteriocin D M28_Spy0634 czcD; cobalt-zinc-cadmium resistance protein K16264 czcD; cobalt-zinc-cadmium efflux system protein D M28_Spy1889 glucose uptake protein-like protein K05340 glcU; glucose uptake protein D M28_Spy0267 serine/threonine sodium symporter K07862 sstT; serine/threonine transporter D M28_Spy0269 potassium uptake protein KtrB K03498 trkH; trk/ktr system potassium uptake protein D M28_Spy0268 potassium uptake protein KtrA K03499 trkA; trk/ktr system potassium uptake protein D M28_Spy0620 pyrP; uracil permease K02824 uraA; uracil permease D M28_Spy0833 xanthine permease K16169 pbuX; xanthine permease D M28_Spy1466 guanine-hypoxanthine permease K06901 pbuG; adenine/guanine/hypoxanthine permease D M28_Spy0813 chloride channel protein K03281 clcA; chloride channel protein, CIC family D M28_Spy1119 chloride channel protein K03281 clcA; chloride channel protein, CIC family D M28_Spy0528 chloride channel protein K03281 clcA; chloride channel protein, CIC family D M28_Spy1432 sodium-dependent phosphate transporter K03324 yjbB; phosphate:Na+ symporter D M28_Spy1147 kup system potassium uptake protein K03549 kup; KUP system potassium uptake protein D M28_Spy0302 riboflavin transporter K23675 fmnP; riboflavin transporter D M28_Spy0478 thiamine transporter K16789 thiT; thiamine transporter D M28_Spy1156 hypothetical protein K16788 niaX; niacin transporter D M28_Spy0485 ftsW; cell division protein K03588 ftsW; cell division protein FtsW D M28_Spy1702 emm28 protein K03646 tolA; colicin import membrane protein D M28_Spy0870 oxaloacetate decarboxylase beta chain K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D M28_Spy0876 oadB; oxaloacetate decarboxylase beta chain K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D M28_Spy0867 oadA2; oxaloacetate decarboxylase alpha chain K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] D M28_Spy0882 oadA1; oxaloacetate decarboxylase alpha chain K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] D M28_Spy0868 putative membrane associated protein K01573 oadG; oxaloacetate decarboxylase (Na+ extruding) subunit gamma D M28_Spy0869 biotin carboxyl carrier protein of oxaloacetate decarboxylase K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma D M28_Spy0875 biotin carboxyl carrier protein of oxaloacetate decarboxylase K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma D M28_Spy1288 ccdA; cytochrome c-type biogenesis protein K06196 ccdA; cytochrome c-type biogenesis protein D M28_Spy1712 periplasmic component of efflux system K24950 yknX; membrane fusion protein, antimicrobial resistance system D M28_Spy0625 periplasmic component of efflux system K24950 yknX; membrane fusion protein, antimicrobial resistance system D M28_Spy1067 nicotinamide mononucleotide transporter K03811 pnuC; nicotinamide mononucleotide transporter C 02044 Secretion system [BR:spb02044] D M28_Spy1185 integral membrane protein K02221 yggT; YggT family protein D M28_Spy1143 comEA; ComE operon protein 1 K02237 comEA; competence protein ComEA D M28_Spy1535 comEB; ComE operon protein 2 K01493 comEB; dCMP deaminase [EC:3.5.4.12] D M28_Spy1141 comEC.1; ComE operon protein 3 K02238 comEC; competence protein ComEC D M28_Spy1368 comFA; ComF operon protein 1 K02240 comFA; competence protein ComFA D M28_Spy1367 comFC; ComF operon protein 3 K02242 comFC; competence protein ComFC D M28_Spy0084 comYA; competence protein ComYA K02243 comGA; competence protein ComGA D M28_Spy0085 comYB; competence protein ComYB K02244 comGB; competence protein ComGB D M28_Spy0086 comYC; competence protein ComYC K02245 comGC; competence protein ComGC D M28_Spy0087 competence protein ComYD K02246 comGD; competence protein ComGD D M28_Spy0089 comYF; competence protein ComYF K02248 comGF; competence protein ComGF D M28_Spy1199 prepilin peptidase family K02236 comC; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D M28_Spy1524 secA; protein translocase subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D M28_Spy1737 secE; protein translocase subunit K03073 secE; preprotein translocase subunit SecE D M28_Spy0401 secG; protein translocase subunit K03075 secG; preprotein translocase subunit SecG D M28_Spy0063 secY; protein translocase subunit K03076 secY; preprotein translocase subunit SecY D M28_Spy0887 ffh; signal recognition particle, subunit FFH/SRP54 K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D M28_Spy0453 ftsY; cell division protein K03110 ftsY; fused signal recognition particle receptor D M28_Spy1665 yajC; protein translocase subunit K03210 yajC; preprotein translocase subunit YajC D M28_Spy0202 hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D M28_Spy0286 inner membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase C 02042 Bacterial toxins [BR:spb02042] D M28_Spy0337 spyA; C3 family ADP-ribosyltransferase K11044 spyA; C3 family ADP-ribosyltransferase [EC:2.4.2.-] D M28_Spy0700 putative exfoliative toxin K11041 eta; exfoliative toxin A/B D M28_Spy0139 slo; streptolysin O K11031 slo; thiol-activated cytolysin D M28_Spy0306 hlyX; putative hemolysin K03699 tlyC; magnesium and cobalt exporter, CNNM family D M28_Spy0953 cfa; cAMP factor K11045 cfa; cAMP factor D M28_Spy0540 sagA; streptolysin S precursor K11046 sagA; streptolysin S associated protein D M28_Spy0854 conserved membrane protein K11068 hlyIII; hemolysin III D M28_Spy1687 smeZ; mitogenic exotoxin Z K11040 se; staphylococcal enterotoxin D M28_Spy0180 speG; exotoxin type G precursor K11040 se; staphylococcal enterotoxin D M28_Spy0345 speJ; exotoxin type J precursor K11040 se; staphylococcal enterotoxin D M28_Spy0969 speC; pyrogenic exotoxin SpeC K11040 se; staphylococcal enterotoxin D M28_Spy1223 speK; pyrogenic exotoxin SpeK K11040 se; staphylococcal enterotoxin D M28_Spy1355 hyl; hyaluronoglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] C 02022 Two-component system [BR:spb02022] D M28_Spy0424 vicK; two-component sensor histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] D M28_Spy0423 vicR; two-component response regulator K07668 vicR; two-component system, OmpR family, response regulator VicR D M28_Spy0919 ciaH; sensor protein K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3] D M28_Spy0920 ciaR; transcriptional regulatory protein K14983 ciaR; two-component system, OmpR family, response regulator CiaR D M28_Spy0275 covS; CsrS K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3] D M28_Spy0274 covR; TCS DNA-binding response regulator, control of virulence CovR K18941 arlR; two-component system, OmpR family, response regulator ArlR D M28_Spy1708 ihk; two component system histidine kinase K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3] D M28_Spy1709 irr; two-component response regulator K18987 irr; two-component system, OmpR family, response regulator Irr D M28_Spy0780 srtK; sensor protein K20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3] D M28_Spy0779 srtR; two-component response regulator K20488 nisR; two-component system, OmpR family, lantibiotic biosynthesis response regulator NisR/SpaR D M28_Spy1374 yvqE; two-component sensor protein K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3] D M28_Spy1373 yvqC; two-component response regulator K11618 liaR; two-component system, NarL family, response regulator LiaR D M28_Spy1616 sensory transduction protein kinase K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK D M28_Spy1615 salR; transcriptional regulatory protein K14989 salR; two-component system, NarL family, secretion system response regulator SalR D M28_Spy0808 dpiB; sensor kinase K02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3] D M28_Spy0807 dpiA; transcriptional regulatory protein K02475 K02475; two-component system, CitB family, response regulator D M28_Spy1359 rocA; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D M28_Spy0198 fasB; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D M28_Spy0199 fasC; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D M28_Spy0200 fasA; response regulator K07707 agrA; two-component system, LytTR family, response regulator AgrA D M28_Spy1218 yesM; two-component system sensor kinase YesM K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D M28_Spy1347 two-component sensor kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D M28_Spy1346 two-component response regulator K07720 yesN; two-component system, response regulator YesN D M28_Spy0762 two-component response regulator K07720 yesN; two-component system, response regulator YesN D M28_Spy1219 yesN; two-component system response regulator YesN K07720 yesN; two-component system, response regulator YesN C 02035 Bacterial motility proteins [BR:spb02035] D M28_Spy0686 cystine-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D M28_Spy0262 ABC transporter substrate-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:spb04812] D M28_Spy1188 ftsZ; cell division protein K03531 ftsZ; cell division protein FtsZ D M28_Spy1189 ftsA; cell division protein K03590 ftsA; cell division protein FtsA D M28_Spy1899 parB; chromosome partitioning protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D M28_Spy1255 ParB-like protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein C 04147 Exosome [BR:spb04147] D M28_Spy0535 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D M28_Spy0227 plr; glyceraldehyde 3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D M28_Spy1591 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D M28_Spy0960 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D M28_Spy0360 peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D M28_Spy1747 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D M28_Spy1487 dnaK; chaperone protein K04043 dnaK; molecular chaperone DnaK D M28_Spy0183 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D M28_Spy1890 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D M28_Spy0487 protein translation elongation factor Tu (EF-TU) K02358 tuf; elongation factor Tu D M28_Spy1461 hit; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D M28_Spy0847 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D M28_Spy0421 long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D M28_Spy0420 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy1385 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0117 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D M28_Spy0064 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D M28_Spy0708 apt; adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D M28_Spy1424 glpK; glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D M28_Spy1588 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D M28_Spy0027 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D M28_Spy0734 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D M28_Spy0488 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D M28_Spy1158 gpmA; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] C 02048 Prokaryotic defense system [BR:spb02048] D M28_Spy1290 cas1; Type I-C CRISPR associated endonuclease, Cas1 K15342 cas1; CRISP-associated protein Cas1 D M28_Spy0749 cas1; Type II CRISPR associated endonuclease, Cas1 K15342 cas1; CRISP-associated protein Cas1 D M28_Spy0750 cas2; Type II CRISPR associated endonuclease, Cas2 K09951 cas2; CRISPR-associated protein Cas2 D M28_Spy1289 cas2; CRISPR associated endonuclease Cas2 K09951 cas2; CRISPR-associated protein Cas2 D M28_Spy1295 cas3; CRISPR associated helicase-endonuclease Cas3 K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] D M28_Spy1291 cas4; CRISPR associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] D M28_Spy1293 cas8c; Type I-C CRISPR associated protein Cas8c or Csd1 K19117 csd1; CRISPR-associated protein Csd1 D M28_Spy1292 cas7; Type I-C CRISPR associated protein Cas7 or Csd2 K19118 csd2; CRISPR-associated protein Csd2 D M28_Spy1294 cas5; Type I-C CRISPR associated protein Cas5 K19119 cas5d; CRISPR-associated protein Cas5d D M28_Spy0748 cas9; Type II CRISPR RNA-guided endonuclease, Cas9 K09952 csn1; CRISPR-associated endonuclease Csn1 [EC:3.1.-.-] D M28_Spy0751 csn2; Type II CRISPR associated protein, Csn2 K19137 csn2; CRISPR-associated protein Csn2 D M28_Spy1610 hsdR; type I restriction-modification system restriction subunit K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] D M28_Spy1611 hsdS; type I restriction-modification system specificity subunit K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D M28_Spy1612 hsdM; type I restriction-modification system methylation subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D M28_Spy0091 adenine-specific methyltransferase K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] D M28_Spy0774 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D M28_Spy1840 RelE-domain protein K06218 relE; mRNA interferase RelE/StbE D M28_Spy1841 hypothetical protein K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB D M28_Spy1334 hypothetical protein K07473 dinJ; DNA-damage-inducible protein J D M28_Spy0444 relB; toxin-antitoxin stabilization system antitoxin protein RelB K07473 dinJ; DNA-damage-inducible protein J D M28_Spy0445 relE; toxin-antitoxin stabilization system toxin protein RelE K19092 parE1_3_4; toxin ParE1/3/4 D M28_Spy0778 srtI; SrtI K21498 higA-1; antitoxin HigA-1 D M28_Spy1188 ftsZ; cell division protein K03531 ftsZ; cell division protein FtsZ D M28_Spy0692 parC; topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D M28_Spy0691 parE; topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D M28_Spy0610 nifS1; cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D M28_Spy0820 nifS2; cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels [BR:spb04040] C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules [BR:spb04090] C 01504 Antimicrobial resistance genes [BR:spb01504] D M28_Spy1491 D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D M28_Spy1054 dltA; D-alanine-activating enzyme K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D M28_Spy1053 DltB K03739 dltB; membrane protein involved in D-alanine export D M28_Spy1052 D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D M28_Spy1051 dltD; protein precursor K03740 dltD; D-alanine transfer protein C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins [BR:spb00536] D M28_Spy1355 hyl; hyaluronoglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:spb00537] D M28_Spy1355 hyl; hyaluronoglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] D M28_Spy0137 nga; NAD glycohydrolase K18153 nga; NAD+ glycohydrolase [EC:3.2.2.5] C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:spb03100] D M28_SpyT0001 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D M28_SpyT0011 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D M28_SpyT0029 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D M28_SpyT0042 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D M28_SpyT0057 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D M28_SpyT0062 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D M28_SpyT0048 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D M28_SpyT0067 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D M28_SpyT0045 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D M28_SpyT0009 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D M28_SpyT0019 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D M28_SpyT0060 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D M28_SpyT0044 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D M28_SpyT0065 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D M28_SpyT0061 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D M28_SpyT0043 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D M28_SpyT0003 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D M28_SpyT0013 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D M28_SpyT0055 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D M28_SpyT0064 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D M28_SpyT0047 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D M28_SpyT0040 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D M28_SpyT0033 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D M28_SpyT0066 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D M28_SpyT0050 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D M28_SpyT0026 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D M28_SpyT0031 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D M28_SpyT0007 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D M28_SpyT0017 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D M28_SpyT0039 tRNA-His K14226 tRNA-His; tRNA His D M28_SpyT0027 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D M28_SpyT0051 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D M28_SpyT0032 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D M28_SpyT0008 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D M28_SpyT0018 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D M28_SpyT0041 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D M28_SpyT0005 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D M28_SpyT0053 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D M28_SpyT0015 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D M28_SpyT0059 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D M28_SpyT0004 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D M28_SpyT0014 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D M28_SpyT0054 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D M28_SpyT0063 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D M28_SpyT0021 tRNA-Met K14230 tRNA-Met; tRNA Met D M28_SpyT0022 tRNA-Met K14230 tRNA-Met; tRNA Met D M28_SpyT0024 tRNA-Met K14230 tRNA-Met; tRNA Met D M28_SpyT0035 tRNA-Met K14230 tRNA-Met; tRNA Met D M28_SpyT0025 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D M28_SpyT0036 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D M28_SpyT0010 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D M28_SpyT0020 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D M28_SpyT0058 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D M28_SpyT0028 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D M28_SpyT0023 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D M28_SpyT0034 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D M28_SpyT0049 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D M28_SpyT0006 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D M28_SpyT0052 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D M28_SpyT0016 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D M28_SpyT0038 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D M28_SpyT0037 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D M28_SpyT0046 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D M28_SpyT0002 tRNA-Val K14237 tRNA-Val; tRNA Val D M28_SpyT0030 tRNA-Val K14237 tRNA-Val; tRNA Val D M28_SpyT0012 tRNA-Val K14237 tRNA-Val; tRNA Val D M28_SpyT0056 tRNA-Val K14237 tRNA-Val; tRNA Val D M28_SpyR0018 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0015 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0001 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0010 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0004 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0007 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D M28_SpyR0002 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0008 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0011 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0005 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0017 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0014 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D M28_SpyR0003 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_SpyR0012 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_SpyR0006 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_SpyR0009 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_SpyR0013 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_SpyR0016 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D M28_Spytm01 M28_Spytm01 K15035 ssrA; transfer-messenger RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D M28_Spy0503 idnO; gluconate 5-dehydrogenase K00046 idnO; gluconate 5-dehydrogenase [EC:1.1.1.69] D M28_Spy0328 lctO; L-lactate oxidase K10530 lctO; L-lactate oxidase [EC:1.1.3.2] D M28_Spy1753 ahpF; peroxiredoxin reductase (NAD(P)H) K03387 ahpF; NADH-dependent peroxiredoxin subunit F [EC:1.8.1.-] D M28_Spy0368 msrA.2; peptide methionine sulfoxide reductase K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] D M28_Spy1286 msrA; peptide methionine sulfoxide reductase K12267 msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12] D M28_Spy0755 msrB; peptide methionine sulfoxide reductase K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] D M28_Spy1752 ahpC; peroxiredoxin reductase (NAD(P)H) K24119 ahpC; NADH-dependent peroxiredoxin subunit C [EC:1.11.1.26] D M28_Spy0638 trxB; thioredoxin reductase K21567 fnr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] D M28_Spy0677 arsC; arsenate reductase family protein K00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1] D M28_Spy1773 nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein K04068 nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4] D M28_Spy0307 pflC; pyruvate formate-lyase activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D M28_Spy1736 pyruvate formate-lyase activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D M28_Spy1392 methyltransferase K07444 ypsC; putative N6-adenine-specific DNA methylase [EC:2.1.1.-] D M28_Spy0404 glutaminyl-peptide cyclotransferase K22757 QCT; glutaminyl-peptide cyclotransferase [EC:2.3.2.5] D M28_Spy0435 glycosyltransferase K21349 ggs; glucosylglycerate synthase [EC:2.4.1.268] D M28_Spy0466 lgt; prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145] D M28_Spy0834 apbE; thiamine biosynthesis lipoprotein K03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180] D M28_Spy1594 putative kinase K07030 fakA; fatty acid kinase [EC:2.7.2.18] D M28_Spy0740 putative membrane spanning protein K18672 dacA; diadenylate cyclase [EC:2.7.7.85] D M28_Spy0465 ptsK; hpr(ser) kinase K06023 hprK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-] D M28_Spy0727 estA; acetyl esterase K03930 estA; putative tributyrin esterase [EC:3.1.1.-] D M28_Spy0252 putative lipase K07015 yqeG; putative phosphatase [EC:3.1.3.-] D M28_Spy1869 phosphoesterase, DHH family protein K22927 gdpP; cyclic-di-AMP phosphodiesterase [EC:3.1.4.59] D M28_Spy0214 tatD; sec-independent protein translocase protein K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D M28_Spy0215 ribonuclease M5 K05985 rnmV; ribonuclease M5 [EC:3.1.26.8] D M28_Spy1669 dexB; glucan 1,6-alpha-glucosidase K01215 dexB; glucan 1,6-alpha-glucosidase [EC:3.2.1.70] D M28_Spy0501 unsaturated glucuronyl hydrolase K18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180] D M28_Spy0242 D-alanyl-D-alanine carboxypeptidase K01286 E3.4.16.4; D-alanyl-D-alanine carboxypeptidase [EC:3.4.16.4] D M28_Spy1672 ska; streptokinase K14745 ska; streptokinase A [EC:3.4.-.-] D M28_Spy1657 def; peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D M28_Spy0657 fms; peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D M28_Spy1111 peptidoglycan N-acetylglucosamine deacetylase K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104] D M28_Spy0121 translation initiation inhibitor K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10] D M28_Spy0371 67 kDa myosin-crossreactive antigen K10254 ohyA; oleate hydratase [EC:4.2.1.53] D M28_Spy0736 hylA; hyaluronate lyase precursor K01727 hysA; hyaluronate lyase [EC:4.2.2.1] D M28_Spy0495 pacL; calcium-transporting ATPase K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10] D M28_Spy1161 lead, cadmium, zinc and mercury transporting ATPase K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21] C 99981 Carbohydrate metabolism C 99982 Energy metabolism D M28_Spy0595 ferredoxin K05337 fer; ferredoxin D M28_Spy0240 nifU; IscU K04488 iscU; nitrogen fixation protein NifU and related proteins C 99983 Lipid metabolism D M28_Spy0652 degV family protein K25232 fakB; fatty acid kinase fatty acid binding subunit D M28_Spy1165 DegV family protein K25232 fakB; fatty acid kinase fatty acid binding subunit C 99984 Nucleotide metabolism D M28_Spy1676 NrdI.1 K03647 nrdI; protein involved in ribonucleotide reduction D M28_Spy0335 nrdI; nrdI K03647 nrdI; protein involved in ribonucleotide reduction D M28_Spy1725 mf; mitogenic factor K15051 endA; DNA-entry nuclease D M28_Spy0564 DNA-entry nuclease K15051 endA; DNA-entry nuclease D M28_Spy0565 endA; DNA-entry nuclease K15051 endA; DNA-entry nuclease D M28_Spy0968 spd1; phage DNase Spd1 K15051 endA; DNA-entry nuclease C 99985 Amino acid metabolism D M28_Spy0850 lactoylglutathione lyase K08234 yaeR; glyoxylase I family protein D M28_Spy1187 pyridoxal-5'-phosphate family protein K06997 yggS; PLP dependent protein C 99986 Glycan metabolism C 99987 Cofactor metabolism C 99988 Secondary metabolism C 99999 Others B B 09192 Unclassified: genetic information processing C 99973 Transcription D M28_Spy1751 csp; cold shock protein K03704 cspA; cold shock protein D M28_Spy1280 phage antirepressor protein K07741 antB; anti-repressor protein D M28_Spy0932 arsenate reductase family protein K16509 spxA; regulatory protein spx D M28_Spy1782 arsenate reductase family protein K16509 spxA; regulatory protein spx D M28_Spy0461 transcription accessory protein K06959 tex; protein Tex C 99974 Translation D M28_Spy1371 s1-type RNA-binding domain K07570 GSP13; general stress protein 13 C 99975 Protein processing D M28_Spy1601 ropA; trigger factor, ppiase K03545 tig; trigger factor D M28_Spy0403 ssrA-binding protein K03664 smpB; SsrA-binding protein D M28_Spy1115 nrdH; glutaredoxin K06191 nrdH; glutaredoxin-like protein NrdH D M28_Spy0234 mecA; negative regulator of genetic competence K16511 mecA1_2; adapter protein MecA 1/2 C 99976 Replication and repair D M28_Spy0816 radC; DNA repair protein K03630 radC; DNA repair protein RadC D M28_Spy0220 rmuC family protein K09760 rmuC; DNA recombination protein RmuC D M28_Spy1146 hypothetical protein K07461 K07461; putative endonuclease D M28_Spy0858 smf; smf K04096 smf; DNA processing protein D M28_Spy0709 dnaD; phage protein K02086 dnaD; DNA replication protein D M28_Spy1274 DnaD-like protein K02086 dnaD; DNA replication protein D M28_Spy1321 transcriptional regulator, Cro/CI family K07467 nicK; putative DNA relaxase D M28_Spy0998 phage terminase small subunit K07474 xtmA; phage terminase small subunit D M28_Spy0997 terminase large subunit K06909 xtmB; phage terminase large subunit D M28_Spy1684 ATPase, AAA family K07478 ycaJ; putative ATPase D M28_Spy1896 transposase K07482 K07482; transposase, IS30 family D M28_Spy1071 transposase K07483 K07483; transposase D M28_Spy0170 transposase K07483 K07483; transposase D M28_Spy0166 transposase K07483 K07483; transposase D M28_Spy0449 transposase K07483 K07483; transposase D M28_Spy0536 transposase K07486 K07486; transposase D M28_Spy0382 transposase K07493 K07493; putative transposase D M28_Spy1072 transposase K07497 K07497; putative transposase D M28_Spy0448 transposase K07497 K07497; putative transposase D M28_Spy0169 transposase K07497 K07497; putative transposase C 99979 Viral proteins C 99998 Others D M28_Spy1568 putative cytosolic protein K09747 ebfC; nucleoid-associated protein EbfC B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D M28_Spy1400 amino acid permease K03293 TC.AAT; amino acid transporter, AAT family D M28_Spy0014 amino acid permease K03294 TC.APA; basic amino acid/polyamine antiporter, APA family D M28_Spy0873 Mg2+/citrate complex secondary transporter K03300 TC.CITMHS; citrate-Mg2+:H+ or citrate-Ca2+:H+ symporter, CitMHS family D M28_Spy0950 Na(+)-linked D-alanine glycine permease K03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family D M28_Spy0266 braB; branched-chain amino acid transport system carrier protein K03311 TC.LIVCS; branched-chain amino acid:cation transporter, LIVCS family D M28_Spy1579 nupC; nucleoside permease K03317 TC.CNT; concentrative nucleoside transporter, CNT family C 99978 Cell growth D M28_Spy1391 hypothetical protein K20073 mapZ; mid-cell-anchored protein Z D M28_Spy0203 Jag protein K06346 jag; spoIIIJ-associated protein D M28_Spy1079 site-specific recombinase K06400 spoIVCA; site-specific DNA recombinase C 99993 Cell motility C 99995 Signaling proteins D M28_Spy1194 typA; GTP-binding protein TypA/BipA K06207 typA; GTP-binding protein D M28_Spy0372 phoH; PhoH K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins C 99992 Structural proteins D M28_Spy0479 N-acetylmuramoyl-L-alanine amidase K07273 acm; lysozyme C 99994 Others D M28_Spy0923 phoU; phosphate transport system protein K02039 phoU; phosphate transport system protein D M28_Spy0325 cutC; copper homeostasis protein K06201 cutC; copper homeostasis protein B B 09194 Poorly characterized C 99996 General function prediction only D M28_Spy1775 putative oxidoreductase K03810 mviM; virulence factor D M28_Spy1131 putative competence protein/transcription factor K06198 coiA; competence protein CoiA D M28_Spy0099 tRNA binding domain protein K06878 K06878; tRNA-binding protein D M28_Spy0475 hydrolase (HAD superfamily) K07025 K07025; putative hydrolase of the HAD superfamily D M28_Spy0241 ABC transporter-associated protein K09014 sufB; Fe-S cluster assembly protein SufB D M28_Spy0238 ABC transporter-associated protein K09015 sufD; Fe-S cluster assembly protein SufD D M28_Spy1094 ribonuclease BN K07058 K07058; membrane protein D M28_Spy0697 rhodanese-related sulfurtransferase K07146 K07146; UPF0176 protein D M28_Spy0271 lemA; lemA K03744 lemA; LemA protein D M28_Spy0463 zinc metalloprotease K03095 sprL; SprT-like protein D M28_Spy1838 phage protein K01421 yhgE; putative membrane protein D M28_Spy1832 integral membrane protein K08974 K08974; putative membrane protein D M28_Spy0458 putative membrane spanning protein K08986 ycgQ; putative membrane protein D M28_Spy0957 phnA; alkylphosphonate utilization operon functionally uncharacterized protein PhnA K06193 phnA; protein PhnA C 99997 Function unknown D M28_Spy0493 dGTP triphosphohydrolase K06885 K06885; uncharacterized protein D M28_Spy1598 alpha/beta hydrolase K06889 K06889; uncharacterized protein D M28_Spy0290 integral membrane protein K06890 K06890; uncharacterized protein D M28_Spy0158 CoA binding protein K06929 K06929; uncharacterized protein D M28_Spy0289 hydrolase (HAD superfamily) K06950 K06950; uncharacterized protein D M28_Spy0630 RNA binding protein K06960 K06960; uncharacterized protein D M28_Spy1639 putative cytosolic protein K06962 K06962; uncharacterized protein D M28_Spy0549 endonuclease/exonuclease/phosphatase family protein K07004 K07004; uncharacterized protein D M28_Spy0633 putative cytosolic protein K07006 K07006; uncharacterized protein D M28_Spy0862 regulatory protein K07035 K07035; uncharacterized protein D M28_Spy0639 regulatory protein K07035 K07035; uncharacterized protein D M28_Spy0572 neutral zinc metallopeptidase family K07054 K07054; uncharacterized protein D M28_Spy0459 putative membrane spanning protein K07089 K07089; uncharacterized protein D M28_Spy0294 putative phosphoesterase K07095 K07095; uncharacterized protein D M28_Spy1157 transcriptional regulator, biotin repressor family K07105 K07105; uncharacterized protein D M28_Spy0706 short chain dehydrogenase K07124 K07124; uncharacterized protein D M28_Spy0304 Fe-S oxidoreductase K07139 K07139; uncharacterized protein D M28_Spy0300 putative cytosolic protein K08998 K08998; uncharacterized protein D M28_Spy1357 hypothetical protein K09704 K09704; uncharacterized protein D M28_Spy0888 ylxM; signal recognition particle associated protein K09787 K09787; uncharacterized protein D M28_Spy0367 s1 RNA binding domain K00243 K00243; uncharacterized protein D M28_Spy1772 yaaA; peroxide stress protein YaaA K09861 K09861; uncharacterized protein D M28_Spy1065 outer surface protein K09963 K09963; uncharacterized protein D M28_Spy0291 putative exported protein K09976 K09976; uncharacterized protein D M28_Spy0614 putative ribosome-associated protein K07584 ysxB; uncharacterized protein D M28_Spy1362 putative cytosolic protein K07586 ygaC; uncharacterized protein D M28_Spy1454 putative cytosolic protein K07742 ylxR; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: May 12, 2024