+D GENES KO #

  KEGG Orthology (KO) - Streptococcus pyogenes Manfredo (serotype M5)

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A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:spf00010] D SpyM50595 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] D SpyM50167 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D SpyM50812 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D SpyM50246 fba; fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D SpyM51354 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D SpyM50212 plr; glyceraldehyde-3-phosphate dehydrogenase,plasmin receptor K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D SpyM50252 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D SpyM50696 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D SpyM51248 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D SpyM50813 pyk; putative pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D SpyM51008 pdhA; putative pyruvate dehydrogenase E1 component,alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D SpyM51007 pdhB; putative pyruvate dehydrogenase E1 component,beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D SpyM51006 pdhC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SpyM50917 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D SpyM50039 adhE; aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase] K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D SpyM50040 adhP; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D SpyM50618 putative phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D SpyM50860 pgmA; putative phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D SpyM50741 gapN; putative NADP-dependent glyceraldehyde-3-phosphate dehydrogenase K00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9] D SpyM51384 bglA; 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D SpyM50780 putative beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D SpyM50542 putative beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] C 00020 Citrate cycle (TCA cycle) [PATH:spf00020] D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SpyM51008 pdhA; putative pyruvate dehydrogenase E1 component,alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D SpyM51007 pdhB; putative pyruvate dehydrogenase E1 component,beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D SpyM51006 pdhC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] C 00030 Pentose phosphate pathway [PATH:spf00030] D SpyM50167 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D SpyM50203 rpe; putative ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D SpyM50415 tkt; putative transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D SpyM51634 putative transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D SpyM50414 probable transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D SpyM51113 rpiA; ribose 5-phosphate isomerase A K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D SpyM50265 deoC; deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4] D SpyM51112 deoB; phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7] D SpyM50618 putative phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D SpyM50860 pgmA; putative phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D SpyM50016 prsA1; ribose-phosphate pyrophosphokinase 1 K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D SpyM50943 prsA2; putative ribose-phosphate pyrophosphokinase 2 K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D SpyM51336 kgdA; putative KHG/KDPG aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase] K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] D SpyM50741 gapN; putative NADP-dependent glyceraldehyde-3-phosphate dehydrogenase K00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9] D SpyM51337 PfkB family carbohydrate kinase K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45] D SpyM50246 fba; fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D SpyM50812 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] C 00040 Pentose and glucuronate interconversions [PATH:spf00040] D SpyM51825 hasB; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D SpyM51415 putative UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D SpyM51826 hasC1; UTP--glucose-1-phosphate uridylyltransferase 1 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D SpyM50172 hasC2; UTP--glucose-1-phosphate uridylyltransferase 2 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D SpyM50145 putative hexulose-6-phosphate synthase K03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85] D SpyM50146 putative hexulose-6-phosphate isomerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22] D SpyM50147 L-ribulose 5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4] D SpyM50203 rpe; putative ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] C 00051 Fructose and mannose metabolism [PATH:spf00051] D SpyM50310 scrK; fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D SpyM50311 pmi; mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D SpyM50812 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D SpyM51147 fruK; putative 1-phosphofructokinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56] D SpyM50246 fba; fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D SpyM51354 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D SpyM51146 fruA; putative fructose-specific phosphotransferase system (PTS), IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D SpyM50986 sugar phosphotransferase system (PTS),mannose/fructose family, IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D SpyM50366 manL; putative mannose-specific phosphotransferase system (PTS), IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D SpyM50365 manM; putative mannose-specific phosphotransferase system (PTS), IIC component K02795 manY; mannose PTS system EIIC component D SpyM50984 sugar phosphotransferase system (PTS),mannose/fructose family, IIC component K02795 manY; mannose PTS system EIIC component D SpyM50364 manN; putative mannose-specific phosphotransferase system (PTS), IID component K02796 manZ; mannose PTS system EIID component D SpyM50983 sugar phosphotransferase system (PTS),mannose/fructose family, IID component K02796 manZ; mannose PTS system EIID component C 00052 Galactose metabolism [PATH:spf00052] D SpyM51826 hasC1; UTP--glucose-1-phosphate uridylyltransferase 1 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D SpyM50172 hasC2; UTP--glucose-1-phosphate uridylyltransferase 2 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D SpyM50618 putative phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D SpyM50860 pgmA; putative phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D SpyM50595 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] D SpyM50551 glycosyl hydrolase family 2 protein K01190 lacZ; beta-galactosidase [EC:3.2.1.23] D SpyM51611 lacC2; tagatose-6-phosphate kinase 2 K00917 lacC; tagatose 6-phosphate kinase [EC:2.7.1.144] D SpyM50812 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D SpyM50395 lacD1; tagatose 1,6-diphosphate aldolase 1 K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40] D SpyM51610 lacD2; tagatose 1,6-diphosphate aldolase 2 K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40] D SpyM51612 lacB2; galactose-6-phosphate isomerase LacB subunit 2 K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26] D SpyM51613 lacA2; galactose-6-phosphate isomerase LacA subunit 2 K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26] D SpyM50392 lacA1; galactose-6-phosphate isomerase LacA subunit 1 K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26] D SpyM50393 lacB1; galactose-6-phosphate isomerase LacB subunit 1 K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26] D SpyM51607 lacG; 6-phospho-beta-galactosidase K01220 E3.2.1.85; 6-phospho-beta-galactosidase [EC:3.2.1.85] D SpyM51609 lacF; putative lactose-specific phosphotransferase system (PTS), IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D SpyM51608 lacE; putative lactose-specific phosphotransferase system (PTS), IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D SpyM50307 scrB; putative sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D SpyM51340 putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-] D SpyM51342 agaV; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-] D SpyM51343 agaW; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component D SpyM51344 agaD; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component D SpyM51259 agaS; putative tagatose-6-phosphate aldose/ketose isomerase K02082 agaS; D-galactosamine 6-phosphate deaminase/isomerase [EC:3.5.99.-] C 00053 Ascorbate and aldarate metabolism [PATH:spf00053] D SpyM51825 hasB; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D SpyM51415 putative UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D SpyM50144 sugar phosphotransferase system (PTS), IIA component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D SpyM51637 putative PTS multi-domain regulator K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D SpyM50143 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D SpyM51636 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D SpyM51635 putative sugar-specific permease K03475 ulaA; ascorbate PTS system EIIC component D SpyM50142 putative sugar-specific permease, SgaT/UlaA family K03475 ulaA; ascorbate PTS system EIIC component D SpyM50149 conserved hypothetical protein K03476 ulaG; L-ascorbate 6-phosphate lactonase [EC:3.1.1.-] D SpyM50145 putative hexulose-6-phosphate synthase K03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85] D SpyM50146 putative hexulose-6-phosphate isomerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22] D SpyM50147 L-ribulose 5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4] C 00500 Starch and sucrose metabolism [PATH:spf00500] D SpyM50308 scrA; putative sucrose-specific phosphotransferase system (PTS), IIABC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D SpyM50307 scrB; putative sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D SpyM51826 hasC1; UTP--glucose-1-phosphate uridylyltransferase 1 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D SpyM50172 hasC2; UTP--glucose-1-phosphate uridylyltransferase 2 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D SpyM50784 putative lactose/cellobiose-specific phosphotransferase system (PTS), IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D SpyM51709 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D SpyM50783 putative lactose/cellobiose-specific phosphotransferase system (PTS), IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D SpyM51708 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D SpyM51707 sugar phosphotransferase system (PTS), IIC component K02761 celB; cellobiose PTS system EIIC component D SpyM50786 sugar phosphotransferase system (PTS), IIC component K02761 celB; cellobiose PTS system EIIC component D SpyM51384 bglA; 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D SpyM50780 putative beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D SpyM50542 putative beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D SpyM50805 glgP; putative glycogen phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1] D SpyM50804 malM; putative 4-alpha-glucanotransferase K00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25] D SpyM51662 putative glucose-specific phosphotransferase system (PTS), IIABC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208] D SpyM51661 endonuclease/exonuclease/phosphatase family protein K06896 mapP; maltose 6'-phosphate phosphatase [EC:3.1.3.90] D SpyM51743 sugar phosphotransferase system (PTS), IIABC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D SpyM51742 treA; putative trehalose-6-phosphate hydrolase K01226 treC; trehalose-6-phosphate hydrolase [EC:3.2.1.93] D SpyM50618 putative phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D SpyM50860 pgmA; putative phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D SpyM50595 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] D SpyM50167 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D SpyM50310 scrK; fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:spf00520] D SpyM50402 putative N-acetylglucosamine-6-phosphate deacetylase K01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25] D SpyM50718 nagB; glucosamine-6-phosphate isomerase K02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6] D SpyM50310 scrK; fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D SpyM50815 glmS; glucosamine--fructose-6-phosphate aminotransferase [isomerizing] K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D SpyM50996 putative phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10] D SpyM51503 gcaD; bifunctional GlmU protein [includes: UDP-N-acetylglucosamine pyrophosphorylase; glucosamine-1-phosphate N-acetyltransferase] K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D SpyM51224 murA1; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D SpyM50752 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D SpyM50963 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D SpyM50191 putative N-acetylmannosamine-6-phosphate 2-epimerase K01788 nanE; N-acylglucosamine-6-phosphate 2-epimerase [EC:5.1.3.9] D SpyM50196 nanH; putative N-acetylneuraminate lyase K01639 E4.1.3.3; N-acetylneuraminate lyase [EC:4.1.3.3] D SpyM50595 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] D SpyM50618 putative phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D SpyM50860 pgmA; putative phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D SpyM51826 hasC1; UTP--glucose-1-phosphate uridylyltransferase 1 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D SpyM50172 hasC2; UTP--glucose-1-phosphate uridylyltransferase 2 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D SpyM51825 hasB; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D SpyM51415 putative UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D SpyM50986 sugar phosphotransferase system (PTS),mannose/fructose family, IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D SpyM50366 manL; putative mannose-specific phosphotransferase system (PTS), IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D SpyM50365 manM; putative mannose-specific phosphotransferase system (PTS), IIC component K02795 manY; mannose PTS system EIIC component D SpyM50984 sugar phosphotransferase system (PTS),mannose/fructose family, IIC component K02795 manY; mannose PTS system EIIC component D SpyM50364 manN; putative mannose-specific phosphotransferase system (PTS), IID component K02796 manZ; mannose PTS system EIID component D SpyM50983 sugar phosphotransferase system (PTS),mannose/fructose family, IID component K02796 manZ; mannose PTS system EIID component D SpyM50167 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D SpyM50311 pmi; mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] C 00620 Pyruvate metabolism [PATH:spf00620] D SpyM51008 pdhA; putative pyruvate dehydrogenase E1 component,alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D SpyM51007 pdhB; putative pyruvate dehydrogenase E1 component,beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D SpyM51006 pdhC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SpyM50281 pfl; formate acetyltransferase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D SpyM50039 adhE; aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase] K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D SpyM50040 adhP; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D SpyM50092 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D SpyM50938 pta; putative phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D SpyM50813 pyk; putative pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D SpyM50361 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D SpyM50357 fabE; biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D SpyM50359 accC; biotin carboxylase subunit of acetyl-CoA carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D SpyM50360 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D SpyM51560 putative acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D SpyM50917 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D SpyM51449 gloA; putative lactoylglutathione lyase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5] D SpyM51330 metallo-beta-lactamase superfamily protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D SpyM50955 NAD-dependent malic enzyme K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D SpyM50888 putative carboxylase subunit K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] D SpyM50903 putative carboxylase subunit K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] D SpyM50900 putative glutaconyl-CoA decarboxylase beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D SpyM50894 putative Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D SpyM50902 putative membrane protein K01573 oadG; oxaloacetate decarboxylase (Na+ extruding) subunit gamma D SpyM51358 ppc; putative phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:spf00630] D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM50255 glnA; putative glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D SpyM50923 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SpyM51596 putative glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D SpyM51336 kgdA; putative KHG/KDPG aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase] K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] C 00640 Propanoate metabolism [PATH:spf00640] D SpyM50092 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D SpyM50938 pta; putative phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SpyM50281 pfl; formate acetyltransferase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D SpyM50361 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D SpyM50357 fabE; biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D SpyM50359 accC; biotin carboxylase subunit of acetyl-CoA carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D SpyM50360 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D SpyM50917 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D SpyM51704 gldA; glycerol dehydrogenase K00005 gldA; glycerol dehydrogenase [EC:1.1.1.6] C 00650 Butanoate metabolism [PATH:spf00650] D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM50115 atoD1; acetate CoA-transferase alpha subunit 1 K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D SpyM50446 atoD2; acetate CoA-transferase alpha subunit 2 K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D SpyM50116 atoA1; acetate CoA-transferase beta subunit 1 K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] D SpyM50039 adhE; aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase] K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D SpyM50900 putative glutaconyl-CoA decarboxylase beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D SpyM50894 putative Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D SpyM50901 putative glutaconyl-CoA decarboxylase gamma subunit K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma D SpyM50895 putative decarboxylase gamma chain K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma D SpyM50979 putative succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D SpyM50281 pfl; formate acetyltransferase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D SpyM51121 mvaS; 3-hydroxy-3-methylglutaryl coenzyme A synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D SpyM50444 putative D-beta-hydroxybutyrate dehydrogenase K00019 BDH1; 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30] D SpyM50954 putative zinc-binding alcohol dehydrogenase K18369 adh2; alcohol dehydrogenase [EC:1.1.1.-] D SpyM51329 putative acetoin reductase K03366 butA; meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304] C 00660 C5-Branched dibasic acid metabolism C 00562 Inositol phosphate metabolism [PATH:spf00562] D SpyM50841 putative myo-inositol-1(or 4)-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D SpyM51505 conserved hypothetical protein K22230 iolU; scyllo-inositol 2-dehydrogenase (NADP+) [EC:1.1.1.-] D SpyM51354 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:spf00190] D SpyM51229 atpA; ATP synthase alpha chain K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D SpyM51227 atpD; ATP synthase beta chain K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D SpyM51228 atpG; ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D SpyM51230 atpH; putative ATP synthase delta chain K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D SpyM51226 atpC; ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D SpyM51232 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a D SpyM51231 atpF; ATP synthase B chain K02109 ATPF0B; F-type H+-transporting ATPase subunit b D SpyM51233 atpE; ATP synthase C chain K02110 ATPF0C; F-type H+-transporting ATPase subunit c D SpyM50126 ntpA; V-type sodium ATP synthase subunit A K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1] D SpyM50127 ntpB; V-type sodium ATP synthase subunit B K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B D SpyM50124 ntpC; V-type sodium ATP synthase subunit C K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C D SpyM50128 ntpD; V-type sodium ATP synthase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D D SpyM50123 ntpE; V-type sodium ATP synthase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E D SpyM50125 V-type sodium ATP synthase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F D SpyM50120 hypothetical protein K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H D SpyM50121 ntpI; V-type sodium ATP synthase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I D SpyM50122 ntpK; V-type sodium ATP synthase subunit K K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K D SpyM51539 ppaC; manganese-dependent inorganic pyrophosphatase K15986 ppaC; manganese-dependent inorganic pyrophosphatase [EC:3.6.1.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation in photosynthetic organisms C 00720 Carbon fixation pathways in prokaryotes C 00680 Methane metabolism [PATH:spf00680] D SpyM50923 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D SpyM51248 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D SpyM51358 ppc; putative phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D SpyM50246 fba; fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D SpyM50812 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D SpyM50092 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D SpyM50938 pta; putative phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D SpyM50696 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D SpyM51421 conserved hypothetical protein K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34] C 00910 Nitrogen metabolism [PATH:spf00910] D SpyM50255 glnA; putative glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D SpyM50582 arcC; carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] D SpyM50180 putative carbonic anhydrase K01673 cynT; carbonic anhydrase [EC:4.2.1.1] C 00920 Sulfur metabolism [PATH:spf00920] D SpyM51257 conserved hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] D SpyM51631 cysE; serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D SpyM50462 cysM; putative cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis [PATH:spf00061] D SpyM50361 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D SpyM50357 fabE; biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D SpyM50359 accC; biotin carboxylase subunit of acetyl-CoA carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D SpyM50360 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D SpyM50019 putative acyl carrier protein K02078 acpP; acyl carrier protein D SpyM50352 acpP; acyl carrier protein (ACP) K02078 acpP; acyl carrier protein D SpyM50354 fabD; putative malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D SpyM50351 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D SpyM50356 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D SpyM51506 putative short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SpyM50355 fabG; 3-oxoacyl-[acyl-carrier protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SpyM50358 fabZ; (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D SpyM50353 fabK; enoyl-ACP reductase K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9] D SpyM50349 enoyl-CoA hydratase/isomerase family protein K18474 fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14] D SpyM51431 hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 00062 Fatty acid elongation C 00071 Fatty acid degradation [PATH:spf00071] D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM51431 hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D SpyM50039 adhE; aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase] K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D SpyM50040 adhP; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism [PATH:spf00561] D SpyM51596 putative glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D SpyM51437 dihydroxyacetone kinase family protein K05878 dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121] D SpyM51436 dihydroxyacetone kinase family protein K05879 dhaL; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaL [EC:2.7.1.121] D SpyM51435 sugar phosphotransferase system (PTS), fructose family, IIA component K05881 dhaM; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaM [EC:2.7.1.121] D SpyM51704 gldA; glycerol dehydrogenase K00005 gldA; glycerol dehydrogenase [EC:1.1.1.6] D SpyM50409 glpK; glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D SpyM50018 plsX; fatty acid/phospholipid synthesis protein K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D SpyM51098 putative membrane protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D SpyM50710 putative acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D SpyM51234 conserved hypothetical protein K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107] D SpyM51444 putative glycosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D SpyM51445 putative glycosyltransferase K13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208] D SpyM51185 putative sulfatase K19005 ltaS; lipoteichoic acid synthase [EC:2.7.8.20] C 00564 Glycerophospholipid metabolism [PATH:spf00564] D SpyM50173 gpsA; glycerol-3-phosphate dehydrogenase [NAD(P)+] K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] D SpyM50410 glpO; alpha-glycerophosphate oxidase K00105 E1.1.3.21; alpha-glycerophosphate oxidase [EC:1.1.3.21] D SpyM51098 putative membrane protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D SpyM50710 putative acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D SpyM51234 conserved hypothetical protein K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107] D SpyM51160 putative glycerophosphodiester phosphodiesterase K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] D SpyM51647 putative phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41] D SpyM51819 pgsA; putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5] D SpyM50290 putative PAP2 superfamily protein K01096 pgpB; phosphatidylglycerophosphatase B [EC:3.1.3.27 3.6.1.75 3.1.3.4 3.6.1.27] D SpyM50872 putative cardiolipin synthetase K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism D SpyM50551 glycosyl hydrolase family 2 protein K01190 lacZ; beta-galactosidase [EC:3.2.1.23] C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:spf00230] D SpyM51502 putative ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D SpyM51112 deoB; phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7] D SpyM50618 putative phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D SpyM50860 pgmA; putative phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D SpyM50016 prsA1; ribose-phosphate pyrophosphokinase 1 K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D SpyM50943 prsA2; putative ribose-phosphate pyrophosphokinase 2 K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D SpyM50023 purF; putative amidophosphoribosyltransferase precursor K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D SpyM50029 purD; phosphoribosylamine-glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D SpyM50025 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D SpyM50022 putative phosphoribosylformylglycinamidine synthase protein K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] D SpyM50024 purM; phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D SpyM50031 purK; putative phosphoribosylaminoimidazole carboxylase ATPase subunit K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] D SpyM50030 purE; putative phosphoribosylaminoimidazole carboxylase catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D SpyM50033 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D SpyM51079 apt; adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D SpyM51130 putative surface-anchored 5'-nucleotidase K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5] D SpyM51110 punA; putative purine nucleoside phosphorylase K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1] D SpyM51109 deoD; putative purine nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] D SpyM50012 hpt; hypoxanthine-guanine phosphoribosyltransferase K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] D SpyM51830 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D SpyM51554 HAM1 protein homolog K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D SpyM50932 xpt; putative xanthine phosphoribosyltransferase K03816 xpt; xanthine phosphoribosyltransferase [EC:2.4.2.22] D SpyM50879 guaA; GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D SpyM50933 GMP reductase K00364 guaC; GMP reductase [EC:1.7.1.7] D SpyM50450 gmk; guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8] D SpyM50737 putative ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D SpyM51512 nrdE; ribonucleoside-diphosphate reductase alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D SpyM51514 nrdF; ribonucleoside-diphosphate reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D SpyM50735 putative ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D SpyM51752 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D SpyM51658 relA; GTP pyrophosphokinase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D SpyM50941 conserved hypothetical protein K07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5] D SpyM51129 conserved hypothetical protein K07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5] D SpyM50131 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D SpyM50065 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D SpyM50582 arcC; carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] C 00240 Pyrimidine metabolism [PATH:spf00240] D SpyM51164 carB; carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D SpyM51165 carA; carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D SpyM51166 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D SpyM51099 pyrC; putative dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3] D SpyM50695 pyrD; putative dihydroorotate dehydrogenase K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1] D SpyM51104 pyrE; orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D SpyM51105 pyrF; orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D SpyM51489 pyrH; uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D SpyM50244 pyrG; putative CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2] D SpyM51189 cmk; cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D SpyM50744 udk; uridine kinase K00876 udk; uridine kinase [EC:2.7.1.48] D SpyM51130 putative surface-anchored 5'-nucleotidase K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5] D SpyM50263 udp; putative uridine phosphorylase K00757 udp; uridine phosphorylase [EC:2.4.2.3] D SpyM51531 upp; uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9] D SpyM51168 pyrR; PyrR bifunctional protein [includes: pyrimidine operon regulatory protein; uracil phosphoribosyltransferase] K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9] D SpyM50855 cdd; cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5] D SpyM51752 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D SpyM50737 putative ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D SpyM51512 nrdE; ribonucleoside-diphosphate reductase alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D SpyM51514 nrdF; ribonucleoside-diphosphate reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D SpyM50735 putative ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D SpyM50302 putative cytidine and deoxycytidylate deaminase K01493 comEB; dCMP deaminase [EC:3.5.4.12] D SpyM51528 tmk; thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D SpyM50178 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D SpyM50928 tdk; putative thymidine kinase K00857 tdk; thymidine kinase [EC:2.7.1.21] D SpyM51120 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] D SpyM50937 putative NADP-dependent L-serine/L-allo-threonine dehydrogenase K16066 ydfG; 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:spf00250] D SpyM50329 asnB; putative L-asparaginase K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D SpyM50584 asnA; aspartate--ammonia ligase K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1] D SpyM51327 aspC; aspartate aminotransferase K22457 E2.6.1.14; asparagine---oxo-acid transaminase [EC:2.6.1.14] D SpyM50332 putative aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D SpyM50131 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D SpyM50033 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D SpyM51166 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D SpyM50979 putative succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D SpyM50255 glnA; putative glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D SpyM51164 carB; carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D SpyM51165 carA; carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D SpyM50815 glmS; glucosamine--fructose-6-phosphate aminotransferase [isomerizing] K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D SpyM50023 purF; putative amidophosphoribosyltransferase precursor K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:spf00260] D SpyM50923 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D SpyM51596 putative glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D SpyM50696 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D SpyM50937 putative NADP-dependent L-serine/L-allo-threonine dehydrogenase K16066 ydfG; 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-] D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SpyM51814 sdhA; putative L-serine dehydratase, alpha chain K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] D SpyM51813 sdhB; putative L-serine dehydratase, beta chain K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] C 00270 Cysteine and methionine metabolism [PATH:spf00270] D SpyM51631 cysE; serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D SpyM50462 cysM; putative cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47] D SpyM50140 putative cystathionine beta-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D SpyM51419 putative S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D SpyM50751 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D SpyM51500 mtnN; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9] D SpyM50747 conserved hypothetical protein K08968 msrC; L-methionine (R)-S-oxide reductase [EC:1.8.4.14] D SpyM50442 luxS; S-ribosylhomocysteinase K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21] D SpyM51094 putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D SpyM50917 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D SpyM51814 sdhA; putative L-serine dehydratase, alpha chain K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] D SpyM51813 sdhB; putative L-serine dehydratase, beta chain K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] C 00280 Valine, leucine and isoleucine degradation [PATH:spf00280] D SpyM51094 putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM51121 mvaS; 3-hydroxy-3-methylglutaryl coenzyme A synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:spf00290] D SpyM51094 putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D SpyM50332 putative aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] C 00300 Lysine biosynthesis D SpyM50703 murF; putative UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] C 00310 Lysine degradation [PATH:spf00310] D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM50979 putative succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D SpyM50115 atoD1; acetate CoA-transferase alpha subunit 1 K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D SpyM50446 atoD2; acetate CoA-transferase alpha subunit 2 K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D SpyM50116 atoA1; acetate CoA-transferase beta subunit 1 K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] C 00220 Arginine biosynthesis [PATH:spf00220] D SpyM50579 arcB; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D SpyM50577 arcA; arginine deiminase K01478 arcA; arginine deiminase [EC:3.5.3.6] D SpyM50255 glnA; putative glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D SpyM50582 arcC; carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] D SpyM50332 putative aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] C 00330 Arginine and proline metabolism [PATH:spf00330] D SpyM51103 putative amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D SpyM51666 putative surface-anchored amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D SpyM50094 proC; putative pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2] D SpyM50421 proA; gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] C 00340 Histidine metabolism [PATH:spf00340] D SpyM51735 hutH; histidine ammonia-lyase K01745 hutH; histidine ammonia-lyase [EC:4.3.1.3] D SpyM51729 hutU; urocanate hydratase K01712 hutU; urocanate hydratase [EC:4.2.1.49] D SpyM51728 hutI; imidazolonepropionase K01468 hutI; imidazolonepropionase [EC:3.5.2.7] D SpyM51736 hutG; formiminoglutamase K01479 hutG; formiminoglutamase [EC:3.5.3.8] D SpyM51730 putative glutamate formiminotransferase K00603 fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2] C 00350 Tyrosine metabolism [PATH:spf00350] D SpyM50039 adhE; aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase] K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D SpyM50040 adhP; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D SpyM50979 putative succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] C 00360 Phenylalanine metabolism D SpyM51103 putative amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D SpyM51666 putative surface-anchored amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] C 00380 Tryptophan metabolism [PATH:spf00380] D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM51103 putative amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D SpyM51666 putative surface-anchored amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:spf00400] D SpyM50558 DAHP synthetase I family protein K03856 AROA2; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D SpyM50557 aroB; 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4] D SpyM51183 aroD; 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10] D SpyM51423 aroE.2; putative shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] D SpyM50759 aroK; putative shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71] D SpyM50758 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D SpyM51182 aroF; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D SpyM51668 trpG; anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D SpyM51255 chorismate mutase type II protein K04516 AROA1; chorismate mutase [EC:5.4.99.5] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism C 00430 Taurine and hypotaurine metabolism [PATH:spf00430] D SpyM50938 pta; putative phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D SpyM50092 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:spf00450] D SpyM50140 putative cystathionine beta-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D SpyM50222 csdB; putative cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D SpyM50431 putative thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D SpyM51515 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism [PATH:spf00460] D SpyM50329 asnB; putative L-asparaginase K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D SpyM50584 asnA; aspartate--ammonia ligase K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1] D SpyM50923 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism [PATH:spf00470] D SpyM50314 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D SpyM50702 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D SpyM50792 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D SpyM50794 dltC; D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D SpyM51555 glr; glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D SpyM50599 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] C 00480 Glutathione metabolism [PATH:spf00480] D SpyM50849 pepN; putative lysyl-aminopeptidase K01256 pepN; aminopeptidase N [EC:3.4.11.2] D SpyM51088 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D SpyM51180 gor; glutathione reductase K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7] D SpyM51360 putative glutathione peroxidase K00432 gpx; glutathione peroxidase [EC:1.11.1.9] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation [PATH:spf00511] D SpyM50551 glycosyl hydrolase family 2 protein K01190 lacZ; beta-galactosidase [EC:3.2.1.23] D SpyM50538 glycosyl hydrolases family protein K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24] C 00540 Lipopolysaccharide biosynthesis C 00542 O-Antigen repeat unit biosynthesis [PATH:spf00542] D SpyM50219 rgpG; putative glycosyl transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:spf00541] D SpyM51826 hasC1; UTP--glucose-1-phosphate uridylyltransferase 1 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D SpyM50172 hasC2; UTP--glucose-1-phosphate uridylyltransferase 2 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D SpyM51825 hasB; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D SpyM51415 putative UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D SpyM51073 rmlA; glucose-1-phosphate thymidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D SpyM51071 rmlB; putative dTDP-glucose-4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D SpyM51072 rmlC; putative dTDP-4-keto-6-deoxyglucose-3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D SpyM50311 pmi; mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D SpyM51503 gcaD; bifunctional GlmU protein [includes: UDP-N-acetylglucosamine pyrophosphorylase; glucosamine-1-phosphate N-acetyltransferase] K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] C 00550 Peptidoglycan biosynthesis [PATH:spf00550] D SpyM51224 murA1; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D SpyM50752 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D SpyM50963 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D SpyM51565 murC; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D SpyM50599 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D SpyM50702 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D SpyM50703 murF; putative UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D SpyM51479 dgk; diacylglycerol kinase K00887 dgkA; undecaprenol kinase [EC:2.7.1.66] D SpyM51648 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D SpyM50217 bacA; undecaprenol kinase (bacitracin resistance protein) K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D SpyM51544 PAP2 superfamily protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D SpyM50426 mraY; phospho-N-acetylmuramoyl-pentapeptide-transfera se K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D SpyM50600 murG; putative UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyr ophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D SpyM50436 pbp1A; putative penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D SpyM51715 pbp2A; penicillin-binding protein 2a K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] D SpyM50971 putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D SpyM50226 putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D SpyM50343 putative D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D SpyM51533 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-dia minopimelate ligase K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7] D SpyM50999 Mur ligase family protein K23393 murT; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13] D SpyM51000 conserved hypothetical protein K07009 gatD; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13] D SpyM50878 murM; putative peptidoglycan branched peptide synthesis protein MurM K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10] D SpyM51352 murM; putative peptidoglycan pentaglycine interpeptide biosynthesis protein K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10] D SpyM51353 murN; putative peptidoglycan branched peptide synthesis protein K12554 murN; alanine adding enzyme [EC:2.3.2.-] D SpyM50080 pbp1B; putative penicillin-binding protein 1B K03693 pbp1b; penicillin-binding protein 1B D SpyM50425 pbpX; putative penicillin binding protein 2x K12556 pbp2X; penicillin-binding protein 2X C 00552 Teichoic acid biosynthesis [PATH:spf00552] D SpyM50217 bacA; undecaprenol kinase (bacitracin resistance protein) K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D SpyM51544 PAP2 superfamily protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D SpyM50219 rgpG; putative glycosyl transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D SpyM50792 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D SpyM50794 dltC; D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D SpyM50793 dltB; putative activated D-alanine transport protein K03739 dltB; membrane protein involved in D-alanine export D SpyM50795 dltD; putative D-alanyl-lipoteichoic acid biosynthesis protein K03740 dltD; D-alanine transfer protein D SpyM50371 LytR family regulatory protein K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-] D SpyM50760 cell envelope-related transcriptional attenuator domain protein K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-] D SpyM51185 putative sulfatase K19005 ltaS; lipoteichoic acid synthase [EC:2.7.8.20] D SpyM51444 putative glycosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis [PATH:spf00543] D SpyM50219 rgpG; putative glycosyl transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D SpyM51631 cysE; serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:spf00730] D SpyM51177 putative cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D SpyM50944 putative cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D SpyM51176 thiI; putative thiamine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D SpyM50202 engC; probable GTPase EngC K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D SpyM50204 thiN; putative thiamin pyrophosphokinase K00949 thiN; thiamine pyrophosphokinase [EC:2.7.6.2] D SpyM50065 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] C 00740 Riboflavin metabolism [PATH:spf00740] D SpyM50367 putative haloacid dehalogenase-like hydrolase K21064 ycsE; 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.104] D SpyM50838 ribC; putative riboflavin biosynthesis protein K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] D SpyM50953 putative class B acid phosphatase K03788 aphA; acid phosphatase (class B) [EC:3.1.3.2] D SpyM51502 putative ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] C 00750 Vitamin B6 metabolism [PATH:spf00750] D SpyM50875 conserved hypothetical protein K00868 pdxK; pyridoxine kinase [EC:2.7.1.35] D SpyM50238 thiD; putative phosphomethylpyrimidine kinase K00868 pdxK; pyridoxine kinase [EC:2.7.1.35] C 00760 Nicotinate and nicotinamide metabolism [PATH:spf00760] D SpyM50773 nadC; putative nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D SpyM50433 nicotinate phosphoribosyltransferase (NAPRTase) family protein K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21] D SpyM51110 punA; putative purine nucleoside phosphorylase K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1] D SpyM51109 deoD; putative purine nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] D SpyM51130 putative surface-anchored 5'-nucleotidase K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5] D SpyM51591 putative nicotinate-nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18] D SpyM50434 nadE; NH(3)-dependent NAD(+) synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5] D SpyM50134 nga; nicotine adenine dinucleotide glycohydrolase precursor K18153 nga; NAD+ glycohydrolase [EC:3.2.2.5] D SpyM50940 ppnK; putative inorganic polyphosphate/ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] D SpyM50979 putative succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] C 00770 Pantothenate and CoA biosynthesis [PATH:spf00770] D SpyM51149 putative ketopantoate reductase K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169] D SpyM50853 coaA; pantothenate kinase K00867 coaA; type I pantothenate kinase [EC:2.7.1.33] D SpyM50863 dpfB; putative pantothenate metabolism flavoprotein K21977 coaB; phosphopantothenate---cysteine ligase (CTP) [EC:6.3.2.5] D SpyM50862 coaC; putative phosphopantothenoylcysteine decarboxylase K01598 PPCDC; phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36] D SpyM50586 coaD; phosphopantetheine adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D SpyM51460 coaE; dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24] D SpyM50313 acpS; holo-[acyl-carrier protein] synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7] D SpyM51094 putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] C 00780 Biotin metabolism [PATH:spf00780] D SpyM50356 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D SpyM51506 putative short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SpyM50355 fabG; 3-oxoacyl-[acyl-carrier protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SpyM50358 fabZ; (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D SpyM50749 birA; BirA bifunctional protein [includes: biotin operon repressor; biotin--[acetyl-CoA-carboxylase] synthetase] K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism [PATH:spf00785] D SpyM50864 conserved hypothetical protein K16869 lipL; octanoyl-[GcvH]:protein N-octanoyltransferase [EC:2.3.1.204] D SpyM50870 lplA; putative lipoate-protein ligase A K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D SpyM51001 putative lipoate-protein ligase A K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SpyM51008 pdhA; putative pyruvate dehydrogenase E1 component,alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D SpyM51007 pdhB; putative pyruvate dehydrogenase E1 component,beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D SpyM51006 pdhC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] C 00790 Folate biosynthesis [PATH:spf00790] D SpyM50967 folE; GTP cyclohydrolase I K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16] D SpyM50965 folQ; dihydroneopterin aldolase K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81] D SpyM50964 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridi ne pyrophosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D SpyM50966 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15] D SpyM51119 dyr; dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D SpyM50968 folC1; putative folypolyglutamate synthase 1 K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D SpyM51179 folC2; putative folypolyglutamate synthase 2 K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D SpyM51667 putative chorismate binding enzyme K03342 pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38] C 00670 One carbon pool by folate [PATH:spf00670] D SpyM51119 dyr; dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D SpyM51732 fhs2; putative formate--tetrahydrofolate ligase 2 K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] D SpyM50871 fhs1; formate--tetrahydrofolate ligase 1 K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] D SpyM50619 folD; FolD bifunctional protein [includes: methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase] K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D SpyM51731 putative formiminotetrahydrofolate cyclodeaminase K01500 fchA; methenyltetrahydrofolate cyclohydrolase [EC:3.5.4.9] D SpyM50923 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D SpyM50025 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D SpyM51730 putative glutamate formiminotransferase K00603 fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2] D SpyM50453 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D SpyM51120 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] C 00830 Retinol metabolism C 00860 Porphyrin metabolism C 00130 Ubiquinone and other terpenoid-quinone biosynthesis B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:spf00900] D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM51121 mvaS; 3-hydroxy-3-methylglutaryl coenzyme A synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D SpyM51122 mvaA; 3-hydroxy-3-methylglutaryl-coenzyme A reductase K00054 mvaA; hydroxymethylglutaryl-CoA reductase [EC:1.1.1.88] D SpyM51126 mvaK1; mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36] D SpyM51124 mvaK2; phosphomevalonate kinase K00938 E2.7.4.2; phosphomevalonate kinase [EC:2.7.4.2] D SpyM51125 mvaD; mevalonate diphosphate decarboxylase K01597 MVD; diphosphomevalonate decarboxylase [EC:4.1.1.33] D SpyM51123 fni; isopentenyl-diphosphate delta-isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2] D SpyM50622 fps; putative geranyltranstransferase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29] D SpyM51648 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation [PATH:spf00903] D SpyM50796 putative membrane protein K14731 mlhB; epsilon-lactone hydrolase [EC:3.1.1.83] C 00907 Pinene, camphor and geraniol degradation C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D SpyM50415 tkt; putative transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis [PATH:spf00523] D SpyM51073 rmlA; glucose-1-phosphate thymidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D SpyM51071 rmlB; putative dTDP-glucose-4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D SpyM51072 rmlC; putative dTDP-4-keto-6-deoxyglucose-3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics D SpyM51071 rmlB; putative dTDP-glucose-4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis C 00332 Carbapenem biosynthesis D SpyM50421 proA; gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] C 00261 Monobactam biosynthesis C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:spf00521] D SpyM50595 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] D SpyM50618 putative phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D SpyM50860 pgmA; putative phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D SpyM50841 putative myo-inositol-1(or 4)-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D SpyM51073 rmlA; glucose-1-phosphate thymidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D SpyM51071 rmlB; putative dTDP-glucose-4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D SpyM51072 rmlC; putative dTDP-4-keto-6-deoxyglucose-3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] C 00524 Neomycin, kanamycin and gentamicin biosynthesis D SpyM50595 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] C 00525 Acarbose and validamycin biosynthesis [PATH:spf00525] D SpyM51073 rmlA; glucose-1-phosphate thymidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D SpyM51071 rmlB; putative dTDP-glucose-4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] C 00401 Novobiocin biosynthesis C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis D SpyM51668 trpG; anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] C 00333 Prodigiosin biosynthesis D SpyM50354 fabD; putative malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D SpyM51506 putative short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SpyM50355 fabG; 3-oxoacyl-[acyl-carrier protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics D SpyM50019 putative acyl carrier protein K02078 acpP; acyl carrier protein D SpyM50352 acpP; acyl carrier protein (ACP) K02078 acpP; acyl carrier protein C 00999 Biosynthesis of various plant secondary metabolites [PATH:spf00999] D SpyM51419 putative S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D SpyM50751 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D SpyM51423 aroE.2; putative shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation [PATH:spf00362] D SpyM50929 putative 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D SpyM50900 putative glutaconyl-CoA decarboxylase beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D SpyM50894 putative Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D SpyM50901 putative glutaconyl-CoA decarboxylase gamma subunit K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma D SpyM50895 putative decarboxylase gamma chain K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00627 Aminobenzoate degradation [PATH:spf00627] D SpyM51103 putative amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D SpyM51666 putative surface-anchored amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D SpyM51560 putative acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D SpyM50115 atoD1; acetate CoA-transferase alpha subunit 1 K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D SpyM50446 atoD2; acetate CoA-transferase alpha subunit 2 K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D SpyM50116 atoA1; acetate CoA-transferase beta subunit 1 K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation [PATH:spf00625] D SpyM50040 adhP; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D SpyM50039 adhE; aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase] K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] C 00361 Chlorocyclohexane and chlorobenzene degradation C 00623 Toluene degradation C 00622 Xylene degradation D SpyM50929 putative 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00633 Nitrotoluene degradation C 00642 Ethylbenzene degradation C 00643 Styrene degradation [PATH:spf00643] D SpyM51103 putative amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D SpyM51666 putative surface-anchored amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] C 00791 Atrazine degradation C 00930 Caprolactam degradation D SpyM50796 putative membrane protein K14731 mlhB; epsilon-lactone hydrolase [EC:3.1.1.83] C 00363 Bisphenol degradation C 00621 Dioxin degradation D SpyM50929 putative 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00626 Naphthalene degradation [PATH:spf00626] D SpyM50040 adhP; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D SpyM50039 adhE; aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase] K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:spf03020] D SpyM50081 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D SpyM50082 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D SpyM50069 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D SpyM50451 rpoZ; DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D SpyM50243 rpoE; putative DNA-directed RNA polymerase, delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta C 03022 Basal transcription factors C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:spf03010] D SpyM51092 putative 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1 D SpyM51739 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D SpyM50050 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D SpyM51805 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D SpyM50061 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D SpyM50295 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6 D SpyM50210 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D SpyM50058 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D SpyM51619 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D SpyM50043 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D SpyM50068 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D SpyM50209 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D SpyM50067 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D SpyM50057 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D SpyM50261 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D SpyM51638 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D SpyM51159 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D SpyM50053 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D SpyM50297 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D SpyM50048 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D SpyM50852 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20 D SpyM51210 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D SpyM51490 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D SpyM50047 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D SpyM50044 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D SpyM50045 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4 D SpyM50056 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D SpyM50059 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D SpyM50972 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D SpyM51808 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9 D SpyM50973 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D SpyM51491 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D SpyM51620 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D SpyM50054 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D SpyM50063 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D SpyM50051 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D SpyM50070 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D SpyM50060 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D SpyM51253 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D SpyM51186 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D SpyM51174 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D SpyM50049 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D SpyM50046 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D SpyM50055 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D SpyM51172 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D SpyM50247 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D SpyM50052 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D SpyM50062 rpmD; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D SpyM51258 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D SpyM51790 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D SpyM51714 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D SpyM51791 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D SpyM51458A rpmGB; 50S ribosomal protein L33 2 K02913 RP-L33; large subunit ribosomal protein L33 D SpyM50190 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34 D SpyM51187 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35 D SpyM50066A rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36 D 16S_rRNA-1 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 16S_rRNA-3 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 16S_rRNA-6 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 16S_rRNA-2 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 16S_rRNA-4 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 16S_rRNA-5 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 23S_rRNA-2 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 23S_rRNA-1 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 23S_rRNA-3 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 23S_rRNA-4 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 23S_rRNA-5 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 23S_rRNA-6 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 5S_rRNA-1 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D 5S_rRNA-3 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D 5S_rRNA-2 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D 5S_rRNA-4 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D 5S_rRNA-5 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D 5S_rRNA-6 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA C 00970 Aminoacyl-tRNA biosynthesis [PATH:spf00970] D tRNA-Ala-1 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala D tRNA-Ala-2 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala D tRNA-Ala-4 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala D tRNA-Ala-3 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala D tRNA-Ala-5 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala D tRNA-Ala-6 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala D tRNA-Arg-7 tRNA-Arg_(TCT); tRNA-Arg K14219 tRNA-Arg; tRNA Arg D tRNA-Arg-1 tRNA-Arg_(ACG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg D tRNA-Arg-3 tRNA-Arg_(ACG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg D tRNA-Arg-4 tRNA-Arg_(CCG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg D tRNA-Arg-5 tRNA-Arg_(CCT); tRNA-Arg K14219 tRNA-Arg; tRNA Arg D tRNA-Arg-6 tRNA-Arg_(ACG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg D tRNA-Arg-2 tRNA-Arg_(ACG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg D tRNA-Asn-1 tRNA-Asn_(GTT); tRNA-Asn K14220 tRNA-Asn; tRNA Asn D tRNA-Asn-2 tRNA-Asn_(GTT); tRNA-Asn K14220 tRNA-Asn; tRNA Asn D tRNA-Asn-3 tRNA-Asn_(GTT); tRNA-Asn K14220 tRNA-Asn; tRNA Asn D tRNA-Asp-2 tRNA-Asp_(GTC); tRNA-Asp K14221 tRNA-Asp; tRNA Asp D tRNA-Asp-3 tRNA-Asp_(GTC); tRNA-Asp K14221 tRNA-Asp; tRNA Asp D tRNA-Asp-1 tRNA-Asp_(GTC); tRNA-Asp K14221 tRNA-Asp; tRNA Asp D tRNA-Cys tRNA-Cys_(GCA); tRNA-Cys K14222 tRNA-Cys; tRNA Cys D tRNA-Gln-2 tRNA-Gln_(TTG); tRNA-Gln K14223 tRNA-Gln; tRNA Gln D tRNA-Gln-1 tRNA-Gln_(TTG); tRNA-Gln K14223 tRNA-Gln; tRNA Gln D tRNA-Glu-1 tRNA-Glu_(TTC); tRNA-Glu K14224 tRNA-Glu; tRNA Glu D tRNA-Glu-3 tRNA-Glu_(TTC); tRNA-Glu K14224 tRNA-Glu; tRNA Glu D tRNA-Glu-2 tRNA-Glu_(TTC); tRNA-Glu K14224 tRNA-Glu; tRNA Glu D tRNA-Gly-1 tRNA-Gly_(GCC); tRNA-Gly K14225 tRNA-Gly; tRNA Gly D tRNA-Gly-2 tRNA-Gly_(GCC); tRNA-Gly K14225 tRNA-Gly; tRNA Gly D tRNA-Gly-3 tRNA-Gly_(TCC); tRNA-Gly K14225 tRNA-Gly; tRNA Gly D tRNA-Gly-4 tRNA-Gly_(TCC); tRNA-Gly K14225 tRNA-Gly; tRNA Gly D tRNA-His tRNA-His_(GTG); tRNA-His K14226 tRNA-His; tRNA His D tRNA-Ile-2 tRNA-Ile_(GAT); tRNA-Ile K14227 tRNA-Ile; tRNA Ile D tRNA-Ile-3 tRNA-Ile_(GAT); tRNA-Ile K14227 tRNA-Ile; tRNA Ile D tRNA-Ile-1 tRNA-Ile_(GAT); tRNA-Ile K14227 tRNA-Ile; tRNA Ile D tRNA-Leu-1 tRNA-Leu_(TAG); tRNA-Leu K14228 tRNA-Leu; tRNA Leu D tRNA-Leu-5 tRNA-Leu_(CAA); tRNA-Leu K14228 tRNA-Leu; tRNA Leu D tRNA-Leu-2 tRNA-Leu_(TAA); tRNA-Leu K14228 tRNA-Leu; tRNA Leu D tRNA-Leu-3 tRNA-Leu_(TAG); tRNA-Leu K14228 tRNA-Leu; tRNA Leu D tRNA-Leu-7 tRNA-Leu_(TAG); tRNA-Leu K14228 tRNA-Leu; tRNA Leu D tRNA-Leu-4 tRNA-Leu_(TAA); tRNA-Leu K14228 tRNA-Leu; tRNA Leu D tRNA-Leu-6 tRNA-Leu_(AAG); tRNA-Leu K14228 tRNA-Leu; tRNA Leu D tRNA-Lys-1 tRNA-Lys_(TTT); tRNA-Lys K14229 tRNA-Lys; tRNA Lys D tRNA-Lys-2 tRNA-Lys_(TTT); tRNA-Lys K14229 tRNA-Lys; tRNA Lys D tRNA-Lys-3 tRNA-Lys_(TTT); tRNA-Lys K14229 tRNA-Lys; tRNA Lys D tRNA-Lys-4 tRNA-Lys_(CTT); tRNA-Lys K14229 tRNA-Lys; tRNA Lys D tRNA-Met-1 tRNA-Met_(CAT); tRNA-Met K14230 tRNA-Met; tRNA Met D tRNA-Met-2 tRNA-Met_(CAT); tRNA-Met K14230 tRNA-Met; tRNA Met D tRNA-Met-3 tRNA-Met_(CAT); tRNA-Met K14230 tRNA-Met; tRNA Met D tRNA-Phe-1 tRNA-Phe_(GAA); tRNA-Phe K14231 tRNA-Phe; tRNA Phe D tRNA-Phe-2 tRNA-Phe_(GAA); tRNA-Phe K14231 tRNA-Phe; tRNA Phe D tRNA-Pro-1 tRNA-Pro_(TGG); tRNA-Pro K14232 tRNA-Pro; tRNA Pro D tRNA-Pro-2 tRNA-Pro_(TGG); tRNA-Pro K14232 tRNA-Pro; tRNA Pro D tRNA-Ser-4 tRNA-Ser_(GGA); tRNA-Ser K14233 tRNA-Ser; tRNA Ser D tRNA-Ser-1 tRNA-Ser_(TGA); tRNA-Ser K14233 tRNA-Ser; tRNA Ser D tRNA-Ser-2 tRNA-Ser_(GCT); tRNA-Ser K14233 tRNA-Ser; tRNA Ser D tRNA-Ser-3 tRNA-Ser_(TGA); tRNA-Ser K14233 tRNA-Ser; tRNA Ser D tRNA-Thr-1 tRNA-Thr_(TGT); tRNA-Thr K14234 tRNA-Thr; tRNA Thr D tRNA-Thr-3 tRNA-Thr_(TGT); tRNA-Thr K14234 tRNA-Thr; tRNA Thr D tRNA-Thr-4 tRNA-Thr_(GGT); tRNA-Thr K14234 tRNA-Thr; tRNA Thr D tRNA-Thr-2 tRNA-Thr_(TGT); tRNA-Thr K14234 tRNA-Thr; tRNA Thr D tRNA-Trp tRNA-Trp_(CCA); tRNA-Trp K14235 tRNA-Trp; tRNA Trp D tRNA-Tyr-2 tRNA-Tyr_(GTA); tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D tRNA-Tyr-1 tRNA-Tyr_(GTA); tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D tRNA-Val-1 tRNA-Val_(TAC); tRNA-Val K14237 tRNA-Val; tRNA Val D tRNA-Val-3 tRNA-Val_(TAC); tRNA-Val K14237 tRNA-Val; tRNA Val D tRNA-Val-2 tRNA-Val_(TAC); tRNA-Val K14237 tRNA-Val; tRNA Val D tRNA-Val-4 tRNA-Val_(TAC); tRNA-Val K14237 tRNA-Val; tRNA Val D SpyM50182 gltX; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D SpyM50338 gatA; glutamyl-tRNA amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D SpyM50339 gatB; glutamyl-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D SpyM50337 gatC; glutamyl-tRNA amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D SpyM50726 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D SpyM51788 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D SpyM51326 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D SpyM50405 glyQ; glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D SpyM50406 glyS; glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D SpyM51443 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D SpyM50362 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D SpyM51628 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D SpyM51515 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D SpyM50453 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D SpyM50564 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D SpyM50141 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D SpyM50609 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D SpyM51368 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D SpyM51783 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D SpyM51645 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D SpyM51789 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D SpyM51220 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D SpyM51219 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D SpyM50079 tyrS; putative tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D SpyM51831 trsA; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:spf03060] D SpyM50064 secY; preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY D SpyM51713 putative preprotein translocase SecE subunit K03073 secE; preprotein translocase subunit SecE D SpyM51457 secG; putative protein-export membrane protein K03075 secG; preprotein translocase subunit SecG D SpyM51649 putative preprotein translocase subunit K03210 yajC; preprotein translocase subunit YajC D SpyM51561 membrane protein OxaA 2 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase D SpyM50188 membrane protein OxaA 1 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase D SpyM50312 secA; putative preprotein SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D SpyM50883 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D SpyM51388 ftsY; putative cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor D SpyM50285 spi; putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D SpyM50814 sipC; putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D SpyM50105 putative signal peptidase K03100 lepB; signal peptidase I [EC:3.4.21.89] D SpyM51170 lspA; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:spf04122] D SpyM51177 putative cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D SpyM50944 putative cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D SpyM51812 putative tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D SpyM51176 thiI; putative thiamine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] C 03050 Proteasome C 03018 RNA degradation [PATH:spf03018] D SpyM51248 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D SpyM51633 pnpA; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D SpyM51456 rnr; putative exoribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1] D SpyM50706 DEAD box helicase family protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D SpyM50449 putative phosphohydrolase K18682 rny; ribonucrease Y [EC:3.1.-.-] D SpyM50256 metallo-beta-lactamase superfamily protein K12574 rnj; ribonuclease J [EC:3.1.-.-] D SpyM51012 metallo-beta-lactamase superfamily protein K12574 rnj; ribonuclease J [EC:3.1.-.-] D SpyM50812 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D SpyM50347 dnaK; chaperone protein DnaK (heat shock protein 70) K04043 dnaK; molecular chaperone DnaK D SpyM51721 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] B B 09124 Replication and repair C 03030 DNA replication [PATH:spf03030] D SpyM50268 putative exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SpyM50811 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D SpyM51644 polC; DNA polymerase III PolC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D SpyM50748 dnaH; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D SpyM51527 holB; putative DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D SpyM50713 putative DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D SpyM50002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D SpyM51807 dnaC; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D SpyM51208 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D SpyM50296 ssb; single strand binding protein (SSB) K03111 ssb; single-strand DNA-binding protein D SpyM50099 putative single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D SpyM50907 rnh; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D SpyM50286 ribonuclease HIII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4] D SpyM50152 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D SpyM51235 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03410 Base excision repair [PATH:spf03410] D SpyM51077 nth; putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D SpyM51100 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D SpyM50293 putative A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D SpyM51461 fpg; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D SpyM51760 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D SpyM51520 exoA; exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D SpyM50152 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D SpyM51080 putative single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D SpyM51235 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03420 Nucleotide excision repair [PATH:spf03420] D SpyM50006 trcF; putative transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D SpyM50300 uvrA; UvrABC system protein A (UvrA protein) K03701 uvrA; excinuclease ABC subunit A D SpyM50790 uvrB; UvrABC system protein B (UvrB protein) K03702 uvrB; excinuclease ABC subunit B D SpyM50978 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C D SpyM50823 pcrA; putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D SpyM50152 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D SpyM51235 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03430 Mismatch repair [PATH:spf03430] D SpyM51780 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS D SpyM50289 mutS2; putative DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2 D SpyM51763 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL D SpyM50823 pcrA; putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D SpyM50620 xseA; putative exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D SpyM50621 xseB; putative exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D SpyM51080 putative single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D SpyM50296 ssb; single strand binding protein (SSB) K03111 ssb; single-strand DNA-binding protein D SpyM50099 putative single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D SpyM50811 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D SpyM51644 polC; DNA polymerase III PolC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D SpyM50002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D SpyM50748 dnaH; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D SpyM50713 putative DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D SpyM51527 holB; putative DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D SpyM50268 putative exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SpyM51235 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03440 Homologous recombination [PATH:spf03440] D SpyM51080 putative single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D SpyM50296 ssb; single strand binding protein (SSB) K03111 ssb; single-strand DNA-binding protein D SpyM50099 putative single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D SpyM51828 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF D SpyM50017 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) D SpyM50701 recR; recombination protein RecR K06187 recR; recombination protein RecR D SpyM51758 recA; RecA recombinase (recombinase A) K03553 recA; recombination protein RecA D SpyM50152 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D SpyM51761 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA D SpyM50035 ruvB; Holliday junction DNA helicase, subunit B K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D SpyM50326 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D SpyM50284 hypothetical protein K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D SpyM50811 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D SpyM51644 polC; DNA polymerase III PolC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D SpyM50002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D SpyM50748 dnaH; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D SpyM50713 putative DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D SpyM51527 holB; putative DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D SpyM50268 putative exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SpyM50452 priA; putative primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] C 03450 Non-homologous end-joining C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 [PATH:spf03250] D SpyM51494 putative cyclophilin type peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus and Lyssavirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:spf02010] D SpyM50980 extracellular solute-binding protein K02012 afuA; iron(III) transport system substrate-binding protein D SpyM50959 potD; spermidine/putrescine extracellular binding protein K11069 potD; spermidine/putrescine transport system substrate-binding protein D SpyM50960 potC; spermidine/putrescine ABC transporter permease protein K11070 potC; spermidine/putrescine transport system permease protein D SpyM50961 potB; putative spermidine/putrescine ABC transporter permease protein K11071 potB; spermidine/putrescine transport system permease protein D SpyM50962 potA; putative spermidine/putrescine ABC transporter ATP-binding protein K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11] D SpyM50151 putative glycine-betaine binding permease protein K02001 proW; glycine betaine/proline transport system permease protein D SpyM50150 putative glycine betaine transport ATP-binding protein K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9] D SpyM50934 ABC-type glycine betaine transport system protein K05845 opuC; osmoprotectant transport system substrate-binding protein D SpyM50935 ABC-type glycine betaine transport system ATP-binding protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9] D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D SpyM50802 malX; putative maltose/maltodextrin-binding protein precursor K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein D SpyM50801 malC; putative maltose/maltodextrin ABC transport system permease protein K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D SpyM50800 malD; putative maltose/maltodextrin ABC transport system permease protein K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D SpyM50547 extracellular solute-binding protein K17318 lplA; putative aldouronate transport system substrate-binding protein D SpyM50545 binding-protein-dependent transport system membrane protein K17319 lplB; putative aldouronate transport system permease protein D SpyM50546 binding-protein-dependent transport system membrane protein K17320 lplC; putative aldouronate transport system permease protein D SpyM50132 basic lipoprotein K07335 bmpA; basic membrane protein A and related proteins D SpyM50856 putative lipoprotein K07335 bmpA; basic membrane protein A and related proteins D SpyM50858 ABC transporter permease protein K23535 nupB; general nucleoside transport system permease protein D SpyM50859 ABC transporter permease protein K23536 nupC; general nucleoside transport system permease protein D SpyM50857 ABC transporter ATP-binding protein K23537 nupA; general nucleoside transport system ATP-binding protein D SpyM50843 pstS; putative phosphate ABC transporter,extracellular phosphate-binding lipoprotein K02040 pstS; phosphate transport system substrate-binding protein D SpyM50844 pstC; putative phosphate ABC transporter permease protein K02037 pstC; phosphate transport system permease protein D SpyM50845 putative phosphate ABC transporter permease protein K02038 pstA; phosphate transport system permease protein D SpyM50847 pstB1; phosphate import ATP-binding protein 1 K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D SpyM50846 pstB2; phosphate import ATP-binding protein 2 K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D SpyM50789 putative glutamine ABC transporter,glutamine-binding protein/permease protein K10036 glnH; glutamine transport system substrate-binding protein D SpyM50788 glnQ1; putative glutamine ABC transporter, ATP-binding protein 1 K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1] D SpyM51102 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D SpyM51585 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D SpyM51101 transport system membrane protein K10009 tcyB; L-cystine transport system permease protein D SpyM50428 ABC transporter permease protein K10009 tcyB; L-cystine transport system permease protein D SpyM50429 ABC transporter ATP-binding protein K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1] D SpyM51211 extracellular solute-binding protein K23059 artP; arginine/lysine/histidine transporter system substrate-binding protein D SpyM50614 putative amino acid ABC transporter permease protein K17077 artQ; arginine/lysine/histidine transport system permease protein D SpyM50615 glnQ3; putative glutamine transporter, ATP-binding protein 3 K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1] D SpyM50215 glutamine ABC transporter, glutamine-binding protein/permease protein K17073 lysX1; putative lysine transport system substrate-binding protein D SpyM50214 glnQ2; putative glutamine ABC transporter, ATP-binding protein 2 K17076 lysY; putative lysine transport system ATP-binding protein D SpyM51584 putative lipoprotein K02073 metQ; D-methionine transport system substrate-binding protein D SpyM51582 putative D-methionine transport system permease protein K02072 metI; D-methionine transport system permease protein D SpyM51583 putative D-methionine transport system ATP-binding protein K02071 metN; D-methionine transport system ATP-binding protein D SpyM50227 putative extracellular oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein D SpyM50228 putative oligopeptide transporter permease protein K15581 oppB; oligopeptide transport system permease protein D SpyM50229 putative oligopeptide transporter permease protein K15582 oppC; oligopeptide transport system permease protein D SpyM50230 putative oligopeptide transporter ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein D SpyM50231 putative oligopeptide transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein D SpyM51680 lmb; laminin binding protein K09815 znuA; zinc transport system substrate-binding protein D SpyM51261 adcA; zinc-binding protein AdcA precursor K09815 znuA; zinc transport system substrate-binding protein D SpyM50077 ABC transporter permease protein K09816 znuB; zinc transport system permease protein D SpyM50076 ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D SpyM51497 mtsA; metal ABC transporter substrate-binding lipoprotein precursor K11704 mtsA; iron/zinc/manganese/copper transport system substrate-binding protein D SpyM51495 mtsC; metal cation ABC transporter membrane protein K11705 mtsC; iron/zinc/manganese/copper transport system permease protein D SpyM51496 mtsB; metal cation ABC transporter ATP-binding protein K11706 mtsB; iron/zinc/manganese/copper transport system ATP-binding protein D SpyM50159 BioY family protein K03523 bioY; biotin transport system substrate-specific component D SpyM51816 putative cobalt transport protein K16785 ecfT; energy-coupling factor transport system permease protein D SpyM50324 putative membrane protein K16785 ecfT; energy-coupling factor transport system permease protein D SpyM51818 ABC transporter ATP-binding protein K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D SpyM51817 ABC transporter ATP-binding protein K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D SpyM51331 ftsX; putative cell division protein K09811 ftsX; cell division transport system permease protein D SpyM51332 ftsE; putative cell division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein D SpyM50175 ABC transporter ATP-binding membrane protein K18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump D SpyM50176 ABC transporter ATP-binding membrane protein K18892 patB; ATP-binding cassette, subfamily B, multidrug efflux pump D SpyM50920 ABC transporter ATP-binding membrane protein K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump D SpyM50919 ABC transporter ATP-binding membrane protein K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump C 02060 Phosphotransferase system (PTS) [PATH:spf02060] D SpyM50740 pstI; phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] D SpyM50739 ptsH; histidine-containing phosphocarrier protein (HPr) K02784 ptsH; phosphocarrier protein HPr D SpyM51662 putative glucose-specific phosphotransferase system (PTS), IIABC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208] D SpyM50308 scrA; putative sucrose-specific phosphotransferase system (PTS), IIABC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D SpyM51385 beta-glucoside-specific phosphotransferase system (PTS), IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D SpyM51743 sugar phosphotransferase system (PTS), IIABC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D SpyM51609 lacF; putative lactose-specific phosphotransferase system (PTS), IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D SpyM51608 lacE; putative lactose-specific phosphotransferase system (PTS), IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D SpyM50784 putative lactose/cellobiose-specific phosphotransferase system (PTS), IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D SpyM51709 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D SpyM50783 putative lactose/cellobiose-specific phosphotransferase system (PTS), IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D SpyM51708 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D SpyM51707 sugar phosphotransferase system (PTS), IIC component K02761 celB; cellobiose PTS system EIIC component D SpyM50786 sugar phosphotransferase system (PTS), IIC component K02761 celB; cellobiose PTS system EIIC component D SpyM50986 sugar phosphotransferase system (PTS),mannose/fructose family, IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D SpyM50366 manL; putative mannose-specific phosphotransferase system (PTS), IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D SpyM50365 manM; putative mannose-specific phosphotransferase system (PTS), IIC component K02795 manY; mannose PTS system EIIC component D SpyM50984 sugar phosphotransferase system (PTS),mannose/fructose family, IIC component K02795 manY; mannose PTS system EIIC component D SpyM50364 manN; putative mannose-specific phosphotransferase system (PTS), IID component K02796 manZ; mannose PTS system EIID component D SpyM50983 sugar phosphotransferase system (PTS),mannose/fructose family, IID component K02796 manZ; mannose PTS system EIID component D SpyM50985 sugar phosphotransferase system (PTS),mannose/fructose family, IIB component K19507 gfrB; fructoselysine/glucoselysine PTS system EIIB component [EC:2.7.1.-] D SpyM51340 putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-] D SpyM51342 agaV; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-] D SpyM51343 agaW; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component D SpyM51344 agaD; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component D SpyM50389 sugar phosphotransferase system (PTS), IIA component K20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204] D SpyM50390 sugar phosphotransferase system (PTS), IIB component K20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204] D SpyM50391 sugar phosphotransferase system (PTS),galactitol-specific family, IIC component K20114 gatC; galactose PTS system EIIC component D SpyM50144 sugar phosphotransferase system (PTS), IIA component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D SpyM51637 putative PTS multi-domain regulator K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D SpyM50143 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D SpyM51636 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D SpyM51635 putative sugar-specific permease K03475 ulaA; ascorbate PTS system EIIC component D SpyM50142 putative sugar-specific permease, SgaT/UlaA family K03475 ulaA; ascorbate PTS system EIIC component D SpyM51146 fruA; putative fructose-specific phosphotransferase system (PTS), IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D SpyM51147 fruK; putative 1-phosphofructokinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56] C 03070 Bacterial secretion system [PATH:spf03070] D SpyM51713 putative preprotein translocase SecE subunit K03073 secE; preprotein translocase subunit SecE D SpyM51457 secG; putative protein-export membrane protein K03075 secG; preprotein translocase subunit SecG D SpyM50064 secY; preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY D SpyM51649 putative preprotein translocase subunit K03210 yajC; preprotein translocase subunit YajC D SpyM51561 membrane protein OxaA 2 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase D SpyM50188 membrane protein OxaA 1 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase D SpyM50312 secA; putative preprotein SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D SpyM51388 ftsY; putative cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor D SpyM50883 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] B B 09132 Signal transduction C 02020 Two-component system [PATH:spf02020] D SpyM50843 pstS; putative phosphate ABC transporter,extracellular phosphate-binding lipoprotein K02040 pstS; phosphate transport system substrate-binding protein D SpyM51837 htrA; serine protease K04771 degP; serine protease Do [EC:3.4.21.107] D SpyM51428 vicK; sensor histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] D SpyM51429 vicR; response regulator protein K07668 vicR; two-component system, OmpR family, response regulator VicR D SpyM50001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein D SpyM50792 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D SpyM50793 dltB; putative activated D-alanine transport protein K03739 dltB; membrane protein involved in D-alanine export D SpyM50794 dltC; D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D SpyM50795 dltD; putative D-alanyl-lipoteichoic acid biosynthesis protein K03740 dltD; D-alanine transfer protein D SpyM50851 ciaH; sensor histidine kinase K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3] D SpyM50850 ciaR; response regulator protein K14983 ciaR; two-component system, OmpR family, response regulator CiaR D SpyM50343 putative D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D SpyM51572 csrS; sensor histidine kinase K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3] D SpyM51573 csrR; response regulator protein K18941 arlR; two-component system, OmpR family, response regulator ArlR D SpyM51687 sensor histidine kinase K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3] D SpyM51688 response regulator protein K18987 irr; two-component system, OmpR family, response regulator Irr D SpyM50887 citC; putative Citrate [pro-3S]-lyase] ligase K01910 citC; [citrate (pro-3S)-lyase] ligase [EC:6.2.1.22] D SpyM50892 citD; putative citrate lyase acyl carrier protein K01646 citD; citrate lyase subunit gamma (acyl carrier protein) D SpyM50891 citE; putative citrate lyase beta subunit K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34] D SpyM50890 citF; putative citrate lyase alpha subunit K01643 citF; citrate lyase subunit alpha / citrate CoA-transferase [EC:2.8.3.10] D SpyM50889 citX; puatative apo-citrate lyase phosphoribosyl-dephospho-CoA transferase K05964 citX; holo-ACP synthase [EC:2.7.7.61] D SpyM50899 citG; putative 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52] D SpyM50955 NAD-dependent malic enzyme K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D SpyM50956 malP; sodium-dependent malate transporter K11616 maeN; malate:Na+ symporter D SpyM50537 putative sensor kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D SpyM50183 fasB; sensor histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D SpyM50186 fasA; response regulator protein K07707 agrA; two-component system, LytTR family, response regulator AgrA D SpyM50236 comX1; putative competence-specific global transcription modulator K12296 comX1_2; competence protein ComX D SpyM51595 comX2; putative competence-specific global transcription modulator 2 K12296 comX1_2; competence protein ComX D SpyM50010 putative exported protein K01467 ampC; beta-lactamase class C [EC:3.5.2.6] D SpyM50458 sensor histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3] D SpyM50459 response regulator protein K11618 liaR; two-component system, NarL family, response regulator LiaR D SpyM51602 salK; sensor histidine kinase K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK D SpyM51601 salR; response regulator protein K14989 salR; two-component system, NarL family, secretion system response regulator SalR D SpyM50255 glnA; putative glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D SpyM50115 atoD1; acetate CoA-transferase alpha subunit 1 K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D SpyM50446 atoD2; acetate CoA-transferase alpha subunit 2 K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D SpyM50116 atoA1; acetate CoA-transferase beta subunit 1 K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] D SpyM50112 putative short-chain fatty acids transporter K02106 atoE; short-chain fatty acids transporter D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM50549 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D SpyM50572 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D SpyM50981 response regulator protein K07720 yesN; two-component system, response regulator YesN D SpyM50550 response regulator protein K07720 yesN; two-component system, response regulator YesN D SpyM50036 putative phosphotyrosine protein phosphatase K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:spf02024] D SpyM50442 luxS; S-ribosylhomocysteinase K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21] D SpyM51668 trpG; anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D SpyM51431 hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D SpyM50537 putative sensor kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D SpyM50183 fasB; sensor histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D SpyM50186 fasA; response regulator protein K07707 agrA; two-component system, LytTR family, response regulator AgrA D SpyM50136 slo; streptolysin O precursor (thiol-activated cytolysin) K11031 slo; thiol-activated cytolysin D SpyM50851 ciaH; sensor histidine kinase K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3] D SpyM50850 ciaR; response regulator protein K14983 ciaR; two-component system, OmpR family, response regulator CiaR D SpyM50227 putative extracellular oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein D SpyM50228 putative oligopeptide transporter permease protein K15581 oppB; oligopeptide transport system permease protein D SpyM50229 putative oligopeptide transporter permease protein K15582 oppC; oligopeptide transport system permease protein D SpyM50230 putative oligopeptide transporter ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein D SpyM50231 putative oligopeptide transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein D SpyM50034 putative DNA-binding protein K20342 comR; HTH-type transcriptional regulator, regulator for ComX D SpyM50236 comX1; putative competence-specific global transcription modulator K12296 comX1_2; competence protein ComX D SpyM51595 comX2; putative competence-specific global transcription modulator 2 K12296 comX1_2; competence protein ComX D SpyM51462 putative DNA-binding protein K20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator D SpyM51424 putative regulatory protein K20374 rgg3; HTH-type transcriptional regulator, SHP3-responsive repressor D SpyM51673 dppA; dipeptide-binding extracellular protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D SpyM51674 dppB; dipeptide transport system permease protein DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein D SpyM51675 dppC; dipeptide transport system permease protein DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein D SpyM51676 dppD; dipeptide transport system ATP-binding protein DppD K02031 ddpD; peptide/nickel transport system ATP-binding protein D SpyM51677 dppE; dipeptide transport system ATP-binding protein DppF K02032 ddpF; peptide/nickel transport system ATP-binding protein D SpyM51701 ropB; transcriptional regulator K20375 ropB; HTH-type transcriptional regulator, pheromone-responsive regulator D SpyM51698 speB; Streptopain precursor K01364 speB; streptopain [EC:3.4.22.10] D SpyM50395 lacD1; tagatose 1,6-diphosphate aldolase 1 K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40] D SpyM51610 lacD2; tagatose 1,6-diphosphate aldolase 2 K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40] D SpyM51561 membrane protein OxaA 2 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase D SpyM50188 membrane protein OxaA 1 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase D SpyM51713 putative preprotein translocase SecE subunit K03073 secE; preprotein translocase subunit SecE D SpyM51457 secG; putative protein-export membrane protein K03075 secG; preprotein translocase subunit SecG D SpyM50064 secY; preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY D SpyM51649 putative preprotein translocase subunit K03210 yajC; preprotein translocase subunit YajC D SpyM50312 secA; putative preprotein SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D SpyM51388 ftsY; putative cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor D SpyM50883 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis C 02040 Flagellar assembly [PATH:spf02040] D SpyM51102 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D SpyM51585 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D SpyM51207 rpoD; RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D SpyM51248 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells D SpyM50104 putative surface-anchored protein K13734 sfb1; fibronectin-binding protein 1 D SpyM50110 protein F2 like fibronectin-binding protein K13734 sfb1; fibronectin-binding protein 1 B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance [PATH:spf01501] D SpyM50010 putative exported protein K01467 ampC; beta-lactamase class C [EC:3.5.2.6] D SpyM50227 putative extracellular oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein D SpyM50228 putative oligopeptide transporter permease protein K15581 oppB; oligopeptide transport system permease protein D SpyM50229 putative oligopeptide transporter permease protein K15582 oppC; oligopeptide transport system permease protein D SpyM50230 putative oligopeptide transporter ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein D SpyM50231 putative oligopeptide transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein D SpyM50436 pbp1A; putative penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D SpyM50080 pbp1B; putative penicillin-binding protein 1B K03693 pbp1b; penicillin-binding protein 1B D SpyM51715 pbp2A; penicillin-binding protein 2a K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] D SpyM50425 pbpX; putative penicillin binding protein 2x K12556 pbp2X; penicillin-binding protein 2X C 01502 Vancomycin resistance [PATH:spf01502] D SpyM50702 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D SpyM50314 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D SpyM50703 murF; putative UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D SpyM50426 mraY; phospho-N-acetylmuramoyl-pentapeptide-transfera se K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D SpyM50600 murG; putative UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyr ophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D SpyM50343 putative D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:spf01503] D SpyM51837 htrA; serine protease K04771 degP; serine protease Do [EC:3.4.21.107] D SpyM51494 putative cyclophilin type peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D SpyM50792 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D SpyM50793 dltB; putative activated D-alanine transport protein K03739 dltB; membrane protein involved in D-alanine export D SpyM50794 dltC; D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D SpyM50795 dltD; putative D-alanyl-lipoteichoic acid biosynthesis protein K03740 dltD; D-alanine transfer protein D SpyM51698 speB; Streptopain precursor K01364 speB; streptopain [EC:3.4.22.10] B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:spf01000] C 01001 Protein kinases [BR:spf01001] D SpyM50456 stk1; serine/threonine-protein kinase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] D SpyM51428 vicK; sensor histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] D SpyM50851 ciaH; sensor histidine kinase K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3] D SpyM51572 csrS; sensor histidine kinase K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3] D SpyM51687 sensor histidine kinase K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3] D SpyM50458 sensor histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3] D SpyM51602 salK; sensor histidine kinase K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK D SpyM50957 putative sensor kinase K02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3] D SpyM50537 putative sensor kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D SpyM50183 fasB; sensor histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D SpyM50549 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D SpyM50572 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C 01009 Protein phosphatases and associated proteins [BR:spf01009] D SpyM50812 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D SpyM50455 putative protein phosphatase K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16] C 01002 Peptidases and inhibitors [BR:spf01002] D SpyM51170 lspA; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] D SpyM50435 pepC; aminopeptidase C K01372 BLMH; bleomycin hydrolase [EC:3.4.22.40] D SpyM51698 speB; Streptopain precursor K01364 speB; streptopain [EC:3.4.22.10] D SpyM51453 pcp; pyrrolidone-carboxylate peptidase K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3] D SpyM50879 guaA; GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D SpyM50947 putative peptidase K07010 K07010; putative glutamine amidotransferase D SpyM50015 putative amidase K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] D SpyM50023 purF; putative amidophosphoribosyltransferase precursor K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D SpyM50815 glmS; glucosamine--fructose-6-phosphate aminotransferase [isomerizing] K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D SpyM50915 srtA; sortase A K07284 srtA; sortase A [EC:3.4.22.70] D SpyM50107 srtB; sortase B K08600 srtB; sortase B [EC:3.4.22.71] D SpyM50730 CAAX amino terminal protease family membrane protein K07052 K07052; CAAX protease family protein D SpyM51243 sagE; CAAX amino terminal protease family protein K07052 K07052; CAAX protease family protein D SpyM50849 pepN; putative lysyl-aminopeptidase K01256 pepN; aminopeptidase N [EC:3.4.11.2] D SpyM50722 pepB; putative oligopeptidase K08602 pepF; oligoendopeptidase F [EC:3.4.24.-] D SpyM51741 pepO; putative endopeptidase O K07386 pepO; putative endopeptidase [EC:3.4.24.-] D SpyM50343 putative D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D SpyM50976 pepV; putative Xaa-His dipeptidase K01274 pepV; beta-Ala-Xaa dipeptidase [EC:3.4.13.-] D SpyM51192 pepT; peptidase T K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] D SpyM50756 putative metallopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D SpyM51447 pepQ; putative Xaa-Pro dipeptidase K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9] D SpyM50301 putative metallopeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] D SpyM50013 ftsH; putative cell division protease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D SpyM50095 pepA; putative glutamyl-aminopeptidase K01261 pepA; glutamyl aminopeptidase [EC:3.4.11.7] D SpyM51575 htpX; probable protease HtpX homolog K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D SpyM51646 eep; putative pheromone-processing membrane metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] D SpyM51837 htrA; serine protease K04771 degP; serine protease Do [EC:3.4.21.107] D SpyM51518 prtS; putative cell surface protease K01361 E3.4.21.96; lactocepin [EC:3.4.21.96] D SpyM51681 scpA; C5A peptidase precursor K08652 C5AP; C5a peptidase [EC:3.4.21.110] D SpyM50971 putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D SpyM50226 putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D SpyM51530 clpP; putative ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D SpyM50273 pepXP; Xaa-Pro dipeptidyl-peptidase K01281 pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11] D SpyM50587 putative exported protein K07177 K07177; Lon-like protease D SpyM50884 putative phage repressor-like protein K01356 lexA; repressor LexA [EC:3.4.21.88] D SpyM50285 spi; putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D SpyM50814 sipC; putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D SpyM50105 putative signal peptidase K03100 lepB; signal peptidase I [EC:3.4.21.89] D SpyM51397 putative microcin immunity protein K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13] D SpyM51371 putative peptidase K08303 prtC; U32 family peptidase [EC:3.4.-.-] C 01003 Glycosyltransferases [BR:spf01003] D SpyM51444 putative glycosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D SpyM51824 hasA; hyaluronan synthase K00752 hasA; hyaluronan synthase [EC:2.4.1.212] D SpyM51445 putative glycosyltransferase K13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208] D SpyM50436 pbp1A; putative penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D SpyM50080 pbp1B; putative penicillin-binding protein 1B K03693 pbp1b; penicillin-binding protein 1B D SpyM51715 pbp2A; penicillin-binding protein 2a K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] D SpyM50219 rgpG; putative glycosyl transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] C 01005 Lipopolysaccharide biosynthesis proteins [BR:spf01005] D SpyM51203 putative rhamnosyltransferase K12996 rgpA; rhamnosyltransferase [EC:2.4.1.-] D SpyM51202 putative glycosyltransferase K12997 rgpB; rhamnosyltransferase [EC:2.4.1.-] D SpyM51199 putative glycosyltransferase K12998 rgpE; glucosyltransferase [EC:2.4.1.-] D SpyM51198 rhamnan synthesis protein F family protein K07272 rgpF; rhamnosyltransferase [EC:2.4.1.-] D SpyM50219 rgpG; putative glycosyl transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D SpyM51450 csbB; putative glucosyl transferase K12999 rgpI; glucosyltransferase [EC:2.4.1.-] C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:spf01011] D SpyM51224 murA1; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D SpyM50752 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D SpyM50963 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D SpyM51565 murC; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D SpyM50599 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D SpyM51533 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-dia minopimelate ligase K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7] D SpyM50702 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D SpyM50878 murM; putative peptidoglycan branched peptide synthesis protein MurM K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10] D SpyM51352 murM; putative peptidoglycan pentaglycine interpeptide biosynthesis protein K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10] D SpyM51353 murN; putative peptidoglycan branched peptide synthesis protein K12554 murN; alanine adding enzyme [EC:2.3.2.-] D SpyM50314 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D SpyM51555 glr; glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D SpyM51397 putative microcin immunity protein K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13] D SpyM50426 mraY; phospho-N-acetylmuramoyl-pentapeptide-transfera se K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D SpyM50600 murG; putative UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyr ophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D SpyM50217 bacA; undecaprenol kinase (bacitracin resistance protein) K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D SpyM51544 PAP2 superfamily protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D SpyM50436 pbp1A; putative penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D SpyM50080 pbp1B; putative penicillin-binding protein 1B K03693 pbp1b; penicillin-binding protein 1B D SpyM51715 pbp2A; penicillin-binding protein 2a K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] D SpyM50425 pbpX; putative penicillin binding protein 2x K12556 pbp2X; penicillin-binding protein 2X D SpyM50971 putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D SpyM50226 putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D SpyM50343 putative D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D SpyM50015 putative amidase K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] D SpyM50915 srtA; sortase A K07284 srtA; sortase A [EC:3.4.22.70] D SpyM50107 srtB; sortase B K08600 srtB; sortase B [EC:3.4.22.71] D SpyM51563 putative aminodeoxychorismate lyase K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] C 01004 Lipid biosynthesis proteins [BR:spf01004] D SpyM50354 fabD; putative malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D SpyM50351 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D SpyM50356 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D SpyM51506 putative short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SpyM50355 fabG; 3-oxoacyl-[acyl-carrier protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SpyM50358 fabZ; (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D SpyM50353 fabK; enoyl-ACP reductase K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9] D SpyM50349 enoyl-CoA hydratase/isomerase family protein K18474 fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14] D SpyM51431 hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D SpyM50018 plsX; fatty acid/phospholipid synthesis protein K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D SpyM51098 putative membrane protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D SpyM50710 putative acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases [BR:spf01006] D SpyM50622 fps; putative geranyltranstransferase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29] D SpyM51648 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D SpyM51085 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] C 01007 Amino acid related enzymes [BR:spf01007] D SpyM50182 gltX; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D SpyM50079 tyrS; putative tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D SpyM51831 trsA; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D SpyM51628 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D SpyM51783 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D SpyM51515 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D SpyM50609 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D SpyM50564 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D SpyM50141 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D SpyM51368 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D SpyM51788 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D SpyM51326 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D SpyM51789 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D SpyM50405 glyQ; glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D SpyM50406 glyS; glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D SpyM50362 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D SpyM51645 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D SpyM51443 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D SpyM50726 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D SpyM51220 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D SpyM51219 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D SpyM50332 putative aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D SpyM51094 putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D SpyM51667 putative chorismate binding enzyme K03342 pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins [BR:spf00194] D SpyM51226 atpC; ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D SpyM51227 atpD; ATP synthase beta chain K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D SpyM51228 atpG; ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D SpyM51229 atpA; ATP synthase alpha chain K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D SpyM51230 atpH; putative ATP synthase delta chain K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D SpyM51231 atpF; ATP synthase B chain K02109 ATPF0B; F-type H+-transporting ATPase subunit b D SpyM51233 atpE; ATP synthase C chain K02110 ATPF0C; F-type H+-transporting ATPase subunit c D SpyM51232 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:spf03000] D SpyM51614 lacR2; lactose phosphotransferase system repressor 2 K02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor D SpyM50388 lacR1; lactose phosphotransferase system repressor 1 K02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor D SpyM51148 DeoR family regulatory protein K03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor D SpyM50588 LacI family regulatory protein K02529 galR; LacI family transcriptional regulator, galactose operon repressor D SpyM50803 LacI family transcriptional repressor K02529 galR; LacI family transcriptional regulator, galactose operon repressor D SpyM51446 ccpA; catabolite control protein A K02529 galR; LacI family transcriptional regulator, galactose operon repressor D SpyM51346 LacI family regulatory protein K02525 kdgR; LacI family transcriptional regulator, kdg operon repressor D SpyM50306 scrR; putative sucrose operon repressor K03484 scrR; LacI family transcriptional regulator, sucrose operon repressor D SpyM50540 GntR family regulatory protein K02103 araR; GntR family transcriptional regulator, arabinose operon transcriptional repressor D SpyM51744 GntR family regulatory protein K03486 treR2; GntR family transcriptional regulator, trehalose operon transcriptional repressor D SpyM50881 GntR family regulatory protein K24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator D SpyM51260 GntR family regulatory protein K24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator D SpyM50254 glnR; MerR family regulatory protein K03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor D SpyM50154 ferric uptake regulator family protein K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator D SpyM50576 Crp family regulatory protein K21828 arcR; CRP/FNR family transcriptional regulator, arginine deiminase pathway regulator D SpyM51793 cadC; putative cadmium efflux system accessory protein K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor D SpyM51800A PadR family regulatory protein K10947 K10947; PadR family transcriptional regulator D SpyM51498 scaR; metal-dependent transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D SpyM50749 birA; BirA bifunctional protein [includes: biotin operon repressor; biotin--[acetyl-CoA-carboxylase] synthetase] K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D SpyM50034 putative DNA-binding protein K20342 comR; HTH-type transcriptional regulator, regulator for ComX D SpyM51462 putative DNA-binding protein K20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator D SpyM51424 putative regulatory protein K20374 rgg3; HTH-type transcriptional regulator, SHP3-responsive repressor D SpyM51701 ropB; transcriptional regulator K20375 ropB; HTH-type transcriptional regulator, pheromone-responsive regulator D SpyM50207 purR; putative pur operon repressor K09685 purR; HTH-type transcriptional regulator, purine operon repressor D SpyM50946 rex; putative redox-sensing transcriptional repressor K01926 rex; redox-sensing transcriptional repressor D SpyM50333 codY; GTP-sensing transcriptional pleiotropic repressor K03706 codY; transcriptional pleiotropic repressor D SpyM50478 putative DNA-binding phage protein K07727 K07727; putative transcriptional regulator D SpyM51621 putative DNA-binding protein K07729 K07729; putative transcriptional regulator D SpyM50728 putative DNA-binding protein K07729 K07729; putative transcriptional regulator D SpyM51317 putative phage repressor protein K07729 K07729; putative transcriptional regulator D SpyM51386 licT; transcription antiterminator K03488 licT; beta-glucoside operon transcriptional antiterminator D SpyM50148 putative transcriptional antiterminator K03493 bglG1; transcriptional antiterminator D SpyM50782 putative regulatory protein K03491 licR; probable licABCH operon transcriptional regulator D SpyM51838 putative chromosome partitioning protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D SpyM50575 argR; arginine repressor K03402 argR; transcriptional regulator of arginine metabolism D SpyM50624 putative repressor protein K03402 argR; transcriptional regulator of arginine metabolism D SpyM51782 argR; putative arginine repressor K03402 argR; transcriptional regulator of arginine metabolism D SpyM50345 hrcA; heat-inducible transcription repressor HrcA K03705 hrcA; heat-inducible transcriptional repressor D SpyM51724 ctsR; transcriptional regulator K03708 ctsR; transcriptional regulator of stress and heat shock response D SpyM51168 pyrR; PyrR bifunctional protein [includes: pyrimidine operon regulatory protein; uracil phosphoribosyltransferase] K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9] D SpyM51571 ATP-binding protein K07738 nrdR; transcriptional repressor NrdR D SpyM50236 comX1; putative competence-specific global transcription modulator K12296 comX1_2; competence protein ComX D SpyM51595 comX2; putative competence-specific global transcription modulator 2 K12296 comX1_2; competence protein ComX C 03021 Transcription machinery [BR:spf03021] D SpyM50069 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D SpyM50081 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D SpyM50082 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D SpyM50243 rpoE; putative DNA-directed RNA polymerase, delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta D SpyM50451 rpoZ; DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D SpyM51207 rpoD; RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor D SpyM50379 nusA; putative N utilization substance protein A K02600 nusA; transcription termination/antitermination protein NusA D SpyM50305 nusB; N utilization substance protein B homolog (NusB protein) K03625 nusB; transcription antitermination protein NusB D SpyM50133 nusG; transcription antitermination factor K02601 nusG; transcription termination/antitermination protein NusG D SpyM51562 greA; transcription elongation factor K03624 greA; transcription elongation factor GreA C 03019 Messenger RNA biogenesis [BR:spf03019] D SpyM51426 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D SpyM50256 metallo-beta-lactamase superfamily protein K12574 rnj; ribonuclease J [EC:3.1.-.-] D SpyM51012 metallo-beta-lactamase superfamily protein K12574 rnj; ribonuclease J [EC:3.1.-.-] D SpyM50449 putative phosphohydrolase K18682 rny; ribonucrease Y [EC:3.1.-.-] D SpyM51456 rnr; putative exoribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1] D SpyM50206 putative 3'-5' exoribonuclease K03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-] D SpyM50706 DEAD box helicase family protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D SpyM50427 mraW; putative helicase K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7] D SpyM51248 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D SpyM51633 pnpA; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D SpyM50812 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D SpyM50347 dnaK; chaperone protein DnaK (heat shock protein 70) K04043 dnaK; molecular chaperone DnaK D SpyM51721 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D SpyM51325 P-loop ATPase protein family protein K06958 rapZ; RNase adapter protein RapZ C 03041 Spliceosome C 03011 Ribosome [BR:spf03011] D SpyM51092 putative 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1 D SpyM51739 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D SpyM50050 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D SpyM51805 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D SpyM50061 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D SpyM50295 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6 D SpyM50210 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D SpyM50058 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D SpyM51619 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D SpyM50043 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D SpyM50068 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D SpyM50209 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D SpyM50067 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D SpyM50057 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D SpyM50261 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D SpyM51638 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D SpyM51159 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D SpyM50053 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D SpyM50297 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D SpyM50048 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D SpyM50852 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20 D SpyM51210 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D SpyM51490 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D SpyM50047 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D SpyM50044 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D SpyM50045 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4 D SpyM50056 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D SpyM50059 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D SpyM51808 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9 D SpyM50973 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D SpyM51491 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D SpyM50972 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D SpyM51620 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D SpyM50054 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D SpyM50063 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D SpyM50051 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D SpyM50070 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D SpyM50060 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D SpyM51253 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D SpyM51186 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D SpyM51174 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D SpyM50049 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D SpyM50046 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D SpyM50055 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D SpyM51172 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D SpyM50247 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D SpyM50052 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D SpyM50062 rpmD; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D SpyM51258 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D SpyM51790 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D SpyM51714 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D SpyM51791 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D SpyM51458A rpmGB; 50S ribosomal protein L33 2 K02913 RP-L33; large subunit ribosomal protein L33 D SpyM50190 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34 D SpyM51187 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35 D SpyM50066A rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36 D 5S_rRNA-1 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D 5S_rRNA-3 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D 5S_rRNA-2 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D 5S_rRNA-4 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D 5S_rRNA-5 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D 5S_rRNA-6 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D 16S_rRNA-1 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 16S_rRNA-3 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 16S_rRNA-6 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 16S_rRNA-2 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 16S_rRNA-4 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 16S_rRNA-5 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 23S_rRNA-2 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 23S_rRNA-1 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 23S_rRNA-3 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 23S_rRNA-4 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 23S_rRNA-5 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 23S_rRNA-6 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 03009 Ribosome biogenesis [BR:spf03009] D SpyM51426 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D SpyM51478 era; GTP-binding protein Era homolog K03595 era; GTPase D SpyM50777 putative GTP-binding protein K03979 obgE; GTPase [EC:3.6.5.-] D SpyM50379 nusA; putative N utilization substance protein A K02600 nusA; transcription termination/antitermination protein NusA D SpyM50305 nusB; N utilization substance protein B homolog (NusB protein) K03625 nusB; transcription antitermination protein NusB D SpyM50133 nusG; transcription antitermination factor K02601 nusG; transcription termination/antitermination protein NusG D SpyM50719 putative ribosomal small subunit pseudouridine synthase A K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19] D SpyM50768 putative ribosomal small subunit pseudouridine synthase B K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19] D SpyM50201 ksgA; dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D SpyM50454 putative ribosomal RNA small subunit methyltransferase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D SpyM50854 putative methyltransferase K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172] D SpyM50585 putative methylase K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171] D SpyM51663 conserved hypothetical protein K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193] D SpyM51577 gidB; methyltransferase GidB K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D SpyM50423 mraW; S-adenosyl-methyltransferase MraW K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199] D SpyM51524 tetrapyrrole (corrin/porphyrin) methylase family protein K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198] D SpyM50623 hemolysin-like protein K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227] D SpyM51625 SpoU rRNA methylase family protein K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185] D SpyM51836 conserved hypothetical protein K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177] D SpyM51184 conserved hypothetical protein K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191] D SpyM50591 radical SAM superfamily protein K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192] D SpyM50761 putative RNA methyltransferase K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190] D SpyM51548 rluB; ribosomal large subunit pseudouridine synthase B K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22] D SpyM51169 putative RNA pseudouridylate synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D SpyM50939 putative RNA pseudouridylate synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D SpyM51717 RNA pseudouridylate synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D SpyM50259 acetyltransferase (GNAT) family protein K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D SpyM51153 rimM; 16S rRNA processing protein K02860 rimM; 16S rRNA processing protein RimM D SpyM51664 ribosomal protein L11 methyltransferase K02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-] D SpyM51755 putative Holliday junction resolvase K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-] D SpyM51627 conserved hypothetical protein K11145 mrnC; mini-ribonuclease III [EC:3.1.26.-] D SpyM50706 DEAD box helicase family protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D SpyM50427 mraW; putative helicase K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7] D SpyM50202 engC; probable GTPase EngC K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D SpyM51568 engA; GTP-binding protein EngA K03977 engA; GTPase D SpyM50908 putative GTPase protein K14540 rbgA; ribosome biogenesis GTPase A D SpyM51084 putative GTPase K03665 hflX; GTPase D SpyM51593 GTP-binding protein K06948 yqeH; 30S ribosome assembly GTPase D SpyM50925 conserved hypothetical protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D SpyM51658 relA; GTP pyrophosphokinase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D SpyM50383 rbfA; ribosome-binding factor A K02834 rbfA; ribosome-binding factor A D SpyM50378 conserved hypothetical protein K09748 rimP; ribosome maturation factor RimP D SpyM51827 conserved hypothetical protein K14761 rlbA; ribosome-associated protein D SpyM51589 conserved hypothetical protein K09710 ybeB; ribosome-associated protein D SpyM51480 conserved hypothetical protein K07042 ybeY; probable rRNA maturation factor D SpyM51592 conserved hypothetical protein K07574 yhbY; RNA-binding protein D SpyM50466 sigma 54 modulation protein / S30EA ribosomal protein K05808 hpf; ribosome hibernation promoting factor D SpyM50004 putative GTP-binding protein K06942 ychF; ribosome-binding ATPase D SpyM51574 conserved hypothetical protein K07040 yceD; DUF177 domain-containing protein C 03016 Transfer RNA biogenesis [BR:spf03016] D SpyM51082 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11] D SpyM51134 cca; CCA-adding enzyme K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] D SpyM51645 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D SpyM50609 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D SpyM50141 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D SpyM51515 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D SpyM51783 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D SpyM51368 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D SpyM51788 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D SpyM50726 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D SpyM51326 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D SpyM51443 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D SpyM50362 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D SpyM51628 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D SpyM50564 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D SpyM51789 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D SpyM51220 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D SpyM51219 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D SpyM50079 tyrS; putative tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D SpyM51831 trsA; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D SpyM51657 D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96] D SpyM50373 HIT-family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D SpyM50377 tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] D SpyM50237 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D SpyM50837 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D SpyM51177 putative cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D SpyM50944 putative cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D SpyM50925 conserved hypothetical protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D SpyM51085 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D SpyM50975 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-] D SpyM51810 gidA; glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D SpyM50187 rnpA; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5] D SpyM50405 glyQ; glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D SpyM50406 glyS; glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D SpyM50182 gltX; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D SpyM51365 conserved hypothetical protein K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-] D SpyM50161 putative deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33] D SpyM50101 putative tRNA-dihydrouridine synthase K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-] D SpyM50904 protein Gid homolog K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74] D SpyM51152 trmD; tRNA (Guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D SpyM51076 conserved hypothetical protein K06967 trmK; tRNA (adenine22-N1)-methyltransferase [EC:2.1.1.217] D SpyM51546 SpoU rRNA methylase family protein K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207] D SpyM51559 SpoU rRNA Methylase family protein K03437 spoU; RNA methyltransferase, TrmH family D SpyM51812 putative tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D SpyM50717 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17] D SpyM51334 putative iron-sulphur protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6] D SpyM50177 conserved hypothetical protein K09765 queH; epoxyqueuosine reductase [EC:1.17.99.6] D SpyM50157 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29] D SpyM51176 thiI; putative thiamine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D SpyM50011 PP-loop family protein K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19] D SpyM50258 glycoprotease family protein K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB D SpyM50260 putative glycoprotease K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234] D SpyM50369 putative P-loop hydrolase K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE D SpyM51587 conserved hypothetical protein K27343 tmcAL; tRNA(Met) cytidine acetate ligase [EC:6.3.4.-] D SpyM51456 rnr; putative exoribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1] D SpyM51633 pnpA; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] C 03012 Translation factors [BR:spf03012] D SpyM50382 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2 D SpyM51188 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D SpyM51009 ABC transporter ATP-binding protein K06158 ABCF3; ATP-binding cassette, subfamily F, member 3 D SpyM51740 tsf; elongation factor Ts K02357 tsf; elongation factor Ts D SpyM51355 tufA; elongation factor Tu (EF-Tu) K02358 tuf; elongation factor Tu D SpyM50211 fus; elongation factor G (EF-G) K02355 fusA; elongation factor G D SpyM50927 prfA; peptide chain release factor 1 K02835 prfA; peptide chain release factor 1 D SpyM51488 rrf; ribosome recycling factor K02838 frr; ribosome recycling factor D SpyM50926 putative methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D SpyM50005 pth; peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] D SpyM50066 infA; translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1 D SpyM50303 efp; elongation factor P (EF-P) K02356 efp; elongation factor P D SpyM51333 prfB; peptide chain release factor 2 K02836 prfB; peptide chain release factor 2 D SpyM50705 prfC; peptide chain release factor 3 K02837 prfC; peptide chain release factor 3 C 03110 Chaperones and folding catalysts [BR:spf03110] D SpyM51723 clpC; putative stress response-related Clp ATPase K03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC D SpyM50612 clpE; putative ATP-dependent Clp protease ATP-binding subunit K03697 clpE; ATP-dependent Clp protease ATP-binding subunit ClpE D SpyM51114 clpL; putative ATP-dependent protease ATP-binding subunit ClpL K04086 clpL; ATP-dependent Clp protease ATP-binding subunit ClpL D SpyM51117 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX D SpyM50347 dnaK; chaperone protein DnaK (heat shock protein 70) K04043 dnaK; molecular chaperone DnaK D SpyM51721 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D SpyM50348 dnaJ; chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ D SpyM50102 33 kDa chaperonin (heat shock protein 33 homolog) K04083 hslO; molecular chaperone Hsp33 D SpyM50346 grpE; GrpE protein (HSP-70 cofactor) K03687 GRPE; molecular chaperone GrpE D SpyM51722 groES; 10 kDa chaperonin K04078 groES; chaperonin GroES D SpyM51837 htrA; serine protease K04771 degP; serine protease Do [EC:3.4.21.107] D SpyM50013 ftsH; putative cell division protease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D SpyM51232 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a D SpyM51518 prtS; putative cell surface protease K01361 E3.4.21.96; lactocepin [EC:3.4.21.96] D SpyM51681 scpA; C5A peptidase precursor K08652 C5AP; C5a peptidase [EC:3.4.21.110] D SpyM51494 putative cyclophilin type peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D SpyM50460 cyclophilin type peptidyl-prolyl cis-trans isomerase protein K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] D SpyM51695 prsA2; foldase protein PrsA 2 precursor K07533 prsA; foldase protein PrsA [EC:5.2.1.8] D SpyM50725 prsA1; foldase protein PrsA 1 precursor K07533 prsA; foldase protein PrsA [EC:5.2.1.8] D SpyM50291 putative thioredoxin K03671 TXN; thioredoxin C 04131 Membrane trafficking [BR:spf04131] D SpyM50538 glycosyl hydrolases family protein K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24] D SpyM50212 plr; glyceraldehyde-3-phosphate dehydrogenase,plasmin receptor K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D SpyM50696 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D SpyM50813 pyk; putative pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] C 04121 Ubiquitin system C 03051 Proteasome C 03032 DNA replication proteins [BR:spf03032] D SpyM50630 hlpA; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta D SpyM50001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein D SpyM51807 dnaC; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D SpyM50482 putative phage DNA replication protein K02315 dnaC; DNA replication protein DnaC D SpyM51208 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D SpyM51570 replication initiation and membrane attachment protein K03346 dnaB; replication initiation and membrane attachment protein D SpyM51569 dnaI; putative primosomal protein K11144 dnaI; primosomal protein DnaI D SpyM50296 ssb; single strand binding protein (SSB) K03111 ssb; single-strand DNA-binding protein D SpyM50099 putative single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D SpyM50811 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D SpyM51644 polC; DNA polymerase III PolC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D SpyM50002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D SpyM50713 putative DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D SpyM51527 holB; putative DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D SpyM50268 putative exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SpyM50748 dnaH; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D SpyM50907 rnh; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D SpyM50286 ribonuclease HIII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4] D SpyM50152 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D SpyM51235 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D SpyM50916 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D SpyM51251 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D SpyM51095 parC; topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D SpyM51097 parE; topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D SpyM50905 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] C 03036 Chromosome and associated proteins [BR:spf03036] D SpyM51426 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D SpyM50630 hlpA; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta D SpyM50001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein D SpyM50593 dpr; Dps-like peroxide resistance protein Dpr K04047 dps; starvation-inducible DNA-binding protein D SpyM51425 smc; putative chromosome partition protein K03529 smc; chromosome segregation protein D SpyM51550 scpA; segregation and condensation protein A K05896 scpA; segregation and condensation protein A D SpyM51549 scpB; segregation and condensation protein B K06024 scpB; segregation and condensation protein B D SpyM50602 ftsA; putative cell division protein K03590 ftsA; cell division protein FtsA D SpyM50008 putative septum formation initiator protein K13052 divIC; cell division protein DivIC D SpyM51332 ftsE; putative cell division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein D SpyM51493 DNA translocase FtsK K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family D SpyM50424 ftsL; putative cell division protein K03586 ftsL; cell division protein FtsL D SpyM50601 putative cell division protein K03589 ftsQ; cell division protein FtsQ D SpyM51357 ftsW; putative cell division protein K03588 ftsW; cell division protein FtsW D SpyM51331 ftsX; putative cell division protein K09811 ftsX; cell division transport system permease protein D SpyM50603 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D SpyM51250 ezrA; septation ring formation regulator K06286 ezrA; septation ring formation regulator D SpyM50608 putative cell-division protein DivIVA K04074 divIVA; cell division initiation protein D SpyM50605 conserved hypothetical protein K09772 sepF; cell division inhibitor SepF D SpyM51838 putative chromosome partitioning protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D SpyM51095 parC; topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D SpyM51097 parE; topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D SpyM51810 gidA; glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D SpyM51577 gidB; methyltransferase GidB K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D SpyM50904 protein Gid homolog K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74] D SpyM51116 engB; putative GTP-binding protein K03978 engB; GTP-binding protein D SpyM51323 conserved hypothetical protein K09762 whiA; cell division protein WhiA C 03400 DNA repair and recombination proteins [BR:spf03400] D SpyM50616 phr; putative deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D SpyM51100 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D SpyM50293 putative A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D SpyM51077 nth; putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D SpyM51020 mutX; mutator MutX protein (7,8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SpyM50611 Mut/NUDIX family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SpyM50178 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D SpyM51760 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D SpyM51461 fpg; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D SpyM51520 exoA; exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D SpyM51080 putative single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D SpyM51235 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D SpyM50152 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D SpyM50300 uvrA; UvrABC system protein A (UvrA protein) K03701 uvrA; excinuclease ABC subunit A D SpyM50790 uvrB; UvrABC system protein B (UvrB protein) K03702 uvrB; excinuclease ABC subunit B D SpyM50978 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C D SpyM50823 pcrA; putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D SpyM50081 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D SpyM50082 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D SpyM50069 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D SpyM50243 rpoE; putative DNA-directed RNA polymerase, delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta D SpyM50451 rpoZ; DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D SpyM50006 trcF; putative transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D SpyM51780 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS D SpyM50289 mutS2; putative DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2 D SpyM51763 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL D SpyM50620 xseA; putative exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D SpyM50621 xseB; putative exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D SpyM50811 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D SpyM51644 polC; DNA polymerase III PolC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D SpyM50002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D SpyM50713 putative DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D SpyM51527 holB; putative DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D SpyM50268 putative exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SpyM50748 dnaH; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D SpyM50296 ssb; single strand binding protein (SSB) K03111 ssb; single-strand DNA-binding protein D SpyM50099 putative single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D SpyM50284 hypothetical protein K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D SpyM51758 recA; RecA recombinase (recombinase A) K03553 recA; recombination protein RecA D SpyM51761 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA D SpyM50035 ruvB; Holliday junction DNA helicase, subunit B K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D SpyM50489 putative phage endodeoxyribonuclease K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10] D SpyM50452 priA; putative primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D SpyM50179 sms; putative DNA repair protein K04485 radA; DNA repair protein RadA/Sms D SpyM51828 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF D SpyM50326 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D SpyM50017 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) D SpyM50701 recR; recombination protein RecR K06187 recR; recombination protein RecR D SpyM50625 recN; putative DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N) D SpyM50437 recU; putative recombination protein U K03700 recU; recombination protein U D SpyM51212 addA; putative ATP-dependent exonuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-] D SpyM51213 addB; putative ATP-dependent exonuclease subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-] D SpyM51459 conserved hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase D SpyM50916 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D SpyM51251 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D SpyM50905 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D SpyM50630 hlpA; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta D SpyM51307 putative phage RecT family protein K07455 recT; recombination protein RecT D SpyM50282 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D SpyM50884 putative phage repressor-like protein K01356 lexA; repressor LexA [EC:3.4.21.88] D SpyM50470 RecX family protein K03565 recX; regulatory protein D SpyM51328 putative ATP-dependent DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D SpyM50737 putative ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D SpyM51512 nrdE; ribonucleoside-diphosphate reductase alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D SpyM51514 nrdF; ribonucleoside-diphosphate reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D SpyM50735 putative ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D SpyM51257 conserved hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] C 03029 Mitochondrial biogenesis [BR:spf03029] D SpyM50382 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2 D SpyM51188 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D SpyM51740 tsf; elongation factor Ts K02357 tsf; elongation factor Ts D SpyM51355 tufA; elongation factor Tu (EF-Tu) K02358 tuf; elongation factor Tu D SpyM50211 fus; elongation factor G (EF-G) K02355 fusA; elongation factor G D SpyM51478 era; GTP-binding protein Era homolog K03595 era; GTPase D SpyM50079 tyrS; putative tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D SpyM50141 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D SpyM51788 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D SpyM51783 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D SpyM50338 gatA; glutamyl-tRNA amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D SpyM50339 gatB; glutamyl-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D SpyM50337 gatC; glutamyl-tRNA amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D SpyM50296 ssb; single strand binding protein (SSB) K03111 ssb; single-strand DNA-binding protein D SpyM50099 putative single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D SpyM50347 dnaK; chaperone protein DnaK (heat shock protein 70) K04043 dnaK; molecular chaperone DnaK D SpyM50346 grpE; GrpE protein (HSP-70 cofactor) K03687 GRPE; molecular chaperone GrpE D SpyM51721 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D SpyM51722 groES; 10 kDa chaperonin K04078 groES; chaperonin GroES D SpyM50348 dnaJ; chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ D SpyM51177 putative cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D SpyM50944 putative cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D SpyM51561 membrane protein OxaA 2 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase D SpyM50188 membrane protein OxaA 1 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:spf02000] D SpyM50175 ABC transporter ATP-binding membrane protein K18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump D SpyM50176 ABC transporter ATP-binding membrane protein K18892 patB; ATP-binding cassette, subfamily B, multidrug efflux pump D SpyM50920 ABC transporter ATP-binding membrane protein K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump D SpyM50919 ABC transporter ATP-binding membrane protein K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump D SpyM50321 ABC transporter ATP-binding membrane protein K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial D SpyM50322 ABC transporter ATP-binding membrane protein K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial D SpyM51133 ABC transporter ATP-binding protein K15738 uup; ABC transport system ATP-binding/permease protein D SpyM50980 extracellular solute-binding protein K02012 afuA; iron(III) transport system substrate-binding protein D SpyM50959 potD; spermidine/putrescine extracellular binding protein K11069 potD; spermidine/putrescine transport system substrate-binding protein D SpyM50960 potC; spermidine/putrescine ABC transporter permease protein K11070 potC; spermidine/putrescine transport system permease protein D SpyM50961 potB; putative spermidine/putrescine ABC transporter permease protein K11071 potB; spermidine/putrescine transport system permease protein D SpyM50962 potA; putative spermidine/putrescine ABC transporter ATP-binding protein K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11] D SpyM50151 putative glycine-betaine binding permease protein K02001 proW; glycine betaine/proline transport system permease protein D SpyM50150 putative glycine betaine transport ATP-binding protein K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9] D SpyM50934 ABC-type glycine betaine transport system protein K05845 opuC; osmoprotectant transport system substrate-binding protein D SpyM50935 ABC-type glycine betaine transport system ATP-binding protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9] D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D SpyM50802 malX; putative maltose/maltodextrin-binding protein precursor K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein D SpyM50801 malC; putative maltose/maltodextrin ABC transport system permease protein K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D SpyM50800 malD; putative maltose/maltodextrin ABC transport system permease protein K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D SpyM50547 extracellular solute-binding protein K17318 lplA; putative aldouronate transport system substrate-binding protein D SpyM50545 binding-protein-dependent transport system membrane protein K17319 lplB; putative aldouronate transport system permease protein D SpyM50546 binding-protein-dependent transport system membrane protein K17320 lplC; putative aldouronate transport system permease protein D SpyM50132 basic lipoprotein K07335 bmpA; basic membrane protein A and related proteins D SpyM50856 putative lipoprotein K07335 bmpA; basic membrane protein A and related proteins D SpyM50858 ABC transporter permease protein K23535 nupB; general nucleoside transport system permease protein D SpyM50859 ABC transporter permease protein K23536 nupC; general nucleoside transport system permease protein D SpyM50857 ABC transporter ATP-binding protein K23537 nupA; general nucleoside transport system ATP-binding protein D SpyM50192 extracellular solute-binding lipoprotein K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D SpyM50193 putative transport system permease K02025 ABC.MS.P; multiple sugar transport system permease protein D SpyM50194 putative transport system permease K02026 ABC.MS.P1; multiple sugar transport system permease protein D SpyM50843 pstS; putative phosphate ABC transporter,extracellular phosphate-binding lipoprotein K02040 pstS; phosphate transport system substrate-binding protein D SpyM50844 pstC; putative phosphate ABC transporter permease protein K02037 pstC; phosphate transport system permease protein D SpyM50845 putative phosphate ABC transporter permease protein K02038 pstA; phosphate transport system permease protein D SpyM50847 pstB1; phosphate import ATP-binding protein 1 K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D SpyM50846 pstB2; phosphate import ATP-binding protein 2 K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D SpyM50789 putative glutamine ABC transporter,glutamine-binding protein/permease protein K10036 glnH; glutamine transport system substrate-binding protein D SpyM50788 glnQ1; putative glutamine ABC transporter, ATP-binding protein 1 K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1] D SpyM51102 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D SpyM51585 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D SpyM51101 transport system membrane protein K10009 tcyB; L-cystine transport system permease protein D SpyM50428 ABC transporter permease protein K10009 tcyB; L-cystine transport system permease protein D SpyM50429 ABC transporter ATP-binding protein K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1] D SpyM51211 extracellular solute-binding protein K23059 artP; arginine/lysine/histidine transporter system substrate-binding protein D SpyM50614 putative amino acid ABC transporter permease protein K17077 artQ; arginine/lysine/histidine transport system permease protein D SpyM50615 glnQ3; putative glutamine transporter, ATP-binding protein 3 K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1] D SpyM51584 putative lipoprotein K02073 metQ; D-methionine transport system substrate-binding protein D SpyM51582 putative D-methionine transport system permease protein K02072 metI; D-methionine transport system permease protein D SpyM51583 putative D-methionine transport system ATP-binding protein K02071 metN; D-methionine transport system ATP-binding protein D SpyM51016 putative exported protein K01989 K01989; putative tryptophan/tyrosine transport system substrate-binding protein D SpyM51014 ABC transporter permease protein K05832 K05832; putative tryptophan/tyrosine transport system permease protein D SpyM51013 ABC transporter ATP-binding protein K05833 K05833; putative tryptophan/tyrosine transport system ATP-binding protein D SpyM50215 glutamine ABC transporter, glutamine-binding protein/permease protein K17073 lysX1; putative lysine transport system substrate-binding protein D SpyM50214 glnQ2; putative glutamine ABC transporter, ATP-binding protein 2 K17076 lysY; putative lysine transport system ATP-binding protein D SpyM50819 putative amino acid ABC transporter,extracellular amino acid-binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein D SpyM50817 putative amino acid ABC transporter permease protein K02029 ABC.PA.P; polar amino acid transport system permease protein D SpyM50818 putative amino acid ABC transporter ATP-binding protein K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1] D SpyM50227 putative extracellular oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein D SpyM50228 putative oligopeptide transporter permease protein K15581 oppB; oligopeptide transport system permease protein D SpyM50229 putative oligopeptide transporter permease protein K15582 oppC; oligopeptide transport system permease protein D SpyM50230 putative oligopeptide transporter ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein D SpyM50231 putative oligopeptide transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein D SpyM51673 dppA; dipeptide-binding extracellular protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D SpyM51674 dppB; dipeptide transport system permease protein DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein D SpyM51675 dppC; dipeptide transport system permease protein DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein D SpyM51676 dppD; dipeptide transport system ATP-binding protein DppD K02031 ddpD; peptide/nickel transport system ATP-binding protein D SpyM51677 dppE; dipeptide transport system ATP-binding protein DppF K02032 ddpF; peptide/nickel transport system ATP-binding protein D SpyM51535 fhuD; putative ferrichrome-binding protein precursor K25308 fhuD; ferric hydroxamate/heme transport system substrate-binding protein D SpyM51536 fhuB; ferrichrome transport permease K25288 fhuB; ferric hydroxamate/heme transport system permease protein D SpyM51537 fhuG; ferrichrome transport permease K25289 fhuG; ferric hydroxamate/heme transport system permease protein D SpyM51534 fhuC; ferrichrome transport ATP-binding protein K25290 fhuA; ferric hydroxamate/heme transport system ATP-binding protein [EC:7.2.2.16] D SpyM50318 putative transport system extracellular binding lipoprotein K25113 htsA; heme transport system substrate-binding protein D SpyM50319 putative iron/heme permease K25114 htsB; heme transport system permease protein D SpyM50320 ABC transporter ATP-binding protein K25115 htsC; heme transport system ATP-binding protein [EC:7.6.2.5] D SpyM50317 putative membrane protein K25119 shp; heme transport system cell surface heme-binding protein D SpyM50316 putative iron transport-associated protein K25120 shr; heme sequestration protein D SpyM51680 lmb; laminin binding protein K09815 znuA; zinc transport system substrate-binding protein D SpyM51261 adcA; zinc-binding protein AdcA precursor K09815 znuA; zinc transport system substrate-binding protein D SpyM50077 ABC transporter permease protein K09816 znuB; zinc transport system permease protein D SpyM50076 ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D SpyM51497 mtsA; metal ABC transporter substrate-binding lipoprotein precursor K11704 mtsA; iron/zinc/manganese/copper transport system substrate-binding protein D SpyM51495 mtsC; metal cation ABC transporter membrane protein K11705 mtsC; iron/zinc/manganese/copper transport system permease protein D SpyM51496 mtsB; metal cation ABC transporter ATP-binding protein K11706 mtsB; iron/zinc/manganese/copper transport system ATP-binding protein D SpyM50159 BioY family protein K03523 bioY; biotin transport system substrate-specific component D SpyM50323 putative membrane protein K16926 htsT; energy-coupling factor transport system substrate-specific component D SpyM51362 putative membrane protein K16927 cbrT; energy-coupling factor transport system substrate-specific component D SpyM51816 putative cobalt transport protein K16785 ecfT; energy-coupling factor transport system permease protein D SpyM50324 putative membrane protein K16785 ecfT; energy-coupling factor transport system permease protein D SpyM51818 ABC transporter ATP-binding protein K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D SpyM51817 ABC transporter ATP-binding protein K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D SpyM50325 ABC transporter ATP-binding protein K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D SpyM51239 sagI; ABC-2 type transporter protein K25142 lnrN; linearmycin/streptolysin S transport system permease protein D SpyM51240 sagH; ABC-2 type transporter protein K25143 lnrM; linearmycin/streptolysin S transport system permease protein D SpyM51241 sagG; ABC transporter ATP-binding protein K25144 lnrL; linearmycin/streptolysin S transport system ATP-binding protein D SpyM51161 putative permease K24948 yknZ; antimicrobial peptide resistance transport system permease protein D SpyM51689 putative permease protein K24948 yknZ; antimicrobial peptide resistance transport system permease protein D SpyM51690 ABC transporter ATP-binding protein K24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-] D SpyM51162 ABC transporter ATP-binding protein K24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-] D SpyM51331 ftsX; putative cell division protein K09811 ftsX; cell division transport system permease protein D SpyM51332 ftsE; putative cell division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein D SpyM51440 putative membrane protein K25154 evrC; viologen exporter family transport system permease protein D SpyM51441 putative membrane protein K25155 evrB; viologen exporter family transport system permease protein D SpyM51442 ABC transporter ATP-binding protein K25156 evrA; viologen exporter family transport system ATP-binding protein D SpyM50375 ABC transporter protein EcsB K25157 ecsB; ABC-2 type transport system permease protein D SpyM50374 ABC transporter ATP-binding protein K25158 ecsA; ABC-2 type transport system ATP-binding protein D SpyM50328 putative membrane protein K01992 ABC-2.P; ABC-2 type transport system permease protein D SpyM51201 putative polysaccharide export ABC transporter permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein D SpyM50418 putative membrane protein K01992 ABC-2.P; ABC-2 type transport system permease protein D SpyM50809 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D SpyM50417 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D SpyM51200 putative polysaccharide export system ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D SpyM50327 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D SpyM51603 salY; putative salivaricin A transporter permease protein K02004 ABC.CD.P; putative ABC transport system permease protein D SpyM51216 putative permease K02004 ABC.CD.P; putative ABC transport system permease protein D SpyM50833 ABC transporter permease protein K02004 ABC.CD.P; putative ABC transport system permease protein D SpyM51604 salX; putative salivaricin A transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D SpyM50832 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D SpyM51215 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D SpyM50220 sufC; putative ABC transporter, ATP-binding protein K09013 sufC; Fe-S cluster assembly ATP-binding protein D SpyM50041 multi antimicrobial extrusion (MATE) family transporter K26937 dinF; MATE family, multidrug efflux pump D SpyM50723 major facilitator superfamily protein K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter D SpyM51504 putative glycerol-3-phosphate transporter K02445 glpT; MFS transporter, OPA family, glycerol-3-phosphate transporter D SpyM51458 pmrA; multi-drug resistance efflux pump K08161 mdtG; MFS transporter, DHA1 family, multidrug resistance protein D SpyM51762 lmrP; putative transporter protein K08152 lmrP; MFS transporter, DHA1 family, multidrug resistance protein B D SpyM51387 major facilitator superfamily protein K18926 lmrB; MFS transporter, DHA2 family, lincomycin resistance protein D SpyM50740 pstI; phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] D SpyM50739 ptsH; histidine-containing phosphocarrier protein (HPr) K02784 ptsH; phosphocarrier protein HPr D SpyM51662 putative glucose-specific phosphotransferase system (PTS), IIABC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208] D SpyM50308 scrA; putative sucrose-specific phosphotransferase system (PTS), IIABC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D SpyM51385 beta-glucoside-specific phosphotransferase system (PTS), IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D SpyM51743 sugar phosphotransferase system (PTS), IIABC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D SpyM51146 fruA; putative fructose-specific phosphotransferase system (PTS), IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D SpyM51609 lacF; putative lactose-specific phosphotransferase system (PTS), IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D SpyM51608 lacE; putative lactose-specific phosphotransferase system (PTS), IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D SpyM50784 putative lactose/cellobiose-specific phosphotransferase system (PTS), IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D SpyM51709 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D SpyM50783 putative lactose/cellobiose-specific phosphotransferase system (PTS), IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D SpyM51708 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D SpyM51707 sugar phosphotransferase system (PTS), IIC component K02761 celB; cellobiose PTS system EIIC component D SpyM50786 sugar phosphotransferase system (PTS), IIC component K02761 celB; cellobiose PTS system EIIC component D SpyM50389 sugar phosphotransferase system (PTS), IIA component K20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204] D SpyM50390 sugar phosphotransferase system (PTS), IIB component K20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204] D SpyM50391 sugar phosphotransferase system (PTS),galactitol-specific family, IIC component K20114 gatC; galactose PTS system EIIC component D SpyM50366 manL; putative mannose-specific phosphotransferase system (PTS), IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D SpyM50986 sugar phosphotransferase system (PTS),mannose/fructose family, IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D SpyM50365 manM; putative mannose-specific phosphotransferase system (PTS), IIC component K02795 manY; mannose PTS system EIIC component D SpyM50984 sugar phosphotransferase system (PTS),mannose/fructose family, IIC component K02795 manY; mannose PTS system EIIC component D SpyM50364 manN; putative mannose-specific phosphotransferase system (PTS), IID component K02796 manZ; mannose PTS system EIID component D SpyM50983 sugar phosphotransferase system (PTS),mannose/fructose family, IID component K02796 manZ; mannose PTS system EIID component D SpyM50985 sugar phosphotransferase system (PTS),mannose/fructose family, IIB component K19507 gfrB; fructoselysine/glucoselysine PTS system EIIB component [EC:2.7.1.-] D SpyM51340 putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-] D SpyM51342 agaV; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-] D SpyM51343 agaW; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component D SpyM51344 agaD; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component D SpyM50144 sugar phosphotransferase system (PTS), IIA component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D SpyM51637 putative PTS multi-domain regulator K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D SpyM50143 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D SpyM51636 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D SpyM51635 putative sugar-specific permease K03475 ulaA; ascorbate PTS system EIIC component D SpyM50142 putative sugar-specific permease, SgaT/UlaA family K03475 ulaA; ascorbate PTS system EIIC component D SpyM51435 sugar phosphotransferase system (PTS), fructose family, IIA component K05881 dhaM; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaM [EC:2.7.1.121] D SpyM50411 glpF1; glycerol uptake facilitator protein 1 K02440 glpF; glycerol uptake facilitator D SpyM51434 glpF2; glycerol uptake facilitator protein 2 K02440 glpF; glycerol uptake facilitator D SpyM50277 gla; glycerol facilitator-aquaporin K02440 glpF; glycerol uptake facilitator D SpyM51088 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D SpyM50699 putative formate/nitrite transporter family protein K21993 fdhC; formate transporter D SpyM51209 mscL; large-conductance mechanosensitive channel K03282 mscL; large conductance mechanosensitive channel D SpyM50241 mechanosensitive ion channel protein K22044 ybiO; moderate conductance mechanosensitive channel D SpyM50299 CorA-like Mg2+ transporter protein K03284 corA; magnesium transporter D SpyM51541 putative transport protein K03699 tlyC; magnesium and cobalt exporter, CNNM family D SpyM51034 putative phage minor tail protein K21449 ata; trimeric autotransporter adhesin D SpyM51155 cation efflux family protein K16264 czcD; cobalt-zinc-cadmium efflux system protein D SpyM51829 putative sugar uptake protein K05340 glcU; glucose uptake protein D SpyM51580 sodium:dicarboxylate symporter family protein K07862 sstT; serine/threonine transporter D SpyM51578 cation transport protein K03498 trkH; trk/ktr system potassium uptake protein D SpyM51579 TrkA family transport protein K03499 trkA; trk/ktr system potassium uptake protein D SpyM51167 pyrP; uracil permease K02824 uraA; uracil permease D SpyM50931 pbuX; putative xanthine permease K16169 pbuX; xanthine permease D SpyM50368 putative permease K06901 pbuG; adenine/guanine/hypoxanthine permease D SpyM50952 voltage gated chloride channel family protein K03281 clcA; chloride channel protein, CIC family D SpyM50734 voltage gated chloride channel K03281 clcA; chloride channel protein, CIC family D SpyM51254 voltage gated chloride channel protein K03281 clcA; chloride channel protein, CIC family D SpyM50401 putative Na+/Pi-cotransporter protein K03324 yjbB; phosphate:Na+ symporter D SpyM50707 probable potassium transport system protein K03549 kup; KUP system potassium uptake protein D SpyM51545 putative membrane protein K23675 fmnP; riboflavin transporter D SpyM51364 putative membrane protein K16789 thiT; thiamine transporter D SpyM50698 putative membrane protein K16788 niaX; niacin transporter D SpyM51357 ftsW; putative cell division protein K03588 ftsW; cell division protein FtsW D SpyM50900 putative glutaconyl-CoA decarboxylase beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D SpyM50894 putative Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D SpyM50888 putative carboxylase subunit K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] D SpyM50903 putative carboxylase subunit K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] D SpyM50902 putative membrane protein K01573 oadG; oxaloacetate decarboxylase (Na+ extruding) subunit gamma D SpyM50901 putative glutaconyl-CoA decarboxylase gamma subunit K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma D SpyM50895 putative decarboxylase gamma chain K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma D SpyM50568 putative cytochrome c-type biogenesis protein K06196 ccdA; cytochrome c-type biogenesis protein D SpyM51691 putative exported protein K24950 yknX; membrane fusion protein, antimicrobial resistance system D SpyM51163 putative exported protein K24950 yknX; membrane fusion protein, antimicrobial resistance system D SpyM50779 nicotinamide mononucleotide transporter K03811 pnuC; nicotinamide mononucleotide transporter C 02044 Secretion system [BR:spf02044] D SpyM50606 putative membrane protein K02221 yggT; YggT family protein D SpyM50711 comEA; putative competence protein K02237 comEA; competence protein ComEA D SpyM50302 putative cytidine and deoxycytidylate deaminase K01493 comEB; dCMP deaminase [EC:3.5.4.12] D SpyM50712 comEC; putative competence protein K02238 comEC; competence protein ComEC D SpyM50464 comFA; putative late competence protein K02240 comFA; competence protein ComFA D SpyM50465 comFC; putative late competence protein K02242 comFC; competence protein ComFC D SpyM50084 putative competence protein K02243 comGA; competence protein ComGA D SpyM50085 putative competence protein K02244 comGB; competence protein ComGB D SpyM50086 comYC; putative competence protein K02245 comGC; competence protein ComGC D SpyM50087 putative competence protein K02246 comGD; competence protein ComGD D SpyM50089 putative membrane protein K02248 comGF; competence protein ComGF D SpyM50592 type IV leader peptidase family protein K02236 comC; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D SpyM50312 secA; putative preprotein SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D SpyM51713 putative preprotein translocase SecE subunit K03073 secE; preprotein translocase subunit SecE D SpyM51457 secG; putative protein-export membrane protein K03075 secG; preprotein translocase subunit SecG D SpyM50064 secY; preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY D SpyM50883 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D SpyM51388 ftsY; putative cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor D SpyM51649 putative preprotein translocase subunit K03210 yajC; preprotein translocase subunit YajC D SpyM51561 membrane protein OxaA 2 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase D SpyM50188 membrane protein OxaA 1 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase C 02042 Bacterial toxins [BR:spf02042] D SpyM51511 putative mono-ADP-ribosyltransferase K11044 spyA; C3 family ADP-ribosyltransferase [EC:2.4.2.-] D SpyM51087 C4-dicarboxylate transporter/malic acid transport protein K11041 eta; exfoliative toxin A/B D SpyM50136 slo; streptolysin O precursor (thiol-activated cytolysin) K11031 slo; thiol-activated cytolysin D SpyM51541 putative transport protein K03699 tlyC; magnesium and cobalt exporter, CNNM family D SpyM50820 cfa; CAMP factor K11045 cfa; cAMP factor D SpyM51247 Streptolysin S precursor K11046 sagA; streptolysin S associated protein D SpyM50910 haemolysin-III related membrane protein K11068 hlyIII; hemolysin III D SpyM51021 speH; streptococcal exotoxin H precursor K11040 se; staphylococcal enterotoxin D SpyM51672 smeZ; mitogenic exotoxin Z precursor K11040 se; staphylococcal enterotoxin D SpyM51264 speC; exotoxin C precursor K11040 se; staphylococcal enterotoxin D SpyM50680 phage hyaluronoglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] D SpyM50524 putative phage hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] D SpyM50541 beta-N-acetylglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] D SpyM51271 putative phage hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] C 02022 Two-component system [BR:spf02022] D SpyM51428 vicK; sensor histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] D SpyM51429 vicR; response regulator protein K07668 vicR; two-component system, OmpR family, response regulator VicR D SpyM50851 ciaH; sensor histidine kinase K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3] D SpyM50850 ciaR; response regulator protein K14983 ciaR; two-component system, OmpR family, response regulator CiaR D SpyM51572 csrS; sensor histidine kinase K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3] D SpyM51573 csrR; response regulator protein K18941 arlR; two-component system, OmpR family, response regulator ArlR D SpyM51687 sensor histidine kinase K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3] D SpyM51688 response regulator protein K18987 irr; two-component system, OmpR family, response regulator Irr D SpyM50458 sensor histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3] D SpyM50459 response regulator protein K11618 liaR; two-component system, NarL family, response regulator LiaR D SpyM51602 salK; sensor histidine kinase K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK D SpyM51601 salR; response regulator protein K14989 salR; two-component system, NarL family, secretion system response regulator SalR D SpyM50957 putative sensor kinase K02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3] D SpyM50958 response regulator protein K02475 K02475; two-component system, CitB family, response regulator D SpyM50537 putative sensor kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D SpyM50183 fasB; sensor histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D SpyM50186 fasA; response regulator protein K07707 agrA; two-component system, LytTR family, response regulator AgrA D SpyM50549 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D SpyM50572 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D SpyM50981 response regulator protein K07720 yesN; two-component system, response regulator YesN D SpyM50550 response regulator protein K07720 yesN; two-component system, response regulator YesN C 02035 Bacterial motility proteins [BR:spf02035] D SpyM51102 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D SpyM51585 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:spf04812] D SpyM50603 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D SpyM50602 ftsA; putative cell division protein K03590 ftsA; cell division protein FtsA D SpyM51838 putative chromosome partitioning protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein C 04147 Exosome [BR:spf04147] D SpyM51248 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D SpyM50212 plr; glyceraldehyde-3-phosphate dehydrogenase,plasmin receptor K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D SpyM50252 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D SpyM50813 pyk; putative pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D SpyM51494 putative cyclophilin type peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D SpyM51721 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D SpyM50347 dnaK; chaperone protein DnaK (heat shock protein 70) K04043 dnaK; molecular chaperone DnaK D SpyM50167 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D SpyM51830 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D SpyM51355 tufA; elongation factor Tu (EF-Tu) K02358 tuf; elongation factor Tu D SpyM50373 HIT-family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D SpyM50917 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D SpyM51431 hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SpyM50065 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D SpyM51079 apt; adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D SpyM50409 glpK; glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D SpyM50255 glnA; putative glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SpyM51354 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D SpyM50696 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] C 02048 Prokaryotic defense system [BR:spf02048] D SpyM51597 type I restriction-modification system R protein K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] D SpyM51598 type I restriction-modification system S protein K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D SpyM51599 type I restriction-modification system M protein K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D SpyM50091 conserved hypothetical protein K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] D SpyM50653 phage DNA methylase K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] D SpyM51290 putative phage HNH endonuclease K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] D SpyM50474 hypothetical phage protein K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] D SpyM51407 putative plasmid stabilization system antitoxin protein K07473 dinJ; DNA-damage-inducible protein J D SpyM51406 putative plasmid stabilization system protein K19092 parE1_3_4; toxin ParE1/3/4 D SpyM50603 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D SpyM51095 parC; topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D SpyM51097 parE; topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D SpyM51177 putative cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D SpyM50944 putative cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels [BR:spf04040] C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules [BR:spf04090] C 01504 Antimicrobial resistance genes [BR:spf01504] D SpyM50343 putative D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D SpyM50792 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D SpyM50793 dltB; putative activated D-alanine transport protein K03739 dltB; membrane protein involved in D-alanine export D SpyM50794 dltC; D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D SpyM50795 dltD; putative D-alanyl-lipoteichoic acid biosynthesis protein K03740 dltD; D-alanine transfer protein C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins [BR:spf00536] D SpyM50680 phage hyaluronoglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] D SpyM50524 putative phage hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] D SpyM50541 beta-N-acetylglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] D SpyM51271 putative phage hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:spf00537] D SpyM50680 phage hyaluronoglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] D SpyM50524 putative phage hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] D SpyM50541 beta-N-acetylglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] D SpyM51271 putative phage hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] D SpyM50134 nga; nicotine adenine dinucleotide glycohydrolase precursor K18153 nga; NAD+ glycohydrolase [EC:3.2.2.5] C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:spf03100] D tRNA-Ala-1 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala D tRNA-Ala-2 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala D tRNA-Ala-4 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala D tRNA-Ala-3 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala D tRNA-Ala-5 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala D tRNA-Ala-6 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala D tRNA-Arg-7 tRNA-Arg_(TCT); tRNA-Arg K14219 tRNA-Arg; tRNA Arg D tRNA-Arg-1 tRNA-Arg_(ACG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg D tRNA-Arg-3 tRNA-Arg_(ACG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg D tRNA-Arg-4 tRNA-Arg_(CCG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg D tRNA-Arg-5 tRNA-Arg_(CCT); tRNA-Arg K14219 tRNA-Arg; tRNA Arg D tRNA-Arg-6 tRNA-Arg_(ACG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg D tRNA-Arg-2 tRNA-Arg_(ACG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg D tRNA-Asn-1 tRNA-Asn_(GTT); tRNA-Asn K14220 tRNA-Asn; tRNA Asn D tRNA-Asn-2 tRNA-Asn_(GTT); tRNA-Asn K14220 tRNA-Asn; tRNA Asn D tRNA-Asn-3 tRNA-Asn_(GTT); tRNA-Asn K14220 tRNA-Asn; tRNA Asn D tRNA-Asp-2 tRNA-Asp_(GTC); tRNA-Asp K14221 tRNA-Asp; tRNA Asp D tRNA-Asp-3 tRNA-Asp_(GTC); tRNA-Asp K14221 tRNA-Asp; tRNA Asp D tRNA-Asp-1 tRNA-Asp_(GTC); tRNA-Asp K14221 tRNA-Asp; tRNA Asp D tRNA-Cys tRNA-Cys_(GCA); tRNA-Cys K14222 tRNA-Cys; tRNA Cys D tRNA-Gln-2 tRNA-Gln_(TTG); tRNA-Gln K14223 tRNA-Gln; tRNA Gln D tRNA-Gln-1 tRNA-Gln_(TTG); tRNA-Gln K14223 tRNA-Gln; tRNA Gln D tRNA-Glu-1 tRNA-Glu_(TTC); tRNA-Glu K14224 tRNA-Glu; tRNA Glu D tRNA-Glu-3 tRNA-Glu_(TTC); tRNA-Glu K14224 tRNA-Glu; tRNA Glu D tRNA-Glu-2 tRNA-Glu_(TTC); tRNA-Glu K14224 tRNA-Glu; tRNA Glu D tRNA-Gly-1 tRNA-Gly_(GCC); tRNA-Gly K14225 tRNA-Gly; tRNA Gly D tRNA-Gly-2 tRNA-Gly_(GCC); tRNA-Gly K14225 tRNA-Gly; tRNA Gly D tRNA-Gly-3 tRNA-Gly_(TCC); tRNA-Gly K14225 tRNA-Gly; tRNA Gly D tRNA-Gly-4 tRNA-Gly_(TCC); tRNA-Gly K14225 tRNA-Gly; tRNA Gly D tRNA-His tRNA-His_(GTG); tRNA-His K14226 tRNA-His; tRNA His D tRNA-Ile-2 tRNA-Ile_(GAT); tRNA-Ile K14227 tRNA-Ile; tRNA Ile D tRNA-Ile-3 tRNA-Ile_(GAT); tRNA-Ile K14227 tRNA-Ile; tRNA Ile D tRNA-Ile-1 tRNA-Ile_(GAT); tRNA-Ile K14227 tRNA-Ile; tRNA Ile D tRNA-Leu-1 tRNA-Leu_(TAG); tRNA-Leu K14228 tRNA-Leu; tRNA Leu D tRNA-Leu-5 tRNA-Leu_(CAA); tRNA-Leu K14228 tRNA-Leu; tRNA Leu D tRNA-Leu-2 tRNA-Leu_(TAA); tRNA-Leu K14228 tRNA-Leu; tRNA Leu D tRNA-Leu-3 tRNA-Leu_(TAG); tRNA-Leu K14228 tRNA-Leu; tRNA Leu D tRNA-Leu-7 tRNA-Leu_(TAG); tRNA-Leu K14228 tRNA-Leu; tRNA Leu D tRNA-Leu-4 tRNA-Leu_(TAA); tRNA-Leu K14228 tRNA-Leu; tRNA Leu D tRNA-Leu-6 tRNA-Leu_(AAG); tRNA-Leu K14228 tRNA-Leu; tRNA Leu D tRNA-Lys-1 tRNA-Lys_(TTT); tRNA-Lys K14229 tRNA-Lys; tRNA Lys D tRNA-Lys-2 tRNA-Lys_(TTT); tRNA-Lys K14229 tRNA-Lys; tRNA Lys D tRNA-Lys-3 tRNA-Lys_(TTT); tRNA-Lys K14229 tRNA-Lys; tRNA Lys D tRNA-Lys-4 tRNA-Lys_(CTT); tRNA-Lys K14229 tRNA-Lys; tRNA Lys D tRNA-Met-1 tRNA-Met_(CAT); tRNA-Met K14230 tRNA-Met; tRNA Met D tRNA-Met-2 tRNA-Met_(CAT); tRNA-Met K14230 tRNA-Met; tRNA Met D tRNA-Met-3 tRNA-Met_(CAT); tRNA-Met K14230 tRNA-Met; tRNA Met D tRNA-Phe-1 tRNA-Phe_(GAA); tRNA-Phe K14231 tRNA-Phe; tRNA Phe D tRNA-Phe-2 tRNA-Phe_(GAA); tRNA-Phe K14231 tRNA-Phe; tRNA Phe D tRNA-Pro-1 tRNA-Pro_(TGG); tRNA-Pro K14232 tRNA-Pro; tRNA Pro D tRNA-Pro-2 tRNA-Pro_(TGG); tRNA-Pro K14232 tRNA-Pro; tRNA Pro D tRNA-Ser-4 tRNA-Ser_(GGA); tRNA-Ser K14233 tRNA-Ser; tRNA Ser D tRNA-Ser-1 tRNA-Ser_(TGA); tRNA-Ser K14233 tRNA-Ser; tRNA Ser D tRNA-Ser-2 tRNA-Ser_(GCT); tRNA-Ser K14233 tRNA-Ser; tRNA Ser D tRNA-Ser-3 tRNA-Ser_(TGA); tRNA-Ser K14233 tRNA-Ser; tRNA Ser D tRNA-Thr-1 tRNA-Thr_(TGT); tRNA-Thr K14234 tRNA-Thr; tRNA Thr D tRNA-Thr-3 tRNA-Thr_(TGT); tRNA-Thr K14234 tRNA-Thr; tRNA Thr D tRNA-Thr-4 tRNA-Thr_(GGT); tRNA-Thr K14234 tRNA-Thr; tRNA Thr D tRNA-Thr-2 tRNA-Thr_(TGT); tRNA-Thr K14234 tRNA-Thr; tRNA Thr D tRNA-Trp tRNA-Trp_(CCA); tRNA-Trp K14235 tRNA-Trp; tRNA Trp D tRNA-Tyr-2 tRNA-Tyr_(GTA); tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D tRNA-Tyr-1 tRNA-Tyr_(GTA); tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D tRNA-Val-1 tRNA-Val_(TAC); tRNA-Val K14237 tRNA-Val; tRNA Val D tRNA-Val-3 tRNA-Val_(TAC); tRNA-Val K14237 tRNA-Val; tRNA Val D tRNA-Val-2 tRNA-Val_(TAC); tRNA-Val K14237 tRNA-Val; tRNA Val D tRNA-Val-4 tRNA-Val_(TAC); tRNA-Val K14237 tRNA-Val; tRNA Val D 16S_rRNA-1 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 16S_rRNA-3 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 16S_rRNA-6 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 16S_rRNA-2 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 16S_rRNA-4 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 16S_rRNA-5 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D 23S_rRNA-2 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 23S_rRNA-1 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 23S_rRNA-3 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 23S_rRNA-4 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 23S_rRNA-5 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 23S_rRNA-6 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D 5S_rRNA-1 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D 5S_rRNA-3 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D 5S_rRNA-2 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D 5S_rRNA-4 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D 5S_rRNA-5 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D 5S_rRNA-6 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D ssrA ssrA; tmRNA (RF00023) as predicted by Rfam, score 139.25 K15035 ssrA; transfer-messenger RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D SpyM51339 idnO; putative gluconate 5-dehydrogenase K00046 idnO; gluconate 5-dehydrogenase [EC:1.1.1.69] D SpyM51519 lctO; L-lactate oxidase K10530 lctO; L-lactate oxidase [EC:1.1.3.2] D SpyM51727 ndh; NADH dehydrogenase K03387 ahpF; NADH-dependent peroxiredoxin subunit F [EC:1.8.1.-] D SpyM51486 msrA; peptide methionine sulfoxide reductase K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] D SpyM50570 msrAB; peptide methionine sulfoxide reductase K12267 msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12] D SpyM50988 msrB; peptide methionine sulfoxide reductase K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] D SpyM51726 ahpC; alkyl hydroperoxide reductase subunit C K24119 ahpC; NADH-dependent peroxiredoxin subunit C [EC:1.11.1.26] D SpyM51151 pyridine nucleotide-disulphide oxidoreductase family protein K21567 fnr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] D SpyM51111 ArsC family protein K00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1] D SpyM51748 nrdG; putative anaerobic ribonucleoside-triphosphate reductase activating protein K04068 nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4] D SpyM51540 pflC; pyruvate formate-lyase activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D SpyM51712 putative pyruvate formate-lyase activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D SpyM50440 putative RNA methylase family protein K07444 ypsC; putative N6-adenine-specific DNA methylase [EC:2.1.1.-] D SpyM51454 putative glutamine cyclotransferase K22757 QCT; glutaminyl-peptide cyclotransferase [EC:2.3.2.5] D SpyM51417 glycosyltransferase K21349 ggs; glucosylglycerate synthase [EC:2.4.1.268] D SpyM51376 lgt; prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145] D SpyM50930 ApbE family protein K03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180] D SpyM50249 conserved hypothetical protein K07030 fakA; fatty acid kinase [EC:2.7.2.18] D SpyM51055 putative phage DNA polymerase K02334 dpo; DNA polymerase bacteriophage-type [EC:2.7.7.7] D SpyM50998 putative membrane protein K18672 dacA; diadenylate cyclase [EC:2.7.7.85] D SpyM51377 ptsK; HPr kinase/phosphorylase K06023 hprK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-] D SpyM51011 putative esterase K03930 estA; putative tributyrin esterase [EC:3.1.1.-] D SpyM51594 conserved hypothetical protein K07015 yqeG; putative phosphatase [EC:3.1.3.-] D SpyM51809 DHH family protein K22927 gdpP; cyclic-di-AMP phosphodiesterase [EC:3.1.4.59] D SpyM50199 TatD related DNase K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D SpyM50200 conserved hypothetical protein K05985 rnmV; ribonuclease M5 [EC:3.1.26.8] D SpyM51652 dexB; glucan 1,6-alpha-glucosidase K01215 dexB; glucan 1,6-alpha-glucosidase [EC:3.2.1.70] D SpyM51341 ugl; putative unsaturated glucuronyl hydrolase K18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180] D SpyM50225 putative D-alanyl-D-alanine carboxypeptidase K01286 E3.4.16.4; D-alanyl-D-alanine carboxypeptidase [EC:3.4.16.4] D SpyM51131 fms; peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D SpyM51641 def; polypeptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D SpyM50742 polysaccharide deacetylase family protein K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104] D SpyM50118 Endoribonuclease L-PSP family protein K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10] D SpyM51483 myosin-crossreactive antigen K10254 ohyA; oleate hydratase [EC:4.2.1.53] D SpyM51347 cation transporting ATPase K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10] D SpyM50693 putative cation-transporting ATPase K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21] C 99981 Carbohydrate metabolism C 99982 Energy metabolism D SpyM51190A putative ferredoxin K05337 fer; ferredoxin D SpyM50223 iscU; NifU-like protein K04488 iscU; nitrogen fixation protein NifU and related proteins C 99983 Lipid metabolism D SpyM51135 DegV family protein K25232 fakB; fatty acid kinase fatty acid binding subunit D SpyM50627 conserved hypothetical protein K25232 fakB; fatty acid kinase fatty acid binding subunit C 99984 Nucleotide metabolism D SpyM51513 nrdI; NrdI protein K03647 nrdI; protein involved in ribonucleotide reduction D SpyM51660 putative NrdI-like protein K03647 nrdI; protein involved in ribonucleotide reduction D SpyM51263 streptococcal phage DNAse K15051 endA; DNA-entry nuclease D SpyM51702 sdbII; streptococcal phage-like DNAse K15051 endA; DNA-entry nuclease D SpyM50534 streptococcal phage DNAse K15051 endA; DNA-entry nuclease D SpyM50691 streptococcal phage DNAse K15051 endA; DNA-entry nuclease C 99985 Amino acid metabolism D SpyM50914 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein K08234 yaeR; glyoxylase I family protein D SpyM50604 conserved hypothetical protein K06997 yggS; PLP dependent protein C 99986 Glycan metabolism C 99987 Cofactor metabolism C 99988 Secondary metabolism C 99999 Others B B 09192 Unclassified: genetic information processing C 99973 Transcription D SpyM51725 csp; cold shock protein K03704 cspA; cold shock protein D SpyM51316 putative phage antirepressor protein K07741 antB; anti-repressor protein D SpyM50476 putative phage antirepressor protein K07741 antB; anti-repressor protein D SpyM50839 spxA; regulatory protein Spx K16509 spxA; regulatory protein spx D SpyM51757 regulatory protein Spx K16509 spxA; regulatory protein spx D SpyM51380 putative transcription accessory protein K06959 tex; protein Tex C 99974 Translation D SpyM50461 putative S1 RNA binding domain protein K07570 GSP13; general stress protein 13 C 99975 Protein processing D SpyM50242 tig; trigger factor (prolyl isomerase) K03545 tig; trigger factor D SpyM51455 smpB; SsrA-binding protein K03664 smpB; SsrA-binding protein D SpyM50738 nrdH; glutaredoxin-like protein K06191 nrdH; glutaredoxin-like protein NrdH D SpyM50218 mecA; adapter protein MecA K16511 mecA1_2; adapter protein MecA 1/2 C 99976 Replication and repair D SpyM50948 radC; DNA repair protein RadC K03630 radC; DNA repair protein RadC D SpyM50205 RmuC family protein K09760 rmuC; DNA recombination protein RmuC D SpyM50708 conserved hypothetical protein K07461 K07461; putative endonuclease D SpyM50906 SMF family protein K04096 smf; DNA processing protein D SpyM51078 putative DNA replication protein DnaD K02086 dnaD; DNA replication protein D SpyM51311 putative phage DNA replication protein K02086 dnaD; DNA replication protein D SpyM50641 hypothetical phage protein K02086 dnaD; DNA replication protein D SpyM51049 putative phage terminase, small subunit K07474 xtmA; phage terminase small subunit D SpyM51048 putative phage terminase, large subunit K06909 xtmB; phage terminase large subunit D SpyM51669 putative ATPase K07478 ycaJ; putative ATPase D SpyM51054 putative phage DNA primase/helicase protein K06919 K06919; putative DNA primase/helicase D SpyM51774 putative phage replication protein K06919 K06919; putative DNA primase/helicase D SpyM50071 insertion sequence IS1239 putative transposase K07482 K07482; transposase, IS30 family D SpyM50164 insertion sequence IS1239 putative transposase K07482 K07482; transposase, IS30 family D SpyM50798 putative transposase K07482 K07482; transposase, IS30 family D SpyM50974 insertion sequence IS1239 putative transposase K07482 K07482; transposase, IS30 family D SpyM50617 insertion sequence IS1239 putative transposase K07482 K07482; transposase, IS30 family D SpyM50235 putative transposase K07483 K07483; transposase D SpyM50775 insertion sequence IS861 putative transposase K07483 K07483; transposase D SpyM50771 putative transposase K07483 K07483; transposase D SpyM50733 putative transposase for IS element K07483 K07483; transposase D SpyM51392 putative transposase K07483 K07483; transposase D SpyM51393 putative transposase K07497 K07497; putative transposase D SpyM50774 isertion sequence IS861 putative transposase K07497 K07497; putative transposase C 99979 Viral proteins C 99998 Others D SpyM50270 conserved hypothetical protein K09747 ebfC; nucleoid-associated protein EbfC B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D SpyM50432 amino acid permease K03293 TC.AAT; amino acid transporter, AAT family D SpyM50014 putative amino acid permease K03294 TC.APA; basic amino acid/polyamine antiporter, APA family D SpyM50897 putative Mg2+/citrate complex transporter K03300 TC.CITMHS; citrate-Mg2+:H+ or citrate-Ca2+:H+ symporter, CitMHS family D SpyM50822 sodium:alanine symporter family protein K03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family D SpyM51581 putative branched-chain amino acid transport system carrier protein K03311 TC.LIVCS; branched-chain amino acid:cation transporter, LIVCS family D SpyM50264 putative Na+ dependent nucleoside transporter K03317 TC.CNT; concentrative nucleoside transporter, CNT family C 99978 Cell growth D SpyM50441 putative membrane protein K20073 mapZ; mid-cell-anchored protein Z D SpyM50189 putative ssDNA-binding protein K06346 jag; spoIIIJ-associated protein D SpyM51322 putative phage integrase K06400 spoIVCA; site-specific DNA recombinase C 99993 Cell motility C 99995 Signaling proteins D SpyM50597 BipA family GTPase K06207 typA; GTP-binding protein D SpyM51482 PhoH-like protein K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins C 99992 Structural proteins D SpyM51363 glycosyl hydrolases family protein K07273 acm; lysozyme C 99994 Others D SpyM50848 phoU; putative phosphate transport system protein K02039 phoU; phosphate transport system protein D SpyM51522 CutC family protein K06201 cutC; copper homeostasis protein B B 09194 Poorly characterized C 99996 General function prediction only D SpyM51750 putative oxidoreductase K03810 mviM; virulence factor D SpyM50721 competence protein CoiA-like family protein K06198 coiA; competence protein CoiA D SpyM50098 putative tRNA-binding protein K06878 K06878; tRNA-binding protein D SpyM51367 haloacid dehalogenase-like hydrolase K07025 K07025; putative hydrolase of the HAD superfamily D SpyM50224 sufB; conserved hypothetical protein K09014 sufB; Fe-S cluster assembly protein SufB D SpyM50221 sufD; conserved hypothetical protein K09015 sufD; Fe-S cluster assembly protein SufD D SpyM50757 ribonuclease BN-like family protein K07058 K07058; membrane protein D SpyM51090 conserved hypothetical protein K07146 K07146; UPF0176 protein D SpyM51576 LemA family protein K03744 lemA; LemA protein D SpyM51803 putative membrane protein K01421 yhgE; putative membrane protein D SpyM51799 putative membrane protein K08974 K08974; putative membrane protein D SpyM51383 putative membrane protein K08986 ycgQ; putative membrane protein D SpyM50816 PhnA protein K06193 phnA; protein PhnA C 99997 Function unknown D SpyM51349 putative phosphohydrolase K06885 K06885; uncharacterized protein D SpyM50245 putative exported protein K06889 K06889; uncharacterized protein D SpyM51557 putative membrane protein K06890 K06890; uncharacterized protein D SpyM50153 putative CoA binding protein K06929 K06929; uncharacterized protein D SpyM51558 conserved hypothetical protein K06950 K06950; uncharacterized protein D SpyM51158 conserved hypothetical protein K06960 K06960; uncharacterized protein D SpyM51624 conserved hypothetical protein K06962 K06962; uncharacterized protein D SpyM51237 endonuclease/exonuclease/phosphatase family surface anchored protein K07004 K07004; uncharacterized protein D SpyM51156 conserved hypothetical protein K07006 K07006; uncharacterized protein D SpyM51150 putative membrane protein K07035 K07035; uncharacterized protein D SpyM51214 putative neutral zinc metallopeptidase K07054 K07054; uncharacterized protein D SpyM51382 putative permease K07089 K07089; uncharacterized protein D SpyM51553 putative phosphoesterase K07095 K07095; uncharacterized protein D SpyM50697 conserved hypothetical protein K07105 K07105; uncharacterized protein D SpyM51081 short chain dehydrogenase K07124 K07124; uncharacterized protein D SpyM51543 radical SAM superfamily protein K07139 K07139; uncharacterized protein D SpyM51547 conserved hypothetical protein K08998 K08998; uncharacterized protein D SpyM50539 conserved hypothetical protein K09704 K09704; uncharacterized protein D SpyM50882 putative DNA-binding protein K09787 K09787; uncharacterized protein D SpyM51487 conserved hypothetical protein K00243 K00243; uncharacterized protein D SpyM51747 conserved hypothetical protein K09861 K09861; uncharacterized protein D SpyM50781 conserved hypothetical protein K09963 K09963; uncharacterized protein D SpyM51556 putative exported protein K09976 K09976; uncharacterized protein D SpyM50679 hypothetical phage protein K01163 K01163; uncharacterized protein D SpyM51173 conserved hypothetical protein K07584 ysxB; uncharacterized protein D SpyM50469 conserved hypothetical protein K07586 ygaC; uncharacterized protein D SpyM50380 conserved hypothetical protein K07742 ylxR; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: May 22, 2024