KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:vcj00010 vcj01200 vcj01230 vcj01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:vcj00010 vcj00020 vcj01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:vcj00010 vcj00020 vcj00620 vcj00785 vcj01200 vcj01210 vcj01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:vcj00020 vcj01200 vcj01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:vcj00020 vcj01200 vcj01210 vcj01230 vcj01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:vcj00020 vcj01200 vcj01210 vcj01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:vcj00030 vcj01200 vcj01100 vcj01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:vcj00030 vcj01200 vcj01100 vcj01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:vcj00030 vcj01200 vcj01230 vcj01100 vcj01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:vcj00030 vcj00230 vcj01200 vcj01230 vcj01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:vcj00030 vcj01200 vcj01100 vcj01120]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:vcj00052 vcj01100]
M00550 Ascorbate degradation, ascorbate => D-xylulose-5P [PATH:vcj00053 vcj01100 vcj01120]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:vcj00500 vcj01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:vcj00500 vcj01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:vcj00520 vcj00052 vcj01250 vcj01100]
M00012 Glyoxylate cycle [PATH:vcj00630 vcj01200 vcj01100 vcj01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:vcj00620 vcj01200 vcj01100 vcj01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:vcj00430 vcj00620 vcj01200 vcj01100 vcj01120]

Methane metabolism
Nitrogen metabolism
Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:vcj00920 vcj01100 vcj01120]

Photosynthesis
ATP synthesis
M00149 Succinate dehydrogenase, prokaryotes [PATH:vcj00190 vcj01100]
M00150 Fumarate reductase, prokaryotes [PATH:vcj00190 vcj01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:vcj00190 vcj01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:vcj00190]
M00156 Cytochrome c oxidase, cbb3-type [PATH:vcj00190 vcj01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:vcj00190 vcj01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:vcj00061 vcj01212 vcj01100]
M00083 Fatty acid biosynthesis, elongation [PATH:vcj00061 vcj01212 vcj01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:vcj00061 vcj00071 vcj01212 vcj01100]
M00087 beta-Oxidation [PATH:vcj00071 vcj01212 vcj01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:vcj00564 vcj01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:vcj00230 vcj01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:vcj00230 vcj01232 vcj01240 vcj01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:vcj00230 vcj01232 vcj01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:vcj00230 vcj00240 vcj01232 vcj01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:vcj00240 vcj01240 vcj01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:vcj00240 vcj01232 vcj01240 vcj01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:vcj00260 vcj00680 vcj01200 vcj01230 vcj01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:vcj00260 vcj01230 vcj01100 vcj01110]
M00621 Glycine cleavage system [PATH:vcj00260 vcj00630 vcj00785 vcj01200 vcj01100]
M00033 Ectoine biosynthesis, aspartate => ectoine [PATH:vcj00260 vcj01210 vcj01230 vcj01100 vcj01120]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:vcj00270 vcj00920 vcj01200 vcj01230 vcj01100 vcj01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:vcj00270 vcj01230 vcj01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:vcj00290 vcj00770 vcj01210 vcj01230 vcj01100 vcj01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:vcj00290 vcj01230 vcj01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:vcj00290 vcj01210 vcj01230 vcj01100 vcj01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:vcj00300 vcj01230 vcj01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:vcj00220 vcj01210 vcj01230 vcj01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:vcj00220 vcj01230 vcj01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:vcj00330 vcj01230 vcj01100]
M00970 Proline degradation, proline => glutamate [PATH:vcj00330 vcj01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:vcj00340 vcj01230 vcj01100 vcj01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:vcj00340 vcj01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:vcj00400 vcj01230 vcj01100 vcj01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:vcj00400 vcj01230 vcj01100 vcj01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:vcj00400 vcj01230 vcj01100 vcj01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:vcj00400 vcj01230 vcj01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:vcj00350 vcj01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:vcj00480 vcj01240 vcj01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:vcj00540 vcj01100]
M00063 CMP-KDO biosynthesis [PATH:vcj00540 vcj01250 vcj01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:vcj00540 vcj01250 vcj01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:vcj00740 vcj01240 vcj01100 vcj01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:vcj00750 vcj01240 vcj01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:vcj00760 vcj01240 vcj01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:vcj00770 vcj01240 vcj01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:vcj00780 vcj01240 vcj01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:vcj00785 vcj01240 vcj01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:vcj00790 vcj01240 vcj01100]
M00140 C1-unit interconversion, prokaryotes [PATH:vcj00670 vcj01240 vcj01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:vcj00860 vcj01240 vcj01100 vcj01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:vcj00860 vcj01240 vcj01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:vcj00130 vcj01240 vcj01100 vcj01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:vcj00130 vcj01240 vcj01100 vcj01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
M00852 Vibrio cholerae pathogenicity signature, toxin coregulated pilus [PATH:vcj05110 vcj05111]
M00850 Vibrio cholerae pathogenicity signature, cholera toxins [PATH:vcj05110]

Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation