+D
#
Mitochondrial Biogenesis - Sus scrofa (pig)
%
!
AMitochondrial DNA transcription, translation, and replication factors
B Mitochondrial DNA-encoded proteins
C Mitochondrial respiratory chain complex I
D 808501 ND1; NADH dehydrogenase subunit 1 K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
D 808502 ND2; NADH dehydrogenase subunit 2 K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
D 808508 ND3; NADH dehydrogenase subunit 3 K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
D 808510 ND4; NADH dehydrogenase subunit 4 K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
D 808509 ND4L; NADH dehydrogenase subunit 4L K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
D 808511 ND5; NADH dehydrogenase subunit 5 K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
D 808512 ND6; NADH dehydrogenase subunit 6 K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
C Mitochondrial respiratory chain complex III
D 808513 CYTB; cytochrome b K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
C Cytochrome c oxidase
D 808503 COX1; cytochrome c oxidase subunit I K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
D 808504 COX2; cytochrome c oxidase subunit II K02261 COX2; cytochrome c oxidase subunit 2
D 808507 COX3; cytochrome c oxidase subunit III K02262 COX3; cytochrome c oxidase subunit 3
C F-type ATPase
D 808505 ATP8; ATP synthase F0 subunit 8 K02125 ATPeF08; F-type H+-transporting ATPase subunit 8
D 808506 ATP6; ATP synthase F0 subunit 6 K02126 ATPeF0A; F-type H+-transporting ATPase subunit a
B Mitochondrial transcription and translation factors
C Mitochondrial RNA polymerase
D 110259379 POLRMT; DNA-directed RNA polymerase, mitochondrial isoform X1 K10908 POLRMT; DNA-directed RNA polymerase, mitochondrial [EC:2.7.7.6]
C Mitochondrial transcription factors
D 397279 TFAM; transcription factor A, mitochondrial precursor K11830 TFAM; transcription factor A, mitochondrial
D 100147809 TFB1M; dimethyladenosine transferase 1, mitochondrial K15266 TFB1M; dimethyladenosine transferase 1, mitochondrial [EC:2.1.1.-]
D 102161798 TFB2M; dimethyladenosine transferase 2, mitochondrial isoform X1 K17653 TFB2M; dimethyladenosine transferase 2, mitochondrial [EC:2.1.1.-]
C Mitochondrial translation factors
D 100627723 MTIF2; translation initiation factor IF-2, mitochondrial isoform X1 K02519 infB; translation initiation factor IF-2
D 100156178 MTIF3; translation initiation factor IF-3, mitochondrial isoform X4 K02520 infC; translation initiation factor IF-3
D 100622167 TSFM; elongation factor Ts, mitochondrial K02357 tsf; elongation factor Ts
D 100516488 TUFM; elongation factor Tu, mitochondrial K02358 tuf; elongation factor Tu
D 100517638 GFM2; ribosome-releasing factor 2, mitochondrial isoform X1 K02355 fusA; elongation factor G
D 100620441 GFM1; elongation factor G, mitochondrial isoform X1 K02355 fusA; elongation factor G
D 100516386 MTERF1; transcription termination factor 1, mitochondrial isoform X1 K15031 MTERF; mitochondrial transcription termination factor family protein
D 100152022 MTERF2; LOW QUALITY PROTEIN: transcription termination factor 2, mitochondrial K15031 MTERF; mitochondrial transcription termination factor family protein
D 100152384 MTERF3; transcription termination factor 3, mitochondrial isoform X2 K15031 MTERF; mitochondrial transcription termination factor family protein
D 100512374 MTERF4; transcription termination factor 4, mitochondrial isoform X1 K15031 MTERF; mitochondrial transcription termination factor family protein
D 100516681 GUF1; translation factor GUF1, mitochondrial isoform X1 K21594 GUF1; translation factor GUF1, mitochondrial [EC:3.6.5.-]
C RNase MRP
D 100739449 POP1; ribonucleases P/MRP protein subunit POP1 K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D 100523065 POP4; ribonuclease P protein subunit p29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D 100151786 POP5; ribonuclease P/MRP protein subunit POP5 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D 100156540 RPP30; ribonuclease P protein subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D 100627239 POP7; ribonuclease P protein subunit p20 K14527 RPP20; ribonuclease P/MRP protein subunit RPP20 [EC:3.1.26.5]
D 100157338 RPP25; ribonuclease P protein subunit p25 K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 100522095 RPP25L; ribonuclease P protein subunit p25-like protein K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 100626611 RPP38; ribonuclease P protein subunit p38 K14523 RPP38; ribonucleases P/MRP protein subunit RPP38 [EC:3.1.26.5]
D 110255215 RPP40; ribonuclease P protein subunit p40 isoform X1 K14530 RPP40; ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]
C Mitochondrial ribonuclease P
D 100522163 TRMT10C; mitochondrial ribonuclease P protein 1 isoform X1 K17654 TRMT10C; mitochondrial ribonuclease P protein 1 [EC:2.1.1.-]
D 100524293 HSD17B10; 3-hydroxyacyl-CoA dehydrogenase type-2 isoform X2 K08683 HSD17B10; 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178]
D 100519610 KIAA0391; mitochondrial ribonuclease P protein 3 K17655 MRPP3; mitochondrial ribonuclease P protein 3
C Other mitochondrial DNA transcription and translation factors
D 100156215 MSS51; putative protein MSS51 homolog, mitochondrial K17656 MSS51; mitochondrial splicing suppressor protein 51
D 100522515 TEFM; transcription elongation factor, mitochondrial K17658 TEFM; transcription elongation factor, mitochondrial
D 102160620 PTCD1; LOW QUALITY PROTEIN: pentatricopeptide repeat-containing protein 1, mitochondrial K17710 PTCD1; pentatricopeptide repeat domain-containing protein 1
D 100519399 PTCD2; pentatricopeptide repeat-containing protein 2, mitochondrial isoform X1 K17711 PTCD2; pentatricopeptide repeat domain-containing protein 2
D 100517886 PTCD3; pentatricopeptide repeat domain-containing protein 3, mitochondrial K17659 PTCD3; pentatricopeptide repeat domain-containing protein 3
D 100518989 DHX30; putative ATP-dependent RNA helicase DHX30 isoform X3 K13185 DHX30; ATP-dependent RNA helicase DHX30 [EC:5.6.2.6]
D 654300 UQCC; ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog K17662 CBP3; cytochrome b pre-mRNA-processing protein 3
D 100155926 AFG1L; lactation elevated protein 1 isoform X1 K18798 AFG1; peroxisome-assembly ATPase [EC:3.6.4.7]
D 100737094 ATP23; mitochondrial inner membrane protease ATP23 homolog isoform X1 K18156 ATP23; mitochondrial inner membrane protease ATP23 [EC:3.4.24.-]
D 100155960 SUPV3L1; LOW QUALITY PROTEIN: ATP-dependent RNA helicase SUPV3L1, mitochondrial K17675 SUPV3L1; ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:5.6.2.6]
D 100153212 LACTB2; endoribonuclease LACTB2 K16639 LACTB2; endoribonuclease LACTB2 [EC:3.1.27.-]
D 403155 SLC25A6; ADP/ATP translocase 3 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D 100158185 SLC25A5; ADP/ATP translocase 2 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D 100517196 SLC25A4; ADP/ATP translocase 1 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D 100518564 SLC25A31; ADP/ATP translocase 4 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D 100153622 SLC25A37; LOW QUALITY PROTEIN: mitoferrin-1 K15113 SLC25A28_37; solute carrier family 25 (mitochondrial iron transporter), member 28/37
D 100526017 SLC25A28; mitoferrin-2 isoform X1 K15113 SLC25A28_37; solute carrier family 25 (mitochondrial iron transporter), member 28/37
D 106508670 MALSU1; mitochondrial assembly of ribosomal large subunit protein 1 K25803 MALSU1; mitochondrial assembly of ribosomal large subunit protein 1
D 100518578 ERAL1; GTPase Era, mitochondrial isoform X1 K03595 era; GTPase
D 100621140 YARS; tyrosine--tRNA ligase, cytoplasmic isoform X1 K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 100624597 YARS2; tyrosine--tRNA ligase, mitochondrial K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 100525981 LARS; LOW QUALITY PROTEIN: leucine--tRNA ligase, cytoplasmic K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 100513625 LARS2; probable leucine--tRNA ligase, mitochondrial K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 100624574 DARS2; LOW QUALITY PROTEIN: aspartate--tRNA ligase, mitochondrial K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 100512260 GARS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D 414410 RARS; arginine--tRNA ligase, cytoplasmic K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 100518457 RARS2; probable arginine--tRNA ligase, mitochondrial isoform X1 K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 100627457 QRSL1; glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial isoform X1 K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D 100518383 GATB; glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial isoform X4 K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D 100153423 GATC; glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D 100517235 MTPAP; poly(A) RNA polymerase, mitochondrial K18060 MTPAP; poly(A) RNA polymerase, mitochondrial [EC:2.7.7.19]
D 100157651 PDE12; 2',5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
D 100153322 MTG1; mitochondrial ribosome-associated GTPase 1 isoform X6 K19828 MTG1; mitochondrial GTPase 1
D 100621115 nitric oxide-associated protein 1-like isoform X1 K19832 NOA1; nitric oxide-associated protein 1
D 100625260 NSUN3; tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial K21969 NSUN3; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.-]
D 100524686 NSUN4; LOW QUALITY PROTEIN: 5-methylcytosine rRNA methyltransferase NSUN4 K21970 NSUN4; 5-methylcytosine rRNA methyltransferase NSUN4 [EC:2.1.1.-]
D 100153857 RPUSD3; RNA pseudouridylate synthase domain-containing protein 3 isoform X1 K22537 RPUSD3; mitochondrial RNA pseudouridine synthase RPUSD3 [EC:5.4.99.-]
D 100514357 RPUSD4; RNA pseudouridylate synthase domain-containing protein 4 K22538 RPUSD4; mitochondrial RNA pseudouridine synthase RPUSD4 [EC:5.4.99.-]
D 100513850 RCC1L; RCC1-like G exchanging factor-like protein K23495 RCC1L; RCC1-like G exchanging factor-like protein
D 110261557 NGRN; neugrin K23496 NGRN; neugrin
D 100157964 TRUB2; probable tRNA pseudouridine synthase 2 isoform X1 K23497 TRUB2; mitochondrial mRNA pseudouridine synthase TRUB2 [EC:5.4.99.-]
D 100517314 FASTKD2; FAST kinase domain-containing protein 2, mitochondrial K18190 FASTKD2; FAST kinase domain-containing protein 2
D 100152517 C14H12orf65; LOW QUALITY PROTEIN: probable peptide chain release factor C12orf65 homolog, mitochondrial K23498 COXPD7; peptide chain release factor
D 100156656 RMND1; required for meiotic nuclear division protein 1 homolog K23499 RMND1; required for meiotic nuclear division protein 1
D 100516986 GRSF1; G-rich sequence factor 1 isoform X1 K24984 GRSF1; G-rich sequence factor 1
D 100517930 METTL15; LOW QUALITY PROTEIN: probable methyltransferase-like protein 15 K25876 METTL15; 12S rRNA N4-methylcytidine (m4C) methyltransferase [EC:2.1.1.-]
D 100516439 C5H12orf10; UPF0160 protein MYG1, mitochondrial K25877 MYG1; MYG1 exonuclease [EC:3.1.-.-]
D 100157575 C1H6orf203; uncharacterized protein C6orf203 homolog K26186 MTRES1; mitochondrial transcription rescue factor 1
B Mitochondrial DNA replication factors
C Mitochondrial DNA polymerase
D 100157469 POLG; DNA polymerase subunit gamma-1 K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
D 110255987 POLG2; LOW QUALITY PROTEIN: DNA polymerase subunit gamma-2, mitochondrial K02333 POLG2; DNA polymerase gamma 2
D 100515586 PRIMPOL; DNA-directed primase/polymerase protein isoform X1 K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Mitochondrial DNA maintenance factors
D 100514888 ENDOG; endonuclease G, mitochondrial K01173 ENDOG; endonuclease G, mitochondrial
D 100738618 MGME1; LOW QUALITY PROTEIN: mitochondrial genome maintenance exonuclease 1 K19465 MGME1; mitochondrial genome maintenance exonuclease 1 [EC:3.1.-.-]
D 100515859 EXOG; nuclease EXOG, mitochondrial isoform X1 K15050 EXOG; nuclease EXOG, mitochondrial
D 100625408 TWNK; twinkle protein, mitochondrial K17680 PEO1; twinkle protein [EC:5.6.2.3]
D 100737608 PIF1; ATP-dependent DNA helicase PIF1 isoform X1 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
C Other Mitochondrial DNA replication factors
D 100512994 SSBP1; single-stranded DNA-binding protein, mitochondrial isoform X1 K03111 ssb; single-strand DNA-binding protein
D 100525876 LOW QUALITY PROTEIN: ATPase family AAA domain-containing protein 3 K17681 ATAD3A_B; ATPase family AAA domain-containing protein 3A/B
D 100153818 C7H6orf125; uncharacterized protein LOC100153818 K17682 MNF1; mitochondrial nucleoid factor 1
#
AMitochondrial protein import machinery
B Endoplasmic reticulum membrane and cytosol
C ER-mitochondria encounter structure (ERMES) complex
C Other ER-memrane and cytosol factors
D 100521133 DNAJA2; dnaJ homolog subfamily A member 2 K09503 DNAJA2; DnaJ homolog subfamily A member 2
D 100157194 TOMM34; mitochondrial import receptor subunit TOM34 K17766 TOM34; mitochondrial import receptor subunit TOM34
D 100523466 RHOT1; mitochondrial Rho GTPase 1 isoform X1 K07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
D 396648 HSP70.2; heat shock 70 kDa protein 1B K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 100144518 HSPA1L; heat shock 70 kDa protein 1-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 396906 HSPA6; heat shock 70 kDa protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 100511890 HSPA8; heat shock cognate 71 kDa protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 100511065 AIP; AH receptor-interacting protein isoform X1 K17767 AIP; AH receptor-interacting protein
D 100524458 AIPL1; aryl-hydrocarbon-interacting protein-like 1 isoform X1 K17767 AIP; AH receptor-interacting protein
B Outer membrane
C Transporter outer membrane (TOM) complex
D 100524985 TOMM40L; mitochondrial import receptor subunit TOM40B isoform X1 K11518 TOM40; mitochondrial import receptor subunit TOM40
D 102165927 TOMM40; mitochondrial import receptor subunit TOM40 homolog K11518 TOM40; mitochondrial import receptor subunit TOM40
D 100523641 TOMM70; mitochondrial import receptor subunit TOM70 K17768 TOM70; mitochondrial import receptor subunit TOM70
D 100520786 TOMM22; mitochondrial import receptor subunit TOM22 homolog K17769 TOM22; mitochondrial import receptor subunit TOM22
D 100739656 mitochondrial import receptor subunit TOM22 homolog K17769 TOM22; mitochondrial import receptor subunit TOM22
D 100152814 TOMM20; mitochondrial import receptor subunit TOM20 homolog K17770 TOM20; mitochondrial import receptor subunit TOM20
D 100515293 TOMM20L; TOMM20-like protein 1 isoform X2 K17770 TOM20; mitochondrial import receptor subunit TOM20
D 100037982 TOMM7; mitochondrial import receptor subunit TOM7 homolog K17771 TOM7; mitochondrial import receptor subunit TOM7
D 106504412 TOMM6; mitochondrial import receptor subunit TOM6 homolog K17772 TOM6; mitochondrial import receptor subunit TOM6
D 100520533 TOMM5; mitochondrial import receptor subunit TOM5 homolog K17773 TOM5; mitochondrial import receptor subunit TOM5
C TOB/SAM complex
D 100626494 SAMM50; sorting and assembly machinery component 50 homolog isoform X1 K07277 SAM50; outer membrane protein insertion porin family
C Porin
D 397010 VDAC1; voltage-dependent anion-selective channel protein 1 K05862 VDAC1; voltage-dependent anion channel protein 1
D 397659 VDAC2; voltage-dependent anion-selective channel protein 2 K15040 VDAC2; voltage-dependent anion channel protein 2
D 397651 VDAC3; voltage-dependent anion-selective channel protein 3 K15041 VDAC3; voltage-dependent anion channel protein 3
C ERMES complex
C Other outer membrane factor
D 100512828 MTX3; metaxin-3 isoform X3 K17776 MTX; metaxin
D 664654 MTX1; metaxin-1 K17776 MTX; metaxin
D 733591 MTX2; metaxin-2 K17776 MTX; metaxin
D 100514070 MYO19; unconventional myosin-XIX isoform X1 K25838 MYO19; myosin XIX
D 100622470 ARMCX1; armadillo repeat-containing X-linked protein 1 isoform X1 K26187 ARMCX1; armadillo repeat-containing X-linked protein 1
D 100521941 ARMCX2; armadillo repeat-containing X-linked protein 2 K26188 ARMCX2; armadillo repeat-containing X-linked protein 2
D 100521421 ARMCX3; armadillo repeat-containing X-linked protein 3 K26189 ARMCX3; armadillo repeat-containing X-linked protein 3
D 100520992 protein ARMCX6 K26190 ARMCX6; armadillo repeat-containing X-linked protein 6
D 100516871 MARC1; mitochondrial amidoxime-reducing component 1 isoform X1 K27318 MTARC; mitochondrial amidoxime-reducing component [EC:1.7.-.-]
B Inter membrane space
C Transporter inner membrane (TIM) 9/10 complex
D 100621083 TIMM9; mitochondrial import inner membrane translocase subunit Tim9 K17777 TIM9; mitochondrial import inner membrane translocase subunit TIM9
D 100623727 TIMM10B; mitochondrial import inner membrane translocase subunit Tim10 B K17779 TIM10B; mitochondrial import inner membrane translocase subunit TIM10B
C TIM8/13 complex
D 100517443 TIMM8A; mitochondrial import inner membrane translocase subunit Tim8 A K17780 TIM8; mitochondrial import inner membrane translocase subunit TIM8
D 100516748 TIMM8B; mitochondrial import inner membrane translocase subunit Tim8 B K17780 TIM8; mitochondrial import inner membrane translocase subunit TIM8
D 100620885 TIMM13; mitochondrial import inner membrane translocase subunit Tim13 K17781 TIM13; mitochondrial import inner membrane translocase subunit TIM13
C Mitochondrial intermembrane space assembly (MIA) complex
D 100154663 CHCHD4; mitochondrial intermembrane space import and assembly protein 40 K17782 MIA40; mitochondrial intermembrane space import and assembly protein 40
D 100515774 GFER; FAD-linked sulfhydryl oxidase ALR K17783 ERV1; mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2]
B Inner mambrane
C MICOS complex
D 100623381 MINOS1; MICOS complex subunit MIC10 K17784 MICOS10; MICOS complex subunit MIC10
D 100738042 MICOS complex subunit MIC10-like K17784 MICOS10; MICOS complex subunit MIC10
D 100738124 IMMT; MICOS complex subunit MIC60 isoform X2 K17785 IMMT; MICOS complex subunit MIC60
D 100037978 C2H19orf70; MICOS complex subunit MIC13 precursor K24624 MICOS13; MICOS complex subunit MIC13
D 414383 CHCHD3; MICOS complex subunit MIC19 K17563 CHCHD3; MICOS complex subunit MIC19
D 100624760 CHCHD6; LOW QUALITY PROTEIN: MICOS complex subunit MIC25 K17564 CHCHD6; MICOS complex subunit MIC25
D 100525438 APOO; MICOS complex subunit MIC26 K24625 APOO; MICOS complex subunit MIC26
D 100153260 APOOL; MICOS complex subunit MIC27 isoform X1 K24626 APOOL; MICOS complex subunit MIC27
C MICOS complex (yeast)
D 100623381 MINOS1; MICOS complex subunit MIC10 K17784 MICOS10; MICOS complex subunit MIC10
D 100738042 MICOS complex subunit MIC10-like K17784 MICOS10; MICOS complex subunit MIC10
D 100738124 IMMT; MICOS complex subunit MIC60 isoform X2 K17785 IMMT; MICOS complex subunit MIC60
C TIM22 complex
D 100621364 TIMM22; mitochondrial import inner membrane translocase subunit Tim22 isoform X2 K17790 TIM22; mitochondrial import inner membrane translocase subunit TIM22
C TIM23 complex
D 100157391 mitochondrial import inner membrane translocase subunit Tim23 isoform X1 K17794 TIM23; mitochondrial import inner membrane translocase subunit TIM23
D 100621014 TIMM17B; mitochondrial import inner membrane translocase subunit Tim17-B K17795 TIM17; mitochondrial import inner membrane translocase subunit TIM17
D 110255663 TIMM17A; mitochondrial import inner membrane translocase subunit Tim17-A K17795 TIM17; mitochondrial import inner membrane translocase subunit TIM17
D 100622200 TIMM21; mitochondrial import inner membrane translocase subunit Tim21 K17796 TIM21; mitochondrial import inner membrane translocase subunit TIM21
D 100623818 TIMM50; LOW QUALITY PROTEIN: mitochondrial import inner membrane translocase subunit TIM50 K17496 TIM50; mitochondrial import inner membrane translocase subunit TIM50
C Mitochondrial calcium uniporter complex
D 100153794 MCU; calcium uniporter protein, mitochondrial isoform X1 K20858 MCU; calcium uniporter protein, mitochondrial
D 100155980 MICU1; calcium uptake protein 1, mitochondrial K22827 MICU1; calcium uptake protein 1, mitochondrial
D 100623901 MICU2; calcium uptake protein 2, mitochondrial isoform X1 K22828 MICU2; calcium uptake protein 2, mitochondrial
D 100623186 MCUB; calcium uniporter regulatory subunit MCUb, mitochondrial isoform X1 K22829 MCUB; calcium uniporter regulatory subunit MCUb, mitochondrial
D 100737924 SMDT1; essential MCU regulator, mitochondrial K22830 SMDT1; essential MCU regulator, mitochondrial
D 100520967 MCUR1; mitochondrial calcium uniporter regulator 1 isoform X1 K22137 MCUR1; mitochondrial calcium uniporter regulator 1
C Other inner membrane factors
D 100514302 LETM1; LETM1 and EF-hand domain-containing protein 1, mitochondrial K17800 LETM1; LETM1 and EF-hand domain-containing protein 1, mitochondrial
D 100514893 IMMP1L; mitochondrial inner membrane protease subunit 1 K09647 IMP1; mitochondrial inner membrane protease subunit 1 [EC:3.4.21.-]
D 100521052 IMMP2L; mitochondrial inner membrane protease subunit 2 isoform X1 K09648 IMP2; mitochondrial inner membrane protease subunit 2 [EC:3.4.21.-]
D 100627094 TMEM126A; transmembrane protein 126A K18157 TMEM126A; transmembrane protein 126A
D 100515596 MPC1L; mitochondrial pyruvate carrier 1-like protein K22138 MPC1; mitochondrial pyruvate carrier 1
D 100513634 MPC1; mitochondrial pyruvate carrier 1 K22138 MPC1; mitochondrial pyruvate carrier 1
D 100154777 MPC2; mitochondrial pyruvate carrier 2 K22139 MPC2; mitochondrial pyruvate carrier 2
D 100152325 CHCHD10; coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial K22759 CHCHD10; coiled-coil-helix-coiled-coil-helix domain-containing protein 10
B Matrix
C MMC/PAM proteins
D 100521124 TIMM44; mitochondrial import inner membrane translocase subunit TIM44 K17804 TIM44; mitochondrial import inner membrane translocase subunit TIM44
D 100521183 HSPA9; stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
D 100513650 GRPEL2; grpE protein homolog 2, mitochondrial K03687 GRPE; molecular chaperone GrpE
D 100622145 GRPEL1; LOW QUALITY PROTEIN: grpE protein homolog 1, mitochondrial K03687 GRPE; molecular chaperone GrpE
D 100154656 DNAJC19; mitochondrial import inner membrane translocase subunit TIM14 K09539 DNAJC19; DnaJ homolog subfamily C member 19
C Other matrix factors
D 100627838 PMPCA; LOW QUALITY PROTEIN: mitochondrial-processing peptidase subunit alpha K01412 PMPCA; mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]
D 100514358 PMPCB; mitochondrial-processing peptidase subunit beta K17732 PMPCB; mitochondrial-processing peptidase subunit beta [EC:3.4.24.64]
D 100155148 MIPEP; mitochondrial intermediate peptidase K01410 MIPEP; mitochondrial intermediate peptidase [EC:3.4.24.59]
D 492279 HSPD1; 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D 397575 HSPE1; 10 kDa heat shock protein, mitochondrial K04078 groES; chaperonin GroES
D 100624182 DNAJA3; dnaJ homolog subfamily A member 3, mitochondrial isoform X2 K09504 DNAJA3; DnaJ homolog subfamily A member 3
D 100524902 TAMM41; phosphatidate cytidylyltransferase, mitochondrial isoform X1 K17807 TAM41; mitochondrial translocator assembly and maintenance protein 41
D 110258077 DNLZ; DNL-type zinc finger protein K17808 ZIM17; mitochondrial protein import protein ZIM17
D 106504117 ETHE1; LOW QUALITY PROTEIN: persulfide dioxygenase ETHE1, mitochondrial K17725 ETHE1; sulfur dioxygenase [EC:1.13.11.18]
D 100624252 POLDIP2; polymerase delta-interacting protein 2 K17809 POLDIP2; polymerase delta-interacting protein 2
#
AMitochondrial quality control factors
B Regulator of mitochondrial biogenesis
C Ubiquitas transcription factors
D 100736562 CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 K05870 CREB1; cyclic AMP-responsive element-binding protein 1
D 100517638 GFM2; ribosome-releasing factor 2, mitochondrial isoform X1 K02355 fusA; elongation factor G
D 100620441 GFM1; elongation factor G, mitochondrial isoform X1 K02355 fusA; elongation factor G
D 396575 SP1; transcription factor Sp1 isoform X1 K04684 SP1; transcription factor Sp1
D 102162035 YY1; transcriptional repressor protein YY1 K09201 YY; transcription factor YY
D 100152294 GABPB2; GA-binding protein subunit beta-2 isoform X1 K09454 GABPB; GA-binding protein transcription factor, beta
D 100157164 GABPB1; GA-binding protein subunit beta-1 isoform X7 K09454 GABPB; GA-binding protein transcription factor, beta
D 397279 TFAM; transcription factor A, mitochondrial precursor K11830 TFAM; transcription factor A, mitochondrial
C Nuclear respiratory factors
D 100517203 NRF1; nuclear respiratory factor 1 isoform X1 K11831 NRF1; nuclear respiratory factor 1
D 100516343 NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X4 K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
D 397417 MT1A; metallothionein-1A K14739 MT1_2; metallothionein 1/2
D 396827 MT-2B; metallothionein-2A K14739 MT1_2; metallothionein 1/2
D 100739663 metallothionein-1C K14739 MT1_2; metallothionein 1/2
D 397123 MT3; metallothionein-3 K14740 MT3; metallothionein 3
D 110260925 MT4; metallothionein-4 K14741 MT4; metallothionein 4
C Coactivators
D 397013 PPARGC1A; peroxisome proliferator-activated receptor gamma coactivator 1-alpha K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
D 100329221 PPARGC1B; peroxisome proliferator-activated receptor gamma coactivator 1-beta K17962 PPARGC1B; peroxisome proliferator-activated receptor gamma coactivator 1-beta
D 100329222 PPRC1; LOW QUALITY PROTEIN: peroxisome proliferator-activated receptor gamma coactivator-related protein 1 K17963 PPRC1; peroxisome proliferator-activated receptor gamma coactivator-related protein 1
D 100523662 CRTC1; LOW QUALITY PROTEIN: CREB-regulated transcription coactivator 1 K15309 CRTC1; CREB-regulated transcription coactivator 1
D 100156226 EP300; LOW QUALITY PROTEIN: histone acetyltransferase p300 K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
D 100620215 CREBBP; CREB-binding protein K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
C Proteins involved in Fe-S cluster biogenesis
D 100156145 NFS1; cysteine desulfurase, mitochondrial K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D 100621691 ISCU; LOW QUALITY PROTEIN: iron-sulfur cluster assembly enzyme ISCU, mitochondrial K22068 ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial
D 100522444 LYRM4; LYR motif-containing protein 4 isoform X1 K22069 LYRM4; LYR motif-containing protein 4
D 110255665 FXN; LOW QUALITY PROTEIN: frataxin, mitochondrial K19054 FXN; frataxin [EC:1.16.3.1]
D 397133 FDX1; adrenodoxin, mitochondrial precursor K22070 FDX1; ferredoxin-1, mitochondrial
D 100526209 ferredoxin-2, mitochondrial isoform X2 K22071 FDX2; ferredoxin-2, mitochondrial
D 100512919 FDXR; NADPH:adrenodoxin oxidoreductase, mitochondrial K18914 FDXR; adrenodoxin-NADP+ reductase [EC:1.18.1.6]
D 100521183 HSPA9; stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
D 110256862 HSCB; iron-sulfur cluster co-chaperone protein HscB, mitochondrial isoform X1 K04082 hscB; molecular chaperone HscB
D 100626868 SIL1; nucleotide exchange factor SIL1 K14001 SIL1; nucleotide exchange factor SIL1
D 100154744 GLRX5; glutaredoxin-related protein 5, mitochondrial K07390 grxD; monothiol glutaredoxin
D 100516824 ISCA1; iron-sulfur cluster assembly 1 homolog, mitochondrial isoform X1 K22063 ISCA1; iron-sulfur cluster assembly 1
D 100738266 ISCA2; iron-sulfur cluster assembly 2 homolog, mitochondrial K22072 ISCA2; iron-sulfur cluster assembly 2
D 100513524 IBA57; putative transferase CAF17, mitochondrial K22073 IBA57; transferase CAF17, mitochondrial [EC:2.1.-.-]
D 102165918 NFU1; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform X1 K22074 NFU1; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
D 100152975 BOLA1; bolA-like protein 1 K22066 BOLA1; BolA-like protein 1
D 100737769 BOLA3; bolA-like protein 3 isoform X1 K22075 BOLA3; BolA-like protein 3
D 100049699 SFXN1; sideroflexin-1 K23500 SFXN1_3; sideroflexin-1/3
D 100154194 SFXN3; sideroflexin-3 K23500 SFXN1_3; sideroflexin-1/3
D 102157879 SFXN2; sideroflexin-2 isoform X5 K23501 SFXN2; sideroflexin-2
D 100154966 SFXN4; sideroflexin-4 K23502 SFXN4; sideroflexin-4
D 100621633 SFXN5; sideroflexin-5 K23503 SFXN5; sideroflexin-5
C Other regulator of mitochondrial biogenesis
D 399527 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
D 399528 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
D 100519258 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform isoform X2 K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
D 102166829 DHTKD1; probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial isoform X1 K15791 DHKTD1; 2-oxoadipate dehydrogenase E1 component [EC:1.2.4.-]
D 100156082 FBXL4; F-box/LRR-repeat protein 4 K10270 FBXL4; F-box and leucine-rich repeat protein 4
D 100523834 HCFC1; LOW QUALITY PROTEIN: host cell factor 1 K14966 HCFC1; host cell factor 1
D 100514768 HCFC2; host cell factor 2 K27390 HCFC2; host cell factor 2
D 397014 HTT; huntingtin K04533 HD; huntingtin
D 100322868 ESRRA; steroid hormone receptor ERR1 K08552 NR3B1; estrogen-related receptor alpha
D 100151940 ESRRB; steroid hormone receptor ERR2 isoform X3 K08553 NR3B2; estrogen-related receptor beta
D 100622056 ESRRG; estrogen-related receptor gamma isoform X6 K08554 NR3B3; estrogen-related receptor gamma
D 106505834 NRIP1; nuclear receptor-interacting protein 1 K17965 NRIP1; nuclear receptor-interacting protein 1
D 397504 PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D 100145903 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D 100511917 LONP1; lon protease homolog, mitochondrial K08675 PRSS15; ATP-dependent Lon protease [EC:3.4.21.53]
D 751859 SIRT1; NAD-dependent protein deacetylase sirtuin-1 K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
D 100523935 SERAC1; protein SERAC1 isoform X2 K23504 SERAC1; protein SERAC1
D 100522472 UXT; protein UXT K26537 UXT; protein UXT
D 102165012 PERM1; PGC-1 and ERR-induced regulator in muscle protein 1 isoform X1 K26738 PERM1; PGC-1 and ERR-induced regulator in muscle protein 1
B Mitochondrial respiratory chain complex assembly factors
C Complex-I assembly factors
D 100524355 NDUFAF1; complex I intermediate-associated protein 30, mitochondrial K18159 NDUFAF1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1
D 100738470 NDUFAF2; mimitin, mitochondrial K18160 NDUFAF2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2
D 100156018 NDUFAF3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 K09008 NDUFAF3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3
D 100157673 NDUFAF4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 K18161 NDUFAF4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4
D 100520522 NDUFAF5; arginine-hydroxylase NDUFAF5, mitochondrial isoform X1 K18162 NDUFAF5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 [EC:2.1.1.-]
D 100152224 NDUFAF6; NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform X1 K18163 NDUFAF6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 6
D 100522486 NDUFAF7; protein arginine methyltransferase NDUFAF7, mitochondrial isoform X2 K18164 NDUFAF7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7
D 100626290 NDUFAF8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8 K24726 NDUFAF8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8
D 100626990 TMEM126B; complex I assembly factor TMEM126B, mitochondrial K18165 TMEM126B; complex I assembly factor TMEM126B
D 100519412 ECSIT; evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform X1 K04405 ECSIT; evolutionarily conserved signaling intermediate in Toll pathway
D 100621922 ACAD9; acyl-CoA dehydrogenase family member 9, mitochondrial isoform X1 K15980 ACAD9; acyl-CoA dehydrogenase family member 9 [EC:1.3.99.-]
D 100736652 NUBPL; iron-sulfur protein NUBPL isoform X2 K03593 mrp; ATP-binding protein involved in chromosome partitioning
D 100513997 FOXRED1; FAD-dependent oxidoreductase domain-containing protein 1 K18166 FOXRED1; FAD-dependent oxidoreductase domain-containing protein 1
D 100519752 RTN4IP1; reticulon-4-interacting protein 1, mitochondrial isoform X1 K23164 RTN4IP1; reticulon-4-interacting protein 1, mitochondrial
D 110256419 TIMMDC1; complex I assembly factor TIMMDC1, mitochondrial K23505 TIMMDC1; complex I assembly factor TIMMDC1
C Complex-II assembly factors
D 100521971 SDHAF1; succinate dehydrogenase assembly factor 1, mitochondrial K18167 SDHAF1; succinate dehydrogenase assembly factor 1
D 100519294 SDHAF2; succinate dehydrogenase assembly factor 2, mitochondrial K18168 SDHAF2; succinate dehydrogenase assembly factor 2
C Complex-III assembly factors
D 100626589 BCS1L; BCS1-like K08900 BCS1; mitochondrial chaperone BCS1
D 102165221 TTC19; tetratricopeptide repeat protein 19, mitochondrial K18169 TTC19; tetratricopeptide repeat protein 19, mitochondrial
D 100519080 LYRM7; complex III assembly factor LYRM7 isoform X4 K18170 LYRM7; complex III assembly factor LYRM7
D 654300 UQCC; ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog K17662 CBP3; cytochrome b pre-mRNA-processing protein 3
D 100153818 C7H6orf125; uncharacterized protein LOC100153818 K17682 MNF1; mitochondrial nucleoid factor 1
D 100621476 ubiquinol-cytochrome-c reductase complex assembly factor 3 K23165 UQCC3; ubiquinol-cytochrome-c reductase complex assembly factor 3
D 100514953 C3H16orf91; protein CCSMST1 K27339 UQCC4; ubiquinol-cytochrome c reductase complex assembly factor 4
D 110260781 C5H12orf73; uncharacterized protein C12orf73 homolog K27341 UQCC6; ubiquinol-cytochrome c reductase complex assembly factor 6
D 100521821 C13H7orf73; uncharacterized protein C7orf73 homolog K27319 STMP1; short transmembrane mitochondrial protein 1
C Complex-IV assembly factors
D 102164646 CMC1; COX assembly mitochondrial protein homolog isoform X1 K18171 CMC1; COX assembly mitochondrial protein 1
D 100516527 cytochrome c oxidase assembly factor 1 homolog K18173 COA1; cytochrome c oxidase assembly factor 1
D 100518575 cytochrome c oxidase assembly factor 3 homolog, mitochondrial K18175 CCDC56; cytochrome c oxidase assembly factor 3, animal type
D 100514530 cytochrome c oxidase assembly factor 4 homolog, mitochondrial K18177 COA4; cytochrome c oxidase assembly factor 4
D 100524554 cytochrome c oxidase assembly factor 5 isoform X1 K18178 COA5; cytochrome c oxidase assembly factor 5
D 100512926 cytochrome c oxidase assembly factor 6 homolog isoform X1 K18179 COA6; cytochrome c oxidase assembly factor 6
D 100627075 SELRC1; Sel1 repeat containing 1 K18180 COA7; cytochrome c oxidase assembly factor 7
D 100521863 COX10; COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D 100739396 cytochrome c oxidase assembly protein COX11, mitochondrial K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D 110260660 cytochrome c oxidase assembly protein COX14 K18181 COX14; cytochrome c oxidase assembly factor 14
D 100156375 cytochrome c oxidase assembly protein COX15 homolog isoform X1 K02259 COX15; heme a synthase [EC:1.17.99.9]
D 100525232 cytochrome c oxidase assembly protein COX16 homolog, mitochondrial K18182 COX16; cytochrome c oxidase assembly protein subunit 16
D 100156799 COX17; cytochrome c oxidase copper chaperone K02260 COX17; cytochrome c oxidase assembly protein subunit 17
D 100520317 mitochondrial inner membrane protein COX18 isoform X2 K17797 COX18; mitochondrial inner membrane protein COX18
D 100522861 cytochrome c oxidase assembly protein COX19 isoform X2 K18183 COX19; cytochrome c oxidase assembly protein subunit 19
D 100739755 cytochrome c oxidase protein 20 homolog K18184 COX20; cytochrome c oxidase assembly protein subunit 20
D 100156215 MSS51; putative protein MSS51 homolog, mitochondrial K17656 MSS51; mitochondrial splicing suppressor protein 51
D 100037981 PET100; protein PET100 homolog, mitochondrial K18186 PET100; protein PET100, animal type
D 106504161 PET117; protein PET117 homolog, mitochondrial K18188 PET117; protein PET117
D 100154992 OXA1L; LOW QUALITY PROTEIN: mitochondrial inner membrane protein OXA1L K03217 yidC; YidC/Oxa1 family membrane protein insertase
D 110256505 surfeit locus protein 1 isoform X1 K14998 SURF1; surfeit locus 1 family protein
D 100155488 LOW QUALITY PROTEIN: surfeit locus protein 1 K14998 SURF1; surfeit locus 1 family protein
D 100517855 protein SCO1 homolog, mitochondrial K07152 SCO1; protein SCO1
D 100516804 SCO2; SCO cytochrome oxidase deficient homolog 2 isoform 1 precursor K23755 SCO2; protein SCO2
D 100514364 TACO1; translational activator of cytochrome c oxidase 1 K18189 TACO1; translational activator of cytochrome c oxidase 1
D 100512225 LRPPRC; leucine-rich PPR motif-containing protein, mitochondrial K17964 LRPPRC; leucine-rich PPR motif-containing protein, mitochondrial
D 100157863 LOW QUALITY PROTEIN: apoptogenic protein 1, mitochondrial K23506 APOPT1; apoptogenic protein 1
D 110258331 APOPT1; apoptogenic protein 1, mitochondrial K23506 APOPT1; apoptogenic protein 1
D 100521821 C13H7orf73; uncharacterized protein C7orf73 homolog K27319 STMP1; short transmembrane mitochondrial protein 1
D 100620450 TMEM223; LOW QUALITY PROTEIN: transmembrane protein 223 K27342 TMEM223; transmembrane protein 223
C Complex-V assembly factors
D 100524092 ATPAF1; ATP synthase mitochondrial F1 complex assembly factor 1 isoform X1 K07555 ATPeAF1; ATP synthase mitochondrial F1 complex assembly factor 1
D 100621967 ATPAF2; ATP synthase mitochondrial F1 complex assembly factor 2 isoform X1 K07556 ATPeAF2; ATP synthase mitochondrial F1 complex assembly factor 2
D 100155813 TMEM70; transmembrane protein 70, mitochondrial isoform X1 K17966 TMEM70; transmembrane protein 70, mitochondrial
D 100523804 CUNH14orf2; 6.8 kDa mitochondrial proteolipid K18193 MP68; 6.8 kDa mitochondrial proteolipid
D 100520866 USMG5; up-regulated during skeletal muscle growth protein 5 K18194 USMG5; up-regulated during skeletal muscle growth protein 5
B Mitochondrial dynamics
C Fission and Fusion factors
D 100627612 MFN1; mitofusin-1 K21356 MFN1; mitofusin 1 [EC:3.6.5.-]
D 100512354 MFN2; mitofusin-2 isoform X2 K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
D 100522705 OPA1; dynamin-like 120 kDa protein, mitochondrial isoform X1 K17079 OPA1; optic atrophy protein 1 [EC:3.6.5.5]
D 106508274 OPA3; optic atrophy 3 protein isoform X1 K23166 OPA3; optic atrophy 3 protein
D 110256624 TRIAP1; TP53-regulated inhibitor of apoptosis 1 K17968 TRIAP1; TRIAP1/MDM35 family protein
D 100739380 PARL; presenilins-associated rhomboid-like protein, mitochondrial isoform X1 K09650 PARL; rhomboid-like protein [EC:3.4.21.105]
D 397543 BAK1; bcl-2 homologous antagonist/killer isoform X2 K14021 BAK; Bcl-2 homologous antagonist/killer
D 396633 BAX; apoptosis regulator BAX isoform X1 K02159 BAX; apoptosis regulator BAX
D 100624497 DNM1L; dynamin-1-like protein isoform X1 K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D 100622909 FIS1; mitochondrial fission 1 protein K17969 FIS1; mitochondrial fission 1 protein
D 100127140 SUMO4; small ubiquitin-related modifier 4 precursor K12160 SUMO; small ubiquitin-related modifier
D 100624225 SUMO3; small ubiquitin-related modifier 3 K12160 SUMO; small ubiquitin-related modifier
D 397044 SUMO2; small ubiquitin-related modifier 2 precursor K12160 SUMO; small ubiquitin-related modifier
D 100127139 SUMO1; small ubiquitin-related modifier 1 precursor K12160 SUMO; small ubiquitin-related modifier
D 100737265 small ubiquitin-related modifier 1-like K12160 SUMO; small ubiquitin-related modifier
D 100316852 SH3GLB1; endophilin-B1 K11248 SH3GLB1; endophilin-B1
D 100152609 MTCH1; mitochondrial carrier homolog 1 isoform 1 K17885 MTCH; mitochondrial carrier
D 100627768 MTCH2; mitochondrial carrier homolog 2 K17885 MTCH; mitochondrial carrier
D 100513442 MFF; mitochondrial fission factor K22076 MFF; mitochondrial fission factor
D 100737339 LOW QUALITY PROTEIN: mitochondrial fission factor-like K22076 MFF; mitochondrial fission factor
D 100157012 GDAP1; ganglioside-induced differentiation-associated protein 1 K22077 GDAP1; ganglioside-induced differentiation-associated protein 1
D 100625236 GDAP1L1; ganglioside-induced differentiation-associated protein 1-like 1 K22077 GDAP1; ganglioside-induced differentiation-associated protein 1
D 100625359 VAT1; synaptic vesicle membrane protein VAT-1 homolog K23167 VAT1; synaptic vesicle membrane protein VAT-1
D 100157057 MIEF1; mitochondrial dynamics protein MID51 K23507 MIEF1_2; mitochondrial dynamics protein MID51/49
D 110256130 MIEF2; mitochondrial dynamics protein MID49 K23507 MIEF1_2; mitochondrial dynamics protein MID51/49
D 110256141 PLD6; mitochondrial cardiolipin hydrolase K16862 PLD6; mitochondrial cardiolipin hydrolase [EC:3.1.4.-]
D 100625285 MIGA1; mitoguardin 1 K27289 MIGA; mitoguardin
D 100155132 MIGA2; LOW QUALITY PROTEIN: mitoguardin 2 K27289 MIGA; mitoguardin
C Actin cytoskeleton organization
D 397653 ACTG1; actin, cytoplasmic 2 K05692 ACTB_G1; actin beta/gamma 1
D 414396 ACTB; actin, cytoplasmic 1 K05692 ACTB_G1; actin beta/gamma 1
D 100512320 NAA20; N-alpha-acetyltransferase 20 isoform X1 K17972 NAA20; N-terminal acetyltransferase B complex catalytic subunit [EC:2.3.1.254]
D 100157031 NAA25; N-alpha-acetyltransferase 25, NatB auxiliary subunit K17973 NAA25; N-terminal acetyltransferase B complex non-catalytic subunit
C Mitochondrial movement
D 100524707 PHB; prohibitin K17080 PHB1; prohibitin 1
D 100627467 PHB2; prohibitin-2 K17081 PHB2; prohibitin 2
D 100152397 KTN1; kinectin K17975 KTN1; kinectin
C Retention of mitochondria
D 100624497 DNM1L; dynamin-1-like protein isoform X1 K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D 594849 MYO5A; unconventional myosin-Va isoform X8 K10357 MYO5; myosin V
D 100155557 MYO5C; unconventional myosin-Vc isoform X1 K10357 MYO5; myosin V
D 100521829 MYO5B; unconventional myosin-Vb isoform X1 K10357 MYO5; myosin V
D 100037300 XIAP; E3 ubiquitin-protein ligase XIAP K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
D 100155744 DIABLO; diablo homolog, mitochondrial K10522 DIABLO; diablo
C Morphogenesis factors
D 100157280 SNX25; LOW QUALITY PROTEIN: sorting nexin-25 K17887 SNX25; sorting nexin-25
D 100523466 RHOT1; mitochondrial Rho GTPase 1 isoform X1 K07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
D 100738124 IMMT; MICOS complex subunit MIC60 isoform X2 K17785 IMMT; MICOS complex subunit MIC60
D 100157687 MTFP1; LOW QUALITY PROTEIN: mitochondrial fission process protein 1 K17981 MTFP1; mitochondrial fission process protein 1
D 100152332 DAP3; 28S ribosomal protein S29, mitochondrial isoform X1 K17408 DAP3; small subunit ribosomal protein S29
D 100514504 NEDD4; E3 ubiquitin-protein ligase NEDD4 isoform X1 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
D 100153332 OXR1; oxidation resistance protein 1 isoform X2 K25437 OXR1; oxidation resistance protein 1
D 100525162 MSTO1; protein misato homolog 1 K27320 MSTO1; protein misato
B Mitophagy factors
C Autophagy-related proteins
D 100462716 ATG2B; autophagy-related protein 2 homolog B K17906 ATG2; autophagy-related protein 2
D 100462717 ATG2A; autophagy-related protein 2 homolog A K17906 ATG2; autophagy-related protein 2
D 100157190 ATG3; ubiquitin-like-conjugating enzyme ATG3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
D 100141400 ATG4D; cysteine protease ATG4D K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D 100156732 ATG4A; cysteine protease ATG4A isoform X1 K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D 100462748 ATG4C; cysteine protease ATG4C K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D 100462747 ATG4B; cysteine protease ATG4B K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D 100739102 ATG5; autophagy protein 5 isoform X1 K08339 ATG5; autophagy-related protein 5
D 733576 BECN1; beclin-1 K08334 BECN; beclin
D 100512673 BECN2; beclin-2 K08334 BECN; beclin
D 100462749 ATG7; ubiquitin-like modifier-activating enzyme ATG7 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D 100462752 GABARAP; gamma-aminobutyric acid receptor-associated protein K08341 GABARAP; GABA(A) receptor-associated protein
D 100521968 GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2 K08341 GABARAP; GABA(A) receptor-associated protein
D 100462751 GABARAPL1; gamma-aminobutyric acid receptor-associated protein-like 1 K08341 GABARAP; GABA(A) receptor-associated protein
D 100155182 ATG9A; autophagy-related protein 9A K17907 ATG9; autophagy-related protein 9
D 100462720 ATG9B; autophagy-related protein 9B K17907 ATG9; autophagy-related protein 9
D 100462744 ATG10; ubiquitin-like-conjugating enzyme ATG10 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
D 100462745 ATG12; ubiquitin-like protein ATG12 K08336 ATG12; ubiquitin-like protein ATG12
D 100155666 ATG14; beclin 1-associated autophagy-related key regulator K17889 ATG14L; beclin 1-associated autophagy-related key regulator
D 100462746 ATG16L1; autophagy-related protein 16-1 isoform 1 K17890 ATG16L1; autophagy-related protein 16-1
D 100511396 ATG16L2; autophagy-related protein 16-2 isoform X1 K20868 ATG16L2; autophagy-related protein 16-2
D 100462758 WIPI1; WD repeat domain phosphoinositide-interacting protein 1 K17908 WIPI1_2; autophagy-related protein 18
D 100462759 WIPI2; WD repeat domain phosphoinositide-interacting protein 2 K17908 WIPI1_2; autophagy-related protein 18
C Parkin-dependent mechanism factors
D 733673 PRKN; E3 ubiquitin-protein ligase parkin K04556 PARK2; parkin [EC:2.3.2.31]
D 100157936 RNF41; E3 ubiquitin-protein ligase NRDP1 K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 100519828 CLEC16A; protein CLEC16A isoform X1 K19513 CLEC16A; protein CLEC16A
D 100515613 PINK1; serine/threonine-protein kinase PINK1, mitochondrial K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
D 100739380 PARL; presenilins-associated rhomboid-like protein, mitochondrial isoform X1 K09650 PARL; rhomboid-like protein [EC:3.4.21.105]
D 100518718 SQSTM1; sequestosome-1 isoform X1 K14381 SQSTM1; sequestosome 1
D 100516165 TAX1BP1; tax1-binding protein 1 isoform X1 K21347 TAX1BP1; Tax1-binding protein 1
D 100523089 CALCOCO2; calcium-binding and coiled-coil domain-containing protein 2 K21348 CALCOCO2; calcium-binding and coiled-coil domain-containing protein 2
D 100519700 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1 isoform X3 K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
C Parkin-independent mechanism factors
D 100516128 ATG13; autophagy-related protein 13 isoform X1 K08331 ATG13; autophagy-related protein 13
D 100151990 ULK1; serine/threonine-protein kinase ULK1 isoform X1 K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
D 100525780 ULK2; serine/threonine-protein kinase ULK2 isoform X1 K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
D 100622699 RB1CC1; RB1-inducible coiled-coil protein 1 isoform X1 K17589 RB1CC1; RB1-inducible coiled-coil protein 1
D 397028 HSP90AA1; heat shock protein HSP 90-alpha K04079 HSP90A; molecular chaperone HtpG
D 396742 HSP90AB1; heat shock protein HSP 90-beta K04079 HSP90A; molecular chaperone HtpG
D 100141402 CDC37; hsp90 co-chaperone Cdc37 K09554 CDC37; cell division cycle protein 37
D 100621443 SMURF1; E3 ubiquitin-protein ligase SMURF1 isoform X1 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
D 100627676 SMURF2; E3 ubiquitin-protein ligase SMURF2 isoform X1 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
D 100152675 BNIP3L; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X1 K15465 BNIP3L; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
D 100518350 FUNDC1; FUN14 domain-containing protein 1 K17986 FUNDC1; FUN14 domain-containing protein 1
C Other mitophagy factors
D 397504 PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D 100145903 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D 100322893 MAP1LC3A; microtubule-associated proteins 1A/1B light chain 3A K10435 MAP1LC; microtubule-associated protein 1 light chain
D 100462754 MAP1LC3B; microtubule-associated proteins 1A/1B light chain 3B K10435 MAP1LC; microtubule-associated protein 1 light chain
D 100512852 MAP1LC3C; microtubule-associated proteins 1A/1B light chain 3C K10435 MAP1LC; microtubule-associated protein 1 light chain
D 100625110 NBR1; next to BRCA1 gene 1 protein isoform X4 K17987 NBR1; next to BRCA1 gene 1 protein
D 100521257 TECPR1; LOW QUALITY PROTEIN: tectonin beta-propeller repeat-containing protein 1 K17988 TECPR1; tectonin beta-propeller repeat-containing protein 1
D 100154908 ZFYVE1; zinc finger FYVE domain-containing protein 1 isoform X1 K17603 ZFYVE1; zinc finger FYVE domain-containing protein 1
D 396688 COASY; bifunctional coenzyme A synthase precursor K02318 COASY; phosphopantetheine adenylyltransferase / dephospho-CoA kinase [EC:2.7.7.3 2.7.1.24]
D 100514711 PLA2G6; 85/88 kDa calcium-independent phospholipase A2 isoform X2 K16343 PLA2G6; calcium-independent phospholipase A2 [EC:3.1.1.4]
D 102159538 C6H19orf12; protein C19orf12 homolog K23168 MPAN; protein MPAN
D 396564 FUNDC2; FUN14 domain-containing protein 2 K24308 FUNDC2; FUN14 domain-containing protein 2
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 14, 2024