KEGG Modules
Pathway modules
Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH: sme00010 sme01200 sme01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH: sme00010 sme01200 sme01230 sme01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH: sme00010 sme00020 sme01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH: sme00010 sme00020 sme00620 sme00785 sme01200 sme01210 sme01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH: sme00020 sme01200 sme01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH: sme00020 sme01200 sme01210 sme01230 sme01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH: sme00020 sme01200 sme01210 sme01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH: sme00030 sme01200 sme01100 sme01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH: sme00030 sme01200 sme01100 sme01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH: sme00030 sme01200 sme01230 sme01100 sme01120]
M00580 Pentose phosphate pathway, archaea, fructose 6P => ribose 5P [PATH: sme00030 sme01200 sme01230 sme01100 sme01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH: sme00030 sme00230 sme01200 sme01230 sme01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH: sme00030 sme01200 sme01100 sme01120]
M00633 Semi-phosphorylative Entner-Doudoroff pathway, gluconate/galactonate => glycerate-3P [PATH: sme00030 sme00052 sme01200 sme01100]
M00309 Non-phosphorylative Entner-Doudoroff pathway, gluconate/galactonate => glycerate [PATH: sme00030 sme00052 sme01200 sme01100 sme01120]
Other carbohydrate metabolism
M00014 Glucuronate pathway (uronate pathway) [PATH: sme00040 sme01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH: sme00040 sme00030 sme01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH: sme00052 sme01100]
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH: sme00052 sme01100]
M00550 Ascorbate degradation, ascorbate => D-xylulose-5P [PATH: sme00053 sme01100 sme01120]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH: sme00500 sme01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH: sme00500 sme01100]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH: sme00500 sme01100 sme01110]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH: sme00520 sme01250 sme01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH: sme00520 sme00052 sme01250 sme01100]
M00892 UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc [PATH: sme00520 sme01250 sme01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH: sme00520 sme01250 sme01100]
M00012 Glyoxylate cycle [PATH: sme00630 sme01200 sme01100 sme01110]
M00373 Ethylmalonyl pathway [PATH: sme00630 sme01200 sme01100 sme01120]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH: sme00280 sme00630 sme00640 sme01200 sme01100]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH: sme00562 sme01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH: sme00562 sme01100]
Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
Lipid metabolism
Fatty acid metabolism
Sterol biosynthesis
M00101 Cholesterol biosynthesis, FPP => cholesterol [PATH: sme01100]
M00103 Cholecalciferol biosynthesis [PATH: sme01100]
M00107 Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone [PATH: sme01100]
M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone [PATH: sme01100]
M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [PATH: sme01100]
M00976 C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone [PATH: sme01100]
Lipid metabolism
Nucleotide metabolism
Purine metabolism
Pyrimidine metabolism
Amino acid metabolism
Serine and threonine metabolism
Cysteine and methionine metabolism
Branched-chain amino acid metabolism
Lysine metabolism
Arginine and proline metabolism
Polyamine biosynthesis
Histidine metabolism
Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH: sme00400 sme01230 sme01100 sme01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH: sme00400 sme01230 sme01100 sme01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH: sme00400 sme01230 sme01100 sme01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH: sme00400 sme01230 sme01100]
M00040 Tyrosine biosynthesis, chorismate => arogenate => tyrosine [PATH: sme00400 sme01230 sme01100 sme01110]
M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH: sme00350 sme01100]
M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH: sme00350 sme01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH: sme00350 sme01100]
M00037 Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin [PATH: sme00380 sme01100]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH: sme00380 sme01100]
Other amino acid metabolism
Glycan metabolism
Glycan biosynthesis
M00055 N-glycan precursor biosynthesis [PATH: sme01100]
M00073 N-glycan precursor trimming [PATH: sme01100]
M00075 N-glycan biosynthesis, complex type [PATH: sme01100]
M00872 O-glycan biosynthesis, mannose type (core M3) [PATH: sme01100]
M00065 GPI-anchor biosynthesis, core oligosaccharide [PATH: sme01100]
M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer [PATH: sme01100]
M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer [PATH: sme01100]
M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 [PATH: sme01100]
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH: sme00730 sme01240 sme01100]
M00896 Thiamine biosynthesis, archaea, AIR (+ NAD+) => TMP/TPP [PATH: sme00730 sme01240 sme01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH: sme00740 sme01240 sme01100 sme01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH: sme00750 sme01240 sme01100]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH: sme00750 sme01240 sme01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH: sme00760 sme01240 sme01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH: sme00770 sme01240 sme01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH: sme00780 sme01240 sme01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH: sme00785 sme01240 sme01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH: sme00785 sme01240 sme01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH: sme00785 sme01240 sme01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH: sme00790 sme00670 sme01240 sme01100]
M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4 [PATH: sme00790 sme01240 sme01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH: sme00790 sme01240 sme01100]
M00140 C1-unit interconversion, prokaryotes [PATH: sme00670 sme01240 sme01100]
M00141 C1-unit interconversion, eukaryotes [PATH: sme00670 sme01240 sme01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH: sme00860 sme01240 sme01100 sme01110]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH: sme00860 sme01240 sme01100 sme01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH: sme00860 sme01240 sme01100 sme01110]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH: sme00860 sme01240 sme01100]
M00925 Cobalamin biosynthesis, aerobic, uroporphyrinogen III => precorrin 2 => cobyrinate a,c-diamide [PATH: sme00860 sme01240 sme01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH: sme00860 sme01240 sme01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH: sme00130 sme01240 sme01100 sme01110]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinol [PATH: sme00130 sme01240 sme01100]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH: sme00130 sme01240 sme01100 sme01110]
Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Signature modules
Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
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