KEGG Modules
Pathway modules
Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH: mle00010 mle01200 mle01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH: mle00010 mle01200 mle01230 mle01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH: mle00010 mle00020 mle01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH: mle00010 mle00020 mle00620 mle00785 mle01200 mle01210 mle01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH: mle00020 mle01200 mle01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH: mle00020 mle01200 mle01210 mle01230 mle01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH: mle00020 mle01200 mle01210 mle01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH: mle00030 mle01200 mle01100 mle01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH: mle00030 mle01200 mle01100 mle01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH: mle00030 mle01200 mle01230 mle01100 mle01120]
M00580 Pentose phosphate pathway, archaea, fructose 6P => ribose 5P [PATH: mle00030 mle01200 mle01230 mle01100 mle01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH: mle00030 mle00230 mle01200 mle01230 mle01100]
Other carbohydrate metabolism
M00014 Glucuronate pathway (uronate pathway) [PATH: mle00040 mle01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH: mle00052 mle01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH: mle00500 mle01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH: mle00500 mle01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH: mle00520 mle01250 mle01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH: mle00520 mle00052 mle01250 mle01100]
M00892 UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc [PATH: mle00520 mle01250 mle01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH: mle00520 mle01250 mle01100]
M00012 Glyoxylate cycle [PATH: mle00630 mle01200 mle01100 mle01110]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH: mle00280 mle00630 mle00640 mle01200 mle01100]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH: mle00562 mle01100]
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH: mle00562 mle01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH: mle00562 mle01100]
Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
Lipid metabolism
Fatty acid metabolism
Sterol biosynthesis
M00101 Cholesterol biosynthesis, FPP => cholesterol [PATH: mle01100]
M00103 Cholecalciferol biosynthesis [PATH: mle01100]
M00104 Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate [PATH: mle01100]
M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate [PATH: mle01100]
M00862 beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA [PATH: mle01100]
M00107 Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone [PATH: mle01100]
M00108 C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone [PATH: mle01100]
M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone [PATH: mle01100]
M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [PATH: mle01100]
M00976 C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone [PATH: mle01100]
M00977 C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone [PATH: mle01100]
Lipid metabolism
Nucleotide metabolism
Purine metabolism
Pyrimidine metabolism
Amino acid metabolism
Serine and threonine metabolism
Cysteine and methionine metabolism
Branched-chain amino acid metabolism
Lysine metabolism
Arginine and proline metabolism
Polyamine biosynthesis
Histidine metabolism
Aromatic amino acid metabolism
Other amino acid metabolism
Glycan metabolism
Glycan biosynthesis
M00055 N-glycan precursor biosynthesis [PATH: mle01100]
M00073 N-glycan precursor trimming [PATH: mle01100]
M00075 N-glycan biosynthesis, complex type [PATH: mle01100]
M00065 GPI-anchor biosynthesis, core oligosaccharide [PATH: mle01100]
M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer [PATH: mle01100]
M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer [PATH: mle01100]
M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer [PATH: mle01100]
M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 [PATH: mle01100]
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:mle00730 mle01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:mle00740 mle01240 mle01100 mle01110]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:mle00750 mle01240 mle01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:mle00760 mle01240 mle01100]
M00912 NAD biosynthesis, tryptophan => quinolinate => NAD [PATH:mle00380 mle00760 mle01240 mle01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:mle00770 mle01240 mle01100 mle01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:mle00770 mle01240 mle01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:mle00780 mle01240 mle01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:mle00785 mle01240 mle01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:mle00785 mle01240 mle01100]
M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4 [PATH:mle00790 mle01240 mle01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:mle00790 mle01240 mle01100]
M00140 C1-unit interconversion, prokaryotes [PATH:mle00670 mle01240 mle01100]
M00141 C1-unit interconversion, eukaryotes [PATH:mle00670 mle01240 mle01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:mle00860 mle01240 mle01100 mle01110]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:mle00860 mle01240 mle01100 mle01110]
M00926 Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme [PATH:mle00860 mle01240 mle01100]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinol [PATH:mle00130 mle01240 mle01100]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:mle00130 mle01240 mle01100 mle01110]
Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Signature modules
Gene set
Pathogenicity
Drug resistance
M00625 Methicillin resistance [PATH:mle01501]
M00704 Tetracycline resistance, efflux pump Tet38
M00725 Cationic antimicrobial peptide (CAMP) resistance, dltABCD operon [PATH:mle01503]
M00726 Cationic antimicrobial peptide (CAMP) resistance, lysyl-phosphatidylglycerol (L-PG) synthase MprF [PATH:mle01503]
M00700 Multidrug resistance, efflux pump AbcA
Plant pathogenicity
Symbiosis
Module set
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