+C Peptidases and inhibitors KO
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Peptidases and Inhibitors - Schizosaccharomyces pombe (fission yeast)
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AAspartic peptidases
B Family A1: pepsin family
B Family A2: retropepsin family
B Family A5: thermopsin family
B Family A8: signal peptidase II family
B Family A22: presenilin family
C SPAC25B8.17 peptidase family A22 K09595 HM13; minor histocompatibility antigen H13 [EC:3.4.23.-]
B Family A24: type IV prepilin peptidase family
B Family A25: gpr protease family
B Family A26: omptin family
B Family A28
B Family A31: HybD endopeptidase family
B Family A36
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ACysteine peptidases
B Family C1: papain family
B Family C2: calpain family
B Family C3: picornain family
B Family C4: NIa protease family
B Family C5
B Family C9
B Family C10: streptopain family
B Family C11: clostripain family
B Family C12: ubiquitin C-terminal hydrolase family
C SPAC27F1.03c uch1; ubiquitin hydrolase Uch1 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C SPBC409.06 uch2; ubiquitin hydrolase Uch2 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
B Family C13: legumain family
B Family C14: caspase family
C SPCC1840.04 pca1; metacaspase Pca1 K22684 MCA1; metacaspase-1 [EC:3.4.22.-]
B Family C15: pyroglutamyl peptidase I family
B Family C16
B Family C19: ubiquitin-specific protease family
C SPBC6B1.06c ubp14; ubiquitin hydrolase Ubp14 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
C SPCC16A11.12c ubp1; ubiquitin hydrolase Ubp1 K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
C SPCC1494.05c ubp12; CSN-associated deubiquitinating enzyme Ubp12 K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
C SPBC18H10.08c ubp4; ubiquitin hydrolase Ubp4 K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
C SPAC6G9.08 ubp6; ubiquitin hydrolase Ubp6 K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
C SPCC188.08c ubp5; ubiquitin hydrolase Ubp5 K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
C SPBC713.02c ubp15; ubiquitin hydrolase Ubp15 K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
C SPBP8B7.21 ubp3; ubiquitin hydrolase Ubp3 K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
C SPAC23G3.08c ubp7; ubiquitin hydrolase Ubp7 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
C SPAC13A11.04c ubp8; SAGA complex ubiquitin Ubp8 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
C SPAC328.06 ubp2; ubiquitin hydrolase Ubp2 K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
C SPCC1682.12c ubp16; ubiquitin hydrolase Ubp16 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
C SPBC1703.12 ubp9; ubiquitin hydrolase Ubp9 K11872 UBP9_13; ubiquitin carboxyl-terminal hydrolase 9/13 [EC:3.4.19.12]
B Family C25: gingipain family
B Family C26: gamma-glutamyl hydrolase family
C SPAP7G5.02c gua2; putative GMP synthase Gua2 K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
B Family C27
B Family C30
B Family C37
B Family C39
B Family C40
B Family C44
C SPAC4D7.08c ade4; amidophosphoribosyltransferase Ade4 K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C SPBC12C2.11 putative glutamine-fructose-6-phosphate transaminase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C SPBC119.10 asn1; asparagine synthetase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
B Family C45
B Family C46: hedgehog family
B Family C47: staphopain family
B Family C48: Ulp1 endopeptidase family
C SPBC19G7.09 ulp1; SUMO deconjugating enzyme Ulp1 K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C SPAC17A5.07c ulp2; putative SUMO deconjugating cysteine peptidase Ulp2 K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C SPBC17D11.01 nep1; NEDD8 protease Nep1 K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C SPBC32H8.02c nep2; NEDD8 protease Nep2 K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
B Family C50: separase family
C SPCC5E4.04 cut1; separase/separin K02365 ESP1; separase [EC:3.4.22.49]
B Family C54: Aut2 peptidase family
C SPAC19B12.08 atg4; putative Atg8 deconjugator Atg4 K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
B Family C55: YopJ protease family
B Family C56: PfpI endopeptidase family
B Family C57: vaccinia virus I7 peptidase family
B Family C58
B Family C59
B Family C60
B Family C63
B Family C64
B Family C65
B Family C67
B Family C69
B Family C70
B Family C75
B Family C76
B Family C78
B Family C79
B Family C82
B Family C83
C SPAC3H1.10 phytochelatin synthetase K05941 E2.3.2.15; glutathione gamma-glutamylcysteinyltransferase [EC:2.3.2.15]
B Family C85
B Family C86
B Family C88
C SPAC24C9.14 otu1; OUT family ubiquitin-specific cysteine protease Otu1 K13719 OTU1; ubiquitin thioesterase OTU1 [EC:3.1.2.-]
B Family C89
B Family C97
B Family C98
B Family C110
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AGlutamic peptidases
B Family G1
B Family G4
B Family G5: prenyl protease 2 family
C SPAC1687.02 putative CAAX prenyl protease K08658 RCE1; intramembrane prenyl-peptidase [EC:3.4.26.1]
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AMetallo peptidases
B Family M1
C SPCC1322.05c putative leukotriene A-4 hydrolase K01254 LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]
C SPBC1921.05 ape2; putative aminopeptidase Ape2 K13721 APE2; aminopeptidase 2 [EC:3.4.11.-]
C SPAC3A12.05c taf2; putative TATA-binding protein-associated factor Taf2 K03128 TAF2; transcription initiation factor TFIID subunit 2
B Family M2
B Family M3
C SPAC1F3.10c oct1; putative peptidase Oct1 K01410 MIPEP; mitochondrial intermediate peptidase [EC:3.4.24.59]
B Family M4: thermolysin family
B Family M5: mycolysin family
B Family M6: immune inhibitor A family
B Family M7: snapalysin family
B Family M8: leishmanolysin family
B Family M9
B Family M10
B Family M12: astacin/adamalysin family
B Family M13: neprilysin family
B Family M14: carboxypeptidase A family
C SPBC337.07c putative carboxypeptidase K08783 ECM14; extracellular matrix protein 14 [EC:3.4.17.-]
B Family M15: zinc D-Ala-D-Ala carboxypeptidase family
B Family M16: pitrilysin family
C SPACUNK4.12c mug138; putative metallopeptidase K01408 IDE; insulysin [EC:3.4.24.56]
C SPBC119.17 putative metalloendopeptidase K06972 PITRM1; presequence protease [EC:3.4.24.-]
C SPBC18E5.12c mas2; putative MPP complex alpha subunit Mas2 K01412 PMPCA; mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]
C SPBP23A10.15c qcr1; putative MPP complex beta subunit Qcr1 K17732 PMPCB; mitochondrial-processing peptidase subunit beta [EC:3.4.24.64]
C SPCC613.10 qcr2; putative ubiquinol-cytochrome-c reductase complex core protein Qcr2 K00415 QCR2; ubiquinol-cytochrome c reductase core subunit 2
B Family M17: leucyl aminopeptidase family
C SPAC13A11.05 peptidase family M17 K11142 LAP3; cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5]
B Family M18
C SPAC4F10.02 aap1; aspartyl aminopeptidase Aap1 K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
B Family M19: membrane dipeptidase family
C SPCC965.12 putative dipeptidyl peptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
C SPAC3A11.10c putative dipeptidyl peptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
B Family M20
C SPAC24C9.08 putative carboxypeptidase K01293 E3.4.17.4; Gly-Xaa carboxypeptidase [EC:3.4.17.4]
C SPBC1198.08 putative dipeptidase Dug1 K15428 DUG1; Cys-Gly metallodipeptidase DUG1 [EC:3.4.13.-]
B Family M23
B Family M24
C SPBC14C8.03 fma2; putative methionine aminopeptidase Fma2 K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C SPBC3E7.10 fma1; putative methionine aminopeptidase Fma1 K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C SPAC22G7.01c putative Fe-responsive transcriptional regulator K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
C SPAC12B10.05 icp55; putative peptidase Icp55 K18573 ICP55; intermediate cleaving peptidase 55 [EC:3.4.11.26]
B Family M26
B Family M27
B Family M28: aminopeptidase Y family
B Family M29: aminopeptidase T family
B Family M32: carboxypeptidase Taq family
B Family M34: anthrax lethal factor family
B Family M35: deuterolysin family
B Family M36: fungalysin family
B Family M38: beta-aspartyl dipeptidase family
B Family M41: FtsH endopeptidase family
C SPBC543.09 yta12; putative m-AAA protease Yta12 K08956 AFG3; AFG3 family protein [EC:3.4.24.-]
C SPCC965.04c putative i-AAA protease Yme1 K08955 YME1; ATP-dependent metalloprotease [EC:3.4.24.-]
B Family M42: glutamyl aminopeptidase family
B Family M43: cytophagalysin family
B Family M44
B Family M48: Ste24 endopeptidase family
C SPAC3H1.05 putative CAAX prenyl protease K06013 STE24; STE24 endopeptidase [EC:3.4.24.84]
C SPAP14E8.04 oma1; putative metallopeptidase Oma1 K23010 OMA1; metalloendopeptidase OMA1, mitochondrial [EC:3.4.24.-]
B Family M49: dipeptidyl-peptidase III family
B Family M50: S2P protease family
B Family M54
B Family M55: DppA aminopeptidase family
B Family M56
B Family M67
C SPAC31G5.13 rpn11; 19S proteasome regulatory subunit Rpn11 K03030 PSMD14; 26S proteasome regulatory subunit N11
C SPAC1687.13c csn5; COP9/signalosome complex subunit Csn5 K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
C SPAC19B12.10 sst2; AMSH-like ubiquitin-specific protease K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
B Family M72
B Family M73
B Family M74
B Family M80
B Family M82
B Family M85
B Family M88
B Family M90
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AAsparagine peptide lyases
B Family N1
B Family N8
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AMixed peptidases
B Family P1: DmpA aminopeptidase family
B Family P2
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ASerine peptidases
B Family S1: chymotrypsin family
C SPAC23G3.12c putative serine protease K22686 NMA111; pro-apoptotic serine protease NMA111 [EC:3.4.21.-]
B Family S3: togavirin family
B Family S6
B Family S7: flavivirin family
B Family S8: subtilisin family
C SPAC1006.01 psp3; putative serine protease Psp3 K01336 PRB1; cerevisin [EC:3.4.21.48 3.4.21.-]
C SPAC4A8.04 isp6; vacuolar serine protease Isp6 K01336 PRB1; cerevisin [EC:3.4.21.48 3.4.21.-]
C SPAC22E12.09c krp1; kexin K01341 KEX2; kexin [EC:3.4.21.61]
C SPAP8A3.12c tpp2; tripeptidyl-peptidase II Tpp2 K01280 TPP2; tripeptidyl-peptidase II [EC:3.4.14.10]
B Family S9: prolyl oligopeptidase family
C SPACUNK4.08 putative dipeptidyl peptidase K01282 DAP2; dipeptidyl aminopeptidase B [EC:3.4.14.-]
C SPBC32H8.03 bem46; putative esterase/lipase K24083 ABHD13; abhydrolase domain-containing protein 13 [EC:3.-.-.-]
B Family S10
C SPAC19G12.10c cpy1; vacuolar carboxypeptidase Y K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
C SPBC16G5.09 putative serine carboxypeptidase K01288 KEX1; carboxypeptidase D [EC:3.4.16.6]
C SPAC1296.03c sxa2; serine carboxypeptidase Sxa2 K01288 KEX1; carboxypeptidase D [EC:3.4.16.6]
B Family S11: D-Ala-D-Ala carboxypeptidase A family
B Family S12: D-Ala-D-Ala carboxypeptidase B family
B Family S13: D-Ala-D-Ala peptidase C family
B Family S14: ClpP endopeptidase family
B Family S15
B Family S16: lon protease family
C SPAC22F3.06c lon1; Lon protease K08675 PRSS15; ATP-dependent Lon protease [EC:3.4.21.53]
B Family S21: assemblin family
B Family S24: LexA family
B Family S26: signal peptidase I family
C SPBC1685.03 sec11; putative signal peptidase subunit Sec11 K13280 SEC11; signal peptidase I [EC:3.4.21.89]
C SPBC2D10.07c putative endopeptidase catalytic subunit K09647 IMP1; mitochondrial inner membrane protease subunit 1 [EC:3.4.21.-]
C SPBC336.13c putative endopeptidase catalytic subunit K09648 IMP2; mitochondrial inner membrane protease subunit 2 [EC:3.4.21.-]
B Family S28
B Family S31
B Family S32
B Family S33
C SPCC5E4.05c putative serine hydrolase K01054 MGLL; acylglycerol lipase [EC:3.1.1.23]
C SPBP4H10.17c putative carboxyl methyl esterase K13617 PPME1; protein phosphatase methylesterase 1 [EC:3.1.1.89]
B Family S41: C-terminal processing peptidase family
B Family S45
B Family S49: protease IV family
B Family S50
B Family S51
B Family S53
B Family S54: Rhomboid family
C SPBC13E7.11 putative rhomboid protease K09650 PARL; rhomboid-like protein [EC:3.4.21.105]
B Family S55: SpoIVB peptidase family
B Family S62
B Family S66
B Family S77: phage prohead processing peptidase family
B Family S78
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AThreonine peptidases
B Family T1: proteasome family
C SPBC646.16 putative proteasome core particle subunit alpha 1 K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
C SPCC1442.06 pre8; putative proteasome core particle subunit alpha 2 Pre8 K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
C SPAC13C5.01c putative proteasome core particle subunit alpha 3 K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
C SPBC106.16 pre6; 20S proteasome component alpha 4 Pre6 K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
C SPAC323.02c pup2; putative proteasome core particle subunit alpha 5 Pup2 K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
C SPAC6G10.04c putative proteasome core particle subunit alpha 6 Pre5 K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
C SPCC1795.04c pre10; putative proteasome core particle subunit alpha 7 Pre10 K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
C SPBC4C3.10c pre3; putative proteasome core particle subunit beta 1 Pre3 K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
C SPAC23D3.07 pup1; putative proteasome core particle subunit beta 2 K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
C SPCC63.12c pup3; putative proteasome core particle subunit beta 3 Pup3 K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
C SPAC31A2.04c putative proteasome core particle subunit beta 4 K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
C SPAC4A8.13c pts1; 20S proteasome component beta 5 K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
C SPAC22F8.06 pam1; 20S proteasome component beta 6 K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
C SPBC577.10 putative proteasome core particle subunit beta 7 K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
B Family T2
B Family T3: gamma-glutamyltransferase family
C SPAC664.09 ggt1; gamma-glutamyltranspeptidase Ggt1 K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
C SPAC56E4.06c ggt2; gamma-glutamyltranspeptidase Ggt2 K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
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APeptidases of unknown catalytic type
B Family U32
B Family U62
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APeptidase inhibitors
B Family I1: Kazal family
B Family I2: Kunitz - BPTI family
B Family I4: serpin family
B Family I11: ecotin family
B Family I17: WAP-type family
B Family I25: cystatin family
B Family I27: calpastatin family
B Family I32: IAP family
B Family I34: IA3 family
B Family I35: timp family
B Family I39: alpha2M family
B Family I47: latexin family
B Family I49: proSAAS family
B Family I51: IC family
B Family I57: staphostatin B family
B Family I63
B Family I80
B Family I87
B Family I93
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 13, 2023
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Classification taken and modified from MEROPS