KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:sei00010 sei01200 sei01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:sei00010 sei01200 sei01230 sei01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:sei00010 sei00020 sei01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:sei00010 sei00020 sei00620 sei00785 sei01200 sei01210 sei01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:sei00020 sei01200 sei01210 sei01230 sei01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:sei00030 sei01200 sei01100 sei01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:sei00030 sei01200 sei01100 sei01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:sei00030 sei01200 sei01230 sei01100 sei01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:sei00030 sei00230 sei01200 sei01230 sei01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:sei00030 sei01200 sei01100 sei01120]

Other carbohydrate metabolism
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:sei00040 sei00030 sei01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:sei00052 sei01100]
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:sei00052 sei01100]
M00550 Ascorbate degradation, ascorbate => D-xylulose-5P [PATH:sei00053 sei01100 sei01120]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:sei00500 sei01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:sei00500 sei01100]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH:sei00500 sei01100 sei01110]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:sei00520 sei01250 sei01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:sei00520 sei00052 sei01250 sei01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:sei00520 sei01250 sei01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:sei00520 sei01100]
M00012 Glyoxylate cycle [PATH:sei00630 sei01200 sei01100 sei01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:sei00620 sei01200 sei01100 sei01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:sei00430 sei00620 sei01200 sei01100 sei01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:sei00910 sei01100 sei01120]

Sulfur metabolism
Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:sei00190 sei01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:sei00190 sei01100]
M00150 Fumarate reductase, prokaryotes [PATH:sei00190 sei01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:sei00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:sei00190 sei01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:sei00190 sei01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:sei00061 sei01212 sei01100]
M00083 Fatty acid biosynthesis, elongation [PATH:sei00061 sei01212 sei01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:sei00061 sei00071 sei01212 sei01100]
M00087 beta-Oxidation [PATH:sei00071 sei01212 sei01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:sei00564 sei01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sei00230 sei01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sei00230 sei01232 sei01240 sei01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sei00230 sei01232 sei01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sei00230 sei00240 sei01232 sei01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:sei00240 sei01240 sei01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:sei00240 sei01232 sei01240 sei01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:sei00240 sei01232 sei01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:sei00260 sei00680 sei01200 sei01230 sei01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:sei00260 sei01230 sei01100 sei01110]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:sei00270 sei00920 sei01200 sei01230 sei01100 sei01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:sei00270 sei01230 sei01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:sei00290 sei00770 sei01210 sei01230 sei01100 sei01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:sei00290 sei01230 sei01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:sei00290 sei01210 sei01230 sei01100 sei01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:sei00300 sei01230 sei01100]
M00956 Lysine degradation, bacteria, L-lysine => succinate [PATH:sei00310 sei01100 sei01120]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:sei00220 sei01210 sei01230 sei01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:sei00220 sei01230 sei01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:sei00330 sei01230 sei01100]
M00970 Proline degradation, proline => glutamate [PATH:sei00330 sei01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:sei00330 sei01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:sei00340 sei01230 sei01100 sei01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:sei00340 sei01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:sei00400 sei01230 sei01100 sei01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:sei00400 sei01230 sei01100 sei01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:sei00400 sei01230 sei01100 sei01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:sei00400 sei01230 sei01100]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:sei00350 sei01220 sei01100 sei01120]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:sei00480 sei01240 sei01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:sei00540 sei01100]
M00063 CMP-KDO biosynthesis [PATH:sei00540 sei01250 sei01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:sei00540 sei01250 sei01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:sei00730 sei01240 sei01100]
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:sei00730 sei01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:sei00740 sei01240 sei01100 sei01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:sei00750 sei01240 sei01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:sei00760 sei01240 sei01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:sei00770 sei01240 sei01100 sei01110]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:sei00780 sei01240 sei01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:sei00780 sei01240 sei01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:sei00785 sei01240 sei01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:sei00790 sei00670 sei01240 sei01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:sei00790 sei01240 sei01100]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH:sei00860 sei01240 sei01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:sei00860 sei01240 sei01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:sei00130 sei01240 sei01100 sei01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:sei00130 sei01240 sei01100 sei01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:sei00900 sei01100 sei01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:sei00900 sei01100 sei01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
M00857 Salmonella enterica pathogenicity signature, Vi antigen

Drug resistance
M00744 Cationic antimicrobial peptide (CAMP) resistance, protease PgtE
M00696 Multidrug resistance, efflux pump AcrEF-TolC

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity