[ Network menu | Network entry | Help ]

ENTRY	nt06223
Name	TNF signaling (cancer)
Category	Disease view; Cancer signaling
Display	drug-target relation   disease type

N00446    TNF → TNFRSF1A → (RIPK1+TRADD+TRAF2.. → (TAK1+TAB1/2) → MKK4/7 → JNK → AP1 N00503                    TAX → (MAPK8,MAPK9,MAPK1.. → JUN ⇒ MMP7 N00151            TNF → TNFRSF1A → (RIPK1+TRADD+TRAF2.. → (TAB1/2/3+TAK1) → IKK → NFKBIA → NFKB N01411    Metals → ROS ⊣ PTP ⊣ SRC → ABL → PKD → IKK → NFKBIA → NFKB N00174                    vFLIP → TRAF2 → IKK → NFKBIA → NFKB N00173                K15 → TRAF2 → TAK1 → IKK → NFKBIA → NFKB N01410                    Metals → ROS → IKK → NFKBIA → NFKB N00171                        vFLIP → IKK → NFKBIA → NFKB N00504                        TAX → IKK → NFKBIA → NFKB N00505    CD40LG → CD40 → (TRAF2+TRAF3) → NIK → IKKA → (NFKB2+RELB) N00506            TAX = IKBKG → IKKA → (NFKB2+RELB)