KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:bcx00010 bcx01200 bcx01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:bcx00010 bcx01200 bcx01230 bcx01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:bcx00010 bcx00020 bcx01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:bcx00010 bcx00020 bcx00620 bcx00785 bcx01200 bcx01210 bcx01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:bcx00020 bcx01200 bcx01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:bcx00020 bcx01200 bcx01210 bcx01230 bcx01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:bcx00020 bcx01200 bcx01210 bcx01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:bcx00030 bcx01200 bcx01100 bcx01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:bcx00030 bcx01200 bcx01100 bcx01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:bcx00030 bcx01200 bcx01230 bcx01100 bcx01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:bcx00030 bcx00230 bcx01200 bcx01230 bcx01100]

Other carbohydrate metabolism
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:bcx00500 bcx01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:bcx00520 bcx01250 bcx01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:bcx00520 bcx01250 bcx01100]
M00012 Glyoxylate cycle [PATH:bcx00630 bcx01200 bcx01100 bcx01110]

Energy metabolism
Carbon fixation
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:bcx00430 bcx00620 bcx01200 bcx01100 bcx01120]

Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00151 Cytochrome bc1 complex respiratory unit [PATH:bcx00190 bcx01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:bcx00190 bcx01100]
M00416 Cytochrome aa3-600 menaquinol oxidase [PATH:bcx00190 bcx01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:bcx00190 bcx01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:bcx00061 bcx01212 bcx01100]
M00083 Fatty acid biosynthesis, elongation [PATH:bcx00061 bcx01212 bcx01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:bcx00061 bcx00071 bcx01212 bcx01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:bcx00564 bcx01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bcx00230 bcx01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bcx00230 bcx01232 bcx01240 bcx01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bcx00230 bcx01232 bcx01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bcx00230 bcx00240 bcx01232 bcx01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:bcx00240 bcx01232 bcx01240 bcx01100]

Amino acid metabolism
Serine and threonine metabolism
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:bcx00260 bcx01230 bcx01100 bcx01110]
M00621 Glycine cleavage system [PATH:bcx00260 bcx00630 bcx00785 bcx01200 bcx01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:bcx00270 bcx00920 bcx01200 bcx01230 bcx01100 bcx01110]
M00609 Cysteine biosynthesis, methionine => cysteine [PATH:bcx00270 bcx01230 bcx01100]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:bcx00270 bcx01230 bcx01100]
M00034 Methionine salvage pathway [PATH:bcx00270 bcx01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:bcx00290 bcx00770 bcx01210 bcx01230 bcx01100 bcx01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:bcx00290 bcx01230 bcx01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:bcx00290 bcx01210 bcx01230 bcx01100 bcx01110]

Lysine metabolism
M00525 Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine [PATH:bcx00300 bcx01230 bcx01100]
M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH:bcx00300 bcx01230 bcx01100 bcx01110]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:bcx00220 bcx01210 bcx01230 bcx01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:bcx00220 bcx01230 bcx01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:bcx00330 bcx01230 bcx01100]
M00970 Proline degradation, proline => glutamate [PATH:bcx00330 bcx01100]
M00972 Proline metabolism [PATH:bcx00330 bcx01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:bcx00330 bcx01100]
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:bcx00330 bcx01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:bcx00340 bcx01230 bcx01100 bcx01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:bcx00340 bcx01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:bcx00400 bcx01230 bcx01100 bcx01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:bcx00400 bcx01230 bcx01100 bcx01110]

Other amino acid metabolism
Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:bcx00730 bcx01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:bcx00740 bcx01240 bcx01100 bcx01110]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:bcx00750 bcx01240 bcx01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:bcx00770 bcx01240 bcx01100 bcx01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:bcx00770 bcx01240 bcx01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:bcx00780 bcx01240 bcx01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:bcx00780 bcx01240 bcx01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:bcx00785 bcx01240 bcx01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:bcx00790 bcx00670 bcx01240 bcx01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:bcx00790 bcx01240 bcx01100]
M00140 C1-unit interconversion, prokaryotes [PATH:bcx00670 bcx01240 bcx01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:bcx00860 bcx01240 bcx01100 bcx01110]
M00926 Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme [PATH:bcx00860 bcx01240 bcx01100]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:bcx00130 bcx01240 bcx01100 bcx01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:bcx00900 bcx01100 bcx01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:bcx00900 bcx01100 bcx01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:bcx00521 bcx00523 bcx00541 bcx01250 bcx01100 bcx01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
M00877 Kanosamine biosynthesis, glucose 6-phosphate => kanosamine [PATH:bcx00998 bcx01100 bcx01110]

Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation
M00569 Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA [PATH:bcx00362 bcx00622 bcx01220 bcx01100 bcx01120]

Gene set
Pathogenicity
M00859 Bacillus anthracis pathogenicity signature, anthrax toxin

Drug resistance
M00627 beta-Lactam resistance, Bla system [PATH:bcx01501]
M00700 Multidrug resistance, efflux pump AbcA

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity