+D GENES KO
#
KEGG Orthology (KO) - Streptococcus pyogenes Manfredo (serotype M5)
%
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A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:spf00010]
D SpyM50595 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D SpyM50167 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D SpyM50812 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D SpyM50246 fba; fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D SpyM51354 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D SpyM50212 plr; glyceraldehyde-3-phosphate dehydrogenase,plasmin receptor K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D SpyM50252 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D SpyM50696 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D SpyM51248 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D SpyM50813 pyk; putative pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D SpyM51008 pdhA; putative pyruvate dehydrogenase E1 component,alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D SpyM51007 pdhB; putative pyruvate dehydrogenase E1 component,beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D SpyM51006 pdhC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SpyM50917 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D SpyM50039 adhE; aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase] K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
D SpyM50040 adhP; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SpyM50618 putative phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D SpyM50860 pgmA; putative phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D SpyM50741 gapN; putative NADP-dependent glyceraldehyde-3-phosphate dehydrogenase K00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9]
D SpyM51384 bglA; 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]
D SpyM50780 putative beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]
D SpyM50542 putative beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]
C 00020 Citrate cycle (TCA cycle) [PATH:spf00020]
D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SpyM51008 pdhA; putative pyruvate dehydrogenase E1 component,alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D SpyM51007 pdhB; putative pyruvate dehydrogenase E1 component,beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D SpyM51006 pdhC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
C 00030 Pentose phosphate pathway [PATH:spf00030]
D SpyM50167 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D SpyM50203 rpe; putative ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D SpyM50415 tkt; putative transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D SpyM51634 putative transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D SpyM50414 probable transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D SpyM51113 rpiA; ribose 5-phosphate isomerase A K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D SpyM50265 deoC; deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]
D SpyM51112 deoB; phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7]
D SpyM50618 putative phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D SpyM50860 pgmA; putative phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D SpyM50016 prsA1; ribose-phosphate pyrophosphokinase 1 K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D SpyM50943 prsA2; putative ribose-phosphate pyrophosphokinase 2 K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D SpyM51336 kgdA; putative KHG/KDPG aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase] K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]
D SpyM50741 gapN; putative NADP-dependent glyceraldehyde-3-phosphate dehydrogenase K00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9]
D SpyM51337 PfkB family carbohydrate kinase K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45]
D SpyM50246 fba; fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D SpyM50812 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C 00040 Pentose and glucuronate interconversions [PATH:spf00040]
D SpyM51825 hasB; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SpyM51415 putative UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SpyM51826 hasC1; UTP--glucose-1-phosphate uridylyltransferase 1 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SpyM50172 hasC2; UTP--glucose-1-phosphate uridylyltransferase 2 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SpyM50145 putative hexulose-6-phosphate synthase K03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85]
D SpyM50146 putative hexulose-6-phosphate isomerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22]
D SpyM50147 L-ribulose 5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]
D SpyM50203 rpe; putative ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
C 00051 Fructose and mannose metabolism [PATH:spf00051]
D SpyM50310 scrK; fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D SpyM50311 pmi; mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
D SpyM50812 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D SpyM51147 fruK; putative 1-phosphofructokinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56]
D SpyM50246 fba; fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D SpyM51354 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D SpyM51146 fruA; putative fructose-specific phosphotransferase system (PTS), IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202]
D SpyM50986 sugar phosphotransferase system (PTS),mannose/fructose family, IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D SpyM50366 manL; putative mannose-specific phosphotransferase system (PTS), IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191]
D SpyM50365 manM; putative mannose-specific phosphotransferase system (PTS), IIC component K02795 manY; mannose PTS system EIIC component
D SpyM50984 sugar phosphotransferase system (PTS),mannose/fructose family, IIC component K02795 manY; mannose PTS system EIIC component
D SpyM50364 manN; putative mannose-specific phosphotransferase system (PTS), IID component K02796 manZ; mannose PTS system EIID component
D SpyM50983 sugar phosphotransferase system (PTS),mannose/fructose family, IID component K02796 manZ; mannose PTS system EIID component
C 00052 Galactose metabolism [PATH:spf00052]
D SpyM51826 hasC1; UTP--glucose-1-phosphate uridylyltransferase 1 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SpyM50172 hasC2; UTP--glucose-1-phosphate uridylyltransferase 2 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SpyM50618 putative phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D SpyM50860 pgmA; putative phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D SpyM50595 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D SpyM50551 glycosyl hydrolase family 2 protein K01190 lacZ; beta-galactosidase [EC:3.2.1.23]
D SpyM51611 lacC2; tagatose-6-phosphate kinase 2 K00917 lacC; tagatose 6-phosphate kinase [EC:2.7.1.144]
D SpyM50812 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D SpyM50395 lacD1; tagatose 1,6-diphosphate aldolase 1 K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40]
D SpyM51610 lacD2; tagatose 1,6-diphosphate aldolase 2 K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40]
D SpyM51612 lacB2; galactose-6-phosphate isomerase LacB subunit 2 K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26]
D SpyM51613 lacA2; galactose-6-phosphate isomerase LacA subunit 2 K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26]
D SpyM50392 lacA1; galactose-6-phosphate isomerase LacA subunit 1 K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26]
D SpyM50393 lacB1; galactose-6-phosphate isomerase LacB subunit 1 K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26]
D SpyM51607 lacG; 6-phospho-beta-galactosidase K01220 E3.2.1.85; 6-phospho-beta-galactosidase [EC:3.2.1.85]
D SpyM51609 lacF; putative lactose-specific phosphotransferase system (PTS), IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207]
D SpyM51608 lacE; putative lactose-specific phosphotransferase system (PTS), IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207]
D SpyM50307 scrB; putative sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26]
D SpyM51340 putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-]
D SpyM51342 agaV; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-]
D SpyM51343 agaW; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component
D SpyM51344 agaD; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component
D SpyM51259 agaS; putative tagatose-6-phosphate aldose/ketose isomerase K02082 agaS; D-galactosamine 6-phosphate deaminase/isomerase [EC:3.5.99.-]
C 00053 Ascorbate and aldarate metabolism [PATH:spf00053]
D SpyM51825 hasB; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SpyM51415 putative UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SpyM50144 sugar phosphotransferase system (PTS), IIA component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]
D SpyM51637 putative PTS multi-domain regulator K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]
D SpyM50143 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D SpyM51636 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D SpyM51635 putative sugar-specific permease K03475 ulaA; ascorbate PTS system EIIC component
D SpyM50142 putative sugar-specific permease, SgaT/UlaA family K03475 ulaA; ascorbate PTS system EIIC component
D SpyM50149 conserved hypothetical protein K03476 ulaG; L-ascorbate 6-phosphate lactonase [EC:3.1.1.-]
D SpyM50145 putative hexulose-6-phosphate synthase K03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85]
D SpyM50146 putative hexulose-6-phosphate isomerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22]
D SpyM50147 L-ribulose 5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]
C 00500 Starch and sucrose metabolism [PATH:spf00500]
D SpyM50308 scrA; putative sucrose-specific phosphotransferase system (PTS), IIABC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211]
D SpyM50307 scrB; putative sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26]
D SpyM51826 hasC1; UTP--glucose-1-phosphate uridylyltransferase 1 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SpyM50172 hasC2; UTP--glucose-1-phosphate uridylyltransferase 2 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SpyM50784 putative lactose/cellobiose-specific phosphotransferase system (PTS), IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D SpyM51709 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D SpyM50783 putative lactose/cellobiose-specific phosphotransferase system (PTS), IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]
D SpyM51708 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]
D SpyM51707 sugar phosphotransferase system (PTS), IIC component K02761 celB; cellobiose PTS system EIIC component
D SpyM50786 sugar phosphotransferase system (PTS), IIC component K02761 celB; cellobiose PTS system EIIC component
D SpyM51384 bglA; 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]
D SpyM50780 putative beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]
D SpyM50542 putative beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]
D SpyM50805 glgP; putative glycogen phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
D SpyM50804 malM; putative 4-alpha-glucanotransferase K00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25]
D SpyM51662 putative glucose-specific phosphotransferase system (PTS), IIABC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208]
D SpyM51661 endonuclease/exonuclease/phosphatase family protein K06896 mapP; maltose 6'-phosphate phosphatase [EC:3.1.3.90]
D SpyM51743 sugar phosphotransferase system (PTS), IIABC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201]
D SpyM51742 treA; putative trehalose-6-phosphate hydrolase K01226 treC; trehalose-6-phosphate hydrolase [EC:3.2.1.93]
D SpyM50618 putative phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D SpyM50860 pgmA; putative phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D SpyM50595 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D SpyM50167 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D SpyM50310 scrK; fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:spf00520]
D SpyM50402 putative N-acetylglucosamine-6-phosphate deacetylase K01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]
D SpyM50718 nagB; glucosamine-6-phosphate isomerase K02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6]
D SpyM50310 scrK; fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D SpyM50815 glmS; glucosamine--fructose-6-phosphate aminotransferase [isomerizing] K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D SpyM50996 putative phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D SpyM51503 gcaD; bifunctional GlmU protein [includes: UDP-N-acetylglucosamine pyrophosphorylase; glucosamine-1-phosphate N-acetyltransferase] K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
D SpyM51224 murA1; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D SpyM50752 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D SpyM50963 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D SpyM50191 putative N-acetylmannosamine-6-phosphate 2-epimerase K01788 nanE; N-acylglucosamine-6-phosphate 2-epimerase [EC:5.1.3.9]
D SpyM50196 nanH; putative N-acetylneuraminate lyase K01639 E4.1.3.3; N-acetylneuraminate lyase [EC:4.1.3.3]
D SpyM50595 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D SpyM50618 putative phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D SpyM50860 pgmA; putative phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D SpyM51826 hasC1; UTP--glucose-1-phosphate uridylyltransferase 1 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SpyM50172 hasC2; UTP--glucose-1-phosphate uridylyltransferase 2 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SpyM51825 hasB; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SpyM51415 putative UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SpyM50986 sugar phosphotransferase system (PTS),mannose/fructose family, IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D SpyM50366 manL; putative mannose-specific phosphotransferase system (PTS), IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191]
D SpyM50365 manM; putative mannose-specific phosphotransferase system (PTS), IIC component K02795 manY; mannose PTS system EIIC component
D SpyM50984 sugar phosphotransferase system (PTS),mannose/fructose family, IIC component K02795 manY; mannose PTS system EIIC component
D SpyM50364 manN; putative mannose-specific phosphotransferase system (PTS), IID component K02796 manZ; mannose PTS system EIID component
D SpyM50983 sugar phosphotransferase system (PTS),mannose/fructose family, IID component K02796 manZ; mannose PTS system EIID component
D SpyM50167 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D SpyM50311 pmi; mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
C 00620 Pyruvate metabolism [PATH:spf00620]
D SpyM51008 pdhA; putative pyruvate dehydrogenase E1 component,alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D SpyM51007 pdhB; putative pyruvate dehydrogenase E1 component,beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D SpyM51006 pdhC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SpyM50281 pfl; formate acetyltransferase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54]
D SpyM50039 adhE; aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase] K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
D SpyM50040 adhP; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SpyM50092 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D SpyM50938 pta; putative phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D SpyM50813 pyk; putative pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D SpyM50361 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D SpyM50357 fabE; biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D SpyM50359 accC; biotin carboxylase subunit of acetyl-CoA carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D SpyM50360 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D SpyM51560 putative acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D SpyM50917 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D SpyM51449 gloA; putative lactoylglutathione lyase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]
D SpyM51330 metallo-beta-lactamase superfamily protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D SpyM50955 NAD-dependent malic enzyme K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
D SpyM50888 putative carboxylase subunit K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]
D SpyM50903 putative carboxylase subunit K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]
D SpyM50900 putative glutaconyl-CoA decarboxylase beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
D SpyM50894 putative Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
D SpyM50902 putative membrane protein K01573 oadG; oxaloacetate decarboxylase (Na+ extruding) subunit gamma
D SpyM51358 ppc; putative phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:spf00630]
D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM50255 glnA; putative glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SpyM50923 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SpyM51596 putative glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D SpyM51336 kgdA; putative KHG/KDPG aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase] K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]
C 00640 Propanoate metabolism [PATH:spf00640]
D SpyM50092 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D SpyM50938 pta; putative phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SpyM50281 pfl; formate acetyltransferase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54]
D SpyM50361 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D SpyM50357 fabE; biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D SpyM50359 accC; biotin carboxylase subunit of acetyl-CoA carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D SpyM50360 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D SpyM50917 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D SpyM51704 gldA; glycerol dehydrogenase K00005 gldA; glycerol dehydrogenase [EC:1.1.1.6]
C 00650 Butanoate metabolism [PATH:spf00650]
D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM50115 atoD1; acetate CoA-transferase alpha subunit 1 K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
D SpyM50446 atoD2; acetate CoA-transferase alpha subunit 2 K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
D SpyM50116 atoA1; acetate CoA-transferase beta subunit 1 K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]
D SpyM50039 adhE; aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase] K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
D SpyM50900 putative glutaconyl-CoA decarboxylase beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
D SpyM50894 putative Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
D SpyM50901 putative glutaconyl-CoA decarboxylase gamma subunit K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
D SpyM50895 putative decarboxylase gamma chain K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
D SpyM50979 putative succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D SpyM50281 pfl; formate acetyltransferase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54]
D SpyM51121 mvaS; 3-hydroxy-3-methylglutaryl coenzyme A synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D SpyM50444 putative D-beta-hydroxybutyrate dehydrogenase K00019 BDH1; 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30]
D SpyM50954 putative zinc-binding alcohol dehydrogenase K18369 adh2; alcohol dehydrogenase [EC:1.1.1.-]
D SpyM51329 putative acetoin reductase K03366 butA; meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304]
C 00660 C5-Branched dibasic acid metabolism
C 00562 Inositol phosphate metabolism [PATH:spf00562]
D SpyM50841 putative myo-inositol-1(or 4)-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D SpyM51505 conserved hypothetical protein K22230 iolU; scyllo-inositol 2-dehydrogenase (NADP+) [EC:1.1.1.-]
D SpyM51354 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:spf00190]
D SpyM51229 atpA; ATP synthase alpha chain K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D SpyM51227 atpD; ATP synthase beta chain K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D SpyM51228 atpG; ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D SpyM51230 atpH; putative ATP synthase delta chain K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D SpyM51226 atpC; ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D SpyM51232 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D SpyM51231 atpF; ATP synthase B chain K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D SpyM51233 atpE; ATP synthase C chain K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D SpyM50126 ntpA; V-type sodium ATP synthase subunit A K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
D SpyM50127 ntpB; V-type sodium ATP synthase subunit B K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B
D SpyM50124 ntpC; V-type sodium ATP synthase subunit C K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C
D SpyM50128 ntpD; V-type sodium ATP synthase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D
D SpyM50123 ntpE; V-type sodium ATP synthase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E
D SpyM50125 V-type sodium ATP synthase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F
D SpyM50120 hypothetical protein K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H
D SpyM50121 ntpI; V-type sodium ATP synthase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I
D SpyM50122 ntpK; V-type sodium ATP synthase subunit K K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K
D SpyM51539 ppaC; manganese-dependent inorganic pyrophosphatase K15986 ppaC; manganese-dependent inorganic pyrophosphatase [EC:3.6.1.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation in photosynthetic organisms
C 00720 Carbon fixation pathways in prokaryotes
C 00680 Methane metabolism [PATH:spf00680]
D SpyM50923 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D SpyM51248 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D SpyM51358 ppc; putative phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D SpyM50246 fba; fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D SpyM50812 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D SpyM50092 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D SpyM50938 pta; putative phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D SpyM50696 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D SpyM51421 conserved hypothetical protein K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34]
C 00910 Nitrogen metabolism [PATH:spf00910]
D SpyM50255 glnA; putative glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SpyM50582 arcC; carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2]
D SpyM50180 putative carbonic anhydrase K01673 cynT; carbonic anhydrase [EC:4.2.1.1]
C 00920 Sulfur metabolism [PATH:spf00920]
D SpyM51257 conserved hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
D SpyM51631 cysE; serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D SpyM50462 cysM; putative cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:spf00061]
D SpyM50361 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D SpyM50357 fabE; biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D SpyM50359 accC; biotin carboxylase subunit of acetyl-CoA carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D SpyM50360 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D SpyM50019 putative acyl carrier protein K02078 acpP; acyl carrier protein
D SpyM50352 acpP; acyl carrier protein (ACP) K02078 acpP; acyl carrier protein
D SpyM50354 fabD; putative malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D SpyM50351 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D SpyM50356 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D SpyM51506 putative short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SpyM50355 fabG; 3-oxoacyl-[acyl-carrier protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SpyM50358 fabZ; (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D SpyM50353 fabK; enoyl-ACP reductase K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
D SpyM50349 enoyl-CoA hydratase/isomerase family protein K18474 fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14]
D SpyM51431 hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:spf00071]
D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM51431 hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SpyM50039 adhE; aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase] K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
D SpyM50040 adhP; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:spf00561]
D SpyM51596 putative glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D SpyM51437 dihydroxyacetone kinase family protein K05878 dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121]
D SpyM51436 dihydroxyacetone kinase family protein K05879 dhaL; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaL [EC:2.7.1.121]
D SpyM51435 sugar phosphotransferase system (PTS), fructose family, IIA component K05881 dhaM; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaM [EC:2.7.1.121]
D SpyM51704 gldA; glycerol dehydrogenase K00005 gldA; glycerol dehydrogenase [EC:1.1.1.6]
D SpyM50409 glpK; glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30]
D SpyM50018 plsX; fatty acid/phospholipid synthesis protein K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D SpyM51098 putative membrane protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D SpyM50710 putative acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D SpyM51234 conserved hypothetical protein K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
D SpyM51444 putative glycosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]
D SpyM51445 putative glycosyltransferase K13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208]
D SpyM51185 putative sulfatase K19005 ltaS; lipoteichoic acid synthase [EC:2.7.8.20]
C 00564 Glycerophospholipid metabolism [PATH:spf00564]
D SpyM50173 gpsA; glycerol-3-phosphate dehydrogenase [NAD(P)+] K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
D SpyM50410 glpO; alpha-glycerophosphate oxidase K00105 E1.1.3.21; alpha-glycerophosphate oxidase [EC:1.1.3.21]
D SpyM51098 putative membrane protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D SpyM50710 putative acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D SpyM51234 conserved hypothetical protein K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
D SpyM51160 putative glycerophosphodiester phosphodiesterase K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]
D SpyM51647 putative phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]
D SpyM51819 pgsA; putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
D SpyM50290 putative PAP2 superfamily protein K01096 pgpB; phosphatidylglycerophosphatase B [EC:3.1.3.27 3.6.1.75 3.1.3.4 3.6.1.27]
D SpyM50872 putative cardiolipin synthetase K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
D SpyM50551 glycosyl hydrolase family 2 protein K01190 lacZ; beta-galactosidase [EC:3.2.1.23]
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:spf00230]
D SpyM51502 putative ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D SpyM51112 deoB; phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7]
D SpyM50618 putative phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D SpyM50860 pgmA; putative phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D SpyM50016 prsA1; ribose-phosphate pyrophosphokinase 1 K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D SpyM50943 prsA2; putative ribose-phosphate pyrophosphokinase 2 K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D SpyM50023 purF; putative amidophosphoribosyltransferase precursor K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D SpyM50029 purD; phosphoribosylamine-glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D SpyM50025 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D SpyM50022 putative phosphoribosylformylglycinamidine synthase protein K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
D SpyM50024 purM; phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D SpyM50031 purK; putative phosphoribosylaminoimidazole carboxylase ATPase subunit K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
D SpyM50030 purE; putative phosphoribosylaminoimidazole carboxylase catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D SpyM50033 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D SpyM51079 apt; adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D SpyM51130 putative surface-anchored 5'-nucleotidase K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
D SpyM51110 punA; putative purine nucleoside phosphorylase K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]
D SpyM51109 deoD; putative purine nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]
D SpyM50012 hpt; hypoxanthine-guanine phosphoribosyltransferase K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
D SpyM51830 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D SpyM51554 HAM1 protein homolog K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D SpyM50932 xpt; putative xanthine phosphoribosyltransferase K03816 xpt; xanthine phosphoribosyltransferase [EC:2.4.2.22]
D SpyM50879 guaA; GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D SpyM50933 GMP reductase K00364 guaC; GMP reductase [EC:1.7.1.7]
D SpyM50450 gmk; guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8]
D SpyM50737 putative ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SpyM51512 nrdE; ribonucleoside-diphosphate reductase alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SpyM51514 nrdF; ribonucleoside-diphosphate reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D SpyM50735 putative ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D SpyM51752 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D SpyM51658 relA; GTP pyrophosphokinase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D SpyM50941 conserved hypothetical protein K07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5]
D SpyM51129 conserved hypothetical protein K07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5]
D SpyM50131 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D SpyM50065 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D SpyM50582 arcC; carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2]
C 00240 Pyrimidine metabolism [PATH:spf00240]
D SpyM51164 carB; carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D SpyM51165 carA; carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D SpyM51166 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D SpyM51099 pyrC; putative dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3]
D SpyM50695 pyrD; putative dihydroorotate dehydrogenase K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1]
D SpyM51104 pyrE; orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D SpyM51105 pyrF; orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D SpyM51489 pyrH; uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D SpyM50244 pyrG; putative CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D SpyM51189 cmk; cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D SpyM50744 udk; uridine kinase K00876 udk; uridine kinase [EC:2.7.1.48]
D SpyM51130 putative surface-anchored 5'-nucleotidase K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
D SpyM50263 udp; putative uridine phosphorylase K00757 udp; uridine phosphorylase [EC:2.4.2.3]
D SpyM51531 upp; uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
D SpyM51168 pyrR; PyrR bifunctional protein [includes: pyrimidine operon regulatory protein; uracil phosphoribosyltransferase] K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]
D SpyM50855 cdd; cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5]
D SpyM51752 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D SpyM50737 putative ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SpyM51512 nrdE; ribonucleoside-diphosphate reductase alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SpyM51514 nrdF; ribonucleoside-diphosphate reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D SpyM50735 putative ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D SpyM50302 putative cytidine and deoxycytidylate deaminase K01493 comEB; dCMP deaminase [EC:3.5.4.12]
D SpyM51528 tmk; thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D SpyM50178 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SpyM50928 tdk; putative thymidine kinase K00857 tdk; thymidine kinase [EC:2.7.1.21]
D SpyM51120 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
D SpyM50937 putative NADP-dependent L-serine/L-allo-threonine dehydrogenase K16066 ydfG; 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:spf00250]
D SpyM50329 asnB; putative L-asparaginase K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]
D SpyM50584 asnA; aspartate--ammonia ligase K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1]
D SpyM51327 aspC; aspartate aminotransferase K22457 E2.6.1.14; asparagine---oxo-acid transaminase [EC:2.6.1.14]
D SpyM50332 putative aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]
D SpyM50131 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D SpyM50033 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D SpyM51166 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D SpyM50979 putative succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D SpyM50255 glnA; putative glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SpyM51164 carB; carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D SpyM51165 carA; carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D SpyM50815 glmS; glucosamine--fructose-6-phosphate aminotransferase [isomerizing] K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D SpyM50023 purF; putative amidophosphoribosyltransferase precursor K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:spf00260]
D SpyM50923 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D SpyM51596 putative glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D SpyM50696 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D SpyM50937 putative NADP-dependent L-serine/L-allo-threonine dehydrogenase K16066 ydfG; 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-]
D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SpyM51814 sdhA; putative L-serine dehydratase, alpha chain K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]
D SpyM51813 sdhB; putative L-serine dehydratase, beta chain K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]
C 00270 Cysteine and methionine metabolism [PATH:spf00270]
D SpyM51631 cysE; serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D SpyM50462 cysM; putative cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D SpyM50140 putative cystathionine beta-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D SpyM51419 putative S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D SpyM50751 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D SpyM51500 mtnN; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9]
D SpyM50747 conserved hypothetical protein K08968 msrC; L-methionine (R)-S-oxide reductase [EC:1.8.4.14]
D SpyM50442 luxS; S-ribosylhomocysteinase K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]
D SpyM51094 putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D SpyM50917 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D SpyM51814 sdhA; putative L-serine dehydratase, alpha chain K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]
D SpyM51813 sdhB; putative L-serine dehydratase, beta chain K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]
C 00280 Valine, leucine and isoleucine degradation [PATH:spf00280]
D SpyM51094 putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM51121 mvaS; 3-hydroxy-3-methylglutaryl coenzyme A synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:spf00290]
D SpyM51094 putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D SpyM50332 putative aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]
C 00300 Lysine biosynthesis
D SpyM50703 murF; putative UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
C 00310 Lysine degradation [PATH:spf00310]
D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM50979 putative succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D SpyM50115 atoD1; acetate CoA-transferase alpha subunit 1 K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
D SpyM50446 atoD2; acetate CoA-transferase alpha subunit 2 K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
D SpyM50116 atoA1; acetate CoA-transferase beta subunit 1 K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]
C 00220 Arginine biosynthesis [PATH:spf00220]
D SpyM50579 arcB; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D SpyM50577 arcA; arginine deiminase K01478 arcA; arginine deiminase [EC:3.5.3.6]
D SpyM50255 glnA; putative glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SpyM50582 arcC; carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2]
D SpyM50332 putative aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]
C 00330 Arginine and proline metabolism [PATH:spf00330]
D SpyM51103 putative amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D SpyM51666 putative surface-anchored amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D SpyM50094 proC; putative pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]
D SpyM50421 proA; gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
C 00340 Histidine metabolism [PATH:spf00340]
D SpyM51735 hutH; histidine ammonia-lyase K01745 hutH; histidine ammonia-lyase [EC:4.3.1.3]
D SpyM51729 hutU; urocanate hydratase K01712 hutU; urocanate hydratase [EC:4.2.1.49]
D SpyM51728 hutI; imidazolonepropionase K01468 hutI; imidazolonepropionase [EC:3.5.2.7]
D SpyM51736 hutG; formiminoglutamase K01479 hutG; formiminoglutamase [EC:3.5.3.8]
D SpyM51730 putative glutamate formiminotransferase K00603 fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2]
C 00350 Tyrosine metabolism [PATH:spf00350]
D SpyM50039 adhE; aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase] K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
D SpyM50040 adhP; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SpyM50979 putative succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00360 Phenylalanine metabolism
D SpyM51103 putative amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D SpyM51666 putative surface-anchored amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
C 00380 Tryptophan metabolism [PATH:spf00380]
D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM51103 putative amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D SpyM51666 putative surface-anchored amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:spf00400]
D SpyM50558 DAHP synthetase I family protein K03856 AROA2; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D SpyM50557 aroB; 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4]
D SpyM51183 aroD; 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]
D SpyM51423 aroE.2; putative shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
D SpyM50759 aroK; putative shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D SpyM50758 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D SpyM51182 aroF; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D SpyM51668 trpG; anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D SpyM51255 chorismate mutase type II protein K04516 AROA1; chorismate mutase [EC:5.4.99.5]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism
C 00430 Taurine and hypotaurine metabolism [PATH:spf00430]
D SpyM50938 pta; putative phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D SpyM50092 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
C 00440 Phosphonate and phosphinate metabolism
C 00450 Selenocompound metabolism [PATH:spf00450]
D SpyM50140 putative cystathionine beta-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D SpyM50222 csdB; putative cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D SpyM50431 putative thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D SpyM51515 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism [PATH:spf00460]
D SpyM50329 asnB; putative L-asparaginase K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]
D SpyM50584 asnA; aspartate--ammonia ligase K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1]
D SpyM50923 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:spf00470]
D SpyM50314 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D SpyM50702 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D SpyM50792 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
D SpyM50794 dltC; D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
D SpyM51555 glr; glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3]
D SpyM50599 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
C 00480 Glutathione metabolism [PATH:spf00480]
D SpyM50849 pepN; putative lysyl-aminopeptidase K01256 pepN; aminopeptidase N [EC:3.4.11.2]
D SpyM51088 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SpyM51180 gor; glutathione reductase K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7]
D SpyM51360 putative glutathione peroxidase K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation [PATH:spf00511]
D SpyM50551 glycosyl hydrolase family 2 protein K01190 lacZ; beta-galactosidase [EC:3.2.1.23]
D SpyM50538 glycosyl hydrolases family protein K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis [PATH:spf00542]
D SpyM50219 rgpG; putative glycosyl transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]
C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:spf00541]
D SpyM51826 hasC1; UTP--glucose-1-phosphate uridylyltransferase 1 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SpyM50172 hasC2; UTP--glucose-1-phosphate uridylyltransferase 2 K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SpyM51825 hasB; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SpyM51415 putative UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SpyM51073 rmlA; glucose-1-phosphate thymidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D SpyM51071 rmlB; putative dTDP-glucose-4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D SpyM51072 rmlC; putative dTDP-4-keto-6-deoxyglucose-3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D SpyM50311 pmi; mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
D SpyM51503 gcaD; bifunctional GlmU protein [includes: UDP-N-acetylglucosamine pyrophosphorylase; glucosamine-1-phosphate N-acetyltransferase] K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
C 00550 Peptidoglycan biosynthesis [PATH:spf00550]
D SpyM51224 murA1; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D SpyM50752 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D SpyM50963 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D SpyM51565 murC; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D SpyM50599 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D SpyM50702 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D SpyM50703 murF; putative UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D SpyM51479 dgk; diacylglycerol kinase K00887 dgkA; undecaprenol kinase [EC:2.7.1.66]
D SpyM51648 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D SpyM50217 bacA; undecaprenol kinase (bacitracin resistance protein) K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D SpyM51544 PAP2 superfamily protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]
D SpyM50426 mraY; phospho-N-acetylmuramoyl-pentapeptide-transfera se K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D SpyM50600 murG; putative UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyr ophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D SpyM50436 pbp1A; putative penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D SpyM51715 pbp2A; penicillin-binding protein 2a K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4]
D SpyM50971 putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D SpyM50226 putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D SpyM50343 putative D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
D SpyM51533 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-dia minopimelate ligase K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7]
D SpyM50999 Mur ligase family protein K23393 murT; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13]
D SpyM51000 conserved hypothetical protein K07009 gatD; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13]
D SpyM50878 murM; putative peptidoglycan branched peptide synthesis protein MurM K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10]
D SpyM51352 murM; putative peptidoglycan pentaglycine interpeptide biosynthesis protein K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10]
D SpyM51353 murN; putative peptidoglycan branched peptide synthesis protein K12554 murN; alanine adding enzyme [EC:2.3.2.-]
D SpyM50080 pbp1B; putative penicillin-binding protein 1B K03693 pbp1b; penicillin-binding protein 1B
D SpyM50425 pbpX; putative penicillin binding protein 2x K12556 pbp2X; penicillin-binding protein 2X
C 00552 Teichoic acid biosynthesis [PATH:spf00552]
D SpyM50217 bacA; undecaprenol kinase (bacitracin resistance protein) K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D SpyM51544 PAP2 superfamily protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]
D SpyM50219 rgpG; putative glycosyl transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]
D SpyM50792 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
D SpyM50794 dltC; D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
D SpyM50793 dltB; putative activated D-alanine transport protein K03739 dltB; membrane protein involved in D-alanine export
D SpyM50795 dltD; putative D-alanyl-lipoteichoic acid biosynthesis protein K03740 dltD; D-alanine transfer protein
D SpyM50371 LytR family regulatory protein K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-]
D SpyM50760 cell envelope-related transcriptional attenuator domain protein K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-]
D SpyM51185 putative sulfatase K19005 ltaS; lipoteichoic acid synthase [EC:2.7.8.20]
D SpyM51444 putative glycosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis [PATH:spf00543]
D SpyM50219 rgpG; putative glycosyl transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]
D SpyM51631 cysE; serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:spf00730]
D SpyM51177 putative cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SpyM50944 putative cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SpyM51176 thiI; putative thiamine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D SpyM50202 engC; probable GTPase EngC K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]
D SpyM50204 thiN; putative thiamin pyrophosphokinase K00949 thiN; thiamine pyrophosphokinase [EC:2.7.6.2]
D SpyM50065 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:spf00740]
D SpyM50367 putative haloacid dehalogenase-like hydrolase K21064 ycsE; 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.104]
D SpyM50838 ribC; putative riboflavin biosynthesis protein K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]
D SpyM50953 putative class B acid phosphatase K03788 aphA; acid phosphatase (class B) [EC:3.1.3.2]
D SpyM51502 putative ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
C 00750 Vitamin B6 metabolism [PATH:spf00750]
D SpyM50875 conserved hypothetical protein K00868 pdxK; pyridoxine kinase [EC:2.7.1.35]
D SpyM50238 thiD; putative phosphomethylpyrimidine kinase K00868 pdxK; pyridoxine kinase [EC:2.7.1.35]
C 00760 Nicotinate and nicotinamide metabolism [PATH:spf00760]
D SpyM50773 nadC; putative nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D SpyM50433 nicotinate phosphoribosyltransferase (NAPRTase) family protein K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D SpyM51110 punA; putative purine nucleoside phosphorylase K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]
D SpyM51109 deoD; putative purine nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]
D SpyM51130 putative surface-anchored 5'-nucleotidase K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
D SpyM51591 putative nicotinate-nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]
D SpyM50434 nadE; NH(3)-dependent NAD(+) synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D SpyM50134 nga; nicotine adenine dinucleotide glycohydrolase precursor K18153 nga; NAD+ glycohydrolase [EC:3.2.2.5]
D SpyM50940 ppnK; putative inorganic polyphosphate/ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D SpyM50979 putative succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00770 Pantothenate and CoA biosynthesis [PATH:spf00770]
D SpyM51149 putative ketopantoate reductase K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
D SpyM50853 coaA; pantothenate kinase K00867 coaA; type I pantothenate kinase [EC:2.7.1.33]
D SpyM50863 dpfB; putative pantothenate metabolism flavoprotein K21977 coaB; phosphopantothenate---cysteine ligase (CTP) [EC:6.3.2.5]
D SpyM50862 coaC; putative phosphopantothenoylcysteine decarboxylase K01598 PPCDC; phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36]
D SpyM50586 coaD; phosphopantetheine adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D SpyM51460 coaE; dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]
D SpyM50313 acpS; holo-[acyl-carrier protein] synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]
D SpyM51094 putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
C 00780 Biotin metabolism [PATH:spf00780]
D SpyM50356 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D SpyM51506 putative short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SpyM50355 fabG; 3-oxoacyl-[acyl-carrier protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SpyM50358 fabZ; (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D SpyM50749 birA; BirA bifunctional protein [includes: biotin operon repressor; biotin--[acetyl-CoA-carboxylase] synthetase] K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism [PATH:spf00785]
D SpyM50864 conserved hypothetical protein K16869 lipL; octanoyl-[GcvH]:protein N-octanoyltransferase [EC:2.3.1.204]
D SpyM50870 lplA; putative lipoate-protein ligase A K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D SpyM51001 putative lipoate-protein ligase A K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SpyM51008 pdhA; putative pyruvate dehydrogenase E1 component,alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D SpyM51007 pdhB; putative pyruvate dehydrogenase E1 component,beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D SpyM51006 pdhC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
C 00790 Folate biosynthesis [PATH:spf00790]
D SpyM50967 folE; GTP cyclohydrolase I K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
D SpyM50965 folQ; dihydroneopterin aldolase K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]
D SpyM50964 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridi ne pyrophosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D SpyM50966 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D SpyM51119 dyr; dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D SpyM50968 folC1; putative folypolyglutamate synthase 1 K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
D SpyM51179 folC2; putative folypolyglutamate synthase 2 K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
D SpyM51667 putative chorismate binding enzyme K03342 pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38]
C 00670 One carbon pool by folate [PATH:spf00670]
D SpyM51119 dyr; dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D SpyM51732 fhs2; putative formate--tetrahydrofolate ligase 2 K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]
D SpyM50871 fhs1; formate--tetrahydrofolate ligase 1 K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]
D SpyM50619 folD; FolD bifunctional protein [includes: methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase] K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D SpyM51731 putative formiminotetrahydrofolate cyclodeaminase K01500 fchA; methenyltetrahydrofolate cyclohydrolase [EC:3.5.4.9]
D SpyM50923 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D SpyM50025 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D SpyM51730 putative glutamate formiminotransferase K00603 fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2]
D SpyM50453 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D SpyM51120 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:spf00900]
D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM51121 mvaS; 3-hydroxy-3-methylglutaryl coenzyme A synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D SpyM51122 mvaA; 3-hydroxy-3-methylglutaryl-coenzyme A reductase K00054 mvaA; hydroxymethylglutaryl-CoA reductase [EC:1.1.1.88]
D SpyM51126 mvaK1; mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36]
D SpyM51124 mvaK2; phosphomevalonate kinase K00938 E2.7.4.2; phosphomevalonate kinase [EC:2.7.4.2]
D SpyM51125 mvaD; mevalonate diphosphate decarboxylase K01597 MVD; diphosphomevalonate decarboxylase [EC:4.1.1.33]
D SpyM51123 fni; isopentenyl-diphosphate delta-isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D SpyM50622 fps; putative geranyltranstransferase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D SpyM51648 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation [PATH:spf00903]
D SpyM50796 putative membrane protein K14731 mlhB; epsilon-lactone hydrolase [EC:3.1.1.83]
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D SpyM50415 tkt; putative transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis [PATH:spf00523]
D SpyM51073 rmlA; glucose-1-phosphate thymidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D SpyM51071 rmlB; putative dTDP-glucose-4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D SpyM51072 rmlC; putative dTDP-4-keto-6-deoxyglucose-3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
D SpyM51071 rmlB; putative dTDP-glucose-4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis
D SpyM50421 proA; gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
C 00261 Monobactam biosynthesis
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:spf00521]
D SpyM50595 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D SpyM50618 putative phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D SpyM50860 pgmA; putative phosphomannomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D SpyM50841 putative myo-inositol-1(or 4)-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D SpyM51073 rmlA; glucose-1-phosphate thymidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D SpyM51071 rmlB; putative dTDP-glucose-4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D SpyM51072 rmlC; putative dTDP-4-keto-6-deoxyglucose-3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
D SpyM50595 glkA; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
C 00525 Acarbose and validamycin biosynthesis [PATH:spf00525]
D SpyM51073 rmlA; glucose-1-phosphate thymidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D SpyM51071 rmlB; putative dTDP-glucose-4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
C 00401 Novobiocin biosynthesis
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D SpyM51668 trpG; anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
D SpyM50354 fabD; putative malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D SpyM51506 putative short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SpyM50355 fabG; 3-oxoacyl-[acyl-carrier protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
D SpyM50019 putative acyl carrier protein K02078 acpP; acyl carrier protein
D SpyM50352 acpP; acyl carrier protein (ACP) K02078 acpP; acyl carrier protein
C 00999 Biosynthesis of various plant secondary metabolites [PATH:spf00999]
D SpyM51419 putative S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D SpyM50751 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D SpyM51423 aroE.2; putative shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation [PATH:spf00362]
D SpyM50929 putative 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
D SpyM50900 putative glutaconyl-CoA decarboxylase beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
D SpyM50894 putative Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
D SpyM50901 putative glutaconyl-CoA decarboxylase gamma subunit K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
D SpyM50895 putative decarboxylase gamma chain K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00627 Aminobenzoate degradation [PATH:spf00627]
D SpyM51103 putative amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D SpyM51666 putative surface-anchored amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D SpyM51560 putative acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D SpyM50115 atoD1; acetate CoA-transferase alpha subunit 1 K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
D SpyM50446 atoD2; acetate CoA-transferase alpha subunit 2 K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
D SpyM50116 atoA1; acetate CoA-transferase beta subunit 1 K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation [PATH:spf00625]
D SpyM50040 adhP; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SpyM50039 adhE; aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase] K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
D SpyM50929 putative 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
C 00633 Nitrotoluene degradation
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation [PATH:spf00643]
D SpyM51103 putative amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D SpyM51666 putative surface-anchored amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
D SpyM50796 putative membrane protein K14731 mlhB; epsilon-lactone hydrolase [EC:3.1.1.83]
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
D SpyM50929 putative 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
C 00626 Naphthalene degradation [PATH:spf00626]
D SpyM50040 adhP; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SpyM50039 adhE; aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase] K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:spf03020]
D SpyM50081 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D SpyM50082 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D SpyM50069 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D SpyM50451 rpoZ; DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D SpyM50243 rpoE; putative DNA-directed RNA polymerase, delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
C 03022 Basal transcription factors
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:spf03010]
D SpyM51092 putative 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D SpyM51739 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D SpyM50050 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D SpyM51805 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D SpyM50061 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D SpyM50295 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D SpyM50210 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D SpyM50058 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D SpyM51619 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D SpyM50043 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D SpyM50068 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D SpyM50209 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D SpyM50067 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D SpyM50057 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D SpyM50261 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D SpyM51638 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D SpyM51159 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D SpyM50053 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D SpyM50297 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D SpyM50048 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D SpyM50852 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D SpyM51210 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D SpyM51490 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D SpyM50047 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D SpyM50044 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D SpyM50045 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D SpyM50056 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D SpyM50059 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D SpyM50972 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D SpyM51808 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D SpyM50973 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D SpyM51491 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D SpyM51620 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D SpyM50054 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D SpyM50063 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D SpyM50051 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D SpyM50070 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D SpyM50060 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D SpyM51253 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D SpyM51186 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D SpyM51174 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D SpyM50049 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D SpyM50046 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D SpyM50055 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D SpyM51172 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D SpyM50247 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D SpyM50052 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D SpyM50062 rpmD; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D SpyM51258 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D SpyM51790 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D SpyM51714 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D SpyM51791 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D SpyM51458A rpmGB; 50S ribosomal protein L33 2 K02913 RP-L33; large subunit ribosomal protein L33
D SpyM50190 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D SpyM51187 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D SpyM50066A rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D 16S_rRNA-1 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 16S_rRNA-3 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 16S_rRNA-6 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 16S_rRNA-2 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 16S_rRNA-4 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 16S_rRNA-5 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 23S_rRNA-2 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 23S_rRNA-1 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 23S_rRNA-3 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 23S_rRNA-4 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 23S_rRNA-5 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 23S_rRNA-6 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 5S_rRNA-1 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D 5S_rRNA-3 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D 5S_rRNA-2 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D 5S_rRNA-4 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D 5S_rRNA-5 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D 5S_rRNA-6 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:spf00970]
D tRNA-Ala-1 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D tRNA-Ala-2 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D tRNA-Ala-4 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D tRNA-Ala-3 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D tRNA-Ala-5 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D tRNA-Ala-6 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D tRNA-Arg-7 tRNA-Arg_(TCT); tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D tRNA-Arg-1 tRNA-Arg_(ACG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D tRNA-Arg-3 tRNA-Arg_(ACG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D tRNA-Arg-4 tRNA-Arg_(CCG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D tRNA-Arg-5 tRNA-Arg_(CCT); tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D tRNA-Arg-6 tRNA-Arg_(ACG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D tRNA-Arg-2 tRNA-Arg_(ACG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D tRNA-Asn-1 tRNA-Asn_(GTT); tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D tRNA-Asn-2 tRNA-Asn_(GTT); tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D tRNA-Asn-3 tRNA-Asn_(GTT); tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D tRNA-Asp-2 tRNA-Asp_(GTC); tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D tRNA-Asp-3 tRNA-Asp_(GTC); tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D tRNA-Asp-1 tRNA-Asp_(GTC); tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D tRNA-Cys tRNA-Cys_(GCA); tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D tRNA-Gln-2 tRNA-Gln_(TTG); tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D tRNA-Gln-1 tRNA-Gln_(TTG); tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D tRNA-Glu-1 tRNA-Glu_(TTC); tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D tRNA-Glu-3 tRNA-Glu_(TTC); tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D tRNA-Glu-2 tRNA-Glu_(TTC); tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D tRNA-Gly-1 tRNA-Gly_(GCC); tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D tRNA-Gly-2 tRNA-Gly_(GCC); tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D tRNA-Gly-3 tRNA-Gly_(TCC); tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D tRNA-Gly-4 tRNA-Gly_(TCC); tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D tRNA-His tRNA-His_(GTG); tRNA-His K14226 tRNA-His; tRNA His
D tRNA-Ile-2 tRNA-Ile_(GAT); tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D tRNA-Ile-3 tRNA-Ile_(GAT); tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D tRNA-Ile-1 tRNA-Ile_(GAT); tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D tRNA-Leu-1 tRNA-Leu_(TAG); tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D tRNA-Leu-5 tRNA-Leu_(CAA); tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D tRNA-Leu-2 tRNA-Leu_(TAA); tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D tRNA-Leu-3 tRNA-Leu_(TAG); tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D tRNA-Leu-7 tRNA-Leu_(TAG); tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D tRNA-Leu-4 tRNA-Leu_(TAA); tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D tRNA-Leu-6 tRNA-Leu_(AAG); tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D tRNA-Lys-1 tRNA-Lys_(TTT); tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D tRNA-Lys-2 tRNA-Lys_(TTT); tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D tRNA-Lys-3 tRNA-Lys_(TTT); tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D tRNA-Lys-4 tRNA-Lys_(CTT); tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D tRNA-Met-1 tRNA-Met_(CAT); tRNA-Met K14230 tRNA-Met; tRNA Met
D tRNA-Met-2 tRNA-Met_(CAT); tRNA-Met K14230 tRNA-Met; tRNA Met
D tRNA-Met-3 tRNA-Met_(CAT); tRNA-Met K14230 tRNA-Met; tRNA Met
D tRNA-Phe-1 tRNA-Phe_(GAA); tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D tRNA-Phe-2 tRNA-Phe_(GAA); tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D tRNA-Pro-1 tRNA-Pro_(TGG); tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D tRNA-Pro-2 tRNA-Pro_(TGG); tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D tRNA-Ser-4 tRNA-Ser_(GGA); tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D tRNA-Ser-1 tRNA-Ser_(TGA); tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D tRNA-Ser-2 tRNA-Ser_(GCT); tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D tRNA-Ser-3 tRNA-Ser_(TGA); tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D tRNA-Thr-1 tRNA-Thr_(TGT); tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D tRNA-Thr-3 tRNA-Thr_(TGT); tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D tRNA-Thr-4 tRNA-Thr_(GGT); tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D tRNA-Thr-2 tRNA-Thr_(TGT); tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D tRNA-Trp tRNA-Trp_(CCA); tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D tRNA-Tyr-2 tRNA-Tyr_(GTA); tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D tRNA-Tyr-1 tRNA-Tyr_(GTA); tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D tRNA-Val-1 tRNA-Val_(TAC); tRNA-Val K14237 tRNA-Val; tRNA Val
D tRNA-Val-3 tRNA-Val_(TAC); tRNA-Val K14237 tRNA-Val; tRNA Val
D tRNA-Val-2 tRNA-Val_(TAC); tRNA-Val K14237 tRNA-Val; tRNA Val
D tRNA-Val-4 tRNA-Val_(TAC); tRNA-Val K14237 tRNA-Val; tRNA Val
D SpyM50182 gltX; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
D SpyM50338 gatA; glutamyl-tRNA amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D SpyM50339 gatB; glutamyl-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D SpyM50337 gatC; glutamyl-tRNA amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D SpyM50726 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D SpyM51788 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D SpyM51326 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D SpyM50405 glyQ; glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D SpyM50406 glyS; glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D SpyM51443 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D SpyM50362 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D SpyM51628 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D SpyM51515 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D SpyM50453 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D SpyM50564 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D SpyM50141 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D SpyM50609 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D SpyM51368 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D SpyM51783 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D SpyM51645 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D SpyM51789 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D SpyM51220 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D SpyM51219 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D SpyM50079 tyrS; putative tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D SpyM51831 trsA; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:spf03060]
D SpyM50064 secY; preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY
D SpyM51713 putative preprotein translocase SecE subunit K03073 secE; preprotein translocase subunit SecE
D SpyM51457 secG; putative protein-export membrane protein K03075 secG; preprotein translocase subunit SecG
D SpyM51649 putative preprotein translocase subunit K03210 yajC; preprotein translocase subunit YajC
D SpyM51561 membrane protein OxaA 2 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
D SpyM50188 membrane protein OxaA 1 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
D SpyM50312 secA; putative preprotein SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D SpyM50883 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D SpyM51388 ftsY; putative cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor
D SpyM50285 spi; putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D SpyM50814 sipC; putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D SpyM50105 putative signal peptidase K03100 lepB; signal peptidase I [EC:3.4.21.89]
D SpyM51170 lspA; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:spf04122]
D SpyM51177 putative cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SpyM50944 putative cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SpyM51812 putative tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D SpyM51176 thiI; putative thiamine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
C 03050 Proteasome
C 03018 RNA degradation [PATH:spf03018]
D SpyM51248 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D SpyM51633 pnpA; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D SpyM51456 rnr; putative exoribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D SpyM50706 DEAD box helicase family protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D SpyM50449 putative phosphohydrolase K18682 rny; ribonucrease Y [EC:3.1.-.-]
D SpyM50256 metallo-beta-lactamase superfamily protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D SpyM51012 metallo-beta-lactamase superfamily protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D SpyM50812 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D SpyM50347 dnaK; chaperone protein DnaK (heat shock protein 70) K04043 dnaK; molecular chaperone DnaK
D SpyM51721 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:spf03030]
D SpyM50268 putative exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D SpyM50811 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D SpyM51644 polC; DNA polymerase III PolC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
D SpyM50748 dnaH; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D SpyM51527 holB; putative DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D SpyM50713 putative DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D SpyM50002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D SpyM51807 dnaC; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D SpyM51208 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D SpyM50296 ssb; single strand binding protein (SSB) K03111 ssb; single-strand DNA-binding protein
D SpyM50099 putative single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SpyM50907 rnh; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D SpyM50286 ribonuclease HIII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4]
D SpyM50152 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D SpyM51235 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03410 Base excision repair [PATH:spf03410]
D SpyM51077 nth; putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D SpyM51100 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
D SpyM50293 putative A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D SpyM51461 fpg; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D SpyM51760 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
D SpyM51520 exoA; exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D SpyM50152 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D SpyM51080 putative single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D SpyM51235 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03420 Nucleotide excision repair [PATH:spf03420]
D SpyM50006 trcF; putative transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D SpyM50300 uvrA; UvrABC system protein A (UvrA protein) K03701 uvrA; excinuclease ABC subunit A
D SpyM50790 uvrB; UvrABC system protein B (UvrB protein) K03702 uvrB; excinuclease ABC subunit B
D SpyM50978 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
D SpyM50823 pcrA; putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D SpyM50152 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D SpyM51235 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03430 Mismatch repair [PATH:spf03430]
D SpyM51780 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D SpyM50289 mutS2; putative DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2
D SpyM51763 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D SpyM50823 pcrA; putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D SpyM50620 xseA; putative exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D SpyM50621 xseB; putative exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D SpyM51080 putative single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D SpyM50296 ssb; single strand binding protein (SSB) K03111 ssb; single-strand DNA-binding protein
D SpyM50099 putative single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SpyM50811 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D SpyM51644 polC; DNA polymerase III PolC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
D SpyM50002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D SpyM50748 dnaH; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D SpyM50713 putative DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D SpyM51527 holB; putative DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D SpyM50268 putative exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D SpyM51235 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03440 Homologous recombination [PATH:spf03440]
D SpyM51080 putative single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D SpyM50296 ssb; single strand binding protein (SSB) K03111 ssb; single-strand DNA-binding protein
D SpyM50099 putative single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SpyM51828 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
D SpyM50017 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
D SpyM50701 recR; recombination protein RecR K06187 recR; recombination protein RecR
D SpyM51758 recA; RecA recombinase (recombinase A) K03553 recA; recombination protein RecA
D SpyM50152 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D SpyM51761 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D SpyM50035 ruvB; Holliday junction DNA helicase, subunit B K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D SpyM50326 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D SpyM50284 hypothetical protein K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
D SpyM50811 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D SpyM51644 polC; DNA polymerase III PolC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
D SpyM50002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D SpyM50748 dnaH; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D SpyM50713 putative DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D SpyM51527 holB; putative DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D SpyM50268 putative exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D SpyM50452 priA; putative primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
C 03450 Non-homologous end-joining
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1 [PATH:spf03250]
D SpyM51494 putative cyclophilin type peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus and Lyssavirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:spf02010]
D SpyM50980 extracellular solute-binding protein K02012 afuA; iron(III) transport system substrate-binding protein
D SpyM50959 potD; spermidine/putrescine extracellular binding protein K11069 potD; spermidine/putrescine transport system substrate-binding protein
D SpyM50960 potC; spermidine/putrescine ABC transporter permease protein K11070 potC; spermidine/putrescine transport system permease protein
D SpyM50961 potB; putative spermidine/putrescine ABC transporter permease protein K11071 potB; spermidine/putrescine transport system permease protein
D SpyM50962 potA; putative spermidine/putrescine ABC transporter ATP-binding protein K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11]
D SpyM50151 putative glycine-betaine binding permease protein K02001 proW; glycine betaine/proline transport system permease protein
D SpyM50150 putative glycine betaine transport ATP-binding protein K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9]
D SpyM50934 ABC-type glycine betaine transport system protein K05845 opuC; osmoprotectant transport system substrate-binding protein
D SpyM50935 ABC-type glycine betaine transport system ATP-binding protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D SpyM50802 malX; putative maltose/maltodextrin-binding protein precursor K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein
D SpyM50801 malC; putative maltose/maltodextrin ABC transport system permease protein K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D SpyM50800 malD; putative maltose/maltodextrin ABC transport system permease protein K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D SpyM50547 extracellular solute-binding protein K17318 lplA; putative aldouronate transport system substrate-binding protein
D SpyM50545 binding-protein-dependent transport system membrane protein K17319 lplB; putative aldouronate transport system permease protein
D SpyM50546 binding-protein-dependent transport system membrane protein K17320 lplC; putative aldouronate transport system permease protein
D SpyM50132 basic lipoprotein K07335 bmpA; basic membrane protein A and related proteins
D SpyM50856 putative lipoprotein K07335 bmpA; basic membrane protein A and related proteins
D SpyM50858 ABC transporter permease protein K23535 nupB; general nucleoside transport system permease protein
D SpyM50859 ABC transporter permease protein K23536 nupC; general nucleoside transport system permease protein
D SpyM50857 ABC transporter ATP-binding protein K23537 nupA; general nucleoside transport system ATP-binding protein
D SpyM50843 pstS; putative phosphate ABC transporter,extracellular phosphate-binding lipoprotein K02040 pstS; phosphate transport system substrate-binding protein
D SpyM50844 pstC; putative phosphate ABC transporter permease protein K02037 pstC; phosphate transport system permease protein
D SpyM50845 putative phosphate ABC transporter permease protein K02038 pstA; phosphate transport system permease protein
D SpyM50847 pstB1; phosphate import ATP-binding protein 1 K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D SpyM50846 pstB2; phosphate import ATP-binding protein 2 K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D SpyM50789 putative glutamine ABC transporter,glutamine-binding protein/permease protein K10036 glnH; glutamine transport system substrate-binding protein
D SpyM50788 glnQ1; putative glutamine ABC transporter, ATP-binding protein 1 K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1]
D SpyM51102 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein
D SpyM51585 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein
D SpyM51101 transport system membrane protein K10009 tcyB; L-cystine transport system permease protein
D SpyM50428 ABC transporter permease protein K10009 tcyB; L-cystine transport system permease protein
D SpyM50429 ABC transporter ATP-binding protein K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1]
D SpyM51211 extracellular solute-binding protein K23059 artP; arginine/lysine/histidine transporter system substrate-binding protein
D SpyM50614 putative amino acid ABC transporter permease protein K17077 artQ; arginine/lysine/histidine transport system permease protein
D SpyM50615 glnQ3; putative glutamine transporter, ATP-binding protein 3 K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1]
D SpyM50215 glutamine ABC transporter, glutamine-binding protein/permease protein K17073 lysX1; putative lysine transport system substrate-binding protein
D SpyM50214 glnQ2; putative glutamine ABC transporter, ATP-binding protein 2 K17076 lysY; putative lysine transport system ATP-binding protein
D SpyM51584 putative lipoprotein K02073 metQ; D-methionine transport system substrate-binding protein
D SpyM51582 putative D-methionine transport system permease protein K02072 metI; D-methionine transport system permease protein
D SpyM51583 putative D-methionine transport system ATP-binding protein K02071 metN; D-methionine transport system ATP-binding protein
D SpyM50227 putative extracellular oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D SpyM50228 putative oligopeptide transporter permease protein K15581 oppB; oligopeptide transport system permease protein
D SpyM50229 putative oligopeptide transporter permease protein K15582 oppC; oligopeptide transport system permease protein
D SpyM50230 putative oligopeptide transporter ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein
D SpyM50231 putative oligopeptide transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein
D SpyM51680 lmb; laminin binding protein K09815 znuA; zinc transport system substrate-binding protein
D SpyM51261 adcA; zinc-binding protein AdcA precursor K09815 znuA; zinc transport system substrate-binding protein
D SpyM50077 ABC transporter permease protein K09816 znuB; zinc transport system permease protein
D SpyM50076 ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D SpyM51497 mtsA; metal ABC transporter substrate-binding lipoprotein precursor K11704 mtsA; iron/zinc/manganese/copper transport system substrate-binding protein
D SpyM51495 mtsC; metal cation ABC transporter membrane protein K11705 mtsC; iron/zinc/manganese/copper transport system permease protein
D SpyM51496 mtsB; metal cation ABC transporter ATP-binding protein K11706 mtsB; iron/zinc/manganese/copper transport system ATP-binding protein
D SpyM50159 BioY family protein K03523 bioY; biotin transport system substrate-specific component
D SpyM51816 putative cobalt transport protein K16785 ecfT; energy-coupling factor transport system permease protein
D SpyM50324 putative membrane protein K16785 ecfT; energy-coupling factor transport system permease protein
D SpyM51818 ABC transporter ATP-binding protein K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D SpyM51817 ABC transporter ATP-binding protein K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D SpyM51331 ftsX; putative cell division protein K09811 ftsX; cell division transport system permease protein
D SpyM51332 ftsE; putative cell division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein
D SpyM50175 ABC transporter ATP-binding membrane protein K18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump
D SpyM50176 ABC transporter ATP-binding membrane protein K18892 patB; ATP-binding cassette, subfamily B, multidrug efflux pump
D SpyM50920 ABC transporter ATP-binding membrane protein K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump
D SpyM50919 ABC transporter ATP-binding membrane protein K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump
C 02060 Phosphotransferase system (PTS) [PATH:spf02060]
D SpyM50740 pstI; phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
D SpyM50739 ptsH; histidine-containing phosphocarrier protein (HPr) K02784 ptsH; phosphocarrier protein HPr
D SpyM51662 putative glucose-specific phosphotransferase system (PTS), IIABC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208]
D SpyM50308 scrA; putative sucrose-specific phosphotransferase system (PTS), IIABC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211]
D SpyM51385 beta-glucoside-specific phosphotransferase system (PTS), IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-]
D SpyM51743 sugar phosphotransferase system (PTS), IIABC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201]
D SpyM51609 lacF; putative lactose-specific phosphotransferase system (PTS), IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207]
D SpyM51608 lacE; putative lactose-specific phosphotransferase system (PTS), IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207]
D SpyM50784 putative lactose/cellobiose-specific phosphotransferase system (PTS), IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D SpyM51709 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D SpyM50783 putative lactose/cellobiose-specific phosphotransferase system (PTS), IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]
D SpyM51708 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]
D SpyM51707 sugar phosphotransferase system (PTS), IIC component K02761 celB; cellobiose PTS system EIIC component
D SpyM50786 sugar phosphotransferase system (PTS), IIC component K02761 celB; cellobiose PTS system EIIC component
D SpyM50986 sugar phosphotransferase system (PTS),mannose/fructose family, IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D SpyM50366 manL; putative mannose-specific phosphotransferase system (PTS), IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191]
D SpyM50365 manM; putative mannose-specific phosphotransferase system (PTS), IIC component K02795 manY; mannose PTS system EIIC component
D SpyM50984 sugar phosphotransferase system (PTS),mannose/fructose family, IIC component K02795 manY; mannose PTS system EIIC component
D SpyM50364 manN; putative mannose-specific phosphotransferase system (PTS), IID component K02796 manZ; mannose PTS system EIID component
D SpyM50983 sugar phosphotransferase system (PTS),mannose/fructose family, IID component K02796 manZ; mannose PTS system EIID component
D SpyM50985 sugar phosphotransferase system (PTS),mannose/fructose family, IIB component K19507 gfrB; fructoselysine/glucoselysine PTS system EIIB component [EC:2.7.1.-]
D SpyM51340 putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-]
D SpyM51342 agaV; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-]
D SpyM51343 agaW; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component
D SpyM51344 agaD; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component
D SpyM50389 sugar phosphotransferase system (PTS), IIA component K20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204]
D SpyM50390 sugar phosphotransferase system (PTS), IIB component K20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204]
D SpyM50391 sugar phosphotransferase system (PTS),galactitol-specific family, IIC component K20114 gatC; galactose PTS system EIIC component
D SpyM50144 sugar phosphotransferase system (PTS), IIA component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]
D SpyM51637 putative PTS multi-domain regulator K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]
D SpyM50143 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D SpyM51636 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D SpyM51635 putative sugar-specific permease K03475 ulaA; ascorbate PTS system EIIC component
D SpyM50142 putative sugar-specific permease, SgaT/UlaA family K03475 ulaA; ascorbate PTS system EIIC component
D SpyM51146 fruA; putative fructose-specific phosphotransferase system (PTS), IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202]
D SpyM51147 fruK; putative 1-phosphofructokinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56]
C 03070 Bacterial secretion system [PATH:spf03070]
D SpyM51713 putative preprotein translocase SecE subunit K03073 secE; preprotein translocase subunit SecE
D SpyM51457 secG; putative protein-export membrane protein K03075 secG; preprotein translocase subunit SecG
D SpyM50064 secY; preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY
D SpyM51649 putative preprotein translocase subunit K03210 yajC; preprotein translocase subunit YajC
D SpyM51561 membrane protein OxaA 2 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
D SpyM50188 membrane protein OxaA 1 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
D SpyM50312 secA; putative preprotein SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D SpyM51388 ftsY; putative cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor
D SpyM50883 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:spf02020]
D SpyM50843 pstS; putative phosphate ABC transporter,extracellular phosphate-binding lipoprotein K02040 pstS; phosphate transport system substrate-binding protein
D SpyM51837 htrA; serine protease K04771 degP; serine protease Do [EC:3.4.21.107]
D SpyM51428 vicK; sensor histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
D SpyM51429 vicR; response regulator protein K07668 vicR; two-component system, OmpR family, response regulator VicR
D SpyM50001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein
D SpyM50792 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
D SpyM50793 dltB; putative activated D-alanine transport protein K03739 dltB; membrane protein involved in D-alanine export
D SpyM50794 dltC; D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
D SpyM50795 dltD; putative D-alanyl-lipoteichoic acid biosynthesis protein K03740 dltD; D-alanine transfer protein
D SpyM50851 ciaH; sensor histidine kinase K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
D SpyM50850 ciaR; response regulator protein K14983 ciaR; two-component system, OmpR family, response regulator CiaR
D SpyM50343 putative D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
D SpyM51572 csrS; sensor histidine kinase K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]
D SpyM51573 csrR; response regulator protein K18941 arlR; two-component system, OmpR family, response regulator ArlR
D SpyM51687 sensor histidine kinase K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3]
D SpyM51688 response regulator protein K18987 irr; two-component system, OmpR family, response regulator Irr
D SpyM50887 citC; putative Citrate [pro-3S]-lyase] ligase K01910 citC; [citrate (pro-3S)-lyase] ligase [EC:6.2.1.22]
D SpyM50892 citD; putative citrate lyase acyl carrier protein K01646 citD; citrate lyase subunit gamma (acyl carrier protein)
D SpyM50891 citE; putative citrate lyase beta subunit K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34]
D SpyM50890 citF; putative citrate lyase alpha subunit K01643 citF; citrate lyase subunit alpha / citrate CoA-transferase [EC:2.8.3.10]
D SpyM50889 citX; puatative apo-citrate lyase phosphoribosyl-dephospho-CoA transferase K05964 citX; holo-ACP synthase [EC:2.7.7.61]
D SpyM50899 citG; putative 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]
D SpyM50955 NAD-dependent malic enzyme K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
D SpyM50956 malP; sodium-dependent malate transporter K11616 maeN; malate:Na+ symporter
D SpyM50537 putative sensor kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D SpyM50183 fasB; sensor histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D SpyM50186 fasA; response regulator protein K07707 agrA; two-component system, LytTR family, response regulator AgrA
D SpyM50236 comX1; putative competence-specific global transcription modulator K12296 comX1_2; competence protein ComX
D SpyM51595 comX2; putative competence-specific global transcription modulator 2 K12296 comX1_2; competence protein ComX
D SpyM50010 putative exported protein K01467 ampC; beta-lactamase class C [EC:3.5.2.6]
D SpyM50458 sensor histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
D SpyM50459 response regulator protein K11618 liaR; two-component system, NarL family, response regulator LiaR
D SpyM51602 salK; sensor histidine kinase K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK
D SpyM51601 salR; response regulator protein K14989 salR; two-component system, NarL family, secretion system response regulator SalR
D SpyM50255 glnA; putative glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SpyM50115 atoD1; acetate CoA-transferase alpha subunit 1 K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
D SpyM50446 atoD2; acetate CoA-transferase alpha subunit 2 K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
D SpyM50116 atoA1; acetate CoA-transferase beta subunit 1 K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]
D SpyM50112 putative short-chain fatty acids transporter K02106 atoE; short-chain fatty acids transporter
D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM50549 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
D SpyM50572 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
D SpyM50981 response regulator protein K07720 yesN; two-component system, response regulator YesN
D SpyM50550 response regulator protein K07720 yesN; two-component system, response regulator YesN
D SpyM50036 putative phosphotyrosine protein phosphatase K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:spf02024]
D SpyM50442 luxS; S-ribosylhomocysteinase K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]
D SpyM51668 trpG; anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D SpyM51431 hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SpyM50537 putative sensor kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D SpyM50183 fasB; sensor histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D SpyM50186 fasA; response regulator protein K07707 agrA; two-component system, LytTR family, response regulator AgrA
D SpyM50136 slo; streptolysin O precursor (thiol-activated cytolysin) K11031 slo; thiol-activated cytolysin
D SpyM50851 ciaH; sensor histidine kinase K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
D SpyM50850 ciaR; response regulator protein K14983 ciaR; two-component system, OmpR family, response regulator CiaR
D SpyM50227 putative extracellular oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D SpyM50228 putative oligopeptide transporter permease protein K15581 oppB; oligopeptide transport system permease protein
D SpyM50229 putative oligopeptide transporter permease protein K15582 oppC; oligopeptide transport system permease protein
D SpyM50230 putative oligopeptide transporter ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein
D SpyM50231 putative oligopeptide transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein
D SpyM50034 putative DNA-binding protein K20342 comR; HTH-type transcriptional regulator, regulator for ComX
D SpyM50236 comX1; putative competence-specific global transcription modulator K12296 comX1_2; competence protein ComX
D SpyM51595 comX2; putative competence-specific global transcription modulator 2 K12296 comX1_2; competence protein ComX
D SpyM51462 putative DNA-binding protein K20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator
D SpyM51424 putative regulatory protein K20374 rgg3; HTH-type transcriptional regulator, SHP3-responsive repressor
D SpyM51673 dppA; dipeptide-binding extracellular protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SpyM51674 dppB; dipeptide transport system permease protein DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SpyM51675 dppC; dipeptide transport system permease protein DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SpyM51676 dppD; dipeptide transport system ATP-binding protein DppD K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SpyM51677 dppE; dipeptide transport system ATP-binding protein DppF K02032 ddpF; peptide/nickel transport system ATP-binding protein
D SpyM51701 ropB; transcriptional regulator K20375 ropB; HTH-type transcriptional regulator, pheromone-responsive regulator
D SpyM51698 speB; Streptopain precursor K01364 speB; streptopain [EC:3.4.22.10]
D SpyM50395 lacD1; tagatose 1,6-diphosphate aldolase 1 K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40]
D SpyM51610 lacD2; tagatose 1,6-diphosphate aldolase 2 K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40]
D SpyM51561 membrane protein OxaA 2 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
D SpyM50188 membrane protein OxaA 1 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
D SpyM51713 putative preprotein translocase SecE subunit K03073 secE; preprotein translocase subunit SecE
D SpyM51457 secG; putative protein-export membrane protein K03075 secG; preprotein translocase subunit SecG
D SpyM50064 secY; preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY
D SpyM51649 putative preprotein translocase subunit K03210 yajC; preprotein translocase subunit YajC
D SpyM50312 secA; putative preprotein SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D SpyM51388 ftsY; putative cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor
D SpyM50883 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly [PATH:spf02040]
D SpyM51102 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein
D SpyM51585 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein
D SpyM51207 rpoD; RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D SpyM51248 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
D SpyM50104 putative surface-anchored protein K13734 sfb1; fibronectin-binding protein 1
D SpyM50110 protein F2 like fibronectin-binding protein K13734 sfb1; fibronectin-binding protein 1
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance [PATH:spf01501]
D SpyM50010 putative exported protein K01467 ampC; beta-lactamase class C [EC:3.5.2.6]
D SpyM50227 putative extracellular oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D SpyM50228 putative oligopeptide transporter permease protein K15581 oppB; oligopeptide transport system permease protein
D SpyM50229 putative oligopeptide transporter permease protein K15582 oppC; oligopeptide transport system permease protein
D SpyM50230 putative oligopeptide transporter ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein
D SpyM50231 putative oligopeptide transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein
D SpyM50436 pbp1A; putative penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D SpyM50080 pbp1B; putative penicillin-binding protein 1B K03693 pbp1b; penicillin-binding protein 1B
D SpyM51715 pbp2A; penicillin-binding protein 2a K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4]
D SpyM50425 pbpX; putative penicillin binding protein 2x K12556 pbp2X; penicillin-binding protein 2X
C 01502 Vancomycin resistance [PATH:spf01502]
D SpyM50702 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D SpyM50314 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D SpyM50703 murF; putative UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D SpyM50426 mraY; phospho-N-acetylmuramoyl-pentapeptide-transfera se K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D SpyM50600 murG; putative UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyr ophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D SpyM50343 putative D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:spf01503]
D SpyM51837 htrA; serine protease K04771 degP; serine protease Do [EC:3.4.21.107]
D SpyM51494 putative cyclophilin type peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D SpyM50792 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
D SpyM50793 dltB; putative activated D-alanine transport protein K03739 dltB; membrane protein involved in D-alanine export
D SpyM50794 dltC; D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
D SpyM50795 dltD; putative D-alanyl-lipoteichoic acid biosynthesis protein K03740 dltD; D-alanine transfer protein
D SpyM51698 speB; Streptopain precursor K01364 speB; streptopain [EC:3.4.22.10]
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:spf01000]
C 01001 Protein kinases [BR:spf01001]
D SpyM50456 stk1; serine/threonine-protein kinase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D SpyM51428 vicK; sensor histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
D SpyM50851 ciaH; sensor histidine kinase K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
D SpyM51572 csrS; sensor histidine kinase K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]
D SpyM51687 sensor histidine kinase K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3]
D SpyM50458 sensor histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
D SpyM51602 salK; sensor histidine kinase K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK
D SpyM50957 putative sensor kinase K02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3]
D SpyM50537 putative sensor kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D SpyM50183 fasB; sensor histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D SpyM50549 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
D SpyM50572 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:spf01009]
D SpyM50812 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D SpyM50455 putative protein phosphatase K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16]
C 01002 Peptidases and inhibitors [BR:spf01002]
D SpyM51170 lspA; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
D SpyM50435 pepC; aminopeptidase C K01372 BLMH; bleomycin hydrolase [EC:3.4.22.40]
D SpyM51698 speB; Streptopain precursor K01364 speB; streptopain [EC:3.4.22.10]
D SpyM51453 pcp; pyrrolidone-carboxylate peptidase K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3]
D SpyM50879 guaA; GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D SpyM50947 putative peptidase K07010 K07010; putative glutamine amidotransferase
D SpyM50015 putative amidase K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
D SpyM50023 purF; putative amidophosphoribosyltransferase precursor K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D SpyM50815 glmS; glucosamine--fructose-6-phosphate aminotransferase [isomerizing] K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D SpyM50915 srtA; sortase A K07284 srtA; sortase A [EC:3.4.22.70]
D SpyM50107 srtB; sortase B K08600 srtB; sortase B [EC:3.4.22.71]
D SpyM50730 CAAX amino terminal protease family membrane protein K07052 K07052; CAAX protease family protein
D SpyM51243 sagE; CAAX amino terminal protease family protein K07052 K07052; CAAX protease family protein
D SpyM50849 pepN; putative lysyl-aminopeptidase K01256 pepN; aminopeptidase N [EC:3.4.11.2]
D SpyM50722 pepB; putative oligopeptidase K08602 pepF; oligoendopeptidase F [EC:3.4.24.-]
D SpyM51741 pepO; putative endopeptidase O K07386 pepO; putative endopeptidase [EC:3.4.24.-]
D SpyM50343 putative D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
D SpyM50976 pepV; putative Xaa-His dipeptidase K01274 pepV; beta-Ala-Xaa dipeptidase [EC:3.4.13.-]
D SpyM51192 pepT; peptidase T K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]
D SpyM50756 putative metallopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D SpyM51447 pepQ; putative Xaa-Pro dipeptidase K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]
D SpyM50301 putative metallopeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D SpyM50013 ftsH; putative cell division protease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D SpyM50095 pepA; putative glutamyl-aminopeptidase K01261 pepA; glutamyl aminopeptidase [EC:3.4.11.7]
D SpyM51575 htpX; probable protease HtpX homolog K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D SpyM51646 eep; putative pheromone-processing membrane metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
D SpyM51837 htrA; serine protease K04771 degP; serine protease Do [EC:3.4.21.107]
D SpyM51518 prtS; putative cell surface protease K01361 E3.4.21.96; lactocepin [EC:3.4.21.96]
D SpyM51681 scpA; C5A peptidase precursor K08652 C5AP; C5a peptidase [EC:3.4.21.110]
D SpyM50971 putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D SpyM50226 putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D SpyM51530 clpP; putative ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
D SpyM50273 pepXP; Xaa-Pro dipeptidyl-peptidase K01281 pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11]
D SpyM50587 putative exported protein K07177 K07177; Lon-like protease
D SpyM50884 putative phage repressor-like protein K01356 lexA; repressor LexA [EC:3.4.21.88]
D SpyM50285 spi; putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D SpyM50814 sipC; putative signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D SpyM50105 putative signal peptidase K03100 lepB; signal peptidase I [EC:3.4.21.89]
D SpyM51397 putative microcin immunity protein K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]
D SpyM51371 putative peptidase K08303 prtC; U32 family peptidase [EC:3.4.-.-]
C 01003 Glycosyltransferases [BR:spf01003]
D SpyM51444 putative glycosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]
D SpyM51824 hasA; hyaluronan synthase K00752 hasA; hyaluronan synthase [EC:2.4.1.212]
D SpyM51445 putative glycosyltransferase K13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208]
D SpyM50436 pbp1A; putative penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D SpyM50080 pbp1B; putative penicillin-binding protein 1B K03693 pbp1b; penicillin-binding protein 1B
D SpyM51715 pbp2A; penicillin-binding protein 2a K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4]
D SpyM50219 rgpG; putative glycosyl transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]
C 01005 Lipopolysaccharide biosynthesis proteins [BR:spf01005]
D SpyM51203 putative rhamnosyltransferase K12996 rgpA; rhamnosyltransferase [EC:2.4.1.-]
D SpyM51202 putative glycosyltransferase K12997 rgpB; rhamnosyltransferase [EC:2.4.1.-]
D SpyM51199 putative glycosyltransferase K12998 rgpE; glucosyltransferase [EC:2.4.1.-]
D SpyM51198 rhamnan synthesis protein F family protein K07272 rgpF; rhamnosyltransferase [EC:2.4.1.-]
D SpyM50219 rgpG; putative glycosyl transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]
D SpyM51450 csbB; putative glucosyl transferase K12999 rgpI; glucosyltransferase [EC:2.4.1.-]
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:spf01011]
D SpyM51224 murA1; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D SpyM50752 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D SpyM50963 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D SpyM51565 murC; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D SpyM50599 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D SpyM51533 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-dia minopimelate ligase K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7]
D SpyM50702 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D SpyM50878 murM; putative peptidoglycan branched peptide synthesis protein MurM K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10]
D SpyM51352 murM; putative peptidoglycan pentaglycine interpeptide biosynthesis protein K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10]
D SpyM51353 murN; putative peptidoglycan branched peptide synthesis protein K12554 murN; alanine adding enzyme [EC:2.3.2.-]
D SpyM50314 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D SpyM51555 glr; glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3]
D SpyM51397 putative microcin immunity protein K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]
D SpyM50426 mraY; phospho-N-acetylmuramoyl-pentapeptide-transfera se K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D SpyM50600 murG; putative UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyr ophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D SpyM50217 bacA; undecaprenol kinase (bacitracin resistance protein) K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D SpyM51544 PAP2 superfamily protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]
D SpyM50436 pbp1A; putative penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D SpyM50080 pbp1B; putative penicillin-binding protein 1B K03693 pbp1b; penicillin-binding protein 1B
D SpyM51715 pbp2A; penicillin-binding protein 2a K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4]
D SpyM50425 pbpX; putative penicillin binding protein 2x K12556 pbp2X; penicillin-binding protein 2X
D SpyM50971 putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D SpyM50226 putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D SpyM50343 putative D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
D SpyM50015 putative amidase K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
D SpyM50915 srtA; sortase A K07284 srtA; sortase A [EC:3.4.22.70]
D SpyM50107 srtB; sortase B K08600 srtB; sortase B [EC:3.4.22.71]
D SpyM51563 putative aminodeoxychorismate lyase K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]
C 01004 Lipid biosynthesis proteins [BR:spf01004]
D SpyM50354 fabD; putative malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D SpyM50351 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D SpyM50356 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D SpyM51506 putative short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SpyM50355 fabG; 3-oxoacyl-[acyl-carrier protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SpyM50358 fabZ; (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D SpyM50353 fabK; enoyl-ACP reductase K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
D SpyM50349 enoyl-CoA hydratase/isomerase family protein K18474 fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14]
D SpyM51431 hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SpyM50018 plsX; fatty acid/phospholipid synthesis protein K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D SpyM51098 putative membrane protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D SpyM50710 putative acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:spf01006]
D SpyM50622 fps; putative geranyltranstransferase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D SpyM51648 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D SpyM51085 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
C 01007 Amino acid related enzymes [BR:spf01007]
D SpyM50182 gltX; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
D SpyM50079 tyrS; putative tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D SpyM51831 trsA; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D SpyM51628 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D SpyM51783 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D SpyM51515 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D SpyM50609 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D SpyM50564 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D SpyM50141 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D SpyM51368 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D SpyM51788 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D SpyM51326 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D SpyM51789 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D SpyM50405 glyQ; glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D SpyM50406 glyS; glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D SpyM50362 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D SpyM51645 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D SpyM51443 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D SpyM50726 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D SpyM51220 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D SpyM51219 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D SpyM50332 putative aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]
D SpyM51094 putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D SpyM51667 putative chorismate binding enzyme K03342 pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins [BR:spf00194]
D SpyM51226 atpC; ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D SpyM51227 atpD; ATP synthase beta chain K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D SpyM51228 atpG; ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D SpyM51229 atpA; ATP synthase alpha chain K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D SpyM51230 atpH; putative ATP synthase delta chain K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D SpyM51231 atpF; ATP synthase B chain K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D SpyM51233 atpE; ATP synthase C chain K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D SpyM51232 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:spf03000]
D SpyM51614 lacR2; lactose phosphotransferase system repressor 2 K02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor
D SpyM50388 lacR1; lactose phosphotransferase system repressor 1 K02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor
D SpyM51148 DeoR family regulatory protein K03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor
D SpyM50588 LacI family regulatory protein K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D SpyM50803 LacI family transcriptional repressor K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D SpyM51446 ccpA; catabolite control protein A K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D SpyM51346 LacI family regulatory protein K02525 kdgR; LacI family transcriptional regulator, kdg operon repressor
D SpyM50306 scrR; putative sucrose operon repressor K03484 scrR; LacI family transcriptional regulator, sucrose operon repressor
D SpyM50540 GntR family regulatory protein K02103 araR; GntR family transcriptional regulator, arabinose operon transcriptional repressor
D SpyM51744 GntR family regulatory protein K03486 treR2; GntR family transcriptional regulator, trehalose operon transcriptional repressor
D SpyM50881 GntR family regulatory protein K24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator
D SpyM51260 GntR family regulatory protein K24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator
D SpyM50254 glnR; MerR family regulatory protein K03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor
D SpyM50154 ferric uptake regulator family protein K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator
D SpyM50576 Crp family regulatory protein K21828 arcR; CRP/FNR family transcriptional regulator, arginine deiminase pathway regulator
D SpyM51793 cadC; putative cadmium efflux system accessory protein K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor
D SpyM51800A PadR family regulatory protein K10947 K10947; PadR family transcriptional regulator
D SpyM51498 scaR; metal-dependent transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D SpyM50749 birA; BirA bifunctional protein [includes: biotin operon repressor; biotin--[acetyl-CoA-carboxylase] synthetase] K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D SpyM50034 putative DNA-binding protein K20342 comR; HTH-type transcriptional regulator, regulator for ComX
D SpyM51462 putative DNA-binding protein K20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator
D SpyM51424 putative regulatory protein K20374 rgg3; HTH-type transcriptional regulator, SHP3-responsive repressor
D SpyM51701 ropB; transcriptional regulator K20375 ropB; HTH-type transcriptional regulator, pheromone-responsive regulator
D SpyM50207 purR; putative pur operon repressor K09685 purR; HTH-type transcriptional regulator, purine operon repressor
D SpyM50946 rex; putative redox-sensing transcriptional repressor K01926 rex; redox-sensing transcriptional repressor
D SpyM50333 codY; GTP-sensing transcriptional pleiotropic repressor K03706 codY; transcriptional pleiotropic repressor
D SpyM50478 putative DNA-binding phage protein K07727 K07727; putative transcriptional regulator
D SpyM51621 putative DNA-binding protein K07729 K07729; putative transcriptional regulator
D SpyM50728 putative DNA-binding protein K07729 K07729; putative transcriptional regulator
D SpyM51317 putative phage repressor protein K07729 K07729; putative transcriptional regulator
D SpyM51386 licT; transcription antiterminator K03488 licT; beta-glucoside operon transcriptional antiterminator
D SpyM50148 putative transcriptional antiterminator K03493 bglG1; transcriptional antiterminator
D SpyM50782 putative regulatory protein K03491 licR; probable licABCH operon transcriptional regulator
D SpyM51838 putative chromosome partitioning protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D SpyM50575 argR; arginine repressor K03402 argR; transcriptional regulator of arginine metabolism
D SpyM50624 putative repressor protein K03402 argR; transcriptional regulator of arginine metabolism
D SpyM51782 argR; putative arginine repressor K03402 argR; transcriptional regulator of arginine metabolism
D SpyM50345 hrcA; heat-inducible transcription repressor HrcA K03705 hrcA; heat-inducible transcriptional repressor
D SpyM51724 ctsR; transcriptional regulator K03708 ctsR; transcriptional regulator of stress and heat shock response
D SpyM51168 pyrR; PyrR bifunctional protein [includes: pyrimidine operon regulatory protein; uracil phosphoribosyltransferase] K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]
D SpyM51571 ATP-binding protein K07738 nrdR; transcriptional repressor NrdR
D SpyM50236 comX1; putative competence-specific global transcription modulator K12296 comX1_2; competence protein ComX
D SpyM51595 comX2; putative competence-specific global transcription modulator 2 K12296 comX1_2; competence protein ComX
C 03021 Transcription machinery [BR:spf03021]
D SpyM50069 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D SpyM50081 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D SpyM50082 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D SpyM50243 rpoE; putative DNA-directed RNA polymerase, delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
D SpyM50451 rpoZ; DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D SpyM51207 rpoD; RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor
D SpyM50379 nusA; putative N utilization substance protein A K02600 nusA; transcription termination/antitermination protein NusA
D SpyM50305 nusB; N utilization substance protein B homolog (NusB protein) K03625 nusB; transcription antitermination protein NusB
D SpyM50133 nusG; transcription antitermination factor K02601 nusG; transcription termination/antitermination protein NusG
D SpyM51562 greA; transcription elongation factor K03624 greA; transcription elongation factor GreA
C 03019 Messenger RNA biogenesis [BR:spf03019]
D SpyM51426 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D SpyM50256 metallo-beta-lactamase superfamily protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D SpyM51012 metallo-beta-lactamase superfamily protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D SpyM50449 putative phosphohydrolase K18682 rny; ribonucrease Y [EC:3.1.-.-]
D SpyM51456 rnr; putative exoribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D SpyM50206 putative 3'-5' exoribonuclease K03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-]
D SpyM50706 DEAD box helicase family protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D SpyM50427 mraW; putative helicase K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7]
D SpyM51248 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D SpyM51633 pnpA; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D SpyM50812 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D SpyM50347 dnaK; chaperone protein DnaK (heat shock protein 70) K04043 dnaK; molecular chaperone DnaK
D SpyM51721 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D SpyM51325 P-loop ATPase protein family protein K06958 rapZ; RNase adapter protein RapZ
C 03041 Spliceosome
C 03011 Ribosome [BR:spf03011]
D SpyM51092 putative 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D SpyM51739 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D SpyM50050 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D SpyM51805 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D SpyM50061 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D SpyM50295 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D SpyM50210 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D SpyM50058 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D SpyM51619 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D SpyM50043 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D SpyM50068 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D SpyM50209 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D SpyM50067 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D SpyM50057 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D SpyM50261 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D SpyM51638 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D SpyM51159 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D SpyM50053 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D SpyM50297 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D SpyM50048 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D SpyM50852 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D SpyM51210 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D SpyM51490 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D SpyM50047 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D SpyM50044 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D SpyM50045 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D SpyM50056 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D SpyM50059 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D SpyM51808 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D SpyM50973 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D SpyM51491 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D SpyM50972 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D SpyM51620 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D SpyM50054 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D SpyM50063 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D SpyM50051 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D SpyM50070 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D SpyM50060 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D SpyM51253 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D SpyM51186 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D SpyM51174 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D SpyM50049 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D SpyM50046 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D SpyM50055 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D SpyM51172 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D SpyM50247 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D SpyM50052 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D SpyM50062 rpmD; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D SpyM51258 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D SpyM51790 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D SpyM51714 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D SpyM51791 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D SpyM51458A rpmGB; 50S ribosomal protein L33 2 K02913 RP-L33; large subunit ribosomal protein L33
D SpyM50190 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D SpyM51187 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D SpyM50066A rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D 5S_rRNA-1 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D 5S_rRNA-3 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D 5S_rRNA-2 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D 5S_rRNA-4 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D 5S_rRNA-5 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D 5S_rRNA-6 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D 16S_rRNA-1 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 16S_rRNA-3 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 16S_rRNA-6 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 16S_rRNA-2 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 16S_rRNA-4 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 16S_rRNA-5 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 23S_rRNA-2 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 23S_rRNA-1 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 23S_rRNA-3 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 23S_rRNA-4 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 23S_rRNA-5 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 23S_rRNA-6 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:spf03009]
D SpyM51426 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D SpyM51478 era; GTP-binding protein Era homolog K03595 era; GTPase
D SpyM50777 putative GTP-binding protein K03979 obgE; GTPase [EC:3.6.5.-]
D SpyM50379 nusA; putative N utilization substance protein A K02600 nusA; transcription termination/antitermination protein NusA
D SpyM50305 nusB; N utilization substance protein B homolog (NusB protein) K03625 nusB; transcription antitermination protein NusB
D SpyM50133 nusG; transcription antitermination factor K02601 nusG; transcription termination/antitermination protein NusG
D SpyM50719 putative ribosomal small subunit pseudouridine synthase A K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]
D SpyM50768 putative ribosomal small subunit pseudouridine synthase B K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]
D SpyM50201 ksgA; dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D SpyM50454 putative ribosomal RNA small subunit methyltransferase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]
D SpyM50854 putative methyltransferase K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]
D SpyM50585 putative methylase K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]
D SpyM51663 conserved hypothetical protein K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]
D SpyM51577 gidB; methyltransferase GidB K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D SpyM50423 mraW; S-adenosyl-methyltransferase MraW K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
D SpyM51524 tetrapyrrole (corrin/porphyrin) methylase family protein K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]
D SpyM50623 hemolysin-like protein K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]
D SpyM51625 SpoU rRNA methylase family protein K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]
D SpyM51836 conserved hypothetical protein K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]
D SpyM51184 conserved hypothetical protein K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]
D SpyM50591 radical SAM superfamily protein K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]
D SpyM50761 putative RNA methyltransferase K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]
D SpyM51548 rluB; ribosomal large subunit pseudouridine synthase B K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]
D SpyM51169 putative RNA pseudouridylate synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D SpyM50939 putative RNA pseudouridylate synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D SpyM51717 RNA pseudouridylate synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D SpyM50259 acetyltransferase (GNAT) family protein K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D SpyM51153 rimM; 16S rRNA processing protein K02860 rimM; 16S rRNA processing protein RimM
D SpyM51664 ribosomal protein L11 methyltransferase K02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]
D SpyM51755 putative Holliday junction resolvase K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]
D SpyM51627 conserved hypothetical protein K11145 mrnC; mini-ribonuclease III [EC:3.1.26.-]
D SpyM50706 DEAD box helicase family protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D SpyM50427 mraW; putative helicase K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7]
D SpyM50202 engC; probable GTPase EngC K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]
D SpyM51568 engA; GTP-binding protein EngA K03977 engA; GTPase
D SpyM50908 putative GTPase protein K14540 rbgA; ribosome biogenesis GTPase A
D SpyM51084 putative GTPase K03665 hflX; GTPase
D SpyM51593 GTP-binding protein K06948 yqeH; 30S ribosome assembly GTPase
D SpyM50925 conserved hypothetical protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D SpyM51658 relA; GTP pyrophosphokinase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D SpyM50383 rbfA; ribosome-binding factor A K02834 rbfA; ribosome-binding factor A
D SpyM50378 conserved hypothetical protein K09748 rimP; ribosome maturation factor RimP
D SpyM51827 conserved hypothetical protein K14761 rlbA; ribosome-associated protein
D SpyM51589 conserved hypothetical protein K09710 ybeB; ribosome-associated protein
D SpyM51480 conserved hypothetical protein K07042 ybeY; probable rRNA maturation factor
D SpyM51592 conserved hypothetical protein K07574 yhbY; RNA-binding protein
D SpyM50466 sigma 54 modulation protein / S30EA ribosomal protein K05808 hpf; ribosome hibernation promoting factor
D SpyM50004 putative GTP-binding protein K06942 ychF; ribosome-binding ATPase
D SpyM51574 conserved hypothetical protein K07040 yceD; DUF177 domain-containing protein
C 03016 Transfer RNA biogenesis [BR:spf03016]
D SpyM51082 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D SpyM51134 cca; CCA-adding enzyme K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
D SpyM51645 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D SpyM50609 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D SpyM50141 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D SpyM51515 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D SpyM51783 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D SpyM51368 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D SpyM51788 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D SpyM50726 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D SpyM51326 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D SpyM51443 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D SpyM50362 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D SpyM51628 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D SpyM50564 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D SpyM51789 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D SpyM51220 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D SpyM51219 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D SpyM50079 tyrS; putative tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D SpyM51831 trsA; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D SpyM51657 D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D SpyM50373 HIT-family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D SpyM50377 tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D SpyM50237 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D SpyM50837 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D SpyM51177 putative cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SpyM50944 putative cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SpyM50925 conserved hypothetical protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D SpyM51085 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D SpyM50975 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D SpyM51810 gidA; glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D SpyM50187 rnpA; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D SpyM50405 glyQ; glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D SpyM50406 glyS; glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D SpyM50182 gltX; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
D SpyM51365 conserved hypothetical protein K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
D SpyM50161 putative deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
D SpyM50101 putative tRNA-dihydrouridine synthase K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D SpyM50904 protein Gid homolog K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]
D SpyM51152 trmD; tRNA (Guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D SpyM51076 conserved hypothetical protein K06967 trmK; tRNA (adenine22-N1)-methyltransferase [EC:2.1.1.217]
D SpyM51546 SpoU rRNA methylase family protein K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D SpyM51559 SpoU rRNA Methylase family protein K03437 spoU; RNA methyltransferase, TrmH family
D SpyM51812 putative tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D SpyM50717 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D SpyM51334 putative iron-sulphur protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D SpyM50177 conserved hypothetical protein K09765 queH; epoxyqueuosine reductase [EC:1.17.99.6]
D SpyM50157 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D SpyM51176 thiI; putative thiamine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D SpyM50011 PP-loop family protein K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D SpyM50258 glycoprotease family protein K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D SpyM50260 putative glycoprotease K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D SpyM50369 putative P-loop hydrolase K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D SpyM51587 conserved hypothetical protein K27343 tmcAL; tRNA(Met) cytidine acetate ligase [EC:6.3.4.-]
D SpyM51456 rnr; putative exoribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D SpyM51633 pnpA; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C 03012 Translation factors [BR:spf03012]
D SpyM50382 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D SpyM51188 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D SpyM51009 ABC transporter ATP-binding protein K06158 ABCF3; ATP-binding cassette, subfamily F, member 3
D SpyM51740 tsf; elongation factor Ts K02357 tsf; elongation factor Ts
D SpyM51355 tufA; elongation factor Tu (EF-Tu) K02358 tuf; elongation factor Tu
D SpyM50211 fus; elongation factor G (EF-G) K02355 fusA; elongation factor G
D SpyM50927 prfA; peptide chain release factor 1 K02835 prfA; peptide chain release factor 1
D SpyM51488 rrf; ribosome recycling factor K02838 frr; ribosome recycling factor
D SpyM50926 putative methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D SpyM50005 pth; peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]
D SpyM50066 infA; translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1
D SpyM50303 efp; elongation factor P (EF-P) K02356 efp; elongation factor P
D SpyM51333 prfB; peptide chain release factor 2 K02836 prfB; peptide chain release factor 2
D SpyM50705 prfC; peptide chain release factor 3 K02837 prfC; peptide chain release factor 3
C 03110 Chaperones and folding catalysts [BR:spf03110]
D SpyM51723 clpC; putative stress response-related Clp ATPase K03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC
D SpyM50612 clpE; putative ATP-dependent Clp protease ATP-binding subunit K03697 clpE; ATP-dependent Clp protease ATP-binding subunit ClpE
D SpyM51114 clpL; putative ATP-dependent protease ATP-binding subunit ClpL K04086 clpL; ATP-dependent Clp protease ATP-binding subunit ClpL
D SpyM51117 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
D SpyM50347 dnaK; chaperone protein DnaK (heat shock protein 70) K04043 dnaK; molecular chaperone DnaK
D SpyM51721 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D SpyM50348 dnaJ; chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D SpyM50102 33 kDa chaperonin (heat shock protein 33 homolog) K04083 hslO; molecular chaperone Hsp33
D SpyM50346 grpE; GrpE protein (HSP-70 cofactor) K03687 GRPE; molecular chaperone GrpE
D SpyM51722 groES; 10 kDa chaperonin K04078 groES; chaperonin GroES
D SpyM51837 htrA; serine protease K04771 degP; serine protease Do [EC:3.4.21.107]
D SpyM50013 ftsH; putative cell division protease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D SpyM51232 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D SpyM51518 prtS; putative cell surface protease K01361 E3.4.21.96; lactocepin [EC:3.4.21.96]
D SpyM51681 scpA; C5A peptidase precursor K08652 C5AP; C5a peptidase [EC:3.4.21.110]
D SpyM51494 putative cyclophilin type peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D SpyM50460 cyclophilin type peptidyl-prolyl cis-trans isomerase protein K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D SpyM51695 prsA2; foldase protein PrsA 2 precursor K07533 prsA; foldase protein PrsA [EC:5.2.1.8]
D SpyM50725 prsA1; foldase protein PrsA 1 precursor K07533 prsA; foldase protein PrsA [EC:5.2.1.8]
D SpyM50291 putative thioredoxin K03671 TXN; thioredoxin
C 04131 Membrane trafficking [BR:spf04131]
D SpyM50538 glycosyl hydrolases family protein K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
D SpyM50212 plr; glyceraldehyde-3-phosphate dehydrogenase,plasmin receptor K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D SpyM50696 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D SpyM50813 pyk; putative pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
C 04121 Ubiquitin system
C 03051 Proteasome
C 03032 DNA replication proteins [BR:spf03032]
D SpyM50630 hlpA; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SpyM50001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein
D SpyM51807 dnaC; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D SpyM50482 putative phage DNA replication protein K02315 dnaC; DNA replication protein DnaC
D SpyM51208 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D SpyM51570 replication initiation and membrane attachment protein K03346 dnaB; replication initiation and membrane attachment protein
D SpyM51569 dnaI; putative primosomal protein K11144 dnaI; primosomal protein DnaI
D SpyM50296 ssb; single strand binding protein (SSB) K03111 ssb; single-strand DNA-binding protein
D SpyM50099 putative single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SpyM50811 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D SpyM51644 polC; DNA polymerase III PolC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
D SpyM50002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D SpyM50713 putative DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D SpyM51527 holB; putative DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D SpyM50268 putative exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D SpyM50748 dnaH; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D SpyM50907 rnh; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D SpyM50286 ribonuclease HIII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4]
D SpyM50152 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D SpyM51235 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D SpyM50916 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D SpyM51251 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D SpyM51095 parC; topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D SpyM51097 parE; topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D SpyM50905 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:spf03036]
D SpyM51426 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D SpyM50630 hlpA; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SpyM50001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein
D SpyM50593 dpr; Dps-like peroxide resistance protein Dpr K04047 dps; starvation-inducible DNA-binding protein
D SpyM51425 smc; putative chromosome partition protein K03529 smc; chromosome segregation protein
D SpyM51550 scpA; segregation and condensation protein A K05896 scpA; segregation and condensation protein A
D SpyM51549 scpB; segregation and condensation protein B K06024 scpB; segregation and condensation protein B
D SpyM50602 ftsA; putative cell division protein K03590 ftsA; cell division protein FtsA
D SpyM50008 putative septum formation initiator protein K13052 divIC; cell division protein DivIC
D SpyM51332 ftsE; putative cell division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein
D SpyM51493 DNA translocase FtsK K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family
D SpyM50424 ftsL; putative cell division protein K03586 ftsL; cell division protein FtsL
D SpyM50601 putative cell division protein K03589 ftsQ; cell division protein FtsQ
D SpyM51357 ftsW; putative cell division protein K03588 ftsW; cell division protein FtsW
D SpyM51331 ftsX; putative cell division protein K09811 ftsX; cell division transport system permease protein
D SpyM50603 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D SpyM51250 ezrA; septation ring formation regulator K06286 ezrA; septation ring formation regulator
D SpyM50608 putative cell-division protein DivIVA K04074 divIVA; cell division initiation protein
D SpyM50605 conserved hypothetical protein K09772 sepF; cell division inhibitor SepF
D SpyM51838 putative chromosome partitioning protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D SpyM51095 parC; topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D SpyM51097 parE; topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D SpyM51810 gidA; glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D SpyM51577 gidB; methyltransferase GidB K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D SpyM50904 protein Gid homolog K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]
D SpyM51116 engB; putative GTP-binding protein K03978 engB; GTP-binding protein
D SpyM51323 conserved hypothetical protein K09762 whiA; cell division protein WhiA
C 03400 DNA repair and recombination proteins [BR:spf03400]
D SpyM50616 phr; putative deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D SpyM51100 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
D SpyM50293 putative A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D SpyM51077 nth; putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D SpyM51020 mutX; mutator MutX protein (7,8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SpyM50611 Mut/NUDIX family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SpyM50178 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SpyM51760 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
D SpyM51461 fpg; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D SpyM51520 exoA; exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D SpyM51080 putative single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D SpyM51235 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D SpyM50152 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D SpyM50300 uvrA; UvrABC system protein A (UvrA protein) K03701 uvrA; excinuclease ABC subunit A
D SpyM50790 uvrB; UvrABC system protein B (UvrB protein) K03702 uvrB; excinuclease ABC subunit B
D SpyM50978 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
D SpyM50823 pcrA; putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D SpyM50081 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D SpyM50082 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D SpyM50069 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D SpyM50243 rpoE; putative DNA-directed RNA polymerase, delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
D SpyM50451 rpoZ; DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D SpyM50006 trcF; putative transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D SpyM51780 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D SpyM50289 mutS2; putative DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2
D SpyM51763 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D SpyM50620 xseA; putative exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D SpyM50621 xseB; putative exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D SpyM50811 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D SpyM51644 polC; DNA polymerase III PolC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
D SpyM50002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D SpyM50713 putative DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D SpyM51527 holB; putative DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D SpyM50268 putative exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D SpyM50748 dnaH; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D SpyM50296 ssb; single strand binding protein (SSB) K03111 ssb; single-strand DNA-binding protein
D SpyM50099 putative single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SpyM50284 hypothetical protein K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
D SpyM51758 recA; RecA recombinase (recombinase A) K03553 recA; recombination protein RecA
D SpyM51761 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D SpyM50035 ruvB; Holliday junction DNA helicase, subunit B K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D SpyM50489 putative phage endodeoxyribonuclease K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
D SpyM50452 priA; putative primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D SpyM50179 sms; putative DNA repair protein K04485 radA; DNA repair protein RadA/Sms
D SpyM51828 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
D SpyM50326 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D SpyM50017 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
D SpyM50701 recR; recombination protein RecR K06187 recR; recombination protein RecR
D SpyM50625 recN; putative DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D SpyM50437 recU; putative recombination protein U K03700 recU; recombination protein U
D SpyM51212 addA; putative ATP-dependent exonuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
D SpyM51213 addB; putative ATP-dependent exonuclease subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D SpyM51459 conserved hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
D SpyM50916 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D SpyM51251 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D SpyM50905 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D SpyM50630 hlpA; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SpyM51307 putative phage RecT family protein K07455 recT; recombination protein RecT
D SpyM50282 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D SpyM50884 putative phage repressor-like protein K01356 lexA; repressor LexA [EC:3.4.21.88]
D SpyM50470 RecX family protein K03565 recX; regulatory protein
D SpyM51328 putative ATP-dependent DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D SpyM50737 putative ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SpyM51512 nrdE; ribonucleoside-diphosphate reductase alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SpyM51514 nrdF; ribonucleoside-diphosphate reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D SpyM50735 putative ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D SpyM51257 conserved hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
C 03029 Mitochondrial biogenesis [BR:spf03029]
D SpyM50382 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D SpyM51188 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D SpyM51740 tsf; elongation factor Ts K02357 tsf; elongation factor Ts
D SpyM51355 tufA; elongation factor Tu (EF-Tu) K02358 tuf; elongation factor Tu
D SpyM50211 fus; elongation factor G (EF-G) K02355 fusA; elongation factor G
D SpyM51478 era; GTP-binding protein Era homolog K03595 era; GTPase
D SpyM50079 tyrS; putative tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D SpyM50141 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D SpyM51788 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D SpyM51783 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D SpyM50338 gatA; glutamyl-tRNA amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D SpyM50339 gatB; glutamyl-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D SpyM50337 gatC; glutamyl-tRNA amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D SpyM50296 ssb; single strand binding protein (SSB) K03111 ssb; single-strand DNA-binding protein
D SpyM50099 putative single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SpyM50347 dnaK; chaperone protein DnaK (heat shock protein 70) K04043 dnaK; molecular chaperone DnaK
D SpyM50346 grpE; GrpE protein (HSP-70 cofactor) K03687 GRPE; molecular chaperone GrpE
D SpyM51721 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D SpyM51722 groES; 10 kDa chaperonin K04078 groES; chaperonin GroES
D SpyM50348 dnaJ; chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D SpyM51177 putative cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SpyM50944 putative cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SpyM51561 membrane protein OxaA 2 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
D SpyM50188 membrane protein OxaA 1 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:spf02000]
D SpyM50175 ABC transporter ATP-binding membrane protein K18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump
D SpyM50176 ABC transporter ATP-binding membrane protein K18892 patB; ATP-binding cassette, subfamily B, multidrug efflux pump
D SpyM50920 ABC transporter ATP-binding membrane protein K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump
D SpyM50919 ABC transporter ATP-binding membrane protein K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump
D SpyM50321 ABC transporter ATP-binding membrane protein K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial
D SpyM50322 ABC transporter ATP-binding membrane protein K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial
D SpyM51133 ABC transporter ATP-binding protein K15738 uup; ABC transport system ATP-binding/permease protein
D SpyM50980 extracellular solute-binding protein K02012 afuA; iron(III) transport system substrate-binding protein
D SpyM50959 potD; spermidine/putrescine extracellular binding protein K11069 potD; spermidine/putrescine transport system substrate-binding protein
