KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:bai00010 bai01200 bai01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:bai00010 bai01200 bai01230 bai01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:bai00010 bai00020 bai01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:bai00010 bai00020 bai00620 bai00785 bai01200 bai01210 bai01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:bai00020 bai01200 bai01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:bai00020 bai01200 bai01210 bai01230 bai01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:bai00020 bai01200 bai01210 bai01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:bai00030 bai01200 bai01100 bai01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:bai00030 bai01200 bai01100 bai01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:bai00030 bai01200 bai01230 bai01100 bai01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:bai00030 bai00230 bai01200 bai01230 bai01100]

Other carbohydrate metabolism
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:bai00500 bai01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:bai00520 bai01250 bai01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:bai00520 bai01250 bai01100]
M00012 Glyoxylate cycle [PATH:bai00630 bai01200 bai01100 bai01110]

Energy metabolism
Carbon fixation
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:bai00430 bai00620 bai01200 bai01100 bai01120]

Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00151 Cytochrome bc1 complex respiratory unit [PATH:bai00190 bai01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:bai00190 bai01100]
M00416 Cytochrome aa3-600 menaquinol oxidase [PATH:bai00190 bai01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:bai00190 bai01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:bai00061 bai01212 bai01100]
M00083 Fatty acid biosynthesis, elongation [PATH:bai00061 bai01212 bai01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:bai00061 bai00071 bai01212 bai01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:bai00564 bai01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bai00230 bai01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bai00230 bai01232 bai01240 bai01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bai00230 bai01232 bai01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bai00230 bai00240 bai01232 bai01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:bai00240 bai01232 bai01240 bai01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:bai00240 bai01232 bai01100]

Amino acid metabolism
Serine and threonine metabolism
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:bai00260 bai01230 bai01100 bai01110]
M00621 Glycine cleavage system [PATH:bai00260 bai00630 bai00785 bai01200 bai01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:bai00270 bai00920 bai01200 bai01230 bai01100 bai01110]
M00609 Cysteine biosynthesis, methionine => cysteine [PATH:bai00270 bai01230 bai01100]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:bai00270 bai01230 bai01100]
M00034 Methionine salvage pathway [PATH:bai00270 bai01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:bai00290 bai00770 bai01210 bai01230 bai01100 bai01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:bai00290 bai01230 bai01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:bai00290 bai01210 bai01230 bai01100 bai01110]

Lysine metabolism
M00525 Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine [PATH:bai00300 bai01230 bai01100]
M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH:bai00300 bai01230 bai01100 bai01110]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:bai00220 bai01210 bai01230 bai01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:bai00220 bai01230 bai01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:bai00330 bai01230 bai01100]
M00970 Proline degradation, proline => glutamate [PATH:bai00330 bai01100]
M00972 Proline metabolism [PATH:bai00330 bai01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:bai00330 bai01100]
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:bai00330 bai01100]

Histidine metabolism
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:bai00340 bai01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:bai00400 bai01230 bai01100 bai01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:bai00400 bai01230 bai01100 bai01110]

Other amino acid metabolism
Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:bai00730 bai01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:bai00740 bai01240 bai01100 bai01110]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:bai00750 bai01240 bai01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:bai00760 bai01240 bai01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:bai00770 bai01240 bai01100 bai01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:bai00770 bai01240 bai01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:bai00780 bai01240 bai01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:bai00780 bai01240 bai01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:bai00785 bai01240 bai01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:bai00790 bai00670 bai01240 bai01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:bai00790 bai01240 bai01100]
M00140 C1-unit interconversion, prokaryotes [PATH:bai00670 bai01240 bai01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:bai00860 bai01240 bai01100 bai01110]
M00926 Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme [PATH:bai00860 bai01240 bai01100]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:bai00130 bai01240 bai01100 bai01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:bai00900 bai01100 bai01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:bai00900 bai01100 bai01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:bai00521 bai00523 bai00541 bai01250 bai01100 bai01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
M00859 Bacillus anthracis pathogenicity signature, anthrax toxin
M00860 Bacillus anthracis pathogenicity signature, polyglutamic acid capsule biosynthesis

Drug resistance
M00627 beta-Lactam resistance, Bla system [PATH:bai01501]

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity