KEGG    Network variation - Telomere length regulation
[ Network menu | Network entry | Help ]
ENTRYnt06510
NameTelomere length regulation
CategoryPathway view; Replication and repair
DiseaseH00507 Dyskeratosis congenita
H02569 Pulmonary fibrosis and/or bone marrow failure, telomere-related
H02251 Cerebroretinal microangiopathy with calcifications and cysts
Display drug-target relation   disease type
N01475    TERC+TGS1→TERC+PAPD5→TERC+PARN+ZCCHC8
    DKCA1/PFBMFT2/AA TERC*
    DKCB6/PFBMFT4     PARN*
    PFBMFT5     ZCCHC8*
N01476    TERC+TERT+Pontin+R..=DKC1+NOP10+NHP2+GA..→TERC+TERT+Pontin+R..=WRAP53+TriC
    DKCA2/PFBMFT1/AA/CMM9 TERT*
    DKCX   DKC1*
    DKCB1/PFBMFT9   NOP10*
    DKCB2   NHP2*
    PFBMFT7   NAF1*
    DKCB3       WRAP53*
    HSNSP       CCT5*
N01477    RTEL1+RAP1+TRF2+TI..=telomerase→Shelterin=CTC1+STN1+TEN1
    DKCA4/PFBMFT3 RTEL1*
    DKCA3_A5 TIN2*
    DKCA6_B7 ACD*
    TPDS3/PFBMFT8/CRMCC3 POT1*
    CRMCC1       CTC1*
    CRMCC2       STN1*

Disease nameDisease category
DKCA1/PFBMFT2/AAH00507Dyskeratosis congenitaRibosomopathy
H02569Pulmonary fibrosis and/or bone marrow failure, telomere-relatedHematologic disease
H01132Aplastic anemiaHematologic disease
DKCB6/PFBMFT4H00507Dyskeratosis congenitaRibosomopathy
H02569Pulmonary fibrosis and/or bone marrow failure, telomere-relatedHematologic disease
PFBMFT5H02569Pulmonary fibrosis and/or bone marrow failure, telomere-relatedHematologic disease
DKCA2/PFBMFT1/AA/CMM9H00507Dyskeratosis congenitaRibosomopathy
H02569Pulmonary fibrosis and/or bone marrow failure, telomere-relatedHematologic disease
H01132Aplastic anemiaHematologic disease
H00038MelanomaCancer
DKCXH00507Dyskeratosis congenitaRibosomopathy
DKCB1/PFBMFT9H00507Dyskeratosis congenitaRibosomopathy
H02569Pulmonary fibrosis and/or bone marrow failure, telomere-relatedHematologic disease
DKCB2H00507Dyskeratosis congenitaRibosomopathy
PFBMFT7H02569Pulmonary fibrosis and/or bone marrow failure, telomere-relatedHematologic disease
DKCB3H00507Dyskeratosis congenitaRibosomopathy
HSNSPH02580Hereditary sensory neuropathy with spastic paraplegiaNervous system disease
DKCA4/PFBMFT3H00507Dyskeratosis congenitaRibosomopathy
H02569Pulmonary fibrosis and/or bone marrow failure, telomere-relatedHematologic disease
DKCA3_A5H00507Dyskeratosis congenitaRibosomopathy
DKCA6_B7H00507Dyskeratosis congenitaRibosomopathy
TPDS3/PFBMFT8/CRMCC3H02624Tumor predisposition syndromeCancer
H02569Pulmonary fibrosis and/or bone marrow failure, telomere-relatedHematologic disease
H02251Cerebroretinal microangiopathy with calcifications and cystsNervous system disease
CRMCC1H02251Cerebroretinal microangiopathy with calcifications and cystsNervous system disease
CRMCC2H02251Cerebroretinal microangiopathy with calcifications and cystsNervous system disease