KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:bbr00010 bbr01200 bbr01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:bbr00010 bbr01200 bbr01230 bbr01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:bbr00010 bbr00020 bbr01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:bbr00010 bbr00020 bbr00620 bbr00785 bbr01200 bbr01210 bbr01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:bbr00020 bbr01200 bbr01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:bbr00020 bbr01200 bbr01210 bbr01230 bbr01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:bbr00020 bbr01200 bbr01210 bbr01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:bbr00030 bbr01200 bbr01100 bbr01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:bbr00030 bbr01200 bbr01100 bbr01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:bbr00030 bbr01200 bbr01230 bbr01100 bbr01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:bbr00030 bbr00230 bbr01200 bbr01230 bbr01100]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:bbr00052 bbr01100]
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:bbr00052 bbr01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:bbr00500 bbr01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:bbr00500 bbr01100]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH:bbr00500 bbr01100 bbr01110]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:bbr00520 bbr01250 bbr01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:bbr00520 bbr00052 bbr01250 bbr01100]
M00892 UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc [PATH:bbr00520 bbr01250 bbr01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:bbr00520 bbr01250 bbr01100]
M00012 Glyoxylate cycle [PATH:bbr00630 bbr01200 bbr01100 bbr01110]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:bbr00280 bbr00630 bbr00640 bbr01200 bbr01100]

Energy metabolism
Carbon fixation
M00165 Reductive pentose phosphate cycle (Calvin cycle) [PATH:bbr01200 bbr01100 bbr01120]
M00168 CAM (Crassulacean acid metabolism), dark [PATH:bbr00620 bbr01200 bbr01100 bbr01120]
M00169 CAM (Crassulacean acid metabolism), light [PATH:bbr00620 bbr01200 bbr01100 bbr01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:bbr00430 bbr00620 bbr01200 bbr01100 bbr01120]

Methane metabolism
Nitrogen metabolism
M00175 Nitrogen fixation, nitrogen => ammonia [PATH:bbr00910 bbr01100 bbr01120]
M00531 Assimilatory nitrate reduction, nitrate => ammonia [PATH:bbr00910 bbr01100 bbr01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:bbr00920 bbr01100 bbr01120]
M00595 Thiosulfate oxidation by SOX complex, thiosulfate => sulfate [PATH:bbr00920 bbr01100 bbr01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:bbr00190 bbr01100]
M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:bbr00190 bbr01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:bbr00190 bbr01100]
M00150 Fumarate reductase, prokaryotes [PATH:bbr00190 bbr01100]
M00148 Succinate dehydrogenase (ubiquinone) [PATH:bbr00190 bbr01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:bbr00190 bbr01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:bbr00190 bbr01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:bbr00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:bbr00190 bbr01100]
M00156 Cytochrome c oxidase, cbb3-type [PATH:bbr00190 bbr01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:bbr00190 bbr01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:bbr00061 bbr01212 bbr01100]
M00083 Fatty acid biosynthesis, elongation [PATH:bbr00061 bbr01212 bbr01100]
M00874 Fatty acid biosynthesis in mitochondria, fungi [PATH:bbr00061 bbr01212 bbr01100]
M00415 Fatty acid elongation in endoplasmic reticulum [PATH:bbr01040 bbr01212 bbr01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:bbr00061 bbr00071 bbr01212 bbr01100]
M00087 beta-Oxidation [PATH:bbr00071 bbr01212 bbr01100]

Sterol biosynthesis
Lipid metabolism
M00098 Acylglycerol degradation [PATH:bbr00561 bbr01100]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:bbr00564 bbr01100]
M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:bbr00564 bbr01100]
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:bbr00564 bbr01100]
M00094 Ceramide biosynthesis [PATH:bbr01100]
M00100 Sphingosine degradation [PATH:bbr01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bbr00230 bbr01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bbr00230 bbr01232 bbr01240 bbr01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bbr00230 bbr01232 bbr01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bbr00230 bbr00240 bbr01232 bbr01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:bbr00230 bbr01232 bbr01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:bbr00240 bbr01240 bbr01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:bbr00240 bbr01232 bbr01240 bbr01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:bbr00240 bbr01232 bbr01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:bbr00260 bbr00680 bbr01200 bbr01230 bbr01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:bbr00260 bbr01230 bbr01100 bbr01110]
M00621 Glycine cleavage system [PATH:bbr00260 bbr00630 bbr00785 bbr01200 bbr01100]
M00033 Ectoine biosynthesis, aspartate => ectoine [PATH:bbr00260 bbr01210 bbr01230 bbr01100 bbr01120]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:bbr00270 bbr00920 bbr01200 bbr01230 bbr01100 bbr01110]
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:bbr00260 bbr00270 bbr01230 bbr01100]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:bbr00270 bbr01230 bbr01100]
M00034 Methionine salvage pathway [PATH:bbr00270 bbr01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:bbr00290 bbr00770 bbr01210 bbr01230 bbr01100 bbr01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:bbr00290 bbr01230 bbr01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:bbr00290 bbr01210 bbr01230 bbr01100 bbr01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:bbr00280 bbr01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:bbr00300 bbr01230 bbr01100]
M00030 Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine [PATH:bbr00300 bbr01230 bbr01100]
M00433 Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate [PATH:bbr00300 bbr01210 bbr01230 bbr01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:bbr00220 bbr01210 bbr01230 bbr01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:bbr00220 bbr01230 bbr01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:bbr00330 bbr01230 bbr01100]
M00970 Proline degradation, proline => glutamate [PATH:bbr00330 bbr01100]
M00972 Proline metabolism [PATH:bbr00330 bbr01100]

Polyamine biosynthesis
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:bbr00330 bbr01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:bbr00340 bbr01230 bbr01100 bbr01110]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:bbr00400 bbr01230 bbr01100 bbr01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:bbr00400 bbr01230 bbr01100 bbr01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:bbr00400 bbr01230 bbr01100 bbr01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:bbr00400 bbr01230 bbr01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:bbr00350 bbr01100]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:bbr00350 bbr01220 bbr01100 bbr01120]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:bbr00250 bbr00650 bbr01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:bbr00480 bbr01240 bbr01100]

Glycan metabolism
Glycan biosynthesis
M00055 N-glycan precursor biosynthesis [PATH:bbr01100]
M00072 N-glycosylation by oligosaccharyltransferase [PATH:bbr01100]

Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-KDO biosynthesis [PATH:bbr00540 bbr01250 bbr01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:bbr00540 bbr01250 bbr01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00911 Riboflavin biosynthesis, fungi, GTP => riboflavin/FMN/FAD [PATH:bbr00740 bbr01240 bbr01100]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:bbr00750 bbr01240 bbr01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:bbr00760 bbr01240 bbr01100]
M00912 NAD biosynthesis, tryptophan => quinolinate => NAD [PATH:bbr00380 bbr00760 bbr01240 bbr01100]
M00622 Nicotinate degradation, nicotinate => fumarate [PATH:bbr00760 bbr01100 bbr01120]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:bbr00770 bbr01240 bbr01100 bbr01110]
M00913 Pantothenate biosynthesis, 2-oxoisovalerate/spermine => pantothenate [PATH:bbr00770 bbr01240 bbr01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:bbr00770 bbr01240 bbr01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:bbr00780 bbr01240 bbr01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:bbr00780 bbr01240 bbr01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:bbr00785 bbr01240 bbr01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH:bbr00785 bbr01240 bbr01100]
M00884 Lipoic acid biosynthesis, octanoyl-CoA => dihydrolipoyl-E2 [PATH:bbr00785 bbr01240 bbr01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:bbr00790 bbr00670 bbr01240 bbr01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:bbr00790 bbr01240 bbr01100]
M00141 C1-unit interconversion, eukaryotes [PATH:bbr00670 bbr01240 bbr01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:bbr00860 bbr01240 bbr01100 bbr01110]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:bbr00860 bbr01240 bbr01100 bbr01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:bbr00860 bbr01240 bbr01100 bbr01110]
M00925 Cobalamin biosynthesis, aerobic, uroporphyrinogen III => precorrin 2 => cobyrinate a,c-diamide [PATH:bbr00860 bbr01240 bbr01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:bbr00860 bbr01240 bbr01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:bbr00130 bbr01240 bbr01100 bbr01110]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinol [PATH:bbr00130 bbr01240 bbr01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00095 C5 isoprenoid biosynthesis, mevalonate pathway [PATH:bbr00900 bbr01100 bbr01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:bbr00900 bbr01100 bbr01110]
M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes [PATH:bbr00900 bbr01100 bbr01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:bbr00521 bbr00523 bbr00541 bbr01250 bbr01100 bbr01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation
M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH:bbr00362 bbr01220 bbr01100 bbr01120]
M00623 Phthalate degradation, phthalate => protocatechuate [PATH:bbr00624 bbr01220 bbr01100 bbr01120]

Gene set
Pathogenicity
M00575 Pertussis pathogenicity signature, T1SS [PATH:bbr05133]
M00574 Pertussis pathogenicity signature, pertussis toxin [PATH:bbr05133]

Drug resistance
M00698 Multidrug resistance, efflux pump BpeEF-OprC

Plant pathogenicity
Symbiosis
M00664 Nodulation

Module set
Metabolic capacity
M00615 Nitrate assimilation
M00616 Sulfate-sulfur assimilation