KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:sau00010 sau01200 sau01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:sau00010 sau01200 sau01230 sau01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:sau00010 sau00020 sau01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:sau00010 sau00020 sau00620 sau00785 sau01200 sau01210 sau01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:sau00020 sau01200 sau01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:sau00020 sau01200 sau01210 sau01230 sau01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:sau00020 sau01200 sau01210 sau01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:sau00030 sau01200 sau01100 sau01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:sau00030 sau01200 sau01100 sau01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:sau00030 sau01200 sau01230 sau01100 sau01120]
M00580 Pentose phosphate pathway, archaea, fructose 6P => ribose 5P [PATH:sau00030 sau01200 sau01230 sau01100 sau01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:sau00030 sau00230 sau01200 sau01230 sau01100]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:sau00052 sau01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:sau00500 sau01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:sau00500 sau01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:sau00520 sau01250 sau01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:sau00520 sau00052 sau01250 sau01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:sau00520 sau01250 sau01100]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sau00280 sau00630 sau00640 sau01200 sau01100]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:sau00620 sau01200 sau01100 sau01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:sau00430 sau00620 sau01200 sau01100 sau01120]

Methane metabolism
M00345 Formaldehyde assimilation, ribulose monophosphate pathway [PATH:sau00030 sau00680 sau01200 sau01230 sau01100 sau01120]

Nitrogen metabolism
Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:sau00920 sau01100 sau01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:sau00190 sau01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:sau00190 sau01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:sau00190 sau01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:sau00190 sau01100]
M00416 Cytochrome aa3-600 menaquinol oxidase [PATH:sau00190 sau01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:sau00190 sau01100]
M00159 V/A-type ATPase, prokaryotes [PATH:sau00190 sau01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:sau00061 sau01212 sau01100]
M00083 Fatty acid biosynthesis, elongation [PATH:sau00061 sau01212 sau01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:sau00061 sau00071 sau01212 sau01100]
M00087 beta-Oxidation [PATH:sau00071 sau01212 sau01100]

Sterol biosynthesis
Lipid metabolism
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:sau00564 sau01100]
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:sau00564 sau01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sau00230 sau01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sau00230 sau01232 sau01240 sau01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sau00230 sau01232 sau01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sau00230 sau00240 sau01232 sau01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:sau00230 sau01232 sau01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:sau00230 sau01232 sau01100]
M00546 Purine degradation, xanthine => urea [PATH:sau00230 sau01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:sau00240 sau01232 sau01240 sau01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:sau00240 sau01232 sau01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:sau00260 sau00680 sau01200 sau01230 sau01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:sau00260 sau01230 sau01100 sau01110]
M00621 Glycine cleavage system [PATH:sau00260 sau00630 sau00785 sau01200 sau01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:sau00260 sau01100]
M00033 Ectoine biosynthesis, aspartate => ectoine [PATH:sau00260 sau01210 sau01230 sau01100 sau01120]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:sau00270 sau00920 sau01200 sau01230 sau01100 sau01110]
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:sau00260 sau00270 sau01230 sau01100]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:sau00270 sau01230 sau01100]
M00035 Methionine degradation [PATH:sau00270 sau01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:sau00290 sau00770 sau01210 sau01230 sau01100 sau01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:sau00290 sau01230 sau01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:sau00290 sau01210 sau01230 sau01100 sau01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:sau00300 sau01230 sau01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:sau00220 sau01210 sau01230 sau01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:sau00220 sau01230 sau01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:sau00330 sau01230 sau01100]
M00970 Proline degradation, proline => glutamate [PATH:sau00330 sau01100]
M00972 Proline metabolism [PATH:sau00330 sau01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:sau00340 sau01230 sau01100 sau01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:sau00340 sau01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:sau00400 sau01230 sau01100 sau01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:sau00400 sau01230 sau01100 sau01110]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:sau00250 sau00650 sau01100]
M00949 Staphylopine biosynthesis, L-histidine => staphylopine [PATH:sau00470 sau01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:sau00730 sau01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:sau00740 sau01240 sau01100 sau01110]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:sau00750 sau01240 sau01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:sau00760 sau01240 sau01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:sau00770 sau01240 sau01100 sau01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:sau00770 sau01240 sau01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:sau00780 sau01240 sau01100]
M00577 Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin [PATH:sau00780 sau01240 sau01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:sau00785 sau01240 sau01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:sau00785 sau01240 sau01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:sau00790 sau00670 sau01240 sau01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:sau00790 sau01240 sau01100]
M00140 C1-unit interconversion, prokaryotes [PATH:sau00670 sau01240 sau01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:sau00860 sau01240 sau01100 sau01110]
M00926 Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme [PATH:sau00860 sau01240 sau01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:sau00860 sau01240 sau01100]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:sau00130 sau01240 sau01100 sau01110]
M00930 Menaquinone biosynthesis, futalosine pathway [PATH:sau00130 sau01240 sau01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:sau00900 sau01100 sau01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:sau00900 sau01100 sau01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:sau00521 sau00541 sau01250 sau01100 sau01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
M00876 Staphyloferrin A biosynthesis, L-ornithine => staphyloferrin A [PATH:sau00997 sau01100 sau01110]
M00875 Staphyloferrin B biosynthesis, L-serine => staphyloferrin B [PATH:sau00997 sau01100 sau01110]

Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00625 Methicillin resistance [PATH:sau01501]
M00627 beta-Lactam resistance, Bla system [PATH:sau01501]
M00704 Tetracycline resistance, efflux pump Tet38
M00725 Cationic antimicrobial peptide (CAMP) resistance, dltABCD operon [PATH:sau01503]
M00726 Cationic antimicrobial peptide (CAMP) resistance, lysyl-phosphatidylglycerol (L-PG) synthase MprF [PATH:sau01503]
M00730 Cationic antimicrobial peptide (CAMP) resistance, VraFG transporter [PATH:sau01503]
M00700 Multidrug resistance, efflux pump AbcA
M00702 Multidrug resistance, efflux pump NorB
M00714 Multidrug resistance, efflux pump QacA
M00705 Multidrug resistance, efflux pump MepA

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity