+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Tribolium castaneum (red flour beetle)</h2>
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A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
E        659894 mRNA cap guanine-N7 methyltransferase	K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56] 
E        660879 mRNA-capping enzyme	K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74] 
E        655114 cyclin-dependent kinase 7	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        655843 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1	K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57] 
E        658920 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2	K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296] 
E        103314936 uncharacterized LOC103314936	K18708 FAM103A1; RNMT-activating mini protein 
D      Cap binding complex
E        661829 nuclear cap-binding protein subunit 1	K12882 NCBP1; nuclear cap-binding protein subunit 1 
E        663946 nuclear cap-binding protein subunit 2	K12883 NCBP2; nuclear cap-binding protein subunit 2 
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
E        657997 cleavage and polyadenylation specificity factor subunit 5	K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5 
E        658420 cleavage and polyadenylation specificity factor subunit CG7185	K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7 
D      Pre-mRNA cleavage factor IIm (CFIIm)
E        663900 protein CLP1 homolog	K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78] 
E        659455 kinesin-5D; kinesin 5D	K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 
D      Cleavage and polyadenylation specificity factor (CPSF) complex
E        656498 cleavage and polyadenylation specificity factor subunit 1	K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1 
E        659785 probable cleavage and polyadenylation specificity factor subunit 2	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        103314846 cleavage and polyadenylation specificity factor 73	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        655471 cleavage and polyadenylation specificity factor subunit 4-like	K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4 
E        660072 Cpsf4; cleavage and polyadenylation specific factor 4, 30kDa	K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4 
E        655606 pre-mRNA polyadenylation factor FIP1	K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 
E        657647 pre-mRNA 3' end processing protein WDR33	K15542 PFS2; polyadenylation factor subunit 2 
E        654994 WD repeat-containing protein 82	K14962 WDR82; COMPASS component SWD2 
E        656485 FK506-binding protein 59	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        103312533 serine/threonine-protein phosphatase PP1-alpha-like	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        103312848 serine/threonine-protein phosphatase PP1-beta catalytic subunit	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        100141788 serine/threonine-protein phosphatase alpha-2 isoform	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        657409 RNA polymerase II subunit A C-terminal domain phosphatase SSU72	K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16] 
D      Cleavage stimulation factor (CSTF) complex
E        656518 cleavage stimulation factor subunit 1	K14406 CSTF1; cleavage stimulation factor subunit 1 
E        659353 cleavage stimulation factor subunit 2 tau variant	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        661644 protein suppressor of forked	K14408 CSTF3; cleavage stimulation factor subunit 3 
E        103314929 symplekin	K06100 SYMPK; symplekin 
D      U7-dependent histone pre-mRNA processing factors
E        663178 small nuclear ribonucleoprotein-associated protein B	K11086 SNRPB; small nuclear ribonucleoprotein B and B' 
E        661326 small nuclear ribonucleoprotein Sm D3	K11088 SNRPD3; small nuclear ribonucleoprotein D3 
E        103312296 probable small nuclear ribonucleoprotein E	K11097 SNRPE; small nuclear ribonucleoprotein E 
E        658284 small nuclear ribonucleoprotein F	K11098 SNRPF; small nuclear ribonucleoprotein F 
E        656057 probable small nuclear ribonucleoprotein G	K11099 SNRPG; small nuclear ribonucleoprotein G 
E        103313703 U7 snRNA-associated Sm-like protein LSm10	K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10 
E        103315009 U7 snRNA-associated Sm-like protein LSm11	K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11 
E        659785 probable cleavage and polyadenylation specificity factor subunit 2	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        103314846 cleavage and polyadenylation specificity factor 73	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        659353 cleavage stimulation factor subunit 2 tau variant	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        103314929 symplekin	K06100 SYMPK; symplekin 
E        103314257 histone RNA hairpin-binding protein	K18710 SLBP; histone RNA hairpin-binding protein 
D      DRB sensitivity inducing factor (DSIF) complex
E        662060 transcription elongation factor SPT4	K15171 SUPT4H1; transcription elongation factor SPT4 
E        659727 transcription elongation factor SPT5	K15172 SUPT5H; transcription elongation factor SPT5 
D      N6-methyltransferase complex
E        656280 N6-adenosine-methyltransferase 70 kDa subunit	K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348] 
E        663857 methyltransferase-like protein 14 homolog	K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit 
E        655139 methyltransferase-like protein 4	K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72] 
E        661821 methyltransferase-like protein 16 homolog	K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346] 
E        663936 pre-mRNA-splicing regulator female-lethal(2)D	K22824 WTAP; pre-mRNA-splicing regulator WTAP 
E        100142261 protein virilizer	K22910 VIRMA; protein virilizer 
E        663518 putative RNA-binding protein 15B	K13190 RBM15; RNA-binding protein 15 
E        660353 RNA-binding protein 25	K22909 ZC3H13; zinc finger CCCH domain-containing protein 13 
E        660508 E3 ubiquitin-protein ligase Hakai	K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27] 
D      Poly(A) addition factors
E        103312455 poly(A) polymerase type 3	K14376 PAP; poly(A) polymerase [EC:2.7.7.19] 
E        662532 poly(A) RNA polymerase gld-2 homolog A	K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19] 
D      Negative regulators of mRNA 3' end processing
E        655134 RNA-binding protein 26	K13192 RBM26; RNA-binding protein 26 
E        656201 TAR DNA-binding protein 43	K23600 TARDBP; TAR DNA-binding protein 43 
C    Other processing factors
D      656744 DNA/RNA-binding protein KIN17	K13102 KIN; DNA/RNA-binding protein KIN17 
D      664064 methyltransferase-like protein 22	K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-] 
D      663557 uncharacterized LOC663557	K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19] 
D      664539 zinc finger CCCH domain-containing protein 14	K23038 ZC3H14; zinc finger CCCH domain-containing protein 14 
D      655511 serrate RNA effector molecule homolog	K27103 SRRT; serrate RNA effector molecule 
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
E        656135 Tsu; tsunagi	K12876 RBM8A; RNA-binding protein 8A 
E        656056 mago; mago nashi	K12877 MAGOH; protein mago nashi 
E        660256 THO complex subunit 4	K12881 THOC4; THO complex subunit 4 
E        662877 ATP-dependent RNA helicase WM6	K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7] 
E        664411 eukaryotic initiation factor 4A-III	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        659127 coiled-coil domain-containing protein 174	K25178 CCDC174; coiled-coil domain-containing protein 174 
E        664590 Btz; barentsz	K14323 CASC3; protein CASC3 
E        662665 histone deacetylase complex subunit SAP18	K14324 SAP18; histone deacetylase complex subunit SAP18 
E        664381 pinin	K13114 PNN; pinin 
E        658123 apoptotic chromatin condensation inducer	K12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus 
E        663923 RNA-binding protein with serine-rich domain 1	K14325 RNPS1; RNA-binding protein with serine-rich domain 1 
E        100142567 serine/arginine repetitive matrix protein 1	K13171 SRRM1; serine/arginine repetitive matrix protein 1 
D      TREX complex
E        658815 THO complex subunit 1	K12878 THOC1; THO complex subunit 1 
E        663288 THO complex subunit 2	K12879 THOC2; THO complex subunit 2 
E        656215 THO complex subunit 3	K12880 THOC3; THO complex subunit 3 
E        660256 THO complex subunit 4	K12881 THOC4; THO complex subunit 4 
E        661609 THO complex subunit 5 homolog	K13174 THOC5; THO complex subunit 5 
E        662625 THO complex subunit 6	K13175 THOC6; THO complex subunit 6 
E        660524 THO complex subunit 7 homolog	K13176 THOC7; THO complex subunit 7 
D      TREX-2 complex
E        100142368 PCI domain-containing protein 2	K23801 PCID2; nuclear mRNA export protein PCID2/THP1 
E        664162 probable 26S proteasome complex subunit sem1	K10881 SHFM1; 26 proteasome complex subunit DSS1 
E        657566 transcription and mRNA export factor ENY2	K11368 ENY2; enhancer of yellow 2 transcription factor 
D      Nuclear pore complex
E        655393 Mtor; nucleoprotein TPR	K09291 TPR; nucleoprotein TPR 
E        664096 Rae1; RAE1 RNA export 1 homolog	K14298 RAE1; mRNA export factor 
E        657583 protein SEC13 homolog	K14004 SEC13; protein transport protein SEC13 
E        100141734 nucleoporin Nup37	K14302 NUP37; nuclear pore complex protein Nup37 
E        660845 nuclear pore complex protein Nup85	K14304 NUP85; nuclear pore complex protein Nup85 
E        656380 nucleoporin Nup43	K14305 NUP43; nuclear pore complex protein Nup43 
E        664102 nuclear pore complex protein Nup50	K14295 NUP50; nuclear pore complex protein Nup50 
E        658410 probable nucleoporin Nup54	K14308 NUP54; nuclear pore complex protein Nup54 
E        661690 nuclear pore glycoprotein p62	K14306 NUP62; nuclear pore complex protein Nup62 
E        100141871 nuclear pore complex protein Nup88	K14318 NUP88; nuclear pore complex protein Nup88 
E        661634 nuclear pore complex protein Nup93	K14309 NUP93; nuclear pore complex protein Nup93 
E        656762 nuclear pore complex protein Nup98-Nup96	K14297 NUP98; nuclear pore complex protein Nup98-Nup96 
E        657989 nuclear pore complex protein Nup107	K14301 NUP107; nuclear pore complex protein Nup107 
E        664452 nuclear pore complex protein Nup133	K14300 NUP133; nuclear pore complex protein Nup133 
E        655828 uncharacterized LOC655828	K14311 NUP188; nuclear pore complex protein Nup188 
E        660867 nuclear pore complex protein Nup153	K14296 NUP153; nuclear pore complex protein Nup153 
E        657709 nuclear pore complex protein Nup155	K14312 NUP155; nuclear pore complex protein Nup155 
E        656625 nuclear pore complex protein Nup160 homolog	K14303 NUP160; nuclear pore complex protein Nup160 
E        660711 nucleoporin NUP53	K14313 NUP35; nuclear pore complex protein Nup53 
E        662841 nuclear pore complex protein Nup205	K14310 NUP205; nuclear pore complex protein Nup205 
E        658596 nuclear pore membrane glycoprotein 210	K14314 NUP210; nuclear pore complex protein Nup210 
E        654990 nuclear pore complex protein Nup214	K14317 NUP214; nuclear pore complex protein Nup214 
E        659014 hypothetical protein	K14316 POM121; nuclear pore complex protein Nup121 
E        659579 probable nucleoporin Nup58	K14307 NUPL1; nucleoporin p58/p45 
E        664038 nucleoporin-like protein 2	K14321 NUPL2; nucleoporin-like protein 2 
E        100141863 nucleoporin NDC1	K14315 NDC1; nucleoporin NDC1 
E        661803 nucleoporin SEH1	K14299 SEH1; nucleoporin SEH1 
E        655426 E3 SUMO-protein ligase RanBP2	K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-] 
E        658353 aladin	K14320 AAAS; aladin 
E        663768 nucleoporin GLE1	K18723 GLE1; nucleoporin GLE1 
E        103312682 nuclear RNA export factor 2	K14284 NXF; nuclear RNA export factor 
E        103312683 nuclear RNA export factor 1	K14284 NXF; nuclear RNA export factor 
E        656618 nuclear RNA export factor 1	K14284 NXF; nuclear RNA export factor 
E        657794 NTF2-related export protein	K14285 NXT1_2; NTF2-related export protein 1/2 
D      Ran-mediated transport factors
E        657695 GTP-binding nuclear protein Ran	K07936 RAN; GTP-binding nuclear protein Ran 
E        654968 acidic leucine-rich nuclear phosphoprotein 32 family member A	K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D 
E        659897 ELAV-like protein 4	K13208 ELAVL2_3_4; ELAV like protein 2/3/4 
E        656053 FAS-associated factor 2	K18726 FAF2; FAS-associated factor 2 
E        661187 TER94; transitional endoplasmic reticulum ATPase TER94	K13525 VCP; transitional endoplasmic reticulum ATPase 
E        662656 exportin-1	K14290 XPO1; exportin-1 
E        655656 exportin-7	K18460 XPO7; exportin-7 
E        659231 ran GTPase-activating protein 1	K14319 RANGAP1; Ran GTPase-activating protein 1 
D      eIF4F and regulatory proteins
E        662295 eIF-4E; eukaryotic initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        658700 eIF-4E; eukaryotic initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        100463502 eIF-4a; eukaryotic initiation factor 4a	K03257 EIF4A; translation initiation factor 4A 
E        656935 eukaryotic translation initiation factor 4 gamma 3	K03260 EIF4G; translation initiation factor 4G 
E        658277 eukaryotic translation initiation factor 4 gamma 2	K03260 EIF4G; translation initiation factor 4G 
E        655831 eukaryotic translation initiation factor 4B	K03258 EIF4B; translation initiation factor 4B 
E        660722 eukaryotic translation initiation factor 4H	K24086 EIF4H; translation initiation factor 4H 
E        663803 eukaryotic translation initiation factor 4E-binding protein 2	K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2 
E        658049 Eif4enif1; eukaryotic translation initiation factor 4E transporter	K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter 
E        664156 protein angel	K18729 ANGEL; protein angel 
E        657873 fragile X mental retardation syndrome-related protein 1	K15516 FMR; fragile X mental retardation protein 
E        656140 cytoplasmic FMR1-interacting protein	K05749 CYFIP; cytoplasmic FMR1 interacting protein 
E        100141744 gem-associated protein 5	K13133 GEMIN5; gem associated protein 5 
E        661956 orb; oo18 RNA-binding protein	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        657803 orb2; probable RNA-binding protein orb2	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        656268 belle; ATP-dependent RNA helicase belle	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        658036 PERQ amino acid-rich with GYF domain-containing protein CG11148	K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
E        657776 polyadenylate-binding protein 1	K13126 PABPC; polyadenylate-binding protein 
E        660632 polyadenylate-binding protein 4-like	K13126 PABPC; polyadenylate-binding protein 
E        103312241 polyadenylate-binding protein-interacting protein 1	K14322 PAIP1; polyadenylate-binding protein-interacting protein 1 
E        657145 polyadenylate-binding protein-interacting protein 2B	K27470 PAIP2; polyadenylate-binding protein-interacting protein 2 
E        659256 helicase SKI2W	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        655086 deformed epidermal autoregulatory factor 1	K23041 DEAF1; deformed epidermal autoregulatory factor 1 
E        658422 malignant T-cell-amplified sequence 1 homolog	K07575 MCTS; malignant T-cell-amplified sequence 
E        659937 density-regulated protein homolog	K24272 DENR; density-regulated protein 
D      APOBEC1-ACF complex
D      Other transport factors
E        663159 partner of Y14 and mago	K14294 WIBG; partner of Y14 and mago 
E        657465 heterogeneous nuclear ribonucleoprotein A1, A2/B1 homolog	K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
E        655156 heterogeneous nuclear ribonucleoprotein 27C	K14411 MSI; RNA-binding protein Musashi 
E        656824 RNA-binding protein Musashi homolog 2	K14411 MSI; RNA-binding protein Musashi 
E        656553 RNA-binding protein Musashi homolog Rbp6	K14411 MSI; RNA-binding protein Musashi 
E        657404 HBS1-like protein	K14416 HBS1; elongation factor 1 alpha-like protein 
E        655490 pelo; pelota	K06965 PELO; protein pelota 
E        664338 polyadenylate-binding protein 2	K14396 PABPN1; polyadenylate-binding protein 2 
E        662733 DEAD-box helicase Dbp80	K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7] 
E        656462 pre-mRNA-splicing factor SYF1	K12867 SYF1; pre-mRNA-splicing factor SYF1 
E        100301567 Sarnp; SAP domain containing ribonucleoprotein	K18732 SARNP; SAP domain-containing ribonucleoprotein 
E        658717 regulator of chromosome condensation	K11493 RCC1; regulator of chromosome condensation 
E        664329 la-related protein 6	K18733 LARP6; la-related protein 6 
E        662482 transcriptional activator protein Pur-alpha	K21772 PURA; transcriptional activator protein Pur-alpha 
E        657843 polymerase delta-interacting protein 3	K22414 POLDIP3; polymerase delta-interacting protein 3 
E        103312695 zinc finger CCCH domain-containing protein 11A	K22415 ZC3H11; zinc finger CCCH domain-containing protein 11 
E        661290 leukocyte receptor cluster member 8 homolog	K23802 LENG8; SAC3 family protein LENG8/THP3 
C    Surveillance factors
D      Surveillance complex
E        660337 eukaryotic peptide chain release factor subunit 1	K03265 ETF1; peptide chain release factor subunit 1 
E        657209 eukaryotic peptide chain release factor GTP-binding subunit ERF3A	K03267 ERF3; peptide chain release factor subunit 3 
E        662109 regulator of nonsense transcripts 1 homolog	K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] 
E        658027 regulator of nonsense transcripts 2	K14327 UPF2; regulator of nonsense transcripts 2 
E        663859 regulator of nonsense transcripts 3A	K14328 UPF3; regulator of nonsense transcripts 3 
D      Protein phosphatase 2A
E        662352 serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] 
E        656557 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform	K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A 
E        641602 Ppp2r1a; protein phosphatase 2, regulatory subunit A, alpha isoform	K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A 
E        659477 protein phosphatase PP2A 55 kDa regulatory subunit	K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B 
E        659659 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma	K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B'' 
E        658209 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta	K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B'' 
E        664455 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
E        659798 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
D      Other surveillance factors
E        658025 serine/threonine-protein kinase SMG1	K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1] 
E        100142092 protein SMG5	K11125 SMG5; protein SMG5 
E        663281 uncharacterized LOC663281	K11124 SMG6; protein SMG6 [EC:3.1.-.-] 
E        657474 protein SMG7	K14409 SMG7; protein SMG7 
E        663043 protein smg8	K18734 SMG8; protein SMG8 
E        660230 protein SMG9	K18735 SMG9; protein SMG9 
E        658036 PERQ amino acid-rich with GYF domain-containing protein CG11148	K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
E        662377 probable ATP-dependent RNA helicase DHX34	K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6] 
E        659196 GTP-binding protein 1	K24887 GTPBP1; GTP-binding protein 1 
C    Factors involved in mRNA localization
D      Cargo complex
E        659669 protein penguin	K14844 PUF6; pumilio homology domain family member 6 
E        663516 Myo5; myosin 5	K10357 MYO5; myosin V 
E        659533 BicD; bicaudal D	K18739 BICD; protein bicaudal D 
E        100141895 exonuclease 3'-5' domain-containing protein 1	K18740 EXD1; exonuclease 3'-5' domain-containing protein 1 
E        657496 egl; egalitarian	K18740 EXD1; exonuclease 3'-5' domain-containing protein 1 
D      Factors that have mRNA localization signals
E        659219 Arp1; actin related protein 1	K05692 ACTB_G1; actin beta/gamma 1 
E        654492 Doc; dorsocross	K10180 TBX6; T-box protein 6 
E        661436 enhancer of split mgamma protein	K09090 HESN; hairy and enhancer of split, invertebrate 
E        660626 H; hairy	K09090 HESN; hairy and enhancer of split, invertebrate 
E        656046 protein deadpan	K09090 HESN; hairy and enhancer of split, invertebrate 
E        661225 enhancer of split mgamma protein	K09090 HESN; hairy and enhancer of split, invertebrate 
D      Trans-acting binding proteins
E        660887 far upstream element-binding protein 1	K13210 FUBP; far upstream element-binding protein 
E        658093 elongation factor 1-alpha	K03231 EEF1A; elongation factor 1-alpha 
E        655495 Efa1; elongation factor 1-alpha	K03231 EEF1A; elongation factor 1-alpha 
E        656235 elongation factor 1-gamma	K03233 EEF1G; elongation factor 1-gamma 
E        103313144 HCLS1-associated protein X-1	K16220 HAX1; HCLS1-associated protein X-1 
E        664234 drongo; drongo protein	K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1 
E        657623 stau; staufen	K17597 STAU; double-stranded RNA-binding protein Staufen 
E        664406 double-stranded RNA-binding protein Staufen homolog 2	K17597 STAU; double-stranded RNA-binding protein Staufen 
E        654951 polypyrimidine tract-binding protein 1	K13218 PTBP1; polypyrimidine tract-binding protein 1 
E        663871 RNA-binding protein squid	K03102 SQD; squid 
E        661956 orb; oo18 RNA-binding protein	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        657803 orb2; probable RNA-binding protein orb2	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
D      Other mRNA localization factors
E        657873 fragile X mental retardation syndrome-related protein 1	K15516 FMR; fragile X mental retardation protein 
E        656140 cytoplasmic FMR1-interacting protein	K05749 CYFIP; cytoplasmic FMR1 interacting protein 
E        658107 poly(rC)-binding protein 3	K21444 PCBP3_4; poly(rC)-binding protein 3/4 
E        661585 caprin homolog	K18743 CAPRIN1; caprin-1 
E        660275 CUGBP Elav-like family member 1	K02177 BRU; bruno 
E        663640 exu; exuperantia	K18745 EXU; maternal protein exuperantia 
E        656063 Y-box factor homolog	K09276 YBX1; Y-box-binding protein 1 
E        654995 Sxl; sex lethal	K18747 SXL; protein sex-lethal 
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
E        663618 XRN1; 5'-3' exoribonuclease 1	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        659936 Ago-1; Argonaute-1	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        662044 Ago-2b; Argonaute-2b	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        658698 Ago-2a; Argonaute-2a	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        662295 eIF-4E; eukaryotic initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        658700 eIF-4E; eukaryotic initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        662109 regulator of nonsense transcripts 1 homolog	K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] 
E        656268 belle; ATP-dependent RNA helicase belle	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        663396 putative ATP-dependent RNA helicase me31b	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        655833 Mex-3; mex-3 protein	K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27] 
E        660798 protein LSM14 homolog B	K18749 LSM14; protein LSM14 
E        656063 Y-box factor homolog	K09276 YBX1; Y-box-binding protein 1 
E        655600 LIM domain-containing protein jub	K16682 AJUBA; LIM domain-containing protein 
E        663971 putative helicase mov-10-B.1	K18422 MOV10; helicase MOV-10 [EC:5.6.2.5] 
E        661251 putative helicase mov-10-B.1	K18422 MOV10; helicase MOV-10 [EC:5.6.2.5] 
E        107398242 proline-rich nuclear receptor coactivator 2-like	K18751 PNRC2; proline-rich nuclear receptor coactivator 2 
E        654903 TNPO1; transportin-1	K18752 TNPO1; transportin-1 
E        658025 serine/threonine-protein kinase SMG1	K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1] 
E        100142092 protein SMG5	K11125 SMG5; protein SMG5 
E        663281 uncharacterized LOC663281	K11124 SMG6; protein SMG6 [EC:3.1.-.-] 
E        657474 protein SMG7	K14409 SMG7; protein SMG7 
E        656846 protein TIS11	K15308 TTP; tristetraprolin 
E        664138 protein lin-28 homolog	K18754 LIN28; protein lin-28 
E        656784 huntingtin	K04533 HD; huntingtin 
E        663844 protein bicaudal C	K18756 BICC1; protein bicaudal C 
E        657465 heterogeneous nuclear ribonucleoprotein A1, A2/B1 homolog	K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
E        657232 cGMP-dependent protein kinase, isozyme 1	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        656552 Pka-C1; cAMP-dependent protein kinase 1	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        655660 cAMP-dependent protein kinase catalytic subunit beta	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        657260 la-related protein 1	K18757 LARP1; la-related protein 1 
E        660366 ataxin-2 homolog	K23625 ATXN2_2L; ataxin 2/2L 
D      P-body specific factors
E        656834 m7GpppN-mRNA hydrolase	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        659670 mRNA-decapping enzyme 1B	K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-] 
E        660013 U6 snRNA-associated Sm-like protein LSm1	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        655665 U6 snRNA-associated Sm-like protein LSm2	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        662059 U6 snRNA-associated Sm-like protein LSm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        664220 U6 snRNA-associated Sm-like protein LSm4	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        657007 U6 snRNA-associated Sm-like protein LSm5	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        663017 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        658224 U6 snRNA-associated Sm-like protein LSm7	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        660995 U6 snRNA-associated Sm-like protein LSm8	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
E        655195 kinesin light chain	K10407 KLC; kinesin light chain 
E        663516 Myo5; myosin 5	K10357 MYO5; myosin V 
E        656649 Tub84B; tubulin alpha 1-like protein	K07374 TUBA; tubulin alpha 
E        655491 tubulin alpha 1-like protein	K07374 TUBA; tubulin alpha 
E        662929 tubulin alpha-1 chain	K07374 TUBA; tubulin alpha 
E        656061 tubulin alpha chain	K07374 TUBA; tubulin alpha 
E        661956 orb; oo18 RNA-binding protein	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        657803 orb2; probable RNA-binding protein orb2	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        100141744 gem-associated protein 5	K13133 GEMIN5; gem associated protein 5 
E        661812 protein Gawky	K18412 TNRC6; trinucleotide repeat-containing gene 6 protein 
E        663739 CNOT1; CCR4-NOT transcription complex subunit 1	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        661220 regulator of gene activity	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        659082 CCR4-NOT transcription complex subunit 3	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        661055 uncharacterized LOC661055	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        663221 CCR4-NOT transcription complex subunit 6-like	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        664092 CCR4-NOT transcription complex subunit 7	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        657587 DIS3-like exonuclease 2	K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-] 
E        655299 PAB-dependent poly(A)-specific ribonuclease subunit PAN2	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        661077 PAB-dependent poly(A)-specific ribonuclease subunit PAN3	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
E        659063 protein Tob1	K14443 TOB; protein Tob/BTG 
E        655815 protein BTG1	K14443 TOB; protein Tob/BTG 
E        658049 Eif4enif1; eukaryotic translation initiation factor 4E transporter	K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter 
E        100142489 protein PAT1 homolog 1	K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 
E        663743 enhancer of mRNA-decapping protein 3	K12615 EDC3; enhancer of mRNA-decapping protein 3 
E        660021 enhancer of mRNA-decapping protein 4	K12616 EDC4; enhancer of mRNA-decapping protein 4 
E        658027 regulator of nonsense transcripts 2	K14327 UPF2; regulator of nonsense transcripts 2 
E        663859 regulator of nonsense transcripts 3A	K14328 UPF3; regulator of nonsense transcripts 3 
E        664018 E3 ubiquitin-protein ligase TRIM71	K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27] 
E        656122 RING finger protein nhl-1	K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27] 
E        658868 DNA-directed RNA polymerase II subunit RPB7	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
E        659651 YTH domain-containing family protein 3	K20102 YTHDF; YTH domain-containing family protein 
D      Stress granule specific factors
E        657616 nucleolysin TIA-1 isoform p40	K13201 TIA1; nucleolysin TIA-1/TIAR 
E        659024 nucleolysin TIAR	K13201 TIA1; nucleolysin TIA-1/TIAR 
E        657776 polyadenylate-binding protein 1	K13126 PABPC; polyadenylate-binding protein 
E        660632 polyadenylate-binding protein 4-like	K13126 PABPC; polyadenylate-binding protein 
E        657623 stau; staufen	K17597 STAU; double-stranded RNA-binding protein Staufen 
E        664406 double-stranded RNA-binding protein Staufen homolog 2	K17597 STAU; double-stranded RNA-binding protein Staufen 
E        657873 fragile X mental retardation syndrome-related protein 1	K15516 FMR; fragile X mental retardation protein 
E        664361 ras GTPase-activating protein-binding protein 2	K24983 G3BP2; Ras GTPase-activating protein-binding protein 2 
E        661048 eukaryotic translation initiation factor 2A	K15026 EIF2A; translation initiation factor 2A 
E        661605 eukaryotic translation initiation factor 3 subunit B	K03253 EIF3B; translation initiation factor 3 subunit B 
E        100463502 eIF-4a; eukaryotic initiation factor 4a	K03257 EIF4A; translation initiation factor 4A 
E        664411 eukaryotic initiation factor 4A-III	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        655831 eukaryotic translation initiation factor 4B	K03258 EIF4B; translation initiation factor 4B 
E        656935 eukaryotic translation initiation factor 4 gamma 3	K03260 EIF4G; translation initiation factor 4G 
E        658277 eukaryotic translation initiation factor 4 gamma 2	K03260 EIF4G; translation initiation factor 4G 
E        664211 ribosomal protein S6 kinase 2 beta	K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] 
E        662388 guanine nucleotide-binding protein subunit beta-like protein	K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein 
E        103312682 nuclear RNA export factor 2	K14284 NXF; nuclear RNA export factor 
E        103312683 nuclear RNA export factor 1	K14284 NXF; nuclear RNA export factor 
E        656618 nuclear RNA export factor 1	K14284 NXF; nuclear RNA export factor 
E        100141872 tudor domain-containing protein 3-like	K18404 TDRD3; tudor domain-containing protein 3 
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
E        659670 mRNA-decapping enzyme 1B	K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-] 
E        656834 m7GpppN-mRNA hydrolase	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        663396 putative ATP-dependent RNA helicase me31b	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        663743 enhancer of mRNA-decapping protein 3	K12615 EDC3; enhancer of mRNA-decapping protein 3 
E        660021 enhancer of mRNA-decapping protein 4	K12616 EDC4; enhancer of mRNA-decapping protein 4 
E        100142489 protein PAT1 homolog 1	K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 
D      Lsm complex
E        660013 U6 snRNA-associated Sm-like protein LSm1	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        655665 U6 snRNA-associated Sm-like protein LSm2	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        662059 U6 snRNA-associated Sm-like protein LSm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        664220 U6 snRNA-associated Sm-like protein LSm4	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        657007 U6 snRNA-associated Sm-like protein LSm5	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        663017 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        658224 U6 snRNA-associated Sm-like protein LSm7	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        660995 U6 snRNA-associated Sm-like protein LSm8	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
D      5' exonucleases
E        663618 XRN1; 5'-3' exoribonuclease 1	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        662556 5'-3' exoribonuclease 2 homolog	K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-] 
D      Other 5'-3' decay factors
E        658490 m7GpppX diphosphatase	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
E        656497 probable helicase with zinc finger domain	K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-] 
C    3'-5' decay
D      Core exosome factors
E        659788 exosome complex component CSL4	K07573 CSL4; exosome complex component CSL4 
E        657321 exosome complex component RRP4	K03679 RRP4; exosome complex component RRP4 
E        659032 exosome complex component RRP40	K03681 RRP40; exosome complex component RRP40 
E        664122 exosome complex component RRP41	K11600 RRP41; exosome complex component RRP41 
E        103313858 exosome complex component RRP46	K12590 RRP46; exosome complex component RRP46 
E        664182 exosome complex component MTR3	K12587 MTR3; exosome complex component MTR3 
E        655841 exosome complex component RRP42	K12589 RRP42; exosome complex component RRP42 
E        661417 exosome complex component RRP43	K12586 RRP43; exosome complex component RRP43 
E        662987 exosome complex component rrp45	K03678 RRP45; exosome complex component RRP45 
D      Exosome cofactors
E        655788 exosome complex exonuclease RRP44	K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] 
E        655198 exosome component 10	K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-] 
E        657430 exosome complex exonuclease RRP6	K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-] 
E        661062 nuclear nucleic acid-binding protein C1D	K12592 C1D; exosome complex protein LRP1 
E        657806 M-phase phosphoprotein 6	K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type 
D      TRAMP complex
E        103313558 non-canonical poly(A) RNA polymerase PAPD5	K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] 
E        658969 superkiller viralicidic activity 2-like 2	K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6] 
D      Ski complex
E        659256 helicase SKI2W	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        663570 tetratricopeptide repeat protein 37	K12600 SKI3; superkiller protein 3 
E        664186 WD repeat-containing protein 61	K12602 WDR61; WD repeat-containing protein 61 
D      Ccr4-NOT complex
E        663221 CCR4-NOT transcription complex subunit 6-like	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        663739 CNOT1; CCR4-NOT transcription complex subunit 1	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        661220 regulator of gene activity	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        659082 CCR4-NOT transcription complex subunit 3	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        661055 uncharacterized LOC661055	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        664092 CCR4-NOT transcription complex subunit 7	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        662846 cell differentiation protein RCD1 homolog	K12606 RCD1; CCR4-NOT transcription complex subunit 9 
E        662885 CCR4-NOT transcription complex subunit 10	K12607 CNOT10; CCR4-NOT transcription complex subunit 10 
D      Pan complex
E        655299 PAB-dependent poly(A)-specific ribonuclease subunit PAN2	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        661077 PAB-dependent poly(A)-specific ribonuclease subunit PAN3	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
D      Other 3'-5' decay factors
E        656287 poly(A)-specific ribonuclease PARN	K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4] 
E        659943 poly(A)-specific ribonuclease PARN-like domain-containing protein 1	K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4] 
E        664152 DHX36; ATP-dependent RNA helicase DHX36	K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6] 
E        659063 protein Tob1	K14443 TOB; protein Tob/BTG 
E        655815 protein BTG1	K14443 TOB; protein Tob/BTG 
E        663596 nocturnin	K18764 NOCT; nocturnin [EC:3.1.3.108] 
E        663485 Snp; Snipper	K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-] 
E        658490 m7GpppX diphosphatase	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
E        661460 2',5'-phosphodiesterase 12	K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-] 
E        661154 2',5'-phosphodiesterase 12	K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-] 
E        656497 probable helicase with zinc finger domain	K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-] 
E        658266 protein NRDE2 homolog	K26109 NRDE2; nuclear exosome regulator NRDE2 
E        658574 protein Smaug homolog 2	K27396 SMG; protein Smaug 
E        662711 uncharacterized LOC662711	K27498 FOCAD; focadhesin 
C    Other degradation factors
D      RNases
E        661984 probable ribonuclease ZC3H12B	K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-] 
#
A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        655800 ribonuclease 3	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
E        660205 oligoribonuclease, mitochondrial	K13288 orn; oligoribonuclease [EC:3.1.-.-] 
D      Helicases
D      Other RNA degradosome components
E        663391 enolase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        664159 enolase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        664168 enolase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        662995 polyribonucleotide nucleotidyltransferase 1, mitochondrial	K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 
E        658327 ATP-dependent 6-phosphofructokinase	K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] 
C    Other RNA degradation factors
D      Chaperones
E        664286 heat shock 70 kDa protein cognate 5	K04043 dnaK; molecular chaperone DnaK 
E        660294 60 kDa heat shock protein, mitochondrial	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
D      Others
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
E        657321 exosome complex component RRP4	K03679 RRP4; exosome complex component RRP4 
E        659788 exosome complex component CSL4	K07573 CSL4; exosome complex component CSL4 
D      Cofactors
E        664122 exosome complex component RRP41	K11600 RRP41; exosome complex component RRP41 
E        655841 exosome complex component RRP42	K12589 RRP42; exosome complex component RRP42 
D      Others
!
#<hr>
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#Last updated: April 25, 2024