D SpyM50960 potC; spermidine/putrescine ABC transporter permease protein K11070 potC; spermidine/putrescine transport system permease protein
D SpyM50961 potB; putative spermidine/putrescine ABC transporter permease protein K11071 potB; spermidine/putrescine transport system permease protein
D SpyM50962 potA; putative spermidine/putrescine ABC transporter ATP-binding protein K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11]
D SpyM50151 putative glycine-betaine binding permease protein K02001 proW; glycine betaine/proline transport system permease protein
D SpyM50150 putative glycine betaine transport ATP-binding protein K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9]
D SpyM50934 ABC-type glycine betaine transport system protein K05845 opuC; osmoprotectant transport system substrate-binding protein
D SpyM50935 ABC-type glycine betaine transport system ATP-binding protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]
D SpyM51653 msmK; multiple sugar-binding transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D SpyM50802 malX; putative maltose/maltodextrin-binding protein precursor K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein
D SpyM50801 malC; putative maltose/maltodextrin ABC transport system permease protein K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D SpyM50800 malD; putative maltose/maltodextrin ABC transport system permease protein K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D SpyM50547 extracellular solute-binding protein K17318 lplA; putative aldouronate transport system substrate-binding protein
D SpyM50545 binding-protein-dependent transport system membrane protein K17319 lplB; putative aldouronate transport system permease protein
D SpyM50546 binding-protein-dependent transport system membrane protein K17320 lplC; putative aldouronate transport system permease protein
D SpyM50132 basic lipoprotein K07335 bmpA; basic membrane protein A and related proteins
D SpyM50856 putative lipoprotein K07335 bmpA; basic membrane protein A and related proteins
D SpyM50858 ABC transporter permease protein K23535 nupB; general nucleoside transport system permease protein
D SpyM50859 ABC transporter permease protein K23536 nupC; general nucleoside transport system permease protein
D SpyM50857 ABC transporter ATP-binding protein K23537 nupA; general nucleoside transport system ATP-binding protein
D SpyM50192 extracellular solute-binding lipoprotein K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein
D SpyM50193 putative transport system permease K02025 ABC.MS.P; multiple sugar transport system permease protein
D SpyM50194 putative transport system permease K02026 ABC.MS.P1; multiple sugar transport system permease protein
D SpyM50843 pstS; putative phosphate ABC transporter,extracellular phosphate-binding lipoprotein K02040 pstS; phosphate transport system substrate-binding protein
D SpyM50844 pstC; putative phosphate ABC transporter permease protein K02037 pstC; phosphate transport system permease protein
D SpyM50845 putative phosphate ABC transporter permease protein K02038 pstA; phosphate transport system permease protein
D SpyM50847 pstB1; phosphate import ATP-binding protein 1 K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D SpyM50846 pstB2; phosphate import ATP-binding protein 2 K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D SpyM50789 putative glutamine ABC transporter,glutamine-binding protein/permease protein K10036 glnH; glutamine transport system substrate-binding protein
D SpyM50788 glnQ1; putative glutamine ABC transporter, ATP-binding protein 1 K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1]
D SpyM51102 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein
D SpyM51585 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein
D SpyM51101 transport system membrane protein K10009 tcyB; L-cystine transport system permease protein
D SpyM50428 ABC transporter permease protein K10009 tcyB; L-cystine transport system permease protein
D SpyM50429 ABC transporter ATP-binding protein K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1]
D SpyM51211 extracellular solute-binding protein K23059 artP; arginine/lysine/histidine transporter system substrate-binding protein
D SpyM50614 putative amino acid ABC transporter permease protein K17077 artQ; arginine/lysine/histidine transport system permease protein
D SpyM50615 glnQ3; putative glutamine transporter, ATP-binding protein 3 K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1]
D SpyM51584 putative lipoprotein K02073 metQ; D-methionine transport system substrate-binding protein
D SpyM51582 putative D-methionine transport system permease protein K02072 metI; D-methionine transport system permease protein
D SpyM51583 putative D-methionine transport system ATP-binding protein K02071 metN; D-methionine transport system ATP-binding protein
D SpyM51016 putative exported protein K01989 K01989; putative tryptophan/tyrosine transport system substrate-binding protein
D SpyM51014 ABC transporter permease protein K05832 K05832; putative tryptophan/tyrosine transport system permease protein
D SpyM51013 ABC transporter ATP-binding protein K05833 K05833; putative tryptophan/tyrosine transport system ATP-binding protein
D SpyM50215 glutamine ABC transporter, glutamine-binding protein/permease protein K17073 lysX1; putative lysine transport system substrate-binding protein
D SpyM50214 glnQ2; putative glutamine ABC transporter, ATP-binding protein 2 K17076 lysY; putative lysine transport system ATP-binding protein
D SpyM50819 putative amino acid ABC transporter,extracellular amino acid-binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D SpyM50817 putative amino acid ABC transporter permease protein K02029 ABC.PA.P; polar amino acid transport system permease protein
D SpyM50818 putative amino acid ABC transporter ATP-binding protein K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1]
D SpyM50227 putative extracellular oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D SpyM50228 putative oligopeptide transporter permease protein K15581 oppB; oligopeptide transport system permease protein
D SpyM50229 putative oligopeptide transporter permease protein K15582 oppC; oligopeptide transport system permease protein
D SpyM50230 putative oligopeptide transporter ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein
D SpyM50231 putative oligopeptide transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein
D SpyM51673 dppA; dipeptide-binding extracellular protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SpyM51674 dppB; dipeptide transport system permease protein DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SpyM51675 dppC; dipeptide transport system permease protein DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SpyM51676 dppD; dipeptide transport system ATP-binding protein DppD K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SpyM51677 dppE; dipeptide transport system ATP-binding protein DppF K02032 ddpF; peptide/nickel transport system ATP-binding protein
D SpyM51535 fhuD; putative ferrichrome-binding protein precursor K25308 fhuD; ferric hydroxamate/heme transport system substrate-binding protein
D SpyM51536 fhuB; ferrichrome transport permease K25288 fhuB; ferric hydroxamate/heme transport system permease protein
D SpyM51537 fhuG; ferrichrome transport permease K25289 fhuG; ferric hydroxamate/heme transport system permease protein
D SpyM51534 fhuC; ferrichrome transport ATP-binding protein K25290 fhuA; ferric hydroxamate/heme transport system ATP-binding protein [EC:7.2.2.16]
D SpyM50318 putative transport system extracellular binding lipoprotein K25113 htsA; heme transport system substrate-binding protein
D SpyM50319 putative iron/heme permease K25114 htsB; heme transport system permease protein
D SpyM50320 ABC transporter ATP-binding protein K25115 htsC; heme transport system ATP-binding protein [EC:7.6.2.5]
D SpyM50317 putative membrane protein K25119 shp; heme transport system cell surface heme-binding protein
D SpyM50316 putative iron transport-associated protein K25120 shr; heme sequestration protein
D SpyM51680 lmb; laminin binding protein K09815 znuA; zinc transport system substrate-binding protein
D SpyM51261 adcA; zinc-binding protein AdcA precursor K09815 znuA; zinc transport system substrate-binding protein
D SpyM50077 ABC transporter permease protein K09816 znuB; zinc transport system permease protein
D SpyM50076 ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D SpyM51497 mtsA; metal ABC transporter substrate-binding lipoprotein precursor K11704 mtsA; iron/zinc/manganese/copper transport system substrate-binding protein
D SpyM51495 mtsC; metal cation ABC transporter membrane protein K11705 mtsC; iron/zinc/manganese/copper transport system permease protein
D SpyM51496 mtsB; metal cation ABC transporter ATP-binding protein K11706 mtsB; iron/zinc/manganese/copper transport system ATP-binding protein
D SpyM50159 BioY family protein K03523 bioY; biotin transport system substrate-specific component
D SpyM50323 putative membrane protein K16926 htsT; energy-coupling factor transport system substrate-specific component
D SpyM51362 putative membrane protein K16927 cbrT; energy-coupling factor transport system substrate-specific component
D SpyM51816 putative cobalt transport protein K16785 ecfT; energy-coupling factor transport system permease protein
D SpyM50324 putative membrane protein K16785 ecfT; energy-coupling factor transport system permease protein
D SpyM51818 ABC transporter ATP-binding protein K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D SpyM51817 ABC transporter ATP-binding protein K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D SpyM50325 ABC transporter ATP-binding protein K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D SpyM51239 sagI; ABC-2 type transporter protein K25142 lnrN; linearmycin/streptolysin S transport system permease protein
D SpyM51240 sagH; ABC-2 type transporter protein K25143 lnrM; linearmycin/streptolysin S transport system permease protein
D SpyM51241 sagG; ABC transporter ATP-binding protein K25144 lnrL; linearmycin/streptolysin S transport system ATP-binding protein
D SpyM51161 putative permease K24948 yknZ; antimicrobial peptide resistance transport system permease protein
D SpyM51689 putative permease protein K24948 yknZ; antimicrobial peptide resistance transport system permease protein
D SpyM51690 ABC transporter ATP-binding protein K24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-]
D SpyM51162 ABC transporter ATP-binding protein K24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-]
D SpyM51331 ftsX; putative cell division protein K09811 ftsX; cell division transport system permease protein
D SpyM51332 ftsE; putative cell division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein
D SpyM51440 putative membrane protein K25154 evrC; viologen exporter family transport system permease protein
D SpyM51441 putative membrane protein K25155 evrB; viologen exporter family transport system permease protein
D SpyM51442 ABC transporter ATP-binding protein K25156 evrA; viologen exporter family transport system ATP-binding protein
D SpyM50375 ABC transporter protein EcsB K25157 ecsB; ABC-2 type transport system permease protein
D SpyM50374 ABC transporter ATP-binding protein K25158 ecsA; ABC-2 type transport system ATP-binding protein
D SpyM50328 putative membrane protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D SpyM51201 putative polysaccharide export ABC transporter permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D SpyM50418 putative membrane protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D SpyM50809 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SpyM50417 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SpyM51200 putative polysaccharide export system ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SpyM50327 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SpyM51603 salY; putative salivaricin A transporter permease protein K02004 ABC.CD.P; putative ABC transport system permease protein
D SpyM51216 putative permease K02004 ABC.CD.P; putative ABC transport system permease protein
D SpyM50833 ABC transporter permease protein K02004 ABC.CD.P; putative ABC transport system permease protein
D SpyM51604 salX; putative salivaricin A transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D SpyM50832 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D SpyM51215 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D SpyM50220 sufC; putative ABC transporter, ATP-binding protein K09013 sufC; Fe-S cluster assembly ATP-binding protein
D SpyM50041 multi antimicrobial extrusion (MATE) family transporter K26937 dinF; MATE family, multidrug efflux pump
D SpyM50723 major facilitator superfamily protein K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter
D SpyM51504 putative glycerol-3-phosphate transporter K02445 glpT; MFS transporter, OPA family, glycerol-3-phosphate transporter
D SpyM51458 pmrA; multi-drug resistance efflux pump K08161 mdtG; MFS transporter, DHA1 family, multidrug resistance protein
D SpyM51762 lmrP; putative transporter protein K08152 lmrP; MFS transporter, DHA1 family, multidrug resistance protein B
D SpyM51387 major facilitator superfamily protein K18926 lmrB; MFS transporter, DHA2 family, lincomycin resistance protein
D SpyM50740 pstI; phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
D SpyM50739 ptsH; histidine-containing phosphocarrier protein (HPr) K02784 ptsH; phosphocarrier protein HPr
D SpyM51662 putative glucose-specific phosphotransferase system (PTS), IIABC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208]
D SpyM50308 scrA; putative sucrose-specific phosphotransferase system (PTS), IIABC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211]
D SpyM51385 beta-glucoside-specific phosphotransferase system (PTS), IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-]
D SpyM51743 sugar phosphotransferase system (PTS), IIABC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201]
D SpyM51146 fruA; putative fructose-specific phosphotransferase system (PTS), IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202]
D SpyM51609 lacF; putative lactose-specific phosphotransferase system (PTS), IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207]
D SpyM51608 lacE; putative lactose-specific phosphotransferase system (PTS), IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207]
D SpyM50784 putative lactose/cellobiose-specific phosphotransferase system (PTS), IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D SpyM51709 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D SpyM50783 putative lactose/cellobiose-specific phosphotransferase system (PTS), IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]
D SpyM51708 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]
D SpyM51707 sugar phosphotransferase system (PTS), IIC component K02761 celB; cellobiose PTS system EIIC component
D SpyM50786 sugar phosphotransferase system (PTS), IIC component K02761 celB; cellobiose PTS system EIIC component
D SpyM50389 sugar phosphotransferase system (PTS), IIA component K20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204]
D SpyM50390 sugar phosphotransferase system (PTS), IIB component K20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204]
D SpyM50391 sugar phosphotransferase system (PTS),galactitol-specific family, IIC component K20114 gatC; galactose PTS system EIIC component
D SpyM50366 manL; putative mannose-specific phosphotransferase system (PTS), IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191]
D SpyM50986 sugar phosphotransferase system (PTS),mannose/fructose family, IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D SpyM50365 manM; putative mannose-specific phosphotransferase system (PTS), IIC component K02795 manY; mannose PTS system EIIC component
D SpyM50984 sugar phosphotransferase system (PTS),mannose/fructose family, IIC component K02795 manY; mannose PTS system EIIC component
D SpyM50364 manN; putative mannose-specific phosphotransferase system (PTS), IID component K02796 manZ; mannose PTS system EIID component
D SpyM50983 sugar phosphotransferase system (PTS),mannose/fructose family, IID component K02796 manZ; mannose PTS system EIID component
D SpyM50985 sugar phosphotransferase system (PTS),mannose/fructose family, IIB component K19507 gfrB; fructoselysine/glucoselysine PTS system EIIB component [EC:2.7.1.-]
D SpyM51340 putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-]
D SpyM51342 agaV; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-]
D SpyM51343 agaW; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component
D SpyM51344 agaD; putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component
D SpyM50144 sugar phosphotransferase system (PTS), IIA component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]
D SpyM51637 putative PTS multi-domain regulator K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]
D SpyM50143 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D SpyM51636 sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D SpyM51635 putative sugar-specific permease K03475 ulaA; ascorbate PTS system EIIC component
D SpyM50142 putative sugar-specific permease, SgaT/UlaA family K03475 ulaA; ascorbate PTS system EIIC component
D SpyM51435 sugar phosphotransferase system (PTS), fructose family, IIA component K05881 dhaM; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaM [EC:2.7.1.121]
D SpyM50411 glpF1; glycerol uptake facilitator protein 1 K02440 glpF; glycerol uptake facilitator
D SpyM51434 glpF2; glycerol uptake facilitator protein 2 K02440 glpF; glycerol uptake facilitator
D SpyM50277 gla; glycerol facilitator-aquaporin K02440 glpF; glycerol uptake facilitator
D SpyM51088 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SpyM50699 putative formate/nitrite transporter family protein K21993 fdhC; formate transporter
D SpyM51209 mscL; large-conductance mechanosensitive channel K03282 mscL; large conductance mechanosensitive channel
D SpyM50241 mechanosensitive ion channel protein K22044 ybiO; moderate conductance mechanosensitive channel
D SpyM50299 CorA-like Mg2+ transporter protein K03284 corA; magnesium transporter
D SpyM51541 putative transport protein K03699 tlyC; magnesium and cobalt exporter, CNNM family
D SpyM51034 putative phage minor tail protein K21449 ata; trimeric autotransporter adhesin
D SpyM51155 cation efflux family protein K16264 czcD; cobalt-zinc-cadmium efflux system protein
D SpyM51829 putative sugar uptake protein K05340 glcU; glucose uptake protein
D SpyM51580 sodium:dicarboxylate symporter family protein K07862 sstT; serine/threonine transporter
D SpyM51578 cation transport protein K03498 trkH; trk/ktr system potassium uptake protein
D SpyM51579 TrkA family transport protein K03499 trkA; trk/ktr system potassium uptake protein
D SpyM51167 pyrP; uracil permease K02824 uraA; uracil permease
D SpyM50931 pbuX; putative xanthine permease K16169 pbuX; xanthine permease
D SpyM50368 putative permease K06901 pbuG; adenine/guanine/hypoxanthine permease
D SpyM50952 voltage gated chloride channel family protein K03281 clcA; chloride channel protein, CIC family
D SpyM50734 voltage gated chloride channel K03281 clcA; chloride channel protein, CIC family
D SpyM51254 voltage gated chloride channel protein K03281 clcA; chloride channel protein, CIC family
D SpyM50401 putative Na+/Pi-cotransporter protein K03324 yjbB; phosphate:Na+ symporter
D SpyM50707 probable potassium transport system protein K03549 kup; KUP system potassium uptake protein
D SpyM51545 putative membrane protein K23675 fmnP; riboflavin transporter
D SpyM51364 putative membrane protein K16789 thiT; thiamine transporter
D SpyM50698 putative membrane protein K16788 niaX; niacin transporter
D SpyM51357 ftsW; putative cell division protein K03588 ftsW; cell division protein FtsW
D SpyM50900 putative glutaconyl-CoA decarboxylase beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
D SpyM50894 putative Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
D SpyM50888 putative carboxylase subunit K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]
D SpyM50903 putative carboxylase subunit K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]
D SpyM50902 putative membrane protein K01573 oadG; oxaloacetate decarboxylase (Na+ extruding) subunit gamma
D SpyM50901 putative glutaconyl-CoA decarboxylase gamma subunit K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
D SpyM50895 putative decarboxylase gamma chain K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
D SpyM50568 putative cytochrome c-type biogenesis protein K06196 ccdA; cytochrome c-type biogenesis protein
D SpyM51691 putative exported protein K24950 yknX; membrane fusion protein, antimicrobial resistance system
D SpyM51163 putative exported protein K24950 yknX; membrane fusion protein, antimicrobial resistance system
D SpyM50779 nicotinamide mononucleotide transporter K03811 pnuC; nicotinamide mononucleotide transporter
C 02044 Secretion system [BR:spf02044]
D SpyM50606 putative membrane protein K02221 yggT; YggT family protein
D SpyM50711 comEA; putative competence protein K02237 comEA; competence protein ComEA
D SpyM50302 putative cytidine and deoxycytidylate deaminase K01493 comEB; dCMP deaminase [EC:3.5.4.12]
D SpyM50712 comEC; putative competence protein K02238 comEC; competence protein ComEC
D SpyM50464 comFA; putative late competence protein K02240 comFA; competence protein ComFA
D SpyM50465 comFC; putative late competence protein K02242 comFC; competence protein ComFC
D SpyM50084 putative competence protein K02243 comGA; competence protein ComGA
D SpyM50085 putative competence protein K02244 comGB; competence protein ComGB
D SpyM50086 comYC; putative competence protein K02245 comGC; competence protein ComGC
D SpyM50087 putative competence protein K02246 comGD; competence protein ComGD
D SpyM50089 putative membrane protein K02248 comGF; competence protein ComGF
D SpyM50592 type IV leader peptidase family protein K02236 comC; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
D SpyM50312 secA; putative preprotein SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D SpyM51713 putative preprotein translocase SecE subunit K03073 secE; preprotein translocase subunit SecE
D SpyM51457 secG; putative protein-export membrane protein K03075 secG; preprotein translocase subunit SecG
D SpyM50064 secY; preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY
D SpyM50883 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D SpyM51388 ftsY; putative cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor
D SpyM51649 putative preprotein translocase subunit K03210 yajC; preprotein translocase subunit YajC
D SpyM51561 membrane protein OxaA 2 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
D SpyM50188 membrane protein OxaA 1 precursor K03217 yidC; YidC/Oxa1 family membrane protein insertase
C 02042 Bacterial toxins [BR:spf02042]
D SpyM51511 putative mono-ADP-ribosyltransferase K11044 spyA; C3 family ADP-ribosyltransferase [EC:2.4.2.-]
D SpyM51087 C4-dicarboxylate transporter/malic acid transport protein K11041 eta; exfoliative toxin A/B
D SpyM50136 slo; streptolysin O precursor (thiol-activated cytolysin) K11031 slo; thiol-activated cytolysin
D SpyM51541 putative transport protein K03699 tlyC; magnesium and cobalt exporter, CNNM family
D SpyM50820 cfa; CAMP factor K11045 cfa; cAMP factor
D SpyM51247 Streptolysin S precursor K11046 sagA; streptolysin S associated protein
D SpyM50910 haemolysin-III related membrane protein K11068 hlyIII; hemolysin III
D SpyM51021 speH; streptococcal exotoxin H precursor K11040 se; staphylococcal enterotoxin
D SpyM51672 smeZ; mitogenic exotoxin Z precursor K11040 se; staphylococcal enterotoxin
D SpyM51264 speC; exotoxin C precursor K11040 se; staphylococcal enterotoxin
D SpyM50680 phage hyaluronoglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
D SpyM50524 putative phage hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
D SpyM50541 beta-N-acetylglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
D SpyM51271 putative phage hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
C 02022 Two-component system [BR:spf02022]
D SpyM51428 vicK; sensor histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
D SpyM51429 vicR; response regulator protein K07668 vicR; two-component system, OmpR family, response regulator VicR
D SpyM50851 ciaH; sensor histidine kinase K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
D SpyM50850 ciaR; response regulator protein K14983 ciaR; two-component system, OmpR family, response regulator CiaR
D SpyM51572 csrS; sensor histidine kinase K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]
D SpyM51573 csrR; response regulator protein K18941 arlR; two-component system, OmpR family, response regulator ArlR
D SpyM51687 sensor histidine kinase K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3]
D SpyM51688 response regulator protein K18987 irr; two-component system, OmpR family, response regulator Irr
D SpyM50458 sensor histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
D SpyM50459 response regulator protein K11618 liaR; two-component system, NarL family, response regulator LiaR
D SpyM51602 salK; sensor histidine kinase K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK
D SpyM51601 salR; response regulator protein K14989 salR; two-component system, NarL family, secretion system response regulator SalR
D SpyM50957 putative sensor kinase K02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3]
D SpyM50958 response regulator protein K02475 K02475; two-component system, CitB family, response regulator
D SpyM50537 putative sensor kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D SpyM50183 fasB; sensor histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
D SpyM50186 fasA; response regulator protein K07707 agrA; two-component system, LytTR family, response regulator AgrA
D SpyM50549 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
D SpyM50572 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
D SpyM50981 response regulator protein K07720 yesN; two-component system, response regulator YesN
D SpyM50550 response regulator protein K07720 yesN; two-component system, response regulator YesN
C 02035 Bacterial motility proteins [BR:spf02035]
D SpyM51102 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein
D SpyM51585 extracellular solute-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:spf04812]
D SpyM50603 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D SpyM50602 ftsA; putative cell division protein K03590 ftsA; cell division protein FtsA
D SpyM51838 putative chromosome partitioning protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
C 04147 Exosome [BR:spf04147]
D SpyM51248 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D SpyM50212 plr; glyceraldehyde-3-phosphate dehydrogenase,plasmin receptor K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D SpyM50252 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D SpyM50813 pyk; putative pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D SpyM51494 putative cyclophilin type peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D SpyM51721 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D SpyM50347 dnaK; chaperone protein DnaK (heat shock protein 70) K04043 dnaK; molecular chaperone DnaK
D SpyM50167 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D SpyM51830 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D SpyM51355 tufA; elongation factor Tu (EF-Tu) K02358 tuf; elongation factor Tu
D SpyM50373 HIT-family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D SpyM50917 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D SpyM51431 hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SpyM50114 atoB1; acetyl-CoA acetyltransferase 1 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM51432 putative thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM50447 atoB2; acetyl-CoA acetyltransferase 2 K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SpyM50065 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D SpyM51079 apt; adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D SpyM50409 glpK; glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30]
D SpyM50255 glnA; putative glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SpyM51004 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SpyM51354 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D SpyM50696 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
C 02048 Prokaryotic defense system [BR:spf02048]
D SpyM51597 type I restriction-modification system R protein K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D SpyM51598 type I restriction-modification system S protein K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D SpyM51599 type I restriction-modification system M protein K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D SpyM50091 conserved hypothetical protein K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]
D SpyM50653 phage DNA methylase K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]
D SpyM51290 putative phage HNH endonuclease K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]
D SpyM50474 hypothetical phage protein K07171 mazF; mRNA interferase MazF [EC:3.1.-.-]
D SpyM51407 putative plasmid stabilization system antitoxin protein K07473 dinJ; DNA-damage-inducible protein J
D SpyM51406 putative plasmid stabilization system protein K19092 parE1_3_4; toxin ParE1/3/4
D SpyM50603 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D SpyM51095 parC; topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D SpyM51097 parE; topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D SpyM51177 putative cysteine desulfhydrase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SpyM50944 putative cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels [BR:spf04040]
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules [BR:spf04090]
C 01504 Antimicrobial resistance genes [BR:spf01504]
D SpyM50343 putative D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
D SpyM50792 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
D SpyM50793 dltB; putative activated D-alanine transport protein K03739 dltB; membrane protein involved in D-alanine export
D SpyM50794 dltC; D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
D SpyM50795 dltD; putative D-alanyl-lipoteichoic acid biosynthesis protein K03740 dltD; D-alanine transfer protein
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins [BR:spf00536]
D SpyM50680 phage hyaluronoglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
D SpyM50524 putative phage hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
D SpyM50541 beta-N-acetylglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
D SpyM51271 putative phage hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:spf00537]
D SpyM50680 phage hyaluronoglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
D SpyM50524 putative phage hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
D SpyM50541 beta-N-acetylglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
D SpyM51271 putative phage hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
D SpyM50134 nga; nicotine adenine dinucleotide glycohydrolase precursor K18153 nga; NAD+ glycohydrolase [EC:3.2.2.5]
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:spf03100]
D tRNA-Ala-1 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D tRNA-Ala-2 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D tRNA-Ala-4 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D tRNA-Ala-3 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D tRNA-Ala-5 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D tRNA-Ala-6 tRNA-Ala_(TGC); tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D tRNA-Arg-7 tRNA-Arg_(TCT); tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D tRNA-Arg-1 tRNA-Arg_(ACG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D tRNA-Arg-3 tRNA-Arg_(ACG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D tRNA-Arg-4 tRNA-Arg_(CCG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D tRNA-Arg-5 tRNA-Arg_(CCT); tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D tRNA-Arg-6 tRNA-Arg_(ACG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D tRNA-Arg-2 tRNA-Arg_(ACG); tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D tRNA-Asn-1 tRNA-Asn_(GTT); tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D tRNA-Asn-2 tRNA-Asn_(GTT); tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D tRNA-Asn-3 tRNA-Asn_(GTT); tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D tRNA-Asp-2 tRNA-Asp_(GTC); tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D tRNA-Asp-3 tRNA-Asp_(GTC); tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D tRNA-Asp-1 tRNA-Asp_(GTC); tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D tRNA-Cys tRNA-Cys_(GCA); tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D tRNA-Gln-2 tRNA-Gln_(TTG); tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D tRNA-Gln-1 tRNA-Gln_(TTG); tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D tRNA-Glu-1 tRNA-Glu_(TTC); tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D tRNA-Glu-3 tRNA-Glu_(TTC); tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D tRNA-Glu-2 tRNA-Glu_(TTC); tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D tRNA-Gly-1 tRNA-Gly_(GCC); tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D tRNA-Gly-2 tRNA-Gly_(GCC); tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D tRNA-Gly-3 tRNA-Gly_(TCC); tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D tRNA-Gly-4 tRNA-Gly_(TCC); tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D tRNA-His tRNA-His_(GTG); tRNA-His K14226 tRNA-His; tRNA His
D tRNA-Ile-2 tRNA-Ile_(GAT); tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D tRNA-Ile-3 tRNA-Ile_(GAT); tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D tRNA-Ile-1 tRNA-Ile_(GAT); tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D tRNA-Leu-1 tRNA-Leu_(TAG); tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D tRNA-Leu-5 tRNA-Leu_(CAA); tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D tRNA-Leu-2 tRNA-Leu_(TAA); tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D tRNA-Leu-3 tRNA-Leu_(TAG); tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D tRNA-Leu-7 tRNA-Leu_(TAG); tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D tRNA-Leu-4 tRNA-Leu_(TAA); tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D tRNA-Leu-6 tRNA-Leu_(AAG); tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D tRNA-Lys-1 tRNA-Lys_(TTT); tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D tRNA-Lys-2 tRNA-Lys_(TTT); tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D tRNA-Lys-3 tRNA-Lys_(TTT); tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D tRNA-Lys-4 tRNA-Lys_(CTT); tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D tRNA-Met-1 tRNA-Met_(CAT); tRNA-Met K14230 tRNA-Met; tRNA Met
D tRNA-Met-2 tRNA-Met_(CAT); tRNA-Met K14230 tRNA-Met; tRNA Met
D tRNA-Met-3 tRNA-Met_(CAT); tRNA-Met K14230 tRNA-Met; tRNA Met
D tRNA-Phe-1 tRNA-Phe_(GAA); tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D tRNA-Phe-2 tRNA-Phe_(GAA); tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D tRNA-Pro-1 tRNA-Pro_(TGG); tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D tRNA-Pro-2 tRNA-Pro_(TGG); tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D tRNA-Ser-4 tRNA-Ser_(GGA); tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D tRNA-Ser-1 tRNA-Ser_(TGA); tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D tRNA-Ser-2 tRNA-Ser_(GCT); tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D tRNA-Ser-3 tRNA-Ser_(TGA); tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D tRNA-Thr-1 tRNA-Thr_(TGT); tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D tRNA-Thr-3 tRNA-Thr_(TGT); tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D tRNA-Thr-4 tRNA-Thr_(GGT); tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D tRNA-Thr-2 tRNA-Thr_(TGT); tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D tRNA-Trp tRNA-Trp_(CCA); tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D tRNA-Tyr-2 tRNA-Tyr_(GTA); tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D tRNA-Tyr-1 tRNA-Tyr_(GTA); tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D tRNA-Val-1 tRNA-Val_(TAC); tRNA-Val K14237 tRNA-Val; tRNA Val
D tRNA-Val-3 tRNA-Val_(TAC); tRNA-Val K14237 tRNA-Val; tRNA Val
D tRNA-Val-2 tRNA-Val_(TAC); tRNA-Val K14237 tRNA-Val; tRNA Val
D tRNA-Val-4 tRNA-Val_(TAC); tRNA-Val K14237 tRNA-Val; tRNA Val
D 16S_rRNA-1 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 16S_rRNA-3 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 16S_rRNA-6 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 16S_rRNA-2 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 16S_rRNA-4 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 16S_rRNA-5 16S_rRNA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D 23S_rRNA-2 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 23S_rRNA-1 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 23S_rRNA-3 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 23S_rRNA-4 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 23S_rRNA-5 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 23S_rRNA-6 23S_rRNA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D 5S_rRNA-1 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D 5S_rRNA-3 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D 5S_rRNA-2 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D 5S_rRNA-4 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D 5S_rRNA-5 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D 5S_rRNA-6 5S_rRNA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D ssrA ssrA; tmRNA (RF00023) as predicted by Rfam, score 139.25 K15035 ssrA; transfer-messenger RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D SpyM51339 idnO; putative gluconate 5-dehydrogenase K00046 idnO; gluconate 5-dehydrogenase [EC:1.1.1.69]
D SpyM51519 lctO; L-lactate oxidase K10530 lctO; L-lactate oxidase [EC:1.1.3.2]
D SpyM51727 ndh; NADH dehydrogenase K03387 ahpF; NADH-dependent peroxiredoxin subunit F [EC:1.8.1.-]
D SpyM51486 msrA; peptide methionine sulfoxide reductase K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D SpyM50570 msrAB; peptide methionine sulfoxide reductase K12267 msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12]
D SpyM50988 msrB; peptide methionine sulfoxide reductase K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]
D SpyM51726 ahpC; alkyl hydroperoxide reductase subunit C K24119 ahpC; NADH-dependent peroxiredoxin subunit C [EC:1.11.1.26]
D SpyM51151 pyridine nucleotide-disulphide oxidoreductase family protein K21567 fnr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1]
D SpyM51111 ArsC family protein K00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1]
D SpyM51748 nrdG; putative anaerobic ribonucleoside-triphosphate reductase activating protein K04068 nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4]
D SpyM51540 pflC; pyruvate formate-lyase activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D SpyM51712 putative pyruvate formate-lyase activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D SpyM50440 putative RNA methylase family protein K07444 ypsC; putative N6-adenine-specific DNA methylase [EC:2.1.1.-]
D SpyM51454 putative glutamine cyclotransferase K22757 QCT; glutaminyl-peptide cyclotransferase [EC:2.3.2.5]
D SpyM51417 glycosyltransferase K21349 ggs; glucosylglycerate synthase [EC:2.4.1.268]
D SpyM51376 lgt; prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]
D SpyM50930 ApbE family protein K03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180]
D SpyM50249 conserved hypothetical protein K07030 fakA; fatty acid kinase [EC:2.7.2.18]
D SpyM51055 putative phage DNA polymerase K02334 dpo; DNA polymerase bacteriophage-type [EC:2.7.7.7]
D SpyM50998 putative membrane protein K18672 dacA; diadenylate cyclase [EC:2.7.7.85]
D SpyM51377 ptsK; HPr kinase/phosphorylase K06023 hprK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-]
D SpyM51011 putative esterase K03930 estA; putative tributyrin esterase [EC:3.1.1.-]
D SpyM51594 conserved hypothetical protein K07015 yqeG; putative phosphatase [EC:3.1.3.-]
D SpyM51809 DHH family protein K22927 gdpP; cyclic-di-AMP phosphodiesterase [EC:3.1.4.59]
D SpyM50199 TatD related DNase K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D SpyM50200 conserved hypothetical protein K05985 rnmV; ribonuclease M5 [EC:3.1.26.8]
D SpyM51652 dexB; glucan 1,6-alpha-glucosidase K01215 dexB; glucan 1,6-alpha-glucosidase [EC:3.2.1.70]
D SpyM51341 ugl; putative unsaturated glucuronyl hydrolase K18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180]
D SpyM50225 putative D-alanyl-D-alanine carboxypeptidase K01286 E3.4.16.4; D-alanyl-D-alanine carboxypeptidase [EC:3.4.16.4]
D SpyM51131 fms; peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D SpyM51641 def; polypeptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D SpyM50742 polysaccharide deacetylase family protein K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104]
D SpyM50118 Endoribonuclease L-PSP family protein K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]
D SpyM51483 myosin-crossreactive antigen K10254 ohyA; oleate hydratase [EC:4.2.1.53]
D SpyM51347 cation transporting ATPase K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10]
D SpyM50693 putative cation-transporting ATPase K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]
C 99981 Carbohydrate metabolism
C 99982 Energy metabolism
D SpyM51190A putative ferredoxin K05337 fer; ferredoxin
D SpyM50223 iscU; NifU-like protein K04488 iscU; nitrogen fixation protein NifU and related proteins
C 99983 Lipid metabolism
D SpyM51135 DegV family protein K25232 fakB; fatty acid kinase fatty acid binding subunit
D SpyM50627 conserved hypothetical protein K25232 fakB; fatty acid kinase fatty acid binding subunit
C 99984 Nucleotide metabolism
D SpyM51513 nrdI; NrdI protein K03647 nrdI; protein involved in ribonucleotide reduction
D SpyM51660 putative NrdI-like protein K03647 nrdI; protein involved in ribonucleotide reduction
D SpyM51263 streptococcal phage DNAse K15051 endA; DNA-entry nuclease
D SpyM51702 sdbII; streptococcal phage-like DNAse K15051 endA; DNA-entry nuclease
D SpyM50534 streptococcal phage DNAse K15051 endA; DNA-entry nuclease
D SpyM50691 streptococcal phage DNAse K15051 endA; DNA-entry nuclease
C 99985 Amino acid metabolism
D SpyM50914 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein K08234 yaeR; glyoxylase I family protein
D SpyM50604 conserved hypothetical protein K06997 yggS; PLP dependent protein
C 99986 Glycan metabolism
C 99987 Cofactor metabolism
C 99988 Secondary metabolism
C 99999 Others
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D SpyM51725 csp; cold shock protein K03704 cspA; cold shock protein
D SpyM51316 putative phage antirepressor protein K07741 antB; anti-repressor protein
D SpyM50476 putative phage antirepressor protein K07741 antB; anti-repressor protein
D SpyM50839 spxA; regulatory protein Spx K16509 spxA; regulatory protein spx
D SpyM51757 regulatory protein Spx K16509 spxA; regulatory protein spx
D SpyM51380 putative transcription accessory protein K06959 tex; protein Tex
C 99974 Translation
D SpyM50461 putative S1 RNA binding domain protein K07570 GSP13; general stress protein 13
C 99975 Protein processing
D SpyM50242 tig; trigger factor (prolyl isomerase) K03545 tig; trigger factor
D SpyM51455 smpB; SsrA-binding protein K03664 smpB; SsrA-binding protein
D SpyM50738 nrdH; glutaredoxin-like protein K06191 nrdH; glutaredoxin-like protein NrdH
D SpyM50218 mecA; adapter protein MecA K16511 mecA1_2; adapter protein MecA 1/2
C 99976 Replication and repair
D SpyM50948 radC; DNA repair protein RadC K03630 radC; DNA repair protein RadC
D SpyM50205 RmuC family protein K09760 rmuC; DNA recombination protein RmuC
D SpyM50708 conserved hypothetical protein K07461 K07461; putative endonuclease
D SpyM50906 SMF family protein K04096 smf; DNA processing protein
D SpyM51078 putative DNA replication protein DnaD K02086 dnaD; DNA replication protein
D SpyM51311 putative phage DNA replication protein K02086 dnaD; DNA replication protein
D SpyM50641 hypothetical phage protein K02086 dnaD; DNA replication protein
D SpyM51049 putative phage terminase, small subunit K07474 xtmA; phage terminase small subunit
D SpyM51048 putative phage terminase, large subunit K06909 xtmB; phage terminase large subunit
D SpyM51669 putative ATPase K07478 ycaJ; putative ATPase
D SpyM51054 putative phage DNA primase/helicase protein K06919 K06919; putative DNA primase/helicase
D SpyM51774 putative phage replication protein K06919 K06919; putative DNA primase/helicase
D SpyM50071 insertion sequence IS1239 putative transposase K07482 K07482; transposase, IS30 family
D SpyM50164 insertion sequence IS1239 putative transposase K07482 K07482; transposase, IS30 family
D SpyM50798 putative transposase K07482 K07482; transposase, IS30 family
D SpyM50974 insertion sequence IS1239 putative transposase K07482 K07482; transposase, IS30 family
D SpyM50617 insertion sequence IS1239 putative transposase K07482 K07482; transposase, IS30 family
D SpyM50235 putative transposase K07483 K07483; transposase
D SpyM50775 insertion sequence IS861 putative transposase K07483 K07483; transposase
D SpyM50771 putative transposase K07483 K07483; transposase
D SpyM50733 putative transposase for IS element K07483 K07483; transposase
D SpyM51392 putative transposase K07483 K07483; transposase
D SpyM51393 putative transposase K07497 K07497; putative transposase
D SpyM50774 isertion sequence IS861 putative transposase K07497 K07497; putative transposase
C 99979 Viral proteins
C 99998 Others
D SpyM50270 conserved hypothetical protein K09747 ebfC; nucleoid-associated protein EbfC
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D SpyM50432 amino acid permease K03293 TC.AAT; amino acid transporter, AAT family
D SpyM50014 putative amino acid permease K03294 TC.APA; basic amino acid/polyamine antiporter, APA family
D SpyM50897 putative Mg2+/citrate complex transporter K03300 TC.CITMHS; citrate-Mg2+:H+ or citrate-Ca2+:H+ symporter, CitMHS family
D SpyM50822 sodium:alanine symporter family protein K03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family
D SpyM51581 putative branched-chain amino acid transport system carrier protein K03311 TC.LIVCS; branched-chain amino acid:cation transporter, LIVCS family
D SpyM50264 putative Na+ dependent nucleoside transporter K03317 TC.CNT; concentrative nucleoside transporter, CNT family
C 99978 Cell growth
D SpyM50441 putative membrane protein K20073 mapZ; mid-cell-anchored protein Z
D SpyM50189 putative ssDNA-binding protein K06346 jag; spoIIIJ-associated protein
D SpyM51322 putative phage integrase K06400 spoIVCA; site-specific DNA recombinase
C 99993 Cell motility
C 99995 Signaling proteins
D SpyM50597 BipA family GTPase K06207 typA; GTP-binding protein
D SpyM51482 PhoH-like protein K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins
C 99992 Structural proteins
D SpyM51363 glycosyl hydrolases family protein K07273 acm; lysozyme
C 99994 Others
D SpyM50848 phoU; putative phosphate transport system protein K02039 phoU; phosphate transport system protein
D SpyM51522 CutC family protein K06201 cutC; copper homeostasis protein
B
B 09194 Poorly characterized
C 99996 General function prediction only
D SpyM51750 putative oxidoreductase K03810 mviM; virulence factor
D SpyM50721 competence protein CoiA-like family protein K06198 coiA; competence protein CoiA
D SpyM50098 putative tRNA-binding protein K06878 K06878; tRNA-binding protein
D SpyM51367 haloacid dehalogenase-like hydrolase K07025 K07025; putative hydrolase of the HAD superfamily
D SpyM50224 sufB; conserved hypothetical protein K09014 sufB; Fe-S cluster assembly protein SufB
D SpyM50221 sufD; conserved hypothetical protein K09015 sufD; Fe-S cluster assembly protein SufD
D SpyM50757 ribonuclease BN-like family protein K07058 K07058; membrane protein
D SpyM51090 conserved hypothetical protein K07146 K07146; UPF0176 protein
D SpyM51576 LemA family protein K03744 lemA; LemA protein
D SpyM51803 putative membrane protein K01421 yhgE; putative membrane protein
D SpyM51799 putative membrane protein K08974 K08974; putative membrane protein
D SpyM51383 putative membrane protein K08986 ycgQ; putative membrane protein
D SpyM50816 PhnA protein K06193 phnA; protein PhnA
C 99997 Function unknown
D SpyM51349 putative phosphohydrolase K06885 K06885; uncharacterized protein
D SpyM50245 putative exported protein K06889 K06889; uncharacterized protein
D SpyM51557 putative membrane protein K06890 K06890; uncharacterized protein
D SpyM50153 putative CoA binding protein K06929 K06929; uncharacterized protein
D SpyM51558 conserved hypothetical protein K06950 K06950; uncharacterized protein
D SpyM51158 conserved hypothetical protein K06960 K06960; uncharacterized protein
D SpyM51624 conserved hypothetical protein K06962 K06962; uncharacterized protein
D SpyM51237 endonuclease/exonuclease/phosphatase family surface anchored protein K07004 K07004; uncharacterized protein
D SpyM51156 conserved hypothetical protein K07006 K07006; uncharacterized protein
D SpyM51150 putative membrane protein K07035 K07035; uncharacterized protein
D SpyM51214 putative neutral zinc metallopeptidase K07054 K07054; uncharacterized protein
D SpyM51382 putative permease K07089 K07089; uncharacterized protein
D SpyM51553 putative phosphoesterase K07095 K07095; uncharacterized protein
D SpyM50697 conserved hypothetical protein K07105 K07105; uncharacterized protein
D SpyM51081 short chain dehydrogenase K07124 K07124; uncharacterized protein
D SpyM51543 radical SAM superfamily protein K07139 K07139; uncharacterized protein
D SpyM51547 conserved hypothetical protein K08998 K08998; uncharacterized protein
D SpyM50539 conserved hypothetical protein K09704 K09704; uncharacterized protein
D SpyM50882 putative DNA-binding protein K09787 K09787; uncharacterized protein
D SpyM51487 conserved hypothetical protein K00243 K00243; uncharacterized protein
D SpyM51747 conserved hypothetical protein K09861 K09861; uncharacterized protein
D SpyM50781 conserved hypothetical protein K09963 K09963; uncharacterized protein
D SpyM51556 putative exported protein K09976 K09976; uncharacterized protein
D SpyM50679 hypothetical phage protein K01163 K01163; uncharacterized protein
D SpyM51173 conserved hypothetical protein K07584 ysxB; uncharacterized protein
D SpyM50469 conserved hypothetical protein K07586 ygaC; uncharacterized protein
D SpyM50380 conserved hypothetical protein K07742 ylxR; uncharacterized protein
!
#
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: May 22, 2024