KEGG Modules
Pathway modules
Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH: ame00010 ame01200 ame01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH: ame00010 ame01200 ame01230 ame01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH: ame00010 ame00020 ame01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH: ame00010 ame00020 ame00620 ame00785 ame01200 ame01210 ame01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH: ame00020 ame01200 ame01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH: ame00020 ame01200 ame01210 ame01230 ame01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH: ame00020 ame01200 ame01210 ame01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH: ame00030 ame01200 ame01100]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH: ame00030 ame01200 ame01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH: ame00030 ame01200 ame01230 ame01100]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH: ame00030 ame00230 ame01200 ame01230 ame01100]
Other carbohydrate metabolism
M00014 Glucuronate pathway (uronate pathway) [PATH: ame00040 ame01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH: ame00052 ame01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH: ame00500 ame01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH: ame00500 ame01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH: ame00520 ame01250 ame01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH: ame00520 ame00052 ame01250 ame01100]
M00892 UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc [PATH: ame00520 ame01250 ame01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH: ame00520 ame01250 ame01100]
M00012 Glyoxylate cycle [PATH: ame00630 ame01200 ame01100]
M00013 Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA [PATH: ame00410 ame00640 ame01200 ame01100]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH: ame00280 ame00630 ame00640 ame01200 ame01100]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH: ame00562 ame01100]
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH: ame00562 ame01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH: ame00562 ame01100]
Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH: ame00190 ame01100]
M00142 NADH:ubiquinone oxidoreductase, mitochondria [PATH: ame00190 ame01100]
M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH: ame00190 ame01100]
M00146 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH: ame00190 ame01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH: ame00190 ame01100]
M00150 Fumarate reductase, prokaryotes [PATH: ame00190 ame01100]
M00148 Succinate dehydrogenase (ubiquinone) [PATH: ame00190 ame01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH: ame00190 ame01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH: ame00190 ame01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH: ame00190]
M00417 Cytochrome o ubiquinol oxidase [PATH: ame00190 ame01100]
M00156 Cytochrome c oxidase, cbb3-type [PATH: ame00190 ame01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH: ame00190 ame01100]
M00158 F-type ATPase, eukaryotes [PATH: ame00190 ame01100]
M00159 V/A-type ATPase, prokaryotes [PATH: ame00190 ame01100]
M00160 V-type ATPase, eukaryotes [PATH: ame00190 ame01100]
Lipid metabolism
Fatty acid metabolism
Sterol biosynthesis
M00101 Cholesterol biosynthesis, FPP => cholesterol [PATH: ame00100 ame01100]
M00103 Cholecalciferol biosynthesis [PATH: ame00100 ame01100]
M00107 Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone [PATH: ame01100]
M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone [PATH: ame01100]
M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [PATH: ame01100]
M00976 C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone [PATH: ame01100]
Lipid metabolism
Nucleotide metabolism
Purine metabolism
Pyrimidine metabolism
Amino acid metabolism
Serine and threonine metabolism
Cysteine and methionine metabolism
Branched-chain amino acid metabolism
Lysine metabolism
Arginine and proline metabolism
Polyamine biosynthesis
Histidine metabolism
Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH: ame00400 ame01230 ame01100]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH: ame00400 ame01230 ame01100]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH: ame00400 ame01230 ame01100]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH: ame00400 ame01230 ame01100]
M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH: ame00350 ame01100]
M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH: ame00350 ame01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH: ame00350 ame01100]
M00037 Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin [PATH: ame00380 ame01100]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH: ame00380 ame01100]
Other amino acid metabolism
Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH: ame00730 ame01240 ame01100]
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH: ame00730 ame01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH: ame00740 ame01240 ame01100]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH: ame00750 ame01240 ame01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH: ame00760 ame01240 ame01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH: ame00770 ame01240 ame01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH: ame00780 ame01240 ame01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH: ame00785 ame01240 ame01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH: ame00785 ame01240 ame01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH: ame00785 ame01240 ame01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH: ame00790 ame00670 ame01240 ame01100]
M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4 [PATH: ame00790 ame01240 ame01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH: ame00790 ame01240 ame01100]
M00140 C1-unit interconversion, prokaryotes [PATH: ame00670 ame01240 ame01100]
M00141 C1-unit interconversion, eukaryotes [PATH: ame00670 ame01240 ame01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH: ame00860 ame01240 ame01100]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH: ame00860 ame01240 ame01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH: ame00860 ame01240 ame01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH: ame00130 ame01240 ame01100]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinol [PATH: ame00130 ame01240 ame01100]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH: ame00130 ame01240 ame01100]
Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Signature modules
Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation
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