KEGG Modules
Pathway modules
Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH: ppe00010 ppe01200 ppe01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH: ppe00010 ppe01200 ppe01230 ppe01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH: ppe00010 ppe00020 ppe01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH: ppe00010 ppe00020 ppe00620 ppe00785 ppe01200 ppe01210 ppe01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH: ppe00020 ppe01200 ppe01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH: ppe00020 ppe01200 ppe01210 ppe01230 ppe01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH: ppe00020 ppe01200 ppe01210 ppe01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH: ppe00030 ppe01200 ppe01100 ppe01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH: ppe00030 ppe01200 ppe01100 ppe01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH: ppe00030 ppe01200 ppe01230 ppe01100 ppe01120]
M00580 Pentose phosphate pathway, archaea, fructose 6P => ribose 5P [PATH: ppe00030 ppe01200 ppe01230 ppe01100 ppe01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH: ppe00030 ppe00230 ppe01200 ppe01230 ppe01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH: ppe00030 ppe01200 ppe01100 ppe01120]
Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:ppe00040 ppe00030 ppe01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:ppe00040 ppe00030 ppe01100]
M00081 Pectin degradation [PATH:ppe00040 ppe01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:ppe00052 ppe01100]
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:ppe00052 ppe01100]
M00114 Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:ppe00051 ppe01240 ppe01100 ppe01110]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:ppe00500 ppe01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:ppe00500 ppe01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:ppe00520 ppe01250 ppe01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:ppe00520 ppe00052 ppe01250 ppe01100]
M00892 UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc [PATH:ppe00520 ppe01250 ppe01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:ppe00520 ppe01250 ppe01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:ppe00520 ppe01100]
M00012 Glyoxylate cycle [PATH:ppe00630 ppe01200 ppe01100 ppe01110]
M00532 Photorespiration [PATH:ppe00630 ppe01200 ppe01100 ppe01110]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:ppe00280 ppe00630 ppe00640 ppe01200 ppe01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:ppe00562 ppe01100]
Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
Lipid metabolism
Fatty acid metabolism
Sterol biosynthesis
Lipid metabolism
Nucleotide metabolism
Purine metabolism
Pyrimidine metabolism
Amino acid metabolism
Serine and threonine metabolism
Cysteine and methionine metabolism
Branched-chain amino acid metabolism
Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH: ppe00300 ppe01230 ppe01100]
M00525 Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine [PATH: ppe00300 ppe01230 ppe01100]
M00526 Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine [PATH: ppe00300 ppe01230 ppe01100]
M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH: ppe00300 ppe01230 ppe01100 ppe01110]
M00030 Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine [PATH: ppe00300 ppe01230 ppe01100]
M00433 Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate [PATH: ppe00300 ppe01210 ppe01230 ppe01100]
M00957 Lysine degradation, bacteria, L-lysine => glutarate => succinate/acetyl-CoA [PATH: ppe00310 ppe01100 ppe01120]
Arginine and proline metabolism
Polyamine biosynthesis
Histidine metabolism
Aromatic amino acid metabolism
Other amino acid metabolism
Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH: ppe00730 ppe01240 ppe01100]
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH: ppe00730 ppe01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH: ppe00740 ppe01240 ppe01100 ppe01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH: ppe01240 ppe01100]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH: ppe01240 ppe01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH: ppe00760 ppe01240 ppe01100]
M00912 NAD biosynthesis, tryptophan => quinolinate => NAD [PATH: ppe00760 ppe01240 ppe01100]
M00622 Nicotinate degradation, nicotinate => fumarate [PATH: ppe00760 ppe01100 ppe01120]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH: ppe00770 ppe01240 ppe01100 ppe01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH: ppe00770 ppe01240 ppe01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH: ppe00780 ppe01240 ppe01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH: ppe00780 ppe01240 ppe01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH: ppe00785 ppe01240 ppe01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH: ppe00785 ppe01240 ppe01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH: ppe00790 ppe00670 ppe01240 ppe01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH: ppe00790 ppe01240 ppe01100]
M00140 C1-unit interconversion, prokaryotes [PATH: ppe00670 ppe01240 ppe01100]
M00141 C1-unit interconversion, eukaryotes [PATH: ppe00670 ppe01240 ppe01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH: ppe01240 ppe01100 ppe01110]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH: ppe01240 ppe01100 ppe01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH: ppe01240 ppe01100 ppe01110]
M00926 Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme [PATH: ppe01240 ppe01100]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH: ppe01240 ppe01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH: ppe01240 ppe01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH: ppe00130 ppe01240 ppe01100 ppe01110]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinol [PATH: ppe00130 ppe01240 ppe01100]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH: ppe00130 ppe01240 ppe01100 ppe01110]
M00932 Phylloquinone biosynthesis, chorismate (+ phytyl-PP) => phylloquinol [PATH: ppe00130 ppe01240 ppe01100 ppe01110]
M00112 Tocopherol/tocotorienol biosynthesis, homogentisate + phytyl/geranylgeranyl-PP => tocopherol/tocotorienol [PATH: ppe00130 ppe01240 ppe01100 ppe01110]
M00933 Plastoquinone biosynthesis, homogentisate + solanesyl-PP => plastoquinol [PATH: ppe00130 ppe01240 ppe01100 ppe01110]
Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Signature modules
Gene set
Pathogenicity
Drug resistance
M00627 beta-Lactam resistance, Bla system [PATH:ppe01501]
M00745 Imipenem resistance, repression of porin OprD
M00641 Multidrug resistance, efflux pump MexEF-OprN
M00642 Multidrug resistance, efflux pump MexJK-OprM
M00705 Multidrug resistance, efflux pump MepA
Plant pathogenicity
Symbiosis
Module set
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